NLRP6 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	NLRP6
Entrez Gene ID	171389
Full Name	NLR family pyrin domain containing 6
Synonyms	AVR,CLR11.4,NALP6,NAVR,NAVR/AVR,PAN3,PYPAF5
General protein information	Preferred Names NLR family pyrin domain containing 6 Names NACHT, LRR and PYD domains-containing protein 6 NACHT, leucine rich repeat and PYD containing 6 PYRIN-containing APAF1-like protein 5 angiotensin II/vasopressin receptor nucleotide-binding oligomerization domain, leucine rich repeat and pyrin domain containing 6
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 11 Map Location: 11p15.5
Summary	The protein encoded by this gene binds arginine-vasopressin and may be involved in the arginine-vasopressin-mediated regulation of renal salt-water balance. The encoded protein also mediates inflammatory responses in the colon to allow recovery from intestinal epithelial damage and protects against tumorigenesis and the development of colitis. Finally, this protein can increase activation of NF-kappa-B, activation of CASP1 through interaction with ASC, and cAMP accumulation. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2013].
Disorder MIM:	609650

mRNA and Protein(s)

mRNA	Protein	Name
NM_138329.2	NP_612202.2	NACHT, LRR and PYD domains-containing protein 6 isoform 1
NM_001276700.2	NP_001263629.1	NACHT, LRR and PYD domains-containing protein 6 isoform 2
XM_017017253.2	XP_016872742.1	NACHT, LRR and PYD domains-containing protein 6 isoform X1
XM_017017252.1	XP_016872741.1	NACHT, LRR and PYD domains-containing protein 6 isoform X1
XM_017017253.1	XP_016872742.1	NACHT, LRR and PYD domains-containing protein 6 isoform X2
XM_011519931.1	XP_011518233.1	NACHT, LRR and PYD domains-containing protein 6 isoform X3
NM_001276700.1	NP_001263629.1	NACHT, LRR and PYD domains-containing protein 6 isoform 2

Pathways from BioSystems

Homologies

Canis lupus familiaris (dog)	NLRP6	XP_540513.3
Bos taurus (cattle)	NLRP6	XP_002683779.2
Rattus norvegicus (Norway rat)	LOC100912017	XP_006230648.1
	NLRP6	NP_001107586.1
Mus musculus (house mouse)	Nlrp6	NP_598707.2
Rattus norvegicus (Norway rat)	Nlrp6	NP_599202.2
Pan troglodytes (chimpanzee)	NLRP6	XP_521701.3
Homo sapiens (human)	NLRP6	NP_001263629.1

Gene Ontology
Bibliography

Related articles in PubMed

NLRP6 facilitates the interaction between TAB2/3 and TRIM38 in rheumatoid arthritis fibroblast-like synoviocytes.
Lin Y, Luo Z
FEBS letters591(8)1141-1149(2017 04)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Data suggest that mRNA/protein levels of NLRP6 are down-regulated in synovial tissues and synoviocytes of rheumatoid arthritis (RA) patients compared to osteoarthritis patients; NLRP6 provides docking site to facilitate interaction between TAB2/3 and TRIM38 in RA synoviocytes in response to TNFalpha. (NLRP6 = ; TAB2/3 = transforming growth factor-b-activated kinase 1-binding protein 2/3; TRIM38 = tripartite motif 38)
Title: NLRP6 facilitates the interaction between TAB2/3 and TRIM38 in rheumatoid arthritis fibroblast-like synoviocytes.

this review discuss recent findings related to NLRP6 activity, while highlighting outstanding questions and future perspectives in elucidating its roles in health and disease
Title: NLRP6: A Multifaceted Innate Immune Sensor.

We will focus on NLRP6 and NLRP12.
Title: Role of Nlrp6 and Nlrp12 in the maintenance of intestinal homeostasis.

NLRP6 is a newly characterized member of this family that inhibits NF-kappaB and MAP-kinase dependent immune signaling to hamper anti-microbial defense.
Title: NLRP6 in infection and inflammation.

Our results revealed an association between NLRP6/AVR and ADM loci with male essential hypertension, suggesting the existence of sex-specific NLRP6/AVR and ADM variants affecting male susceptibility to essential hypertension.
Title: Sex-specific effects of NLRP6/AVR and ADM loci on susceptibility to essential hypertension in a Sardinian population.

The following NLRP6 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the NLRP6 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu21827	NM_138329.2 Latest version!	Homo sapiens NLR family pyrin domain containing 6 (NLRP6), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$449.50-$629.30 $899.00
OHu91970	XM_017017253.2 Latest version!	Homo sapiens NLR family pyrin domain containing 6 (NLRP6), transcript variant X3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	10-12	$391.30 $559.00
OHu20628	NM_001276700.2 Latest version!	Homo sapiens NLR family pyrin domain containing 6 (NLRP6), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$475.30 $679.00
OHu77447	XM_011519931.1 Latest version!	Homo sapiens NLR family, pyrin domain containing 6 (NLRP6), transcript variant X4, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$391.30 $559.00
OHu91969	XM_017017252.1 Latest version!	Homo sapiens NLR family, pyrin domain containing 6 (NLRP6), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$391.30 $559.00
View Old Accession Versions >>
OHu91970	XM_017017253.1	Homo sapiens NLR family, pyrin domain containing 6 (NLRP6), transcript variant X3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	10-12	$391.30 $559.00
OHu20628	NM_001276700.1	Homo sapiens NLR family pyrin domain containing 6 (NLRP6), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$475.30 $679.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

NLRP6 ( NM_138329.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_612202.2 Homo sapiens NLR family pyrin domain containing 6 (NLRP6), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu21827
Clone ID Related Accession (Same CDS sequence)	NM_138329.2
Accession Version	NM_138329.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2679bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-27
Organism	Homo sapiens(human)
Product	NACHT, LRR and PYD domains-containing protein 6 isoform 1
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AF479748.1, AC136475.7 and CD636365.1. This sequence is a reference standard in the RefSeqGene project. On Feb 22, 2013 this sequence version replaced NM_138329.1. Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AF479748.1, AY154461.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2144835, SAMEA2152474 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## RefSeq Select criteria :: based on conservation, expression, longest protein ##RefSeq-Attributes-END##

ATGGACCAGC CAGAGGCCCC CTGCTCCAGC ACGGGGCCGC GCCTCGCGGT GGCCCGCGAG 
CTGCTCCTGG CTGCGCTGGA GGAACTGAGC CAAGAGCAGC TGAAGCGCTT CCGCCACAAG 
CTGCGCGACG TGGGCCCGGA CGGACGCAGC ATCCCGTGGG GGCGGCTGGA GCGCGCGGAC 
GCCGTGGACC TCGCGGAGCA GCTGGCCCAG TTCTACGGCC CGGAGCCTGC CCTGGAGGTG 
GCCCGCAAGA CCCTCAAGAG GGCGGACGCG CGCGACGTGG CGGCGCAGCT CCAGGAGCGG 
CGGCTGCAGC GGCTCGGGCT CGGCTCCGGG ACGCTGCTCT CCGTGTCCGA GTACAAGAAG 
AAGTACCGGG AGCACGTGCT GCAGCTGCAC GCTCGGGTGA AGGAGAGGAA CGCCCGCTCC 
GTGAAGATCA CCAAGCGCTT CACCAAGCTG CTCATCGCGC CCGAGAGCGC CGCCCCGGAG 
GAGGCGATGG GGCCCGCGGA AGAGCCTGAG CCGGGGCGCG CGCGGCGCTC GGACACGCAC 
ACTTTCAACC GCCTCTTCCG CCGCGACGAG GAGGGCCGGC GGCCGCTGAC CGTGGTGCTG 
CAGGGCCCGG CGGGCATCGG CAAGACCATG GCGGCCAAAA AGATCCTGTA CGACTGGGCG 
GCGGGCAAGC TGTACCAGGG CCAGGTGGAC TTCGCCTTCT TCATGCCCTG CGGCGAGCTG 
CTGGAGAGGC CGGGCACGCG CAGCCTGGCT GACCTGATCC TGGACCAGTG CCCCGACCGC 
GGCGCGCCGG TGCCGCAGAT GCTGGCCCAG CCGCAGCGGC TGCTCTTCAT CCTGGACGGC 
GCGGACGAGC TGCCGGCGCT GGGGGGCCCC GAGGCCGCGC CCTGCACAGA CCCCTTCGAG 
GCGGCGAGCG GCGCGCGGGT GCTAGGCGGG CTGCTGAGCA AGGCGCTGCT GCCCACGGCC 
CTCCTGCTGG TGACCACGCG CGCCGCCGCC CCCGGGAGGC TGCAGGGCCG CCTGTGTTCC 
CCGCAGTGCG CCGAGGTGCG CGGCTTCTCC GACAAGGACA AGAAGAAGTA TTTCTACAAG 
TATTTCCGGG ATGAGAGGAG GGCCGAGCGC GCCTACCGCT TCGTGAAGGA GAACGAGACG 
CTGTTCGCGC TGTGCTTCGT GCCCTTCGTG TGCTGGATCG TGTGCACCGT GCTGCGCCAG 
CAGCTGGAGC TCGGTCGGGA CCTGTCGCGC ACGTCCAAGA CCACCACGTC AGTGTACCTG 
CTTTTCATCA CCAGCGTTCT GAGCTCGGCT CCGGTAGCCG ACGGGCCCCG GTTGCAGGGC 
GACCTGCGCA ATCTGTGCCG CCTGGCCCGC GAGGGCGTCC TCGGACGCAG GGCGCAGTTT 
GCCGAGAAGG AACTGGAGCA ACTGGAGCTT CGTGGCTCCA AAGTGCAGAC GCTGTTTCTC 
AGCAAAAAGG AGCTGCCGGG CGTGCTGGAG ACAGAGGTCA CCTACCAGTT CATCGACCAG 
AGCTTCCAGG AGTTCCTCGC GGCACTGTCC TACCTGCTGG AGGACGGCGG GGTGCCCAGG 
ACCGCGGCTG GCGGCGTTGG GACACTCCTG CGTGGGGACG CCCAGCCGCA CAGCCACTTG 
GTGCTCACCA CGCGCTTCCT CTTCGGACTG CTGAGCGCGG AGCGGATGCG CGACATCGAG 
CGCCACTTCG GCTGCATGGT TTCAGAGCGT GTGAAGCAGG AGGCCCTGCG GTGGGTGCAG 
GGACAGGGAC AGGGCTGCCC CGGAGTGGCA CCAGAGGTGA CCGAGGGGGC CAAAGGGCTC 
GAGGACACCG AAGAGCCAGA GGAGGAGGAG GAGGGAGAGG AGCCCAACTA CCCACTGGAG 
TTGCTGTACT GCCTGTACGA GACGCAGGAG GACGCGTTTG TGCGCCAAGC CCTGTGCCGG 
TTCCCGGAGC TGGCGCTGCA GCGAGTGCGC TTCTGCCGCA TGGACGTGGC TGTTCTGAGC 
TACTGCGTGA GGTGCTGCCC TGCTGGACAG GCACTGCGGC TGATCAGCTG CAGATTGGTT 
GCTGCGCAGG AGAAGAAGAA GAAGAGCCTG GGGAAGCGGC TCCAGGCCAG CCTGGGTGGC 
GGCAGCAGTT CTCAAGGCAC CACAAAACAA CTGCCAGCCT CCCTTCTTCA TCCACTCTTT 
CAGGCAATGA CTGACCCACT GTGCCATCTG AGCAGCCTCA CGCTGTCCCA CTGCAAACTC 
CCTGACGCGG TCTGCCGAGA CCTTTCTGAG GCCCTGAGGG CAGCCCCCGC ACTGACGGAG 
CTGGGCCTCC TCCACAACAG GCTCAGTGAG GCGGGACTGC GTATGCTGAG TGAGGGCCTA 
GCCTGGCCGC AGTGCAGGGT GCAGACGGTC AGGGTACAGC TGCCTGACCC CCAGCGAGGG 
CTCCAGTACC TGGTGGGTAT GCTTCGGCAG AGCCCTGCCC TGACCACCCT GGATCTCAGC 
GGCTGCCAAC TGCCCGCCCC CATGGTGACC TACCTGTGTG CAGTCCTGCA GCACCAGGGA 
TGCGGCCTGC AGACCCTCAG TCTGGCCTCT GTGGAGCTGA GCGAGCAGTC ACTACAGGAG 
CTTCAGGCTG TGAAGAGAGC AAAGCCGGAT CTGGTCATCA CACACCCAGC GCTGGACGGC 
CACCCACAAC CTCCCAAGGA ACTCATCTCG ACCTTCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_612202.2
CDS	1..2679
Translation	MDQPEAPCSSTGPRLAVARELLLAALEELSQEQLKRFRHKLRDVGPDGRSIPWGRLERADAVDLAEQLAQFYGPEPALEVARKTLKRADARDVAAQLQERRLQRLGLGSGTLLSVSEYKKKYREHVLQLHARVKERNARSVKITKRFTKLLIAPESAAPEEAMGPAEEPEPGRARRSDTHTFNRLFRRDEEGRRPLTVVLQGPAGIGKTMAAKKILYDWAAGKLYQGQVDFAFFMPCGELLERPGTRSLADLILDQCPDRGAPVPQMLAQPQRLLFILDGADELPALGGPEAAPCTDPFEAASGARVLGGLLSKALLPTALLLVTTRAAAPGRLQGRLCSPQCAEVRGFSDKDKKKYFYKYFRDERRAERAYRFVKENETLFALCFVPFVCWIVCTVLRQQLELGRDLSRTSKTTTSVYLLFITSVLSSAPVADGPRLQGDLRNLCRLAREGVLGRRAQFAEKELEQLELRGSKVQTLFLSKKELPGVLETEVTYQFIDQSFQEFLAALSYLLEDGGVPRTAAGGVGTLLRGDAQPHSHLVLTTRFLFGLLSAERMRDIERHFGCMVSERVKQEALRWVQGQGQGCPGVAPEVTEGAKGLEDTEEPEEEEEGEEPNYPLELLYCLYETQEDAFVRQALCRFPELALQRVRFCRMDVAVLSYCVRCCPAGQALRLISCRLVAAQEKKKKSLGKRLQASLGGGSSSQGTTKQLPASLLHPLFQAMTDPLCHLSSLTLSHCKLPDAVCRDLSEALRAAPALTELGLLHNRLSEAGLRMLSEGLAWPQCRVQTVRVQLPDPQRGLQYLVGMLRQSPALTTLDLSGCQLPAPMVTYLCAVLQHQGCGLQTLSLASVELSEQSLQELQAVKRAKPDLVITHPALDGHPQPPKELISTF

Target ORF information:

RefSeq Version	NM_138329.2
Organism	Homo sapiens(human)
Definition	Homo sapiens NLR family pyrin domain containing 6 (NLRP6), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_138329.2

ORF Insert Sequence:

ATGGACCAGC CAGAGGCCCC CTGCTCCAGC ACGGGGCCGC GCCTCGCGGT GGCCCGCGAG 
CTGCTCCTGG CTGCGCTGGA GGAACTGAGC CAAGAGCAGC TGAAGCGCTT CCGCCACAAG 
CTGCGCGACG TGGGCCCGGA CGGACGCAGC ATCCCGTGGG GGCGGCTGGA GCGCGCGGAC 
GCCGTGGACC TCGCGGAGCA GCTGGCCCAG TTCTACGGCC CGGAGCCTGC CCTGGAGGTG 
GCCCGCAAGA CCCTCAAGAG GGCGGACGCG CGCGACGTGG CGGCGCAGCT CCAGGAGCGG 
CGGCTGCAGC GGCTCGGGCT CGGCTCCGGG ACGCTGCTCT CCGTGTCCGA GTACAAGAAG 
AAGTACCGGG AGCACGTGCT GCAGCTGCAC GCTCGGGTGA AGGAGAGGAA CGCCCGCTCC 
GTGAAGATCA CCAAGCGCTT CACCAAGCTG CTCATCGCGC CCGAGAGCGC CGCCCCGGAG 
GAGGCGATGG GGCCCGCGGA AGAGCCTGAG CCGGGGCGCG CGCGGCGCTC GGACACGCAC 
ACTTTCAACC GCCTCTTCCG CCGCGACGAG GAGGGCCGGC GGCCGCTGAC CGTGGTGCTG 
CAGGGCCCGG CGGGCATCGG CAAGACCATG GCGGCCAAAA AGATCCTGTA CGACTGGGCG 
GCGGGCAAGC TGTACCAGGG CCAGGTGGAC TTCGCCTTCT TCATGCCCTG CGGCGAGCTG 
CTGGAGAGGC CGGGCACGCG CAGCCTGGCT GACCTGATCC TGGACCAGTG CCCCGACCGC 
GGCGCGCCGG TGCCGCAGAT GCTGGCCCAG CCGCAGCGGC TGCTCTTCAT CCTGGACGGC 
GCGGACGAGC TGCCGGCGCT GGGGGGCCCC GAGGCCGCGC CCTGCACAGA CCCCTTCGAG 
GCGGCGAGCG GCGCGCGGGT GCTAGGCGGG CTGCTGAGCA AGGCGCTGCT GCCCACGGCC 
CTCCTGCTGG TGACCACGCG CGCCGCCGCC CCCGGGAGGC TGCAGGGCCG CCTGTGTTCC 
CCGCAGTGCG CCGAGGTGCG CGGCTTCTCC GACAAGGACA AGAAGAAGTA TTTCTACAAG 
TATTTCCGGG ATGAGAGGAG GGCCGAGCGC GCCTACCGCT TCGTGAAGGA GAACGAGACG 
CTGTTCGCGC TGTGCTTCGT GCCCTTCGTG TGCTGGATCG TGTGCACCGT GCTGCGCCAG 
CAGCTGGAGC TCGGTCGGGA CCTGTCGCGC ACGTCCAAGA CCACCACGTC AGTGTACCTG 
CTTTTCATCA CCAGCGTTCT GAGCTCGGCT CCGGTAGCCG ACGGGCCCCG GTTGCAGGGC 
GACCTGCGCA ATCTGTGCCG CCTGGCCCGC GAGGGCGTCC TCGGACGCAG GGCGCAGTTT 
GCCGAGAAGG AACTGGAGCA ACTGGAGCTT CGTGGCTCCA AAGTGCAGAC GCTGTTTCTC 
AGCAAAAAGG AGCTGCCGGG CGTGCTGGAG ACAGAGGTCA CCTACCAGTT CATCGACCAG 
AGCTTCCAGG AGTTCCTCGC GGCACTGTCC TACCTGCTGG AGGACGGCGG GGTGCCCAGG 
ACCGCGGCTG GCGGCGTTGG GACACTCCTG CGTGGGGACG CCCAGCCGCA CAGCCACTTG 
GTGCTCACCA CGCGCTTCCT CTTCGGACTG CTGAGCGCGG AGCGGATGCG CGACATCGAG 
CGCCACTTCG GCTGCATGGT TTCAGAGCGT GTGAAGCAGG AGGCCCTGCG GTGGGTGCAG 
GGACAGGGAC AGGGCTGCCC CGGAGTGGCA CCAGAGGTGA CCGAGGGGGC CAAAGGGCTC 
GAGGACACCG AAGAGCCAGA GGAGGAGGAG GAGGGAGAGG AGCCCAACTA CCCACTGGAG 
TTGCTGTACT GCCTGTACGA GACGCAGGAG GACGCGTTTG TGCGCCAAGC CCTGTGCCGG 
TTCCCGGAGC TGGCGCTGCA GCGAGTGCGC TTCTGCCGCA TGGACGTGGC TGTTCTGAGC 
TACTGCGTGA GGTGCTGCCC TGCTGGACAG GCACTGCGGC TGATCAGCTG CAGATTGGTT 
GCTGCGCAGG AGAAGAAGAA GAAGAGCCTG GGGAAGCGGC TCCAGGCCAG CCTGGGTGGC 
GGCAGCAGTT CTCAAGGCAC CACAAAACAA CTGCCAGCCT CCCTTCTTCA TCCACTCTTT 
CAGGCAATGA CTGACCCACT GTGCCATCTG AGCAGCCTCA CGCTGTCCCA CTGCAAACTC 
CCTGACGCGG TCTGCCGAGA CCTTTCTGAG GCCCTGAGGG CAGCCCCCGC ACTGACGGAG 
CTGGGCCTCC TCCACAACAG GCTCAGTGAG GCGGGACTGC GTATGCTGAG TGAGGGCCTA 
GCCTGGCCGC AGTGCAGGGT GCAGACGGTC AGGGTACAGC TGCCTGACCC CCAGCGAGGG 
CTCCAGTACC TGGTGGGTAT GCTTCGGCAG AGCCCTGCCC TGACCACCCT GGATCTCAGC 
GGCTGCCAAC TGCCCGCCCC CATGGTGACC TACCTGTGTG CAGTCCTGCA GCACCAGGGA 
TGCGGCCTGC AGACCCTCAG TCTGGCCTCT GTGGAGCTGA GCGAGCAGTC ACTACAGGAG 
CTTCAGGCTG TGAAGAGAGC AAAGCCGGAT CTGGTCATCA CACACCCAGC GCTGGACGGC 
CACCCACAAC CTCCCAAGGA ACTCATCTCG ACCTTCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

NLRP6 ( XM_017017253.2 ) cDNA ORF clone, Homo sapiens(human) -> XP_016872742.1 Homo sapiens NLR family pyrin domain containing 6 (NLRP6), transcript variant X3, mRNA.

Price & Availability↑

CloneID	OHu91970
Clone ID Related Accession (Same CDS sequence)	XM_017017253.2 , XM_017017253.1
Accession Version	XM_017017253.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2193bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	NACHT, LRR and PYD domains-containing protein 6 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000011.10) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Mar 26, 2018 this sequence version replaced XM_017017253.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGGGCCCG CGGAAGAGCC TGAGCCGGGG CGCGCGCGGC GCTCGGACAC GCACACTTTC 
AACCGCCTCT TCCGCCGCGA CGAGGAGGGC CGGCGGCCGC TGACCGTGGT GCTGCAGGGC 
CCGGCGGGCA TCGGCAAGAC CATGGCGGCC AAAAAGATCC TGTACGACTG GGCGGCGGGC 
AAGCTGTACC AGGGCCAGGT GGACTTCGCC TTCTTCATGC CCTGCGGCGA GCTGCTGGAG 
AGGCCGGGCA CGCGCAGCCT GGCTGACCTG ATCCTGGACC AGTGCCCCGA CCGCGGCGCG 
CCGGTGCCGC AGATGCTGGC CCAGCCGCAG CGGCTGCTCT TCATCCTGGA CGGCGCGGAC 
GAGCTGCCGG CGCTGGGGGG CCCCGAGGCC GCGCCCTGCA CAGACCCCTT CGAGGCGGCG 
AGCGGCGCGC GGGTGCTAGG CGGGCTGCTG AGCAAGGCGC TGCTGCCCAC GGCCCTCCTG 
CTGGTGACCA CGCGCGCCGC CGCCCCCGGG AGGCTGCAGG GCCGCCTGTG TTCCCCGCAG 
TGCGCCGAGG TGCGCGGCTT CTCCGACAAG GACAAGAAGA AGTATTTCTA CAAGTATTTC 
CGGGATGAGA GGAGGGCCGA GCGCGCCTAC CGCTTCGTGA AGGAGAACGA GACGCTGTTC 
GCGCTGTGCT TCGTGCCCTT CGTGTGCTGG ATCGTGTGCA CCGTGCTGCG CCAGCAGCTG 
GAGCTCGGTC GGGACCTGTC GCGCACGTCC AAGACCACCA CGTCAGTGTA CCTGCTTTTC 
ATCACCAGCG TTCTGAGCTC GGCTCCGGTA GCCGACGGGC CCCGGTTGCA GGGCGACCTG 
CGCAATCTGT GCCGCCTGGC CCGCGAGGGC GTCCTCGGAC GCAGGGCGCA GTTTGCCGAG 
AAGGAACTGG AGCAACTGGA GCTTCGTGGC TCCAAAGTGC AGACGCTGTT TCTCAGCAAA 
AAGGAGCTGC CGGGCGTGCT GGAGACAGAG GTCACCTACC AGTTCATCGA CCAGAGCTTC 
CAGGAGTTCC TCGCGGCACT GTCCTACCTG CTGGAGGACG GCGGGGTGCC CAGGACCGCG 
GCTGGCGGCG TTGGGACACT CCTGCGTGGG GACGCCCAGC CGCACAGCCA CTTGGTGCTC 
ACCACGCGCT TCCTCTTCGG ACTGCTGAGC GCGGAGCGGA TGCGCGACAT CGAGCGCCAC 
TTCGGCTGCA TGGTTTCAGA GCGTGTGAAG CAGGAGGCCC TGCGGTGGGT GCAGGGACAG 
GGACAGGGCT GCCCCGGAGT GGCACCAGAG GTGACCGAGG GGGCCAAAGG GCTCGAGGAC 
ACCGAAGAGC CAGAGGAGGA GGAGGAGGGA GAGGAGCCCA ACTACCCACT GGAGTTGCTG 
TACTGCCTGT ACGAGACGCA GGAGGACGCG TTTGTGCGCC AAGCCCTGTG CCGGTTCCCG 
GAGCTGGCGC TGCAGCGAGT GCGCTTCTGC CGCATGGACG TGGCTGTTCT GAGCTACTGC 
GTGAGGTGCT GCCCTGCTGG ACAGGCACTG CGGCTGATCA GCTGCAGATT GGTTGCTGCG 
CAGGAGAAGA AGAAGAAGAG CCTGGGGAAG CGGCTCCAGG CCAGCCTGGG TGGCGGCAGC 
AGTTCTCAAG GCACCACAAA ACAACTGCCA GCCTCCCTTC TTCATCCACT CTTTCAGGCA 
ATGACTGACC CACTGTGCCA TCTGAGCAGC CTCACGCTGT CCCACTGCAA ACTCCCTGAC 
GCGGTCTGCC GAGACCTTTC TGAGGCCCTG AGGGCAGCCC CCGCACTGAC GGAGCTGGGC 
CTCCTCCACA ACAGGCTCAG TGAGGCGGGA CTGCGTATGC TGAGTGAGGG CCTAGCCTGG 
CCGCAGTGCA GGGTGCAGAC GGTCAGGGTA CAGCTGCCTG ACCCCCAGCG AGGGCTCCAG 
TACCTGGTGG GTATGCTTCG GCAGAGCCCT GCCCTGACCA CCCTGGATCT CAGCGGCTGC 
CAACTGCCCG CCCCCATGGT GACCTACCTG TGTGCAGTCC TGCAGCACCA GGGATGCGGC 
CTGCAGACCC TCAGTCTGGC CTCTGTGGAG CTGAGCGAGC AGTCACTACA GGAGCTTCAG 
GCTGTGAAGA GAGCAAAGCC GGATCTGGTC ATCACACACC CAGCGCTGGA CGGCCACCCA 
CAACCTCCCA AGGAACTCAT CTCGACCTTC TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_016872742.1
CDS	139..2331
Translation	MGPAEEPEPGRARRSDTHTFNRLFRRDEEGRRPLTVVLQGPAGIGKTMAAKKILYDWAAGKLYQGQVDFAFFMPCGELLERPGTRSLADLILDQCPDRGAPVPQMLAQPQRLLFILDGADELPALGGPEAAPCTDPFEAASGARVLGGLLSKALLPTALLLVTTRAAAPGRLQGRLCSPQCAEVRGFSDKDKKKYFYKYFRDERRAERAYRFVKENETLFALCFVPFVCWIVCTVLRQQLELGRDLSRTSKTTTSVYLLFITSVLSSAPVADGPRLQGDLRNLCRLAREGVLGRRAQFAEKELEQLELRGSKVQTLFLSKKELPGVLETEVTYQFIDQSFQEFLAALSYLLEDGGVPRTAAGGVGTLLRGDAQPHSHLVLTTRFLFGLLSAERMRDIERHFGCMVSERVKQEALRWVQGQGQGCPGVAPEVTEGAKGLEDTEEPEEEEEGEEPNYPLELLYCLYETQEDAFVRQALCRFPELALQRVRFCRMDVAVLSYCVRCCPAGQALRLISCRLVAAQEKKKKSLGKRLQASLGGGSSSQGTTKQLPASLLHPLFQAMTDPLCHLSSLTLSHCKLPDAVCRDLSEALRAAPALTELGLLHNRLSEAGLRMLSEGLAWPQCRVQTVRVQLPDPQRGLQYLVGMLRQSPALTTLDLSGCQLPAPMVTYLCAVLQHQGCGLQTLSLASVELSEQSLQELQAVKRAKPDLVITHPALDGHPQPPKELISTF

Target ORF information:

RefSeq Version	XM_017017253.2
Organism	Homo sapiens(human)
Definition	Homo sapiens NLR family pyrin domain containing 6 (NLRP6), transcript variant X3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017017253.2

ORF Insert Sequence:

ATGGGGCCCG CGGAAGAGCC TGAGCCGGGG CGCGCGCGGC GCTCGGACAC GCACACTTTC 
AACCGCCTCT TCCGCCGCGA CGAGGAGGGC CGGCGGCCGC TGACCGTGGT GCTGCAGGGC 
CCGGCGGGCA TCGGCAAGAC CATGGCGGCC AAAAAGATCC TGTACGACTG GGCGGCGGGC 
AAGCTGTACC AGGGCCAGGT GGACTTCGCC TTCTTCATGC CCTGCGGCGA GCTGCTGGAG 
AGGCCGGGCA CGCGCAGCCT GGCTGACCTG ATCCTGGACC AGTGCCCCGA CCGCGGCGCG 
CCGGTGCCGC AGATGCTGGC CCAGCCGCAG CGGCTGCTCT TCATCCTGGA CGGCGCGGAC 
GAGCTGCCGG CGCTGGGGGG CCCCGAGGCC GCGCCCTGCA CAGACCCCTT CGAGGCGGCG 
AGCGGCGCGC GGGTGCTAGG CGGGCTGCTG AGCAAGGCGC TGCTGCCCAC GGCCCTCCTG 
CTGGTGACCA CGCGCGCCGC CGCCCCCGGG AGGCTGCAGG GCCGCCTGTG TTCCCCGCAG 
TGCGCCGAGG TGCGCGGCTT CTCCGACAAG GACAAGAAGA AGTATTTCTA CAAGTATTTC 
CGGGATGAGA GGAGGGCCGA GCGCGCCTAC CGCTTCGTGA AGGAGAACGA GACGCTGTTC 
GCGCTGTGCT TCGTGCCCTT CGTGTGCTGG ATCGTGTGCA CCGTGCTGCG CCAGCAGCTG 
GAGCTCGGTC GGGACCTGTC GCGCACGTCC AAGACCACCA CGTCAGTGTA CCTGCTTTTC 
ATCACCAGCG TTCTGAGCTC GGCTCCGGTA GCCGACGGGC CCCGGTTGCA GGGCGACCTG 
CGCAATCTGT GCCGCCTGGC CCGCGAGGGC GTCCTCGGAC GCAGGGCGCA GTTTGCCGAG 
AAGGAACTGG AGCAACTGGA GCTTCGTGGC TCCAAAGTGC AGACGCTGTT TCTCAGCAAA 
AAGGAGCTGC CGGGCGTGCT GGAGACAGAG GTCACCTACC AGTTCATCGA CCAGAGCTTC 
CAGGAGTTCC TCGCGGCACT GTCCTACCTG CTGGAGGACG GCGGGGTGCC CAGGACCGCG 
GCTGGCGGCG TTGGGACACT CCTGCGTGGG GACGCCCAGC CGCACAGCCA CTTGGTGCTC 
ACCACGCGCT TCCTCTTCGG ACTGCTGAGC GCGGAGCGGA TGCGCGACAT CGAGCGCCAC 
TTCGGCTGCA TGGTTTCAGA GCGTGTGAAG CAGGAGGCCC TGCGGTGGGT GCAGGGACAG 
GGACAGGGCT GCCCCGGAGT GGCACCAGAG GTGACCGAGG GGGCCAAAGG GCTCGAGGAC 
ACCGAAGAGC CAGAGGAGGA GGAGGAGGGA GAGGAGCCCA ACTACCCACT GGAGTTGCTG 
TACTGCCTGT ACGAGACGCA GGAGGACGCG TTTGTGCGCC AAGCCCTGTG CCGGTTCCCG 
GAGCTGGCGC TGCAGCGAGT GCGCTTCTGC CGCATGGACG TGGCTGTTCT GAGCTACTGC 
GTGAGGTGCT GCCCTGCTGG ACAGGCACTG CGGCTGATCA GCTGCAGATT GGTTGCTGCG 
CAGGAGAAGA AGAAGAAGAG CCTGGGGAAG CGGCTCCAGG CCAGCCTGGG TGGCGGCAGC 
AGTTCTCAAG GCACCACAAA ACAACTGCCA GCCTCCCTTC TTCATCCACT CTTTCAGGCA 
ATGACTGACC CACTGTGCCA TCTGAGCAGC CTCACGCTGT CCCACTGCAA ACTCCCTGAC 
GCGGTCTGCC GAGACCTTTC TGAGGCCCTG AGGGCAGCCC CCGCACTGAC GGAGCTGGGC 
CTCCTCCACA ACAGGCTCAG TGAGGCGGGA CTGCGTATGC TGAGTGAGGG CCTAGCCTGG 
CCGCAGTGCA GGGTGCAGAC GGTCAGGGTA CAGCTGCCTG ACCCCCAGCG AGGGCTCCAG 
TACCTGGTGG GTATGCTTCG GCAGAGCCCT GCCCTGACCA CCCTGGATCT CAGCGGCTGC 
CAACTGCCCG CCCCCATGGT GACCTACCTG TGTGCAGTCC TGCAGCACCA GGGATGCGGC 
CTGCAGACCC TCAGTCTGGC CTCTGTGGAG CTGAGCGAGC AGTCACTACA GGAGCTTCAG 
GCTGTGAAGA GAGCAAAGCC GGATCTGGTC ATCACACACC CAGCGCTGGA CGGCCACCCA 
CAACCTCCCA AGGAACTCAT CTCGACCTTC TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

NLRP6 ( XM_017017253.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_016872742.1 Homo sapiens NLR family, pyrin domain containing 6 (NLRP6), transcript variant X3, mRNA.

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CloneID	OHu91970
Clone ID Related Accession (Same CDS sequence)	XM_017017253.2 , XM_017017253.1
Accession Version	XM_017017253.1	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2193bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-06-05
Organism	Homo sapiens(human)
Product	NACHT, LRR and PYD domains-containing protein 6 isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000011.10) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGGGCCCG CGGAAGAGCC TGAGCCGGGG CGCGCGCGGC GCTCGGACAC GCACACTTTC 
AACCGCCTCT TCCGCCGCGA CGAGGAGGGC CGGCGGCCGC TGACCGTGGT GCTGCAGGGC 
CCGGCGGGCA TCGGCAAGAC CATGGCGGCC AAAAAGATCC TGTACGACTG GGCGGCGGGC 
AAGCTGTACC AGGGCCAGGT GGACTTCGCC TTCTTCATGC CCTGCGGCGA GCTGCTGGAG 
AGGCCGGGCA CGCGCAGCCT GGCTGACCTG ATCCTGGACC AGTGCCCCGA CCGCGGCGCG 
CCGGTGCCGC AGATGCTGGC CCAGCCGCAG CGGCTGCTCT TCATCCTGGA CGGCGCGGAC 
GAGCTGCCGG CGCTGGGGGG CCCCGAGGCC GCGCCCTGCA CAGACCCCTT CGAGGCGGCG 
AGCGGCGCGC GGGTGCTAGG CGGGCTGCTG AGCAAGGCGC TGCTGCCCAC GGCCCTCCTG 
CTGGTGACCA CGCGCGCCGC CGCCCCCGGG AGGCTGCAGG GCCGCCTGTG TTCCCCGCAG 
TGCGCCGAGG TGCGCGGCTT CTCCGACAAG GACAAGAAGA AGTATTTCTA CAAGTATTTC 
CGGGATGAGA GGAGGGCCGA GCGCGCCTAC CGCTTCGTGA AGGAGAACGA GACGCTGTTC 
GCGCTGTGCT TCGTGCCCTT CGTGTGCTGG ATCGTGTGCA CCGTGCTGCG CCAGCAGCTG 
GAGCTCGGTC GGGACCTGTC GCGCACGTCC AAGACCACCA CGTCAGTGTA CCTGCTTTTC 
ATCACCAGCG TTCTGAGCTC GGCTCCGGTA GCCGACGGGC CCCGGTTGCA GGGCGACCTG 
CGCAATCTGT GCCGCCTGGC CCGCGAGGGC GTCCTCGGAC GCAGGGCGCA GTTTGCCGAG 
AAGGAACTGG AGCAACTGGA GCTTCGTGGC TCCAAAGTGC AGACGCTGTT TCTCAGCAAA 
AAGGAGCTGC CGGGCGTGCT GGAGACAGAG GTCACCTACC AGTTCATCGA CCAGAGCTTC 
CAGGAGTTCC TCGCGGCACT GTCCTACCTG CTGGAGGACG GCGGGGTGCC CAGGACCGCG 
GCTGGCGGCG TTGGGACACT CCTGCGTGGG GACGCCCAGC CGCACAGCCA CTTGGTGCTC 
ACCACGCGCT TCCTCTTCGG ACTGCTGAGC GCGGAGCGGA TGCGCGACAT CGAGCGCCAC 
TTCGGCTGCA TGGTTTCAGA GCGTGTGAAG CAGGAGGCCC TGCGGTGGGT GCAGGGACAG 
GGACAGGGCT GCCCCGGAGT GGCACCAGAG GTGACCGAGG GGGCCAAAGG GCTCGAGGAC 
ACCGAAGAGC CAGAGGAGGA GGAGGAGGGA GAGGAGCCCA ACTACCCACT GGAGTTGCTG 
TACTGCCTGT ACGAGACGCA GGAGGACGCG TTTGTGCGCC AAGCCCTGTG CCGGTTCCCG 
GAGCTGGCGC TGCAGCGAGT GCGCTTCTGC CGCATGGACG TGGCTGTTCT GAGCTACTGC 
GTGAGGTGCT GCCCTGCTGG ACAGGCACTG CGGCTGATCA GCTGCAGATT GGTTGCTGCG 
CAGGAGAAGA AGAAGAAGAG CCTGGGGAAG CGGCTCCAGG CCAGCCTGGG TGGCGGCAGC 
AGTTCTCAAG GCACCACAAA ACAACTGCCA GCCTCCCTTC TTCATCCACT CTTTCAGGCA 
ATGACTGACC CACTGTGCCA TCTGAGCAGC CTCACGCTGT CCCACTGCAA ACTCCCTGAC 
GCGGTCTGCC GAGACCTTTC TGAGGCCCTG AGGGCAGCCC CCGCACTGAC GGAGCTGGGC 
CTCCTCCACA ACAGGCTCAG TGAGGCGGGA CTGCGTATGC TGAGTGAGGG CCTAGCCTGG 
CCGCAGTGCA GGGTGCAGAC GGTCAGGGTA CAGCTGCCTG ACCCCCAGCG AGGGCTCCAG 
TACCTGGTGG GTATGCTTCG GCAGAGCCCT GCCCTGACCA CCCTGGATCT CAGCGGCTGC 
CAACTGCCCG CCCCCATGGT GACCTACCTG TGTGCAGTCC TGCAGCACCA GGGATGCGGC 
CTGCAGACCC TCAGTCTGGC CTCTGTGGAG CTGAGCGAGC AGTCACTACA GGAGCTTCAG 
GCTGTGAAGA GAGCAAAGCC GGATCTGGTC ATCACACACC CAGCGCTGGA CGGCCACCCA 
CAACCTCCCA AGGAACTCAT CTCGACCTTC TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_016872742.1
CDS	171..2363
Translation	MGPAEEPEPGRARRSDTHTFNRLFRRDEEGRRPLTVVLQGPAGIGKTMAAKKILYDWAAGKLYQGQVDFAFFMPCGELLERPGTRSLADLILDQCPDRGAPVPQMLAQPQRLLFILDGADELPALGGPEAAPCTDPFEAASGARVLGGLLSKALLPTALLLVTTRAAAPGRLQGRLCSPQCAEVRGFSDKDKKKYFYKYFRDERRAERAYRFVKENETLFALCFVPFVCWIVCTVLRQQLELGRDLSRTSKTTTSVYLLFITSVLSSAPVADGPRLQGDLRNLCRLAREGVLGRRAQFAEKELEQLELRGSKVQTLFLSKKELPGVLETEVTYQFIDQSFQEFLAALSYLLEDGGVPRTAAGGVGTLLRGDAQPHSHLVLTTRFLFGLLSAERMRDIERHFGCMVSERVKQEALRWVQGQGQGCPGVAPEVTEGAKGLEDTEEPEEEEEGEEPNYPLELLYCLYETQEDAFVRQALCRFPELALQRVRFCRMDVAVLSYCVRCCPAGQALRLISCRLVAAQEKKKKSLGKRLQASLGGGSSSQGTTKQLPASLLHPLFQAMTDPLCHLSSLTLSHCKLPDAVCRDLSEALRAAPALTELGLLHNRLSEAGLRMLSEGLAWPQCRVQTVRVQLPDPQRGLQYLVGMLRQSPALTTLDLSGCQLPAPMVTYLCAVLQHQGCGLQTLSLASVELSEQSLQELQAVKRAKPDLVITHPALDGHPQPPKELISTF

Target ORF information:

RefSeq Version	XM_017017253.1
Organism	Homo sapiens(human)
Definition	Homo sapiens NLR family, pyrin domain containing 6 (NLRP6), transcript variant X3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017017253.1

ORF Insert Sequence:

ATGGGGCCCG CGGAAGAGCC TGAGCCGGGG CGCGCGCGGC GCTCGGACAC GCACACTTTC 
AACCGCCTCT TCCGCCGCGA CGAGGAGGGC CGGCGGCCGC TGACCGTGGT GCTGCAGGGC 
CCGGCGGGCA TCGGCAAGAC CATGGCGGCC AAAAAGATCC TGTACGACTG GGCGGCGGGC 
AAGCTGTACC AGGGCCAGGT GGACTTCGCC TTCTTCATGC CCTGCGGCGA GCTGCTGGAG 
AGGCCGGGCA CGCGCAGCCT GGCTGACCTG ATCCTGGACC AGTGCCCCGA CCGCGGCGCG 
CCGGTGCCGC AGATGCTGGC CCAGCCGCAG CGGCTGCTCT TCATCCTGGA CGGCGCGGAC 
GAGCTGCCGG CGCTGGGGGG CCCCGAGGCC GCGCCCTGCA CAGACCCCTT CGAGGCGGCG 
AGCGGCGCGC GGGTGCTAGG CGGGCTGCTG AGCAAGGCGC TGCTGCCCAC GGCCCTCCTG 
CTGGTGACCA CGCGCGCCGC CGCCCCCGGG AGGCTGCAGG GCCGCCTGTG TTCCCCGCAG 
TGCGCCGAGG TGCGCGGCTT CTCCGACAAG GACAAGAAGA AGTATTTCTA CAAGTATTTC 
CGGGATGAGA GGAGGGCCGA GCGCGCCTAC CGCTTCGTGA AGGAGAACGA GACGCTGTTC 
GCGCTGTGCT TCGTGCCCTT CGTGTGCTGG ATCGTGTGCA CCGTGCTGCG CCAGCAGCTG 
GAGCTCGGTC GGGACCTGTC GCGCACGTCC AAGACCACCA CGTCAGTGTA CCTGCTTTTC 
ATCACCAGCG TTCTGAGCTC GGCTCCGGTA GCCGACGGGC CCCGGTTGCA GGGCGACCTG 
CGCAATCTGT GCCGCCTGGC CCGCGAGGGC GTCCTCGGAC GCAGGGCGCA GTTTGCCGAG 
AAGGAACTGG AGCAACTGGA GCTTCGTGGC TCCAAAGTGC AGACGCTGTT TCTCAGCAAA 
AAGGAGCTGC CGGGCGTGCT GGAGACAGAG GTCACCTACC AGTTCATCGA CCAGAGCTTC 
CAGGAGTTCC TCGCGGCACT GTCCTACCTG CTGGAGGACG GCGGGGTGCC CAGGACCGCG 
GCTGGCGGCG TTGGGACACT CCTGCGTGGG GACGCCCAGC CGCACAGCCA CTTGGTGCTC 
ACCACGCGCT TCCTCTTCGG ACTGCTGAGC GCGGAGCGGA TGCGCGACAT CGAGCGCCAC 
TTCGGCTGCA TGGTTTCAGA GCGTGTGAAG CAGGAGGCCC TGCGGTGGGT GCAGGGACAG 
GGACAGGGCT GCCCCGGAGT GGCACCAGAG GTGACCGAGG GGGCCAAAGG GCTCGAGGAC 
ACCGAAGAGC CAGAGGAGGA GGAGGAGGGA GAGGAGCCCA ACTACCCACT GGAGTTGCTG 
TACTGCCTGT ACGAGACGCA GGAGGACGCG TTTGTGCGCC AAGCCCTGTG CCGGTTCCCG 
GAGCTGGCGC TGCAGCGAGT GCGCTTCTGC CGCATGGACG TGGCTGTTCT GAGCTACTGC 
GTGAGGTGCT GCCCTGCTGG ACAGGCACTG CGGCTGATCA GCTGCAGATT GGTTGCTGCG 
CAGGAGAAGA AGAAGAAGAG CCTGGGGAAG CGGCTCCAGG CCAGCCTGGG TGGCGGCAGC 
AGTTCTCAAG GCACCACAAA ACAACTGCCA GCCTCCCTTC TTCATCCACT CTTTCAGGCA 
ATGACTGACC CACTGTGCCA TCTGAGCAGC CTCACGCTGT CCCACTGCAA ACTCCCTGAC 
GCGGTCTGCC GAGACCTTTC TGAGGCCCTG AGGGCAGCCC CCGCACTGAC GGAGCTGGGC 
CTCCTCCACA ACAGGCTCAG TGAGGCGGGA CTGCGTATGC TGAGTGAGGG CCTAGCCTGG 
CCGCAGTGCA GGGTGCAGAC GGTCAGGGTA CAGCTGCCTG ACCCCCAGCG AGGGCTCCAG 
TACCTGGTGG GTATGCTTCG GCAGAGCCCT GCCCTGACCA CCCTGGATCT CAGCGGCTGC 
CAACTGCCCG CCCCCATGGT GACCTACCTG TGTGCAGTCC TGCAGCACCA GGGATGCGGC 
CTGCAGACCC TCAGTCTGGC CTCTGTGGAG CTGAGCGAGC AGTCACTACA GGAGCTTCAG 
GCTGTGAAGA GAGCAAAGCC GGATCTGGTC ATCACACACC CAGCGCTGGA CGGCCACCCA 
CAACCTCCCA AGGAACTCAT CTCGACCTTC TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

NLRP6 ( NM_001276700.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_001263629.1 Homo sapiens NLR family pyrin domain containing 6 (NLRP6), transcript variant 2, mRNA.

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CloneID	OHu20628
Clone ID Related Accession (Same CDS sequence)	NM_001276700.2 , NM_001276700.1
Accession Version	NM_001276700.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2676bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2020-01-03
Organism	Homo sapiens(human)
Product	NACHT, LRR and PYD domains-containing protein 6 isoform 2
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AC136475.7, AF479748.1, AK292668.1 and CD636365.1. On Jun 2, 2019 this sequence version replaced NM_001276700.1. Transcript Variant: This variant (2) uses an alternate in-frame exon at the 5' end of an exon compared to variant 1. The resulting isoform (2) lacks a single internal aa compared to isoform 1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK292668.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2144835, SAMEA2152474 [ECO:0000348] ##Evidence-Data-END##

ATGGACCAGC CAGAGGCCCC CTGCTCCAGC ACGGGGCCGC GCCTCGCGGT GGCCCGCGAG 
CTGCTCCTGG CTGCGCTGGA GGAACTGAGC CAAGAGCAGC TGAAGCGCTT CCGCCACAAG 
CTGCGCGACG TGGGCCCGGA CGGACGCAGC ATCCCGTGGG GGCGGCTGGA GCGCGCGGAC 
GCCGTGGACC TCGCGGAGCA GCTGGCCCAG TTCTACGGCC CGGAGCCTGC CCTGGAGGTG 
GCCCGCAAGA CCCTCAAGAG GGCGGACGCG CGCGACGTGG CGGCGCAGCT CCAGGAGCGG 
CGGCTGCAGC GGCTCGGGCT CGGCTCCGGG ACGCTGCTCT CCGTGTCCGA GTACAAGAAG 
AAGTACCGGG AGCACGTGCT GCAGCTGCAC GCTCGGGTGA AGGAGAGGAA CGCCCGCTCC 
GTGAAGATCA CCAAGCGCTT CACCAAGCTG CTCATCGCGC CCGAGAGCGC CGCCCCGGAG 
GAGGCGATGG GGCCCGCGGA AGAGCCTGAG CCGGGGCGCG CGCGGCGCTC GGACACGCAC 
ACTTTCAACC GCCTCTTCCG CCGCGACGAG GAGGGCCGGC GGCCGCTGAC CGTGGTGCTG 
CAGGGCCCGG CGGGCATCGG CAAGACCATG GCGGCCAAAA AGATCCTGTA CGACTGGGCG 
GCGGGCAAGC TGTACCAGGG CCAGGTGGAC TTCGCCTTCT TCATGCCCTG CGGCGAGCTG 
CTGGAGAGGC CGGGCACGCG CAGCCTGGCT GACCTGATCC TGGACCAGTG CCCCGACCGC 
GGCGCGCCGG TGCCGCAGAT GCTGGCCCAG CCGCAGCGGC TGCTCTTCAT CCTGGACGGC 
GCGGACGAGC TGCCGGCGCT GGGGGGCCCC GAGGCCGCGC CCTGCACAGA CCCCTTCGAG 
GCGGCGAGCG GCGCGCGGGT GCTAGGCGGG CTGCTGAGCA AGGCGCTGCT GCCCACGGCC 
CTCCTGCTGG TGACCACGCG CGCCGCCGCC CCCGGGAGGC TGCAGGGCCG CCTGTGTTCC 
CCGCAGTGCG CCGAGGTGCG CGGCTTCTCC GACAAGGACA AGAAGAAGTA TTTCTACAAG 
TATTTCCGGG ATGAGAGGAG GGCCGAGCGC GCCTACCGCT TCGTGAAGGA GAACGAGACG 
CTGTTCGCGC TGTGCTTCGT GCCCTTCGTG TGCTGGATCG TGTGCACCGT GCTGCGCCAG 
CAGCTGGAGC TCGGTCGGGA CCTGTCGCGC ACGTCCAAGA CCACCACGTC AGTGTACCTG 
CTTTTCATCA CCAGCGTTCT GAGCTCGGCT CCGGTAGCCG ACGGGCCCCG GTTGCAGGGC 
GACCTGCGCA ATCTGTGCCG CCTGGCCCGC GAGGGCGTCC TCGGACGCAG GGCGCAGTTT 
GCCGAGAAGG AACTGGAGCA ACTGGAGCTT CGTGGCTCCA AAGTGCAGAC GCTGTTTCTC 
AGCAAAAAGG AGCTGCCGGG CGTGCTGGAG ACAGAGGTCA CCTACCAGTT CATCGACCAG 
AGCTTCCAGG AGTTCCTCGC GGCACTGTCC TACCTGCTGG AGGACGGCGG GGTGCCCAGG 
ACCGCGGCTG GCGGCGTTGG GACACTCCTG CGTGGGGACG CCCAGCCGCA CAGCCACTTG 
GTGCTCACCA CGCGCTTCCT CTTCGGACTG CTGAGCGCGG AGCGGATGCG CGACATCGAG 
CGCCACTTCG GCTGCATGGT TTCAGAGCGT GTGAAGCAGG AGGCCCTGCG GTGGGTGCAG 
GGACAGGGAC AGGGCTGCCC CGGAGTGGCA CCAGAGGTGA CCGAGGGGGC CAAAGGGCTC 
GAGGACACCG AAGAGCCAGA GGAGGAGGAG GAGGGAGAGG AGCCCAACTA CCCACTGGAG 
TTGCTGTACT GCCTGTACGA GACGCAGGAG GACGCGTTTG TGCGCCAAGC CCTGTGCCGG 
TTCCCGGAGC TGGCGCTGCA GCGAGTGCGC TTCTGCCGCA TGGACGTGGC TGTTCTGAGC 
TACTGCGTGA GGTGCTGCCC TGCTGGACAG GCACTGCGGC TGATCAGCTG CAGATTGGTT 
GCTGCGCAGG AGAAGAAGAA GAAGAGCCTG GGGAAGCGGC TCCAGGCCAG CCTGGGTGGC 
GGCAGTTCTC AAGGCACCAC AAAACAACTG CCAGCCTCCC TTCTTCATCC ACTCTTTCAG 
GCAATGACTG ACCCACTGTG CCATCTGAGC AGCCTCACGC TGTCCCACTG CAAACTCCCT 
GACGCGGTCT GCCGAGACCT TTCTGAGGCC CTGAGGGCAG CCCCCGCACT GACGGAGCTG 
GGCCTCCTCC ACAACAGGCT CAGTGAGGCG GGACTGCGTA TGCTGAGTGA GGGCCTAGCC 
TGGCCGCAGT GCAGGGTGCA GACGGTCAGG GTACAGCTGC CTGACCCCCA GCGAGGGCTC 
CAGTACCTGG TGGGTATGCT TCGGCAGAGC CCTGCCCTGA CCACCCTGGA TCTCAGCGGC 
TGCCAACTGC CCGCCCCCAT GGTGACCTAC CTGTGTGCAG TCCTGCAGCA CCAGGGATGC 
GGCCTGCAGA CCCTCAGTCT GGCCTCTGTG GAGCTGAGCG AGCAGTCACT ACAGGAGCTT 
CAGGCTGTGA AGAGAGCAAA GCCGGATCTG GTCATCACAC ACCCAGCGCT GGACGGCCAC 
CCACAACCTC CCAAGGAACT CATCTCGACC TTCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001263629.1
CDS	164..2839
Translation	MDQPEAPCSSTGPRLAVARELLLAALEELSQEQLKRFRHKLRDVGPDGRSIPWGRLERADAVDLAEQLAQFYGPEPALEVARKTLKRADARDVAAQLQERRLQRLGLGSGTLLSVSEYKKKYREHVLQLHARVKERNARSVKITKRFTKLLIAPESAAPEEAMGPAEEPEPGRARRSDTHTFNRLFRRDEEGRRPLTVVLQGPAGIGKTMAAKKILYDWAAGKLYQGQVDFAFFMPCGELLERPGTRSLADLILDQCPDRGAPVPQMLAQPQRLLFILDGADELPALGGPEAAPCTDPFEAASGARVLGGLLSKALLPTALLLVTTRAAAPGRLQGRLCSPQCAEVRGFSDKDKKKYFYKYFRDERRAERAYRFVKENETLFALCFVPFVCWIVCTVLRQQLELGRDLSRTSKTTTSVYLLFITSVLSSAPVADGPRLQGDLRNLCRLAREGVLGRRAQFAEKELEQLELRGSKVQTLFLSKKELPGVLETEVTYQFIDQSFQEFLAALSYLLEDGGVPRTAAGGVGTLLRGDAQPHSHLVLTTRFLFGLLSAERMRDIERHFGCMVSERVKQEALRWVQGQGQGCPGVAPEVTEGAKGLEDTEEPEEEEEGEEPNYPLELLYCLYETQEDAFVRQALCRFPELALQRVRFCRMDVAVLSYCVRCCPAGQALRLISCRLVAAQEKKKKSLGKRLQASLGGGSSQGTTKQLPASLLHPLFQAMTDPLCHLSSLTLSHCKLPDAVCRDLSEALRAAPALTELGLLHNRLSEAGLRMLSEGLAWPQCRVQTVRVQLPDPQRGLQYLVGMLRQSPALTTLDLSGCQLPAPMVTYLCAVLQHQGCGLQTLSLASVELSEQSLQELQAVKRAKPDLVITHPALDGHPQPPKELISTF

Target ORF information:

RefSeq Version	NM_001276700.2
Organism	Homo sapiens(human)
Definition	Homo sapiens NLR family pyrin domain containing 6 (NLRP6), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001276700.2

ORF Insert Sequence:

ATGGACCAGC CAGAGGCCCC CTGCTCCAGC ACGGGGCCGC GCCTCGCGGT GGCCCGCGAG 
CTGCTCCTGG CTGCGCTGGA GGAACTGAGC CAAGAGCAGC TGAAGCGCTT CCGCCACAAG 
CTGCGCGACG TGGGCCCGGA CGGACGCAGC ATCCCGTGGG GGCGGCTGGA GCGCGCGGAC 
GCCGTGGACC TCGCGGAGCA GCTGGCCCAG TTCTACGGCC CGGAGCCTGC CCTGGAGGTG 
GCCCGCAAGA CCCTCAAGAG GGCGGACGCG CGCGACGTGG CGGCGCAGCT CCAGGAGCGG 
CGGCTGCAGC GGCTCGGGCT CGGCTCCGGG ACGCTGCTCT CCGTGTCCGA GTACAAGAAG 
AAGTACCGGG AGCACGTGCT GCAGCTGCAC GCTCGGGTGA AGGAGAGGAA CGCCCGCTCC 
GTGAAGATCA CCAAGCGCTT CACCAAGCTG CTCATCGCGC CCGAGAGCGC CGCCCCGGAG 
GAGGCGATGG GGCCCGCGGA AGAGCCTGAG CCGGGGCGCG CGCGGCGCTC GGACACGCAC 
ACTTTCAACC GCCTCTTCCG CCGCGACGAG GAGGGCCGGC GGCCGCTGAC CGTGGTGCTG 
CAGGGCCCGG CGGGCATCGG CAAGACCATG GCGGCCAAAA AGATCCTGTA CGACTGGGCG 
GCGGGCAAGC TGTACCAGGG CCAGGTGGAC TTCGCCTTCT TCATGCCCTG CGGCGAGCTG 
CTGGAGAGGC CGGGCACGCG CAGCCTGGCT GACCTGATCC TGGACCAGTG CCCCGACCGC 
GGCGCGCCGG TGCCGCAGAT GCTGGCCCAG CCGCAGCGGC TGCTCTTCAT CCTGGACGGC 
GCGGACGAGC TGCCGGCGCT GGGGGGCCCC GAGGCCGCGC CCTGCACAGA CCCCTTCGAG 
GCGGCGAGCG GCGCGCGGGT GCTAGGCGGG CTGCTGAGCA AGGCGCTGCT GCCCACGGCC 
CTCCTGCTGG TGACCACGCG CGCCGCCGCC CCCGGGAGGC TGCAGGGCCG CCTGTGTTCC 
CCGCAGTGCG CCGAGGTGCG CGGCTTCTCC GACAAGGACA AGAAGAAGTA TTTCTACAAG 
TATTTCCGGG ATGAGAGGAG GGCCGAGCGC GCCTACCGCT TCGTGAAGGA GAACGAGACG 
CTGTTCGCGC TGTGCTTCGT GCCCTTCGTG TGCTGGATCG TGTGCACCGT GCTGCGCCAG 
CAGCTGGAGC TCGGTCGGGA CCTGTCGCGC ACGTCCAAGA CCACCACGTC AGTGTACCTG 
CTTTTCATCA CCAGCGTTCT GAGCTCGGCT CCGGTAGCCG ACGGGCCCCG GTTGCAGGGC 
GACCTGCGCA ATCTGTGCCG CCTGGCCCGC GAGGGCGTCC TCGGACGCAG GGCGCAGTTT 
GCCGAGAAGG AACTGGAGCA ACTGGAGCTT CGTGGCTCCA AAGTGCAGAC GCTGTTTCTC 
AGCAAAAAGG AGCTGCCGGG CGTGCTGGAG ACAGAGGTCA CCTACCAGTT CATCGACCAG 
AGCTTCCAGG AGTTCCTCGC GGCACTGTCC TACCTGCTGG AGGACGGCGG GGTGCCCAGG 
ACCGCGGCTG GCGGCGTTGG GACACTCCTG CGTGGGGACG CCCAGCCGCA CAGCCACTTG 
GTGCTCACCA CGCGCTTCCT CTTCGGACTG CTGAGCGCGG AGCGGATGCG CGACATCGAG 
CGCCACTTCG GCTGCATGGT TTCAGAGCGT GTGAAGCAGG AGGCCCTGCG GTGGGTGCAG 
GGACAGGGAC AGGGCTGCCC CGGAGTGGCA CCAGAGGTGA CCGAGGGGGC CAAAGGGCTC 
GAGGACACCG AAGAGCCAGA GGAGGAGGAG GAGGGAGAGG AGCCCAACTA CCCACTGGAG 
TTGCTGTACT GCCTGTACGA GACGCAGGAG GACGCGTTTG TGCGCCAAGC CCTGTGCCGG 
TTCCCGGAGC TGGCGCTGCA GCGAGTGCGC TTCTGCCGCA TGGACGTGGC TGTTCTGAGC 
TACTGCGTGA GGTGCTGCCC TGCTGGACAG GCACTGCGGC TGATCAGCTG CAGATTGGTT 
GCTGCGCAGG AGAAGAAGAA GAAGAGCCTG GGGAAGCGGC TCCAGGCCAG CCTGGGTGGC 
GGCAGTTCTC AAGGCACCAC AAAACAACTG CCAGCCTCCC TTCTTCATCC ACTCTTTCAG 
GCAATGACTG ACCCACTGTG CCATCTGAGC AGCCTCACGC TGTCCCACTG CAAACTCCCT 
GACGCGGTCT GCCGAGACCT TTCTGAGGCC CTGAGGGCAG CCCCCGCACT GACGGAGCTG 
GGCCTCCTCC ACAACAGGCT CAGTGAGGCG GGACTGCGTA TGCTGAGTGA GGGCCTAGCC 
TGGCCGCAGT GCAGGGTGCA GACGGTCAGG GTACAGCTGC CTGACCCCCA GCGAGGGCTC 
CAGTACCTGG TGGGTATGCT TCGGCAGAGC CCTGCCCTGA CCACCCTGGA TCTCAGCGGC 
TGCCAACTGC CCGCCCCCAT GGTGACCTAC CTGTGTGCAG TCCTGCAGCA CCAGGGATGC 
GGCCTGCAGA CCCTCAGTCT GGCCTCTGTG GAGCTGAGCG AGCAGTCACT ACAGGAGCTT 
CAGGCTGTGA AGAGAGCAAA GCCGGATCTG GTCATCACAC ACCCAGCGCT GGACGGCCAC 
CCACAACCTC CCAAGGAACT CATCTCGACC TTCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

NLRP6 ( NM_001276700.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001263629.1 Homo sapiens NLR family pyrin domain containing 6 (NLRP6), transcript variant 2, mRNA.

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CloneID	OHu20628
Clone ID Related Accession (Same CDS sequence)	NM_001276700.2 , NM_001276700.1
Accession Version	NM_001276700.1	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2676bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2018-06-24
Organism	Homo sapiens(human)
Product	NACHT, LRR and PYD domains-containing protein 6 isoform 2
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AF479748.1, AC136475.7, AK292668.1 and CD636365.1. Transcript Variant: This variant (2) uses an alternate in-frame exon at the 5' end of an exon compared to variant 1. The resulting isoform (2) lacks a single internal aa compared to isoform 1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK292668.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2144835, SAMEA2152474 [ECO:0000348] ##Evidence-Data-END##

ATGGACCAGC CAGAGGCCCC CTGCTCCAGC ACGGGGCCGC GCCTCGCGGT GGCCCGCGAG 
CTGCTCCTGG CTGCGCTGGA GGAACTGAGC CAAGAGCAGC TGAAGCGCTT CCGCCACAAG 
CTGCGCGACG TGGGCCCGGA CGGACGCAGC ATCCCGTGGG GGCGGCTGGA GCGCGCGGAC 
GCCGTGGACC TCGCGGAGCA GCTGGCCCAG TTCTACGGCC CGGAGCCTGC CCTGGAGGTG 
GCCCGCAAGA CCCTCAAGAG GGCGGACGCG CGCGACGTGG CGGCGCAGCT CCAGGAGCGG 
CGGCTGCAGC GGCTCGGGCT CGGCTCCGGG ACGCTGCTCT CCGTGTCCGA GTACAAGAAG 
AAGTACCGGG AGCACGTGCT GCAGCTGCAC GCTCGGGTGA AGGAGAGGAA CGCCCGCTCC 
GTGAAGATCA CCAAGCGCTT CACCAAGCTG CTCATCGCGC CCGAGAGCGC CGCCCCGGAG 
GAGGCGATGG GGCCCGCGGA AGAGCCTGAG CCGGGGCGCG CGCGGCGCTC GGACACGCAC 
ACTTTCAACC GCCTCTTCCG CCGCGACGAG GAGGGCCGGC GGCCGCTGAC CGTGGTGCTG 
CAGGGCCCGG CGGGCATCGG CAAGACCATG GCGGCCAAAA AGATCCTGTA CGACTGGGCG 
GCGGGCAAGC TGTACCAGGG CCAGGTGGAC TTCGCCTTCT TCATGCCCTG CGGCGAGCTG 
CTGGAGAGGC CGGGCACGCG CAGCCTGGCT GACCTGATCC TGGACCAGTG CCCCGACCGC 
GGCGCGCCGG TGCCGCAGAT GCTGGCCCAG CCGCAGCGGC TGCTCTTCAT CCTGGACGGC 
GCGGACGAGC TGCCGGCGCT GGGGGGCCCC GAGGCCGCGC CCTGCACAGA CCCCTTCGAG 
GCGGCGAGCG GCGCGCGGGT GCTAGGCGGG CTGCTGAGCA AGGCGCTGCT GCCCACGGCC 
CTCCTGCTGG TGACCACGCG CGCCGCCGCC CCCGGGAGGC TGCAGGGCCG CCTGTGTTCC 
CCGCAGTGCG CCGAGGTGCG CGGCTTCTCC GACAAGGACA AGAAGAAGTA TTTCTACAAG 
TATTTCCGGG ATGAGAGGAG GGCCGAGCGC GCCTACCGCT TCGTGAAGGA GAACGAGACG 
CTGTTCGCGC TGTGCTTCGT GCCCTTCGTG TGCTGGATCG TGTGCACCGT GCTGCGCCAG 
CAGCTGGAGC TCGGTCGGGA CCTGTCGCGC ACGTCCAAGA CCACCACGTC AGTGTACCTG 
CTTTTCATCA CCAGCGTTCT GAGCTCGGCT CCGGTAGCCG ACGGGCCCCG GTTGCAGGGC 
GACCTGCGCA ATCTGTGCCG CCTGGCCCGC GAGGGCGTCC TCGGACGCAG GGCGCAGTTT 
GCCGAGAAGG AACTGGAGCA ACTGGAGCTT CGTGGCTCCA AAGTGCAGAC GCTGTTTCTC 
AGCAAAAAGG AGCTGCCGGG CGTGCTGGAG ACAGAGGTCA CCTACCAGTT CATCGACCAG 
AGCTTCCAGG AGTTCCTCGC GGCACTGTCC TACCTGCTGG AGGACGGCGG GGTGCCCAGG 
ACCGCGGCTG GCGGCGTTGG GACACTCCTG CGTGGGGACG CCCAGCCGCA CAGCCACTTG 
GTGCTCACCA CGCGCTTCCT CTTCGGACTG CTGAGCGCGG AGCGGATGCG CGACATCGAG 
CGCCACTTCG GCTGCATGGT TTCAGAGCGT GTGAAGCAGG AGGCCCTGCG GTGGGTGCAG 
GGACAGGGAC AGGGCTGCCC CGGAGTGGCA CCAGAGGTGA CCGAGGGGGC CAAAGGGCTC 
GAGGACACCG AAGAGCCAGA GGAGGAGGAG GAGGGAGAGG AGCCCAACTA CCCACTGGAG 
TTGCTGTACT GCCTGTACGA GACGCAGGAG GACGCGTTTG TGCGCCAAGC CCTGTGCCGG 
TTCCCGGAGC TGGCGCTGCA GCGAGTGCGC TTCTGCCGCA TGGACGTGGC TGTTCTGAGC 
TACTGCGTGA GGTGCTGCCC TGCTGGACAG GCACTGCGGC TGATCAGCTG CAGATTGGTT 
GCTGCGCAGG AGAAGAAGAA GAAGAGCCTG GGGAAGCGGC TCCAGGCCAG CCTGGGTGGC 
GGCAGTTCTC AAGGCACCAC AAAACAACTG CCAGCCTCCC TTCTTCATCC ACTCTTTCAG 
GCAATGACTG ACCCACTGTG CCATCTGAGC AGCCTCACGC TGTCCCACTG CAAACTCCCT 
GACGCGGTCT GCCGAGACCT TTCTGAGGCC CTGAGGGCAG CCCCCGCACT GACGGAGCTG 
GGCCTCCTCC ACAACAGGCT CAGTGAGGCG GGACTGCGTA TGCTGAGTGA GGGCCTAGCC 
TGGCCGCAGT GCAGGGTGCA GACGGTCAGG GTACAGCTGC CTGACCCCCA GCGAGGGCTC 
CAGTACCTGG TGGGTATGCT TCGGCAGAGC CCTGCCCTGA CCACCCTGGA TCTCAGCGGC 
TGCCAACTGC CCGCCCCCAT GGTGACCTAC CTGTGTGCAG TCCTGCAGCA CCAGGGATGC 
GGCCTGCAGA CCCTCAGTCT GGCCTCTGTG GAGCTGAGCG AGCAGTCACT ACAGGAGCTT 
CAGGCTGTGA AGAGAGCAAA GCCGGATCTG GTCATCACAC ACCCAGCGCT GGACGGCCAC 
CCACAACCTC CCAAGGAACT CATCTCGACC TTCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001263629.1
CDS	1..2676
Translation	MDQPEAPCSSTGPRLAVARELLLAALEELSQEQLKRFRHKLRDVGPDGRSIPWGRLERADAVDLAEQLAQFYGPEPALEVARKTLKRADARDVAAQLQERRLQRLGLGSGTLLSVSEYKKKYREHVLQLHARVKERNARSVKITKRFTKLLIAPESAAPEEAMGPAEEPEPGRARRSDTHTFNRLFRRDEEGRRPLTVVLQGPAGIGKTMAAKKILYDWAAGKLYQGQVDFAFFMPCGELLERPGTRSLADLILDQCPDRGAPVPQMLAQPQRLLFILDGADELPALGGPEAAPCTDPFEAASGARVLGGLLSKALLPTALLLVTTRAAAPGRLQGRLCSPQCAEVRGFSDKDKKKYFYKYFRDERRAERAYRFVKENETLFALCFVPFVCWIVCTVLRQQLELGRDLSRTSKTTTSVYLLFITSVLSSAPVADGPRLQGDLRNLCRLAREGVLGRRAQFAEKELEQLELRGSKVQTLFLSKKELPGVLETEVTYQFIDQSFQEFLAALSYLLEDGGVPRTAAGGVGTLLRGDAQPHSHLVLTTRFLFGLLSAERMRDIERHFGCMVSERVKQEALRWVQGQGQGCPGVAPEVTEGAKGLEDTEEPEEEEEGEEPNYPLELLYCLYETQEDAFVRQALCRFPELALQRVRFCRMDVAVLSYCVRCCPAGQALRLISCRLVAAQEKKKKSLGKRLQASLGGGSSQGTTKQLPASLLHPLFQAMTDPLCHLSSLTLSHCKLPDAVCRDLSEALRAAPALTELGLLHNRLSEAGLRMLSEGLAWPQCRVQTVRVQLPDPQRGLQYLVGMLRQSPALTTLDLSGCQLPAPMVTYLCAVLQHQGCGLQTLSLASVELSEQSLQELQAVKRAKPDLVITHPALDGHPQPPKELISTF

Target ORF information:

RefSeq Version	NM_001276700.1
Organism	Homo sapiens(human)
Definition	Homo sapiens NLR family pyrin domain containing 6 (NLRP6), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001276700.1

ORF Insert Sequence:

ATGGACCAGC CAGAGGCCCC CTGCTCCAGC ACGGGGCCGC GCCTCGCGGT GGCCCGCGAG 
CTGCTCCTGG CTGCGCTGGA GGAACTGAGC CAAGAGCAGC TGAAGCGCTT CCGCCACAAG 
CTGCGCGACG TGGGCCCGGA CGGACGCAGC ATCCCGTGGG GGCGGCTGGA GCGCGCGGAC 
GCCGTGGACC TCGCGGAGCA GCTGGCCCAG TTCTACGGCC CGGAGCCTGC CCTGGAGGTG 
GCCCGCAAGA CCCTCAAGAG GGCGGACGCG CGCGACGTGG CGGCGCAGCT CCAGGAGCGG 
CGGCTGCAGC GGCTCGGGCT CGGCTCCGGG ACGCTGCTCT CCGTGTCCGA GTACAAGAAG 
AAGTACCGGG AGCACGTGCT GCAGCTGCAC GCTCGGGTGA AGGAGAGGAA CGCCCGCTCC 
GTGAAGATCA CCAAGCGCTT CACCAAGCTG CTCATCGCGC CCGAGAGCGC CGCCCCGGAG 
GAGGCGATGG GGCCCGCGGA AGAGCCTGAG CCGGGGCGCG CGCGGCGCTC GGACACGCAC 
ACTTTCAACC GCCTCTTCCG CCGCGACGAG GAGGGCCGGC GGCCGCTGAC CGTGGTGCTG 
CAGGGCCCGG CGGGCATCGG CAAGACCATG GCGGCCAAAA AGATCCTGTA CGACTGGGCG 
GCGGGCAAGC TGTACCAGGG CCAGGTGGAC TTCGCCTTCT TCATGCCCTG CGGCGAGCTG 
CTGGAGAGGC CGGGCACGCG CAGCCTGGCT GACCTGATCC TGGACCAGTG CCCCGACCGC 
GGCGCGCCGG TGCCGCAGAT GCTGGCCCAG CCGCAGCGGC TGCTCTTCAT CCTGGACGGC 
GCGGACGAGC TGCCGGCGCT GGGGGGCCCC GAGGCCGCGC CCTGCACAGA CCCCTTCGAG 
GCGGCGAGCG GCGCGCGGGT GCTAGGCGGG CTGCTGAGCA AGGCGCTGCT GCCCACGGCC 
CTCCTGCTGG TGACCACGCG CGCCGCCGCC CCCGGGAGGC TGCAGGGCCG CCTGTGTTCC 
CCGCAGTGCG CCGAGGTGCG CGGCTTCTCC GACAAGGACA AGAAGAAGTA TTTCTACAAG 
TATTTCCGGG ATGAGAGGAG GGCCGAGCGC GCCTACCGCT TCGTGAAGGA GAACGAGACG 
CTGTTCGCGC TGTGCTTCGT GCCCTTCGTG TGCTGGATCG TGTGCACCGT GCTGCGCCAG 
CAGCTGGAGC TCGGTCGGGA CCTGTCGCGC ACGTCCAAGA CCACCACGTC AGTGTACCTG 
CTTTTCATCA CCAGCGTTCT GAGCTCGGCT CCGGTAGCCG ACGGGCCCCG GTTGCAGGGC 
GACCTGCGCA ATCTGTGCCG CCTGGCCCGC GAGGGCGTCC TCGGACGCAG GGCGCAGTTT 
GCCGAGAAGG AACTGGAGCA ACTGGAGCTT CGTGGCTCCA AAGTGCAGAC GCTGTTTCTC 
AGCAAAAAGG AGCTGCCGGG CGTGCTGGAG ACAGAGGTCA CCTACCAGTT CATCGACCAG 
AGCTTCCAGG AGTTCCTCGC GGCACTGTCC TACCTGCTGG AGGACGGCGG GGTGCCCAGG 
ACCGCGGCTG GCGGCGTTGG GACACTCCTG CGTGGGGACG CCCAGCCGCA CAGCCACTTG 
GTGCTCACCA CGCGCTTCCT CTTCGGACTG CTGAGCGCGG AGCGGATGCG CGACATCGAG 
CGCCACTTCG GCTGCATGGT TTCAGAGCGT GTGAAGCAGG AGGCCCTGCG GTGGGTGCAG 
GGACAGGGAC AGGGCTGCCC CGGAGTGGCA CCAGAGGTGA CCGAGGGGGC CAAAGGGCTC 
GAGGACACCG AAGAGCCAGA GGAGGAGGAG GAGGGAGAGG AGCCCAACTA CCCACTGGAG 
TTGCTGTACT GCCTGTACGA GACGCAGGAG GACGCGTTTG TGCGCCAAGC CCTGTGCCGG 
TTCCCGGAGC TGGCGCTGCA GCGAGTGCGC TTCTGCCGCA TGGACGTGGC TGTTCTGAGC 
TACTGCGTGA GGTGCTGCCC TGCTGGACAG GCACTGCGGC TGATCAGCTG CAGATTGGTT 
GCTGCGCAGG AGAAGAAGAA GAAGAGCCTG GGGAAGCGGC TCCAGGCCAG CCTGGGTGGC 
GGCAGTTCTC AAGGCACCAC AAAACAACTG CCAGCCTCCC TTCTTCATCC ACTCTTTCAG 
GCAATGACTG ACCCACTGTG CCATCTGAGC AGCCTCACGC TGTCCCACTG CAAACTCCCT 
GACGCGGTCT GCCGAGACCT TTCTGAGGCC CTGAGGGCAG CCCCCGCACT GACGGAGCTG 
GGCCTCCTCC ACAACAGGCT CAGTGAGGCG GGACTGCGTA TGCTGAGTGA GGGCCTAGCC 
TGGCCGCAGT GCAGGGTGCA GACGGTCAGG GTACAGCTGC CTGACCCCCA GCGAGGGCTC 
CAGTACCTGG TGGGTATGCT TCGGCAGAGC CCTGCCCTGA CCACCCTGGA TCTCAGCGGC 
TGCCAACTGC CCGCCCCCAT GGTGACCTAC CTGTGTGCAG TCCTGCAGCA CCAGGGATGC 
GGCCTGCAGA CCCTCAGTCT GGCCTCTGTG GAGCTGAGCG AGCAGTCACT ACAGGAGCTT 
CAGGCTGTGA AGAGAGCAAA GCCGGATCTG GTCATCACAC ACCCAGCGCT GGACGGCCAC 
CCACAACCTC CCAAGGAACT CATCTCGACC TTCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

NLRP6 ( XM_011519931.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_011518233.1 Homo sapiens NLR family, pyrin domain containing 6 (NLRP6), transcript variant X4, mRNA.

Price & Availability↑

CloneID	OHu77447
Clone ID Related Accession (Same CDS sequence)	XM_011519931.1
Accession Version	XM_011519931.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2112bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-06-05
Organism	Homo sapiens(human)
Product	NACHT, LRR and PYD domains-containing protein 6 isoform X3
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000011.10) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGACCAGC CAGAGGCCCC CTGCTCCAGC ACGGGGCCGC GCCTCGCGGT GGCCCGCGAG 
CTGCTCCTGG CTGCGCTGGA GGAACTGAGC CAAGAGCAGC TGAAGCGCTT CCGCCACAAG 
CTGCGCGACG TGGGCCCGGA CGGACGCAGC ATCCCGTGGG GGCGGCTGGA GCGCGCGGAC 
GCCGTGGACC TCGCGGAGCA GCTGGCCCAG TTCTACGGCC CGGAGCCTGC CCTGGAGGTG 
GCCCGCAAGA CCCTCAAGAG GGCGGACGCG CGCGACGTGG CGGCGCAGCT CCAGGAGCGG 
CGGCTGCAGC GGCTCGGGCT CGGCTCCGGG ACGCTGCTCT CCGTGTCCGA GTACAAGAAG 
AAGTACCGGG AGCACGTGCT GCAGCTGCAC GCTCGGGTGA AGGAGAGGAA CGCCCGCTCC 
GTGAAGATCA CCAAGCGCTT CACCAAGCTG CTCATCGCGC CCGAGAGCGC CGCCCCGGAG 
GAGGCGATGG GGCCCGCGGA AGAGCCTGAG CCGGGGCGCG CGCGGCGCTC GGACACGCAC 
ACTTTCAACC GCCTCTTCCG CCGCGACGAG GAGGGCCGGC GGCCGCTGAC CGTGGTGCTG 
CAGGGCCCGG CGGGCATCGG CAAGACCATG GCGGCCAAAA AGATCCTGTA CGACTGGGCG 
GCGGGCAAGC TGTACCAGGG CCAGGTGGAC TTCGCCTTCT TCATGCCCTG CGGCGAGCTG 
CTGGAGAGGC CGGGCACGCG CAGCCTGGCT GACCTGATCC TGGACCAGTG CCCCGACCGC 
GGCGCGCCGG TGCCGCAGAT GCTGGCCCAG CCGCAGCGGC TGCTCTTCAT CCTGGACGGC 
GCGGACGAGC TGCCGGCGCT GGGGGGCCCC GAGGCCGCGC CCTGCACAGA CCCCTTCGAG 
GCGGCGAGCG GCGCGCGGGT GCTAGGCGGG CTGCTGAGCA AGGCGCTGCT GCCCACGGCC 
CTCCTGCTGG TGACCACGCG CGCCGCCGCC CCCGGGAGGC TGCAGGGCCG CCTGTGTTCC 
CCGCAGTGCG CCGAGGTGCG CGGCTTCTCC GACAAGGACA AGAAGAAGTA TTTCTACAAG 
TATTTCCGGG ATGAGAGGAG GGCCGAGCGC GCCTACCGCT TCGTGAAGGA GAACGAGACG 
CTGTTCGCGC TGTGCTTCGT GCCCTTCGTG TGCTGGATCG TGTGCACCGT GCTGCGCCAG 
CAGCTGGAGC TCGGTCGGGA CCTGTCGCGC ACGTCCAAGA CCACCACGTC AGTGTACCTG 
CTTTTCATCA CCAGCGTTCT GAGCTCGGCT CCGGTAGCCG ACGGGCCCCG GTTGCAGGGC 
GACCTGCGCA ATCTGTGCCG CCTGGCCCGC GAGGGCGTCC TCGGACGCAG GGCGCAGTTT 
GCCGAGAAGG AACTGGAGCA ACTGGAGCTT CGTGGCTCCA AAGTGCAGAC GCTGTTTCTC 
AGCAAAAAGG AGCTGCCGGG CGTGCTGGAG ACAGAGGTCA CCTACCAGTT CATCGACCAG 
AGCTTCCAGG AGTTCCTCGC GGCACTGTCC TACCTGCTGG AGGACGGCGG GGTGCCCAGG 
ACCGCGGCTG GCGGCGTTGG GACACTCCTG CGTGGGGACG CCCAGCCGCA CAGCCACTTG 
GTGCTCACCA CGCGCTTCCT CTTCGGACTG CTGAGCGCGG AGCGGATGCG CGACATCGAG 
CGCCACTTCG GCTGCATGGT TTCAGAGCGT GTGAAGCAGG AGGCCCTGCG GTGGGTGCAG 
GGACAGGGAC AGGGCTGCCC CGGAGTGGCA CCAGAGGTGA CCGAGGGGGC CAAAGGGCTC 
GAGGACACCG AAGAGCCAGA GGAGGAGGAG GAGGGAGAGG AGCCCAACTA CCCACTGGAG 
TTGCTGTACT GCCTGTACGA GACGCAGGAG GACGCGTTTG TGCGCCAAGC CCTGTGCCGG 
TTCCCGGAGC TGGCGCTGCA GCGAGTGCGC TTCTGCCGCA TGGACGTGGC TGTTCTGAGC 
TACTGCGTGA GGTGCTGCCC TGCTGGACAG GCACTGCGGC TGATCAGCTG CAGATTGGTT 
GCTGCGCAGG AGAAGAAGAA GAAGAGCCTG GGGAAGCGGC TCCAGGCCAG CCTGGGTGGC 
GGCAGGCAAT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_011518233.1
CDS	206..2317
Translation	MDQPEAPCSSTGPRLAVARELLLAALEELSQEQLKRFRHKLRDVGPDGRSIPWGRLERADAVDLAEQLAQFYGPEPALEVARKTLKRADARDVAAQLQERRLQRLGLGSGTLLSVSEYKKKYREHVLQLHARVKERNARSVKITKRFTKLLIAPESAAPEEAMGPAEEPEPGRARRSDTHTFNRLFRRDEEGRRPLTVVLQGPAGIGKTMAAKKILYDWAAGKLYQGQVDFAFFMPCGELLERPGTRSLADLILDQCPDRGAPVPQMLAQPQRLLFILDGADELPALGGPEAAPCTDPFEAASGARVLGGLLSKALLPTALLLVTTRAAAPGRLQGRLCSPQCAEVRGFSDKDKKKYFYKYFRDERRAERAYRFVKENETLFALCFVPFVCWIVCTVLRQQLELGRDLSRTSKTTTSVYLLFITSVLSSAPVADGPRLQGDLRNLCRLAREGVLGRRAQFAEKELEQLELRGSKVQTLFLSKKELPGVLETEVTYQFIDQSFQEFLAALSYLLEDGGVPRTAAGGVGTLLRGDAQPHSHLVLTTRFLFGLLSAERMRDIERHFGCMVSERVKQEALRWVQGQGQGCPGVAPEVTEGAKGLEDTEEPEEEEEGEEPNYPLELLYCLYETQEDAFVRQALCRFPELALQRVRFCRMDVAVLSYCVRCCPAGQALRLISCRLVAAQEKKKKSLGKRLQASLGGGRQ

Target ORF information:

RefSeq Version	XM_011519931.1
Organism	Homo sapiens(human)
Definition	Homo sapiens NLR family, pyrin domain containing 6 (NLRP6), transcript variant X4, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011519931.1

ORF Insert Sequence:

ATGGACCAGC CAGAGGCCCC CTGCTCCAGC ACGGGGCCGC GCCTCGCGGT GGCCCGCGAG 
CTGCTCCTGG CTGCGCTGGA GGAACTGAGC CAAGAGCAGC TGAAGCGCTT CCGCCACAAG 
CTGCGCGACG TGGGCCCGGA CGGACGCAGC ATCCCGTGGG GGCGGCTGGA GCGCGCGGAC 
GCCGTGGACC TCGCGGAGCA GCTGGCCCAG TTCTACGGCC CGGAGCCTGC CCTGGAGGTG 
GCCCGCAAGA CCCTCAAGAG GGCGGACGCG CGCGACGTGG CGGCGCAGCT CCAGGAGCGG 
CGGCTGCAGC GGCTCGGGCT CGGCTCCGGG ACGCTGCTCT CCGTGTCCGA GTACAAGAAG 
AAGTACCGGG AGCACGTGCT GCAGCTGCAC GCTCGGGTGA AGGAGAGGAA CGCCCGCTCC 
GTGAAGATCA CCAAGCGCTT CACCAAGCTG CTCATCGCGC CCGAGAGCGC CGCCCCGGAG 
GAGGCGATGG GGCCCGCGGA AGAGCCTGAG CCGGGGCGCG CGCGGCGCTC GGACACGCAC 
ACTTTCAACC GCCTCTTCCG CCGCGACGAG GAGGGCCGGC GGCCGCTGAC CGTGGTGCTG 
CAGGGCCCGG CGGGCATCGG CAAGACCATG GCGGCCAAAA AGATCCTGTA CGACTGGGCG 
GCGGGCAAGC TGTACCAGGG CCAGGTGGAC TTCGCCTTCT TCATGCCCTG CGGCGAGCTG 
CTGGAGAGGC CGGGCACGCG CAGCCTGGCT GACCTGATCC TGGACCAGTG CCCCGACCGC 
GGCGCGCCGG TGCCGCAGAT GCTGGCCCAG CCGCAGCGGC TGCTCTTCAT CCTGGACGGC 
GCGGACGAGC TGCCGGCGCT GGGGGGCCCC GAGGCCGCGC CCTGCACAGA CCCCTTCGAG 
GCGGCGAGCG GCGCGCGGGT GCTAGGCGGG CTGCTGAGCA AGGCGCTGCT GCCCACGGCC 
CTCCTGCTGG TGACCACGCG CGCCGCCGCC CCCGGGAGGC TGCAGGGCCG CCTGTGTTCC 
CCGCAGTGCG CCGAGGTGCG CGGCTTCTCC GACAAGGACA AGAAGAAGTA TTTCTACAAG 
TATTTCCGGG ATGAGAGGAG GGCCGAGCGC GCCTACCGCT TCGTGAAGGA GAACGAGACG 
CTGTTCGCGC TGTGCTTCGT GCCCTTCGTG TGCTGGATCG TGTGCACCGT GCTGCGCCAG 
CAGCTGGAGC TCGGTCGGGA CCTGTCGCGC ACGTCCAAGA CCACCACGTC AGTGTACCTG 
CTTTTCATCA CCAGCGTTCT GAGCTCGGCT CCGGTAGCCG ACGGGCCCCG GTTGCAGGGC 
GACCTGCGCA ATCTGTGCCG CCTGGCCCGC GAGGGCGTCC TCGGACGCAG GGCGCAGTTT 
GCCGAGAAGG AACTGGAGCA ACTGGAGCTT CGTGGCTCCA AAGTGCAGAC GCTGTTTCTC 
AGCAAAAAGG AGCTGCCGGG CGTGCTGGAG ACAGAGGTCA CCTACCAGTT CATCGACCAG 
AGCTTCCAGG AGTTCCTCGC GGCACTGTCC TACCTGCTGG AGGACGGCGG GGTGCCCAGG 
ACCGCGGCTG GCGGCGTTGG GACACTCCTG CGTGGGGACG CCCAGCCGCA CAGCCACTTG 
GTGCTCACCA CGCGCTTCCT CTTCGGACTG CTGAGCGCGG AGCGGATGCG CGACATCGAG 
CGCCACTTCG GCTGCATGGT TTCAGAGCGT GTGAAGCAGG AGGCCCTGCG GTGGGTGCAG 
GGACAGGGAC AGGGCTGCCC CGGAGTGGCA CCAGAGGTGA CCGAGGGGGC CAAAGGGCTC 
GAGGACACCG AAGAGCCAGA GGAGGAGGAG GAGGGAGAGG AGCCCAACTA CCCACTGGAG 
TTGCTGTACT GCCTGTACGA GACGCAGGAG GACGCGTTTG TGCGCCAAGC CCTGTGCCGG 
TTCCCGGAGC TGGCGCTGCA GCGAGTGCGC TTCTGCCGCA TGGACGTGGC TGTTCTGAGC 
TACTGCGTGA GGTGCTGCCC TGCTGGACAG GCACTGCGGC TGATCAGCTG CAGATTGGTT 
GCTGCGCAGG AGAAGAAGAA GAAGAGCCTG GGGAAGCGGC TCCAGGCCAG CCTGGGTGGC 
GGCAGGCAAT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

NLRP6 ( XM_017017252.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_016872741.1 Homo sapiens NLR family, pyrin domain containing 6 (NLRP6), transcript variant X1, mRNA.

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CloneID	OHu91969
Clone ID Related Accession (Same CDS sequence)	XM_017017252.1
Accession Version	XM_017017252.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2316bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-06-05
Organism	Homo sapiens(human)
Product	NACHT, LRR and PYD domains-containing protein 6 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000011.10) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGACCAGC CAGAGGCCCC CTGCTCCAGC ACGGGGCCGC GCCTCGCGGT GGCCCGCGAG 
CTGCTCCTGG CTGCGCTGGA GGAACTGAGC CAAGAGCAGC TGAAGCGCTT CCGCCACAAG 
CTGCGCGACG TGGGCCCGGA CGGACGCAGC ATCCCGTGGG GGCGGCTGGA GCGCGCGGAC 
GCCGTGGACC TCGCGGAGCA GCTGGCCCAG TTCTACGGCC CGGAGCCTGC CCTGGAGGTG 
GCCCGCAAGA CCCTCAAGAG GGCGGACGCG CGCGACGTGG CGGCGCAGCT CCAGGAGCGG 
CGGCTGCAGC GGCTCGGGCT CGGCTCCGGG ACGCTGCTCT CCGTGTCCGA GTACAAGAAG 
AAGTACCGGG AGCACGTGCT GCAGCTGCAC GCTCGGGTGA AGGAGAGGAA CGCCCGCTCC 
GTGAAGATCA CCAAGCGCTT CACCAAGCTG CTCATCGCGC CCGAGAGCGC CGCCCCGGAG 
GAGGCGATGG GGCCCGCGGA AGAGCCTGAG CCGGGGCGCG CGCGGCGCTC GGACACGCAC 
ACTTTCAACC GCCTCTTCCG CCGCGACGAG GAGGGCCGGC GGCCGCTGAC CGTGGTGCTG 
CAGGGCCCGG CGGGCATCGG CAAGACCATG GCGGCCAAAA AGATCCTGTA CGACTGGGCG 
GCGGGCAAGC TGTACCAGGG CCAGGTGGAC TTCGCCTTCT TCATGCCCTG CGGCGAGCTG 
CTGGAGAGGC CGGGCACGCG CAGCCTGGCT GACCTGATCC TGGACCAGTG CCCCGACCGC 
GGCGCGCCGG TGCCGCAGAT GCTGGCCCAG CCGCAGCGGC TGCTCTTCAT CCTGGACGGC 
GCGGACGAGC TGCCGGCGCT GGGGGGCCCC GAGGCCGCGC CCTGCACAGA CCCCTTCGAG 
GCGGCGAGCG GCGCGCGGGT GCTAGGCGGG CTGCTGAGCA AGGCGCTGCT GCCCACGGCC 
CTCCTGCTGG TGACCACGCG CGCCGCCGCC CCCGGGAGGC TGCAGGGCCG CCTGTGTTCC 
CCGCAGTGCG CCGAGGTGCG CGGCTTCTCC GACAAGGACA AGAAGAAGTA TTTCTACAAG 
TATTTCCGGG ATGAGAGGAG GGCCGAGCGC GCCTACCGCT TCGTGAAGGA GAACGAGACG 
CTGTTCGCGC TGTGCTTCGT GCCCTTCGTG TGCTGGATCG TGTGCACCGT GCTGCGCCAG 
CAGCTGGAGC TCGGTCGGGA CCTGTCGCGC ACGTCCAAGA CCACCACGTC AGTGTACCTG 
CTTTTCATCA CCAGCGTTCT GAGCTCGGCT CCGGTAGCCG ACGGGCCCCG GTTGCAGGGC 
GACCTGCGCA ATCTGTGCCG CCTGGCCCGC GAGGGCGTCC TCGGACGCAG GGCGCAGTTT 
GCCGAGAAGG AACTGGAGCA ACTGGAGCTT CGTGGCTCCA AAGTGCAGAC GCTGTTTCTC 
AGCAAAAAGG AGCTGCCGGG CGTGCTGGAG ACAGAGGTCA CCTACCAGTT CATCGACCAG 
AGCTTCCAGG AGTTCCTCGC GGCACTGTCC TACCTGCTGG AGGACGGCGG GGTGCCCAGG 
ACCGCGGCTG GCGGCGTTGG GACACTCCTG CGTGGGGACG CCCAGCCGCA CAGCCACTTG 
GTGCTCACCA CGCGCTTCCT CTTCGGACTG CTGAGCGCGG AGCGGATGCG CGACATCGAG 
CGCCACTTCG GCTGCATGGT TTCAGAGCGT GTGAAGCAGG AGGCCCTGCG GTGGGTGCAG 
GGACAGGGAC AGGGCTGCCC CGGAGTGGCA CCAGAGGTGA CCGAGGGGGC CAAAGGGCTC 
GAGGACACCG AAGAGCCAGA GGAGGAGGAG GAGGGAGAGG AGCCCAACTA CCCACTGGAG 
TTGCTGTACT GCCTGTACGA GACGCAGGAG GACGCGTTTG TGCGCCAAGC CCTGTGCCGG 
TTCCCGGAGC TGGCGCTGCA GCGAGTGCGC TTCTGCCGCA TGGACGTGGC TGTTCTGAGC 
TACTGCGTGA GGTGCTGCCC TGCTGGACAG GCACTGCGGC TGATCAGCTG CAGATTGGTT 
GCTGCGCAGG AGAAGAAGAA GAAGAGCCTG GGGAAGCGGC TCCAGGCCAG CCTGGGTGGC 
GGCAGCAGTT CTCAAGGCAC CACAAAACAA CTGCCAGCCT CCCTTCTTCA TCCACTCTTT 
CAGGCAATGA CTGACCCACT GTGCCATCTG AGCAGCCTCA CGGAGGCTGC CGTTGGAAAC 
TGCTGGGTTC TCAGAAGCAG TGGAGGAAGG TGTTCAAGCG CAGGCTCCAA GGTCAGGCTG 
TCTGCAAATG CTAGCCGGCT TCTGCGTGCC CAGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_016872741.1
CDS	206..2521
Translation	MDQPEAPCSSTGPRLAVARELLLAALEELSQEQLKRFRHKLRDVGPDGRSIPWGRLERADAVDLAEQLAQFYGPEPALEVARKTLKRADARDVAAQLQERRLQRLGLGSGTLLSVSEYKKKYREHVLQLHARVKERNARSVKITKRFTKLLIAPESAAPEEAMGPAEEPEPGRARRSDTHTFNRLFRRDEEGRRPLTVVLQGPAGIGKTMAAKKILYDWAAGKLYQGQVDFAFFMPCGELLERPGTRSLADLILDQCPDRGAPVPQMLAQPQRLLFILDGADELPALGGPEAAPCTDPFEAASGARVLGGLLSKALLPTALLLVTTRAAAPGRLQGRLCSPQCAEVRGFSDKDKKKYFYKYFRDERRAERAYRFVKENETLFALCFVPFVCWIVCTVLRQQLELGRDLSRTSKTTTSVYLLFITSVLSSAPVADGPRLQGDLRNLCRLAREGVLGRRAQFAEKELEQLELRGSKVQTLFLSKKELPGVLETEVTYQFIDQSFQEFLAALSYLLEDGGVPRTAAGGVGTLLRGDAQPHSHLVLTTRFLFGLLSAERMRDIERHFGCMVSERVKQEALRWVQGQGQGCPGVAPEVTEGAKGLEDTEEPEEEEEGEEPNYPLELLYCLYETQEDAFVRQALCRFPELALQRVRFCRMDVAVLSYCVRCCPAGQALRLISCRLVAAQEKKKKSLGKRLQASLGGGSSSQGTTKQLPASLLHPLFQAMTDPLCHLSSLTEAAVGNCWVLRSSGGRCSSAGSKVRLSANASRLLRAQ

Target ORF information:

RefSeq Version	XM_017017252.1
Organism	Homo sapiens(human)
Definition	Homo sapiens NLR family, pyrin domain containing 6 (NLRP6), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017017252.1

ORF Insert Sequence:

ATGGACCAGC CAGAGGCCCC CTGCTCCAGC ACGGGGCCGC GCCTCGCGGT GGCCCGCGAG 
CTGCTCCTGG CTGCGCTGGA GGAACTGAGC CAAGAGCAGC TGAAGCGCTT CCGCCACAAG 
CTGCGCGACG TGGGCCCGGA CGGACGCAGC ATCCCGTGGG GGCGGCTGGA GCGCGCGGAC 
GCCGTGGACC TCGCGGAGCA GCTGGCCCAG TTCTACGGCC CGGAGCCTGC CCTGGAGGTG 
GCCCGCAAGA CCCTCAAGAG GGCGGACGCG CGCGACGTGG CGGCGCAGCT CCAGGAGCGG 
CGGCTGCAGC GGCTCGGGCT CGGCTCCGGG ACGCTGCTCT CCGTGTCCGA GTACAAGAAG 
AAGTACCGGG AGCACGTGCT GCAGCTGCAC GCTCGGGTGA AGGAGAGGAA CGCCCGCTCC 
GTGAAGATCA CCAAGCGCTT CACCAAGCTG CTCATCGCGC CCGAGAGCGC CGCCCCGGAG 
GAGGCGATGG GGCCCGCGGA AGAGCCTGAG CCGGGGCGCG CGCGGCGCTC GGACACGCAC 
ACTTTCAACC GCCTCTTCCG CCGCGACGAG GAGGGCCGGC GGCCGCTGAC CGTGGTGCTG 
CAGGGCCCGG CGGGCATCGG CAAGACCATG GCGGCCAAAA AGATCCTGTA CGACTGGGCG 
GCGGGCAAGC TGTACCAGGG CCAGGTGGAC TTCGCCTTCT TCATGCCCTG CGGCGAGCTG 
CTGGAGAGGC CGGGCACGCG CAGCCTGGCT GACCTGATCC TGGACCAGTG CCCCGACCGC 
GGCGCGCCGG TGCCGCAGAT GCTGGCCCAG CCGCAGCGGC TGCTCTTCAT CCTGGACGGC 
GCGGACGAGC TGCCGGCGCT GGGGGGCCCC GAGGCCGCGC CCTGCACAGA CCCCTTCGAG 
GCGGCGAGCG GCGCGCGGGT GCTAGGCGGG CTGCTGAGCA AGGCGCTGCT GCCCACGGCC 
CTCCTGCTGG TGACCACGCG CGCCGCCGCC CCCGGGAGGC TGCAGGGCCG CCTGTGTTCC 
CCGCAGTGCG CCGAGGTGCG CGGCTTCTCC GACAAGGACA AGAAGAAGTA TTTCTACAAG 
TATTTCCGGG ATGAGAGGAG GGCCGAGCGC GCCTACCGCT TCGTGAAGGA GAACGAGACG 
CTGTTCGCGC TGTGCTTCGT GCCCTTCGTG TGCTGGATCG TGTGCACCGT GCTGCGCCAG 
CAGCTGGAGC TCGGTCGGGA CCTGTCGCGC ACGTCCAAGA CCACCACGTC AGTGTACCTG 
CTTTTCATCA CCAGCGTTCT GAGCTCGGCT CCGGTAGCCG ACGGGCCCCG GTTGCAGGGC 
GACCTGCGCA ATCTGTGCCG CCTGGCCCGC GAGGGCGTCC TCGGACGCAG GGCGCAGTTT 
GCCGAGAAGG AACTGGAGCA ACTGGAGCTT CGTGGCTCCA AAGTGCAGAC GCTGTTTCTC 
AGCAAAAAGG AGCTGCCGGG CGTGCTGGAG ACAGAGGTCA CCTACCAGTT CATCGACCAG 
AGCTTCCAGG AGTTCCTCGC GGCACTGTCC TACCTGCTGG AGGACGGCGG GGTGCCCAGG 
ACCGCGGCTG GCGGCGTTGG GACACTCCTG CGTGGGGACG CCCAGCCGCA CAGCCACTTG 
GTGCTCACCA CGCGCTTCCT CTTCGGACTG CTGAGCGCGG AGCGGATGCG CGACATCGAG 
CGCCACTTCG GCTGCATGGT TTCAGAGCGT GTGAAGCAGG AGGCCCTGCG GTGGGTGCAG 
GGACAGGGAC AGGGCTGCCC CGGAGTGGCA CCAGAGGTGA CCGAGGGGGC CAAAGGGCTC 
GAGGACACCG AAGAGCCAGA GGAGGAGGAG GAGGGAGAGG AGCCCAACTA CCCACTGGAG 
TTGCTGTACT GCCTGTACGA GACGCAGGAG GACGCGTTTG TGCGCCAAGC CCTGTGCCGG 
TTCCCGGAGC TGGCGCTGCA GCGAGTGCGC TTCTGCCGCA TGGACGTGGC TGTTCTGAGC 
TACTGCGTGA GGTGCTGCCC TGCTGGACAG GCACTGCGGC TGATCAGCTG CAGATTGGTT 
GCTGCGCAGG AGAAGAAGAA GAAGAGCCTG GGGAAGCGGC TCCAGGCCAG CCTGGGTGGC 
GGCAGCAGTT CTCAAGGCAC CACAAAACAA CTGCCAGCCT CCCTTCTTCA TCCACTCTTT 
CAGGCAATGA CTGACCCACT GTGCCATCTG AGCAGCCTCA CGGAGGCTGC CGTTGGAAAC 
TGCTGGGTTC TCAGAAGCAG TGGAGGAAGG TGTTCAAGCG CAGGCTCCAA GGTCAGGCTG 
TCTGCAAATG CTAGCCGGCT TCTGCGTGCC CAGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

NLRP6 facilitates the interaction between TAB2/3 and TRIM38 in rheumatoid arthritis fibroblast-like synoviocytes.
FEBS letters591(8)1141-1149(2017 04)
Lin Y,Luo Z

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NLRP6 cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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