ADAMTS15 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	ADAMTS15
Entrez Gene ID	170689
Full Name	ADAM metallopeptidase with thrombospondin type 1 motif 15
General protein information	Preferred Names ADAM metallopeptidase with thrombospondin type 1 motif 15 Names A disintegrin and metalloproteinase with thrombospondin motifs 15 ADAM-TS 15 ADAM-TS15 ADAMTS-15 a disintegrin-like and metalloprotease (reprolysin type) with thrombospondin type 1 motif, 15, preproprotein metalloprotease disintegrin 15 with thrombospondin domains
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 11 Map Location: 11q24.3
Summary	This gene encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) protein family. ADAMTS family members share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. The encoded preproprotein is proteolytically processed to generate the mature enzyme, which may play a role in versican processing during skeletal muscle development. This gene may function as a tumor suppressor in colorectal and breast cancers. [provided by RefSeq, May 2016].
Disorder MIM:	607509

mRNA and Protein(s)

mRNA	Protein	Name
NM_139055.2	NP_620686.1	A disintegrin and metalloproteinase with thrombospondin motifs 15 preproprotein
NM_139055.3	NP_620686.1	A disintegrin and metalloproteinase with thrombospondin motifs 15 preproprotein
XM_005271419.4	XP_005271476.1	A disintegrin and metalloproteinase with thrombospondin motifs 15 isoform X1

Pathways from BioSystems

Homologies

	ADAMTS15	XP_001113698.1
Pan troglodytes (chimpanzee)	ADAMTS15	XP_522253.2
Mus musculus (house mouse)	Adamts15	NP_001019310.1
Gallus gallus (chicken)	ADAMTS15	XP_417874.2
Xenopus tropicalis (tropical clawed frog)	adamts15	XP_002938155.2
Homo sapiens (human)	ADAMTS15	NP_620686.1
Canis lupus familiaris (dog)	ADAMTS15	XP_005620352.1
Bos taurus (cattle)	ADAMTS15	NP_001179319.1
Rattus norvegicus (Norway rat)	Adamts15	NP_001100280.1

Gene Ontology
Bibliography

Related articles in PubMed

Versican Proteolysis by ADAMTS Proteases and Its Influence on Sex Steroid Receptor Expression in Uterine Leiomyoma.
Gueye NA, Mead TJ, Koch CD, Biscotti CV, Falcone T, Apte SS
The Journal of clinical endocrinology and metabolism102(5)1631-1641(2017 May)

Human gingiva transcriptome during wound healing.
Wang Y, Tatakis DN
Journal of clinical periodontology44(4)394-402(2017 Apr)

ADAMTS13 and 15 are not regulated by the full length and N-terminal domain forms of TIMP-1, -2, -3 and -4.
Guo C, Tsigkou A, Lee MH
Biomedical reports4(1)73-78(2016 Jan)

Genetic study of intracranial aneurysms.
Yan J, Hitomi T, Takenaka K, Kato M, Kobayashi H, Okuda H, Harada KH, Koizumi A
Stroke46(3)620-6(2015 Mar)

Metalloproteinase-dependent and -independent processes contribute to inhibition of breast cancer cell migration, angiogenesis and liver metastasis by a disintegrin and metalloproteinase with thrombospondin motifs-15.
Kelwick R, Wagstaff L, Decock J, Roghi C, Cooley LS, Robinson SD, Arnold H, Gavrilovi? J, Jaworski DM, Yamamoto K, Nagase H, Seubert B, Kr?ger A, Edwards DR
International journal of cancer136(4)E14-26(2015 Feb)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

ADAMTS4 and ADAMTS15 were upregulated in symptomatic uterine leiomyomas.
Title: Versican Proteolysis by ADAMTS Proteases and Its Influence on Sex Steroid Receptor Expression in Uterine Leiomyoma.

ADAMTS15 expression is significantly upregulated in human masticatory mucosa during wound healing
Title: Human gingiva transcriptome during wound healing.

ADAMTS15 is a candidate gene for intracranial aneurysms
Title: Genetic study of intracranial aneurysms.

ADAMTS-15 has multiple actions on tumor pathophysiology including modulation of cell-extracellular matrix interactions, which likely involve syndecan-4.
Title: Metalloproteinase-dependent and -independent processes contribute to inhibition of breast cancer cell migration, angiogenesis and liver metastasis by a disintegrin and metalloproteinase with thrombospondin motifs-15.

Versican processing by ADAMTS5 and ADAMTS15 contribute to muscle fiber formation.
Title: Versican processing by a disintegrin-like and metalloproteinase domain with thrombospondin-1 repeats proteinases-5 and -15 facilitates myoblast fusion.

The following ADAMTS15 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the ADAMTS15 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu12405	NM_139055.3 Latest version!	Homo sapiens ADAM metallopeptidase with thrombospondin type 1 motif 15 (ADAMTS15), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$469.50-$657.30 $939.00
OHu45664	XM_005271419.4 Latest version!	Homo sapiens ADAM metallopeptidase with thrombospondin type 1 motif 15 (ADAMTS15), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$307.30 $439.00
View Old Accession Versions >>
OHu12405	NM_139055.2	Homo sapiens ADAM metallopeptidase with thrombospondin type 1 motif, 15 (ADAMTS15), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$469.50-$657.30 $939.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

ADAMTS15 ( NM_139055.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_620686.1 Homo sapiens ADAM metallopeptidase with thrombospondin type 1 motif, 15 (ADAMTS15), mRNA.

Price & Availability↑

CloneID	OHu12405
Clone ID Related Accession (Same CDS sequence)	NM_139055.2 , NM_139055.3
Accession Version	NM_139055.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2853bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2015-03-14
Organism	Homo sapiens(Human)
Product	A disintegrin and metalloproteinase with thrombospondin motifs 15 preproprotein
Comment

ATGCTTCTGC TGGGCATCCT AACCCTGGCT TTCGCCGGGC GAACCGCTGG AGGCTCTGAG 
CCAGAGCGGG AGGTAGTCGT TCCCATCCGA CTGGACCCGG ACATTAACGG CCGCCGCTAC 
TACTGGCGGG GTCCCGAGGA CTCCGGGGAT CAGGGACTCA TTTTTCAGAT CACAGCATTT 
CAGGAGGACT TTTACCTACA CCTGACGCCG GATGCTCAGT TCTTGGCTCC CGCCTTCTCC 
ACTGAGCATC TGGGCGTCCC CCTCCAGGGG CTCACCGGGG GCTCTTCAGA CCTGCGACGC 
TGCTTCTATT CTGGGGACGT GAACGCCGAG CCGGACTCGT TCGCTGCTGT GAGCCTGTGC 
GGGGGGCTCC GCGGAGCCTT TGGCTACCGA GGCGCCGAGT ATGTCATTAG CCCGCTGCCC 
AATGCTAGCG CGCCGGCGGC GCAGCGCAAC AGCCAGGGCG CACACCTTCT CCAGCGCCGG 
GGTGTTCCGG GCGGGCCTTC CGGAGACCCC ACCTCTCGCT GCGGGGTGGC CTCGGGCTGG 
AACCCCGCCA TCCTACGGGC CCTGGACCCT TACAAGCCGC GGCGGGCGGG CTTCGGGGAG 
AGTCGTAGCC GGCGCAGGTC TGGGCGCGCC AAGCGTTTCG TGTCTATCCC GCGGTACGTG 
GAGACGCTGG TGGTCGCGGA CGAGTCAATG GTCAAGTTCC ACGGCGCGGA CCTGGAACAT 
TATCTGCTGA CGCTGCTGGC AACGGCGGCG CGACTCTACC GCCATCCCAG CATCCTCAAC 
CCCATCAACA TCGTTGTGGT CAAGGTGCTG CTTCTTAGAG ATCGTGACTC CGGGCCCAAG 
GTCACCGGCA ATGCGGCCCT GACGCTGCGC AACTTCTGTG CCTGGCAGAA GAAGCTGAAC 
AAAGTGAGTG ACAAGCACCC CGAGTACTGG GACACTGCCA TCCTCTTCAC CAGGCAGGAC 
CTGTGTGGAG CCACCACCTG TGACACCCTG GGCATGGCTG ATGTGGGTAC CATGTGTGAC 
CCCAAGAGAA GCTGCTCTGT CATTGAGGAC GATGGGCTTC CATCAGCCTT CACCACTGCC 
CACGAGCTGG GCCACGTGTT CAACATGCCC CATGACAATG TGAAAGTCTG TGAGGAGGTG 
TTTGGGAAGC TCCGAGCCAA CCACATGATG TCCCCGACCC TCATCCAGAT CGACCGTGCC 
AACCCCTGGT CAGCCTGCAG TGCTGCCATC ATCACCGACT TCCTGGACAG CGGGCACGGT 
GACTGCCTCC TGGACCAACC CAGCAAGCCC ATCTCCCTGC CCGAGGATCT GCCGGGCGCC 
AGCTACACCC TGAGCCAGCA GTGCGAGCTG GCTTTTGGCG TGGGCTCCAA GCCCTGTCCT 
TACATGCAGT ACTGCACCAA GCTGTGGTGC ACCGGGAAGG CCAAGGGACA GATGGTGTGC 
CAGACCCGCC ACTTCCCCTG GGCCGATGGC ACCAGCTGTG GCGAGGGCAA GCTCTGCCTC 
AAAGGGGCCT GCGTGGAGAG ACACAACCTC AACAAGCACA GGGTGGATGG TTCCTGGGCC 
AAATGGGATC CCTATGGCCC CTGCTCGCGC ACATGTGGTG GGGGCGTGCA GCTGGCCAGG 
AGGCAGTGCA CCAACCCCAC CCCTGCCAAC GGGGGCAAGT ACTGCGAGGG AGTGAGGGTG 
AAATACCGAT CCTGCAATCT GGAGCCCTGC CCCAGCTCAG CCTCCGGAAA GAGCTTCCGG 
GAGGAGCAGT GTGAGGCTTT CAACGGCTAC AACCACAGCA CCAACCGGCT CACTCTCGCC 
GTGGCATGGG TGCCCAAGTA CTCCGGCGTG TCTCCCCGGG ACAAGTGCAA GCTCATCTGC 
CGAGCCAATG GCACTGGCTA CTTCTATGTG CTGGCACCCA AGGTGGTGGA CGGCACGCTG 
TGCTCTCCTG ACTCCACCTC CGTCTGTGTC CAAGGCAAGT GCATCAAGGC TGGCTGTGAT 
GGGAACCTGG GCTCCAAGAA GAGATTCGAC AAGTGTGGGG TGTGTGGGGG AGACAATAAG 
AGCTGCAAGA AGGTGACTGG ACTCTTCACC AAGCCCATGC ATGGCTACAA TTTCGTGGTG 
GCCATCCCCG CAGGCGCCTC AAGCATCGAC ATCCGCCAGC GCGGTTACAA AGGGCTGATC 
GGGGATGACA ACTACCTGGC TCTGAAGAAC AGCCAAGGCA AGTACCTGCT CAACGGGCAT 
TTCGTGGTGT CGGCGGTGGA GCGGGACCTG GTGGTGAAGG GCAGTCTGCT GCGGTACAGC 
GGCACGGGCA CAGCGGTGGA GAGCCTGCAG GCTTCCCGGC CCATCCTGGA GCCGCTGACC 
GTGGAGGTCC TCTCCGTGGG GAAGATGACA CCGCCCCGGG TCCGCTACTC CTTCTATCTG 
CCCAAAGAGC CTCGGGAGGA CAAGTCCTCT CATCCCAAGG ACCCCCGGGG ACCCTCTGTC 
TTGCACAACA GCGTCCTCAG CCTCTCCAAC CAGGTGGAGC AGCCGGACGA CAGGCCCCCT 
GCACGCTGGG TGGCTGGCAG CTGGGGGCCG TGCTCCGCGA GCTGCGGCAG TGGCCTGCAG 
AAGCGGGCGG TGGACTGCCG GGGCTCCGCC GGGCAGCGCA CGGTCCCTGC CTGTGATGCA 
GCCCATCGGC CCGTGGAGAC ACAAGCCTGC GGGGAGCCCT GCCCCACCTG GGAGCTCAGC 
GCCTGGTCAC CCTGCTCCAA GAGCTGCGGC CGGGGATTTC AGAGGCGCTC ACTCAAGTGT 
GTGGGCCACG GAGGCCGGCT GCTGGCCCGG GACCAGTGCA ACTTGCACCG CAAGCCCCAG 
GAGCTGGACT TCTGCGTCCT GAGGCCGTGC TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq

NP_620686.1

Translation

MLLLGILTLAFAGRTAGGSEPEREVVVPIRLDPDINGRRYYWRGPEDSGDQGLIFQITAFQEDFYLHLTPDAQFLAPAFSTEHLGVPLQGLTGGSSDLRRCFYSGDVNAEPDSFAAVSLCGGLRGAFGYRGAEYVISPLPNASAPAAQRNSQGAHLLQRRGVPGGPSGDPTSRCGVASGWNPAILRALDPYKPRRAGFGESRSRRRSGRAKRFVSIPRYVETLVVADESMVKFHGADLEHYLLTLLATAARLYRHPSILNPINIVVVKVLLLRDRDSGPKVTGNAALTLRNFCAWQKKLNKVSDKHPEYWDTAILFTRQDLCGATTCDTLGMADVGTMCDPKRSCSVIEDDGLPSAFTTAHELGHVFNMPHDNVKVCEEVFGKLRANHMMSPTLIQIDRANPWSACSAAIITDFLDSGHGDCLLDQPSKPISLPEDLPGASYTLSQQCELAFGVGSKPCPYMQYCTKLWCTGKAKGQMVCQTRHFPWADGTSCGEGKLCLKGACVERHNLNKHRVDGSWAKWDPYGPCSRTCGGGVQLARRQCTNPTPANGGKYCEGVRVKYRSCNLEPCPSSASGKSFREEQCEAFNGYNHSTNRLTLAVAWVPKYSGVSPRDKCKLICRANGTGYFYVLAPKVVDGTLCSPDSTSVCVQGKCIKAGCDGNLGSKKRFDKCGVCGGDNKSCKKVTGLFTKPMHGYNFVVAIPAGASSIDIRQRGYKGLIGDDNYLALKNSQGKYLLNGHFVVSAVERDLVVKGSLLRYSGTGTAVESLQASRPILEPLTVEVLSVGKMTPPRVRYSFYLPKEPREDKSSHPKDPRGPSVLHNSVLSLSNQVEQPDDRPPARWVAGSWGPCSASCGSGLQKRAVDCRGSAGQRTVPACDAAHRPVETQACGEPCPTWELSAWSPCSKSCGRGFQRRSLKCVGHGGRLLARDQCNLHRKPQELDFCVLRPC

Target ORF information:

RefSeq Version	NM_139055.2
Organism	Homo sapiens(Human)
Definition	Homo sapiens ADAM metallopeptidase with thrombospondin type 1 motif, 15 (ADAMTS15), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_139055.2

ORF Insert Sequence:

ATGCTTCTGC TGGGCATCCT AACCCTGGCT TTCGCCGGGC GAACCGCTGG AGGCTCTGAG 
CCAGAGCGGG AGGTAGTCGT TCCCATCCGA CTGGACCCGG ACATTAACGG CCGCCGCTAC 
TACTGGCGGG GTCCCGAGGA CTCCGGGGAT CAGGGACTCA TTTTTCAGAT CACAGCATTT 
CAGGAGGACT TTTACCTACA CCTGACGCCG GATGCTCAGT TCTTGGCTCC CGCCTTCTCC 
ACTGAGCATC TGGGCGTCCC CCTCCAGGGG CTCACCGGGG GCTCTTCAGA CCTGCGACGC 
TGCTTCTATT CTGGGGACGT GAACGCCGAG CCGGACTCGT TCGCTGCTGT GAGCCTGTGC 
GGGGGGCTCC GCGGAGCCTT TGGCTACCGA GGCGCCGAGT ATGTCATTAG CCCGCTGCCC 
AATGCTAGCG CGCCGGCGGC GCAGCGCAAC AGCCAGGGCG CACACCTTCT CCAGCGCCGG 
GGTGTTCCGG GCGGGCCTTC CGGAGACCCC ACCTCTCGCT GCGGGGTGGC CTCGGGCTGG 
AACCCCGCCA TCCTACGGGC CCTGGACCCT TACAAGCCGC GGCGGGCGGG CTTCGGGGAG 
AGTCGTAGCC GGCGCAGGTC TGGGCGCGCC AAGCGTTTCG TGTCTATCCC GCGGTACGTG 
GAGACGCTGG TGGTCGCGGA CGAGTCAATG GTCAAGTTCC ACGGCGCGGA CCTGGAACAT 
TATCTGCTGA CGCTGCTGGC AACGGCGGCG CGACTCTACC GCCATCCCAG CATCCTCAAC 
CCCATCAACA TCGTTGTGGT CAAGGTGCTG CTTCTTAGAG ATCGTGACTC CGGGCCCAAG 
GTCACCGGCA ATGCGGCCCT GACGCTGCGC AACTTCTGTG CCTGGCAGAA GAAGCTGAAC 
AAAGTGAGTG ACAAGCACCC CGAGTACTGG GACACTGCCA TCCTCTTCAC CAGGCAGGAC 
CTGTGTGGAG CCACCACCTG TGACACCCTG GGCATGGCTG ATGTGGGTAC CATGTGTGAC 
CCCAAGAGAA GCTGCTCTGT CATTGAGGAC GATGGGCTTC CATCAGCCTT CACCACTGCC 
CACGAGCTGG GCCACGTGTT CAACATGCCC CATGACAATG TGAAAGTCTG TGAGGAGGTG 
TTTGGGAAGC TCCGAGCCAA CCACATGATG TCCCCGACCC TCATCCAGAT CGACCGTGCC 
AACCCCTGGT CAGCCTGCAG TGCTGCCATC ATCACCGACT TCCTGGACAG CGGGCACGGT 
GACTGCCTCC TGGACCAACC CAGCAAGCCC ATCTCCCTGC CCGAGGATCT GCCGGGCGCC 
AGCTACACCC TGAGCCAGCA GTGCGAGCTG GCTTTTGGCG TGGGCTCCAA GCCCTGTCCT 
TACATGCAGT ACTGCACCAA GCTGTGGTGC ACCGGGAAGG CCAAGGGACA GATGGTGTGC 
CAGACCCGCC ACTTCCCCTG GGCCGATGGC ACCAGCTGTG GCGAGGGCAA GCTCTGCCTC 
AAAGGGGCCT GCGTGGAGAG ACACAACCTC AACAAGCACA GGGTGGATGG TTCCTGGGCC 
AAATGGGATC CCTATGGCCC CTGCTCGCGC ACATGTGGTG GGGGCGTGCA GCTGGCCAGG 
AGGCAGTGCA CCAACCCCAC CCCTGCCAAC GGGGGCAAGT ACTGCGAGGG AGTGAGGGTG 
AAATACCGAT CCTGCAATCT GGAGCCCTGC CCCAGCTCAG CCTCCGGAAA GAGCTTCCGG 
GAGGAGCAGT GTGAGGCTTT CAACGGCTAC AACCACAGCA CCAACCGGCT CACTCTCGCC 
GTGGCATGGG TGCCCAAGTA CTCCGGCGTG TCTCCCCGGG ACAAGTGCAA GCTCATCTGC 
CGAGCCAATG GCACTGGCTA CTTCTATGTG CTGGCACCCA AGGTGGTGGA CGGCACGCTG 
TGCTCTCCTG ACTCCACCTC CGTCTGTGTC CAAGGCAAGT GCATCAAGGC TGGCTGTGAT 
GGGAACCTGG GCTCCAAGAA GAGATTCGAC AAGTGTGGGG TGTGTGGGGG AGACAATAAG 
AGCTGCAAGA AGGTGACTGG ACTCTTCACC AAGCCCATGC ATGGCTACAA TTTCGTGGTG 
GCCATCCCCG CAGGCGCCTC AAGCATCGAC ATCCGCCAGC GCGGTTACAA AGGGCTGATC 
GGGGATGACA ACTACCTGGC TCTGAAGAAC AGCCAAGGCA AGTACCTGCT CAACGGGCAT 
TTCGTGGTGT CGGCGGTGGA GCGGGACCTG GTGGTGAAGG GCAGTCTGCT GCGGTACAGC 
GGCACGGGCA CAGCGGTGGA GAGCCTGCAG GCTTCCCGGC CCATCCTGGA GCCGCTGACC 
GTGGAGGTCC TCTCCGTGGG GAAGATGACA CCGCCCCGGG TCCGCTACTC CTTCTATCTG 
CCCAAAGAGC CTCGGGAGGA CAAGTCCTCT CATCCCAAGG ACCCCCGGGG ACCCTCTGTC 
TTGCACAACA GCGTCCTCAG CCTCTCCAAC CAGGTGGAGC AGCCGGACGA CAGGCCCCCT 
GCACGCTGGG TGGCTGGCAG CTGGGGGCCG TGCTCCGCGA GCTGCGGCAG TGGCCTGCAG 
AAGCGGGCGG TGGACTGCCG GGGCTCCGCC GGGCAGCGCA CGGTCCCTGC CTGTGATGCA 
GCCCATCGGC CCGTGGAGAC ACAAGCCTGC GGGGAGCCCT GCCCCACCTG GGAGCTCAGC 
GCCTGGTCAC CCTGCTCCAA GAGCTGCGGC CGGGGATTTC AGAGGCGCTC ACTCAAGTGT 
GTGGGCCACG GAGGCCGGCT GCTGGCCCGG GACCAGTGCA ACTTGCACCG CAAGCCCCAG 
GAGCTGGACT TCTGCGTCCT GAGGCCGTGC TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

ADAMTS15 ( NM_139055.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_620686.1 Homo sapiens ADAM metallopeptidase with thrombospondin type 1 motif 15 (ADAMTS15), mRNA.

Price & Availability↑

CloneID	OHu12405
Clone ID Related Accession (Same CDS sequence)	NM_139055.2 , NM_139055.3
Accession Version	NM_139055.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2853bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-28
Organism	Homo sapiens(human)
Product	A disintegrin and metalloproteinase with thrombospondin motifs 15 preproprotein
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BC109114.1, AP003459.2, AK130067.1 and W70305.1. On May 13, 2016 this sequence version replaced NM_139055.2. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC109114.1, AJ315733.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968189, SAMEA1968540 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## RefSeq Select criteria :: based on conservation, expression, longest protein ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGCTTCTGC TGGGCATCCT AACCCTGGCT TTCGCCGGGC GAACCGCTGG AGGCTCTGAG 
CCAGAGCGGG AGGTAGTCGT TCCCATCCGA CTGGACCCGG ACATTAACGG CCGCCGCTAC 
TACTGGCGGG GTCCCGAGGA CTCCGGGGAT CAGGGACTCA TTTTTCAGAT CACAGCATTT 
CAGGAGGACT TTTACCTACA CCTGACGCCG GATGCTCAGT TCTTGGCTCC CGCCTTCTCC 
ACTGAGCATC TGGGCGTCCC CCTCCAGGGG CTCACCGGGG GCTCTTCAGA CCTGCGACGC 
TGCTTCTATT CTGGGGACGT GAACGCCGAG CCGGACTCGT TCGCTGCTGT GAGCCTGTGC 
GGGGGGCTCC GCGGAGCCTT TGGCTACCGA GGCGCCGAGT ATGTCATTAG CCCGCTGCCC 
AATGCTAGCG CGCCGGCGGC GCAGCGCAAC AGCCAGGGCG CACACCTTCT CCAGCGCCGG 
GGTGTTCCGG GCGGGCCTTC CGGAGACCCC ACCTCTCGCT GCGGGGTGGC CTCGGGCTGG 
AACCCCGCCA TCCTACGGGC CCTGGACCCT TACAAGCCGC GGCGGGCGGG CTTCGGGGAG 
AGTCGTAGCC GGCGCAGGTC TGGGCGCGCC AAGCGTTTCG TGTCTATCCC GCGGTACGTG 
GAGACGCTGG TGGTCGCGGA CGAGTCAATG GTCAAGTTCC ACGGCGCGGA CCTGGAACAT 
TATCTGCTGA CGCTGCTGGC AACGGCGGCG CGACTCTACC GCCATCCCAG CATCCTCAAC 
CCCATCAACA TCGTTGTGGT CAAGGTGCTG CTTCTTAGAG ATCGTGACTC CGGGCCCAAG 
GTCACCGGCA ATGCGGCCCT GACGCTGCGC AACTTCTGTG CCTGGCAGAA GAAGCTGAAC 
AAAGTGAGTG ACAAGCACCC CGAGTACTGG GACACTGCCA TCCTCTTCAC CAGGCAGGAC 
CTGTGTGGAG CCACCACCTG TGACACCCTG GGCATGGCTG ATGTGGGTAC CATGTGTGAC 
CCCAAGAGAA GCTGCTCTGT CATTGAGGAC GATGGGCTTC CATCAGCCTT CACCACTGCC 
CACGAGCTGG GCCACGTGTT CAACATGCCC CATGACAATG TGAAAGTCTG TGAGGAGGTG 
TTTGGGAAGC TCCGAGCCAA CCACATGATG TCCCCGACCC TCATCCAGAT CGACCGTGCC 
AACCCCTGGT CAGCCTGCAG TGCTGCCATC ATCACCGACT TCCTGGACAG CGGGCACGGT 
GACTGCCTCC TGGACCAACC CAGCAAGCCC ATCTCCCTGC CCGAGGATCT GCCGGGCGCC 
AGCTACACCC TGAGCCAGCA GTGCGAGCTG GCTTTTGGCG TGGGCTCCAA GCCCTGTCCT 
TACATGCAGT ACTGCACCAA GCTGTGGTGC ACCGGGAAGG CCAAGGGACA GATGGTGTGC 
CAGACCCGCC ACTTCCCCTG GGCCGATGGC ACCAGCTGTG GCGAGGGCAA GCTCTGCCTC 
AAAGGGGCCT GCGTGGAGAG ACACAACCTC AACAAGCACA GGGTGGATGG TTCCTGGGCC 
AAATGGGATC CCTATGGCCC CTGCTCGCGC ACATGTGGTG GGGGCGTGCA GCTGGCCAGG 
AGGCAGTGCA CCAACCCCAC CCCTGCCAAC GGGGGCAAGT ACTGCGAGGG AGTGAGGGTG 
AAATACCGAT CCTGCAATCT GGAGCCCTGC CCCAGCTCAG CCTCCGGAAA GAGCTTCCGG 
GAGGAGCAGT GTGAGGCTTT CAACGGCTAC AACCACAGCA CCAACCGGCT CACTCTCGCC 
GTGGCATGGG TGCCCAAGTA CTCCGGCGTG TCTCCCCGGG ACAAGTGCAA GCTCATCTGC 
CGAGCCAATG GCACTGGCTA CTTCTATGTG CTGGCACCCA AGGTGGTGGA CGGCACGCTG 
TGCTCTCCTG ACTCCACCTC CGTCTGTGTC CAAGGCAAGT GCATCAAGGC TGGCTGTGAT 
GGGAACCTGG GCTCCAAGAA GAGATTCGAC AAGTGTGGGG TGTGTGGGGG AGACAATAAG 
AGCTGCAAGA AGGTGACTGG ACTCTTCACC AAGCCCATGC ATGGCTACAA TTTCGTGGTG 
GCCATCCCCG CAGGCGCCTC AAGCATCGAC ATCCGCCAGC GCGGTTACAA AGGGCTGATC 
GGGGATGACA ACTACCTGGC TCTGAAGAAC AGCCAAGGCA AGTACCTGCT CAACGGGCAT 
TTCGTGGTGT CGGCGGTGGA GCGGGACCTG GTGGTGAAGG GCAGTCTGCT GCGGTACAGC 
GGCACGGGCA CAGCGGTGGA GAGCCTGCAG GCTTCCCGGC CCATCCTGGA GCCGCTGACC 
GTGGAGGTCC TCTCCGTGGG GAAGATGACA CCGCCCCGGG TCCGCTACTC CTTCTATCTG 
CCCAAAGAGC CTCGGGAGGA CAAGTCCTCT CATCCCAAGG ACCCCCGGGG ACCCTCTGTC 
TTGCACAACA GCGTCCTCAG CCTCTCCAAC CAGGTGGAGC AGCCGGACGA CAGGCCCCCT 
GCACGCTGGG TGGCTGGCAG CTGGGGGCCG TGCTCCGCGA GCTGCGGCAG TGGCCTGCAG 
AAGCGGGCGG TGGACTGCCG GGGCTCCGCC GGGCAGCGCA CGGTCCCTGC CTGTGATGCA 
GCCCATCGGC CCGTGGAGAC ACAAGCCTGC GGGGAGCCCT GCCCCACCTG GGAGCTCAGC 
GCCTGGTCAC CCTGCTCCAA GAGCTGCGGC CGGGGATTTC AGAGGCGCTC ACTCAAGTGT 
GTGGGCCACG GAGGCCGGCT GCTGGCCCGG GACCAGTGCA ACTTGCACCG CAAGCCCCAG 
GAGCTGGACT TCTGCGTCCT GAGGCCGTGC TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_620686.1
CDS	1..2853
Translation	MLLLGILTLAFAGRTAGGSEPEREVVVPIRLDPDINGRRYYWRGPEDSGDQGLIFQITAFQEDFYLHLTPDAQFLAPAFSTEHLGVPLQGLTGGSSDLRRCFYSGDVNAEPDSFAAVSLCGGLRGAFGYRGAEYVISPLPNASAPAAQRNSQGAHLLQRRGVPGGPSGDPTSRCGVASGWNPAILRALDPYKPRRAGFGESRSRRRSGRAKRFVSIPRYVETLVVADESMVKFHGADLEHYLLTLLATAARLYRHPSILNPINIVVVKVLLLRDRDSGPKVTGNAALTLRNFCAWQKKLNKVSDKHPEYWDTAILFTRQDLCGATTCDTLGMADVGTMCDPKRSCSVIEDDGLPSAFTTAHELGHVFNMPHDNVKVCEEVFGKLRANHMMSPTLIQIDRANPWSACSAAIITDFLDSGHGDCLLDQPSKPISLPEDLPGASYTLSQQCELAFGVGSKPCPYMQYCTKLWCTGKAKGQMVCQTRHFPWADGTSCGEGKLCLKGACVERHNLNKHRVDGSWAKWDPYGPCSRTCGGGVQLARRQCTNPTPANGGKYCEGVRVKYRSCNLEPCPSSASGKSFREEQCEAFNGYNHSTNRLTLAVAWVPKYSGVSPRDKCKLICRANGTGYFYVLAPKVVDGTLCSPDSTSVCVQGKCIKAGCDGNLGSKKRFDKCGVCGGDNKSCKKVTGLFTKPMHGYNFVVAIPAGASSIDIRQRGYKGLIGDDNYLALKNSQGKYLLNGHFVVSAVERDLVVKGSLLRYSGTGTAVESLQASRPILEPLTVEVLSVGKMTPPRVRYSFYLPKEPREDKSSHPKDPRGPSVLHNSVLSLSNQVEQPDDRPPARWVAGSWGPCSASCGSGLQKRAVDCRGSAGQRTVPACDAAHRPVETQACGEPCPTWELSAWSPCSKSCGRGFQRRSLKCVGHGGRLLARDQCNLHRKPQELDFCVLRPC

Target ORF information:

RefSeq Version	NM_139055.3
Organism	Homo sapiens(human)
Definition	Homo sapiens ADAM metallopeptidase with thrombospondin type 1 motif 15 (ADAMTS15), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_139055.3

ORF Insert Sequence:

ATGCTTCTGC TGGGCATCCT AACCCTGGCT TTCGCCGGGC GAACCGCTGG AGGCTCTGAG 
CCAGAGCGGG AGGTAGTCGT TCCCATCCGA CTGGACCCGG ACATTAACGG CCGCCGCTAC 
TACTGGCGGG GTCCCGAGGA CTCCGGGGAT CAGGGACTCA TTTTTCAGAT CACAGCATTT 
CAGGAGGACT TTTACCTACA CCTGACGCCG GATGCTCAGT TCTTGGCTCC CGCCTTCTCC 
ACTGAGCATC TGGGCGTCCC CCTCCAGGGG CTCACCGGGG GCTCTTCAGA CCTGCGACGC 
TGCTTCTATT CTGGGGACGT GAACGCCGAG CCGGACTCGT TCGCTGCTGT GAGCCTGTGC 
GGGGGGCTCC GCGGAGCCTT TGGCTACCGA GGCGCCGAGT ATGTCATTAG CCCGCTGCCC 
AATGCTAGCG CGCCGGCGGC GCAGCGCAAC AGCCAGGGCG CACACCTTCT CCAGCGCCGG 
GGTGTTCCGG GCGGGCCTTC CGGAGACCCC ACCTCTCGCT GCGGGGTGGC CTCGGGCTGG 
AACCCCGCCA TCCTACGGGC CCTGGACCCT TACAAGCCGC GGCGGGCGGG CTTCGGGGAG 
AGTCGTAGCC GGCGCAGGTC TGGGCGCGCC AAGCGTTTCG TGTCTATCCC GCGGTACGTG 
GAGACGCTGG TGGTCGCGGA CGAGTCAATG GTCAAGTTCC ACGGCGCGGA CCTGGAACAT 
TATCTGCTGA CGCTGCTGGC AACGGCGGCG CGACTCTACC GCCATCCCAG CATCCTCAAC 
CCCATCAACA TCGTTGTGGT CAAGGTGCTG CTTCTTAGAG ATCGTGACTC CGGGCCCAAG 
GTCACCGGCA ATGCGGCCCT GACGCTGCGC AACTTCTGTG CCTGGCAGAA GAAGCTGAAC 
AAAGTGAGTG ACAAGCACCC CGAGTACTGG GACACTGCCA TCCTCTTCAC CAGGCAGGAC 
CTGTGTGGAG CCACCACCTG TGACACCCTG GGCATGGCTG ATGTGGGTAC CATGTGTGAC 
CCCAAGAGAA GCTGCTCTGT CATTGAGGAC GATGGGCTTC CATCAGCCTT CACCACTGCC 
CACGAGCTGG GCCACGTGTT CAACATGCCC CATGACAATG TGAAAGTCTG TGAGGAGGTG 
TTTGGGAAGC TCCGAGCCAA CCACATGATG TCCCCGACCC TCATCCAGAT CGACCGTGCC 
AACCCCTGGT CAGCCTGCAG TGCTGCCATC ATCACCGACT TCCTGGACAG CGGGCACGGT 
GACTGCCTCC TGGACCAACC CAGCAAGCCC ATCTCCCTGC CCGAGGATCT GCCGGGCGCC 
AGCTACACCC TGAGCCAGCA GTGCGAGCTG GCTTTTGGCG TGGGCTCCAA GCCCTGTCCT 
TACATGCAGT ACTGCACCAA GCTGTGGTGC ACCGGGAAGG CCAAGGGACA GATGGTGTGC 
CAGACCCGCC ACTTCCCCTG GGCCGATGGC ACCAGCTGTG GCGAGGGCAA GCTCTGCCTC 
AAAGGGGCCT GCGTGGAGAG ACACAACCTC AACAAGCACA GGGTGGATGG TTCCTGGGCC 
AAATGGGATC CCTATGGCCC CTGCTCGCGC ACATGTGGTG GGGGCGTGCA GCTGGCCAGG 
AGGCAGTGCA CCAACCCCAC CCCTGCCAAC GGGGGCAAGT ACTGCGAGGG AGTGAGGGTG 
AAATACCGAT CCTGCAATCT GGAGCCCTGC CCCAGCTCAG CCTCCGGAAA GAGCTTCCGG 
GAGGAGCAGT GTGAGGCTTT CAACGGCTAC AACCACAGCA CCAACCGGCT CACTCTCGCC 
GTGGCATGGG TGCCCAAGTA CTCCGGCGTG TCTCCCCGGG ACAAGTGCAA GCTCATCTGC 
CGAGCCAATG GCACTGGCTA CTTCTATGTG CTGGCACCCA AGGTGGTGGA CGGCACGCTG 
TGCTCTCCTG ACTCCACCTC CGTCTGTGTC CAAGGCAAGT GCATCAAGGC TGGCTGTGAT 
GGGAACCTGG GCTCCAAGAA GAGATTCGAC AAGTGTGGGG TGTGTGGGGG AGACAATAAG 
AGCTGCAAGA AGGTGACTGG ACTCTTCACC AAGCCCATGC ATGGCTACAA TTTCGTGGTG 
GCCATCCCCG CAGGCGCCTC AAGCATCGAC ATCCGCCAGC GCGGTTACAA AGGGCTGATC 
GGGGATGACA ACTACCTGGC TCTGAAGAAC AGCCAAGGCA AGTACCTGCT CAACGGGCAT 
TTCGTGGTGT CGGCGGTGGA GCGGGACCTG GTGGTGAAGG GCAGTCTGCT GCGGTACAGC 
GGCACGGGCA CAGCGGTGGA GAGCCTGCAG GCTTCCCGGC CCATCCTGGA GCCGCTGACC 
GTGGAGGTCC TCTCCGTGGG GAAGATGACA CCGCCCCGGG TCCGCTACTC CTTCTATCTG 
CCCAAAGAGC CTCGGGAGGA CAAGTCCTCT CATCCCAAGG ACCCCCGGGG ACCCTCTGTC 
TTGCACAACA GCGTCCTCAG CCTCTCCAAC CAGGTGGAGC AGCCGGACGA CAGGCCCCCT 
GCACGCTGGG TGGCTGGCAG CTGGGGGCCG TGCTCCGCGA GCTGCGGCAG TGGCCTGCAG 
AAGCGGGCGG TGGACTGCCG GGGCTCCGCC GGGCAGCGCA CGGTCCCTGC CTGTGATGCA 
GCCCATCGGC CCGTGGAGAC ACAAGCCTGC GGGGAGCCCT GCCCCACCTG GGAGCTCAGC 
GCCTGGTCAC CCTGCTCCAA GAGCTGCGGC CGGGGATTTC AGAGGCGCTC ACTCAAGTGT 
GTGGGCCACG GAGGCCGGCT GCTGGCCCGG GACCAGTGCA ACTTGCACCG CAAGCCCCAG 
GAGCTGGACT TCTGCGTCCT GAGGCCGTGC TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

ADAMTS15 ( XM_005271419.4 ) cDNA ORF clone, Homo sapiens(human) -> XP_005271476.1 Homo sapiens ADAM metallopeptidase with thrombospondin type 1 motif 15 (ADAMTS15), transcript variant X2, mRNA.

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CloneID	OHu45664
Clone ID Related Accession (Same CDS sequence)	XM_005271419.4
Accession Version	XM_005271419.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1860bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	A disintegrin and metalloproteinase with thrombospondin motifs 15 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000011.10) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 6, 2016 this sequence version replaced XM_005271419.3. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGCTGATG TGGGTACCAT GTGTGACCCC AAGAGAAGCT GCTCTGTCAT TGAGGACGAT 
GGGCTTCCAT CAGCCTTCAC CACTGCCCAC GAGCTGGGCC ACGTGTTCAA CATGCCCCAT 
GACAATGTGA AAGTCTGTGA GGAGGTGTTT GGGAAGCTCC GAGCCAACCA CATGATGTCC 
CCGACCCTCA TCCAGATCGA CCGTGCCAAC CCCTGGTCAG CCTGCAGTGC TGCCATCATC 
ACCGACTTCC TGGACAGCGG GCACGGTGAC TGCCTCCTGG ACCAACCCAG CAAGCCCATC 
TCCCTGCCCG AGGATCTGCC GGGCGCCAGC TACACCCTGA GCCAGCAGTG CGAGCTGGCT 
TTTGGCGTGG GCTCCAAGCC CTGTCCTTAC ATGCAGTACT GCACCAAGCT GTGGTGCACC 
GGGAAGGCCA AGGGACAGAT GGTGTGCCAG ACCCGCCACT TCCCCTGGGC CGATGGCACC 
AGCTGTGGCG AGGGCAAGCT CTGCCTCAAA GGGGCCTGCG TGGAGAGACA CAACCTCAAC 
AAGCACAGGG TGGATGGTTC CTGGGCCAAA TGGGATCCCT ATGGCCCCTG CTCGCGCACA 
TGTGGTGGGG GCGTGCAGCT GGCCAGGAGG CAGTGCACCA ACCCCACCCC TGCCAACGGG 
GGCAAGTACT GCGAGGGAGT GAGGGTGAAA TACCGATCCT GCAATCTGGA GCCCTGCCCC 
AGCTCAGCCT CCGGAAAGAG CTTCCGGGAG GAGCAGTGTG AGGCTTTCAA CGGCTACAAC 
CACAGCACCA ACCGGCTCAC TCTCGCCGTG GCATGGGTGC CCAAGTACTC CGGCGTGTCT 
CCCCGGGACA AGTGCAAGCT CATCTGCCGA GCCAATGGCA CTGGCTACTT CTATGTGCTG 
GCACCCAAGG TGGTGGACGG CACGCTGTGC TCTCCTGACT CCACCTCCGT CTGTGTCCAA 
GGCAAGTGCA TCAAGGCTGG CTGTGATGGG AACCTGGGCT CCAAGAAGAG ATTCGACAAG 
TGTGGGGTGT GTGGGGGAGA CAATAAGAGC TGCAAGAAGG TGACTGGACT CTTCACCAAG 
CCCATGCATG GCTACAATTT CGTGGTGGCC ATCCCCGCAG GCGCCTCAAG CATCGACATC 
CGCCAGCGCG GTTACAAAGG GCTGATCGGG GATGACAACT ACCTGGCTCT GAAGAACAGC 
CAAGGCAAGT ACCTGCTCAA CGGGCATTTC GTGGTGTCGG CGGTGGAGCG GGACCTGGTG 
GTGAAGGGCA GTCTGCTGCG GTACAGCGGC ACGGGCACAG CGGTGGAGAG CCTGCAGGCT 
TCCCGGCCCA TCCTGGAGCC GCTGACCGTG GAGGTCCTCT CCGTGGGGAA GATGACACCG 
CCCCGGGTCC GCTACTCCTT CTATCTGCCC AAAGAGCCTC GGGAGGACAA GTCCTCTCAT 
CCCAAGGACC CCCGGGGACC CTCTGTCTTG CACAACAGCG TCCTCAGCCT CTCCAACCAG 
GTGGAGCAGC CGGACGACAG GCCCCCTGCA CGCTGGGTGG CTGGCAGCTG GGGGCCGTGC 
TCCGCGAGCT GCGGCAGTGG CCTGCAGAAG CGGGCGGTGG ACTGCCGGGG CTCCGCCGGG 
CAGCGCACGG TCCCTGCCTG TGATGCAGCC CATCGGCCCG TGGAGACACA AGCCTGCGGG 
GAGCCCTGCC CCACCTGGGA GCTCAGCGCC TGGTCACCCT GCTCCAAGAG CTGCGGCCGG 
GGATTTCAGA GGCGCTCACT CAAGTGTGTG GGCCACGGAG GCCGGCTGCT GGCCCGGGAC 
CAGTGCAACT TGCACCGCAA GCCCCAGGAG CTGGACTTCT GCGTCCTGAG GCCGTGCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_005271476.1
CDS	278..2137
Translation	MADVGTMCDPKRSCSVIEDDGLPSAFTTAHELGHVFNMPHDNVKVCEEVFGKLRANHMMSPTLIQIDRANPWSACSAAIITDFLDSGHGDCLLDQPSKPISLPEDLPGASYTLSQQCELAFGVGSKPCPYMQYCTKLWCTGKAKGQMVCQTRHFPWADGTSCGEGKLCLKGACVERHNLNKHRVDGSWAKWDPYGPCSRTCGGGVQLARRQCTNPTPANGGKYCEGVRVKYRSCNLEPCPSSASGKSFREEQCEAFNGYNHSTNRLTLAVAWVPKYSGVSPRDKCKLICRANGTGYFYVLAPKVVDGTLCSPDSTSVCVQGKCIKAGCDGNLGSKKRFDKCGVCGGDNKSCKKVTGLFTKPMHGYNFVVAIPAGASSIDIRQRGYKGLIGDDNYLALKNSQGKYLLNGHFVVSAVERDLVVKGSLLRYSGTGTAVESLQASRPILEPLTVEVLSVGKMTPPRVRYSFYLPKEPREDKSSHPKDPRGPSVLHNSVLSLSNQVEQPDDRPPARWVAGSWGPCSASCGSGLQKRAVDCRGSAGQRTVPACDAAHRPVETQACGEPCPTWELSAWSPCSKSCGRGFQRRSLKCVGHGGRLLARDQCNLHRKPQELDFCVLRPC

Target ORF information:

RefSeq Version	XM_005271419.4
Organism	Homo sapiens(human)
Definition	Homo sapiens ADAM metallopeptidase with thrombospondin type 1 motif 15 (ADAMTS15), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_005271419.4

ORF Insert Sequence:

ATGGCTGATG TGGGTACCAT GTGTGACCCC AAGAGAAGCT GCTCTGTCAT TGAGGACGAT 
GGGCTTCCAT CAGCCTTCAC CACTGCCCAC GAGCTGGGCC ACGTGTTCAA CATGCCCCAT 
GACAATGTGA AAGTCTGTGA GGAGGTGTTT GGGAAGCTCC GAGCCAACCA CATGATGTCC 
CCGACCCTCA TCCAGATCGA CCGTGCCAAC CCCTGGTCAG CCTGCAGTGC TGCCATCATC 
ACCGACTTCC TGGACAGCGG GCACGGTGAC TGCCTCCTGG ACCAACCCAG CAAGCCCATC 
TCCCTGCCCG AGGATCTGCC GGGCGCCAGC TACACCCTGA GCCAGCAGTG CGAGCTGGCT 
TTTGGCGTGG GCTCCAAGCC CTGTCCTTAC ATGCAGTACT GCACCAAGCT GTGGTGCACC 
GGGAAGGCCA AGGGACAGAT GGTGTGCCAG ACCCGCCACT TCCCCTGGGC CGATGGCACC 
AGCTGTGGCG AGGGCAAGCT CTGCCTCAAA GGGGCCTGCG TGGAGAGACA CAACCTCAAC 
AAGCACAGGG TGGATGGTTC CTGGGCCAAA TGGGATCCCT ATGGCCCCTG CTCGCGCACA 
TGTGGTGGGG GCGTGCAGCT GGCCAGGAGG CAGTGCACCA ACCCCACCCC TGCCAACGGG 
GGCAAGTACT GCGAGGGAGT GAGGGTGAAA TACCGATCCT GCAATCTGGA GCCCTGCCCC 
AGCTCAGCCT CCGGAAAGAG CTTCCGGGAG GAGCAGTGTG AGGCTTTCAA CGGCTACAAC 
CACAGCACCA ACCGGCTCAC TCTCGCCGTG GCATGGGTGC CCAAGTACTC CGGCGTGTCT 
CCCCGGGACA AGTGCAAGCT CATCTGCCGA GCCAATGGCA CTGGCTACTT CTATGTGCTG 
GCACCCAAGG TGGTGGACGG CACGCTGTGC TCTCCTGACT CCACCTCCGT CTGTGTCCAA 
GGCAAGTGCA TCAAGGCTGG CTGTGATGGG AACCTGGGCT CCAAGAAGAG ATTCGACAAG 
TGTGGGGTGT GTGGGGGAGA CAATAAGAGC TGCAAGAAGG TGACTGGACT CTTCACCAAG 
CCCATGCATG GCTACAATTT CGTGGTGGCC ATCCCCGCAG GCGCCTCAAG CATCGACATC 
CGCCAGCGCG GTTACAAAGG GCTGATCGGG GATGACAACT ACCTGGCTCT GAAGAACAGC 
CAAGGCAAGT ACCTGCTCAA CGGGCATTTC GTGGTGTCGG CGGTGGAGCG GGACCTGGTG 
GTGAAGGGCA GTCTGCTGCG GTACAGCGGC ACGGGCACAG CGGTGGAGAG CCTGCAGGCT 
TCCCGGCCCA TCCTGGAGCC GCTGACCGTG GAGGTCCTCT CCGTGGGGAA GATGACACCG 
CCCCGGGTCC GCTACTCCTT CTATCTGCCC AAAGAGCCTC GGGAGGACAA GTCCTCTCAT 
CCCAAGGACC CCCGGGGACC CTCTGTCTTG CACAACAGCG TCCTCAGCCT CTCCAACCAG 
GTGGAGCAGC CGGACGACAG GCCCCCTGCA CGCTGGGTGG CTGGCAGCTG GGGGCCGTGC 
TCCGCGAGCT GCGGCAGTGG CCTGCAGAAG CGGGCGGTGG ACTGCCGGGG CTCCGCCGGG 
CAGCGCACGG TCCCTGCCTG TGATGCAGCC CATCGGCCCG TGGAGACACA AGCCTGCGGG 
GAGCCCTGCC CCACCTGGGA GCTCAGCGCC TGGTCACCCT GCTCCAAGAG CTGCGGCCGG 
GGATTTCAGA GGCGCTCACT CAAGTGTGTG GGCCACGGAG GCCGGCTGCT GGCCCGGGAC 
CAGTGCAACT TGCACCGCAA GCCCCAGGAG CTGGACTTCT GCGTCCTGAG GCCGTGCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Versican Proteolysis by ADAMTS Proteases and Its Influence on Sex Steroid Receptor Expression in Uterine Leiomyoma.
The Journal of clinical endocrinology and metabolism102(5)1631-1641(2017 May)
Gueye NA,Mead TJ,Koch CD,Biscotti CV,Falcone T,Apte SS

Human gingiva transcriptome during wound healing.
Journal of clinical periodontology44(4)394-402(2017 Apr)
Wang Y,Tatakis DN

ADAMTS13 and 15 are not regulated by the full length and N-terminal domain forms of TIMP-1, -2, -3 and -4.
Biomedical reports4(1)73-78(2016 Jan)
Guo C,Tsigkou A,Lee MH

Genetic study of intracranial aneurysms.
Stroke46(3)620-6(2015 Mar)
Yan J,Hitomi T,Takenaka K,Kato M,Kobayashi H,Okuda H,Harada KH,Koizumi A

Metalloproteinase-dependent and -independent processes contribute to inhibition of breast cancer cell migration, angiogenesis and liver metastasis by a disintegrin and metalloproteinase with thrombospondin motifs-15.
International journal of cancer136(4)E14-26(2015 Feb)
Kelwick R,Wagstaff L,Decock J,Roghi C,Cooley LS,Robinson SD,Arnold H,Gavrilovi? J,Jaworski DM,Yamamoto K,Nagase H,Seubert B,Kr?ger A,Edwards DR

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ADAMTS15 cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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