LCA5 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	LCA5
Entrez Gene ID	167691
Full Name	LCA5, lebercilin
Synonyms	C6orf152
General protein information	Preferred Names LCA5, lebercilin Names lebercilin leber congenital amaurosis 5 protein
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 6 Map Location: 6q14.1
Summary	This gene encodes a protein that is thought to be involved in centrosomal or ciliary functions. Mutations in this gene cause Leber congenital amaurosis type V. Alternatively spliced transcript variants are described. [provided by RefSeq, Oct 2009].
Disorder MIM:	611408
Disorder Html:	Leber congenital amaurosis 5, 604537 (3)

mRNA and Protein(s)

mRNA	Protein	Name
XM_005248665.3	XP_005248722.1	lebercilin isoform X1
NM_001122769.2	NP_001116241.1	lebercilin
XM_011535504.1	XP_011533806.1	lebercilin isoform X1
XM_005248665.4	XP_005248722.1	lebercilin isoform X1
NM_001122769.3	NP_001116241.1	lebercilin
NM_181714.3	NP_859065.2	lebercilin
NM_181714.4	NP_859065.2	lebercilin

Pathways from BioSystems

Homologies

Homo sapiens (human)	LCA5	NP_001116241.1
Gallus gallus (chicken)	LCA5	XP_419870.1
Danio rerio (zebrafish)	lca5	XP_001919911.2
Xenopus tropicalis (tropical clawed frog)	lca5	XP_002936257.2
Pan troglodytes (chimpanzee)	LCA5	XP_001146093.1
	LCA5	XP_001113860.1
Canis lupus familiaris (dog)	LCA5	XP_005627619.1
Mus musculus (house mouse)	Lca5	NP_081724.1
Xenopus tropicalis (tropical clawed frog)	LOC100497171	XP_002937268.1
Bos taurus (cattle)	LCA5	XP_005210747.1
Rattus norvegicus (Norway rat)	Lca5	NP_001013976.1

Gene Ontology
Bibliography

Related articles in PubMed

Architecture of the human interactome defines protein communities and disease networks.
Huttlin EL, Bruckner RJ, Paulo JA, Cannon JR, Ting L, Baltier K, Colby G, Gebreab F, Gygi MP, Parzen H, Szpyt J, Tam S, Zarraga G, Pontano-Vaites L, Swarup S, White AE, Schweppe DK, Rad R, Erickson BK, Obar RA, Guruharsha KG, Li K, Artavanis-Tsakonas S, Gygi SP, Harper JW
Nature545(7655)505-509(2017 05)

An organelle-specific protein landscape identifies novel diseases and molecular mechanisms.
Boldt K, van Reeuwijk J, Lu Q, Koutroumpas K, Nguyen TM, Texier Y, van Beersum SE, Horn N, Willer JR, Mans DA, Dougherty G, Lamers IJ, Coene KL, Arts HH, Betts MJ, Beyer T, Bolat E, Gloeckner CJ, Haidari K, Hetterschijt L, Iaconis D, Jenkins D, Klose F, Knapp B, Latour B, Letteboer SJ, Marcelis CL, Mitic D, Morleo M, Oud MM, Riemersma M, Rix S, Terhal PA, Toedt G, van Dam TJ, de Vrieze E, Wissinger Y, Wu KM, Apic G, Beales PL, Blacque OE, Gibson TJ, Huynen MA, Katsanis N, Kremer H, Omran H, van Wijk E, Wolfrum U, Kepes F, Davis EE, Franco B, Giles RH, Ueffing M, Russell RB, Roepman R,
Nature communications711491(2016 May)

Next-generation Sequencing Extends the Phenotypic Spectrum for LCA5 Mutations: Novel LCA5 Mutations in Cone Dystrophy.
Chen X, Sheng X, Sun X, Zhang Y, Jiang C, Li H, Ding S, Liu Y, Liu W, Li Z, Zhao C
Scientific reports624357(2016 Apr)

A Dynamic Protein Interaction Landscape of the Human Centrosome-Cilium Interface.
Gupta GD, Coyaud ?, Gon?alves J, Mojarad BA, Liu Y, Wu Q, Gheiratmand L, Comartin D, Tkach JM, Cheung SW, Bashkurov M, Hasegan M, Knight JD, Lin ZY, Schueler M, Hildebrandt F, Moffat J, Gingras AC, Raught B, Pelletier L
Cell163(6)1484-99(2015 Dec)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The authors report novel biallelic LCA5 mutations, Ala212Pro and Tyr441Cys, as causing cone dystrophy.
Title: Next-generation Sequencing Extends the Phenotypic Spectrum for LCA5 Mutations: Novel LCA5 Mutations in Cone Dystrophy.

This work reveals a higher frequency of LCA5 mutations in a Spanish Leber congenital amaurosis cohort than in other populations.
Title: Involvement of LCA5 in Leber congenital amaurosis and retinitis pigmentosa in the Spanish population.

Identification of novel LCA5 mutations in patients with Leber congenital amaurosis and retinitis pigmentosa.
Title: Screening of a large cohort of leber congenital amaurosis and retinitis pigmentosa patients identifies novel LCA5 mutations and new genotype-phenotype correlations.

A novel LCA5 mutation is present in a Pakistani family with Leber congenital amaurosis and cataracts.
Title: Identification of a novel LCA5 mutation in a Pakistani family with Leber congenital amaurosis and cataracts.

OFD1 is mutated in X-linked Joubert syndrome and interacts with LCA5-encoded lebercilin
Title: OFD1 is mutated in X-linked Joubert syndrome and interacts with LCA5-encoded lebercilin.

The following LCA5 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the LCA5 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu16637	NM_181714.4 Latest version!	Homo sapiens lebercilin LCA5 (LCA5), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$189.50-$265.30 $379.00
OHu16637	NM_001122769.3 Latest version!	Homo sapiens lebercilin LCA5 (LCA5), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$189.50-$265.30 $379.00
OHu16637	XM_005248665.4 Latest version!	Homo sapiens lebercilin LCA5 (LCA5), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$189.50-$265.30 $379.00
OHu16637	XM_011535504.1 Latest version!	Homo sapiens lebercilin LCA5 (LCA5), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$189.50-$265.30 $379.00
View Old Accession Versions >>
OHu16637	XM_005248665.3	Homo sapiens Leber congenital amaurosis 5 (LCA5), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$189.50-$265.30 $379.00
OHu16637	NM_001122769.2	Homo sapiens LCA5, lebercilin (LCA5), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$189.50-$265.30 $379.00
OHu16637	NM_181714.3	Homo sapiens lebercilin LCA5 (LCA5), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$189.50-$265.30 $379.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

LCA5 ( NM_001122769.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_001116241.1 Homo sapiens LCA5, lebercilin (LCA5), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu16637
Clone ID Related Accession (Same CDS sequence)	XM_005248665.3 , NM_001122769.2 , XM_011535504.1 , XM_005248665.4 , NM_001122769.3 , NM_181714.3 , NM_181714.4
Accession Version	NM_001122769.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2094bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-10-01
Organism	Homo sapiens(human)
Product	lebercilin
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BC050327.1, BX648161.1, BE883302.1 and AL832214.1. On Nov 4, 2009 this sequence version replaced NM_001122769.1. Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 1. Both variants 1 and 2 encode the same protein. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BX648161.1, SRR1660805.108851.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968189, SAMEA1968540 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGGGGAAA GAGCAGGAAG TCCAGGTACT GATCAAGAAA GAAAGGCAGG CAAACACCAT 
TATTCTTACT TATCTGATTT TGAAACGCCA CAGTCTTCTG GCCGATCATC GCTGGTCAGT 
TCTTCACCTG CAAGTGTTAG GAGAAAAAAT CCTAAAAGAC AAACTTCAGA TGGCCAAGTA 
CATCACCAAG CCCCTCGGAA ACCAAGCCCT AAGGGTCTAC CAAACAGAAA GGGAGTCCGA 
GTGGGATTTC GCTCCCAGAG CCTCAATAGA GAGCCACTTC GGAAAGATAC TGATCTTGTT 
ACAAAACGGA TTCTGTCTGC AAGACTGCTA AAAATCAATG AGTTGCAGAA TGAAGTATCT 
GAACTCCAGG TCAAGTTAGC TGAGCTGCTA AAAGAAAATA AATCTTTGAA AAGGCTTCAG 
TACAGACAGG AGAAAGCCCT GAATAAGTTT GAAGATGCCG AAAATGAAAT CTCACAACTT 
ATATTTCGTC ATAACAATGA GATTACAGCA CTCAAAGAAC GCTTAAGAAA ATCTCAAGAG 
AAAGAACGGG CAACTGAGAA AAGGGTAAAA GATACAGAAA GTGAACTATT TAGGACAAAA 
TTTTCCTTAC AGAAACTGAA AGAGATCTCT GAAGCTAGAC ACCTACCTGA ACGAGATGAT 
TTGGCAAAGA AACTAGTTTC AGCAGAGTTA AAGTTAGATG ACACCGAGAG AAGAATTAAG 
GAGCTATCGA AAAACCTTGA ACTGAGTACT AACAGTTTCC AACGACAGTT GCTTGCTGAA 
AGGAAAAGGG CATATGAGGC TCATGATGAA AATAAAGTTC TTCAAAAGGA GGTACAGCGA 
CTATATCACA AATTAAAGGA AAAGGAGAGA GAACTGGATA TAAAAAATAT ATATTCTAAT 
CGTCTGCCAA AGTCCTCTCC AAATAAAGAG AAAGAACTTG CATTAAGAAA AAATGCTGCA 
TGCCAGAGTG ATTTTGCAGA CCTGTGTACA AAAGGAGTAC AAACCATGGA AGACTTCAAG 
CCAGAAGAAT ATCCTTTAAC TCCAGAAACA ATTATGTGTT ACGAAAACAA ATGGGAAGAA 
CCAGGACATC TTACTTTGGA CTTGCAATCT CAAAAGCAAG ACAGGCATGG AGAAGCAGGG 
ATTCTAAACC CAATTATGGA AAGAGAAGAA AAATTTGTTA CAGATGAAGA ACTCCATGTC 
GTAAAACAGG AGGTTGAAAA GCTGGAGGAT GAATGGGAAA GAGAAGAACT TGATAAAAAG 
CAAAAAGAAA AGGCATCTTT ACTGGAAAGA GAAGAAAAGC CAGAGTGGGA AACTGGAAGG 
TACCAACTAG GAATGTATCC AATTCAGAAT ATGGATAAAT TGCAAGGAGA GGAAGAAGAA 
AGACTGAAGA GAGAAATGCT ACTTGCTAAA CTGAATGAAA TTGACAGAGA ACTCCAAGAT 
TCTCGAAATC TAAAATACCC TGTTTTGCCA TTGTTACCTG ATTTTGAATC AAAACTACAC 
TCCCCAGAGA GAAGCCCCAA AACATACAGG TTCTCTGAAT CCTCAGAGAG ATTATTTAAT 
GGGCATCATT TGCAAGACAT CAGTTTCTCA ACTCCAAAAG GAGAAGGTCA GAATTCAGGA 
AATGTTAGAA GTCCAGCCTC CCCTAATGAG TTCGCATTTG GTAGCTACGT GCCTTCGTTT 
GCAAAAACAT CAGAGAGGTC AAATCCATTT AGTCAAAAAA GTAGTTTTTT GGATTTCCAA 
AGAAACAGTA TGGAAAAACT TAGTAAAGAT GGTGTAGATT TAATTACAAG AAAAGAGAAA 
AAAGCTAATT TGATGGAACA GTTATTTGGT GCCAGTGGTA GCAGCACCAT TTCCTCCAAA 
AGCAGTGACC CAAATTCTGT GGCTTCCAGT AAAGGAGACA TTGACCCTCT AAATTTTCTC 
CCTGGGAATA AAGGCAGCAG AGATCAAGAA CATGATGAAG ATGAAGGCTT TTTCCTCAGT 
GAAGGAAGAA GTTTTAATCC AAATAGGCAC CGATTAAAAC ATGCAGACGA TAAACCAGCA 
GTAAAAGCAG CTGATTCTGT AGAAGATGAA ATTGAAGAAG TAGCACTGAG ATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001116241.1
CDS	458..2551
Translation	MGERAGSPGTDQERKAGKHHYSYLSDFETPQSSGRSSLVSSSPASVRRKNPKRQTSDGQVHHQAPRKPSPKGLPNRKGVRVGFRSQSLNREPLRKDTDLVTKRILSARLLKINELQNEVSELQVKLAELLKENKSLKRLQYRQEKALNKFEDAENEISQLIFRHNNEITALKERLRKSQEKERATEKRVKDTESELFRTKFSLQKLKEISEARHLPERDDLAKKLVSAELKLDDTERRIKELSKNLELSTNSFQRQLLAERKRAYEAHDENKVLQKEVQRLYHKLKEKERELDIKNIYSNRLPKSSPNKEKELALRKNAACQSDFADLCTKGVQTMEDFKPEEYPLTPETIMCYENKWEEPGHLTLDLQSQKQDRHGEAGILNPIMEREEKFVTDEELHVVKQEVEKLEDEWEREELDKKQKEKASLLEREEKPEWETGRYQLGMYPIQNMDKLQGEEEERLKREMLLAKLNEIDRELQDSRNLKYPVLPLLPDFESKLHSPERSPKTYRFSESSERLFNGHHLQDISFSTPKGEGQNSGNVRSPASPNEFAFGSYVPSFAKTSERSNPFSQKSSFLDFQRNSMEKLSKDGVDLITRKEKKANLMEQLFGASGSSTISSKSSDPNSVASSKGDIDPLNFLPGNKGSRDQEHDEDEGFFLSEGRSFNPNRHRLKHADDKPAVKAADSVEDEIEEVALR

Target ORF information:

RefSeq Version	NM_001122769.2
Organism	Homo sapiens(human)
Definition	Homo sapiens LCA5, lebercilin (LCA5), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001122769.2

ORF Insert Sequence:

ATGGGGGAAA GAGCAGGAAG TCCAGGTACT GATCAAGAAA GAAAGGCAGG CAAACACCAT 
TATTCTTACT TATCTGATTT TGAAACGCCA CAGTCTTCTG GCCGATCATC GCTGGTCAGT 
TCTTCACCTG CAAGTGTTAG GAGAAAAAAT CCTAAAAGAC AAACTTCAGA TGGCCAAGTA 
CATCACCAAG CCCCTCGGAA ACCAAGCCCT AAGGGTCTAC CAAACAGAAA GGGAGTCCGA 
GTGGGATTTC GCTCCCAGAG CCTCAATAGA GAGCCACTTC GGAAAGATAC TGATCTTGTT 
ACAAAACGGA TTCTGTCTGC AAGACTGCTA AAAATCAATG AGTTGCAGAA TGAAGTATCT 
GAACTCCAGG TCAAGTTAGC TGAGCTGCTA AAAGAAAATA AATCTTTGAA AAGGCTTCAG 
TACAGACAGG AGAAAGCCCT GAATAAGTTT GAAGATGCCG AAAATGAAAT CTCACAACTT 
ATATTTCGTC ATAACAATGA GATTACAGCA CTCAAAGAAC GCTTAAGAAA ATCTCAAGAG 
AAAGAACGGG CAACTGAGAA AAGGGTAAAA GATACAGAAA GTGAACTATT TAGGACAAAA 
TTTTCCTTAC AGAAACTGAA AGAGATCTCT GAAGCTAGAC ACCTACCTGA ACGAGATGAT 
TTGGCAAAGA AACTAGTTTC AGCAGAGTTA AAGTTAGATG ACACCGAGAG AAGAATTAAG 
GAGCTATCGA AAAACCTTGA ACTGAGTACT AACAGTTTCC AACGACAGTT GCTTGCTGAA 
AGGAAAAGGG CATATGAGGC TCATGATGAA AATAAAGTTC TTCAAAAGGA GGTACAGCGA 
CTATATCACA AATTAAAGGA AAAGGAGAGA GAACTGGATA TAAAAAATAT ATATTCTAAT 
CGTCTGCCAA AGTCCTCTCC AAATAAAGAG AAAGAACTTG CATTAAGAAA AAATGCTGCA 
TGCCAGAGTG ATTTTGCAGA CCTGTGTACA AAAGGAGTAC AAACCATGGA AGACTTCAAG 
CCAGAAGAAT ATCCTTTAAC TCCAGAAACA ATTATGTGTT ACGAAAACAA ATGGGAAGAA 
CCAGGACATC TTACTTTGGA CTTGCAATCT CAAAAGCAAG ACAGGCATGG AGAAGCAGGG 
ATTCTAAACC CAATTATGGA AAGAGAAGAA AAATTTGTTA CAGATGAAGA ACTCCATGTC 
GTAAAACAGG AGGTTGAAAA GCTGGAGGAT GAATGGGAAA GAGAAGAACT TGATAAAAAG 
CAAAAAGAAA AGGCATCTTT ACTGGAAAGA GAAGAAAAGC CAGAGTGGGA AACTGGAAGG 
TACCAACTAG GAATGTATCC AATTCAGAAT ATGGATAAAT TGCAAGGAGA GGAAGAAGAA 
AGACTGAAGA GAGAAATGCT ACTTGCTAAA CTGAATGAAA TTGACAGAGA ACTCCAAGAT 
TCTCGAAATC TAAAATACCC TGTTTTGCCA TTGTTACCTG ATTTTGAATC AAAACTACAC 
TCCCCAGAGA GAAGCCCCAA AACATACAGG TTCTCTGAAT CCTCAGAGAG ATTATTTAAT 
GGGCATCATT TGCAAGACAT CAGTTTCTCA ACTCCAAAAG GAGAAGGTCA GAATTCAGGA 
AATGTTAGAA GTCCAGCCTC CCCTAATGAG TTCGCATTTG GTAGCTACGT GCCTTCGTTT 
GCAAAAACAT CAGAGAGGTC AAATCCATTT AGTCAAAAAA GTAGTTTTTT GGATTTCCAA 
AGAAACAGTA TGGAAAAACT TAGTAAAGAT GGTGTAGATT TAATTACAAG AAAAGAGAAA 
AAAGCTAATT TGATGGAACA GTTATTTGGT GCCAGTGGTA GCAGCACCAT TTCCTCCAAA 
AGCAGTGACC CAAATTCTGT GGCTTCCAGT AAAGGAGACA TTGACCCTCT AAATTTTCTC 
CCTGGGAATA AAGGCAGCAG AGATCAAGAA CATGATGAAG ATGAAGGCTT TTTCCTCAGT 
GAAGGAAGAA GTTTTAATCC AAATAGGCAC CGATTAAAAC ATGCAGACGA TAAACCAGCA 
GTAAAAGCAG CTGATTCTGT AGAAGATGAA ATTGAAGAAG TAGCACTGAG ATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

LCA5 ( NM_001122769.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_001116241.1 Homo sapiens lebercilin LCA5 (LCA5), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu16637
Clone ID Related Accession (Same CDS sequence)	XM_005248665.3 , NM_001122769.2 , XM_011535504.1 , XM_005248665.4 , NM_001122769.3 , NM_181714.3 , NM_181714.4
Accession Version	NM_001122769.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2094bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-10-10
Organism	Homo sapiens(human)
Product	lebercilin
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BC050327.1, BX648161.1, BE883302.1 and AL832214.1. On Nov 23, 2018 this sequence version replaced NM_001122769.2. Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 1. Both variants 1 and 2 encode the same protein. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BX648161.1, SRR1660805.108851.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968189, SAMEA1968540 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000369846.9/ ENSP00000358861.4 RefSeq Select criteria :: based on conservation, expression, longest protein ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGGGGGAAA GAGCAGGAAG TCCAGGTACT GATCAAGAAA GAAAGGCAGG CAAACACCAT 
TATTCTTACT TATCTGATTT TGAAACGCCA CAGTCTTCTG GCCGATCATC GCTGGTCAGT 
TCTTCACCTG CAAGTGTTAG GAGAAAAAAT CCTAAAAGAC AAACTTCAGA TGGCCAAGTA 
CATCACCAAG CCCCTCGGAA ACCAAGCCCT AAGGGTCTAC CAAACAGAAA GGGAGTCCGA 
GTGGGATTTC GCTCCCAGAG CCTCAATAGA GAGCCACTTC GGAAAGATAC TGATCTTGTT 
ACAAAACGGA TTCTGTCTGC AAGACTGCTA AAAATCAATG AGTTGCAGAA TGAAGTATCT 
GAACTCCAGG TCAAGTTAGC TGAGCTGCTA AAAGAAAATA AATCTTTGAA AAGGCTTCAG 
TACAGACAGG AGAAAGCCCT GAATAAGTTT GAAGATGCCG AAAATGAAAT CTCACAACTT 
ATATTTCGTC ATAACAATGA GATTACAGCA CTCAAAGAAC GCTTAAGAAA ATCTCAAGAG 
AAAGAACGGG CAACTGAGAA AAGGGTAAAA GATACAGAAA GTGAACTATT TAGGACAAAA 
TTTTCCTTAC AGAAACTGAA AGAGATCTCT GAAGCTAGAC ACCTACCTGA ACGAGATGAT 
TTGGCAAAGA AACTAGTTTC AGCAGAGTTA AAGTTAGATG ACACCGAGAG AAGAATTAAG 
GAGCTATCGA AAAACCTTGA ACTGAGTACT AACAGTTTCC AACGACAGTT GCTTGCTGAA 
AGGAAAAGGG CATATGAGGC TCATGATGAA AATAAAGTTC TTCAAAAGGA GGTACAGCGA 
CTATATCACA AATTAAAGGA AAAGGAGAGA GAACTGGATA TAAAAAATAT ATATTCTAAT 
CGTCTGCCAA AGTCCTCTCC AAATAAAGAG AAAGAACTTG CATTAAGAAA AAATGCTGCA 
TGCCAGAGTG ATTTTGCAGA CCTGTGTACA AAAGGAGTAC AAACCATGGA AGACTTCAAG 
CCAGAAGAAT ATCCTTTAAC TCCAGAAACA ATTATGTGTT ACGAAAACAA ATGGGAAGAA 
CCAGGACATC TTACTTTGGA CTTGCAATCT CAAAAGCAAG ACAGGCATGG AGAAGCAGGG 
ATTCTAAACC CAATTATGGA AAGAGAAGAA AAATTTGTTA CAGATGAAGA ACTCCATGTC 
GTAAAACAGG AGGTTGAAAA GCTGGAGGAT GAATGGGAAA GAGAAGAACT TGATAAAAAG 
CAAAAAGAAA AGGCATCTTT ACTGGAAAGA GAAGAAAAGC CAGAGTGGGA AACTGGAAGG 
TACCAACTAG GAATGTATCC AATTCAGAAT ATGGATAAAT TGCAAGGAGA GGAAGAAGAA 
AGACTGAAGA GAGAAATGCT ACTTGCTAAA CTGAATGAAA TTGACAGAGA ACTCCAAGAT 
TCTCGAAATC TAAAATACCC TGTTTTGCCA TTGTTACCTG ATTTTGAATC AAAACTACAC 
TCCCCAGAGA GAAGCCCCAA AACATACAGG TTCTCTGAAT CCTCAGAGAG ATTATTTAAT 
GGGCATCATT TGCAAGACAT CAGTTTCTCA ACTCCAAAAG GAGAAGGTCA GAATTCAGGA 
AATGTTAGAA GTCCAGCCTC CCCTAATGAG TTCGCATTTG GTAGCTACGT GCCTTCGTTT 
GCAAAAACAT CAGAGAGGTC AAATCCATTT AGTCAAAAAA GTAGTTTTTT GGATTTCCAA 
AGAAACAGTA TGGAAAAACT TAGTAAAGAT GGTGTAGATT TAATTACAAG AAAAGAGAAA 
AAAGCTAATT TGATGGAACA GTTATTTGGT GCCAGTGGTA GCAGCACCAT TTCCTCCAAA 
AGCAGTGACC CAAATTCTGT GGCTTCCAGT AAAGGAGACA TTGACCCTCT AAATTTTCTC 
CCTGGGAATA AAGGCAGCAG AGATCAAGAA CATGATGAAG ATGAAGGCTT TTTCCTCAGT 
GAAGGAAGAA GTTTTAATCC AAATAGGCAC CGATTAAAAC ATGCAGACGA TAAACCAGCA 
GTAAAAGCAG CTGATTCTGT AGAAGATGAA ATTGAAGAAG TAGCACTGAG ATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001116241.1
CDS	458..2551
Translation	MGERAGSPGTDQERKAGKHHYSYLSDFETPQSSGRSSLVSSSPASVRRKNPKRQTSDGQVHHQAPRKPSPKGLPNRKGVRVGFRSQSLNREPLRKDTDLVTKRILSARLLKINELQNEVSELQVKLAELLKENKSLKRLQYRQEKALNKFEDAENEISQLIFRHNNEITALKERLRKSQEKERATEKRVKDTESELFRTKFSLQKLKEISEARHLPERDDLAKKLVSAELKLDDTERRIKELSKNLELSTNSFQRQLLAERKRAYEAHDENKVLQKEVQRLYHKLKEKERELDIKNIYSNRLPKSSPNKEKELALRKNAACQSDFADLCTKGVQTMEDFKPEEYPLTPETIMCYENKWEEPGHLTLDLQSQKQDRHGEAGILNPIMEREEKFVTDEELHVVKQEVEKLEDEWEREELDKKQKEKASLLEREEKPEWETGRYQLGMYPIQNMDKLQGEEEERLKREMLLAKLNEIDRELQDSRNLKYPVLPLLPDFESKLHSPERSPKTYRFSESSERLFNGHHLQDISFSTPKGEGQNSGNVRSPASPNEFAFGSYVPSFAKTSERSNPFSQKSSFLDFQRNSMEKLSKDGVDLITRKEKKANLMEQLFGASGSSTISSKSSDPNSVASSKGDIDPLNFLPGNKGSRDQEHDEDEGFFLSEGRSFNPNRHRLKHADDKPAVKAADSVEDEIEEVALR

Target ORF information:

RefSeq Version	NM_001122769.3
Organism	Homo sapiens(human)
Definition	Homo sapiens lebercilin LCA5 (LCA5), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001122769.3

ORF Insert Sequence:

ATGGGGGAAA GAGCAGGAAG TCCAGGTACT GATCAAGAAA GAAAGGCAGG CAAACACCAT 
TATTCTTACT TATCTGATTT TGAAACGCCA CAGTCTTCTG GCCGATCATC GCTGGTCAGT 
TCTTCACCTG CAAGTGTTAG GAGAAAAAAT CCTAAAAGAC AAACTTCAGA TGGCCAAGTA 
CATCACCAAG CCCCTCGGAA ACCAAGCCCT AAGGGTCTAC CAAACAGAAA GGGAGTCCGA 
GTGGGATTTC GCTCCCAGAG CCTCAATAGA GAGCCACTTC GGAAAGATAC TGATCTTGTT 
ACAAAACGGA TTCTGTCTGC AAGACTGCTA AAAATCAATG AGTTGCAGAA TGAAGTATCT 
GAACTCCAGG TCAAGTTAGC TGAGCTGCTA AAAGAAAATA AATCTTTGAA AAGGCTTCAG 
TACAGACAGG AGAAAGCCCT GAATAAGTTT GAAGATGCCG AAAATGAAAT CTCACAACTT 
ATATTTCGTC ATAACAATGA GATTACAGCA CTCAAAGAAC GCTTAAGAAA ATCTCAAGAG 
AAAGAACGGG CAACTGAGAA AAGGGTAAAA GATACAGAAA GTGAACTATT TAGGACAAAA 
TTTTCCTTAC AGAAACTGAA AGAGATCTCT GAAGCTAGAC ACCTACCTGA ACGAGATGAT 
TTGGCAAAGA AACTAGTTTC AGCAGAGTTA AAGTTAGATG ACACCGAGAG AAGAATTAAG 
GAGCTATCGA AAAACCTTGA ACTGAGTACT AACAGTTTCC AACGACAGTT GCTTGCTGAA 
AGGAAAAGGG CATATGAGGC TCATGATGAA AATAAAGTTC TTCAAAAGGA GGTACAGCGA 
CTATATCACA AATTAAAGGA AAAGGAGAGA GAACTGGATA TAAAAAATAT ATATTCTAAT 
CGTCTGCCAA AGTCCTCTCC AAATAAAGAG AAAGAACTTG CATTAAGAAA AAATGCTGCA 
TGCCAGAGTG ATTTTGCAGA CCTGTGTACA AAAGGAGTAC AAACCATGGA AGACTTCAAG 
CCAGAAGAAT ATCCTTTAAC TCCAGAAACA ATTATGTGTT ACGAAAACAA ATGGGAAGAA 
CCAGGACATC TTACTTTGGA CTTGCAATCT CAAAAGCAAG ACAGGCATGG AGAAGCAGGG 
ATTCTAAACC CAATTATGGA AAGAGAAGAA AAATTTGTTA CAGATGAAGA ACTCCATGTC 
GTAAAACAGG AGGTTGAAAA GCTGGAGGAT GAATGGGAAA GAGAAGAACT TGATAAAAAG 
CAAAAAGAAA AGGCATCTTT ACTGGAAAGA GAAGAAAAGC CAGAGTGGGA AACTGGAAGG 
TACCAACTAG GAATGTATCC AATTCAGAAT ATGGATAAAT TGCAAGGAGA GGAAGAAGAA 
AGACTGAAGA GAGAAATGCT ACTTGCTAAA CTGAATGAAA TTGACAGAGA ACTCCAAGAT 
TCTCGAAATC TAAAATACCC TGTTTTGCCA TTGTTACCTG ATTTTGAATC AAAACTACAC 
TCCCCAGAGA GAAGCCCCAA AACATACAGG TTCTCTGAAT CCTCAGAGAG ATTATTTAAT 
GGGCATCATT TGCAAGACAT CAGTTTCTCA ACTCCAAAAG GAGAAGGTCA GAATTCAGGA 
AATGTTAGAA GTCCAGCCTC CCCTAATGAG TTCGCATTTG GTAGCTACGT GCCTTCGTTT 
GCAAAAACAT CAGAGAGGTC AAATCCATTT AGTCAAAAAA GTAGTTTTTT GGATTTCCAA 
AGAAACAGTA TGGAAAAACT TAGTAAAGAT GGTGTAGATT TAATTACAAG AAAAGAGAAA 
AAAGCTAATT TGATGGAACA GTTATTTGGT GCCAGTGGTA GCAGCACCAT TTCCTCCAAA 
AGCAGTGACC CAAATTCTGT GGCTTCCAGT AAAGGAGACA TTGACCCTCT AAATTTTCTC 
CCTGGGAATA AAGGCAGCAG AGATCAAGAA CATGATGAAG ATGAAGGCTT TTTCCTCAGT 
GAAGGAAGAA GTTTTAATCC AAATAGGCAC CGATTAAAAC ATGCAGACGA TAAACCAGCA 
GTAAAAGCAG CTGATTCTGT AGAAGATGAA ATTGAAGAAG TAGCACTGAG ATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

LCA5 ( NM_181714.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_859065.2 Homo sapiens lebercilin LCA5 (LCA5), transcript variant 1, mRNA.

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CloneID	OHu16637
Clone ID Related Accession (Same CDS sequence)	XM_005248665.3 , NM_001122769.2 , XM_011535504.1 , XM_005248665.4 , NM_001122769.3 , NM_181714.3 , NM_181714.4
Accession Version	NM_181714.3	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2094bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-02-21
Organism	Homo sapiens(human)
Product	lebercilin
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BC050327.1, BE883302.1, AL832214.1 and BX648161.1. This sequence is a reference standard in the RefSeqGene project. On or before Aug 31, 2013 this sequence version replaced XM_005248664.1, NM_181714.2. Transcript Variant: This variant (1) represents the longer transcript. Both variants 1 and 2 encode the same protein. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC050327.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2144120, SAMEA2145240 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGGGGAAA GAGCAGGAAG TCCAGGTACT GATCAAGAAA GAAAGGCAGG CAAACACCAT 
TATTCTTACT TATCTGATTT TGAAACGCCA CAGTCTTCTG GCCGATCATC GCTGGTCAGT 
TCTTCACCTG CAAGTGTTAG GAGAAAAAAT CCTAAAAGAC AAACTTCAGA TGGCCAAGTA 
CATCACCAAG CCCCTCGGAA ACCAAGCCCT AAGGGTCTAC CAAACAGAAA GGGAGTCCGA 
GTGGGATTTC GCTCCCAGAG CCTCAATAGA GAGCCACTTC GGAAAGATAC TGATCTTGTT 
ACAAAACGGA TTCTGTCTGC AAGACTGCTA AAAATCAATG AGTTGCAGAA TGAAGTATCT 
GAACTCCAGG TCAAGTTAGC TGAGCTGCTA AAAGAAAATA AATCTTTGAA AAGGCTTCAG 
TACAGACAGG AGAAAGCCCT GAATAAGTTT GAAGATGCCG AAAATGAAAT CTCACAACTT 
ATATTTCGTC ATAACAATGA GATTACAGCA CTCAAAGAAC GCTTAAGAAA ATCTCAAGAG 
AAAGAACGGG CAACTGAGAA AAGGGTAAAA GATACAGAAA GTGAACTATT TAGGACAAAA 
TTTTCCTTAC AGAAACTGAA AGAGATCTCT GAAGCTAGAC ACCTACCTGA ACGAGATGAT 
TTGGCAAAGA AACTAGTTTC AGCAGAGTTA AAGTTAGATG ACACCGAGAG AAGAATTAAG 
GAGCTATCGA AAAACCTTGA ACTGAGTACT AACAGTTTCC AACGACAGTT GCTTGCTGAA 
AGGAAAAGGG CATATGAGGC TCATGATGAA AATAAAGTTC TTCAAAAGGA GGTACAGCGA 
CTATATCACA AATTAAAGGA AAAGGAGAGA GAACTGGATA TAAAAAATAT ATATTCTAAT 
CGTCTGCCAA AGTCCTCTCC AAATAAAGAG AAAGAACTTG CATTAAGAAA AAATGCTGCA 
TGCCAGAGTG ATTTTGCAGA CCTGTGTACA AAAGGAGTAC AAACCATGGA AGACTTCAAG 
CCAGAAGAAT ATCCTTTAAC TCCAGAAACA ATTATGTGTT ACGAAAACAA ATGGGAAGAA 
CCAGGACATC TTACTTTGGA CTTGCAATCT CAAAAGCAAG ACAGGCATGG AGAAGCAGGG 
ATTCTAAACC CAATTATGGA AAGAGAAGAA AAATTTGTTA CAGATGAAGA ACTCCATGTC 
GTAAAACAGG AGGTTGAAAA GCTGGAGGAT GAATGGGAAA GAGAAGAACT TGATAAAAAG 
CAAAAAGAAA AGGCATCTTT ACTGGAAAGA GAAGAAAAGC CAGAGTGGGA AACTGGAAGG 
TACCAACTAG GAATGTATCC AATTCAGAAT ATGGATAAAT TGCAAGGAGA GGAAGAAGAA 
AGACTGAAGA GAGAAATGCT ACTTGCTAAA CTGAATGAAA TTGACAGAGA ACTCCAAGAT 
TCTCGAAATC TAAAATACCC TGTTTTGCCA TTGTTACCTG ATTTTGAATC AAAACTACAC 
TCCCCAGAGA GAAGCCCCAA AACATACAGG TTCTCTGAAT CCTCAGAGAG ATTATTTAAT 
GGGCATCATT TGCAAGACAT CAGTTTCTCA ACTCCAAAAG GAGAAGGTCA GAATTCAGGA 
AATGTTAGAA GTCCAGCCTC CCCTAATGAG TTCGCATTTG GTAGCTACGT GCCTTCGTTT 
GCAAAAACAT CAGAGAGGTC AAATCCATTT AGTCAAAAAA GTAGTTTTTT GGATTTCCAA 
AGAAACAGTA TGGAAAAACT TAGTAAAGAT GGTGTAGATT TAATTACAAG AAAAGAGAAA 
AAAGCTAATT TGATGGAACA GTTATTTGGT GCCAGTGGTA GCAGCACCAT TTCCTCCAAA 
AGCAGTGACC CAAATTCTGT GGCTTCCAGT AAAGGAGACA TTGACCCTCT AAATTTTCTC 
CCTGGGAATA AAGGCAGCAG AGATCAAGAA CATGATGAAG ATGAAGGCTT TTTCCTCAGT 
GAAGGAAGAA GTTTTAATCC AAATAGGCAC CGATTAAAAC ATGCAGACGA TAAACCAGCA 
GTAAAAGCAG CTGATTCTGT AGAAGATGAA ATTGAAGAAG TAGCACTGAG ATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_859065.2
CDS	613..2706
Translation	MGERAGSPGTDQERKAGKHHYSYLSDFETPQSSGRSSLVSSSPASVRRKNPKRQTSDGQVHHQAPRKPSPKGLPNRKGVRVGFRSQSLNREPLRKDTDLVTKRILSARLLKINELQNEVSELQVKLAELLKENKSLKRLQYRQEKALNKFEDAENEISQLIFRHNNEITALKERLRKSQEKERATEKRVKDTESELFRTKFSLQKLKEISEARHLPERDDLAKKLVSAELKLDDTERRIKELSKNLELSTNSFQRQLLAERKRAYEAHDENKVLQKEVQRLYHKLKEKERELDIKNIYSNRLPKSSPNKEKELALRKNAACQSDFADLCTKGVQTMEDFKPEEYPLTPETIMCYENKWEEPGHLTLDLQSQKQDRHGEAGILNPIMEREEKFVTDEELHVVKQEVEKLEDEWEREELDKKQKEKASLLEREEKPEWETGRYQLGMYPIQNMDKLQGEEEERLKREMLLAKLNEIDRELQDSRNLKYPVLPLLPDFESKLHSPERSPKTYRFSESSERLFNGHHLQDISFSTPKGEGQNSGNVRSPASPNEFAFGSYVPSFAKTSERSNPFSQKSSFLDFQRNSMEKLSKDGVDLITRKEKKANLMEQLFGASGSSTISSKSSDPNSVASSKGDIDPLNFLPGNKGSRDQEHDEDEGFFLSEGRSFNPNRHRLKHADDKPAVKAADSVEDEIEEVALR

Target ORF information:

RefSeq Version	NM_181714.3
Organism	Homo sapiens(human)
Definition	Homo sapiens lebercilin LCA5 (LCA5), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_181714.3

ORF Insert Sequence:

ATGGGGGAAA GAGCAGGAAG TCCAGGTACT GATCAAGAAA GAAAGGCAGG CAAACACCAT 
TATTCTTACT TATCTGATTT TGAAACGCCA CAGTCTTCTG GCCGATCATC GCTGGTCAGT 
TCTTCACCTG CAAGTGTTAG GAGAAAAAAT CCTAAAAGAC AAACTTCAGA TGGCCAAGTA 
CATCACCAAG CCCCTCGGAA ACCAAGCCCT AAGGGTCTAC CAAACAGAAA GGGAGTCCGA 
GTGGGATTTC GCTCCCAGAG CCTCAATAGA GAGCCACTTC GGAAAGATAC TGATCTTGTT 
ACAAAACGGA TTCTGTCTGC AAGACTGCTA AAAATCAATG AGTTGCAGAA TGAAGTATCT 
GAACTCCAGG TCAAGTTAGC TGAGCTGCTA AAAGAAAATA AATCTTTGAA AAGGCTTCAG 
TACAGACAGG AGAAAGCCCT GAATAAGTTT GAAGATGCCG AAAATGAAAT CTCACAACTT 
ATATTTCGTC ATAACAATGA GATTACAGCA CTCAAAGAAC GCTTAAGAAA ATCTCAAGAG 
AAAGAACGGG CAACTGAGAA AAGGGTAAAA GATACAGAAA GTGAACTATT TAGGACAAAA 
TTTTCCTTAC AGAAACTGAA AGAGATCTCT GAAGCTAGAC ACCTACCTGA ACGAGATGAT 
TTGGCAAAGA AACTAGTTTC AGCAGAGTTA AAGTTAGATG ACACCGAGAG AAGAATTAAG 
GAGCTATCGA AAAACCTTGA ACTGAGTACT AACAGTTTCC AACGACAGTT GCTTGCTGAA 
AGGAAAAGGG CATATGAGGC TCATGATGAA AATAAAGTTC TTCAAAAGGA GGTACAGCGA 
CTATATCACA AATTAAAGGA AAAGGAGAGA GAACTGGATA TAAAAAATAT ATATTCTAAT 
CGTCTGCCAA AGTCCTCTCC AAATAAAGAG AAAGAACTTG CATTAAGAAA AAATGCTGCA 
TGCCAGAGTG ATTTTGCAGA CCTGTGTACA AAAGGAGTAC AAACCATGGA AGACTTCAAG 
CCAGAAGAAT ATCCTTTAAC TCCAGAAACA ATTATGTGTT ACGAAAACAA ATGGGAAGAA 
CCAGGACATC TTACTTTGGA CTTGCAATCT CAAAAGCAAG ACAGGCATGG AGAAGCAGGG 
ATTCTAAACC CAATTATGGA AAGAGAAGAA AAATTTGTTA CAGATGAAGA ACTCCATGTC 
GTAAAACAGG AGGTTGAAAA GCTGGAGGAT GAATGGGAAA GAGAAGAACT TGATAAAAAG 
CAAAAAGAAA AGGCATCTTT ACTGGAAAGA GAAGAAAAGC CAGAGTGGGA AACTGGAAGG 
TACCAACTAG GAATGTATCC AATTCAGAAT ATGGATAAAT TGCAAGGAGA GGAAGAAGAA 
AGACTGAAGA GAGAAATGCT ACTTGCTAAA CTGAATGAAA TTGACAGAGA ACTCCAAGAT 
TCTCGAAATC TAAAATACCC TGTTTTGCCA TTGTTACCTG ATTTTGAATC AAAACTACAC 
TCCCCAGAGA GAAGCCCCAA AACATACAGG TTCTCTGAAT CCTCAGAGAG ATTATTTAAT 
GGGCATCATT TGCAAGACAT CAGTTTCTCA ACTCCAAAAG GAGAAGGTCA GAATTCAGGA 
AATGTTAGAA GTCCAGCCTC CCCTAATGAG TTCGCATTTG GTAGCTACGT GCCTTCGTTT 
GCAAAAACAT CAGAGAGGTC AAATCCATTT AGTCAAAAAA GTAGTTTTTT GGATTTCCAA 
AGAAACAGTA TGGAAAAACT TAGTAAAGAT GGTGTAGATT TAATTACAAG AAAAGAGAAA 
AAAGCTAATT TGATGGAACA GTTATTTGGT GCCAGTGGTA GCAGCACCAT TTCCTCCAAA 
AGCAGTGACC CAAATTCTGT GGCTTCCAGT AAAGGAGACA TTGACCCTCT AAATTTTCTC 
CCTGGGAATA AAGGCAGCAG AGATCAAGAA CATGATGAAG ATGAAGGCTT TTTCCTCAGT 
GAAGGAAGAA GTTTTAATCC AAATAGGCAC CGATTAAAAC ATGCAGACGA TAAACCAGCA 
GTAAAAGCAG CTGATTCTGT AGAAGATGAA ATTGAAGAAG TAGCACTGAG ATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

LCA5 ( NM_181714.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_859065.2 Homo sapiens lebercilin LCA5 (LCA5), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu16637
Clone ID Related Accession (Same CDS sequence)	XM_005248665.3 , NM_001122769.2 , XM_011535504.1 , XM_005248665.4 , NM_001122769.3 , NM_181714.3 , NM_181714.4
Accession Version	NM_181714.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2094bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-10-10
Organism	Homo sapiens(human)
Product	lebercilin
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BC050327.1, BE883302.1, AL832214.1 and BX648161.1. This sequence is a reference standard in the RefSeqGene project. On May 31, 2019 this sequence version replaced NM_181714.3. Transcript Variant: This variant (1) represents the longer transcript. Both variants 1 and 2 encode the same protein. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC050327.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2144120, SAMEA2145240 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGGGGAAA GAGCAGGAAG TCCAGGTACT GATCAAGAAA GAAAGGCAGG CAAACACCAT 
TATTCTTACT TATCTGATTT TGAAACGCCA CAGTCTTCTG GCCGATCATC GCTGGTCAGT 
TCTTCACCTG CAAGTGTTAG GAGAAAAAAT CCTAAAAGAC AAACTTCAGA TGGCCAAGTA 
CATCACCAAG CCCCTCGGAA ACCAAGCCCT AAGGGTCTAC CAAACAGAAA GGGAGTCCGA 
GTGGGATTTC GCTCCCAGAG CCTCAATAGA GAGCCACTTC GGAAAGATAC TGATCTTGTT 
ACAAAACGGA TTCTGTCTGC AAGACTGCTA AAAATCAATG AGTTGCAGAA TGAAGTATCT 
GAACTCCAGG TCAAGTTAGC TGAGCTGCTA AAAGAAAATA AATCTTTGAA AAGGCTTCAG 
TACAGACAGG AGAAAGCCCT GAATAAGTTT GAAGATGCCG AAAATGAAAT CTCACAACTT 
ATATTTCGTC ATAACAATGA GATTACAGCA CTCAAAGAAC GCTTAAGAAA ATCTCAAGAG 
AAAGAACGGG CAACTGAGAA AAGGGTAAAA GATACAGAAA GTGAACTATT TAGGACAAAA 
TTTTCCTTAC AGAAACTGAA AGAGATCTCT GAAGCTAGAC ACCTACCTGA ACGAGATGAT 
TTGGCAAAGA AACTAGTTTC AGCAGAGTTA AAGTTAGATG ACACCGAGAG AAGAATTAAG 
GAGCTATCGA AAAACCTTGA ACTGAGTACT AACAGTTTCC AACGACAGTT GCTTGCTGAA 
AGGAAAAGGG CATATGAGGC TCATGATGAA AATAAAGTTC TTCAAAAGGA GGTACAGCGA 
CTATATCACA AATTAAAGGA AAAGGAGAGA GAACTGGATA TAAAAAATAT ATATTCTAAT 
CGTCTGCCAA AGTCCTCTCC AAATAAAGAG AAAGAACTTG CATTAAGAAA AAATGCTGCA 
TGCCAGAGTG ATTTTGCAGA CCTGTGTACA AAAGGAGTAC AAACCATGGA AGACTTCAAG 
CCAGAAGAAT ATCCTTTAAC TCCAGAAACA ATTATGTGTT ACGAAAACAA ATGGGAAGAA 
CCAGGACATC TTACTTTGGA CTTGCAATCT CAAAAGCAAG ACAGGCATGG AGAAGCAGGG 
ATTCTAAACC CAATTATGGA AAGAGAAGAA AAATTTGTTA CAGATGAAGA ACTCCATGTC 
GTAAAACAGG AGGTTGAAAA GCTGGAGGAT GAATGGGAAA GAGAAGAACT TGATAAAAAG 
CAAAAAGAAA AGGCATCTTT ACTGGAAAGA GAAGAAAAGC CAGAGTGGGA AACTGGAAGG 
TACCAACTAG GAATGTATCC AATTCAGAAT ATGGATAAAT TGCAAGGAGA GGAAGAAGAA 
AGACTGAAGA GAGAAATGCT ACTTGCTAAA CTGAATGAAA TTGACAGAGA ACTCCAAGAT 
TCTCGAAATC TAAAATACCC TGTTTTGCCA TTGTTACCTG ATTTTGAATC AAAACTACAC 
TCCCCAGAGA GAAGCCCCAA AACATACAGG TTCTCTGAAT CCTCAGAGAG ATTATTTAAT 
GGGCATCATT TGCAAGACAT CAGTTTCTCA ACTCCAAAAG GAGAAGGTCA GAATTCAGGA 
AATGTTAGAA GTCCAGCCTC CCCTAATGAG TTCGCATTTG GTAGCTACGT GCCTTCGTTT 
GCAAAAACAT CAGAGAGGTC AAATCCATTT AGTCAAAAAA GTAGTTTTTT GGATTTCCAA 
AGAAACAGTA TGGAAAAACT TAGTAAAGAT GGTGTAGATT TAATTACAAG AAAAGAGAAA 
AAAGCTAATT TGATGGAACA GTTATTTGGT GCCAGTGGTA GCAGCACCAT TTCCTCCAAA 
AGCAGTGACC CAAATTCTGT GGCTTCCAGT AAAGGAGACA TTGACCCTCT AAATTTTCTC 
CCTGGGAATA AAGGCAGCAG AGATCAAGAA CATGATGAAG ATGAAGGCTT TTTCCTCAGT 
GAAGGAAGAA GTTTTAATCC AAATAGGCAC CGATTAAAAC ATGCAGACGA TAAACCAGCA 
GTAAAAGCAG CTGATTCTGT AGAAGATGAA ATTGAAGAAG TAGCACTGAG ATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_859065.2
CDS	613..2706
Translation	MGERAGSPGTDQERKAGKHHYSYLSDFETPQSSGRSSLVSSSPASVRRKNPKRQTSDGQVHHQAPRKPSPKGLPNRKGVRVGFRSQSLNREPLRKDTDLVTKRILSARLLKINELQNEVSELQVKLAELLKENKSLKRLQYRQEKALNKFEDAENEISQLIFRHNNEITALKERLRKSQEKERATEKRVKDTESELFRTKFSLQKLKEISEARHLPERDDLAKKLVSAELKLDDTERRIKELSKNLELSTNSFQRQLLAERKRAYEAHDENKVLQKEVQRLYHKLKEKERELDIKNIYSNRLPKSSPNKEKELALRKNAACQSDFADLCTKGVQTMEDFKPEEYPLTPETIMCYENKWEEPGHLTLDLQSQKQDRHGEAGILNPIMEREEKFVTDEELHVVKQEVEKLEDEWEREELDKKQKEKASLLEREEKPEWETGRYQLGMYPIQNMDKLQGEEEERLKREMLLAKLNEIDRELQDSRNLKYPVLPLLPDFESKLHSPERSPKTYRFSESSERLFNGHHLQDISFSTPKGEGQNSGNVRSPASPNEFAFGSYVPSFAKTSERSNPFSQKSSFLDFQRNSMEKLSKDGVDLITRKEKKANLMEQLFGASGSSTISSKSSDPNSVASSKGDIDPLNFLPGNKGSRDQEHDEDEGFFLSEGRSFNPNRHRLKHADDKPAVKAADSVEDEIEEVALR

Target ORF information:

RefSeq Version	NM_181714.4
Organism	Homo sapiens(human)
Definition	Homo sapiens lebercilin LCA5 (LCA5), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_181714.4

ORF Insert Sequence:

ATGGGGGAAA GAGCAGGAAG TCCAGGTACT GATCAAGAAA GAAAGGCAGG CAAACACCAT 
TATTCTTACT TATCTGATTT TGAAACGCCA CAGTCTTCTG GCCGATCATC GCTGGTCAGT 
TCTTCACCTG CAAGTGTTAG GAGAAAAAAT CCTAAAAGAC AAACTTCAGA TGGCCAAGTA 
CATCACCAAG CCCCTCGGAA ACCAAGCCCT AAGGGTCTAC CAAACAGAAA GGGAGTCCGA 
GTGGGATTTC GCTCCCAGAG CCTCAATAGA GAGCCACTTC GGAAAGATAC TGATCTTGTT 
ACAAAACGGA TTCTGTCTGC AAGACTGCTA AAAATCAATG AGTTGCAGAA TGAAGTATCT 
GAACTCCAGG TCAAGTTAGC TGAGCTGCTA AAAGAAAATA AATCTTTGAA AAGGCTTCAG 
TACAGACAGG AGAAAGCCCT GAATAAGTTT GAAGATGCCG AAAATGAAAT CTCACAACTT 
ATATTTCGTC ATAACAATGA GATTACAGCA CTCAAAGAAC GCTTAAGAAA ATCTCAAGAG 
AAAGAACGGG CAACTGAGAA AAGGGTAAAA GATACAGAAA GTGAACTATT TAGGACAAAA 
TTTTCCTTAC AGAAACTGAA AGAGATCTCT GAAGCTAGAC ACCTACCTGA ACGAGATGAT 
TTGGCAAAGA AACTAGTTTC AGCAGAGTTA AAGTTAGATG ACACCGAGAG AAGAATTAAG 
GAGCTATCGA AAAACCTTGA ACTGAGTACT AACAGTTTCC AACGACAGTT GCTTGCTGAA 
AGGAAAAGGG CATATGAGGC TCATGATGAA AATAAAGTTC TTCAAAAGGA GGTACAGCGA 
CTATATCACA AATTAAAGGA AAAGGAGAGA GAACTGGATA TAAAAAATAT ATATTCTAAT 
CGTCTGCCAA AGTCCTCTCC AAATAAAGAG AAAGAACTTG CATTAAGAAA AAATGCTGCA 
TGCCAGAGTG ATTTTGCAGA CCTGTGTACA AAAGGAGTAC AAACCATGGA AGACTTCAAG 
CCAGAAGAAT ATCCTTTAAC TCCAGAAACA ATTATGTGTT ACGAAAACAA ATGGGAAGAA 
CCAGGACATC TTACTTTGGA CTTGCAATCT CAAAAGCAAG ACAGGCATGG AGAAGCAGGG 
ATTCTAAACC CAATTATGGA AAGAGAAGAA AAATTTGTTA CAGATGAAGA ACTCCATGTC 
GTAAAACAGG AGGTTGAAAA GCTGGAGGAT GAATGGGAAA GAGAAGAACT TGATAAAAAG 
CAAAAAGAAA AGGCATCTTT ACTGGAAAGA GAAGAAAAGC CAGAGTGGGA AACTGGAAGG 
TACCAACTAG GAATGTATCC AATTCAGAAT ATGGATAAAT TGCAAGGAGA GGAAGAAGAA 
AGACTGAAGA GAGAAATGCT ACTTGCTAAA CTGAATGAAA TTGACAGAGA ACTCCAAGAT 
TCTCGAAATC TAAAATACCC TGTTTTGCCA TTGTTACCTG ATTTTGAATC AAAACTACAC 
TCCCCAGAGA GAAGCCCCAA AACATACAGG TTCTCTGAAT CCTCAGAGAG ATTATTTAAT 
GGGCATCATT TGCAAGACAT CAGTTTCTCA ACTCCAAAAG GAGAAGGTCA GAATTCAGGA 
AATGTTAGAA GTCCAGCCTC CCCTAATGAG TTCGCATTTG GTAGCTACGT GCCTTCGTTT 
GCAAAAACAT CAGAGAGGTC AAATCCATTT AGTCAAAAAA GTAGTTTTTT GGATTTCCAA 
AGAAACAGTA TGGAAAAACT TAGTAAAGAT GGTGTAGATT TAATTACAAG AAAAGAGAAA 
AAAGCTAATT TGATGGAACA GTTATTTGGT GCCAGTGGTA GCAGCACCAT TTCCTCCAAA 
AGCAGTGACC CAAATTCTGT GGCTTCCAGT AAAGGAGACA TTGACCCTCT AAATTTTCTC 
CCTGGGAATA AAGGCAGCAG AGATCAAGAA CATGATGAAG ATGAAGGCTT TTTCCTCAGT 
GAAGGAAGAA GTTTTAATCC AAATAGGCAC CGATTAAAAC ATGCAGACGA TAAACCAGCA 
GTAAAAGCAG CTGATTCTGT AGAAGATGAA ATTGAAGAAG TAGCACTGAG ATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

LCA5 ( XM_005248665.3 ) cDNA ORF clone, Homo sapiens(human) -> XP_005248722.1 Homo sapiens Leber congenital amaurosis 5 (LCA5), transcript variant X2, mRNA.

Price & Availability↑

CloneID	OHu16637
Clone ID Related Accession (Same CDS sequence)	XM_005248665.3 , NM_001122769.2 , XM_011535504.1 , XM_005248665.4 , NM_001122769.3 , NM_181714.3 , NM_181714.4
Accession Version	XM_005248665.3	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2094bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2015-03-11
Organism	Homo sapiens(Human)
Product	lebercilin isoform X1
Comment

ATGGGGGAAA GAGCAGGAAG TCCAGGTACT GATCAAGAAA GAAAGGCAGG CAAACACCAT 
TATTCTTACT TATCTGATTT TGAAACGCCA CAGTCTTCTG GCCGATCATC GCTGGTCAGT 
TCTTCACCTG CAAGTGTTAG GAGAAAAAAT CCTAAAAGAC AAACTTCAGA TGGCCAAGTA 
CATCACCAAG CCCCTCGGAA ACCAAGCCCT AAGGGTCTAC CAAACAGAAA GGGAGTCCGA 
GTGGGATTTC GCTCCCAGAG CCTCAATAGA GAGCCACTTC GGAAAGATAC TGATCTTGTT 
ACAAAACGGA TTCTGTCTGC AAGACTGCTA AAAATCAATG AGTTGCAGAA TGAAGTATCT 
GAACTCCAGG TCAAGTTAGC TGAGCTGCTA AAAGAAAATA AATCTTTGAA AAGGCTTCAG 
TACAGACAGG AGAAAGCCCT GAATAAGTTT GAAGATGCCG AAAATGAAAT CTCACAACTT 
ATATTTCGTC ATAACAATGA GATTACAGCA CTCAAAGAAC GCTTAAGAAA ATCTCAAGAG 
AAAGAACGGG CAACTGAGAA AAGGGTAAAA GATACAGAAA GTGAACTATT TAGGACAAAA 
TTTTCCTTAC AGAAACTGAA AGAGATCTCT GAAGCTAGAC ACCTACCTGA ACGAGATGAT 
TTGGCAAAGA AACTAGTTTC AGCAGAGTTA AAGTTAGATG ACACCGAGAG AAGAATTAAG 
GAGCTATCGA AAAACCTTGA ACTGAGTACT AACAGTTTCC AACGACAGTT GCTTGCTGAA 
AGGAAAAGGG CATATGAGGC TCATGATGAA AATAAAGTTC TTCAAAAGGA GGTACAGCGA 
CTATATCACA AATTAAAGGA AAAGGAGAGA GAACTGGATA TAAAAAATAT ATATTCTAAT 
CGTCTGCCAA AGTCCTCTCC AAATAAAGAG AAAGAACTTG CATTAAGAAA AAATGCTGCA 
TGCCAGAGTG ATTTTGCAGA CCTGTGTACA AAAGGAGTAC AAACCATGGA AGACTTCAAG 
CCAGAAGAAT ATCCTTTAAC TCCAGAAACA ATTATGTGTT ACGAAAACAA ATGGGAAGAA 
CCAGGACATC TTACTTTGGA CTTGCAATCT CAAAAGCAAG ACAGGCATGG AGAAGCAGGG 
ATTCTAAACC CAATTATGGA AAGAGAAGAA AAATTTGTTA CAGATGAAGA ACTCCATGTC 
GTAAAACAGG AGGTTGAAAA GCTGGAGGAT GAATGGGAAA GAGAAGAACT TGATAAAAAG 
CAAAAAGAAA AGGCATCTTT ACTGGAAAGA GAAGAAAAGC CAGAGTGGGA AACTGGAAGG 
TACCAACTAG GAATGTATCC AATTCAGAAT ATGGATAAAT TGCAAGGAGA GGAAGAAGAA 
AGACTGAAGA GAGAAATGCT ACTTGCTAAA CTGAATGAAA TTGACAGAGA ACTCCAAGAT 
TCTCGAAATC TAAAATACCC TGTTTTGCCA TTGTTACCTG ATTTTGAATC AAAACTACAC 
TCCCCAGAGA GAAGCCCCAA AACATACAGG TTCTCTGAAT CCTCAGAGAG ATTATTTAAT 
GGGCATCATT TGCAAGACAT CAGTTTCTCA ACTCCAAAAG GAGAAGGTCA GAATTCAGGA 
AATGTTAGAA GTCCAGCCTC CCCTAATGAG TTCGCATTTG GTAGCTACGT GCCTTCGTTT 
GCAAAAACAT CAGAGAGGTC AAATCCATTT AGTCAAAAAA GTAGTTTTTT GGATTTCCAA 
AGAAACAGTA TGGAAAAACT TAGTAAAGAT GGTGTAGATT TAATTACAAG AAAAGAGAAA 
AAAGCTAATT TGATGGAACA GTTATTTGGT GCCAGTGGTA GCAGCACCAT TTCCTCCAAA 
AGCAGTGACC CAAATTCTGT GGCTTCCAGT AAAGGAGACA TTGACCCTCT AAATTTTCTC 
CCTGGGAATA AAGGCAGCAG AGATCAAGAA CATGATGAAG ATGAAGGCTT TTTCCTCAGT 
GAAGGAAGAA GTTTTAATCC AAATAGGCAC CGATTAAAAC ATGCAGACGA TAAACCAGCA 
GTAAAAGCAG CTGATTCTGT AGAAGATGAA ATTGAAGAAG TAGCACTGAG ATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq

XP_005248722.1

Translation

MGERAGSPGTDQERKAGKHHYSYLSDFETPQSSGRSSLVSSSPASVRRKNPKRQTSDGQVHHQAPRKPSPKGLPNRKGVRVGFRSQSLNREPLRKDTDLVTKRILSARLLKINELQNEVSELQVKLAELLKENKSLKRLQYRQEKALNKFEDAENEISQLIFRHNNEITALKERLRKSQEKERATEKRVKDTESELFRTKFSLQKLKEISEARHLPERDDLAKKLVSAELKLDDTERRIKELSKNLELSTNSFQRQLLAERKRAYEAHDENKVLQKEVQRLYHKLKEKERELDIKNIYSNRLPKSSPNKEKELALRKNAACQSDFADLCTKGVQTMEDFKPEEYPLTPETIMCYENKWEEPGHLTLDLQSQKQDRHGEAGILNPIMEREEKFVTDEELHVVKQEVEKLEDEWEREELDKKQKEKASLLEREEKPEWETGRYQLGMYPIQNMDKLQGEEEERLKREMLLAKLNEIDRELQDSRNLKYPVLPLLPDFESKLHSPERSPKTYRFSESSERLFNGHHLQDISFSTPKGEGQNSGNVRSPASPNEFAFGSYVPSFAKTSERSNPFSQKSSFLDFQRNSMEKLSKDGVDLITRKEKKANLMEQLFGASGSSTISSKSSDPNSVASSKGDIDPLNFLPGNKGSRDQEHDEDEGFFLSEGRSFNPNRHRLKHADDKPAVKAADSVEDEIEEVALR

Target ORF information:

RefSeq Version	XM_005248665.3
Organism	Homo sapiens(Human)
Definition	Homo sapiens Leber congenital amaurosis 5 (LCA5), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_005248665.3

ORF Insert Sequence:

ATGGGGGAAA GAGCAGGAAG TCCAGGTACT GATCAAGAAA GAAAGGCAGG CAAACACCAT 
TATTCTTACT TATCTGATTT TGAAACGCCA CAGTCTTCTG GCCGATCATC GCTGGTCAGT 
TCTTCACCTG CAAGTGTTAG GAGAAAAAAT CCTAAAAGAC AAACTTCAGA TGGCCAAGTA 
CATCACCAAG CCCCTCGGAA ACCAAGCCCT AAGGGTCTAC CAAACAGAAA GGGAGTCCGA 
GTGGGATTTC GCTCCCAGAG CCTCAATAGA GAGCCACTTC GGAAAGATAC TGATCTTGTT 
ACAAAACGGA TTCTGTCTGC AAGACTGCTA AAAATCAATG AGTTGCAGAA TGAAGTATCT 
GAACTCCAGG TCAAGTTAGC TGAGCTGCTA AAAGAAAATA AATCTTTGAA AAGGCTTCAG 
TACAGACAGG AGAAAGCCCT GAATAAGTTT GAAGATGCCG AAAATGAAAT CTCACAACTT 
ATATTTCGTC ATAACAATGA GATTACAGCA CTCAAAGAAC GCTTAAGAAA ATCTCAAGAG 
AAAGAACGGG CAACTGAGAA AAGGGTAAAA GATACAGAAA GTGAACTATT TAGGACAAAA 
TTTTCCTTAC AGAAACTGAA AGAGATCTCT GAAGCTAGAC ACCTACCTGA ACGAGATGAT 
TTGGCAAAGA AACTAGTTTC AGCAGAGTTA AAGTTAGATG ACACCGAGAG AAGAATTAAG 
GAGCTATCGA AAAACCTTGA ACTGAGTACT AACAGTTTCC AACGACAGTT GCTTGCTGAA 
AGGAAAAGGG CATATGAGGC TCATGATGAA AATAAAGTTC TTCAAAAGGA GGTACAGCGA 
CTATATCACA AATTAAAGGA AAAGGAGAGA GAACTGGATA TAAAAAATAT ATATTCTAAT 
CGTCTGCCAA AGTCCTCTCC AAATAAAGAG AAAGAACTTG CATTAAGAAA AAATGCTGCA 
TGCCAGAGTG ATTTTGCAGA CCTGTGTACA AAAGGAGTAC AAACCATGGA AGACTTCAAG 
CCAGAAGAAT ATCCTTTAAC TCCAGAAACA ATTATGTGTT ACGAAAACAA ATGGGAAGAA 
CCAGGACATC TTACTTTGGA CTTGCAATCT CAAAAGCAAG ACAGGCATGG AGAAGCAGGG 
ATTCTAAACC CAATTATGGA AAGAGAAGAA AAATTTGTTA CAGATGAAGA ACTCCATGTC 
GTAAAACAGG AGGTTGAAAA GCTGGAGGAT GAATGGGAAA GAGAAGAACT TGATAAAAAG 
CAAAAAGAAA AGGCATCTTT ACTGGAAAGA GAAGAAAAGC CAGAGTGGGA AACTGGAAGG 
TACCAACTAG GAATGTATCC AATTCAGAAT ATGGATAAAT TGCAAGGAGA GGAAGAAGAA 
AGACTGAAGA GAGAAATGCT ACTTGCTAAA CTGAATGAAA TTGACAGAGA ACTCCAAGAT 
TCTCGAAATC TAAAATACCC TGTTTTGCCA TTGTTACCTG ATTTTGAATC AAAACTACAC 
TCCCCAGAGA GAAGCCCCAA AACATACAGG TTCTCTGAAT CCTCAGAGAG ATTATTTAAT 
GGGCATCATT TGCAAGACAT CAGTTTCTCA ACTCCAAAAG GAGAAGGTCA GAATTCAGGA 
AATGTTAGAA GTCCAGCCTC CCCTAATGAG TTCGCATTTG GTAGCTACGT GCCTTCGTTT 
GCAAAAACAT CAGAGAGGTC AAATCCATTT AGTCAAAAAA GTAGTTTTTT GGATTTCCAA 
AGAAACAGTA TGGAAAAACT TAGTAAAGAT GGTGTAGATT TAATTACAAG AAAAGAGAAA 
AAAGCTAATT TGATGGAACA GTTATTTGGT GCCAGTGGTA GCAGCACCAT TTCCTCCAAA 
AGCAGTGACC CAAATTCTGT GGCTTCCAGT AAAGGAGACA TTGACCCTCT AAATTTTCTC 
CCTGGGAATA AAGGCAGCAG AGATCAAGAA CATGATGAAG ATGAAGGCTT TTTCCTCAGT 
GAAGGAAGAA GTTTTAATCC AAATAGGCAC CGATTAAAAC ATGCAGACGA TAAACCAGCA 
GTAAAAGCAG CTGATTCTGT AGAAGATGAA ATTGAAGAAG TAGCACTGAG ATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

LCA5 ( XM_011535504.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_011533806.1 Homo sapiens lebercilin LCA5 (LCA5), transcript variant X1, mRNA.

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CloneID	OHu16637
Clone ID Related Accession (Same CDS sequence)	XM_005248665.3 , NM_001122769.2 , XM_011535504.1 , XM_005248665.4 , NM_001122769.3 , NM_181714.3 , NM_181714.4
Accession Version	XM_011535504.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2094bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	lebercilin isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000006.12) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGGGGAAA GAGCAGGAAG TCCAGGTACT GATCAAGAAA GAAAGGCAGG CAAACACCAT 
TATTCTTACT TATCTGATTT TGAAACGCCA CAGTCTTCTG GCCGATCATC GCTGGTCAGT 
TCTTCACCTG CAAGTGTTAG GAGAAAAAAT CCTAAAAGAC AAACTTCAGA TGGCCAAGTA 
CATCACCAAG CCCCTCGGAA ACCAAGCCCT AAGGGTCTAC CAAACAGAAA GGGAGTCCGA 
GTGGGATTTC GCTCCCAGAG CCTCAATAGA GAGCCACTTC GGAAAGATAC TGATCTTGTT 
ACAAAACGGA TTCTGTCTGC AAGACTGCTA AAAATCAATG AGTTGCAGAA TGAAGTATCT 
GAACTCCAGG TCAAGTTAGC TGAGCTGCTA AAAGAAAATA AATCTTTGAA AAGGCTTCAG 
TACAGACAGG AGAAAGCCCT GAATAAGTTT GAAGATGCCG AAAATGAAAT CTCACAACTT 
ATATTTCGTC ATAACAATGA GATTACAGCA CTCAAAGAAC GCTTAAGAAA ATCTCAAGAG 
AAAGAACGGG CAACTGAGAA AAGGGTAAAA GATACAGAAA GTGAACTATT TAGGACAAAA 
TTTTCCTTAC AGAAACTGAA AGAGATCTCT GAAGCTAGAC ACCTACCTGA ACGAGATGAT 
TTGGCAAAGA AACTAGTTTC AGCAGAGTTA AAGTTAGATG ACACCGAGAG AAGAATTAAG 
GAGCTATCGA AAAACCTTGA ACTGAGTACT AACAGTTTCC AACGACAGTT GCTTGCTGAA 
AGGAAAAGGG CATATGAGGC TCATGATGAA AATAAAGTTC TTCAAAAGGA GGTACAGCGA 
CTATATCACA AATTAAAGGA AAAGGAGAGA GAACTGGATA TAAAAAATAT ATATTCTAAT 
CGTCTGCCAA AGTCCTCTCC AAATAAAGAG AAAGAACTTG CATTAAGAAA AAATGCTGCA 
TGCCAGAGTG ATTTTGCAGA CCTGTGTACA AAAGGAGTAC AAACCATGGA AGACTTCAAG 
CCAGAAGAAT ATCCTTTAAC TCCAGAAACA ATTATGTGTT ACGAAAACAA ATGGGAAGAA 
CCAGGACATC TTACTTTGGA CTTGCAATCT CAAAAGCAAG ACAGGCATGG AGAAGCAGGG 
ATTCTAAACC CAATTATGGA AAGAGAAGAA AAATTTGTTA CAGATGAAGA ACTCCATGTC 
GTAAAACAGG AGGTTGAAAA GCTGGAGGAT GAATGGGAAA GAGAAGAACT TGATAAAAAG 
CAAAAAGAAA AGGCATCTTT ACTGGAAAGA GAAGAAAAGC CAGAGTGGGA AACTGGAAGG 
TACCAACTAG GAATGTATCC AATTCAGAAT ATGGATAAAT TGCAAGGAGA GGAAGAAGAA 
AGACTGAAGA GAGAAATGCT ACTTGCTAAA CTGAATGAAA TTGACAGAGA ACTCCAAGAT 
TCTCGAAATC TAAAATACCC TGTTTTGCCA TTGTTACCTG ATTTTGAATC AAAACTACAC 
TCCCCAGAGA GAAGCCCCAA AACATACAGG TTCTCTGAAT CCTCAGAGAG ATTATTTAAT 
GGGCATCATT TGCAAGACAT CAGTTTCTCA ACTCCAAAAG GAGAAGGTCA GAATTCAGGA 
AATGTTAGAA GTCCAGCCTC CCCTAATGAG TTCGCATTTG GTAGCTACGT GCCTTCGTTT 
GCAAAAACAT CAGAGAGGTC AAATCCATTT AGTCAAAAAA GTAGTTTTTT GGATTTCCAA 
AGAAACAGTA TGGAAAAACT TAGTAAAGAT GGTGTAGATT TAATTACAAG AAAAGAGAAA 
AAAGCTAATT TGATGGAACA GTTATTTGGT GCCAGTGGTA GCAGCACCAT TTCCTCCAAA 
AGCAGTGACC CAAATTCTGT GGCTTCCAGT AAAGGAGACA TTGACCCTCT AAATTTTCTC 
CCTGGGAATA AAGGCAGCAG AGATCAAGAA CATGATGAAG ATGAAGGCTT TTTCCTCAGT 
GAAGGAAGAA GTTTTAATCC AAATAGGCAC CGATTAAAAC ATGCAGACGA TAAACCAGCA 
GTAAAAGCAG CTGATTCTGT AGAAGATGAA ATTGAAGAAG TAGCACTGAG ATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_011533806.1
CDS	525..2618
Translation	MGERAGSPGTDQERKAGKHHYSYLSDFETPQSSGRSSLVSSSPASVRRKNPKRQTSDGQVHHQAPRKPSPKGLPNRKGVRVGFRSQSLNREPLRKDTDLVTKRILSARLLKINELQNEVSELQVKLAELLKENKSLKRLQYRQEKALNKFEDAENEISQLIFRHNNEITALKERLRKSQEKERATEKRVKDTESELFRTKFSLQKLKEISEARHLPERDDLAKKLVSAELKLDDTERRIKELSKNLELSTNSFQRQLLAERKRAYEAHDENKVLQKEVQRLYHKLKEKERELDIKNIYSNRLPKSSPNKEKELALRKNAACQSDFADLCTKGVQTMEDFKPEEYPLTPETIMCYENKWEEPGHLTLDLQSQKQDRHGEAGILNPIMEREEKFVTDEELHVVKQEVEKLEDEWEREELDKKQKEKASLLEREEKPEWETGRYQLGMYPIQNMDKLQGEEEERLKREMLLAKLNEIDRELQDSRNLKYPVLPLLPDFESKLHSPERSPKTYRFSESSERLFNGHHLQDISFSTPKGEGQNSGNVRSPASPNEFAFGSYVPSFAKTSERSNPFSQKSSFLDFQRNSMEKLSKDGVDLITRKEKKANLMEQLFGASGSSTISSKSSDPNSVASSKGDIDPLNFLPGNKGSRDQEHDEDEGFFLSEGRSFNPNRHRLKHADDKPAVKAADSVEDEIEEVALR

Target ORF information:

RefSeq Version	XM_011535504.1
Organism	Homo sapiens(human)
Definition	Homo sapiens lebercilin LCA5 (LCA5), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011535504.1

ORF Insert Sequence:

ATGGGGGAAA GAGCAGGAAG TCCAGGTACT GATCAAGAAA GAAAGGCAGG CAAACACCAT 
TATTCTTACT TATCTGATTT TGAAACGCCA CAGTCTTCTG GCCGATCATC GCTGGTCAGT 
TCTTCACCTG CAAGTGTTAG GAGAAAAAAT CCTAAAAGAC AAACTTCAGA TGGCCAAGTA 
CATCACCAAG CCCCTCGGAA ACCAAGCCCT AAGGGTCTAC CAAACAGAAA GGGAGTCCGA 
GTGGGATTTC GCTCCCAGAG CCTCAATAGA GAGCCACTTC GGAAAGATAC TGATCTTGTT 
ACAAAACGGA TTCTGTCTGC AAGACTGCTA AAAATCAATG AGTTGCAGAA TGAAGTATCT 
GAACTCCAGG TCAAGTTAGC TGAGCTGCTA AAAGAAAATA AATCTTTGAA AAGGCTTCAG 
TACAGACAGG AGAAAGCCCT GAATAAGTTT GAAGATGCCG AAAATGAAAT CTCACAACTT 
ATATTTCGTC ATAACAATGA GATTACAGCA CTCAAAGAAC GCTTAAGAAA ATCTCAAGAG 
AAAGAACGGG CAACTGAGAA AAGGGTAAAA GATACAGAAA GTGAACTATT TAGGACAAAA 
TTTTCCTTAC AGAAACTGAA AGAGATCTCT GAAGCTAGAC ACCTACCTGA ACGAGATGAT 
TTGGCAAAGA AACTAGTTTC AGCAGAGTTA AAGTTAGATG ACACCGAGAG AAGAATTAAG 
GAGCTATCGA AAAACCTTGA ACTGAGTACT AACAGTTTCC AACGACAGTT GCTTGCTGAA 
AGGAAAAGGG CATATGAGGC TCATGATGAA AATAAAGTTC TTCAAAAGGA GGTACAGCGA 
CTATATCACA AATTAAAGGA AAAGGAGAGA GAACTGGATA TAAAAAATAT ATATTCTAAT 
CGTCTGCCAA AGTCCTCTCC AAATAAAGAG AAAGAACTTG CATTAAGAAA AAATGCTGCA 
TGCCAGAGTG ATTTTGCAGA CCTGTGTACA AAAGGAGTAC AAACCATGGA AGACTTCAAG 
CCAGAAGAAT ATCCTTTAAC TCCAGAAACA ATTATGTGTT ACGAAAACAA ATGGGAAGAA 
CCAGGACATC TTACTTTGGA CTTGCAATCT CAAAAGCAAG ACAGGCATGG AGAAGCAGGG 
ATTCTAAACC CAATTATGGA AAGAGAAGAA AAATTTGTTA CAGATGAAGA ACTCCATGTC 
GTAAAACAGG AGGTTGAAAA GCTGGAGGAT GAATGGGAAA GAGAAGAACT TGATAAAAAG 
CAAAAAGAAA AGGCATCTTT ACTGGAAAGA GAAGAAAAGC CAGAGTGGGA AACTGGAAGG 
TACCAACTAG GAATGTATCC AATTCAGAAT ATGGATAAAT TGCAAGGAGA GGAAGAAGAA 
AGACTGAAGA GAGAAATGCT ACTTGCTAAA CTGAATGAAA TTGACAGAGA ACTCCAAGAT 
TCTCGAAATC TAAAATACCC TGTTTTGCCA TTGTTACCTG ATTTTGAATC AAAACTACAC 
TCCCCAGAGA GAAGCCCCAA AACATACAGG TTCTCTGAAT CCTCAGAGAG ATTATTTAAT 
GGGCATCATT TGCAAGACAT CAGTTTCTCA ACTCCAAAAG GAGAAGGTCA GAATTCAGGA 
AATGTTAGAA GTCCAGCCTC CCCTAATGAG TTCGCATTTG GTAGCTACGT GCCTTCGTTT 
GCAAAAACAT CAGAGAGGTC AAATCCATTT AGTCAAAAAA GTAGTTTTTT GGATTTCCAA 
AGAAACAGTA TGGAAAAACT TAGTAAAGAT GGTGTAGATT TAATTACAAG AAAAGAGAAA 
AAAGCTAATT TGATGGAACA GTTATTTGGT GCCAGTGGTA GCAGCACCAT TTCCTCCAAA 
AGCAGTGACC CAAATTCTGT GGCTTCCAGT AAAGGAGACA TTGACCCTCT AAATTTTCTC 
CCTGGGAATA AAGGCAGCAG AGATCAAGAA CATGATGAAG ATGAAGGCTT TTTCCTCAGT 
GAAGGAAGAA GTTTTAATCC AAATAGGCAC CGATTAAAAC ATGCAGACGA TAAACCAGCA 
GTAAAAGCAG CTGATTCTGT AGAAGATGAA ATTGAAGAAG TAGCACTGAG ATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

LCA5 ( XM_005248665.4 ) cDNA ORF clone, Homo sapiens(human) -> XP_005248722.1 Homo sapiens lebercilin LCA5 (LCA5), transcript variant X2, mRNA.

Price & Availability↑

CloneID	OHu16637
Clone ID Related Accession (Same CDS sequence)	XM_005248665.3 , NM_001122769.2 , XM_011535504.1 , XM_005248665.4 , NM_001122769.3 , NM_181714.3 , NM_181714.4
Accession Version	XM_005248665.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2094bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	lebercilin isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000006.12) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 6, 2016 this sequence version replaced XM_005248665.3. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGGGGAAA GAGCAGGAAG TCCAGGTACT GATCAAGAAA GAAAGGCAGG CAAACACCAT 
TATTCTTACT TATCTGATTT TGAAACGCCA CAGTCTTCTG GCCGATCATC GCTGGTCAGT 
TCTTCACCTG CAAGTGTTAG GAGAAAAAAT CCTAAAAGAC AAACTTCAGA TGGCCAAGTA 
CATCACCAAG CCCCTCGGAA ACCAAGCCCT AAGGGTCTAC CAAACAGAAA GGGAGTCCGA 
GTGGGATTTC GCTCCCAGAG CCTCAATAGA GAGCCACTTC GGAAAGATAC TGATCTTGTT 
ACAAAACGGA TTCTGTCTGC AAGACTGCTA AAAATCAATG AGTTGCAGAA TGAAGTATCT 
GAACTCCAGG TCAAGTTAGC TGAGCTGCTA AAAGAAAATA AATCTTTGAA AAGGCTTCAG 
TACAGACAGG AGAAAGCCCT GAATAAGTTT GAAGATGCCG AAAATGAAAT CTCACAACTT 
ATATTTCGTC ATAACAATGA GATTACAGCA CTCAAAGAAC GCTTAAGAAA ATCTCAAGAG 
AAAGAACGGG CAACTGAGAA AAGGGTAAAA GATACAGAAA GTGAACTATT TAGGACAAAA 
TTTTCCTTAC AGAAACTGAA AGAGATCTCT GAAGCTAGAC ACCTACCTGA ACGAGATGAT 
TTGGCAAAGA AACTAGTTTC AGCAGAGTTA AAGTTAGATG ACACCGAGAG AAGAATTAAG 
GAGCTATCGA AAAACCTTGA ACTGAGTACT AACAGTTTCC AACGACAGTT GCTTGCTGAA 
AGGAAAAGGG CATATGAGGC TCATGATGAA AATAAAGTTC TTCAAAAGGA GGTACAGCGA 
CTATATCACA AATTAAAGGA AAAGGAGAGA GAACTGGATA TAAAAAATAT ATATTCTAAT 
CGTCTGCCAA AGTCCTCTCC AAATAAAGAG AAAGAACTTG CATTAAGAAA AAATGCTGCA 
TGCCAGAGTG ATTTTGCAGA CCTGTGTACA AAAGGAGTAC AAACCATGGA AGACTTCAAG 
CCAGAAGAAT ATCCTTTAAC TCCAGAAACA ATTATGTGTT ACGAAAACAA ATGGGAAGAA 
CCAGGACATC TTACTTTGGA CTTGCAATCT CAAAAGCAAG ACAGGCATGG AGAAGCAGGG 
ATTCTAAACC CAATTATGGA AAGAGAAGAA AAATTTGTTA CAGATGAAGA ACTCCATGTC 
GTAAAACAGG AGGTTGAAAA GCTGGAGGAT GAATGGGAAA GAGAAGAACT TGATAAAAAG 
CAAAAAGAAA AGGCATCTTT ACTGGAAAGA GAAGAAAAGC CAGAGTGGGA AACTGGAAGG 
TACCAACTAG GAATGTATCC AATTCAGAAT ATGGATAAAT TGCAAGGAGA GGAAGAAGAA 
AGACTGAAGA GAGAAATGCT ACTTGCTAAA CTGAATGAAA TTGACAGAGA ACTCCAAGAT 
TCTCGAAATC TAAAATACCC TGTTTTGCCA TTGTTACCTG ATTTTGAATC AAAACTACAC 
TCCCCAGAGA GAAGCCCCAA AACATACAGG TTCTCTGAAT CCTCAGAGAG ATTATTTAAT 
GGGCATCATT TGCAAGACAT CAGTTTCTCA ACTCCAAAAG GAGAAGGTCA GAATTCAGGA 
AATGTTAGAA GTCCAGCCTC CCCTAATGAG TTCGCATTTG GTAGCTACGT GCCTTCGTTT 
GCAAAAACAT CAGAGAGGTC AAATCCATTT AGTCAAAAAA GTAGTTTTTT GGATTTCCAA 
AGAAACAGTA TGGAAAAACT TAGTAAAGAT GGTGTAGATT TAATTACAAG AAAAGAGAAA 
AAAGCTAATT TGATGGAACA GTTATTTGGT GCCAGTGGTA GCAGCACCAT TTCCTCCAAA 
AGCAGTGACC CAAATTCTGT GGCTTCCAGT AAAGGAGACA TTGACCCTCT AAATTTTCTC 
CCTGGGAATA AAGGCAGCAG AGATCAAGAA CATGATGAAG ATGAAGGCTT TTTCCTCAGT 
GAAGGAAGAA GTTTTAATCC AAATAGGCAC CGATTAAAAC ATGCAGACGA TAAACCAGCA 
GTAAAAGCAG CTGATTCTGT AGAAGATGAA ATTGAAGAAG TAGCACTGAG ATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_005248722.1
CDS	472..2565
Translation	MGERAGSPGTDQERKAGKHHYSYLSDFETPQSSGRSSLVSSSPASVRRKNPKRQTSDGQVHHQAPRKPSPKGLPNRKGVRVGFRSQSLNREPLRKDTDLVTKRILSARLLKINELQNEVSELQVKLAELLKENKSLKRLQYRQEKALNKFEDAENEISQLIFRHNNEITALKERLRKSQEKERATEKRVKDTESELFRTKFSLQKLKEISEARHLPERDDLAKKLVSAELKLDDTERRIKELSKNLELSTNSFQRQLLAERKRAYEAHDENKVLQKEVQRLYHKLKEKERELDIKNIYSNRLPKSSPNKEKELALRKNAACQSDFADLCTKGVQTMEDFKPEEYPLTPETIMCYENKWEEPGHLTLDLQSQKQDRHGEAGILNPIMEREEKFVTDEELHVVKQEVEKLEDEWEREELDKKQKEKASLLEREEKPEWETGRYQLGMYPIQNMDKLQGEEEERLKREMLLAKLNEIDRELQDSRNLKYPVLPLLPDFESKLHSPERSPKTYRFSESSERLFNGHHLQDISFSTPKGEGQNSGNVRSPASPNEFAFGSYVPSFAKTSERSNPFSQKSSFLDFQRNSMEKLSKDGVDLITRKEKKANLMEQLFGASGSSTISSKSSDPNSVASSKGDIDPLNFLPGNKGSRDQEHDEDEGFFLSEGRSFNPNRHRLKHADDKPAVKAADSVEDEIEEVALR

Target ORF information:

RefSeq Version	XM_005248665.4
Organism	Homo sapiens(human)
Definition	Homo sapiens lebercilin LCA5 (LCA5), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_005248665.4

ORF Insert Sequence:

ATGGGGGAAA GAGCAGGAAG TCCAGGTACT GATCAAGAAA GAAAGGCAGG CAAACACCAT 
TATTCTTACT TATCTGATTT TGAAACGCCA CAGTCTTCTG GCCGATCATC GCTGGTCAGT 
TCTTCACCTG CAAGTGTTAG GAGAAAAAAT CCTAAAAGAC AAACTTCAGA TGGCCAAGTA 
CATCACCAAG CCCCTCGGAA ACCAAGCCCT AAGGGTCTAC CAAACAGAAA GGGAGTCCGA 
GTGGGATTTC GCTCCCAGAG CCTCAATAGA GAGCCACTTC GGAAAGATAC TGATCTTGTT 
ACAAAACGGA TTCTGTCTGC AAGACTGCTA AAAATCAATG AGTTGCAGAA TGAAGTATCT 
GAACTCCAGG TCAAGTTAGC TGAGCTGCTA AAAGAAAATA AATCTTTGAA AAGGCTTCAG 
TACAGACAGG AGAAAGCCCT GAATAAGTTT GAAGATGCCG AAAATGAAAT CTCACAACTT 
ATATTTCGTC ATAACAATGA GATTACAGCA CTCAAAGAAC GCTTAAGAAA ATCTCAAGAG 
AAAGAACGGG CAACTGAGAA AAGGGTAAAA GATACAGAAA GTGAACTATT TAGGACAAAA 
TTTTCCTTAC AGAAACTGAA AGAGATCTCT GAAGCTAGAC ACCTACCTGA ACGAGATGAT 
TTGGCAAAGA AACTAGTTTC AGCAGAGTTA AAGTTAGATG ACACCGAGAG AAGAATTAAG 
GAGCTATCGA AAAACCTTGA ACTGAGTACT AACAGTTTCC AACGACAGTT GCTTGCTGAA 
AGGAAAAGGG CATATGAGGC TCATGATGAA AATAAAGTTC TTCAAAAGGA GGTACAGCGA 
CTATATCACA AATTAAAGGA AAAGGAGAGA GAACTGGATA TAAAAAATAT ATATTCTAAT 
CGTCTGCCAA AGTCCTCTCC AAATAAAGAG AAAGAACTTG CATTAAGAAA AAATGCTGCA 
TGCCAGAGTG ATTTTGCAGA CCTGTGTACA AAAGGAGTAC AAACCATGGA AGACTTCAAG 
CCAGAAGAAT ATCCTTTAAC TCCAGAAACA ATTATGTGTT ACGAAAACAA ATGGGAAGAA 
CCAGGACATC TTACTTTGGA CTTGCAATCT CAAAAGCAAG ACAGGCATGG AGAAGCAGGG 
ATTCTAAACC CAATTATGGA AAGAGAAGAA AAATTTGTTA CAGATGAAGA ACTCCATGTC 
GTAAAACAGG AGGTTGAAAA GCTGGAGGAT GAATGGGAAA GAGAAGAACT TGATAAAAAG 
CAAAAAGAAA AGGCATCTTT ACTGGAAAGA GAAGAAAAGC CAGAGTGGGA AACTGGAAGG 
TACCAACTAG GAATGTATCC AATTCAGAAT ATGGATAAAT TGCAAGGAGA GGAAGAAGAA 
AGACTGAAGA GAGAAATGCT ACTTGCTAAA CTGAATGAAA TTGACAGAGA ACTCCAAGAT 
TCTCGAAATC TAAAATACCC TGTTTTGCCA TTGTTACCTG ATTTTGAATC AAAACTACAC 
TCCCCAGAGA GAAGCCCCAA AACATACAGG TTCTCTGAAT CCTCAGAGAG ATTATTTAAT 
GGGCATCATT TGCAAGACAT CAGTTTCTCA ACTCCAAAAG GAGAAGGTCA GAATTCAGGA 
AATGTTAGAA GTCCAGCCTC CCCTAATGAG TTCGCATTTG GTAGCTACGT GCCTTCGTTT 
GCAAAAACAT CAGAGAGGTC AAATCCATTT AGTCAAAAAA GTAGTTTTTT GGATTTCCAA 
AGAAACAGTA TGGAAAAACT TAGTAAAGAT GGTGTAGATT TAATTACAAG AAAAGAGAAA 
AAAGCTAATT TGATGGAACA GTTATTTGGT GCCAGTGGTA GCAGCACCAT TTCCTCCAAA 
AGCAGTGACC CAAATTCTGT GGCTTCCAGT AAAGGAGACA TTGACCCTCT AAATTTTCTC 
CCTGGGAATA AAGGCAGCAG AGATCAAGAA CATGATGAAG ATGAAGGCTT TTTCCTCAGT 
GAAGGAAGAA GTTTTAATCC AAATAGGCAC CGATTAAAAC ATGCAGACGA TAAACCAGCA 
GTAAAAGCAG CTGATTCTGT AGAAGATGAA ATTGAAGAAG TAGCACTGAG ATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Architecture of the human interactome defines protein communities and disease networks.
Nature545(7655)505-509(2017 05)
Huttlin EL,Bruckner RJ,Paulo JA,Cannon JR,Ting L,Baltier K,Colby G,Gebreab F,Gygi MP,Parzen H,Szpyt J,Tam S,Zarraga G,Pontano-Vaites L,Swarup S,White AE,Schweppe DK,Rad R,Erickson BK,Obar RA,Guruharsha KG,Li K,Artavanis-Tsakonas S,Gygi SP,Harper JW

An organelle-specific protein landscape identifies novel diseases and molecular mechanisms.
Nature communications711491(2016 May)
Boldt K,van Reeuwijk J,Lu Q,Koutroumpas K,Nguyen TM,Texier Y,van Beersum SE,Horn N,Willer JR,Mans DA,Dougherty G,Lamers IJ,Coene KL,Arts HH,Betts MJ,Beyer T,Bolat E,Gloeckner CJ,Haidari K,Hetterschijt L,Iaconis D,Jenkins D,Klose F,Knapp B,Latour B,Letteboer SJ,Marcelis CL,Mitic D,Morleo M,Oud MM,Riemersma M,Rix S,Terhal PA,Toedt G,van Dam TJ,de Vrieze E,Wissinger Y,Wu KM,Apic G,Beales PL,Blacque OE,Gibson TJ,Huynen MA,Katsanis N,Kremer H,Omran H,van Wijk E,Wolfrum U,Kepes F,Davis EE,Franco B,Giles RH,Ueffing M,Russell RB,Roepman R,

Next-generation Sequencing Extends the Phenotypic Spectrum for LCA5 Mutations: Novel LCA5 Mutations in Cone Dystrophy.
Scientific reports624357(2016 Apr)
Chen X,Sheng X,Sun X,Zhang Y,Jiang C,Li H,Ding S,Liu Y,Liu W,Li Z,Zhao C

A Dynamic Protein Interaction Landscape of the Human Centrosome-Cilium Interface.
Cell163(6)1484-99(2015 Dec)
Gupta GD,Coyaud ?,Gon?alves J,Mojarad BA,Liu Y,Wu Q,Gheiratmand L,Comartin D,Tkach JM,Cheung SW,Bashkurov M,Hasegan M,Knight JD,Lin ZY,Schueler M,Hildebrandt F,Moffat J,Gingras AC,Raught B,Pelletier L

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LCA5 cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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