LIX1 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	LIX1
Entrez Gene ID	167410
Full Name	limb and CNS expressed 1
Synonyms	C5orf11,Lft
General protein information	Preferred Names limb and CNS expressed 1 Names protein limb expression 1 homolog Lix1 homolog Lowfat homolog limb expression 1
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 5 Map Location: 5q15
Disorder MIM:	610466

mRNA and Protein(s)

mRNA	Protein	Name
NM_153234.5	NP_694966.3	protein limb expression 1 homolog
NM_153234.4	NP_694966.3	protein limb expression 1 homolog

Pathways from BioSystems

Homologies

Danio rerio (zebrafish)	lix1	XP_686266.2
	LIX1	XP_001095680.1
Mus musculus (house mouse)	Lix1	NP_079957.2
Gallus gallus (chicken)	LIX1	NP_989678.1
Rattus norvegicus (Norway rat)	Lix1	NP_001099684.1
Pan troglodytes (chimpanzee)	LIX1	XP_526965.2
Bos taurus (cattle)	LIX1	NP_001071471.1
Homo sapiens (human)	LIX1	NP_694966.3
Canis lupus familiaris (dog)	LIX1	XP_546011.2
Xenopus tropicalis (tropical clawed frog)	lix1	XP_002933479.1

Gene Ontology
Bibliography

Related articles in PubMed

Screening of the LIX1 gene in Japanese and Malaysian patients with SMA and/or SMA-like disorder.
Sasongko TH, Gunadi, Yusoff S, Atif AB, Fatemeh H, Rani A, Marini M, Ab Aziz CB, Zabidi-Hussin ZA, Nishio H, Zilfalil BA
Brain & development32(5)385-9(2010 May)

Sequential use of transcriptional profiling, expression quantitative trait mapping, and gene association implicates MMP20 in human kidney aging.
Wheeler HE, Metter EJ, Tanaka T, Absher D, Higgins J, Zahn JM, Wilhelmy J, Davis RW, Singleton A, Myers RM, Ferrucci L, Kim SK
PLoS genetics5(10)e1000685(2009 Oct)

Drosophila lowfat, a novel modulator of Fat signaling.
Mao Y, Kucuk B, Irvine KD
Development (Cambridge, England)136(19)3223-33(2009 Oct)

Candidate screening of the bovine and feline spinal muscular atrophy genes reveals no evidence for involvement in human motor neuron disorders.
Parkinson NJ, Baumer D, Rose-Morris A, Talbot K
Neuromuscular disorders : NMD18(5)394-7(2008 May)

Murine Lix1, a novel marker for substantia nigra, cortical layer 5, and hindbrain structures.
Moeller C, Yaylaoglu MB, Alvarez-Bolado G, Thaller C, Eichele G
Brain research. Gene expression patterns1(3-4)199-203(2002 Oct)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Observational study of gene-disease association. (HuGE Navigator)
Title: Screening of the LIX1 gene in Japanese and Malaysian patients with SMA and/or SMA-like disorder.

Observational study of gene-disease association. (HuGE Navigator)
Title: Sequential use of transcriptional profiling, expression quantitative trait mapping, and gene association implicates MMP20 in human kidney aging.

Data show that mutations in LIX1 do not contribute significantly to the cause of motor neuron diseases in the human population.
Title: Candidate screening of the bovine and feline spinal muscular atrophy genes reveals no evidence for involvement in human motor neuron disorders.

The following LIX1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the LIX1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu06967	NM_153234.5 Latest version!	Homo sapiens limb and CNS expressed 1 (LIX1), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$154.50-$216.30 $309.00
View Old Accession Versions >>
OHu06967	NM_153234.4	Homo sapiens limb and CNS expressed 1 (LIX1), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$154.50-$216.30 $309.00
Hide Old Accession Versions >>

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

LIX1 ( NM_153234.5 ) cDNA ORF clone, Homo sapiens(human) -> NP_694966.3 Homo sapiens limb and CNS expressed 1 (LIX1), mRNA.

Price & Availability↑

CloneID	OHu06967
Clone ID Related Accession (Same CDS sequence)	NM_153234.5 , NM_153234.4
Accession Version	NM_153234.5 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 849bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-30
Organism	Homo sapiens(human)
Product	protein limb expression 1 homolog
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AK098400.1, BC036467.2 and AC008865.3. On Nov 22, 2018 this sequence version replaced NM_153234.4. ##Evidence-Data-START## Transcript exon combination :: BC036467.2, SRR1803611.193891.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2157437 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000274382.9/ ENSP00000274382.4 RefSeq Select criteria :: based on single protein-coding transcript ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGGACAGAA CCTTGGAATC TCTGAGACAC ATCATTGCCC AAGTCTTGCC TCACAGAGAT 
CCGGCTCTAG TCTTCAAAGA CTTGAACGTT GTGTCAATGT TACAGGAATT TTGGGAAAGC 
AAGCAGCAGC AGAAGGCTGC ATTCCCAAGT GAAGGTGTGG TGGTCTATGA GTCACTGCCA 
GCTCCTGGGC CTCCCTTTGT GAGTTACGTG ACCCTCCCAG GGGGAAGCTG TTTTGGCAAC 
TTTCAGTGCT GCTTAAGTAG AGCCGAGGCC AGGCGGGATG CAGCTAAAGT GGCCCTGATC 
AACTCCCTCT TCAATGAGCT GCCCTCTCGC AGGATCACCA AGGAATTCAT TATGGAAAGT 
GTTCAGGAAG CAGTAGCCTC CACCAGCGGC ACCTTAGATG ATGCAGATGA CCCCAGCACC 
AGTGTTGGGG CCTATCACTA CATGCTGGAG TCAAACATGG GGAAGACTAT GCTGGAGTTT 
CAGGAGCTGA TGACCATTTT CCAACTATTG CACTGGAATG GAAGCCTAAA AGCCCTTCGT 
GAAACAAAGT GTTCCCGACA GGAAGTCATC TCCTACTATT CTCAGTATTC TCTAGATGAA 
AAGATGCGCA GCCACATGGC CCTGGACTGG ATCATGAAGG AGCGGGACTC ACCAGGAATT 
GTCTCTCAAG AGCTACGAAT GGCCCTGAGG CAGTTGGAGG AAGCCAGGAA AGCAGGACAA 
GAACTACGGT TTTACAAAGA AAAGAAAGAA ATATTGAGCT TAGCCCTGAC TCAGATCTGC 
AGTGACCCTG ACACTTCCTC ACCCAGTGAT GATCAGCTGA GCCTTACGGC CCTGTGTGGC 
TATCACTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_694966.3
CDS	36..884
Translation	MDRTLESLRHIIAQVLPHRDPALVFKDLNVVSMLQEFWESKQQQKAAFPSEGVVVYESLPAPGPPFVSYVTLPGGSCFGNFQCCLSRAEARRDAAKVALINSLFNELPSRRITKEFIMESVQEAVASTSGTLDDADDPSTSVGAYHYMLESNMGKTMLEFQELMTIFQLLHWNGSLKALRETKCSRQEVISYYSQYSLDEKMRSHMALDWIMKERDSPGIVSQELRMALRQLEEARKAGQELRFYKEKKEILSLALTQICSDPDTSSPSDDQLSLTALCGYH

Target ORF information:

RefSeq Version	NM_153234.5
Organism	Homo sapiens(human)
Definition	Homo sapiens limb and CNS expressed 1 (LIX1), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_153234.5

ORF Insert Sequence:

ATGGACAGAA CCTTGGAATC TCTGAGACAC ATCATTGCCC AAGTCTTGCC TCACAGAGAT 
CCGGCTCTAG TCTTCAAAGA CTTGAACGTT GTGTCAATGT TACAGGAATT TTGGGAAAGC 
AAGCAGCAGC AGAAGGCTGC ATTCCCAAGT GAAGGTGTGG TGGTCTATGA GTCACTGCCA 
GCTCCTGGGC CTCCCTTTGT GAGTTACGTG ACCCTCCCAG GGGGAAGCTG TTTTGGCAAC 
TTTCAGTGCT GCTTAAGTAG AGCCGAGGCC AGGCGGGATG CAGCTAAAGT GGCCCTGATC 
AACTCCCTCT TCAATGAGCT GCCCTCTCGC AGGATCACCA AGGAATTCAT TATGGAAAGT 
GTTCAGGAAG CAGTAGCCTC CACCAGCGGC ACCTTAGATG ATGCAGATGA CCCCAGCACC 
AGTGTTGGGG CCTATCACTA CATGCTGGAG TCAAACATGG GGAAGACTAT GCTGGAGTTT 
CAGGAGCTGA TGACCATTTT CCAACTATTG CACTGGAATG GAAGCCTAAA AGCCCTTCGT 
GAAACAAAGT GTTCCCGACA GGAAGTCATC TCCTACTATT CTCAGTATTC TCTAGATGAA 
AAGATGCGCA GCCACATGGC CCTGGACTGG ATCATGAAGG AGCGGGACTC ACCAGGAATT 
GTCTCTCAAG AGCTACGAAT GGCCCTGAGG CAGTTGGAGG AAGCCAGGAA AGCAGGACAA 
GAACTACGGT TTTACAAAGA AAAGAAAGAA ATATTGAGCT TAGCCCTGAC TCAGATCTGC 
AGTGACCCTG ACACTTCCTC ACCCAGTGAT GATCAGCTGA GCCTTACGGC CCTGTGTGGC 
TATCACTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

LIX1 ( NM_153234.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_694966.3 Homo sapiens limb and CNS expressed 1 (LIX1), mRNA.

Price & Availability↑

CloneID	OHu06967
Clone ID Related Accession (Same CDS sequence)	NM_153234.5 , NM_153234.4
Accession Version	NM_153234.4	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 849bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-10-01
Organism	Homo sapiens(human)
Product	protein limb expression 1 homolog
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AK098400.1 and BC036467.2. On Feb 8, 2008 this sequence version replaced NM_153234.3. ##Evidence-Data-START## Transcript exon combination :: BC036467.2, SRR1803612.188559.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2157437 [ECO:0000348] ##Evidence-Data-END##

ATGGACAGAA CCTTGGAATC TCTGAGACAC ATCATTGCCC AAGTCTTGCC TCACAGAGAT 
CCGGCTCTAG TCTTCAAAGA CTTGAACGTT GTGTCAATGT TACAGGAATT TTGGGAAAGC 
AAGCAGCAGC AGAAGGCTGC ATTCCCAAGT GAAGGTGTGG TGGTCTATGA GTCACTGCCA 
GCTCCTGGGC CTCCCTTTGT GAGTTACGTG ACCCTCCCAG GGGGAAGCTG TTTTGGCAAC 
TTTCAGTGCT GCTTAAGTAG AGCCGAGGCC AGGCGGGATG CAGCTAAAGT GGCCCTGATC 
AACTCCCTCT TCAATGAGCT GCCCTCTCGC AGGATCACCA AGGAATTCAT TATGGAAAGT 
GTTCAGGAAG CAGTAGCCTC CACCAGCGGC ACCTTAGATG ATGCAGATGA CCCCAGCACC 
AGTGTTGGGG CCTATCACTA CATGCTGGAG TCAAACATGG GGAAGACTAT GCTGGAGTTT 
CAGGAGCTGA TGACCATTTT CCAACTATTG CACTGGAATG GAAGCCTAAA AGCCCTTCGT 
GAAACAAAGT GTTCCCGACA GGAAGTCATC TCCTACTATT CTCAGTATTC TCTAGATGAA 
AAGATGCGCA GCCACATGGC CCTGGACTGG ATCATGAAGG AGCGGGACTC ACCAGGAATT 
GTCTCTCAAG AGCTACGAAT GGCCCTGAGG CAGTTGGAGG AAGCCAGGAA AGCAGGACAA 
GAACTACGGT TTTACAAAGA AAAGAAAGAA ATATTGAGCT TAGCCCTGAC TCAGATCTGC 
AGTGACCCTG ACACTTCCTC ACCCAGTGAT GATCAGCTGA GCCTTACGGC CCTGTGTGGC 
TATCACTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_694966.3
CDS	241..1089
Translation	MDRTLESLRHIIAQVLPHRDPALVFKDLNVVSMLQEFWESKQQQKAAFPSEGVVVYESLPAPGPPFVSYVTLPGGSCFGNFQCCLSRAEARRDAAKVALINSLFNELPSRRITKEFIMESVQEAVASTSGTLDDADDPSTSVGAYHYMLESNMGKTMLEFQELMTIFQLLHWNGSLKALRETKCSRQEVISYYSQYSLDEKMRSHMALDWIMKERDSPGIVSQELRMALRQLEEARKAGQELRFYKEKKEILSLALTQICSDPDTSSPSDDQLSLTALCGYH

Target ORF information:

RefSeq Version	NM_153234.4
Organism	Homo sapiens(human)
Definition	Homo sapiens limb and CNS expressed 1 (LIX1), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_153234.4

ORF Insert Sequence:

ATGGACAGAA CCTTGGAATC TCTGAGACAC ATCATTGCCC AAGTCTTGCC TCACAGAGAT 
CCGGCTCTAG TCTTCAAAGA CTTGAACGTT GTGTCAATGT TACAGGAATT TTGGGAAAGC 
AAGCAGCAGC AGAAGGCTGC ATTCCCAAGT GAAGGTGTGG TGGTCTATGA GTCACTGCCA 
GCTCCTGGGC CTCCCTTTGT GAGTTACGTG ACCCTCCCAG GGGGAAGCTG TTTTGGCAAC 
TTTCAGTGCT GCTTAAGTAG AGCCGAGGCC AGGCGGGATG CAGCTAAAGT GGCCCTGATC 
AACTCCCTCT TCAATGAGCT GCCCTCTCGC AGGATCACCA AGGAATTCAT TATGGAAAGT 
GTTCAGGAAG CAGTAGCCTC CACCAGCGGC ACCTTAGATG ATGCAGATGA CCCCAGCACC 
AGTGTTGGGG CCTATCACTA CATGCTGGAG TCAAACATGG GGAAGACTAT GCTGGAGTTT 
CAGGAGCTGA TGACCATTTT CCAACTATTG CACTGGAATG GAAGCCTAAA AGCCCTTCGT 
GAAACAAAGT GTTCCCGACA GGAAGTCATC TCCTACTATT CTCAGTATTC TCTAGATGAA 
AAGATGCGCA GCCACATGGC CCTGGACTGG ATCATGAAGG AGCGGGACTC ACCAGGAATT 
GTCTCTCAAG AGCTACGAAT GGCCCTGAGG CAGTTGGAGG AAGCCAGGAA AGCAGGACAA 
GAACTACGGT TTTACAAAGA AAAGAAAGAA ATATTGAGCT TAGCCCTGAC TCAGATCTGC 
AGTGACCCTG ACACTTCCTC ACCCAGTGAT GATCAGCTGA GCCTTACGGC CCTGTGTGGC 
TATCACTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Screening of the LIX1 gene in Japanese and Malaysian patients with SMA and/or SMA-like disorder.
Brain & development32(5)385-9(2010 May)
Sasongko TH,Gunadi,Yusoff S,Atif AB,Fatemeh H,Rani A,Marini M,Ab Aziz CB,Zabidi-Hussin ZA,Nishio H,Zilfalil BA

Sequential use of transcriptional profiling, expression quantitative trait mapping, and gene association implicates MMP20 in human kidney aging.
PLoS genetics5(10)e1000685(2009 Oct)
Wheeler HE,Metter EJ,Tanaka T,Absher D,Higgins J,Zahn JM,Wilhelmy J,Davis RW,Singleton A,Myers RM,Ferrucci L,Kim SK

Drosophila lowfat, a novel modulator of Fat signaling.
Development (Cambridge, England)136(19)3223-33(2009 Oct)
Mao Y,Kucuk B,Irvine KD

Candidate screening of the bovine and feline spinal muscular atrophy genes reveals no evidence for involvement in human motor neuron disorders.
Neuromuscular disorders : NMD18(5)394-7(2008 May)
Parkinson NJ,Baumer D,Rose-Morris A,Talbot K

Murine Lix1, a novel marker for substantia nigra, cortical layer 5, and hindbrain structures.
Brain research. Gene expression patterns1(3-4)199-203(2002 Oct)
Moeller C,Yaylaoglu MB,Alvarez-Bolado G,Thaller C,Eichele G

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LIX1 cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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