CHST13 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	CHST13
Entrez Gene ID	166012
Full Name	carbohydrate sulfotransferase 13
Synonyms	C4ST3
General protein information	Preferred Names carbohydrate sulfotransferase 13 Names carbohydrate sulfotransferase 13 C4ST-3 carbohydrate (chondroitin 4) sulfotransferase 13 chondroitin 4-O-sulfotransferase 3 chondroitin 4-sulfotransferase 3
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 3 Map Location: 3q21.3
Summary	The protein encoded by this gene belongs to the sulfotransferase 2 family. It is localized to the golgi membrane, and catalyzes the transfer of sulfate to the C4 hydroxyl of beta-1,4-linked N-acetylgalactosamine (GalNAc) flanked by glucuronic acid residue in chondroitin. Chondroitin sulfate constitutes the predominant proteoglycan present in cartilage and is distributed on the surfaces of many cells and extracellular matrices. [provided by RefSeq, Aug 2011].
Disorder MIM:	610124

mRNA and Protein(s)

mRNA	Protein	Name
NM_152889.2	NP_690849.1	carbohydrate sulfotransferase 13 precursor
NM_152889.3	NP_690849.1	carbohydrate sulfotransferase 13 precursor

Pathways from BioSystems

Homologies

Homo sapiens (human)	CHST13	NP_690849.1
Rattus norvegicus (Norway rat)	Chst13	NP_001178903.1
Bos taurus (cattle)	CHST13	NP_001095549.1
	CHST13	XP_001114334.1
Pan troglodytes (chimpanzee)	CHST13	XP_526449.2
Canis lupus familiaris (dog)	CHST13	XP_005632121.1
Mus musculus (house mouse)	Chst13	NP_082204.1

Gene Ontology
Bibliography

Related articles in PubMed

CHST11/13 Regulate the Metastasis and Chemosensitivity of Human Hepatocellular Carcinoma Cells Via Mitogen-Activated Protein Kinase Pathway.
Zhou H, Li Y, Song X, Zhao Y, Cheng L, Zhao L, Jia L
Digestive diseases and sciences61(7)1972-85(2016 07)

Natural frequency of polymorphisms linked to the chondroitin 4-sulfotransferase genes and its association with placental malaria.
Valente B, Campos PA, do Ros?rio VE, Silveira H
Transactions of the Royal Society of Tropical Medicine and Hygiene104(10)687-9(2010 Oct)

Molecular cloning and characterization of chondroitin-4-O-sulfotransferase-3. A novel member of the HNK-1 family of sulfotransferases.
Kang HG, Evers MR, Xia G, Baenziger JU, Schachner M
The Journal of biological chemistry277(38)34766-72(2002 Sep)

Molecular cloning and expression of two distinct human chondroitin 4-O-sulfotransferases that belong to the HNK-1 sulfotransferase gene family.
Hiraoka N, Nakagawa H, Ong E, Akama TO, Fukuda MN, Fukuda M
The Journal of biological chemistry275(26)20188-96(2000 Jun)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

These results have demonstrated that CHST11 and CHST13 negatively modulate metastasis and drug resistance of HCC cells probably via oncogenic MAPK signal pathway.
Title: CHST11/13 Regulate the Metastasis and Chemosensitivity of Human Hepatocellular Carcinoma Cells Via Mitogen-Activated Protein Kinase Pathway.

Observational study of gene-disease association. (HuGE Navigator)
Title: Natural frequency of polymorphisms linked to the chondroitin 4-sulfotransferase genes and its association with placental malaria.

mol cloning and characterization
Title: Molecular cloning and characterization of chondroitin-4-O-sulfotransferase-3. A novel member of the HNK-1 family of sulfotransferases.

The following CHST13 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the CHST13 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu17778	NM_152889.3 Latest version!	Homo sapiens carbohydrate sulfotransferase 13 (CHST13), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$159.50-$223.30 $319.00
View Old Accession Versions >>
OHu17778	NM_152889.2	Homo sapiens carbohydrate sulfotransferase 13 (CHST13), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$202.30 $289.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

CHST13 ( NM_152889.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_690849.1 Homo sapiens carbohydrate sulfotransferase 13 (CHST13), mRNA.

Price & Availability↑

CloneID	OHu17778
Clone ID Related Accession (Same CDS sequence)	NM_152889.2 , NM_152889.3
Accession Version	NM_152889.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1026bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-10-24
Organism	Homo sapiens(human)
Product	carbohydrate sulfotransferase 13 precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AC024558.21, DR006930.1 and AY120869.1. This sequence is a reference standard in the RefSeqGene project. On May 17, 2019 this sequence version replaced NM_152889.2. ##Evidence-Data-START## Transcript exon combination :: AY120869.1, BC103895.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968540, SAMEA1970526 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000319340.7/ ENSP00000317404.2 RefSeq Select criteria :: based on single protein-coding transcript ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGGGGAGGC GCTGCTGCCG GCGGCGCGTG CTGGCGGCCG CCTGTCTGGG CGCCGCGCTC 
CTGCTCCTAT GCGCCGCGCC CCGCTCCCTG CGCCCGGCAT TTGGAAACAG AGCCCTGGGC 
TCCAGCTGGC TTGGTGGGGA GAAGAGAAGC CCCCTGCAGA AGCTCTATGA CCTGGATCAG 
GACCCGCGCT CGACCCTGGC GAAGGTGCAC CGGCAGCGGC GCGACCTGCT GAACAGCGCC 
TGTAGCCGCC ACTCACGCCG GCAGCGCCTG CTACAGCCGG AGGACCTGCG GCACGTGCTG 
GTGGACGACG CGCATGGCCT GCTCTACTGC TACGTGCCCA AGGTGGCCTG CACCAACTGG 
AAGCGCGTGC TGCTGGCGCT GAGCGGCCAA GCCCGCGGCG ACCCGCGCGC CATCTCCGCG 
CAAGAGGCGC ACGCGCCTGG CCGCCTGCCC TCACTGGCCG ACTTCAGCCC CGCCGAGATC 
AACCGGCGCC TGCGCGCCTA CTTGGCCTTC CTGTTCGTGC GGGAGCCCTT CGAGCGCCTG 
GCATCGGCTT ACCGCAACAA GCTCGCGCGC CCCTACAGCG CCGCCTTCCA GAGGCGCTAC 
GGTGCACGCA TCGTTCAGCG CCTGCGGCCG CGCGCGCTCC CCGACGCCCG GGCCCGCGGC 
CACGACGTGC GCTTCGCGGA GTTCCTGGCC TACCTGCTGG ACCCGCGCAC GCGGCGTGAG 
GAGCCCTTCA ACGAGCACTG GGAGCGCGCG CACGCGCTCT GCCACCCGTG TCGCCTCCGC 
TACGACGTCG TGGGCAAGTT CGAGACGCTG GCGGAGGACG CGGCCTTCGT GCTGGGCCTG 
GCGGGCGCAT CCGACCTGAG CTTCCCTGGG CCGCCGCGGC CCCGGGGAGC CGCCGCCTCC 
CGCGACCTGG CAGCGCGCCT CTTCCGGGAC ATCAGCCCCT TCTACCAGCG GCGCCTCTTC 
GACCTCTACA AGATGGACTT CCTGCTTTTC AACTACTCCG CCCCCTCCTA CCTGCGGCTG 
CTCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_690849.1
CDS	179..1204
Translation	MGRRCCRRRVLAAACLGAALLLLCAAPRSLRPAFGNRALGSSWLGGEKRSPLQKLYDLDQDPRSTLAKVHRQRRDLLNSACSRHSRRQRLLQPEDLRHVLVDDAHGLLYCYVPKVACTNWKRVLLALSGQARGDPRAISAQEAHAPGRLPSLADFSPAEINRRLRAYLAFLFVREPFERLASAYRNKLARPYSAAFQRRYGARIVQRLRPRALPDARARGHDVRFAEFLAYLLDPRTRREEPFNEHWERAHALCHPCRLRYDVVGKFETLAEDAAFVLGLAGASDLSFPGPPRPRGAAASRDLAARLFRDISPFYQRRLFDLYKMDFLLFNYSAPSYLRLL

Target ORF information:

RefSeq Version	NM_152889.3
Organism	Homo sapiens(human)
Definition	Homo sapiens carbohydrate sulfotransferase 13 (CHST13), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_152889.3

ORF Insert Sequence:

ATGGGGAGGC GCTGCTGCCG GCGGCGCGTG CTGGCGGCCG CCTGTCTGGG CGCCGCGCTC 
CTGCTCCTAT GCGCCGCGCC CCGCTCCCTG CGCCCGGCAT TTGGAAACAG AGCCCTGGGC 
TCCAGCTGGC TTGGTGGGGA GAAGAGAAGC CCCCTGCAGA AGCTCTATGA CCTGGATCAG 
GACCCGCGCT CGACCCTGGC GAAGGTGCAC CGGCAGCGGC GCGACCTGCT GAACAGCGCC 
TGTAGCCGCC ACTCACGCCG GCAGCGCCTG CTACAGCCGG AGGACCTGCG GCACGTGCTG 
GTGGACGACG CGCATGGCCT GCTCTACTGC TACGTGCCCA AGGTGGCCTG CACCAACTGG 
AAGCGCGTGC TGCTGGCGCT GAGCGGCCAA GCCCGCGGCG ACCCGCGCGC CATCTCCGCG 
CAAGAGGCGC ACGCGCCTGG CCGCCTGCCC TCACTGGCCG ACTTCAGCCC CGCCGAGATC 
AACCGGCGCC TGCGCGCCTA CTTGGCCTTC CTGTTCGTGC GGGAGCCCTT CGAGCGCCTG 
GCATCGGCTT ACCGCAACAA GCTCGCGCGC CCCTACAGCG CCGCCTTCCA GAGGCGCTAC 
GGTGCACGCA TCGTTCAGCG CCTGCGGCCG CGCGCGCTCC CCGACGCCCG GGCCCGCGGC 
CACGACGTGC GCTTCGCGGA GTTCCTGGCC TACCTGCTGG ACCCGCGCAC GCGGCGTGAG 
GAGCCCTTCA ACGAGCACTG GGAGCGCGCG CACGCGCTCT GCCACCCGTG TCGCCTCCGC 
TACGACGTCG TGGGCAAGTT CGAGACGCTG GCGGAGGACG CGGCCTTCGT GCTGGGCCTG 
GCGGGCGCAT CCGACCTGAG CTTCCCTGGG CCGCCGCGGC CCCGGGGAGC CGCCGCCTCC 
CGCGACCTGG CAGCGCGCCT CTTCCGGGAC ATCAGCCCCT TCTACCAGCG GCGCCTCTTC 
GACCTCTACA AGATGGACTT CCTGCTTTTC AACTACTCCG CCCCCTCCTA CCTGCGGCTG 
CTCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

CHST13 ( NM_152889.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_690849.1 Homo sapiens carbohydrate sulfotransferase 13 (CHST13), mRNA.

Price & Availability↑

CloneID	OHu17778
Clone ID Related Accession (Same CDS sequence)	NM_152889.2 , NM_152889.3
Accession Version	NM_152889.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1026bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-02-22
Organism	Homo sapiens(human)
Product	carbohydrate sulfotransferase 13 precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DR006930.1 and AY120869.1. This sequence is a reference standard in the RefSeqGene project. On Aug 30, 2011 this sequence version replaced NM_152889.1. ##Evidence-Data-START## Transcript exon combination :: AY120869.1, BC103895.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968540, SAMEA1970526 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGGGAGGC GCTGCTGCCG GCGGCGCGTG CTGGCGGCCG CCTGTCTGGG CGCCGCGCTC 
CTGCTCCTAT GCGCCGCGCC CCGCTCCCTG CGCCCGGCAT TTGGAAACAG AGCCCTGGGC 
TCCAGCTGGC TTGGTGGGGA GAAGAGAAGC CCCCTGCAGA AGCTCTATGA CCTGGATCAG 
GACCCGCGCT CGACCCTGGC GAAGGTGCAC CGGCAGCGGC GCGACCTGCT GAACAGCGCC 
TGTAGCCGCC ACTCACGCCG GCAGCGCCTG CTACAGCCGG AGGACCTGCG GCACGTGCTG 
GTGGACGACG CGCATGGCCT GCTCTACTGC TACGTGCCCA AGGTGGCCTG CACCAACTGG 
AAGCGCGTGC TGCTGGCGCT GAGCGGCCAA GCCCGCGGCG ACCCGCGCGC CATCTCCGCG 
CAAGAGGCGC ACGCGCCTGG CCGCCTGCCC TCACTGGCCG ACTTCAGCCC CGCCGAGATC 
AACCGGCGCC TGCGCGCCTA CTTGGCCTTC CTGTTCGTGC GGGAGCCCTT CGAGCGCCTG 
GCATCGGCTT ACCGCAACAA GCTCGCGCGC CCCTACAGCG CCGCCTTCCA GAGGCGCTAC 
GGTGCACGCA TCGTTCAGCG CCTGCGGCCG CGCGCGCTCC CCGACGCCCG GGCCCGCGGC 
CACGACGTGC GCTTCGCGGA GTTCCTGGCC TACCTGCTGG ACCCGCGCAC GCGGCGTGAG 
GAGCCCTTCA ACGAGCACTG GGAGCGCGCG CACGCGCTCT GCCACCCGTG TCGCCTCCGC 
TACGACGTCG TGGGCAAGTT CGAGACGCTG GCGGAGGACG CGGCCTTCGT GCTGGGCCTG 
GCGGGCGCAT CCGACCTGAG CTTCCCTGGG CCGCCGCGGC CCCGGGGAGC CGCCGCCTCC 
CGCGACCTGG CAGCGCGCCT CTTCCGGGAC ATCAGCCCCT TCTACCAGCG GCGCCTCTTC 
GACCTCTACA AGATGGACTT CCTGCTTTTC AACTACTCCG CCCCCTCCTA CCTGCGGCTG 
CTCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_690849.1
CDS	46..1071
Translation	MGRRCCRRRVLAAACLGAALLLLCAAPRSLRPAFGNRALGSSWLGGEKRSPLQKLYDLDQDPRSTLAKVHRQRRDLLNSACSRHSRRQRLLQPEDLRHVLVDDAHGLLYCYVPKVACTNWKRVLLALSGQARGDPRAISAQEAHAPGRLPSLADFSPAEINRRLRAYLAFLFVREPFERLASAYRNKLARPYSAAFQRRYGARIVQRLRPRALPDARARGHDVRFAEFLAYLLDPRTRREEPFNEHWERAHALCHPCRLRYDVVGKFETLAEDAAFVLGLAGASDLSFPGPPRPRGAAASRDLAARLFRDISPFYQRRLFDLYKMDFLLFNYSAPSYLRLL

Target ORF information:

RefSeq Version	NM_152889.2
Organism	Homo sapiens(human)
Definition	Homo sapiens carbohydrate sulfotransferase 13 (CHST13), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_152889.2

ORF Insert Sequence:

ATGGGGAGGC GCTGCTGCCG GCGGCGCGTG CTGGCGGCCG CCTGTCTGGG CGCCGCGCTC 
CTGCTCCTAT GCGCCGCGCC CCGCTCCCTG CGCCCGGCAT TTGGAAACAG AGCCCTGGGC 
TCCAGCTGGC TTGGTGGGGA GAAGAGAAGC CCCCTGCAGA AGCTCTATGA CCTGGATCAG 
GACCCGCGCT CGACCCTGGC GAAGGTGCAC CGGCAGCGGC GCGACCTGCT GAACAGCGCC 
TGTAGCCGCC ACTCACGCCG GCAGCGCCTG CTACAGCCGG AGGACCTGCG GCACGTGCTG 
GTGGACGACG CGCATGGCCT GCTCTACTGC TACGTGCCCA AGGTGGCCTG CACCAACTGG 
AAGCGCGTGC TGCTGGCGCT GAGCGGCCAA GCCCGCGGCG ACCCGCGCGC CATCTCCGCG 
CAAGAGGCGC ACGCGCCTGG CCGCCTGCCC TCACTGGCCG ACTTCAGCCC CGCCGAGATC 
AACCGGCGCC TGCGCGCCTA CTTGGCCTTC CTGTTCGTGC GGGAGCCCTT CGAGCGCCTG 
GCATCGGCTT ACCGCAACAA GCTCGCGCGC CCCTACAGCG CCGCCTTCCA GAGGCGCTAC 
GGTGCACGCA TCGTTCAGCG CCTGCGGCCG CGCGCGCTCC CCGACGCCCG GGCCCGCGGC 
CACGACGTGC GCTTCGCGGA GTTCCTGGCC TACCTGCTGG ACCCGCGCAC GCGGCGTGAG 
GAGCCCTTCA ACGAGCACTG GGAGCGCGCG CACGCGCTCT GCCACCCGTG TCGCCTCCGC 
TACGACGTCG TGGGCAAGTT CGAGACGCTG GCGGAGGACG CGGCCTTCGT GCTGGGCCTG 
GCGGGCGCAT CCGACCTGAG CTTCCCTGGG CCGCCGCGGC CCCGGGGAGC CGCCGCCTCC 
CGCGACCTGG CAGCGCGCCT CTTCCGGGAC ATCAGCCCCT TCTACCAGCG GCGCCTCTTC 
GACCTCTACA AGATGGACTT CCTGCTTTTC AACTACTCCG CCCCCTCCTA CCTGCGGCTG 
CTCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

CHST11/13 Regulate the Metastasis and Chemosensitivity of Human Hepatocellular Carcinoma Cells Via Mitogen-Activated Protein Kinase Pathway.
Digestive diseases and sciences61(7)1972-85(2016 07)
Zhou H,Li Y,Song X,Zhao Y,Cheng L,Zhao L,Jia L

Natural frequency of polymorphisms linked to the chondroitin 4-sulfotransferase genes and its association with placental malaria.
Transactions of the Royal Society of Tropical Medicine and Hygiene104(10)687-9(2010 Oct)
Valente B,Campos PA,do Ros?rio VE,Silveira H

Molecular cloning and characterization of chondroitin-4-O-sulfotransferase-3. A novel member of the HNK-1 family of sulfotransferases.
The Journal of biological chemistry277(38)34766-72(2002 Sep)
Kang HG,Evers MR,Xia G,Baenziger JU,Schachner M

Molecular cloning and expression of two distinct human chondroitin 4-O-sulfotransferases that belong to the HNK-1 sulfotransferase gene family.
The Journal of biological chemistry275(26)20188-96(2000 Jun)
Hiraoka N,Nakagawa H,Ong E,Akama TO,Fukuda MN,Fukuda M

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CHST13 cDNA ORF clone, Homo sapiens(human)

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gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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