EID2 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	EID2
Entrez Gene ID	163126
Full Name	EP300 interacting inhibitor of differentiation 2
Synonyms	CRI2,EID-2
General protein information	Preferred Names EP300 interacting inhibitor of differentiation 2 Names EP300-interacting inhibitor of differentiation 2 CREBBP/EP300 inhibitor 2 CREBBP/EP300 inhibitory protein 2 E1A like inhibitor of differentiation 2 EID-1-like inhibitor of differentiation 2
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 19 Map Location: 19q13.2
Disorder MIM:	609773

mRNA and Protein(s)

mRNA	Protein	Name
NM_153232.3	NP_694964.3	EP300-interacting inhibitor of differentiation 2
NM_153232.4	NP_694964.3	EP300-interacting inhibitor of differentiation 2

Pathways from BioSystems

Homologies

Homo sapiens (human)	EID2	NP_694964.3
Pan troglodytes (chimpanzee)	EID2	XP_003316397.1
	EID2	XP_001101216.1
Bos taurus (cattle)	EID2	NP_001071517.1
Canis lupus familiaris (dog)	EID2	XP_855345.2
Mus musculus (house mouse)	Eid2	NP_940817.1
Rattus norvegicus (Norway rat)	Eid2	XP_001064863.2

Gene Ontology
Bibliography

Related articles in PubMed

A novel EID family member, EID-3, inhibits differentiation and forms a homodimer or heterodimer with EID-2.
Sasajima Y, Tanaka H, Miyake S, Yuasa Y
Biochemical and biophysical research communications333(3)969-75(2005 Aug)

A novel E1A-like inhibitor of differentiation (EID) family member, EID-2, suppresses transforming growth factor (TGF)-beta signaling by blocking TGF-beta-induced formation of Smad3-Smad4 complexes.
Lee HJ, Lee JK, Miyake S, Kim SJ
The Journal of biological chemistry279(4)2666-72(2004 Jan)

EID-2, a novel member of the EID family of p300-binding proteins inhibits transactivation by MyoD.
Ji A, Dao D, Chen J, MacLellan WR
Gene31835-43(2003 Oct)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

EID-2 may function as an endogenous suppressor of TGF-beta signaling
Title: A novel E1A-like inhibitor of differentiation (EID) family member, EID-2, suppresses transforming growth factor (TGF)-beta signaling by blocking TGF-beta-induced formation of Smad3-Smad4 complexes.

The following EID2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the EID2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu29340	NM_153232.4 Latest version!	Homo sapiens EP300 interacting inhibitor of differentiation 2 (EID2), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$188.30 $269.00
View Old Accession Versions >>
OHu29340	NM_153232.3	Homo sapiens EP300 interacting inhibitor of differentiation 2 (EID2), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$188.30 $269.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

EID2 ( NM_153232.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_694964.3 Homo sapiens EP300 interacting inhibitor of differentiation 2 (EID2), mRNA.

Price & Availability↑

CloneID	OHu29340
Clone ID Related Accession (Same CDS sequence)	NM_153232.3 , NM_153232.4
Accession Version	NM_153232.3	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 711bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-02-16
Organism	Homo sapiens(human)
Product	EP300-interacting inhibitor of differentiation 2
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AK128468.1 and BC030137.2. On May 11, 2005 this sequence version replaced NM_153232.2. ##Evidence-Data-START## Transcript is intronless :: BC030137.2 [ECO:0000345] ##Evidence-Data-END##

ATGTCCAAGC TGCCCGCAGA CAGCAGTGTC CCGCAGACAG GCGCGGCGAA TGGTGACAGA 
GACGTCCCGC AGGCGGAGGT AGGCCGCGGG AGGCGGGAGC CGGCCCCGGC ACAGCCTGAG 
GAGGCCGGGG AAGGCGCGAT GGCGGCGGCC AGGGGAGGCC CGGTGCCGGC GGCCAGGGAA 
GGTCGGATGG CGGCGGCCAG GGCAGCCCCG GCGGCGGCAG CCAGGGGAGC CCCGGTGGCA 
GCGGCGGCGT TGGCCAGGGC AGCCGCGGCG GGCAGGGAAA GCCCGGCGGC GGCGGCGGCC 
AGGGAAGCCC GGATGGCGGA GGTCGCCCGC TTGCTGGGGG AGCCAGTGGA CGAAGAGGGT 
CCCGAGGGCA GGCCCAGGTC CAGACACGGG AACGGAGGCC TGGCTGCGTT GCCCTATCTC 
CGTCTCCGCC ACCCACTTAG CGTTTTAGGC ATCAATTACC AGCAGTTTCT CCGCCACTAT 
CTGGAAAATT ACCCGATTGC TCCCGGCAGA ATACAAGAGC TTGAAGAACG CCGCAGGCGA 
TTCGTGGAAG CCTGCAGAGC AAGGGAAGCA GCGTTTGATG CCGAATATCA GCGAAATCCT 
CACAGGGTGG ACCTCGATAT TTTAACCTTT ACGATAGCTC TGACTGCCTC TGAAGTTATC 
AACCCTCTGA TAGAAGAACT TGGTTGCGAT AAGTTTATCA ATAGAGAATA G

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_694964.3
CDS	120..830
Translation	MSKLPADSSVPQTGAANGDRDVPQAEVGRGRREPAPAQPEEAGEGAMAAARGGPVPAAREGRMAAARAAPAAAARGAPVAAAALARAAAAGRESPAAAAAREARMAEVARLLGEPVDEEGPEGRPRSRHGNGGLAALPYLRLRHPLSVLGINYQQFLRHYLENYPIAPGRIQELEERRRRFVEACRAREAAFDAEYQRNPHRVDLDILTFTIALTASEVINPLIEELGCDKFINRE

Target ORF information:

RefSeq Version	NM_153232.3
Organism	Homo sapiens(human)
Definition	Homo sapiens EP300 interacting inhibitor of differentiation 2 (EID2), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_153232.3

ORF Insert Sequence:

ATGTCCAAGC TGCCCGCAGA CAGCAGTGTC CCGCAGACAG GCGCGGCGAA TGGTGACAGA 
GACGTCCCGC AGGCGGAGGT AGGCCGCGGG AGGCGGGAGC CGGCCCCGGC ACAGCCTGAG 
GAGGCCGGGG AAGGCGCGAT GGCGGCGGCC AGGGGAGGCC CGGTGCCGGC GGCCAGGGAA 
GGTCGGATGG CGGCGGCCAG GGCAGCCCCG GCGGCGGCAG CCAGGGGAGC CCCGGTGGCA 
GCGGCGGCGT TGGCCAGGGC AGCCGCGGCG GGCAGGGAAA GCCCGGCGGC GGCGGCGGCC 
AGGGAAGCCC GGATGGCGGA GGTCGCCCGC TTGCTGGGGG AGCCAGTGGA CGAAGAGGGT 
CCCGAGGGCA GGCCCAGGTC CAGACACGGG AACGGAGGCC TGGCTGCGTT GCCCTATCTC 
CGTCTCCGCC ACCCACTTAG CGTTTTAGGC ATCAATTACC AGCAGTTTCT CCGCCACTAT 
CTGGAAAATT ACCCGATTGC TCCCGGCAGA ATACAAGAGC TTGAAGAACG CCGCAGGCGA 
TTCGTGGAAG CCTGCAGAGC AAGGGAAGCA GCGTTTGATG CCGAATATCA GCGAAATCCT 
CACAGGGTGG ACCTCGATAT TTTAACCTTT ACGATAGCTC TGACTGCCTC TGAAGTTATC 
AACCCTCTGA TAGAAGAACT TGGTTGCGAT AAGTTTATCA ATAGAGAATA G

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

EID2 ( NM_153232.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_694964.3 Homo sapiens EP300 interacting inhibitor of differentiation 2 (EID2), mRNA.

Price & Availability↑

CloneID	OHu29340
Clone ID Related Accession (Same CDS sequence)	NM_153232.3 , NM_153232.4
Accession Version	NM_153232.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 711bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-10-20
Organism	Homo sapiens(human)
Product	EP300-interacting inhibitor of differentiation 2
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BC030137.2 and AC011500.7. On May 17, 2019 this sequence version replaced NM_153232.3. ##Evidence-Data-START## Transcript is intronless :: ERR279825.5101.1, BC030137.2 [ECO:0000345] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000390658.4/ ENSP00000375073.2 RefSeq Select criteria :: based on single protein-coding transcript ##RefSeq-Attributes-END##

ATGTCCAAGC TGCCCGCAGA CAGCAGTGTC CCGCAGACAG GCGCGGCGAA TGGTGACAGA 
GACGTCCCGC AGGCGGAGGT AGGCCGCGGG AGGCGGGAGC CGGCCCCGGC ACAGCCTGAG 
GAGGCCGGGG AAGGCGCGAT GGCGGCGGCC AGGGGAGGCC CGGTGCCGGC GGCCAGGGAA 
GGTCGGATGG CGGCGGCCAG GGCAGCCCCG GCGGCGGCAG CCAGGGGAGC CCCGGTGGCA 
GCGGCGGCGT TGGCCAGGGC AGCCGCGGCG GGCAGGGAAA GCCCGGCGGC GGCGGCGGCC 
AGGGAAGCCC GGATGGCGGA GGTCGCCCGC TTGCTGGGGG AGCCAGTGGA CGAAGAGGGT 
CCCGAGGGCA GGCCCAGGTC CAGACACGGG AACGGAGGCC TGGCTGCGTT GCCCTATCTC 
CGTCTCCGCC ACCCACTTAG CGTTTTAGGC ATCAATTACC AGCAGTTTCT CCGCCACTAT 
CTGGAAAATT ACCCGATTGC TCCCGGCAGA ATACAAGAGC TTGAAGAACG CCGCAGGCGA 
TTCGTGGAAG CCTGCAGAGC AAGGGAAGCA GCGTTTGATG CCGAATATCA GCGAAATCCT 
CACAGGGTGG ACCTCGATAT TTTAACCTTT ACGATAGCTC TGACTGCCTC TGAAGTTATC 
AACCCTCTGA TAGAAGAACT TGGTTGCGAT AAGTTTATCA ATAGAGAATA G

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_694964.3
CDS	83..793
Translation	MSKLPADSSVPQTGAANGDRDVPQAEVGRGRREPAPAQPEEAGEGAMAAARGGPVPAAREGRMAAARAAPAAAARGAPVAAAALARAAAAGRESPAAAAAREARMAEVARLLGEPVDEEGPEGRPRSRHGNGGLAALPYLRLRHPLSVLGINYQQFLRHYLENYPIAPGRIQELEERRRRFVEACRAREAAFDAEYQRNPHRVDLDILTFTIALTASEVINPLIEELGCDKFINRE

Target ORF information:

RefSeq Version	NM_153232.4
Organism	Homo sapiens(human)
Definition	Homo sapiens EP300 interacting inhibitor of differentiation 2 (EID2), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_153232.4

ORF Insert Sequence:

ATGTCCAAGC TGCCCGCAGA CAGCAGTGTC CCGCAGACAG GCGCGGCGAA TGGTGACAGA 
GACGTCCCGC AGGCGGAGGT AGGCCGCGGG AGGCGGGAGC CGGCCCCGGC ACAGCCTGAG 
GAGGCCGGGG AAGGCGCGAT GGCGGCGGCC AGGGGAGGCC CGGTGCCGGC GGCCAGGGAA 
GGTCGGATGG CGGCGGCCAG GGCAGCCCCG GCGGCGGCAG CCAGGGGAGC CCCGGTGGCA 
GCGGCGGCGT TGGCCAGGGC AGCCGCGGCG GGCAGGGAAA GCCCGGCGGC GGCGGCGGCC 
AGGGAAGCCC GGATGGCGGA GGTCGCCCGC TTGCTGGGGG AGCCAGTGGA CGAAGAGGGT 
CCCGAGGGCA GGCCCAGGTC CAGACACGGG AACGGAGGCC TGGCTGCGTT GCCCTATCTC 
CGTCTCCGCC ACCCACTTAG CGTTTTAGGC ATCAATTACC AGCAGTTTCT CCGCCACTAT 
CTGGAAAATT ACCCGATTGC TCCCGGCAGA ATACAAGAGC TTGAAGAACG CCGCAGGCGA 
TTCGTGGAAG CCTGCAGAGC AAGGGAAGCA GCGTTTGATG CCGAATATCA GCGAAATCCT 
CACAGGGTGG ACCTCGATAT TTTAACCTTT ACGATAGCTC TGACTGCCTC TGAAGTTATC 
AACCCTCTGA TAGAAGAACT TGGTTGCGAT AAGTTTATCA ATAGAGAATA G

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

A novel EID family member, EID-3, inhibits differentiation and forms a homodimer or heterodimer with EID-2.
Biochemical and biophysical research communications333(3)969-75(2005 Aug)
Sasajima Y,Tanaka H,Miyake S,Yuasa Y

A novel E1A-like inhibitor of differentiation (EID) family member, EID-2, suppresses transforming growth factor (TGF)-beta signaling by blocking TGF-beta-induced formation of Smad3-Smad4 complexes.
The Journal of biological chemistry279(4)2666-72(2004 Jan)
Lee HJ,Lee JK,Miyake S,Kim SJ

EID-2, a novel member of the EID family of p300-binding proteins inhibits transactivation by MyoD.
Gene31835-43(2003 Oct)
Ji A,Dao D,Chen J,MacLellan WR