Gene Symbol | OTUD7A |
Entrez Gene ID | 161725 |
Full Name | OTU deubiquitinase 7A |
Synonyms | C15orf16,C16ORF15,CEZANNE2,OTUD7 |
General protein information |
|
Gene Type | protein-coding |
Organism | Homo sapiens(human) |
Genome | |
Summary | The protein encoded by this gene is a deubiquitinizing enzyme and possible tumor suppressor. The encoded protein acts on TNF receptor associated factor 6 (TRAF6) to control nuclear factor kappa B expression. However, this gene is downregulated by SNAIL1 in hepatocellular carcinoma cells, contributing to their progression and malignancy. [provided by RefSeq, Aug 2016]. |
Disorder MIM: |