MAMDC4 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	MAMDC4
Entrez Gene ID	158056
Full Name	MAM domain containing 4
Synonyms	AEGP
General protein information	Preferred Names MAM domain containing 4 Names apical endosomal glycoprotein MAM domain-containing protein 4 apical early endosomal glycoprotein endotubin
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 9 Map Location: 9q34.3
Disorder MIM:	617208

mRNA and Protein(s)

mRNA	Protein	Name
NM_206920.3	NP_996803.2	apical endosomal glycoprotein precursor
NM_206920.2	NP_996803.2	apical endosomal glycoprotein precursor

Pathways from BioSystems

Homologies

Homo sapiens (human)	MAMDC4	NP_996803.2
Canis lupus familiaris (dog)	MAMDC4	XP_005625136.1
Rattus norvegicus (Norway rat)	Mamdc4	NP_665711.1
Gallus gallus (chicken)	MAMDC4	XP_004945772.1
Danio rerio (zebrafish)	LOC797166	XP_001337624.4
Xenopus tropicalis (tropical clawed frog)	mamdc4	XP_002940785.2
Pan troglodytes (chimpanzee)	MAMDC4	XP_528464.3
	MAMDC4	XP_002799962.1
Bos taurus (cattle)	MAMDC4	NP_001137345.1
Mus musculus (house mouse)	Mamdc4	NP_001074668.2

Gene Ontology
Bibliography

Related articles in PubMed

Private rare deletions in SEC16A and MAMDC4 may represent novel pathogenic variants in familial axial spondyloarthritis.
O'Rielly DD, Uddin M, Codner D, Hayley M, Zhou J, Pena-Castillo L, Mostafa AA, Hasan SM, Liu W, Haroon N, Inman R, Rahman P
Annals of the rheumatic diseases75(4)772-9(2016 Apr)

The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment.
Clark HF, Gurney AL, Abaya E, Baker K, Baldwin D, Brush J, Chen J, Chow B, Chui C, Crowley C, Currell B, Deuel B, Dowd P, Eaton D, Foster J, Grimaldi C, Gu Q, Hass PE, Heldens S, Huang A, Kim HS, Klimowski L, Jin Y, Johnson S, Lee J, Lewis L, Liao D, Mark M, Robbie E, Sanchez C, Schoenfeld J, Seshagiri S, Simmons L, Singh J, Smith V, Stinson J, Vagts A, Vandlen R, Watanabe C, Wieand D, Woods K, Xie MH, Yansura D, Yi S, Yu G, Yuan J, Zhang M, Zhang Z, Goddard A, Wood WI, Godowski P, Gray A
Genome research13(10)2265-70(2003 Oct)

Molecular characterization of an apical early endosomal glycoprotein from developing rat intestinal epithelial cells.
Speelman BA, Allen K, Grounds TL, Neutra MR, Kirchhausen T, Wilson JM
The Journal of biological chemistry270(4)1583-8(1995 Jan)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Results suggest that it is the presence of rare syntenic SEC16A and MAMDC4 deletions that increases susceptibility to axial spondyloarthritis in family members who carry the HLA-B*27 allele.
Title: Private rare deletions in SEC16A and MAMDC4 may represent novel pathogenic variants in familial axial spondyloarthritis.

PMID:7829488 describes studies in rat, however, the human MAMDC4 gene product appears to be a homolog of rat apical early endosomal glycoprotein.
Title: Molecular characterization of an apical early endosomal glycoprotein from developing rat intestinal epithelial cells.

The following MAMDC4 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the MAMDC4 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu29009	NM_206920.3 Latest version!	Homo sapiens MAM domain containing 4 (MAMDC4), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$574.50-$804.30 $1149.00
View Old Accession Versions >>
OHu29009	NM_206920.2	Homo sapiens MAM domain containing 4 (MAMDC4), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$574.50-$804.30 $1149.00
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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

MAMDC4 ( NM_206920.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_996803.2 Homo sapiens MAM domain containing 4 (MAMDC4), mRNA.

Price & Availability↑

CloneID	OHu29009
Clone ID Related Accession (Same CDS sequence)	NM_206920.3 , NM_206920.2
Accession Version	NM_206920.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 3414bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-05-01
Organism	Homo sapiens(human)
Product	apical endosomal glycoprotein precursor
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AL355987.31, AY358419.1, BF339007.1 and BQ270782.1. On Nov 23, 2018 this sequence version replaced NM_206920.2. ##Evidence-Data-START## Transcript exon combination :: AY358419.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968968, SAMEA2145893 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000317446.7/ ENSP00000319388.2 RefSeq Select criteria :: based on single protein-coding transcript ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGCCTCTGT CCAGCCACCT GCTGCCCGCC TTGGTCCTGT TCCTGGCAGG GTCCTCAGGC 
TGGGCCTGGG TCCCCAACCA CTGCAGGAGC CCTGGCCAGG CCGTGTGCAA CTTCGTGTGT 
GACTGCAGGG ACTGCTCAGA TGAGGCCCAG TGTGGTTACC ACGGGGCCTC GCCCACCCTG 
GGCGCCCCCT TCGCCTGTGA CTTCGAGCAG GACCCCTGCG GCTGGCGGGA CATTAGTACC 
TCAGGCTACA GCTGGCTCCG AGACAGGGCA GGGGCCGCAC TGGAGGGTCC TGGGCCTCAC 
TCAGACCACA CACTGGGCAC CGACTTGGGC TGGTACATGG CCGTTGGAAC CCACCGAGGG 
AAAGAGGCAT CCACCGCAGC CCTGCGCTCG CCAACCCTGC GAGAGGCAGC CTCCTCTTGC 
AAGCTGAGGC TCTGGTACCA CGCGGCCTCT GGAGATGTGG CTGAACTGCG GGTGGAGCTG 
ACCCATGGCG CAGAGACCCT GACCCTGTGG CAGAGCACAG GGCCCTGGGG CCCTGGCTGG 
CAGGAGTTGG CAGTGACCAC AGGCCGCATC CGGGGTGACT TCCGAGTGAC CTTCTCTGCC 
ACCCGAAATG CCACCCACAG GGGCGCTGTG GCTCTAGATG ACCTAGAGTT CTGGGACTGT 
GGTCTGCCCA CCCCCCAGGC CAACTGTCCC CCGGGACACC ACCACTGCCA GAACAAGGTC 
TGCGTGGAGC CCCAGCAGCT GTGCGACGGG GAAGACAACT GCGGGGACCT GTCTGATGAG 
AACCCACTCA CCTGTGGCCG CCACATAGCC ACCGACTTTG AGACAGGCCT GGGCCCATGG 
AACCGCTCGG AAGGCTGGTC CCGGAACCAC CGCGCTGGTG GTCCTGAGCG CCCCTCCTGG 
CCACGCCGTG ACCACAGCCG GAACAGTGCA CAGGGCTCCT TCCTGGTCTC CGTGGCCGAG 
CCTGGCACCC CTGCTATACT CTCCAGCCCC GAATTCCAAG CCTCAGGCAC CTCCAACTGC 
TCGCTGGTCT TCTATCAGTA CCTGAGTGGG TCTGAGGCTG GCTGCCTCCA GCTGTTCCTG 
CAGACTCTGG GGCCCGGCGC CCCCCGGGCC CCCGTCCTGC TGCGGAGGCG CCGAGGGGAG 
CTGGGGACCG CCTGGGTCCG AGACCGTGTT GACATCCAGA GCGCCTACCC CTTCCAGATC 
CTCCTGGCCG GGCAGACAGG CCCGGGGGGC GTCGTGGGTC TGGACGACCT CATCCTGTCT 
GACCACTGCA GACCAGTCTC GGAGGTGTCC ACCCTGCAGC CGCTGCCTCC TGGGCCCCGG 
GCCCCAGCCC CCCAGCCCCT GCCGCCCAGC TCGCGGCTCC AGGATTCCTG CAAGCAGGGG 
CATCTTGCCT GCGGGGACCT GTGTGTGCCC CCGGAACAAC TGTGTGACTT CGAGGAGCAG 
TGCGCAGGGG GCGAGGACGA GCAGGCCTGT GGCACCACAG ACTTTGAGTC CCCCGAGGCT 
GGGGGCTGGG AGGACGCCAG CGTGGGGCGG CTGCAGTGGC GGCGTGTCTC AGCCCAGGAG 
AGCCAGGGGT CCAGTGCAGC TGCTGCTGGG CACTTCCTGT CTCTGCAGCG GGCCTGGGGG 
CAGCTAGGCG CTGAGGCCCG GGTCCTCACA CCCCTCCTTG GCCCTTCTGG CCCCAGCTGT 
GAACTCCACC TGGCTTATTA TTTACAGAGC CAGCCCCGAG AGGTCTCCTG TAACTTTGAG 
CGGGACACAT GCAGCTGGTA CCCAGGCCAC CTCTCAGACA CACACTGGCG CTGGGTGGAG 
AGCCGCGGCC CTGACCACGA CCACACCACA GGCCAAGGCC ACTTTGTGCT CCTGGACCCC 
ACAGACCCCC TGGCCTGGGG CCACAGTGCC CACCTGCTCT CCAGGCCCCA GGTGCCAGCA 
GCACCCACGG AGTGTCTCAG CTTCTGGTAC CACCTCCATG GGCCCCAGAT TGGGACTCTG 
CGCCTAGCCA TGAGACGGGA AGGGGAGGAG ACACACCTGT GGTCGCGGTC AGGCACCCAG 
GGCAACCGCT GGCACGAGGC CTGGGCCACC CTTTCCCACC AGCCTGGCTC CCATGCCCAG 
TACCAGCTGC TGTTCGAGGG CCTCCGGGAC GGATACCACG GCACCATGGC GCTGGACGAT 
GTGGCCGTGC GGCCGGGCCC CTGCTGGGCC CCTAATTACT GCTCCTTTGA GGACTCAGAC 
TGCGGCTTCT CCCCTGGAGG CCAAGGTCTC TGGAGGCGGC AGGCCAATGC CTCGGGCCAT 
GCTGCCTGGG GCCCCCCAAC AGACCATACC ACTGAGACAG CCCAAGGGCA CTACATGGTG 
GTGGACACAA GCCCAGACGC ACTACCCCGG GGCCAGACGG CCTCCCTGAC CTCCAAGGAG 
CACAGGCCCC TGGCCCAGCC TGCTTGTCTG ACCTTCTGGT ACCACGGGAG CCTCCGCAGC 
CCAGGCACCC TGCGGGTCTA CCTGGAGGAG CGCGGGAGGC ACCAGGTGCT CAGCCTCAGT 
GCCCACGGCG GGCTTGCCTG GCGCCTGGGC AGCATGGACG TGCAGGCCGA GCGAGCCTGG 
AGGGTGGTGT TTGAGGCAGT GGCCGCAGGC GTGGCACACT CCTACGTGGC TCTGGATGAT 
CTGCTCCTCC AGGACGGGCC CTGCCCTCAG CCAGGTTCCT GTGATTTTGA GTCTGGCCTG 
TGTGGCTGGA GCCACCTGGC CTGGCCCGGC CTGGGCGGAT ACAGCTGGGA CTGGGGCGGG 
GGAGCCACCC CCTCTCGTTA CCCCCAGCCC CCTGTGGACC ACACCCTGGG CACAGAGGCA 
GGCCACTTTG CCTTCTTTGA AACTGGCGTG CTGGGCCCCG GGGGCCGGGC CGCCTGGCTG 
CGCAGCGAGC CTCTGCCGGC CACCCCAGCC TCCTGCCTCC GCTTCTGGTA CCACATGGGT 
TTTCCTGAGC ACTTCTACAA GGGGGAGCTG AAGGTACTGC TGCACAGTGC TCAGGGCCAG 
CTGGCTGTGT GGGGCGCAGG CGGGCATCGG CGGCACCAGT GGCTGGAGGC CCAGGTGGAG 
GTAGCCAGTG CCAAGGAGTT CCAGATCGTG TTTGAAGCCA CTCTGGGCGG CCAGCCAGCC 
CTGGGGCCCA TTGCCCTGGA TGACGTGGAG TATCTGGCTG GGCAGCATTG CCAGCAGCCT 
GCCCCCAGCC CGGGGAACAC AGCCGCACCC GGGTCTGTGC CAGCTGTGGT TGGCAGTGCC 
CTCCTATTGC TCATGCTCCT GGTGCTGCTG GGACTTGGGG GACGGCGCTG GCTGCAGAAG 
AAGGGGAGCT GCCCCTTCCA GAGCAACACA GAGGCCACAG CCCCTGGCTT TGACAACATC 
CTTTTCAATG CGGATGGTGT CACCCTCCCG GCATCTGTCA CCAGTGATCC GTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_996803.2
CDS	72..3485
Translation	MPLSSHLLPALVLFLAGSSGWAWVPNHCRSPGQAVCNFVCDCRDCSDEAQCGYHGASPTLGAPFACDFEQDPCGWRDISTSGYSWLRDRAGAALEGPGPHSDHTLGTDLGWYMAVGTHRGKEASTAALRSPTLREAASSCKLRLWYHAASGDVAELRVELTHGAETLTLWQSTGPWGPGWQELAVTTGRIRGDFRVTFSATRNATHRGAVALDDLEFWDCGLPTPQANCPPGHHHCQNKVCVEPQQLCDGEDNCGDLSDENPLTCGRHIATDFETGLGPWNRSEGWSRNHRAGGPERPSWPRRDHSRNSAQGSFLVSVAEPGTPAILSSPEFQASGTSNCSLVFYQYLSGSEAGCLQLFLQTLGPGAPRAPVLLRRRRGELGTAWVRDRVDIQSAYPFQILLAGQTGPGGVVGLDDLILSDHCRPVSEVSTLQPLPPGPRAPAPQPLPPSSRLQDSCKQGHLACGDLCVPPEQLCDFEEQCAGGEDEQACGTTDFESPEAGGWEDASVGRLQWRRVSAQESQGSSAAAAGHFLSLQRAWGQLGAEARVLTPLLGPSGPSCELHLAYYLQSQPREVSCNFERDTCSWYPGHLSDTHWRWVESRGPDHDHTTGQGHFVLLDPTDPLAWGHSAHLLSRPQVPAAPTECLSFWYHLHGPQIGTLRLAMRREGEETHLWSRSGTQGNRWHEAWATLSHQPGSHAQYQLLFEGLRDGYHGTMALDDVAVRPGPCWAPNYCSFEDSDCGFSPGGQGLWRRQANASGHAAWGPPTDHTTETAQGHYMVVDTSPDALPRGQTASLTSKEHRPLAQPACLTFWYHGSLRSPGTLRVYLEERGRHQVLSLSAHGGLAWRLGSMDVQAERAWRVVFEAVAAGVAHSYVALDDLLLQDGPCPQPGSCDFESGLCGWSHLAWPGLGGYSWDWGGGATPSRYPQPPVDHTLGTEAGHFAFFETGVLGPGGRAAWLRSEPLPATPASCLRFWYHMGFPEHFYKGELKVLLHSAQGQLAVWGAGGHRRHQWLEAQVEVASAKEFQIVFEATLGGQPALGPIALDDVEYLAGQHCQQPAPSPGNTAAPGSVPAVVGSALLLLMLLVLLGLGGRRWLQKKGSCPFQSNTEATAPGFDNILFNADGVTLPASVTSDP

Target ORF information:

RefSeq Version	NM_206920.3
Organism	Homo sapiens(human)
Definition	Homo sapiens MAM domain containing 4 (MAMDC4), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_206920.3

ORF Insert Sequence:

ATGCCTCTGT CCAGCCACCT GCTGCCCGCC TTGGTCCTGT TCCTGGCAGG GTCCTCAGGC 
TGGGCCTGGG TCCCCAACCA CTGCAGGAGC CCTGGCCAGG CCGTGTGCAA CTTCGTGTGT 
GACTGCAGGG ACTGCTCAGA TGAGGCCCAG TGTGGTTACC ACGGGGCCTC GCCCACCCTG 
GGCGCCCCCT TCGCCTGTGA CTTCGAGCAG GACCCCTGCG GCTGGCGGGA CATTAGTACC 
TCAGGCTACA GCTGGCTCCG AGACAGGGCA GGGGCCGCAC TGGAGGGTCC TGGGCCTCAC 
TCAGACCACA CACTGGGCAC CGACTTGGGC TGGTACATGG CCGTTGGAAC CCACCGAGGG 
AAAGAGGCAT CCACCGCAGC CCTGCGCTCG CCAACCCTGC GAGAGGCAGC CTCCTCTTGC 
AAGCTGAGGC TCTGGTACCA CGCGGCCTCT GGAGATGTGG CTGAACTGCG GGTGGAGCTG 
ACCCATGGCG CAGAGACCCT GACCCTGTGG CAGAGCACAG GGCCCTGGGG CCCTGGCTGG 
CAGGAGTTGG CAGTGACCAC AGGCCGCATC CGGGGTGACT TCCGAGTGAC CTTCTCTGCC 
ACCCGAAATG CCACCCACAG GGGCGCTGTG GCTCTAGATG ACCTAGAGTT CTGGGACTGT 
GGTCTGCCCA CCCCCCAGGC CAACTGTCCC CCGGGACACC ACCACTGCCA GAACAAGGTC 
TGCGTGGAGC CCCAGCAGCT GTGCGACGGG GAAGACAACT GCGGGGACCT GTCTGATGAG 
AACCCACTCA CCTGTGGCCG CCACATAGCC ACCGACTTTG AGACAGGCCT GGGCCCATGG 
AACCGCTCGG AAGGCTGGTC CCGGAACCAC CGCGCTGGTG GTCCTGAGCG CCCCTCCTGG 
CCACGCCGTG ACCACAGCCG GAACAGTGCA CAGGGCTCCT TCCTGGTCTC CGTGGCCGAG 
CCTGGCACCC CTGCTATACT CTCCAGCCCC GAATTCCAAG CCTCAGGCAC CTCCAACTGC 
TCGCTGGTCT TCTATCAGTA CCTGAGTGGG TCTGAGGCTG GCTGCCTCCA GCTGTTCCTG 
CAGACTCTGG GGCCCGGCGC CCCCCGGGCC CCCGTCCTGC TGCGGAGGCG CCGAGGGGAG 
CTGGGGACCG CCTGGGTCCG AGACCGTGTT GACATCCAGA GCGCCTACCC CTTCCAGATC 
CTCCTGGCCG GGCAGACAGG CCCGGGGGGC GTCGTGGGTC TGGACGACCT CATCCTGTCT 
GACCACTGCA GACCAGTCTC GGAGGTGTCC ACCCTGCAGC CGCTGCCTCC TGGGCCCCGG 
GCCCCAGCCC CCCAGCCCCT GCCGCCCAGC TCGCGGCTCC AGGATTCCTG CAAGCAGGGG 
CATCTTGCCT GCGGGGACCT GTGTGTGCCC CCGGAACAAC TGTGTGACTT CGAGGAGCAG 
TGCGCAGGGG GCGAGGACGA GCAGGCCTGT GGCACCACAG ACTTTGAGTC CCCCGAGGCT 
GGGGGCTGGG AGGACGCCAG CGTGGGGCGG CTGCAGTGGC GGCGTGTCTC AGCCCAGGAG 
AGCCAGGGGT CCAGTGCAGC TGCTGCTGGG CACTTCCTGT CTCTGCAGCG GGCCTGGGGG 
CAGCTAGGCG CTGAGGCCCG GGTCCTCACA CCCCTCCTTG GCCCTTCTGG CCCCAGCTGT 
GAACTCCACC TGGCTTATTA TTTACAGAGC CAGCCCCGAG AGGTCTCCTG TAACTTTGAG 
CGGGACACAT GCAGCTGGTA CCCAGGCCAC CTCTCAGACA CACACTGGCG CTGGGTGGAG 
AGCCGCGGCC CTGACCACGA CCACACCACA GGCCAAGGCC ACTTTGTGCT CCTGGACCCC 
ACAGACCCCC TGGCCTGGGG CCACAGTGCC CACCTGCTCT CCAGGCCCCA GGTGCCAGCA 
GCACCCACGG AGTGTCTCAG CTTCTGGTAC CACCTCCATG GGCCCCAGAT TGGGACTCTG 
CGCCTAGCCA TGAGACGGGA AGGGGAGGAG ACACACCTGT GGTCGCGGTC AGGCACCCAG 
GGCAACCGCT GGCACGAGGC CTGGGCCACC CTTTCCCACC AGCCTGGCTC CCATGCCCAG 
TACCAGCTGC TGTTCGAGGG CCTCCGGGAC GGATACCACG GCACCATGGC GCTGGACGAT 
GTGGCCGTGC GGCCGGGCCC CTGCTGGGCC CCTAATTACT GCTCCTTTGA GGACTCAGAC 
TGCGGCTTCT CCCCTGGAGG CCAAGGTCTC TGGAGGCGGC AGGCCAATGC CTCGGGCCAT 
GCTGCCTGGG GCCCCCCAAC AGACCATACC ACTGAGACAG CCCAAGGGCA CTACATGGTG 
GTGGACACAA GCCCAGACGC ACTACCCCGG GGCCAGACGG CCTCCCTGAC CTCCAAGGAG 
CACAGGCCCC TGGCCCAGCC TGCTTGTCTG ACCTTCTGGT ACCACGGGAG CCTCCGCAGC 
CCAGGCACCC TGCGGGTCTA CCTGGAGGAG CGCGGGAGGC ACCAGGTGCT CAGCCTCAGT 
GCCCACGGCG GGCTTGCCTG GCGCCTGGGC AGCATGGACG TGCAGGCCGA GCGAGCCTGG 
AGGGTGGTGT TTGAGGCAGT GGCCGCAGGC GTGGCACACT CCTACGTGGC TCTGGATGAT 
CTGCTCCTCC AGGACGGGCC CTGCCCTCAG CCAGGTTCCT GTGATTTTGA GTCTGGCCTG 
TGTGGCTGGA GCCACCTGGC CTGGCCCGGC CTGGGCGGAT ACAGCTGGGA CTGGGGCGGG 
GGAGCCACCC CCTCTCGTTA CCCCCAGCCC CCTGTGGACC ACACCCTGGG CACAGAGGCA 
GGCCACTTTG CCTTCTTTGA AACTGGCGTG CTGGGCCCCG GGGGCCGGGC CGCCTGGCTG 
CGCAGCGAGC CTCTGCCGGC CACCCCAGCC TCCTGCCTCC GCTTCTGGTA CCACATGGGT 
TTTCCTGAGC ACTTCTACAA GGGGGAGCTG AAGGTACTGC TGCACAGTGC TCAGGGCCAG 
CTGGCTGTGT GGGGCGCAGG CGGGCATCGG CGGCACCAGT GGCTGGAGGC CCAGGTGGAG 
GTAGCCAGTG CCAAGGAGTT CCAGATCGTG TTTGAAGCCA CTCTGGGCGG CCAGCCAGCC 
CTGGGGCCCA TTGCCCTGGA TGACGTGGAG TATCTGGCTG GGCAGCATTG CCAGCAGCCT 
GCCCCCAGCC CGGGGAACAC AGCCGCACCC GGGTCTGTGC CAGCTGTGGT TGGCAGTGCC 
CTCCTATTGC TCATGCTCCT GGTGCTGCTG GGACTTGGGG GACGGCGCTG GCTGCAGAAG 
AAGGGGAGCT GCCCCTTCCA GAGCAACACA GAGGCCACAG CCCCTGGCTT TGACAACATC 
CTTTTCAATG CGGATGGTGT CACCCTCCCG GCATCTGTCA CCAGTGATCC GTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

MAMDC4 ( NM_206920.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_996803.2 Homo sapiens MAM domain containing 4 (MAMDC4), mRNA.

Price & Availability↑

CloneID	OHu29009
Clone ID Related Accession (Same CDS sequence)	NM_206920.3 , NM_206920.2
Accession Version	NM_206920.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 3414bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-04-28
Organism	Homo sapiens(human)
Product	apical endosomal glycoprotein precursor
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AY358419.1, AL355987.31, BF339007.1 and BQ270782.1. On Dec 8, 2006 this sequence version replaced NM_206920.1. ##Evidence-Data-START## Transcript exon combination :: AY358419.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968968, SAMEA2145893 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGCCTCTGT CCAGCCACCT GCTGCCCGCC TTGGTCCTGT TCCTGGCAGG GTCCTCAGGC 
TGGGCCTGGG TCCCCAACCA CTGCAGGAGC CCTGGCCAGG CCGTGTGCAA CTTCGTGTGT 
GACTGCAGGG ACTGCTCAGA TGAGGCCCAG TGTGGTTACC ACGGGGCCTC GCCCACCCTG 
GGCGCCCCCT TCGCCTGTGA CTTCGAGCAG GACCCCTGCG GCTGGCGGGA CATTAGTACC 
TCAGGCTACA GCTGGCTCCG AGACAGGGCA GGGGCCGCAC TGGAGGGTCC TGGGCCTCAC 
TCAGACCACA CACTGGGCAC CGACTTGGGC TGGTACATGG CCGTTGGAAC CCACCGAGGG 
AAAGAGGCAT CCACCGCAGC CCTGCGCTCG CCAACCCTGC GAGAGGCAGC CTCCTCTTGC 
AAGCTGAGGC TCTGGTACCA CGCGGCCTCT GGAGATGTGG CTGAACTGCG GGTGGAGCTG 
ACCCATGGCG CAGAGACCCT GACCCTGTGG CAGAGCACAG GGCCCTGGGG CCCTGGCTGG 
CAGGAGTTGG CAGTGACCAC AGGCCGCATC CGGGGTGACT TCCGAGTGAC CTTCTCTGCC 
ACCCGAAATG CCACCCACAG GGGCGCTGTG GCTCTAGATG ACCTAGAGTT CTGGGACTGT 
GGTCTGCCCA CCCCCCAGGC CAACTGTCCC CCGGGACACC ACCACTGCCA GAACAAGGTC 
TGCGTGGAGC CCCAGCAGCT GTGCGACGGG GAAGACAACT GCGGGGACCT GTCTGATGAG 
AACCCACTCA CCTGTGGCCG CCACATAGCC ACCGACTTTG AGACAGGCCT GGGCCCATGG 
AACCGCTCGG AAGGCTGGTC CCGGAACCAC CGCGCTGGTG GTCCTGAGCG CCCCTCCTGG 
CCACGCCGTG ACCACAGCCG GAACAGTGCA CAGGGCTCCT TCCTGGTCTC CGTGGCCGAG 
CCTGGCACCC CTGCTATACT CTCCAGCCCC GAATTCCAAG CCTCAGGCAC CTCCAACTGC 
TCGCTGGTCT TCTATCAGTA CCTGAGTGGG TCTGAGGCTG GCTGCCTCCA GCTGTTCCTG 
CAGACTCTGG GGCCCGGCGC CCCCCGGGCC CCCGTCCTGC TGCGGAGGCG CCGAGGGGAG 
CTGGGGACCG CCTGGGTCCG AGACCGTGTT GACATCCAGA GCGCCTACCC CTTCCAGATC 
CTCCTGGCCG GGCAGACAGG CCCGGGGGGC GTCGTGGGTC TGGACGACCT CATCCTGTCT 
GACCACTGCA GACCAGTCTC GGAGGTGTCC ACCCTGCAGC CGCTGCCTCC TGGGCCCCGG 
GCCCCAGCCC CCCAGCCCCT GCCGCCCAGC TCGCGGCTCC AGGATTCCTG CAAGCAGGGG 
CATCTTGCCT GCGGGGACCT GTGTGTGCCC CCGGAACAAC TGTGTGACTT CGAGGAGCAG 
TGCGCAGGGG GCGAGGACGA GCAGGCCTGT GGCACCACAG ACTTTGAGTC CCCCGAGGCT 
GGGGGCTGGG AGGACGCCAG CGTGGGGCGG CTGCAGTGGC GGCGTGTCTC AGCCCAGGAG 
AGCCAGGGGT CCAGTGCAGC TGCTGCTGGG CACTTCCTGT CTCTGCAGCG GGCCTGGGGG 
CAGCTAGGCG CTGAGGCCCG GGTCCTCACA CCCCTCCTTG GCCCTTCTGG CCCCAGCTGT 
GAACTCCACC TGGCTTATTA TTTACAGAGC CAGCCCCGAG AGGTCTCCTG TAACTTTGAG 
CGGGACACAT GCAGCTGGTA CCCAGGCCAC CTCTCAGACA CACACTGGCG CTGGGTGGAG 
AGCCGCGGCC CTGACCACGA CCACACCACA GGCCAAGGCC ACTTTGTGCT CCTGGACCCC 
ACAGACCCCC TGGCCTGGGG CCACAGTGCC CACCTGCTCT CCAGGCCCCA GGTGCCAGCA 
GCACCCACGG AGTGTCTCAG CTTCTGGTAC CACCTCCATG GGCCCCAGAT TGGGACTCTG 
CGCCTAGCCA TGAGACGGGA AGGGGAGGAG ACACACCTGT GGTCGCGGTC AGGCACCCAG 
GGCAACCGCT GGCACGAGGC CTGGGCCACC CTTTCCCACC AGCCTGGCTC CCATGCCCAG 
TACCAGCTGC TGTTCGAGGG CCTCCGGGAC GGATACCACG GCACCATGGC GCTGGACGAT 
GTGGCCGTGC GGCCGGGCCC CTGCTGGGCC CCTAATTACT GCTCCTTTGA GGACTCAGAC 
TGCGGCTTCT CCCCTGGAGG CCAAGGTCTC TGGAGGCGGC AGGCCAATGC CTCGGGCCAT 
GCTGCCTGGG GCCCCCCAAC AGACCATACC ACTGAGACAG CCCAAGGGCA CTACATGGTG 
GTGGACACAA GCCCAGACGC ACTACCCCGG GGCCAGACGG CCTCCCTGAC CTCCAAGGAG 
CACAGGCCCC TGGCCCAGCC TGCTTGTCTG ACCTTCTGGT ACCACGGGAG CCTCCGCAGC 
CCAGGCACCC TGCGGGTCTA CCTGGAGGAG CGCGGGAGGC ACCAGGTGCT CAGCCTCAGT 
GCCCACGGCG GGCTTGCCTG GCGCCTGGGC AGCATGGACG TGCAGGCCGA GCGAGCCTGG 
AGGGTGGTGT TTGAGGCAGT GGCCGCAGGC GTGGCACACT CCTACGTGGC TCTGGATGAT 
CTGCTCCTCC AGGACGGGCC CTGCCCTCAG CCAGGTTCCT GTGATTTTGA GTCTGGCCTG 
TGTGGCTGGA GCCACCTGGC CTGGCCCGGC CTGGGCGGAT ACAGCTGGGA CTGGGGCGGG 
GGAGCCACCC CCTCTCGTTA CCCCCAGCCC CCTGTGGACC ACACCCTGGG CACAGAGGCA 
GGCCACTTTG CCTTCTTTGA AACTGGCGTG CTGGGCCCCG GGGGCCGGGC CGCCTGGCTG 
CGCAGCGAGC CTCTGCCGGC CACCCCAGCC TCCTGCCTCC GCTTCTGGTA CCACATGGGT 
TTTCCTGAGC ACTTCTACAA GGGGGAGCTG AAGGTACTGC TGCACAGTGC TCAGGGCCAG 
CTGGCTGTGT GGGGCGCAGG CGGGCATCGG CGGCACCAGT GGCTGGAGGC CCAGGTGGAG 
GTAGCCAGTG CCAAGGAGTT CCAGATCGTG TTTGAAGCCA CTCTGGGCGG CCAGCCAGCC 
CTGGGGCCCA TTGCCCTGGA TGACGTGGAG TATCTGGCTG GGCAGCATTG CCAGCAGCCT 
GCCCCCAGCC CGGGGAACAC AGCCGCACCC GGGTCTGTGC CAGCTGTGGT TGGCAGTGCC 
CTCCTATTGC TCATGCTCCT GGTGCTGCTG GGACTTGGGG GACGGCGCTG GCTGCAGAAG 
AAGGGGAGCT GCCCCTTCCA GAGCAACACA GAGGCCACAG CCCCTGGCTT TGACAACATC 
CTTTTCAATG CGGATGGTGT CACCCTCCCG GCATCTGTCA CCAGTGATCC GTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_996803.2
CDS	51..3464
Translation	MPLSSHLLPALVLFLAGSSGWAWVPNHCRSPGQAVCNFVCDCRDCSDEAQCGYHGASPTLGAPFACDFEQDPCGWRDISTSGYSWLRDRAGAALEGPGPHSDHTLGTDLGWYMAVGTHRGKEASTAALRSPTLREAASSCKLRLWYHAASGDVAELRVELTHGAETLTLWQSTGPWGPGWQELAVTTGRIRGDFRVTFSATRNATHRGAVALDDLEFWDCGLPTPQANCPPGHHHCQNKVCVEPQQLCDGEDNCGDLSDENPLTCGRHIATDFETGLGPWNRSEGWSRNHRAGGPERPSWPRRDHSRNSAQGSFLVSVAEPGTPAILSSPEFQASGTSNCSLVFYQYLSGSEAGCLQLFLQTLGPGAPRAPVLLRRRRGELGTAWVRDRVDIQSAYPFQILLAGQTGPGGVVGLDDLILSDHCRPVSEVSTLQPLPPGPRAPAPQPLPPSSRLQDSCKQGHLACGDLCVPPEQLCDFEEQCAGGEDEQACGTTDFESPEAGGWEDASVGRLQWRRVSAQESQGSSAAAAGHFLSLQRAWGQLGAEARVLTPLLGPSGPSCELHLAYYLQSQPREVSCNFERDTCSWYPGHLSDTHWRWVESRGPDHDHTTGQGHFVLLDPTDPLAWGHSAHLLSRPQVPAAPTECLSFWYHLHGPQIGTLRLAMRREGEETHLWSRSGTQGNRWHEAWATLSHQPGSHAQYQLLFEGLRDGYHGTMALDDVAVRPGPCWAPNYCSFEDSDCGFSPGGQGLWRRQANASGHAAWGPPTDHTTETAQGHYMVVDTSPDALPRGQTASLTSKEHRPLAQPACLTFWYHGSLRSPGTLRVYLEERGRHQVLSLSAHGGLAWRLGSMDVQAERAWRVVFEAVAAGVAHSYVALDDLLLQDGPCPQPGSCDFESGLCGWSHLAWPGLGGYSWDWGGGATPSRYPQPPVDHTLGTEAGHFAFFETGVLGPGGRAAWLRSEPLPATPASCLRFWYHMGFPEHFYKGELKVLLHSAQGQLAVWGAGGHRRHQWLEAQVEVASAKEFQIVFEATLGGQPALGPIALDDVEYLAGQHCQQPAPSPGNTAAPGSVPAVVGSALLLLMLLVLLGLGGRRWLQKKGSCPFQSNTEATAPGFDNILFNADGVTLPASVTSDP

Target ORF information:

RefSeq Version	NM_206920.2
Organism	Homo sapiens(human)
Definition	Homo sapiens MAM domain containing 4 (MAMDC4), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_206920.2

ORF Insert Sequence:

ATGCCTCTGT CCAGCCACCT GCTGCCCGCC TTGGTCCTGT TCCTGGCAGG GTCCTCAGGC 
TGGGCCTGGG TCCCCAACCA CTGCAGGAGC CCTGGCCAGG CCGTGTGCAA CTTCGTGTGT 
GACTGCAGGG ACTGCTCAGA TGAGGCCCAG TGTGGTTACC ACGGGGCCTC GCCCACCCTG 
GGCGCCCCCT TCGCCTGTGA CTTCGAGCAG GACCCCTGCG GCTGGCGGGA CATTAGTACC 
TCAGGCTACA GCTGGCTCCG AGACAGGGCA GGGGCCGCAC TGGAGGGTCC TGGGCCTCAC 
TCAGACCACA CACTGGGCAC CGACTTGGGC TGGTACATGG CCGTTGGAAC CCACCGAGGG 
AAAGAGGCAT CCACCGCAGC CCTGCGCTCG CCAACCCTGC GAGAGGCAGC CTCCTCTTGC 
AAGCTGAGGC TCTGGTACCA CGCGGCCTCT GGAGATGTGG CTGAACTGCG GGTGGAGCTG 
ACCCATGGCG CAGAGACCCT GACCCTGTGG CAGAGCACAG GGCCCTGGGG CCCTGGCTGG 
CAGGAGTTGG CAGTGACCAC AGGCCGCATC CGGGGTGACT TCCGAGTGAC CTTCTCTGCC 
ACCCGAAATG CCACCCACAG GGGCGCTGTG GCTCTAGATG ACCTAGAGTT CTGGGACTGT 
GGTCTGCCCA CCCCCCAGGC CAACTGTCCC CCGGGACACC ACCACTGCCA GAACAAGGTC 
TGCGTGGAGC CCCAGCAGCT GTGCGACGGG GAAGACAACT GCGGGGACCT GTCTGATGAG 
AACCCACTCA CCTGTGGCCG CCACATAGCC ACCGACTTTG AGACAGGCCT GGGCCCATGG 
AACCGCTCGG AAGGCTGGTC CCGGAACCAC CGCGCTGGTG GTCCTGAGCG CCCCTCCTGG 
CCACGCCGTG ACCACAGCCG GAACAGTGCA CAGGGCTCCT TCCTGGTCTC CGTGGCCGAG 
CCTGGCACCC CTGCTATACT CTCCAGCCCC GAATTCCAAG CCTCAGGCAC CTCCAACTGC 
TCGCTGGTCT TCTATCAGTA CCTGAGTGGG TCTGAGGCTG GCTGCCTCCA GCTGTTCCTG 
CAGACTCTGG GGCCCGGCGC CCCCCGGGCC CCCGTCCTGC TGCGGAGGCG CCGAGGGGAG 
CTGGGGACCG CCTGGGTCCG AGACCGTGTT GACATCCAGA GCGCCTACCC CTTCCAGATC 
CTCCTGGCCG GGCAGACAGG CCCGGGGGGC GTCGTGGGTC TGGACGACCT CATCCTGTCT 
GACCACTGCA GACCAGTCTC GGAGGTGTCC ACCCTGCAGC CGCTGCCTCC TGGGCCCCGG 
GCCCCAGCCC CCCAGCCCCT GCCGCCCAGC TCGCGGCTCC AGGATTCCTG CAAGCAGGGG 
CATCTTGCCT GCGGGGACCT GTGTGTGCCC CCGGAACAAC TGTGTGACTT CGAGGAGCAG 
TGCGCAGGGG GCGAGGACGA GCAGGCCTGT GGCACCACAG ACTTTGAGTC CCCCGAGGCT 
GGGGGCTGGG AGGACGCCAG CGTGGGGCGG CTGCAGTGGC GGCGTGTCTC AGCCCAGGAG 
AGCCAGGGGT CCAGTGCAGC TGCTGCTGGG CACTTCCTGT CTCTGCAGCG GGCCTGGGGG 
CAGCTAGGCG CTGAGGCCCG GGTCCTCACA CCCCTCCTTG GCCCTTCTGG CCCCAGCTGT 
GAACTCCACC TGGCTTATTA TTTACAGAGC CAGCCCCGAG AGGTCTCCTG TAACTTTGAG 
CGGGACACAT GCAGCTGGTA CCCAGGCCAC CTCTCAGACA CACACTGGCG CTGGGTGGAG 
AGCCGCGGCC CTGACCACGA CCACACCACA GGCCAAGGCC ACTTTGTGCT CCTGGACCCC 
ACAGACCCCC TGGCCTGGGG CCACAGTGCC CACCTGCTCT CCAGGCCCCA GGTGCCAGCA 
GCACCCACGG AGTGTCTCAG CTTCTGGTAC CACCTCCATG GGCCCCAGAT TGGGACTCTG 
CGCCTAGCCA TGAGACGGGA AGGGGAGGAG ACACACCTGT GGTCGCGGTC AGGCACCCAG 
GGCAACCGCT GGCACGAGGC CTGGGCCACC CTTTCCCACC AGCCTGGCTC CCATGCCCAG 
TACCAGCTGC TGTTCGAGGG CCTCCGGGAC GGATACCACG GCACCATGGC GCTGGACGAT 
GTGGCCGTGC GGCCGGGCCC CTGCTGGGCC CCTAATTACT GCTCCTTTGA GGACTCAGAC 
TGCGGCTTCT CCCCTGGAGG CCAAGGTCTC TGGAGGCGGC AGGCCAATGC CTCGGGCCAT 
GCTGCCTGGG GCCCCCCAAC AGACCATACC ACTGAGACAG CCCAAGGGCA CTACATGGTG 
GTGGACACAA GCCCAGACGC ACTACCCCGG GGCCAGACGG CCTCCCTGAC CTCCAAGGAG 
CACAGGCCCC TGGCCCAGCC TGCTTGTCTG ACCTTCTGGT ACCACGGGAG CCTCCGCAGC 
CCAGGCACCC TGCGGGTCTA CCTGGAGGAG CGCGGGAGGC ACCAGGTGCT CAGCCTCAGT 
GCCCACGGCG GGCTTGCCTG GCGCCTGGGC AGCATGGACG TGCAGGCCGA GCGAGCCTGG 
AGGGTGGTGT TTGAGGCAGT GGCCGCAGGC GTGGCACACT CCTACGTGGC TCTGGATGAT 
CTGCTCCTCC AGGACGGGCC CTGCCCTCAG CCAGGTTCCT GTGATTTTGA GTCTGGCCTG 
TGTGGCTGGA GCCACCTGGC CTGGCCCGGC CTGGGCGGAT ACAGCTGGGA CTGGGGCGGG 
GGAGCCACCC CCTCTCGTTA CCCCCAGCCC CCTGTGGACC ACACCCTGGG CACAGAGGCA 
GGCCACTTTG CCTTCTTTGA AACTGGCGTG CTGGGCCCCG GGGGCCGGGC CGCCTGGCTG 
CGCAGCGAGC CTCTGCCGGC CACCCCAGCC TCCTGCCTCC GCTTCTGGTA CCACATGGGT 
TTTCCTGAGC ACTTCTACAA GGGGGAGCTG AAGGTACTGC TGCACAGTGC TCAGGGCCAG 
CTGGCTGTGT GGGGCGCAGG CGGGCATCGG CGGCACCAGT GGCTGGAGGC CCAGGTGGAG 
GTAGCCAGTG CCAAGGAGTT CCAGATCGTG TTTGAAGCCA CTCTGGGCGG CCAGCCAGCC 
CTGGGGCCCA TTGCCCTGGA TGACGTGGAG TATCTGGCTG GGCAGCATTG CCAGCAGCCT 
GCCCCCAGCC CGGGGAACAC AGCCGCACCC GGGTCTGTGC CAGCTGTGGT TGGCAGTGCC 
CTCCTATTGC TCATGCTCCT GGTGCTGCTG GGACTTGGGG GACGGCGCTG GCTGCAGAAG 
AAGGGGAGCT GCCCCTTCCA GAGCAACACA GAGGCCACAG CCCCTGGCTT TGACAACATC 
CTTTTCAATG CGGATGGTGT CACCCTCCCG GCATCTGTCA CCAGTGATCC GTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Private rare deletions in SEC16A and MAMDC4 may represent novel pathogenic variants in familial axial spondyloarthritis.
Annals of the rheumatic diseases75(4)772-9(2016 Apr)
O'Rielly DD,Uddin M,Codner D,Hayley M,Zhou J,Pena-Castillo L,Mostafa AA,Hasan SM,Liu W,Haroon N,Inman R,Rahman P

The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment.
Genome research13(10)2265-70(2003 Oct)
Clark HF,Gurney AL,Abaya E,Baker K,Baldwin D,Brush J,Chen J,Chow B,Chui C,Crowley C,Currell B,Deuel B,Dowd P,Eaton D,Foster J,Grimaldi C,Gu Q,Hass PE,Heldens S,Huang A,Kim HS,Klimowski L,Jin Y,Johnson S,Lee J,Lewis L,Liao D,Mark M,Robbie E,Sanchez C,Schoenfeld J,Seshagiri S,Simmons L,Singh J,Smith V,Stinson J,Vagts A,Vandlen R,Watanabe C,Wieand D,Woods K,Xie MH,Yansura D,Yi S,Yu G,Yuan J,Zhang M,Zhang Z,Goddard A,Wood WI,Godowski P,Gray A

Molecular characterization of an apical early endosomal glycoprotein from developing rat intestinal epithelial cells.
The Journal of biological chemistry270(4)1583-8(1995 Jan)
Speelman BA,Allen K,Grounds TL,Neutra MR,Kirchhausen T,Wilson JM

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MAMDC4 cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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