MARVELD2 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	MARVELD2
Entrez Gene ID	153562
Full Name	MARVEL domain containing 2
Synonyms	DFNB49,MARVD2,MRVLDC2,Tric
General protein information	Preferred Names MARVEL domain containing 2 Names MARVEL domain-containing protein 2 MARVEL (membrane-associating) domain containing 2 tricellulin
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 5 Map Location: 5q13.2
Summary	The protein encoded by this gene is a membrane protein found at the tight junctions between epithelial cells. The encoded protein helps establish epithelial barriers such as those in the organ of Corti, where these barriers are required for normal hearing. Defects in this gene are a cause of deafness autosomal recessive type 49 (DFNB49). Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2011].
Disorder MIM:	610572
Disorder Html:	Deafness, autosomal recessive 49, 610153 (3)

mRNA and Protein(s)

mRNA	Protein	Name
XM_005248447.4	XP_005248504.1	MARVEL domain-containing protein 2 isoform X2
NM_001038603.2	NP_001033692.2	MARVEL domain-containing protein 2 isoform 1
NM_001244734.1	NP_001231663.1	MARVEL domain-containing protein 2 isoform 2
XM_005248445.4	XP_005248502.1	MARVEL domain-containing protein 2 isoform X1
XM_005248446.4	XP_005248503.1	MARVEL domain-containing protein 2 isoform X1
NM_001038603.3	NP_001033692.2	MARVEL domain-containing protein 2 isoform 1
NM_001244734.2	NP_001231663.1	MARVEL domain-containing protein 2 isoform 2

Pathways from BioSystems

Homologies

Bos taurus (cattle)	MARVELD2	XP_002696327.1
Mus musculus (house mouse)	Marveld2	NP_001033691.1
Danio rerio (zebrafish)	marveld2a	XP_687068.1
Xenopus tropicalis (tropical clawed frog)	marveld2	NP_001017292.1
Homo sapiens (human)	MARVELD2	NP_001033692.2
Rattus norvegicus (Norway rat)	Marveld2	NP_001102406.1
	MARVELD2	XP_001094419.1
Canis lupus familiaris (dog)	MARVELD2	XP_005617521.1
Pan troglodytes (chimpanzee)	MARVELD2	XP_517724.2
Gallus gallus (chicken)	MARVELD2	XP_424965.4
Danio rerio (zebrafish)	marveld2b	NP_001119878.1

Gene Ontology
Bibliography

Related articles in PubMed

Crystal structure of the tricellulin C-terminal coiled-coil domain reveals a unique mode of dimerization.
Schuetz A, Radusheva V, Krug SM, Heinemann U
Annals of the New York Academy of Sciences1405(1)147-159(2017 Oct)

Contribution of the tricellular tight junction to paracellular permeability in leaky and tight epithelia.
Krug SM
Annals of the New York Academy of Sciences1397(1)219-230(2017 Jun)

Tricellulin is regulated via interleukin-13-receptor ?2, affects macromolecule uptake, and is decreased in ulcerative colitis.
Krug SM, Bojarski C, Fromm A, Lee IM, Dames P, Richter JF, Turner JR, Fromm M, Schulzke JD
Mucosal immunology(2017 Jun)

Tricellulin is a target of the ubiquitin ligase Itch.
Jennek S, Mittag S, Reiche J, Westphal JK, Seelk S, D?rfel MJ, Pfirrmann T, Friedrich K, Sch?tz A, Heinemann U, Huber O
Annals of the New York Academy of Sciences1397(1)157-168(2017 Jun)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Tricellulin-dependent macromolecule passage was comparably regulated in leaky and tight epithelia, but relative and absolute ion permeabilities of the tricellular tight junction (tTJ) were different.
Title: Contribution of the tricellular tight junction to paracellular permeability in leaky and tight epithelia.

Data show that the E3 ubiquitin ligase Itch forms a complex with tricellulin and thereby enhances its ubiquitination.
Title: Tricellulin is a target of the ubiquitin ligase Itch.

we demonstrated that PLG functions as a molecular bridge between tricellulin and streptococcal surface enolase (SEN). The wild type strain efficiently translocated across the epithelial monolayer, accompanied by cleavage of transmembrane junctional proteins.
Title: Group A Streptococcus exploits human plasminogen for bacterial translocation across epithelial barrier via tricellular tight junctions.

MARVELD2 variants are responsible for about 1.5 % (95 % CI 0.8-2.6) of non-syndromic hearing loss in our cohort of 800 Pakistani families. The c.1331+2T>C allele is recurrent.
Title: Molecular genetics of MARVELD2 and clinical phenotype in Pakistani and Slovak families segregating DFNB49 hearing loss.

The expressions of MARVELD2, CLDN1 and CLDN3 mRNA were significantly lower in cholesteatoma tissue and may be involved in epithelium permeability.
Title: Increased permeability of the epithelium of middle ear cholesteatoma.

The following MARVELD2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the MARVELD2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu26081	NM_001038603.3 Latest version!	Homo sapiens MARVEL domain containing 2 (MARVELD2), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$219.50-$307.30 $439.00
OHu10219	NM_001244734.2 Latest version!	Homo sapiens MARVEL domain containing 2 (MARVELD2), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$307.30 $439.00
OHu10219	XM_005248447.4 Latest version!	Homo sapiens MARVEL domain containing 2 (MARVELD2), transcript variant X3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$307.30 $439.00
OHu26081	XM_005248445.4 Latest version!	Homo sapiens MARVEL domain containing 2 (MARVELD2), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$265.30 $379.00
OHu26081	XM_005248446.4 Latest version!	Homo sapiens MARVEL domain containing 2 (MARVELD2), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$265.30 $379.00
View Old Accession Versions >>
OHu26081	NM_001038603.2	Homo sapiens MARVEL domain containing 2 (MARVELD2), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$265.30 $379.00
OHu10219	NM_001244734.1	Homo sapiens MARVEL domain containing 2 (MARVELD2), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$307.30 $439.00
Hide Old Accession Versions >>

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***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

MARVELD2 ( NM_001038603.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_001033692.2 Homo sapiens MARVEL domain containing 2 (MARVELD2), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu26081
Clone ID Related Accession (Same CDS sequence)	NM_001038603.2 , XM_005248445.4 , XM_005248446.4 , NM_001038603.3
Accession Version	NM_001038603.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1677bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-08-06
Organism	Homo sapiens(human)
Product	MARVEL domain-containing protein 2 isoform 1
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BG943115.1, BC033689.1, AK292962.1 and AC145146.2. This sequence is a reference standard in the RefSeqGene project. On Nov 22, 2018 this sequence version replaced NM_001038603.2. Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1660807.143266.1, BC033689.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968540, SAMEA1968832 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000325631.10/ ENSP00000323264.5 RefSeq Select criteria :: based on conservation, longest protein ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGTCAAATG ATGGAAGATC CAGGAATCGG GACAGGCGCT ACGATGAGGT CCCAAGCGAC 
CTGCCCTATC AAGATACCAC CATAAGAACC CACCCAACTC TTCATGACAG TGAGCGGGCA 
GTGAGCGCTG ATCCCTTGCC ACCACCCCCT CTCCCATTAC AGCCACCATT CGGCCCAGAC 
TTCTACTCAA GTGACACAGA AGAACCAGCT ATAGCGCCAG ATCTCAAACC AGTAAGGCGC 
TTTGTCCCTG ACTCCTGGAA GAACTTTTTC AGAGGGAAGA AAAAGGACCC CGAATGGGAT 
AAGCCGGTGT CTGATATCAG GTACATCTCC GATGGAGTGG AGTGTTCACC ACCAGCCTCT 
CCAGCAAGAC CAAACCACCG TTCGCCCCTC AACTCCTGCA AAGATCCCTA CGGAGGGTCA 
GAAGGAACCT TTAGTTCCCG GAAAGAGGCT GACGCAGTGT TTCCCCGGGA TCCCTATGGA 
TCTCTAGACC GACACACACA AACAGTTCGA ACATACAGTG AGAAGGTGGA GGAGTATAAC 
CTGAGATACT CCTACATGAA GTCGTGGGCA GGCCTGCTGA GAATACTGGG TGTGGTGGAG 
CTGCTTTTGG GGGCCGGTGT CTTTGCTTGT GTCACAGCTT ACATTCACAA GGACAGTGAG 
TGGTACAACT TGTTTGGATA TTCACAACCG TATGGCATGG GAGGCGTTGG TGGATTGGGC 
AGTATGTATG GGGGCTATTA CTACACTGGC CCTAAGACCC CTTTTGTACT CGTGGTTGCT 
GGATTAGCTT GGATCACCAC CATTATTATT CTGGTTCTTG GCATGTCCAT GTATTACCGG 
ACCATTCTTC TGGACTCTAA TTGGTGGCCC CTAACTGAAT TTGGAATTAA CGTTGCCTTG 
TTTATTTTGT ATATGGCCGC AGCCATAGTC TATGTGAATG ATACCAACCG AGGTGGCCTC 
TGCTACTATC CGTTATTTAA TACACCAGTG AATGCAGTGT TCTGCCGGGT AGAAGGAGGA 
CAGATAGCTG CAATGATCTT CCTGTTTGTC ACCATGATAG TTTATCTCAT TAGTGCTTTG 
GTTTGCCTAA AGTTATGGAG GCATGAGGCA GCTCGGAGAC ATAGAGAATA TATGGAACAA 
CAGGAGATAA ATGAGCCATC ATTGTCATCG AAAAGGAAAA TGTGTGAAAT GGCCACCAGT 
GGTGACAGAC AAAGAGACTC AGAAGTTAAT TTCAAGGAAC TGAGAACAGC AAAAATGAAA 
CCTGAACTAC TGAGTGGACA CATCCCCCCA GGCCACATTC CTAAACCTAT CGTGATGCCC 
GACTATGTGG CAAAATACCC TGTGATTCAG ACAGATGATG AGCGAGAACG CTATAAAGCT 
GTGTTCCAAG ACCAGTTTTC AGAGTACAAA GAGCTGTCTG CAGAAGTTCA GGCTGTCCTG 
AGGAAGTTTG ATGAGCTGGA TGCAGTGATG AGCAGATTGC CACATCATTC GGAAAGCCGA 
CAGGAACATG AGAGAATTTC AAGAATCCAT GAAGAGTTTA AGAAAAAAAA GAATGATCCT 
ACATTTCTGG AAAAAAAAGA ACGCTGTGAT TACCTAAAGA ATAAACTTTC TCACATAAAG 
CAAAGAATTC AAGAATATGA TAAAGTAATG AATTGGGATG TACAAGGTTA TTCTTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001033692.2
CDS	71..1747
Translation	MSNDGRSRNRDRRYDEVPSDLPYQDTTIRTHPTLHDSERAVSADPLPPPPLPLQPPFGPDFYSSDTEEPAIAPDLKPVRRFVPDSWKNFFRGKKKDPEWDKPVSDIRYISDGVECSPPASPARPNHRSPLNSCKDPYGGSEGTFSSRKEADAVFPRDPYGSLDRHTQTVRTYSEKVEEYNLRYSYMKSWAGLLRILGVVELLLGAGVFACVTAYIHKDSEWYNLFGYSQPYGMGGVGGLGSMYGGYYYTGPKTPFVLVVAGLAWITTIIILVLGMSMYYRTILLDSNWWPLTEFGINVALFILYMAAAIVYVNDTNRGGLCYYPLFNTPVNAVFCRVEGGQIAAMIFLFVTMIVYLISALVCLKLWRHEAARRHREYMEQQEINEPSLSSKRKMCEMATSGDRQRDSEVNFKELRTAKMKPELLSGHIPPGHIPKPIVMPDYVAKYPVIQTDDERERYKAVFQDQFSEYKELSAEVQAVLRKFDELDAVMSRLPHHSESRQEHERISRIHEEFKKKKNDPTFLEKKERCDYLKNKLSHIKQRIQEYDKVMNWDVQGYS

Target ORF information:

RefSeq Version	NM_001038603.3
Organism	Homo sapiens(human)
Definition	Homo sapiens MARVEL domain containing 2 (MARVELD2), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001038603.3

ORF Insert Sequence:

ATGTCAAATG ATGGAAGATC CAGGAATCGG GACAGGCGCT ACGATGAGGT CCCAAGCGAC 
CTGCCCTATC AAGATACCAC CATAAGAACC CACCCAACTC TTCATGACAG TGAGCGGGCA 
GTGAGCGCTG ATCCCTTGCC ACCACCCCCT CTCCCATTAC AGCCACCATT CGGCCCAGAC 
TTCTACTCAA GTGACACAGA AGAACCAGCT ATAGCGCCAG ATCTCAAACC AGTAAGGCGC 
TTTGTCCCTG ACTCCTGGAA GAACTTTTTC AGAGGGAAGA AAAAGGACCC CGAATGGGAT 
AAGCCGGTGT CTGATATCAG GTACATCTCC GATGGAGTGG AGTGTTCACC ACCAGCCTCT 
CCAGCAAGAC CAAACCACCG TTCGCCCCTC AACTCCTGCA AAGATCCCTA CGGAGGGTCA 
GAAGGAACCT TTAGTTCCCG GAAAGAGGCT GACGCAGTGT TTCCCCGGGA TCCCTATGGA 
TCTCTAGACC GACACACACA AACAGTTCGA ACATACAGTG AGAAGGTGGA GGAGTATAAC 
CTGAGATACT CCTACATGAA GTCGTGGGCA GGCCTGCTGA GAATACTGGG TGTGGTGGAG 
CTGCTTTTGG GGGCCGGTGT CTTTGCTTGT GTCACAGCTT ACATTCACAA GGACAGTGAG 
TGGTACAACT TGTTTGGATA TTCACAACCG TATGGCATGG GAGGCGTTGG TGGATTGGGC 
AGTATGTATG GGGGCTATTA CTACACTGGC CCTAAGACCC CTTTTGTACT CGTGGTTGCT 
GGATTAGCTT GGATCACCAC CATTATTATT CTGGTTCTTG GCATGTCCAT GTATTACCGG 
ACCATTCTTC TGGACTCTAA TTGGTGGCCC CTAACTGAAT TTGGAATTAA CGTTGCCTTG 
TTTATTTTGT ATATGGCCGC AGCCATAGTC TATGTGAATG ATACCAACCG AGGTGGCCTC 
TGCTACTATC CGTTATTTAA TACACCAGTG AATGCAGTGT TCTGCCGGGT AGAAGGAGGA 
CAGATAGCTG CAATGATCTT CCTGTTTGTC ACCATGATAG TTTATCTCAT TAGTGCTTTG 
GTTTGCCTAA AGTTATGGAG GCATGAGGCA GCTCGGAGAC ATAGAGAATA TATGGAACAA 
CAGGAGATAA ATGAGCCATC ATTGTCATCG AAAAGGAAAA TGTGTGAAAT GGCCACCAGT 
GGTGACAGAC AAAGAGACTC AGAAGTTAAT TTCAAGGAAC TGAGAACAGC AAAAATGAAA 
CCTGAACTAC TGAGTGGACA CATCCCCCCA GGCCACATTC CTAAACCTAT CGTGATGCCC 
GACTATGTGG CAAAATACCC TGTGATTCAG ACAGATGATG AGCGAGAACG CTATAAAGCT 
GTGTTCCAAG ACCAGTTTTC AGAGTACAAA GAGCTGTCTG CAGAAGTTCA GGCTGTCCTG 
AGGAAGTTTG ATGAGCTGGA TGCAGTGATG AGCAGATTGC CACATCATTC GGAAAGCCGA 
CAGGAACATG AGAGAATTTC AAGAATCCAT GAAGAGTTTA AGAAAAAAAA GAATGATCCT 
ACATTTCTGG AAAAAAAAGA ACGCTGTGAT TACCTAAAGA ATAAACTTTC TCACATAAAG 
CAAAGAATTC AAGAATATGA TAAAGTAATG AATTGGGATG TACAAGGTTA TTCTTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

MARVELD2 ( NM_001244734.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001231663.1 Homo sapiens MARVEL domain containing 2 (MARVELD2), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu10219
Clone ID Related Accession (Same CDS sequence)	XM_005248447.4 , NM_001244734.1 , NM_001244734.2
Accession Version	NM_001244734.1	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1641bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-03-03
Organism	Homo sapiens(human)
Product	MARVEL domain-containing protein 2 isoform 2
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BG943115.1, AC145146.2, DQ682657.1 and BC033689.1. Transcript Variant: This variant (2) lacks an alternate in-frame exon compared to variant 1. The resulting isoform (2) has the same N- and C-termini but is shorter compared to isoform 1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: DQ682657.1, SRR1803613.176169.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2142348, SAMEA2142363 [ECO:0000348] ##Evidence-Data-END##

ATGTCAAATG ATGGAAGATC CAGGAATCGG GACAGGCGCT ACGATGAGGT CCCAAGCGAC 
CTGCCCTATC AAGATACCAC CATAAGAACC CACCCAACTC TTCATGACAG TGAGCGGGCA 
GTGAGCGCTG ATCCCTTGCC ACCACCCCCT CTCCCATTAC AGCCACCATT CGGCCCAGAC 
TTCTACTCAA GTGACACAGA AGAACCAGCT ATAGCGCCAG ATCTCAAACC AGTAAGGCGC 
TTTGTCCCTG ACTCCTGGAA GAACTTTTTC AGAGGGAAGA AAAAGGACCC CGAATGGGAT 
AAGCCGGTGT CTGATATCAG GTACATCTCC GATGGAGTGG AGTGTTCACC ACCAGCCTCT 
CCAGCAAGAC CAAACCACCG TTCGCCCCTC AACTCCTGCA AAGATCCCTA CGGAGGGTCA 
GAAGGAACCT TTAGTTCCCG GAAAGAGGCT GACGCAGTGT TTCCCCGGGA TCCCTATGGA 
TCTCTAGACC GACACACACA AACAGTTCGA ACATACAGTG AGAAGGTGGA GGAGTATAAC 
CTGAGATACT CCTACATGAA GTCGTGGGCA GGCCTGCTGA GAATACTGGG TGTGGTGGAG 
CTGCTTTTGG GGGCCGGTGT CTTTGCTTGT GTCACAGCTT ACATTCACAA GGACAGTGAG 
TGGTACAACT TGTTTGGATA TTCACAACCG TATGGCATGG GAGGCGTTGG TGGATTGGGC 
AGTATGTATG GGGGCTATTA CTACACTGGC CCTAAGACCC CTTTTGTACT CGTGGTTGCT 
GGATTAGCTT GGATCACCAC CATTATTATT CTGGTTCTTG GCATGTCCAT GTATTACCGG 
ACCATTCTTC TGGACTCTAA TTGGTGGCCC CTAACTGAAT TTGGAATTAA CGTTGCCTTG 
TTTATTTTGT ATATGGCCGC AGCCATAGTC TATGTGAATG ATACCAACCG AGGTGGCCTC 
TGCTACTATC CGTTATTTAA TACACCAGTG AATGCAGTGT TCTGCCGGGT AGAAGGAGGA 
CAGATAGCTG CAATGATCTT CCTGTTTGTC ACCATGATAG TTTATCTCAT TAGTGCTTTG 
GTTTGCCTAA AGTTATGGAG GCATGAGGCA GCTCGGAGAC ATAGAGAATA TATGGAACAA 
CAGGAGTGTG AAATGGCCAC CAGTGGTGAC AGACAAAGAG ACTCAGAAGT TAATTTCAAG 
GAACTGAGAA CAGCAAAAAT GAAACCTGAA CTACTGAGTG GACACATCCC CCCAGGCCAC 
ATTCCTAAAC CTATCGTGAT GCCCGACTAT GTGGCAAAAT ACCCTGTGAT TCAGACAGAT 
GATGAGCGAG AACGCTATAA AGCTGTGTTC CAAGACCAGT TTTCAGAGTA CAAAGAGCTG 
TCTGCAGAAG TTCAGGCTGT CCTGAGGAAG TTTGATGAGC TGGATGCAGT GATGAGCAGA 
TTGCCACATC ATTCGGAAAG CCGACAGGAA CATGAGAGAA TTTCAAGAAT CCATGAAGAG 
TTTAAGAAAA AAAAGAATGA TCCTACATTT CTGGAAAAAA AAGAACGCTG TGATTACCTA 
AAGAATAAAC TTTCTCACAT AAAGCAAAGA ATTCAAGAAT ATGATAAAGT AATGAATTGG 
GATGTACAAG GTTATTCTTA A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001231663.1
CDS	75..1715
Translation	MSNDGRSRNRDRRYDEVPSDLPYQDTTIRTHPTLHDSERAVSADPLPPPPLPLQPPFGPDFYSSDTEEPAIAPDLKPVRRFVPDSWKNFFRGKKKDPEWDKPVSDIRYISDGVECSPPASPARPNHRSPLNSCKDPYGGSEGTFSSRKEADAVFPRDPYGSLDRHTQTVRTYSEKVEEYNLRYSYMKSWAGLLRILGVVELLLGAGVFACVTAYIHKDSEWYNLFGYSQPYGMGGVGGLGSMYGGYYYTGPKTPFVLVVAGLAWITTIIILVLGMSMYYRTILLDSNWWPLTEFGINVALFILYMAAAIVYVNDTNRGGLCYYPLFNTPVNAVFCRVEGGQIAAMIFLFVTMIVYLISALVCLKLWRHEAARRHREYMEQQECEMATSGDRQRDSEVNFKELRTAKMKPELLSGHIPPGHIPKPIVMPDYVAKYPVIQTDDERERYKAVFQDQFSEYKELSAEVQAVLRKFDELDAVMSRLPHHSESRQEHERISRIHEEFKKKKNDPTFLEKKERCDYLKNKLSHIKQRIQEYDKVMNWDVQGYS

Target ORF information:

RefSeq Version	NM_001244734.1
Organism	Homo sapiens(human)
Definition	Homo sapiens MARVEL domain containing 2 (MARVELD2), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001244734.1

ORF Insert Sequence:

ATGTCAAATG ATGGAAGATC CAGGAATCGG GACAGGCGCT ACGATGAGGT CCCAAGCGAC 
CTGCCCTATC AAGATACCAC CATAAGAACC CACCCAACTC TTCATGACAG TGAGCGGGCA 
GTGAGCGCTG ATCCCTTGCC ACCACCCCCT CTCCCATTAC AGCCACCATT CGGCCCAGAC 
TTCTACTCAA GTGACACAGA AGAACCAGCT ATAGCGCCAG ATCTCAAACC AGTAAGGCGC 
TTTGTCCCTG ACTCCTGGAA GAACTTTTTC AGAGGGAAGA AAAAGGACCC CGAATGGGAT 
AAGCCGGTGT CTGATATCAG GTACATCTCC GATGGAGTGG AGTGTTCACC ACCAGCCTCT 
CCAGCAAGAC CAAACCACCG TTCGCCCCTC AACTCCTGCA AAGATCCCTA CGGAGGGTCA 
GAAGGAACCT TTAGTTCCCG GAAAGAGGCT GACGCAGTGT TTCCCCGGGA TCCCTATGGA 
TCTCTAGACC GACACACACA AACAGTTCGA ACATACAGTG AGAAGGTGGA GGAGTATAAC 
CTGAGATACT CCTACATGAA GTCGTGGGCA GGCCTGCTGA GAATACTGGG TGTGGTGGAG 
CTGCTTTTGG GGGCCGGTGT CTTTGCTTGT GTCACAGCTT ACATTCACAA GGACAGTGAG 
TGGTACAACT TGTTTGGATA TTCACAACCG TATGGCATGG GAGGCGTTGG TGGATTGGGC 
AGTATGTATG GGGGCTATTA CTACACTGGC CCTAAGACCC CTTTTGTACT CGTGGTTGCT 
GGATTAGCTT GGATCACCAC CATTATTATT CTGGTTCTTG GCATGTCCAT GTATTACCGG 
ACCATTCTTC TGGACTCTAA TTGGTGGCCC CTAACTGAAT TTGGAATTAA CGTTGCCTTG 
TTTATTTTGT ATATGGCCGC AGCCATAGTC TATGTGAATG ATACCAACCG AGGTGGCCTC 
TGCTACTATC CGTTATTTAA TACACCAGTG AATGCAGTGT TCTGCCGGGT AGAAGGAGGA 
CAGATAGCTG CAATGATCTT CCTGTTTGTC ACCATGATAG TTTATCTCAT TAGTGCTTTG 
GTTTGCCTAA AGTTATGGAG GCATGAGGCA GCTCGGAGAC ATAGAGAATA TATGGAACAA 
CAGGAGTGTG AAATGGCCAC CAGTGGTGAC AGACAAAGAG ACTCAGAAGT TAATTTCAAG 
GAACTGAGAA CAGCAAAAAT GAAACCTGAA CTACTGAGTG GACACATCCC CCCAGGCCAC 
ATTCCTAAAC CTATCGTGAT GCCCGACTAT GTGGCAAAAT ACCCTGTGAT TCAGACAGAT 
GATGAGCGAG AACGCTATAA AGCTGTGTTC CAAGACCAGT TTTCAGAGTA CAAAGAGCTG 
TCTGCAGAAG TTCAGGCTGT CCTGAGGAAG TTTGATGAGC TGGATGCAGT GATGAGCAGA 
TTGCCACATC ATTCGGAAAG CCGACAGGAA CATGAGAGAA TTTCAAGAAT CCATGAAGAG 
TTTAAGAAAA AAAAGAATGA TCCTACATTT CTGGAAAAAA AAGAACGCTG TGATTACCTA 
AAGAATAAAC TTTCTCACAT AAAGCAAAGA ATTCAAGAAT ATGATAAAGT AATGAATTGG 
GATGTACAAG GTTATTCTTA A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

MARVELD2 ( NM_001244734.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_001231663.1 Homo sapiens MARVEL domain containing 2 (MARVELD2), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu10219
Clone ID Related Accession (Same CDS sequence)	XM_005248447.4 , NM_001244734.1 , NM_001244734.2
Accession Version	NM_001244734.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1641bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-08-07
Organism	Homo sapiens(human)
Product	MARVEL domain-containing protein 2 isoform 2
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BG943115.1, AC145146.2, DQ682657.1 and BC033689.1. On May 31, 2019 this sequence version replaced NM_001244734.1. Transcript Variant: This variant (2) lacks an alternate in-frame exon compared to variant 1. The resulting isoform (2) has the same N- and C-termini but is shorter compared to isoform 1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1803613.176169.1, DQ682657.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2142348, SAMEA2142363 [ECO:0000348] ##Evidence-Data-END##

ATGTCAAATG ATGGAAGATC CAGGAATCGG GACAGGCGCT ACGATGAGGT CCCAAGCGAC 
CTGCCCTATC AAGATACCAC CATAAGAACC CACCCAACTC TTCATGACAG TGAGCGGGCA 
GTGAGCGCTG ATCCCTTGCC ACCACCCCCT CTCCCATTAC AGCCACCATT CGGCCCAGAC 
TTCTACTCAA GTGACACAGA AGAACCAGCT ATAGCGCCAG ATCTCAAACC AGTAAGGCGC 
TTTGTCCCTG ACTCCTGGAA GAACTTTTTC AGAGGGAAGA AAAAGGACCC CGAATGGGAT 
AAGCCGGTGT CTGATATCAG GTACATCTCC GATGGAGTGG AGTGTTCACC ACCAGCCTCT 
CCAGCAAGAC CAAACCACCG TTCGCCCCTC AACTCCTGCA AAGATCCCTA CGGAGGGTCA 
GAAGGAACCT TTAGTTCCCG GAAAGAGGCT GACGCAGTGT TTCCCCGGGA TCCCTATGGA 
TCTCTAGACC GACACACACA AACAGTTCGA ACATACAGTG AGAAGGTGGA GGAGTATAAC 
CTGAGATACT CCTACATGAA GTCGTGGGCA GGCCTGCTGA GAATACTGGG TGTGGTGGAG 
CTGCTTTTGG GGGCCGGTGT CTTTGCTTGT GTCACAGCTT ACATTCACAA GGACAGTGAG 
TGGTACAACT TGTTTGGATA TTCACAACCG TATGGCATGG GAGGCGTTGG TGGATTGGGC 
AGTATGTATG GGGGCTATTA CTACACTGGC CCTAAGACCC CTTTTGTACT CGTGGTTGCT 
GGATTAGCTT GGATCACCAC CATTATTATT CTGGTTCTTG GCATGTCCAT GTATTACCGG 
ACCATTCTTC TGGACTCTAA TTGGTGGCCC CTAACTGAAT TTGGAATTAA CGTTGCCTTG 
TTTATTTTGT ATATGGCCGC AGCCATAGTC TATGTGAATG ATACCAACCG AGGTGGCCTC 
TGCTACTATC CGTTATTTAA TACACCAGTG AATGCAGTGT TCTGCCGGGT AGAAGGAGGA 
CAGATAGCTG CAATGATCTT CCTGTTTGTC ACCATGATAG TTTATCTCAT TAGTGCTTTG 
GTTTGCCTAA AGTTATGGAG GCATGAGGCA GCTCGGAGAC ATAGAGAATA TATGGAACAA 
CAGGAGTGTG AAATGGCCAC CAGTGGTGAC AGACAAAGAG ACTCAGAAGT TAATTTCAAG 
GAACTGAGAA CAGCAAAAAT GAAACCTGAA CTACTGAGTG GACACATCCC CCCAGGCCAC 
ATTCCTAAAC CTATCGTGAT GCCCGACTAT GTGGCAAAAT ACCCTGTGAT TCAGACAGAT 
GATGAGCGAG AACGCTATAA AGCTGTGTTC CAAGACCAGT TTTCAGAGTA CAAAGAGCTG 
TCTGCAGAAG TTCAGGCTGT CCTGAGGAAG TTTGATGAGC TGGATGCAGT GATGAGCAGA 
TTGCCACATC ATTCGGAAAG CCGACAGGAA CATGAGAGAA TTTCAAGAAT CCATGAAGAG 
TTTAAGAAAA AAAAGAATGA TCCTACATTT CTGGAAAAAA AAGAACGCTG TGATTACCTA 
AAGAATAAAC TTTCTCACAT AAAGCAAAGA ATTCAAGAAT ATGATAAAGT AATGAATTGG 
GATGTACAAG GTTATTCTTA A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001231663.1
CDS	71..1711
Translation	MSNDGRSRNRDRRYDEVPSDLPYQDTTIRTHPTLHDSERAVSADPLPPPPLPLQPPFGPDFYSSDTEEPAIAPDLKPVRRFVPDSWKNFFRGKKKDPEWDKPVSDIRYISDGVECSPPASPARPNHRSPLNSCKDPYGGSEGTFSSRKEADAVFPRDPYGSLDRHTQTVRTYSEKVEEYNLRYSYMKSWAGLLRILGVVELLLGAGVFACVTAYIHKDSEWYNLFGYSQPYGMGGVGGLGSMYGGYYYTGPKTPFVLVVAGLAWITTIIILVLGMSMYYRTILLDSNWWPLTEFGINVALFILYMAAAIVYVNDTNRGGLCYYPLFNTPVNAVFCRVEGGQIAAMIFLFVTMIVYLISALVCLKLWRHEAARRHREYMEQQECEMATSGDRQRDSEVNFKELRTAKMKPELLSGHIPPGHIPKPIVMPDYVAKYPVIQTDDERERYKAVFQDQFSEYKELSAEVQAVLRKFDELDAVMSRLPHHSESRQEHERISRIHEEFKKKKNDPTFLEKKERCDYLKNKLSHIKQRIQEYDKVMNWDVQGYS

Target ORF information:

RefSeq Version	NM_001244734.2
Organism	Homo sapiens(human)
Definition	Homo sapiens MARVEL domain containing 2 (MARVELD2), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001244734.2

ORF Insert Sequence:

ATGTCAAATG ATGGAAGATC CAGGAATCGG GACAGGCGCT ACGATGAGGT CCCAAGCGAC 
CTGCCCTATC AAGATACCAC CATAAGAACC CACCCAACTC TTCATGACAG TGAGCGGGCA 
GTGAGCGCTG ATCCCTTGCC ACCACCCCCT CTCCCATTAC AGCCACCATT CGGCCCAGAC 
TTCTACTCAA GTGACACAGA AGAACCAGCT ATAGCGCCAG ATCTCAAACC AGTAAGGCGC 
TTTGTCCCTG ACTCCTGGAA GAACTTTTTC AGAGGGAAGA AAAAGGACCC CGAATGGGAT 
AAGCCGGTGT CTGATATCAG GTACATCTCC GATGGAGTGG AGTGTTCACC ACCAGCCTCT 
CCAGCAAGAC CAAACCACCG TTCGCCCCTC AACTCCTGCA AAGATCCCTA CGGAGGGTCA 
GAAGGAACCT TTAGTTCCCG GAAAGAGGCT GACGCAGTGT TTCCCCGGGA TCCCTATGGA 
TCTCTAGACC GACACACACA AACAGTTCGA ACATACAGTG AGAAGGTGGA GGAGTATAAC 
CTGAGATACT CCTACATGAA GTCGTGGGCA GGCCTGCTGA GAATACTGGG TGTGGTGGAG 
CTGCTTTTGG GGGCCGGTGT CTTTGCTTGT GTCACAGCTT ACATTCACAA GGACAGTGAG 
TGGTACAACT TGTTTGGATA TTCACAACCG TATGGCATGG GAGGCGTTGG TGGATTGGGC 
AGTATGTATG GGGGCTATTA CTACACTGGC CCTAAGACCC CTTTTGTACT CGTGGTTGCT 
GGATTAGCTT GGATCACCAC CATTATTATT CTGGTTCTTG GCATGTCCAT GTATTACCGG 
ACCATTCTTC TGGACTCTAA TTGGTGGCCC CTAACTGAAT TTGGAATTAA CGTTGCCTTG 
TTTATTTTGT ATATGGCCGC AGCCATAGTC TATGTGAATG ATACCAACCG AGGTGGCCTC 
TGCTACTATC CGTTATTTAA TACACCAGTG AATGCAGTGT TCTGCCGGGT AGAAGGAGGA 
CAGATAGCTG CAATGATCTT CCTGTTTGTC ACCATGATAG TTTATCTCAT TAGTGCTTTG 
GTTTGCCTAA AGTTATGGAG GCATGAGGCA GCTCGGAGAC ATAGAGAATA TATGGAACAA 
CAGGAGTGTG AAATGGCCAC CAGTGGTGAC AGACAAAGAG ACTCAGAAGT TAATTTCAAG 
GAACTGAGAA CAGCAAAAAT GAAACCTGAA CTACTGAGTG GACACATCCC CCCAGGCCAC 
ATTCCTAAAC CTATCGTGAT GCCCGACTAT GTGGCAAAAT ACCCTGTGAT TCAGACAGAT 
GATGAGCGAG AACGCTATAA AGCTGTGTTC CAAGACCAGT TTTCAGAGTA CAAAGAGCTG 
TCTGCAGAAG TTCAGGCTGT CCTGAGGAAG TTTGATGAGC TGGATGCAGT GATGAGCAGA 
TTGCCACATC ATTCGGAAAG CCGACAGGAA CATGAGAGAA TTTCAAGAAT CCATGAAGAG 
TTTAAGAAAA AAAAGAATGA TCCTACATTT CTGGAAAAAA AAGAACGCTG TGATTACCTA 
AAGAATAAAC TTTCTCACAT AAAGCAAAGA ATTCAAGAAT ATGATAAAGT AATGAATTGG 
GATGTACAAG GTTATTCTTA A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

MARVELD2 ( NM_001038603.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_001033692.2 Homo sapiens MARVEL domain containing 2 (MARVELD2), transcript variant 1, mRNA.

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CloneID	OHu26081
Clone ID Related Accession (Same CDS sequence)	NM_001038603.2 , XM_005248445.4 , XM_005248446.4 , NM_001038603.3
Accession Version	NM_001038603.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1677bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-10-01
Organism	Homo sapiens(human)
Product	MARVEL domain-containing protein 2 isoform 1
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BG943115.1, BC033689.1 and AK292962.1. This sequence is a reference standard in the RefSeqGene project. On Feb 27, 2010 this sequence version replaced NM_001038603.1. Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC033689.1, SRR1660807.143266.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968540, SAMEA1968832 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGTCAAATG ATGGAAGATC CAGGAATCGG GACAGGCGCT ACGATGAGGT CCCAAGCGAC 
CTGCCCTATC AAGATACCAC CATAAGAACC CACCCAACTC TTCATGACAG TGAGCGGGCA 
GTGAGCGCTG ATCCCTTGCC ACCACCCCCT CTCCCATTAC AGCCACCATT CGGCCCAGAC 
TTCTACTCAA GTGACACAGA AGAACCAGCT ATAGCGCCAG ATCTCAAACC AGTAAGGCGC 
TTTGTCCCTG ACTCCTGGAA GAACTTTTTC AGAGGGAAGA AAAAGGACCC CGAATGGGAT 
AAGCCGGTGT CTGATATCAG GTACATCTCC GATGGAGTGG AGTGTTCACC ACCAGCCTCT 
CCAGCAAGAC CAAACCACCG TTCGCCCCTC AACTCCTGCA AAGATCCCTA CGGAGGGTCA 
GAAGGAACCT TTAGTTCCCG GAAAGAGGCT GACGCAGTGT TTCCCCGGGA TCCCTATGGA 
TCTCTAGACC GACACACACA AACAGTTCGA ACATACAGTG AGAAGGTGGA GGAGTATAAC 
CTGAGATACT CCTACATGAA GTCGTGGGCA GGCCTGCTGA GAATACTGGG TGTGGTGGAG 
CTGCTTTTGG GGGCCGGTGT CTTTGCTTGT GTCACAGCTT ACATTCACAA GGACAGTGAG 
TGGTACAACT TGTTTGGATA TTCACAACCG TATGGCATGG GAGGCGTTGG TGGATTGGGC 
AGTATGTATG GGGGCTATTA CTACACTGGC CCTAAGACCC CTTTTGTACT CGTGGTTGCT 
GGATTAGCTT GGATCACCAC CATTATTATT CTGGTTCTTG GCATGTCCAT GTATTACCGG 
ACCATTCTTC TGGACTCTAA TTGGTGGCCC CTAACTGAAT TTGGAATTAA CGTTGCCTTG 
TTTATTTTGT ATATGGCCGC AGCCATAGTC TATGTGAATG ATACCAACCG AGGTGGCCTC 
TGCTACTATC CGTTATTTAA TACACCAGTG AATGCAGTGT TCTGCCGGGT AGAAGGAGGA 
CAGATAGCTG CAATGATCTT CCTGTTTGTC ACCATGATAG TTTATCTCAT TAGTGCTTTG 
GTTTGCCTAA AGTTATGGAG GCATGAGGCA GCTCGGAGAC ATAGAGAATA TATGGAACAA 
CAGGAGATAA ATGAGCCATC ATTGTCATCG AAAAGGAAAA TGTGTGAAAT GGCCACCAGT 
GGTGACAGAC AAAGAGACTC AGAAGTTAAT TTCAAGGAAC TGAGAACAGC AAAAATGAAA 
CCTGAACTAC TGAGTGGACA CATCCCCCCA GGCCACATTC CTAAACCTAT CGTGATGCCC 
GACTATGTGG CAAAATACCC TGTGATTCAG ACAGATGATG AGCGAGAACG CTATAAAGCT 
GTGTTCCAAG ACCAGTTTTC AGAGTACAAA GAGCTGTCTG CAGAAGTTCA GGCTGTCCTG 
AGGAAGTTTG ATGAGCTGGA TGCAGTGATG AGCAGATTGC CACATCATTC GGAAAGCCGA 
CAGGAACATG AGAGAATTTC AAGAATCCAT GAAGAGTTTA AGAAAAAAAA GAATGATCCT 
ACATTTCTGG AAAAAAAAGA ACGCTGTGAT TACCTAAAGA ATAAACTTTC TCACATAAAG 
CAAAGAATTC AAGAATATGA TAAAGTAATG AATTGGGATG TACAAGGTTA TTCTTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001033692.2
CDS	75..1751
Translation	MSNDGRSRNRDRRYDEVPSDLPYQDTTIRTHPTLHDSERAVSADPLPPPPLPLQPPFGPDFYSSDTEEPAIAPDLKPVRRFVPDSWKNFFRGKKKDPEWDKPVSDIRYISDGVECSPPASPARPNHRSPLNSCKDPYGGSEGTFSSRKEADAVFPRDPYGSLDRHTQTVRTYSEKVEEYNLRYSYMKSWAGLLRILGVVELLLGAGVFACVTAYIHKDSEWYNLFGYSQPYGMGGVGGLGSMYGGYYYTGPKTPFVLVVAGLAWITTIIILVLGMSMYYRTILLDSNWWPLTEFGINVALFILYMAAAIVYVNDTNRGGLCYYPLFNTPVNAVFCRVEGGQIAAMIFLFVTMIVYLISALVCLKLWRHEAARRHREYMEQQEINEPSLSSKRKMCEMATSGDRQRDSEVNFKELRTAKMKPELLSGHIPPGHIPKPIVMPDYVAKYPVIQTDDERERYKAVFQDQFSEYKELSAEVQAVLRKFDELDAVMSRLPHHSESRQEHERISRIHEEFKKKKNDPTFLEKKERCDYLKNKLSHIKQRIQEYDKVMNWDVQGYS

Target ORF information:

RefSeq Version	NM_001038603.2
Organism	Homo sapiens(human)
Definition	Homo sapiens MARVEL domain containing 2 (MARVELD2), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001038603.2

ORF Insert Sequence:

ATGTCAAATG ATGGAAGATC CAGGAATCGG GACAGGCGCT ACGATGAGGT CCCAAGCGAC 
CTGCCCTATC AAGATACCAC CATAAGAACC CACCCAACTC TTCATGACAG TGAGCGGGCA 
GTGAGCGCTG ATCCCTTGCC ACCACCCCCT CTCCCATTAC AGCCACCATT CGGCCCAGAC 
TTCTACTCAA GTGACACAGA AGAACCAGCT ATAGCGCCAG ATCTCAAACC AGTAAGGCGC 
TTTGTCCCTG ACTCCTGGAA GAACTTTTTC AGAGGGAAGA AAAAGGACCC CGAATGGGAT 
AAGCCGGTGT CTGATATCAG GTACATCTCC GATGGAGTGG AGTGTTCACC ACCAGCCTCT 
CCAGCAAGAC CAAACCACCG TTCGCCCCTC AACTCCTGCA AAGATCCCTA CGGAGGGTCA 
GAAGGAACCT TTAGTTCCCG GAAAGAGGCT GACGCAGTGT TTCCCCGGGA TCCCTATGGA 
TCTCTAGACC GACACACACA AACAGTTCGA ACATACAGTG AGAAGGTGGA GGAGTATAAC 
CTGAGATACT CCTACATGAA GTCGTGGGCA GGCCTGCTGA GAATACTGGG TGTGGTGGAG 
CTGCTTTTGG GGGCCGGTGT CTTTGCTTGT GTCACAGCTT ACATTCACAA GGACAGTGAG 
TGGTACAACT TGTTTGGATA TTCACAACCG TATGGCATGG GAGGCGTTGG TGGATTGGGC 
AGTATGTATG GGGGCTATTA CTACACTGGC CCTAAGACCC CTTTTGTACT CGTGGTTGCT 
GGATTAGCTT GGATCACCAC CATTATTATT CTGGTTCTTG GCATGTCCAT GTATTACCGG 
ACCATTCTTC TGGACTCTAA TTGGTGGCCC CTAACTGAAT TTGGAATTAA CGTTGCCTTG 
TTTATTTTGT ATATGGCCGC AGCCATAGTC TATGTGAATG ATACCAACCG AGGTGGCCTC 
TGCTACTATC CGTTATTTAA TACACCAGTG AATGCAGTGT TCTGCCGGGT AGAAGGAGGA 
CAGATAGCTG CAATGATCTT CCTGTTTGTC ACCATGATAG TTTATCTCAT TAGTGCTTTG 
GTTTGCCTAA AGTTATGGAG GCATGAGGCA GCTCGGAGAC ATAGAGAATA TATGGAACAA 
CAGGAGATAA ATGAGCCATC ATTGTCATCG AAAAGGAAAA TGTGTGAAAT GGCCACCAGT 
GGTGACAGAC AAAGAGACTC AGAAGTTAAT TTCAAGGAAC TGAGAACAGC AAAAATGAAA 
CCTGAACTAC TGAGTGGACA CATCCCCCCA GGCCACATTC CTAAACCTAT CGTGATGCCC 
GACTATGTGG CAAAATACCC TGTGATTCAG ACAGATGATG AGCGAGAACG CTATAAAGCT 
GTGTTCCAAG ACCAGTTTTC AGAGTACAAA GAGCTGTCTG CAGAAGTTCA GGCTGTCCTG 
AGGAAGTTTG ATGAGCTGGA TGCAGTGATG AGCAGATTGC CACATCATTC GGAAAGCCGA 
CAGGAACATG AGAGAATTTC AAGAATCCAT GAAGAGTTTA AGAAAAAAAA GAATGATCCT 
ACATTTCTGG AAAAAAAAGA ACGCTGTGAT TACCTAAAGA ATAAACTTTC TCACATAAAG 
CAAAGAATTC AAGAATATGA TAAAGTAATG AATTGGGATG TACAAGGTTA TTCTTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

MARVELD2 ( XM_005248447.4 ) cDNA ORF clone, Homo sapiens(human) -> XP_005248504.1 Homo sapiens MARVEL domain containing 2 (MARVELD2), transcript variant X3, mRNA.

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CloneID	OHu10219
Clone ID Related Accession (Same CDS sequence)	XM_005248447.4 , NM_001244734.1 , NM_001244734.2
Accession Version	XM_005248447.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1641bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	MARVEL domain-containing protein 2 isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000005.10) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 6, 2016 this sequence version replaced XM_005248447.3. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGTCAAATG ATGGAAGATC CAGGAATCGG GACAGGCGCT ACGATGAGGT CCCAAGCGAC 
CTGCCCTATC AAGATACCAC CATAAGAACC CACCCAACTC TTCATGACAG TGAGCGGGCA 
GTGAGCGCTG ATCCCTTGCC ACCACCCCCT CTCCCATTAC AGCCACCATT CGGCCCAGAC 
TTCTACTCAA GTGACACAGA AGAACCAGCT ATAGCGCCAG ATCTCAAACC AGTAAGGCGC 
TTTGTCCCTG ACTCCTGGAA GAACTTTTTC AGAGGGAAGA AAAAGGACCC CGAATGGGAT 
AAGCCGGTGT CTGATATCAG GTACATCTCC GATGGAGTGG AGTGTTCACC ACCAGCCTCT 
CCAGCAAGAC CAAACCACCG TTCGCCCCTC AACTCCTGCA AAGATCCCTA CGGAGGGTCA 
GAAGGAACCT TTAGTTCCCG GAAAGAGGCT GACGCAGTGT TTCCCCGGGA TCCCTATGGA 
TCTCTAGACC GACACACACA AACAGTTCGA ACATACAGTG AGAAGGTGGA GGAGTATAAC 
CTGAGATACT CCTACATGAA GTCGTGGGCA GGCCTGCTGA GAATACTGGG TGTGGTGGAG 
CTGCTTTTGG GGGCCGGTGT CTTTGCTTGT GTCACAGCTT ACATTCACAA GGACAGTGAG 
TGGTACAACT TGTTTGGATA TTCACAACCG TATGGCATGG GAGGCGTTGG TGGATTGGGC 
AGTATGTATG GGGGCTATTA CTACACTGGC CCTAAGACCC CTTTTGTACT CGTGGTTGCT 
GGATTAGCTT GGATCACCAC CATTATTATT CTGGTTCTTG GCATGTCCAT GTATTACCGG 
ACCATTCTTC TGGACTCTAA TTGGTGGCCC CTAACTGAAT TTGGAATTAA CGTTGCCTTG 
TTTATTTTGT ATATGGCCGC AGCCATAGTC TATGTGAATG ATACCAACCG AGGTGGCCTC 
TGCTACTATC CGTTATTTAA TACACCAGTG AATGCAGTGT TCTGCCGGGT AGAAGGAGGA 
CAGATAGCTG CAATGATCTT CCTGTTTGTC ACCATGATAG TTTATCTCAT TAGTGCTTTG 
GTTTGCCTAA AGTTATGGAG GCATGAGGCA GCTCGGAGAC ATAGAGAATA TATGGAACAA 
CAGGAGTGTG AAATGGCCAC CAGTGGTGAC AGACAAAGAG ACTCAGAAGT TAATTTCAAG 
GAACTGAGAA CAGCAAAAAT GAAACCTGAA CTACTGAGTG GACACATCCC CCCAGGCCAC 
ATTCCTAAAC CTATCGTGAT GCCCGACTAT GTGGCAAAAT ACCCTGTGAT TCAGACAGAT 
GATGAGCGAG AACGCTATAA AGCTGTGTTC CAAGACCAGT TTTCAGAGTA CAAAGAGCTG 
TCTGCAGAAG TTCAGGCTGT CCTGAGGAAG TTTGATGAGC TGGATGCAGT GATGAGCAGA 
TTGCCACATC ATTCGGAAAG CCGACAGGAA CATGAGAGAA TTTCAAGAAT CCATGAAGAG 
TTTAAGAAAA AAAAGAATGA TCCTACATTT CTGGAAAAAA AAGAACGCTG TGATTACCTA 
AAGAATAAAC TTTCTCACAT AAAGCAAAGA ATTCAAGAAT ATGATAAAGT AATGAATTGG 
GATGTACAAG GTTATTCTTA A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_005248504.1
CDS	370..2010
Translation	MSNDGRSRNRDRRYDEVPSDLPYQDTTIRTHPTLHDSERAVSADPLPPPPLPLQPPFGPDFYSSDTEEPAIAPDLKPVRRFVPDSWKNFFRGKKKDPEWDKPVSDIRYISDGVECSPPASPARPNHRSPLNSCKDPYGGSEGTFSSRKEADAVFPRDPYGSLDRHTQTVRTYSEKVEEYNLRYSYMKSWAGLLRILGVVELLLGAGVFACVTAYIHKDSEWYNLFGYSQPYGMGGVGGLGSMYGGYYYTGPKTPFVLVVAGLAWITTIIILVLGMSMYYRTILLDSNWWPLTEFGINVALFILYMAAAIVYVNDTNRGGLCYYPLFNTPVNAVFCRVEGGQIAAMIFLFVTMIVYLISALVCLKLWRHEAARRHREYMEQQECEMATSGDRQRDSEVNFKELRTAKMKPELLSGHIPPGHIPKPIVMPDYVAKYPVIQTDDERERYKAVFQDQFSEYKELSAEVQAVLRKFDELDAVMSRLPHHSESRQEHERISRIHEEFKKKKNDPTFLEKKERCDYLKNKLSHIKQRIQEYDKVMNWDVQGYS

Target ORF information:

RefSeq Version	XM_005248447.4
Organism	Homo sapiens(human)
Definition	Homo sapiens MARVEL domain containing 2 (MARVELD2), transcript variant X3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_005248447.4

ORF Insert Sequence:

ATGTCAAATG ATGGAAGATC CAGGAATCGG GACAGGCGCT ACGATGAGGT CCCAAGCGAC 
CTGCCCTATC AAGATACCAC CATAAGAACC CACCCAACTC TTCATGACAG TGAGCGGGCA 
GTGAGCGCTG ATCCCTTGCC ACCACCCCCT CTCCCATTAC AGCCACCATT CGGCCCAGAC 
TTCTACTCAA GTGACACAGA AGAACCAGCT ATAGCGCCAG ATCTCAAACC AGTAAGGCGC 
TTTGTCCCTG ACTCCTGGAA GAACTTTTTC AGAGGGAAGA AAAAGGACCC CGAATGGGAT 
AAGCCGGTGT CTGATATCAG GTACATCTCC GATGGAGTGG AGTGTTCACC ACCAGCCTCT 
CCAGCAAGAC CAAACCACCG TTCGCCCCTC AACTCCTGCA AAGATCCCTA CGGAGGGTCA 
GAAGGAACCT TTAGTTCCCG GAAAGAGGCT GACGCAGTGT TTCCCCGGGA TCCCTATGGA 
TCTCTAGACC GACACACACA AACAGTTCGA ACATACAGTG AGAAGGTGGA GGAGTATAAC 
CTGAGATACT CCTACATGAA GTCGTGGGCA GGCCTGCTGA GAATACTGGG TGTGGTGGAG 
CTGCTTTTGG GGGCCGGTGT CTTTGCTTGT GTCACAGCTT ACATTCACAA GGACAGTGAG 
TGGTACAACT TGTTTGGATA TTCACAACCG TATGGCATGG GAGGCGTTGG TGGATTGGGC 
AGTATGTATG GGGGCTATTA CTACACTGGC CCTAAGACCC CTTTTGTACT CGTGGTTGCT 
GGATTAGCTT GGATCACCAC CATTATTATT CTGGTTCTTG GCATGTCCAT GTATTACCGG 
ACCATTCTTC TGGACTCTAA TTGGTGGCCC CTAACTGAAT TTGGAATTAA CGTTGCCTTG 
TTTATTTTGT ATATGGCCGC AGCCATAGTC TATGTGAATG ATACCAACCG AGGTGGCCTC 
TGCTACTATC CGTTATTTAA TACACCAGTG AATGCAGTGT TCTGCCGGGT AGAAGGAGGA 
CAGATAGCTG CAATGATCTT CCTGTTTGTC ACCATGATAG TTTATCTCAT TAGTGCTTTG 
GTTTGCCTAA AGTTATGGAG GCATGAGGCA GCTCGGAGAC ATAGAGAATA TATGGAACAA 
CAGGAGTGTG AAATGGCCAC CAGTGGTGAC AGACAAAGAG ACTCAGAAGT TAATTTCAAG 
GAACTGAGAA CAGCAAAAAT GAAACCTGAA CTACTGAGTG GACACATCCC CCCAGGCCAC 
ATTCCTAAAC CTATCGTGAT GCCCGACTAT GTGGCAAAAT ACCCTGTGAT TCAGACAGAT 
GATGAGCGAG AACGCTATAA AGCTGTGTTC CAAGACCAGT TTTCAGAGTA CAAAGAGCTG 
TCTGCAGAAG TTCAGGCTGT CCTGAGGAAG TTTGATGAGC TGGATGCAGT GATGAGCAGA 
TTGCCACATC ATTCGGAAAG CCGACAGGAA CATGAGAGAA TTTCAAGAAT CCATGAAGAG 
TTTAAGAAAA AAAAGAATGA TCCTACATTT CTGGAAAAAA AAGAACGCTG TGATTACCTA 
AAGAATAAAC TTTCTCACAT AAAGCAAAGA ATTCAAGAAT ATGATAAAGT AATGAATTGG 
GATGTACAAG GTTATTCTTA A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

MARVELD2 ( XM_005248445.4 ) cDNA ORF clone, Homo sapiens(human) -> XP_005248502.1 Homo sapiens MARVEL domain containing 2 (MARVELD2), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OHu26081
Clone ID Related Accession (Same CDS sequence)	NM_001038603.2 , XM_005248445.4 , XM_005248446.4 , NM_001038603.3
Accession Version	XM_005248445.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1677bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	MARVEL domain-containing protein 2 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000005.10) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 6, 2016 this sequence version replaced XM_005248445.3. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGTCAAATG ATGGAAGATC CAGGAATCGG GACAGGCGCT ACGATGAGGT CCCAAGCGAC 
CTGCCCTATC AAGATACCAC CATAAGAACC CACCCAACTC TTCATGACAG TGAGCGGGCA 
GTGAGCGCTG ATCCCTTGCC ACCACCCCCT CTCCCATTAC AGCCACCATT CGGCCCAGAC 
TTCTACTCAA GTGACACAGA AGAACCAGCT ATAGCGCCAG ATCTCAAACC AGTAAGGCGC 
TTTGTCCCTG ACTCCTGGAA GAACTTTTTC AGAGGGAAGA AAAAGGACCC CGAATGGGAT 
AAGCCGGTGT CTGATATCAG GTACATCTCC GATGGAGTGG AGTGTTCACC ACCAGCCTCT 
CCAGCAAGAC CAAACCACCG TTCGCCCCTC AACTCCTGCA AAGATCCCTA CGGAGGGTCA 
GAAGGAACCT TTAGTTCCCG GAAAGAGGCT GACGCAGTGT TTCCCCGGGA TCCCTATGGA 
TCTCTAGACC GACACACACA AACAGTTCGA ACATACAGTG AGAAGGTGGA GGAGTATAAC 
CTGAGATACT CCTACATGAA GTCGTGGGCA GGCCTGCTGA GAATACTGGG TGTGGTGGAG 
CTGCTTTTGG GGGCCGGTGT CTTTGCTTGT GTCACAGCTT ACATTCACAA GGACAGTGAG 
TGGTACAACT TGTTTGGATA TTCACAACCG TATGGCATGG GAGGCGTTGG TGGATTGGGC 
AGTATGTATG GGGGCTATTA CTACACTGGC CCTAAGACCC CTTTTGTACT CGTGGTTGCT 
GGATTAGCTT GGATCACCAC CATTATTATT CTGGTTCTTG GCATGTCCAT GTATTACCGG 
ACCATTCTTC TGGACTCTAA TTGGTGGCCC CTAACTGAAT TTGGAATTAA CGTTGCCTTG 
TTTATTTTGT ATATGGCCGC AGCCATAGTC TATGTGAATG ATACCAACCG AGGTGGCCTC 
TGCTACTATC CGTTATTTAA TACACCAGTG AATGCAGTGT TCTGCCGGGT AGAAGGAGGA 
CAGATAGCTG CAATGATCTT CCTGTTTGTC ACCATGATAG TTTATCTCAT TAGTGCTTTG 
GTTTGCCTAA AGTTATGGAG GCATGAGGCA GCTCGGAGAC ATAGAGAATA TATGGAACAA 
CAGGAGATAA ATGAGCCATC ATTGTCATCG AAAAGGAAAA TGTGTGAAAT GGCCACCAGT 
GGTGACAGAC AAAGAGACTC AGAAGTTAAT TTCAAGGAAC TGAGAACAGC AAAAATGAAA 
CCTGAACTAC TGAGTGGACA CATCCCCCCA GGCCACATTC CTAAACCTAT CGTGATGCCC 
GACTATGTGG CAAAATACCC TGTGATTCAG ACAGATGATG AGCGAGAACG CTATAAAGCT 
GTGTTCCAAG ACCAGTTTTC AGAGTACAAA GAGCTGTCTG CAGAAGTTCA GGCTGTCCTG 
AGGAAGTTTG ATGAGCTGGA TGCAGTGATG AGCAGATTGC CACATCATTC GGAAAGCCGA 
CAGGAACATG AGAGAATTTC AAGAATCCAT GAAGAGTTTA AGAAAAAAAA GAATGATCCT 
ACATTTCTGG AAAAAAAAGA ACGCTGTGAT TACCTAAAGA ATAAACTTTC TCACATAAAG 
CAAAGAATTC AAGAATATGA TAAAGTAATG AATTGGGATG TACAAGGTTA TTCTTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_005248502.1
CDS	369..2045
Translation	MSNDGRSRNRDRRYDEVPSDLPYQDTTIRTHPTLHDSERAVSADPLPPPPLPLQPPFGPDFYSSDTEEPAIAPDLKPVRRFVPDSWKNFFRGKKKDPEWDKPVSDIRYISDGVECSPPASPARPNHRSPLNSCKDPYGGSEGTFSSRKEADAVFPRDPYGSLDRHTQTVRTYSEKVEEYNLRYSYMKSWAGLLRILGVVELLLGAGVFACVTAYIHKDSEWYNLFGYSQPYGMGGVGGLGSMYGGYYYTGPKTPFVLVVAGLAWITTIIILVLGMSMYYRTILLDSNWWPLTEFGINVALFILYMAAAIVYVNDTNRGGLCYYPLFNTPVNAVFCRVEGGQIAAMIFLFVTMIVYLISALVCLKLWRHEAARRHREYMEQQEINEPSLSSKRKMCEMATSGDRQRDSEVNFKELRTAKMKPELLSGHIPPGHIPKPIVMPDYVAKYPVIQTDDERERYKAVFQDQFSEYKELSAEVQAVLRKFDELDAVMSRLPHHSESRQEHERISRIHEEFKKKKNDPTFLEKKERCDYLKNKLSHIKQRIQEYDKVMNWDVQGYS

Target ORF information:

RefSeq Version	XM_005248445.4
Organism	Homo sapiens(human)
Definition	Homo sapiens MARVEL domain containing 2 (MARVELD2), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_005248445.4

ORF Insert Sequence:

ATGTCAAATG ATGGAAGATC CAGGAATCGG GACAGGCGCT ACGATGAGGT CCCAAGCGAC 
CTGCCCTATC AAGATACCAC CATAAGAACC CACCCAACTC TTCATGACAG TGAGCGGGCA 
GTGAGCGCTG ATCCCTTGCC ACCACCCCCT CTCCCATTAC AGCCACCATT CGGCCCAGAC 
TTCTACTCAA GTGACACAGA AGAACCAGCT ATAGCGCCAG ATCTCAAACC AGTAAGGCGC 
TTTGTCCCTG ACTCCTGGAA GAACTTTTTC AGAGGGAAGA AAAAGGACCC CGAATGGGAT 
AAGCCGGTGT CTGATATCAG GTACATCTCC GATGGAGTGG AGTGTTCACC ACCAGCCTCT 
CCAGCAAGAC CAAACCACCG TTCGCCCCTC AACTCCTGCA AAGATCCCTA CGGAGGGTCA 
GAAGGAACCT TTAGTTCCCG GAAAGAGGCT GACGCAGTGT TTCCCCGGGA TCCCTATGGA 
TCTCTAGACC GACACACACA AACAGTTCGA ACATACAGTG AGAAGGTGGA GGAGTATAAC 
CTGAGATACT CCTACATGAA GTCGTGGGCA GGCCTGCTGA GAATACTGGG TGTGGTGGAG 
CTGCTTTTGG GGGCCGGTGT CTTTGCTTGT GTCACAGCTT ACATTCACAA GGACAGTGAG 
TGGTACAACT TGTTTGGATA TTCACAACCG TATGGCATGG GAGGCGTTGG TGGATTGGGC 
AGTATGTATG GGGGCTATTA CTACACTGGC CCTAAGACCC CTTTTGTACT CGTGGTTGCT 
GGATTAGCTT GGATCACCAC CATTATTATT CTGGTTCTTG GCATGTCCAT GTATTACCGG 
ACCATTCTTC TGGACTCTAA TTGGTGGCCC CTAACTGAAT TTGGAATTAA CGTTGCCTTG 
TTTATTTTGT ATATGGCCGC AGCCATAGTC TATGTGAATG ATACCAACCG AGGTGGCCTC 
TGCTACTATC CGTTATTTAA TACACCAGTG AATGCAGTGT TCTGCCGGGT AGAAGGAGGA 
CAGATAGCTG CAATGATCTT CCTGTTTGTC ACCATGATAG TTTATCTCAT TAGTGCTTTG 
GTTTGCCTAA AGTTATGGAG GCATGAGGCA GCTCGGAGAC ATAGAGAATA TATGGAACAA 
CAGGAGATAA ATGAGCCATC ATTGTCATCG AAAAGGAAAA TGTGTGAAAT GGCCACCAGT 
GGTGACAGAC AAAGAGACTC AGAAGTTAAT TTCAAGGAAC TGAGAACAGC AAAAATGAAA 
CCTGAACTAC TGAGTGGACA CATCCCCCCA GGCCACATTC CTAAACCTAT CGTGATGCCC 
GACTATGTGG CAAAATACCC TGTGATTCAG ACAGATGATG AGCGAGAACG CTATAAAGCT 
GTGTTCCAAG ACCAGTTTTC AGAGTACAAA GAGCTGTCTG CAGAAGTTCA GGCTGTCCTG 
AGGAAGTTTG ATGAGCTGGA TGCAGTGATG AGCAGATTGC CACATCATTC GGAAAGCCGA 
CAGGAACATG AGAGAATTTC AAGAATCCAT GAAGAGTTTA AGAAAAAAAA GAATGATCCT 
ACATTTCTGG AAAAAAAAGA ACGCTGTGAT TACCTAAAGA ATAAACTTTC TCACATAAAG 
CAAAGAATTC AAGAATATGA TAAAGTAATG AATTGGGATG TACAAGGTTA TTCTTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

MARVELD2 ( XM_005248446.4 ) cDNA ORF clone, Homo sapiens(human) -> XP_005248503.1 Homo sapiens MARVEL domain containing 2 (MARVELD2), transcript variant X2, mRNA.

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CloneID	OHu26081
Clone ID Related Accession (Same CDS sequence)	NM_001038603.2 , XM_005248445.4 , XM_005248446.4 , NM_001038603.3
Accession Version	XM_005248446.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1677bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	MARVEL domain-containing protein 2 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000005.10) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 6, 2016 this sequence version replaced XM_005248446.3. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGTCAAATG ATGGAAGATC CAGGAATCGG GACAGGCGCT ACGATGAGGT CCCAAGCGAC 
CTGCCCTATC AAGATACCAC CATAAGAACC CACCCAACTC TTCATGACAG TGAGCGGGCA 
GTGAGCGCTG ATCCCTTGCC ACCACCCCCT CTCCCATTAC AGCCACCATT CGGCCCAGAC 
TTCTACTCAA GTGACACAGA AGAACCAGCT ATAGCGCCAG ATCTCAAACC AGTAAGGCGC 
TTTGTCCCTG ACTCCTGGAA GAACTTTTTC AGAGGGAAGA AAAAGGACCC CGAATGGGAT 
AAGCCGGTGT CTGATATCAG GTACATCTCC GATGGAGTGG AGTGTTCACC ACCAGCCTCT 
CCAGCAAGAC CAAACCACCG TTCGCCCCTC AACTCCTGCA AAGATCCCTA CGGAGGGTCA 
GAAGGAACCT TTAGTTCCCG GAAAGAGGCT GACGCAGTGT TTCCCCGGGA TCCCTATGGA 
TCTCTAGACC GACACACACA AACAGTTCGA ACATACAGTG AGAAGGTGGA GGAGTATAAC 
CTGAGATACT CCTACATGAA GTCGTGGGCA GGCCTGCTGA GAATACTGGG TGTGGTGGAG 
CTGCTTTTGG GGGCCGGTGT CTTTGCTTGT GTCACAGCTT ACATTCACAA GGACAGTGAG 
TGGTACAACT TGTTTGGATA TTCACAACCG TATGGCATGG GAGGCGTTGG TGGATTGGGC 
AGTATGTATG GGGGCTATTA CTACACTGGC CCTAAGACCC CTTTTGTACT CGTGGTTGCT 
GGATTAGCTT GGATCACCAC CATTATTATT CTGGTTCTTG GCATGTCCAT GTATTACCGG 
ACCATTCTTC TGGACTCTAA TTGGTGGCCC CTAACTGAAT TTGGAATTAA CGTTGCCTTG 
TTTATTTTGT ATATGGCCGC AGCCATAGTC TATGTGAATG ATACCAACCG AGGTGGCCTC 
TGCTACTATC CGTTATTTAA TACACCAGTG AATGCAGTGT TCTGCCGGGT AGAAGGAGGA 
CAGATAGCTG CAATGATCTT CCTGTTTGTC ACCATGATAG TTTATCTCAT TAGTGCTTTG 
GTTTGCCTAA AGTTATGGAG GCATGAGGCA GCTCGGAGAC ATAGAGAATA TATGGAACAA 
CAGGAGATAA ATGAGCCATC ATTGTCATCG AAAAGGAAAA TGTGTGAAAT GGCCACCAGT 
GGTGACAGAC AAAGAGACTC AGAAGTTAAT TTCAAGGAAC TGAGAACAGC AAAAATGAAA 
CCTGAACTAC TGAGTGGACA CATCCCCCCA GGCCACATTC CTAAACCTAT CGTGATGCCC 
GACTATGTGG CAAAATACCC TGTGATTCAG ACAGATGATG AGCGAGAACG CTATAAAGCT 
GTGTTCCAAG ACCAGTTTTC AGAGTACAAA GAGCTGTCTG CAGAAGTTCA GGCTGTCCTG 
AGGAAGTTTG ATGAGCTGGA TGCAGTGATG AGCAGATTGC CACATCATTC GGAAAGCCGA 
CAGGAACATG AGAGAATTTC AAGAATCCAT GAAGAGTTTA AGAAAAAAAA GAATGATCCT 
ACATTTCTGG AAAAAAAAGA ACGCTGTGAT TACCTAAAGA ATAAACTTTC TCACATAAAG 
CAAAGAATTC AAGAATATGA TAAAGTAATG AATTGGGATG TACAAGGTTA TTCTTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_005248503.1
CDS	163..1839
Translation	MSNDGRSRNRDRRYDEVPSDLPYQDTTIRTHPTLHDSERAVSADPLPPPPLPLQPPFGPDFYSSDTEEPAIAPDLKPVRRFVPDSWKNFFRGKKKDPEWDKPVSDIRYISDGVECSPPASPARPNHRSPLNSCKDPYGGSEGTFSSRKEADAVFPRDPYGSLDRHTQTVRTYSEKVEEYNLRYSYMKSWAGLLRILGVVELLLGAGVFACVTAYIHKDSEWYNLFGYSQPYGMGGVGGLGSMYGGYYYTGPKTPFVLVVAGLAWITTIIILVLGMSMYYRTILLDSNWWPLTEFGINVALFILYMAAAIVYVNDTNRGGLCYYPLFNTPVNAVFCRVEGGQIAAMIFLFVTMIVYLISALVCLKLWRHEAARRHREYMEQQEINEPSLSSKRKMCEMATSGDRQRDSEVNFKELRTAKMKPELLSGHIPPGHIPKPIVMPDYVAKYPVIQTDDERERYKAVFQDQFSEYKELSAEVQAVLRKFDELDAVMSRLPHHSESRQEHERISRIHEEFKKKKNDPTFLEKKERCDYLKNKLSHIKQRIQEYDKVMNWDVQGYS

Target ORF information:

RefSeq Version	XM_005248446.4
Organism	Homo sapiens(human)
Definition	Homo sapiens MARVEL domain containing 2 (MARVELD2), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_005248446.4

ORF Insert Sequence:

ATGTCAAATG ATGGAAGATC CAGGAATCGG GACAGGCGCT ACGATGAGGT CCCAAGCGAC 
CTGCCCTATC AAGATACCAC CATAAGAACC CACCCAACTC TTCATGACAG TGAGCGGGCA 
GTGAGCGCTG ATCCCTTGCC ACCACCCCCT CTCCCATTAC AGCCACCATT CGGCCCAGAC 
TTCTACTCAA GTGACACAGA AGAACCAGCT ATAGCGCCAG ATCTCAAACC AGTAAGGCGC 
TTTGTCCCTG ACTCCTGGAA GAACTTTTTC AGAGGGAAGA AAAAGGACCC CGAATGGGAT 
AAGCCGGTGT CTGATATCAG GTACATCTCC GATGGAGTGG AGTGTTCACC ACCAGCCTCT 
CCAGCAAGAC CAAACCACCG TTCGCCCCTC AACTCCTGCA AAGATCCCTA CGGAGGGTCA 
GAAGGAACCT TTAGTTCCCG GAAAGAGGCT GACGCAGTGT TTCCCCGGGA TCCCTATGGA 
TCTCTAGACC GACACACACA AACAGTTCGA ACATACAGTG AGAAGGTGGA GGAGTATAAC 
CTGAGATACT CCTACATGAA GTCGTGGGCA GGCCTGCTGA GAATACTGGG TGTGGTGGAG 
CTGCTTTTGG GGGCCGGTGT CTTTGCTTGT GTCACAGCTT ACATTCACAA GGACAGTGAG 
TGGTACAACT TGTTTGGATA TTCACAACCG TATGGCATGG GAGGCGTTGG TGGATTGGGC 
AGTATGTATG GGGGCTATTA CTACACTGGC CCTAAGACCC CTTTTGTACT CGTGGTTGCT 
GGATTAGCTT GGATCACCAC CATTATTATT CTGGTTCTTG GCATGTCCAT GTATTACCGG 
ACCATTCTTC TGGACTCTAA TTGGTGGCCC CTAACTGAAT TTGGAATTAA CGTTGCCTTG 
TTTATTTTGT ATATGGCCGC AGCCATAGTC TATGTGAATG ATACCAACCG AGGTGGCCTC 
TGCTACTATC CGTTATTTAA TACACCAGTG AATGCAGTGT TCTGCCGGGT AGAAGGAGGA 
CAGATAGCTG CAATGATCTT CCTGTTTGTC ACCATGATAG TTTATCTCAT TAGTGCTTTG 
GTTTGCCTAA AGTTATGGAG GCATGAGGCA GCTCGGAGAC ATAGAGAATA TATGGAACAA 
CAGGAGATAA ATGAGCCATC ATTGTCATCG AAAAGGAAAA TGTGTGAAAT GGCCACCAGT 
GGTGACAGAC AAAGAGACTC AGAAGTTAAT TTCAAGGAAC TGAGAACAGC AAAAATGAAA 
CCTGAACTAC TGAGTGGACA CATCCCCCCA GGCCACATTC CTAAACCTAT CGTGATGCCC 
GACTATGTGG CAAAATACCC TGTGATTCAG ACAGATGATG AGCGAGAACG CTATAAAGCT 
GTGTTCCAAG ACCAGTTTTC AGAGTACAAA GAGCTGTCTG CAGAAGTTCA GGCTGTCCTG 
AGGAAGTTTG ATGAGCTGGA TGCAGTGATG AGCAGATTGC CACATCATTC GGAAAGCCGA 
CAGGAACATG AGAGAATTTC AAGAATCCAT GAAGAGTTTA AGAAAAAAAA GAATGATCCT 
ACATTTCTGG AAAAAAAAGA ACGCTGTGAT TACCTAAAGA ATAAACTTTC TCACATAAAG 
CAAAGAATTC AAGAATATGA TAAAGTAATG AATTGGGATG TACAAGGTTA TTCTTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Crystal structure of the tricellulin C-terminal coiled-coil domain reveals a unique mode of dimerization.
Annals of the New York Academy of Sciences1405(1)147-159(2017 Oct)
Schuetz A,Radusheva V,Krug SM,Heinemann U

Contribution of the tricellular tight junction to paracellular permeability in leaky and tight epithelia.
Annals of the New York Academy of Sciences1397(1)219-230(2017 Jun)
Krug SM

Tricellulin is regulated via interleukin-13-receptor ?2, affects macromolecule uptake, and is decreased in ulcerative colitis.
Mucosal immunology(2017 Jun)
Krug SM,Bojarski C,Fromm A,Lee IM,Dames P,Richter JF,Turner JR,Fromm M,Schulzke JD

Tricellulin is a target of the ubiquitin ligase Itch.
Annals of the New York Academy of Sciences1397(1)157-168(2017 Jun)
Jennek S,Mittag S,Reiche J,Westphal JK,Seelk S,D?rfel MJ,Pfirrmann T,Friedrich K,Sch?tz A,Heinemann U,Huber O

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MARVELD2 cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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