Gene Symbol | CX3CR1 |
Entrez Gene ID | 1524 |
Full Name | C-X3-C motif chemokine receptor 1 |
Synonyms | CCRL1,CMKBRL1,CMKDR1,GPR13,GPRV28,V28 |
General protein information |
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Gene Type | protein-coding |
Organism | Homo sapiens(human) |
Genome | |
Summary | Fractalkine is a transmembrane protein and chemokine involved in the adhesion and migration of leukocytes. The protein encoded by this gene is a receptor for fractalkine. The encoded protein also is a coreceptor for HIV-1, and some variations in this gene lead to increased susceptibility to HIV-1 infection and rapid progression to AIDS. Four transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Jan 2010]. |
Disorder MIM: | |
Disorder Html: | {Rapid progression to AIDS from HIV1 infection}, 609423 (3); {Coronary artery disease, resistance to}, 607339 (3); {Macular degeneration, age-related, 12}, 613784 (3) |