CCDC50 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	CCDC50
Entrez Gene ID	152137
Full Name	coiled-coil domain containing 50
Synonyms	C3orf6,DFNA44,YMER
General protein information	Preferred Names coiled-coil domain containing 50 Names coiled-coil domain-containing protein 50 protein Ymer
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 3 Map Location: 3q28
Summary	This gene encodes a soluble, cytoplasmic, tyrosine-phosphorylated protein with multiple ubiquitin-interacting domains. Mutations in this gene cause nonsyndromic, postlingual, progressive sensorineural DFNA44 hearing loss. In mouse, the protein is expressed in the inner ear during development and postnatal maturation and associates with microtubule-based structures. This protein may also function as a negative regulator of NF-kB signaling and as an effector of epidermal growth factor (EGF)-mediated cell signaling. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Oct 2008].
Disorder MIM:	611051
Disorder Html:	?Deafness, autosomal dominant 44, 607453 (3)

mRNA and Protein(s)

mRNA	Protein	Name
NM_178335.3	NP_848018.1	coiled-coil domain-containing protein 50 long isoform
NM_174908.4	NP_777568.1	coiled-coil domain-containing protein 50 short isoform
NM_174908.3	NP_777568.1	coiled-coil domain-containing protein 50 short isoform
XM_011512460.1	XP_011510762.1	coiled-coil domain-containing protein 50 isoform X1
NM_178335.2	NP_848018.1	coiled-coil domain-containing protein 50 long isoform

Pathways from BioSystems

Homologies

Canis lupus familiaris (dog)	CCDC50	XP_535844.3
	CCDC50	XP_001094644.2
Gallus gallus (chicken)	CCDC50	NP_001026486.1
Homo sapiens (human)	CCDC50	NP_848018.1
Pan troglodytes (chimpanzee)	CCDC50	XP_516951.3

Gene Ontology
Bibliography

Related articles in PubMed

Research progress in pathogenic genes of hereditary non-syndromic mid-frequency deafness.
Xia W, Liu F, Ma D
Frontiers of medicine10(2)137-42(2016 Jun)

GWAS of cerebrospinal fluid tau levels identifies risk variants for Alzheimer's disease.
Cruchaga C, Kauwe JS, Harari O, Jin SC, Cai Y, Karch CM, Benitez BA, Jeng AT, Skorupa T, Carrell D, Bertelsen S, Bailey M, McKean D, Shulman JM, De Jager PL, Chibnik L, Bennett DA, Arnold SE, Harold D, Sims R, Gerrish A, Williams J, Van Deerlin VM, Lee VM, Shaw LM, Trojanowski JQ, Haines JL, Mayeux R, Pericak-Vance MA, Farrer LA, Schellenberg GD, Peskind ER, Galasko D, Fagan AM, Holtzman DM, Morris JC, , , , Goate AM
Neuron78(2)256-68(2013 Apr)

The E3 ubiquitin ligases RNF126 and Rabring7 regulate endosomal sorting of the epidermal growth factor receptor.
Smith CJ, Berry DM, McGlade CJ
Journal of cell science126(Pt 6)1366-80(2013 Mar)

Ymer acts as a multifunctional regulator in nuclear factor-?B and Fas signaling pathways.
Tsukiyama T, Matsuda-Tsukiyama M, Bohgaki M, Terai S, Tanaka S, Hatakeyama S
Molecular medicine (Cambridge, Mass.)18587-97(2012 May)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Up to now, merely 7 loci have been linked to mid-frequency hearing loss. Only four genetic mid-frequency deafness genes, namely, DFNA10 (EYA4), DFNA8/12 (TECTA), DFNA13 (COL11A2), DFNA44 (CCDC50), have been reported to date. [review]
Title: Research progress in pathogenic genes of hereditary non-syndromic mid-frequency deafness.

Ymer acts as a regulator downstream of several receptors and that Ymer functions as a positive or negative regulator in a signaling pathway-dependent manner.
Title: Ymer acts as a multifunctional regulator in nuclear factor-?B and Fas signaling pathways.

CCDC50 is required for survival in mantle cell lymphoma and chronic lymphocytic leukemia cells and controls NFkappaB signaling
Title: Gene knockdown studies revealed CCDC50 as a candidate gene in mantle cell lymphoma and chronic lymphocytic leukemia.

These findings demonstrate that Ymer is likely to be a negative regulator for the NF-kappaB signaling pathway.
Title: Inhibition of NF-kappaB signaling via tyrosine phosphorylation of Ymer.

Ymer functions as a novel inhibitor for the down-regulation of the EGF receptor and plays a crucial role for regulating the amount of the EGF receptor on the cell surface membrane
Title: Suppression of the ligand-mediated down-regulation of epidermal growth factor receptor by Ymer, a novel tyrosine-phosphorylated and ubiquitinated protein.

The following CCDC50 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the CCDC50 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu26211	NM_174908.4 Latest version!	Homo sapiens coiled-coil domain containing 50 (CCDC50), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$154.50-$216.30 $309.00
OHu26276	NM_178335.3 Latest version!	Homo sapiens coiled-coil domain containing 50 (CCDC50), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$223.30 $319.00
OHu76712	XM_011512460.1 Latest version!	Homo sapiens coiled-coil domain containing 50 (CCDC50), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$139.30 $199.00
View Old Accession Versions >>
OHu26211	NM_174908.3	Homo sapiens coiled-coil domain containing 50 (CCDC50), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$154.50-$216.30 $309.00
OHu26276	NM_178335.2	Homo sapiens coiled-coil domain containing 50 (CCDC50), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$223.30 $319.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

CCDC50 ( NM_174908.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_777568.1 Homo sapiens coiled-coil domain containing 50 (CCDC50), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu26211
Clone ID Related Accession (Same CDS sequence)	NM_174908.4 , NM_174908.3
Accession Version	NM_174908.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 921bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2020-01-03
Organism	Homo sapiens(human)
Product	coiled-coil domain-containing protein 50 short isoform
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AJ416916.2 and AC073365.14. On Jun 1, 2019 this sequence version replaced NM_174908.3. Transcript Variant: This variant (1) lacks an in-frame exon in the coding region, compared to variant 2, and encodes the short isoform. Sequence Note: The RefSeq transcript and protein were derived from transcript and genomic sequence to make the sequence consistent with the reference genome assembly. The extent of this transcript is supported by transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1660803.201568.1, SRR1660805.121978.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGCTGAAG TCAGCATCGA CCAGTCCAAG CTGCCTGGAG TCAAGGAAGT ATGCCGAGAT 
TTTGCTGTCC TGGAGGACCA CACCCTGGCT CACAGCCTGC AGGAACAAGA GATTGAGCAT 
CATTTGGCAT CGAACGTTCA GCGGAACCGT TTGGTCCAGC ATGATCTCCA GGTGGCTAAG 
CAGCTCCAAG AGGAAGATCT GAAAGCGCAG GCCCAGCTCC AGAAGCGCTA CAAAGACCTT 
GAACAACAAG ACTGTGAAAT TGCTCAGGAA ATTCAGGAGA AGCTGGCTAT TGAGGCAGAG 
AGACGACGCA TTCAGGAGAA GAAGGATGAG GACATAGCTC GCCTTTTGCA AGAAAAGGAG 
TTACAGGAAG AGAAAAAGAG AAAGAAACAC TTTCCAGAGT TCCCTGCAAC CCGTGCTTAT 
GCAGATAGTT ACTATTATGA AGATGGAGGA ATGAAGCCAA GAGTGATGAA AGAAGCTGTA 
TCTACTCCAT CACGAATGGC CCACAGGGAT CAGGAATGGT ATGATGCTGA AATTGCCAGA 
AAACTGCAAG AAGAAGAACT TTTGGCTACC CAGGTGGACA TGAGAGCCGC TCAAGTAGCT 
CAAGATGAAG AAATCGCTCG ACTTCTAATG GCTGAAGAAA AGAAAGCTTA CAAAAAAGCC 
AAGGAGCGGG AGAAATCATC TTTGGACAAA AGAAAGCAAG ACCCCGAGTG GAAGCCAAAA 
ACAGCTAAAG CAGCAAATTC CAAGTCAAAA GAGAGTGATG AACCTCACCA TTCTAAGAAT 
GAAAGGCCAG CACGGCCACC ACCACCTATC ATGACAGATG GTGAAGATGC GGATTACACT 
CATTTTACAA ACCAGCAGAG TTCCACACGG CATTTCTCAA AATCAGAGTC CTCTCATAAA 
GGTTTTCATT ACAAACATTA A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_777568.1
CDS	282..1202
Translation	MAEVSIDQSKLPGVKEVCRDFAVLEDHTLAHSLQEQEIEHHLASNVQRNRLVQHDLQVAKQLQEEDLKAQAQLQKRYKDLEQQDCEIAQEIQEKLAIEAERRRIQEKKDEDIARLLQEKELQEEKKRKKHFPEFPATRAYADSYYYEDGGMKPRVMKEAVSTPSRMAHRDQEWYDAEIARKLQEEELLATQVDMRAAQVAQDEEIARLLMAEEKKAYKKAKEREKSSLDKRKQDPEWKPKTAKAANSKSKESDEPHHSKNERPARPPPPIMTDGEDADYTHFTNQQSSTRHFSKSESSHKGFHYKH

Target ORF information:

RefSeq Version	NM_174908.4
Organism	Homo sapiens(human)
Definition	Homo sapiens coiled-coil domain containing 50 (CCDC50), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_174908.4

ORF Insert Sequence:

ATGGCTGAAG TCAGCATCGA CCAGTCCAAG CTGCCTGGAG TCAAGGAAGT ATGCCGAGAT 
TTTGCTGTCC TGGAGGACCA CACCCTGGCT CACAGCCTGC AGGAACAAGA GATTGAGCAT 
CATTTGGCAT CGAACGTTCA GCGGAACCGT TTGGTCCAGC ATGATCTCCA GGTGGCTAAG 
CAGCTCCAAG AGGAAGATCT GAAAGCGCAG GCCCAGCTCC AGAAGCGCTA CAAAGACCTT 
GAACAACAAG ACTGTGAAAT TGCTCAGGAA ATTCAGGAGA AGCTGGCTAT TGAGGCAGAG 
AGACGACGCA TTCAGGAGAA GAAGGATGAG GACATAGCTC GCCTTTTGCA AGAAAAGGAG 
TTACAGGAAG AGAAAAAGAG AAAGAAACAC TTTCCAGAGT TCCCTGCAAC CCGTGCTTAT 
GCAGATAGTT ACTATTATGA AGATGGAGGA ATGAAGCCAA GAGTGATGAA AGAAGCTGTA 
TCTACTCCAT CACGAATGGC CCACAGGGAT CAGGAATGGT ATGATGCTGA AATTGCCAGA 
AAACTGCAAG AAGAAGAACT TTTGGCTACC CAGGTGGACA TGAGAGCCGC TCAAGTAGCT 
CAAGATGAAG AAATCGCTCG ACTTCTAATG GCTGAAGAAA AGAAAGCTTA CAAAAAAGCC 
AAGGAGCGGG AGAAATCATC TTTGGACAAA AGAAAGCAAG ACCCCGAGTG GAAGCCAAAA 
ACAGCTAAAG CAGCAAATTC CAAGTCAAAA GAGAGTGATG AACCTCACCA TTCTAAGAAT 
GAAAGGCCAG CACGGCCACC ACCACCTATC ATGACAGATG GTGAAGATGC GGATTACACT 
CATTTTACAA ACCAGCAGAG TTCCACACGG CATTTCTCAA AATCAGAGTC CTCTCATAAA 
GGTTTTCATT ACAAACATTA A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

CCDC50 ( NM_174908.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_777568.1 Homo sapiens coiled-coil domain containing 50 (CCDC50), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu26211
Clone ID Related Accession (Same CDS sequence)	NM_174908.4 , NM_174908.3
Accession Version	NM_174908.3	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 921bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-02-17
Organism	Homo sapiens(human)
Product	coiled-coil domain-containing protein 50 short isoform
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AJ416916.2 and AC073365.14. On Sep 13, 2008 this sequence version replaced NM_174908.2. Transcript Variant: This variant (1) lacks an in-frame exon in the coding region, compared to variant 2, and encodes the short isoform. Sequence Note: The RefSeq transcript and protein were derived from transcript and genomic sequence to make the sequence consistent with the reference genome assembly. The extent of this transcript is supported by transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AJ416916.2, SRR1660803.201568.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGCTGAAG TCAGCATCGA CCAGTCCAAG CTGCCTGGAG TCAAGGAAGT ATGCCGAGAT 
TTTGCTGTCC TGGAGGACCA CACCCTGGCT CACAGCCTGC AGGAACAAGA GATTGAGCAT 
CATTTGGCAT CGAACGTTCA GCGGAACCGT TTGGTCCAGC ATGATCTCCA GGTGGCTAAG 
CAGCTCCAAG AGGAAGATCT GAAAGCGCAG GCCCAGCTCC AGAAGCGCTA CAAAGACCTT 
GAACAACAAG ACTGTGAAAT TGCTCAGGAA ATTCAGGAGA AGCTGGCTAT TGAGGCAGAG 
AGACGACGCA TTCAGGAGAA GAAGGATGAG GACATAGCTC GCCTTTTGCA AGAAAAGGAG 
TTACAGGAAG AGAAAAAGAG AAAGAAACAC TTTCCAGAGT TCCCTGCAAC CCGTGCTTAT 
GCAGATAGTT ACTATTATGA AGATGGAGGA ATGAAGCCAA GAGTGATGAA AGAAGCTGTA 
TCTACTCCAT CACGAATGGC CCACAGGGAT CAGGAATGGT ATGATGCTGA AATTGCCAGA 
AAACTGCAAG AAGAAGAACT TTTGGCTACC CAGGTGGACA TGAGAGCCGC TCAAGTAGCT 
CAAGATGAAG AAATCGCTCG ACTTCTAATG GCTGAAGAAA AGAAAGCTTA CAAAAAAGCC 
AAGGAGCGGG AGAAATCATC TTTGGACAAA AGAAAGCAAG ACCCCGAGTG GAAGCCAAAA 
ACAGCTAAAG CAGCAAATTC CAAGTCAAAA GAGAGTGATG AACCTCACCA TTCTAAGAAT 
GAAAGGCCAG CACGGCCACC ACCACCTATC ATGACAGATG GTGAAGATGC GGATTACACT 
CATTTTACAA ACCAGCAGAG TTCCACACGG CATTTCTCAA AATCAGAGTC CTCTCATAAA 
GGTTTTCATT ACAAACATTA A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_777568.1
CDS	591..1511
Translation	MAEVSIDQSKLPGVKEVCRDFAVLEDHTLAHSLQEQEIEHHLASNVQRNRLVQHDLQVAKQLQEEDLKAQAQLQKRYKDLEQQDCEIAQEIQEKLAIEAERRRIQEKKDEDIARLLQEKELQEEKKRKKHFPEFPATRAYADSYYYEDGGMKPRVMKEAVSTPSRMAHRDQEWYDAEIARKLQEEELLATQVDMRAAQVAQDEEIARLLMAEEKKAYKKAKEREKSSLDKRKQDPEWKPKTAKAANSKSKESDEPHHSKNERPARPPPPIMTDGEDADYTHFTNQQSSTRHFSKSESSHKGFHYKH

Target ORF information:

RefSeq Version	NM_174908.3
Organism	Homo sapiens(human)
Definition	Homo sapiens coiled-coil domain containing 50 (CCDC50), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_174908.3

ORF Insert Sequence:

ATGGCTGAAG TCAGCATCGA CCAGTCCAAG CTGCCTGGAG TCAAGGAAGT ATGCCGAGAT 
TTTGCTGTCC TGGAGGACCA CACCCTGGCT CACAGCCTGC AGGAACAAGA GATTGAGCAT 
CATTTGGCAT CGAACGTTCA GCGGAACCGT TTGGTCCAGC ATGATCTCCA GGTGGCTAAG 
CAGCTCCAAG AGGAAGATCT GAAAGCGCAG GCCCAGCTCC AGAAGCGCTA CAAAGACCTT 
GAACAACAAG ACTGTGAAAT TGCTCAGGAA ATTCAGGAGA AGCTGGCTAT TGAGGCAGAG 
AGACGACGCA TTCAGGAGAA GAAGGATGAG GACATAGCTC GCCTTTTGCA AGAAAAGGAG 
TTACAGGAAG AGAAAAAGAG AAAGAAACAC TTTCCAGAGT TCCCTGCAAC CCGTGCTTAT 
GCAGATAGTT ACTATTATGA AGATGGAGGA ATGAAGCCAA GAGTGATGAA AGAAGCTGTA 
TCTACTCCAT CACGAATGGC CCACAGGGAT CAGGAATGGT ATGATGCTGA AATTGCCAGA 
AAACTGCAAG AAGAAGAACT TTTGGCTACC CAGGTGGACA TGAGAGCCGC TCAAGTAGCT 
CAAGATGAAG AAATCGCTCG ACTTCTAATG GCTGAAGAAA AGAAAGCTTA CAAAAAAGCC 
AAGGAGCGGG AGAAATCATC TTTGGACAAA AGAAAGCAAG ACCCCGAGTG GAAGCCAAAA 
ACAGCTAAAG CAGCAAATTC CAAGTCAAAA GAGAGTGATG AACCTCACCA TTCTAAGAAT 
GAAAGGCCAG CACGGCCACC ACCACCTATC ATGACAGATG GTGAAGATGC GGATTACACT 
CATTTTACAA ACCAGCAGAG TTCCACACGG CATTTCTCAA AATCAGAGTC CTCTCATAAA 
GGTTTTCATT ACAAACATTA A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

CCDC50 ( NM_178335.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_848018.1 Homo sapiens coiled-coil domain containing 50 (CCDC50), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu26276
Clone ID Related Accession (Same CDS sequence)	NM_178335.3 , NM_178335.2
Accession Version	NM_178335.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1449bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-08-14
Organism	Homo sapiens(human)
Product	coiled-coil domain-containing protein 50 long isoform
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AJ557013.1 and AC073365.14. This sequence is a reference standard in the RefSeqGene project. On Nov 23, 2018 this sequence version replaced NM_178335.2. Transcript Variant: This variant (2) represents the longer transcript and encodes the long isoform. Sequence Note: The RefSeq transcript and protein were derived from transcript and genomic sequence to make the sequence consistent with the reference genome assembly. The extent of this transcript is supported by transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1803612.214301.1, AJ557013.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1968189 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000392455.9/ ENSP00000376249.4 RefSeq Select criteria :: based on conservation, longest protein ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGGCTGAAG TCAGCATCGA CCAGTCCAAG CTGCCTGGAG TCAAGGAAGT ATGCCGAGAT 
TTTGCTGTCC TGGAGGACCA CACCCTGGCT CACAGCCTGC AGGAACAAGA GATTGAGCAT 
CATTTGGCAT CGAACGTTCA GCGGAACCGT TTGGTCCAGC ATGATCTCCA GGTGGCTAAG 
CAGCTCCAAG AGGAAGATCT GAAAGCGCAG GCCCAGCTCC AGAAGCGCTA CAAAGACCTT 
GAACAACAAG ACTGTGAAAT TGCTCAGGAA ATTCAGGAGA AGCTGGCTAT TGAGGCAGAG 
AGACGACGCA TTCAGGAGAA GAAGGATGAG GACATAGCTC GCCTTTTGCA AGAAAAGGAG 
TTACAGGAAG AGAAAAAGAG AAAGAAACAC TTTCCAGAGT TCCCTGCAAC CCGTGCTTAT 
GCAGATAGTT ACTATTATGA AGATGGAGAC CAACCAGGGT CAAGGAGGGC CAGGGAATTG 
GGTTCTGGAT TCTCAAGACC TTGTAGACTC CAAAGAGATG GAAAGACTGT GAAGCACAAG 
AAAGAGAAAC CAGAACATCC ACTGGAGAAC TTGGAAGAGC CAGAACAACA TTGTTCATCG 
AAGAGATCCC TGTCATCCTC TAGCTCGGGC AAAGGGAGGG ACAATCCCCA TATTAACAAT 
GAGCAGCATG AAAGGAAACG GTCCACTCAG GAGAGGCCTC GGAGACCTCT GCTTCCCACG 
ATCAGTGGTG AAGTGTTTCT GAGCACTGAA TGTGATGACT GGGAGACTAA GATTAACCAT 
CAGACTCGAA ATTGGGAAAA ACAGTCTCGA CACCAAGATC GACTTTCACC CAAGTCCTCA 
CAAAAAGCAG GGCTTCACTG CAAGGAAGTT GTATATGGGA GGGACCATGG GCAAGGTGAG 
CACAGAAAAA GGAGACACAG GCCCAGGACT CCTCCATTCT CAGAGAGTGA GGAGCAGCTC 
CACCTCCATG ACGCAGGAAT GAAGCCAAGA GTGATGAAAG AAGCTGTATC TACTCCATCA 
CGAATGGCCC ACAGGGATCA GGAATGGTAT GATGCTGAAA TTGCCAGAAA ACTGCAAGAA 
GAAGAACTTT TGGCTACCCA GGTGGACATG AGAGCCGCTC AAGTAGCTCA AGATGAAGAA 
ATCGCTCGAC TTCTAATGGC TGAAGAAAAG AAAGCTTACA AAAAAGCCAA GGAGCGGGAG 
AAATCATCTT TGGACAAAAG AAAGCAAGAC CCCGAGTGGA AGCCAAAAAC AGCTAAAGCA 
GCAAATTCCA AGTCAAAAGA GAGTGATGAA CCTCACCATT CTAAGAATGA AAGGCCAGCA 
CGGCCACCAC CACCTATCAT GACAGATGGT GAAGATGCGG ATTACACTCA TTTTACAAAC 
CAGCAGAGTT CCACACGGCA TTTCTCAAAA TCAGAGTCCT CTCATAAAGG TTTTCATTAC 
AAACATTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_848018.1
CDS	282..1730
Translation	MAEVSIDQSKLPGVKEVCRDFAVLEDHTLAHSLQEQEIEHHLASNVQRNRLVQHDLQVAKQLQEEDLKAQAQLQKRYKDLEQQDCEIAQEIQEKLAIEAERRRIQEKKDEDIARLLQEKELQEEKKRKKHFPEFPATRAYADSYYYEDGDQPGSRRARELGSGFSRPCRLQRDGKTVKHKKEKPEHPLENLEEPEQHCSSKRSLSSSSSGKGRDNPHINNEQHERKRSTQERPRRPLLPTISGEVFLSTECDDWETKINHQTRNWEKQSRHQDRLSPKSSQKAGLHCKEVVYGRDHGQGEHRKRRHRPRTPPFSESEEQLHLHDAGMKPRVMKEAVSTPSRMAHRDQEWYDAEIARKLQEEELLATQVDMRAAQVAQDEEIARLLMAEEKKAYKKAKEREKSSLDKRKQDPEWKPKTAKAANSKSKESDEPHHSKNERPARPPPPIMTDGEDADYTHFTNQQSSTRHFSKSESSHKGFHYKH

Target ORF information:

RefSeq Version	NM_178335.3
Organism	Homo sapiens(human)
Definition	Homo sapiens coiled-coil domain containing 50 (CCDC50), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_178335.3

ORF Insert Sequence:

ATGGCTGAAG TCAGCATCGA CCAGTCCAAG CTGCCTGGAG TCAAGGAAGT ATGCCGAGAT 
TTTGCTGTCC TGGAGGACCA CACCCTGGCT CACAGCCTGC AGGAACAAGA GATTGAGCAT 
CATTTGGCAT CGAACGTTCA GCGGAACCGT TTGGTCCAGC ATGATCTCCA GGTGGCTAAG 
CAGCTCCAAG AGGAAGATCT GAAAGCGCAG GCCCAGCTCC AGAAGCGCTA CAAAGACCTT 
GAACAACAAG ACTGTGAAAT TGCTCAGGAA ATTCAGGAGA AGCTGGCTAT TGAGGCAGAG 
AGACGACGCA TTCAGGAGAA GAAGGATGAG GACATAGCTC GCCTTTTGCA AGAAAAGGAG 
TTACAGGAAG AGAAAAAGAG AAAGAAACAC TTTCCAGAGT TCCCTGCAAC CCGTGCTTAT 
GCAGATAGTT ACTATTATGA AGATGGAGAC CAACCAGGGT CAAGGAGGGC CAGGGAATTG 
GGTTCTGGAT TCTCAAGACC TTGTAGACTC CAAAGAGATG GAAAGACTGT GAAGCACAAG 
AAAGAGAAAC CAGAACATCC ACTGGAGAAC TTGGAAGAGC CAGAACAACA TTGTTCATCG 
AAGAGATCCC TGTCATCCTC TAGCTCGGGC AAAGGGAGGG ACAATCCCCA TATTAACAAT 
GAGCAGCATG AAAGGAAACG GTCCACTCAG GAGAGGCCTC GGAGACCTCT GCTTCCCACG 
ATCAGTGGTG AAGTGTTTCT GAGCACTGAA TGTGATGACT GGGAGACTAA GATTAACCAT 
CAGACTCGAA ATTGGGAAAA ACAGTCTCGA CACCAAGATC GACTTTCACC CAAGTCCTCA 
CAAAAAGCAG GGCTTCACTG CAAGGAAGTT GTATATGGGA GGGACCATGG GCAAGGTGAG 
CACAGAAAAA GGAGACACAG GCCCAGGACT CCTCCATTCT CAGAGAGTGA GGAGCAGCTC 
CACCTCCATG ACGCAGGAAT GAAGCCAAGA GTGATGAAAG AAGCTGTATC TACTCCATCA 
CGAATGGCCC ACAGGGATCA GGAATGGTAT GATGCTGAAA TTGCCAGAAA ACTGCAAGAA 
GAAGAACTTT TGGCTACCCA GGTGGACATG AGAGCCGCTC AAGTAGCTCA AGATGAAGAA 
ATCGCTCGAC TTCTAATGGC TGAAGAAAAG AAAGCTTACA AAAAAGCCAA GGAGCGGGAG 
AAATCATCTT TGGACAAAAG AAAGCAAGAC CCCGAGTGGA AGCCAAAAAC AGCTAAAGCA 
GCAAATTCCA AGTCAAAAGA GAGTGATGAA CCTCACCATT CTAAGAATGA AAGGCCAGCA 
CGGCCACCAC CACCTATCAT GACAGATGGT GAAGATGCGG ATTACACTCA TTTTACAAAC 
CAGCAGAGTT CCACACGGCA TTTCTCAAAA TCAGAGTCCT CTCATAAAGG TTTTCATTAC 
AAACATTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

CCDC50 ( NM_178335.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_848018.1 Homo sapiens coiled-coil domain containing 50 (CCDC50), transcript variant 2, mRNA.

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CloneID	OHu26276
Clone ID Related Accession (Same CDS sequence)	NM_178335.3 , NM_178335.2
Accession Version	NM_178335.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1449bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-10-01
Organism	Homo sapiens(human)
Product	coiled-coil domain-containing protein 50 long isoform
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AJ557013.1 and AC073365.14. This sequence is a reference standard in the RefSeqGene project. On Sep 13, 2008 this sequence version replaced NM_178335.1. Transcript Variant: This variant (2) represents the longer transcript and encodes the long isoform. Sequence Note: The RefSeq transcript and protein were derived from transcript and genomic sequence to make the sequence consistent with the reference genome assembly. The extent of this transcript is supported by transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AJ557013.1, SRR1803612.214301.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1968189 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGCTGAAG TCAGCATCGA CCAGTCCAAG CTGCCTGGAG TCAAGGAAGT ATGCCGAGAT 
TTTGCTGTCC TGGAGGACCA CACCCTGGCT CACAGCCTGC AGGAACAAGA GATTGAGCAT 
CATTTGGCAT CGAACGTTCA GCGGAACCGT TTGGTCCAGC ATGATCTCCA GGTGGCTAAG 
CAGCTCCAAG AGGAAGATCT GAAAGCGCAG GCCCAGCTCC AGAAGCGCTA CAAAGACCTT 
GAACAACAAG ACTGTGAAAT TGCTCAGGAA ATTCAGGAGA AGCTGGCTAT TGAGGCAGAG 
AGACGACGCA TTCAGGAGAA GAAGGATGAG GACATAGCTC GCCTTTTGCA AGAAAAGGAG 
TTACAGGAAG AGAAAAAGAG AAAGAAACAC TTTCCAGAGT TCCCTGCAAC CCGTGCTTAT 
GCAGATAGTT ACTATTATGA AGATGGAGAC CAACCAGGGT CAAGGAGGGC CAGGGAATTG 
GGTTCTGGAT TCTCAAGACC TTGTAGACTC CAAAGAGATG GAAAGACTGT GAAGCACAAG 
AAAGAGAAAC CAGAACATCC ACTGGAGAAC TTGGAAGAGC CAGAACAACA TTGTTCATCG 
AAGAGATCCC TGTCATCCTC TAGCTCGGGC AAAGGGAGGG ACAATCCCCA TATTAACAAT 
GAGCAGCATG AAAGGAAACG GTCCACTCAG GAGAGGCCTC GGAGACCTCT GCTTCCCACG 
ATCAGTGGTG AAGTGTTTCT GAGCACTGAA TGTGATGACT GGGAGACTAA GATTAACCAT 
CAGACTCGAA ATTGGGAAAA ACAGTCTCGA CACCAAGATC GACTTTCACC CAAGTCCTCA 
CAAAAAGCAG GGCTTCACTG CAAGGAAGTT GTATATGGGA GGGACCATGG GCAAGGTGAG 
CACAGAAAAA GGAGACACAG GCCCAGGACT CCTCCATTCT CAGAGAGTGA GGAGCAGCTC 
CACCTCCATG ACGCAGGAAT GAAGCCAAGA GTGATGAAAG AAGCTGTATC TACTCCATCA 
CGAATGGCCC ACAGGGATCA GGAATGGTAT GATGCTGAAA TTGCCAGAAA ACTGCAAGAA 
GAAGAACTTT TGGCTACCCA GGTGGACATG AGAGCCGCTC AAGTAGCTCA AGATGAAGAA 
ATCGCTCGAC TTCTAATGGC TGAAGAAAAG AAAGCTTACA AAAAAGCCAA GGAGCGGGAG 
AAATCATCTT TGGACAAAAG AAAGCAAGAC CCCGAGTGGA AGCCAAAAAC AGCTAAAGCA 
GCAAATTCCA AGTCAAAAGA GAGTGATGAA CCTCACCATT CTAAGAATGA AAGGCCAGCA 
CGGCCACCAC CACCTATCAT GACAGATGGT GAAGATGCGG ATTACACTCA TTTTACAAAC 
CAGCAGAGTT CCACACGGCA TTTCTCAAAA TCAGAGTCCT CTCATAAAGG TTTTCATTAC 
AAACATTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_848018.1
CDS	591..2039
Translation	MAEVSIDQSKLPGVKEVCRDFAVLEDHTLAHSLQEQEIEHHLASNVQRNRLVQHDLQVAKQLQEEDLKAQAQLQKRYKDLEQQDCEIAQEIQEKLAIEAERRRIQEKKDEDIARLLQEKELQEEKKRKKHFPEFPATRAYADSYYYEDGDQPGSRRARELGSGFSRPCRLQRDGKTVKHKKEKPEHPLENLEEPEQHCSSKRSLSSSSSGKGRDNPHINNEQHERKRSTQERPRRPLLPTISGEVFLSTECDDWETKINHQTRNWEKQSRHQDRLSPKSSQKAGLHCKEVVYGRDHGQGEHRKRRHRPRTPPFSESEEQLHLHDAGMKPRVMKEAVSTPSRMAHRDQEWYDAEIARKLQEEELLATQVDMRAAQVAQDEEIARLLMAEEKKAYKKAKEREKSSLDKRKQDPEWKPKTAKAANSKSKESDEPHHSKNERPARPPPPIMTDGEDADYTHFTNQQSSTRHFSKSESSHKGFHYKH

Target ORF information:

RefSeq Version	NM_178335.2
Organism	Homo sapiens(human)
Definition	Homo sapiens coiled-coil domain containing 50 (CCDC50), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_178335.2

ORF Insert Sequence:

ATGGCTGAAG TCAGCATCGA CCAGTCCAAG CTGCCTGGAG TCAAGGAAGT ATGCCGAGAT 
TTTGCTGTCC TGGAGGACCA CACCCTGGCT CACAGCCTGC AGGAACAAGA GATTGAGCAT 
CATTTGGCAT CGAACGTTCA GCGGAACCGT TTGGTCCAGC ATGATCTCCA GGTGGCTAAG 
CAGCTCCAAG AGGAAGATCT GAAAGCGCAG GCCCAGCTCC AGAAGCGCTA CAAAGACCTT 
GAACAACAAG ACTGTGAAAT TGCTCAGGAA ATTCAGGAGA AGCTGGCTAT TGAGGCAGAG 
AGACGACGCA TTCAGGAGAA GAAGGATGAG GACATAGCTC GCCTTTTGCA AGAAAAGGAG 
TTACAGGAAG AGAAAAAGAG AAAGAAACAC TTTCCAGAGT TCCCTGCAAC CCGTGCTTAT 
GCAGATAGTT ACTATTATGA AGATGGAGAC CAACCAGGGT CAAGGAGGGC CAGGGAATTG 
GGTTCTGGAT TCTCAAGACC TTGTAGACTC CAAAGAGATG GAAAGACTGT GAAGCACAAG 
AAAGAGAAAC CAGAACATCC ACTGGAGAAC TTGGAAGAGC CAGAACAACA TTGTTCATCG 
AAGAGATCCC TGTCATCCTC TAGCTCGGGC AAAGGGAGGG ACAATCCCCA TATTAACAAT 
GAGCAGCATG AAAGGAAACG GTCCACTCAG GAGAGGCCTC GGAGACCTCT GCTTCCCACG 
ATCAGTGGTG AAGTGTTTCT GAGCACTGAA TGTGATGACT GGGAGACTAA GATTAACCAT 
CAGACTCGAA ATTGGGAAAA ACAGTCTCGA CACCAAGATC GACTTTCACC CAAGTCCTCA 
CAAAAAGCAG GGCTTCACTG CAAGGAAGTT GTATATGGGA GGGACCATGG GCAAGGTGAG 
CACAGAAAAA GGAGACACAG GCCCAGGACT CCTCCATTCT CAGAGAGTGA GGAGCAGCTC 
CACCTCCATG ACGCAGGAAT GAAGCCAAGA GTGATGAAAG AAGCTGTATC TACTCCATCA 
CGAATGGCCC ACAGGGATCA GGAATGGTAT GATGCTGAAA TTGCCAGAAA ACTGCAAGAA 
GAAGAACTTT TGGCTACCCA GGTGGACATG AGAGCCGCTC AAGTAGCTCA AGATGAAGAA 
ATCGCTCGAC TTCTAATGGC TGAAGAAAAG AAAGCTTACA AAAAAGCCAA GGAGCGGGAG 
AAATCATCTT TGGACAAAAG AAAGCAAGAC CCCGAGTGGA AGCCAAAAAC AGCTAAAGCA 
GCAAATTCCA AGTCAAAAGA GAGTGATGAA CCTCACCATT CTAAGAATGA AAGGCCAGCA 
CGGCCACCAC CACCTATCAT GACAGATGGT GAAGATGCGG ATTACACTCA TTTTACAAAC 
CAGCAGAGTT CCACACGGCA TTTCTCAAAA TCAGAGTCCT CTCATAAAGG TTTTCATTAC 
AAACATTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

CCDC50 ( XM_011512460.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_011510762.1 Homo sapiens coiled-coil domain containing 50 (CCDC50), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OHu76712
Clone ID Related Accession (Same CDS sequence)	XM_011512460.1
Accession Version	XM_011512460.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 990bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	coiled-coil domain-containing protein 50 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000003.12) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGCTGAAG TCAGCATCGA CCAGTCCAAG CTGCCTGGAG TCAAGGAAGT ATGCCGAGAT 
TTTGCTGTCC TGGAGGACCA CACCCTGGCT CACAGCCTGC AGGAACAAGA GATTGAGCAT 
CATTTGGCAT CGAACGTTCA GCGGAACCGT TTGGTCCAGC ATGATCTCCA GGTGGCTAAG 
CAGCTCCAAG AGGAAGATCT GAAAGCGCAG GCCCAGCTCC AGAAGCGCTA CAAAGACCTT 
GAACAACAAG ACTGTGAAAT TGCTCAGGAA ATTCAGGAGA AGCTGGCTAT TGAGGCAGAG 
AGACGACGCA TTCAGGAGAA GAAGGATGAG GACATAGCTC GCCTTTTGCA AGAAAAGGAG 
TTACAGGAAG AGAAAAAGAG AAAGAAACAC TTTCCAGAGT TCCCTGCAAC CCGTGCTTAT 
GCAGATAGTT ACTATTATGA AGATGGAGAC CAACCAGGGT CAAGGAGGGC CAGGGAATTG 
GGTTCTGGAT TCTCAAGACC TTGTAGACTC CAAAGAGATG GAAAGACTGT GAAGCACAAG 
AAAGAGAAAC CAGAACATCC ACTGGAGAAC TTGGAAGAGC CAGAACAACA TTGTTCATCG 
AAGAGATCCC TGTCATCCTC TAGCTCGGGC AAAGGGAGGG ACAATCCCCA TATTAACAAT 
GAGCAGCATG AAAGGAAACG GTCCACTCAG GAGAGGCCTC GGAGACCTCT GCTTCCCACG 
ATCAGTGGTG AAGTGTTTCT GAGCACTGAA TGTGATGACT GGGAGACTAA GATTAACCAT 
CAGACTCGAA ATTGGGAAAA ACAGTCTCGA CACCAAGATC GACTTTCACC CAAGTCCTCA 
CAAAAAGCAG GGCTTCACTG CAAGGAAGTT GTATATGGGA GGGACCATGG GCAAGGTGAG 
CACAGAAAAA GGAGACACAG GCCCAGGACT CCTCCATTCT CAGAGAGTGA GGAGCAGCTC 
CACCTCCATG ACGCAGGTAT TATCACATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_011510762.1
CDS	594..1583
Translation	MAEVSIDQSKLPGVKEVCRDFAVLEDHTLAHSLQEQEIEHHLASNVQRNRLVQHDLQVAKQLQEEDLKAQAQLQKRYKDLEQQDCEIAQEIQEKLAIEAERRRIQEKKDEDIARLLQEKELQEEKKRKKHFPEFPATRAYADSYYYEDGDQPGSRRARELGSGFSRPCRLQRDGKTVKHKKEKPEHPLENLEEPEQHCSSKRSLSSSSSGKGRDNPHINNEQHERKRSTQERPRRPLLPTISGEVFLSTECDDWETKINHQTRNWEKQSRHQDRLSPKSSQKAGLHCKEVVYGRDHGQGEHRKRRHRPRTPPFSESEEQLHLHDAGIIT

Target ORF information:

RefSeq Version	XM_011512460.1
Organism	Homo sapiens(human)
Definition	Homo sapiens coiled-coil domain containing 50 (CCDC50), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011512460.1

ORF Insert Sequence:

ATGGCTGAAG TCAGCATCGA CCAGTCCAAG CTGCCTGGAG TCAAGGAAGT ATGCCGAGAT 
TTTGCTGTCC TGGAGGACCA CACCCTGGCT CACAGCCTGC AGGAACAAGA GATTGAGCAT 
CATTTGGCAT CGAACGTTCA GCGGAACCGT TTGGTCCAGC ATGATCTCCA GGTGGCTAAG 
CAGCTCCAAG AGGAAGATCT GAAAGCGCAG GCCCAGCTCC AGAAGCGCTA CAAAGACCTT 
GAACAACAAG ACTGTGAAAT TGCTCAGGAA ATTCAGGAGA AGCTGGCTAT TGAGGCAGAG 
AGACGACGCA TTCAGGAGAA GAAGGATGAG GACATAGCTC GCCTTTTGCA AGAAAAGGAG 
TTACAGGAAG AGAAAAAGAG AAAGAAACAC TTTCCAGAGT TCCCTGCAAC CCGTGCTTAT 
GCAGATAGTT ACTATTATGA AGATGGAGAC CAACCAGGGT CAAGGAGGGC CAGGGAATTG 
GGTTCTGGAT TCTCAAGACC TTGTAGACTC CAAAGAGATG GAAAGACTGT GAAGCACAAG 
AAAGAGAAAC CAGAACATCC ACTGGAGAAC TTGGAAGAGC CAGAACAACA TTGTTCATCG 
AAGAGATCCC TGTCATCCTC TAGCTCGGGC AAAGGGAGGG ACAATCCCCA TATTAACAAT 
GAGCAGCATG AAAGGAAACG GTCCACTCAG GAGAGGCCTC GGAGACCTCT GCTTCCCACG 
ATCAGTGGTG AAGTGTTTCT GAGCACTGAA TGTGATGACT GGGAGACTAA GATTAACCAT 
CAGACTCGAA ATTGGGAAAA ACAGTCTCGA CACCAAGATC GACTTTCACC CAAGTCCTCA 
CAAAAAGCAG GGCTTCACTG CAAGGAAGTT GTATATGGGA GGGACCATGG GCAAGGTGAG 
CACAGAAAAA GGAGACACAG GCCCAGGACT CCTCCATTCT CAGAGAGTGA GGAGCAGCTC 
CACCTCCATG ACGCAGGTAT TATCACATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Research progress in pathogenic genes of hereditary non-syndromic mid-frequency deafness.
Frontiers of medicine10(2)137-42(2016 Jun)
Xia W,Liu F,Ma D

GWAS of cerebrospinal fluid tau levels identifies risk variants for Alzheimer's disease.
Neuron78(2)256-68(2013 Apr)
Cruchaga C,Kauwe JS,Harari O,Jin SC,Cai Y,Karch CM,Benitez BA,Jeng AT,Skorupa T,Carrell D,Bertelsen S,Bailey M,McKean D,Shulman JM,De Jager PL,Chibnik L,Bennett DA,Arnold SE,Harold D,Sims R,Gerrish A,Williams J,Van Deerlin VM,Lee VM,Shaw LM,Trojanowski JQ,Haines JL,Mayeux R,Pericak-Vance MA,Farrer LA,Schellenberg GD,Peskind ER,Galasko D,Fagan AM,Holtzman DM,Morris JC,,,,Goate AM

The E3 ubiquitin ligases RNF126 and Rabring7 regulate endosomal sorting of the epidermal growth factor receptor.
Journal of cell science126(Pt 6)1366-80(2013 Mar)
Smith CJ,Berry DM,McGlade CJ

Ymer acts as a multifunctional regulator in nuclear factor-?B and Fas signaling pathways.
Molecular medicine (Cambridge, Mass.)18587-97(2012 May)
Tsukiyama T,Matsuda-Tsukiyama M,Bohgaki M,Terai S,Tanaka S,Hatakeyama S

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CCDC50 cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

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Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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