CTSW cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	CTSW
Entrez Gene ID	1521
Full Name	cathepsin W
Synonyms	LYPN
General protein information	Preferred Names cathepsin W Names cathepsin W lymphopain
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 11 Map Location: 11q13.1
Summary	The protein encoded by this gene, a member of the peptidase C1 family, is a cysteine proteinase that may have a specific function in the mechanism or regulation of T-cell cytolytic activity. The encoded protein is found associated with the membrane inside the endoplasmic reticulum of natural killer and cytotoxic T-cells. Expression of this gene is up-regulated by interleukin-2. [provided by RefSeq, Jul 2008].
Disorder MIM:	602364

mRNA and Protein(s)

mRNA	Protein	Name
NM_001335.3	NP_001326.2	cathepsin W preproprotein
NM_001335.4	NP_001326.3	cathepsin W preproprotein

Pathways from BioSystems

Homologies

Pan troglodytes (chimpanzee)	CTSW	XP_001170363.1
	CTSW	XP_001112560.1
Canis lupus familiaris (dog)	CTSW	XP_540846.2
Xenopus tropicalis (tropical clawed frog)	ctsw	NP_001039033.1
Homo sapiens (human)	CTSW	NP_001326.2
Mus musculus (house mouse)	Ctsw	NP_034115.2
Rattus norvegicus (Norway rat)	Ctsw	NP_001019413.1

Gene Ontology
Bibliography

Related articles in PubMed

Cathepsin W Is Required for Escape of Influenza A Virus from Late Endosomes.
Edinger TO, Pohl MO, Y?ng?ez E, Stertz S
mBio6(3)e00297(2015 Jun)

Genome-wide association study identifies three novel susceptibility loci for severe Acne vulgaris.
Navarini AA, Simpson MA, Weale M, Knight J, Carlavan I, Reiniche P, Burden DA, Layton A, Bataille V, Allen M, Pleass R, Pink A, Creamer D, English J, Munn S, Walton S, , Willis C, D?ret S, Voegel JJ, Spector T, Smith CH, Trembath RC, Barker JN
Nature communications54020(2014 Jun)

Host-microbe interactions have shaped the genetic architecture of inflammatory bowel disease.
Jostins L, Ripke S, Weersma RK, Duerr RH, McGovern DP, Hui KY, Lee JC, Schumm LP, Sharma Y, Anderson CA, Essers J, Mitrovic M, Ning K, Cleynen I, Theatre E, Spain SL, Raychaudhuri S, Goyette P, Wei Z, Abraham C, Achkar JP, Ahmad T, Amininejad L, Ananthakrishnan AN, Andersen V, Andrews JM, Baidoo L, Balschun T, Bampton PA, Bitton A, Boucher G, Brand S, B?ning C, Cohain A, Cichon S, D'Amato M, De Jong D, Devaney KL, Dubinsky M, Edwards C, Ellinghaus D, Ferguson LR, Franchimont D, Fransen K, Gearry R, Georges M, Gieger C, Glas J, Haritunians T, Hart A, Hawkey C, Hedl M, Hu X, Karlsen TH, Kupcinskas L, Kugathasan S, Latiano A, Laukens D, Lawrance IC, Lees CW, Louis E, Mahy G, Mansfield J, Morgan AR, Mowat C, Newman W, Palmieri O, Ponsioen CY, Potocnik U, Prescott NJ, Regueiro M, Rotter JI, Russell RK, Sanderson JD, Sans M, Satsangi J, Schreiber S, Simms LA, Sventoraityte J, Targan SR, Taylor KD, Tremelling M, Verspaget HW, De Vos M, Wijmenga C, Wilson DC, Winkelmann J, Xavier RJ, Zeissig S, Zhang B, Zhang CK, Zhao H, , Silverberg MS, Annese V, Hakonarson H, Brant SR, Radford-Smith G, Mathew CG, Rioux JD, Schadt EE, Daly MJ, Franke A, Parkes M, Vermeire S, Barrett JC, Cho JH
Nature491(7422)119-24(2012 Nov)

Expression pattern of cathepsin W isoforms in peripheral blood and gastroesophageal mucosa of patients with gastroesophageal reflux disease.
Raab AK, M?nkem?ller K, Kandulski A, Weber E, Malfertheiner P, Wex T
Biological chemistry392(12)1167-72(2011 Dec)

Defining the membrane proteome of NK cells.
Ghosh D, Lippert D, Krokhin O, Cortens JP, Wilkins JA
Journal of mass spectrometry : JMS45(1)1-25(2010 Jan)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

These results establish CtsW as an important host factor for entry of influenza A virus into target cells and suggest that CtsW could be a promising target for the development of future antiviral drugs.
Title: Cathepsin W Is Required for Escape of Influenza A Virus from Late Endosomes.

The predominant expression of wildtype form by infiltrating immune cells was confirmed in 116 patients with gastroesophageal reflux disease and 27 reflux-negative individuals demonstrating that cathepsin W expression is not altered in this disease.
Title: Expression pattern of cathepsin W isoforms in peripheral blood and gastroesophageal mucosa of patients with gastroesophageal reflux disease.

Despite being expressed in the effector subset of CD8(+) and NK cells and of being released during target cell killing, our functional inhibition studies exclude an essential role of CatW in the process of cytotoxicity.
Title: Cathepsin W expressed exclusively in CD8+ T cells and NK cells, is secreted during target cell killing but is not essential for cytotoxicity in human CTLs.

a genetic variant and a novel isoform of cathepsin W are present in about 14% and 12%, respectively, within the Caucasian population
Title: Identification of a novel isoform predominantly expressed in gastric tissue and a triple-base pair polymorphism of the cathepsin W gene.

Cathepsin W-positive cells had a 'lymphocyte phenotype', but the relative portion of cathepsin W-positive cells among the infiltrating leukocytes in gastrointestinal disease differed remarkably.
Title: Characterization of novel anti-cathepsin W antibodies and cellular distribution of cathepsin W in the gastrointestinal tract.

The following CTSW gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the CTSW cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OHu30143	NM_001335.3 Latest version!	Homo sapiens cathepsin W (CTSW), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$189.50-$265.30 $379.00
OHu107212	NM_001335.4 Latest version!	Homo sapiens cathepsin W (CTSW), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$223.30 $319.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

CTSW ( NM_001335.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_001326.2 Homo sapiens cathepsin W (CTSW), mRNA.

Price & Availability↑

CloneID	OHu30143
Clone ID Related Accession (Same CDS sequence)	NM_001335.3
Accession Version	NM_001335.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1131bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-10-01
Organism	Homo sapiens(human)
Product	cathepsin W preproprotein
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BC048255.1 and BC035637.1. On Dec 14, 2006 this sequence version replaced NM_001335.2. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC048255.1, ERR279827.6790.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGCACTGA CTGCCCACCC CTCCTGCCTC CTGGCCCTGT TGGTGGCAGG CCTAGCCCAA 
GGCATCAGAG GCCCCCTTAG GGCCCAGGAC CTAGGTCCCC AGCCGCTAGA GCTGAAAGAG 
GCCTTCAAGT TGTTCCAGAT CCAGTTCAAC CGGAGTTACC TGAGCCCAGA AGAGCATGCT 
CACCGCCTGG ACATCTTTGC CCACAACCTG GCCCAGGCTC AGAGGCTGCA GGAGGAGGAC 
TTGGGCACAG CTGAGTTTGG GGTGACTCCA TTCAGTGACC TCACAGAGGA GGAGTTTGGC 
CAGCTCTATG GCTATCGGAG GGCAGCTGGA GGGGTCCCCA GCATGGGCAG AGAAATAAGG 
TCTGAAGAGC CAGAGGAGTC AGTACCTTTC AGCTGTGACT GGCGGAAGGT GGCCGGCGCC 
ATCTCACCCA TCAAGGACCA GAAAAACTGC AACTGCTGCT GGGCCATGGC AGCGGCAGGC 
AACATAGAGA CCCTGTGGCG CATCAGTTTC TGGGATTTTG TGGACGTCTC CGTGCAGGAA 
CTGCTGGACT GTGGCCGCTG TGGGGATGGC TGCCACGGTG GCTTCGTCTG GGACGCGTTC 
ATAACTGTCC TCAACAACAG CGGCCTGGCC AGTGAAAAGG ACTACCCGTT CCAGGGCAAA 
GTCAGAGCCC ACAGGTGCCA CCCCAAGAAG TACCAGAAGG TGGCCTGGAT CCAGGACTTC 
ATCATGCTGC AGAACAACGA GCACAGAATT GCGCAGTACC TGGCCACTTA TGGCCCCATC 
ACCGTGACCA TCAACATGAA GCCCCTTCAG CTATACCGGA AAGGTGTGAT CAAGGCCACA 
CCCACCACCT GTGACCCCCA GCTTGTGGAC CACTCTGTCC TGCTGGTGGG TTTTGGCAGC 
GTCAAGTCAG AGGAGGGGAT ATGGGCAGAG ACAGTCTCAT CGCAGTCTCA GCCTCAGCCT 
CCACACCCCA CCCCATACTG GATCCTGAAG AACTCCTGGG GGGCCCAATG GGGAGAGAAG 
GGCTATTTCC GGCTGCACCG AGGGAGCAAT ACCTGTGGCA TCACCAAGTT CCCGCTCACT 
GCCCGTGTGC AGAAACCGGA TATGAAGCCC CGAGTCTCCT GCCCTCCCTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001326.2
CDS	43..1173
Translation	MALTAHPSCLLALLVAGLAQGIRGPLRAQDLGPQPLELKEAFKLFQIQFNRSYLSPEEHAHRLDIFAHNLAQAQRLQEEDLGTAEFGVTPFSDLTEEEFGQLYGYRRAAGGVPSMGREIRSEEPEESVPFSCDWRKVAGAISPIKDQKNCNCCWAMAAAGNIETLWRISFWDFVDVSVQELLDCGRCGDGCHGGFVWDAFITVLNNSGLASEKDYPFQGKVRAHRCHPKKYQKVAWIQDFIMLQNNEHRIAQYLATYGPITVTINMKPLQLYRKGVIKATPTTCDPQLVDHSVLLVGFGSVKSEEGIWAETVSSQSQPQPPHPTPYWILKNSWGAQWGEKGYFRLHRGSNTCGITKFPLTARVQKPDMKPRVSCPP

Target ORF information:

RefSeq Version	NM_001335.3
Organism	Homo sapiens(human)
Definition	Homo sapiens cathepsin W (CTSW), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001335.3

ORF Insert Sequence:

ATGGCACTGA CTGCCCACCC CTCCTGCCTC CTGGCCCTGT TGGTGGCAGG CCTAGCCCAA 
GGCATCAGAG GCCCCCTTAG GGCCCAGGAC CTAGGTCCCC AGCCGCTAGA GCTGAAAGAG 
GCCTTCAAGT TGTTCCAGAT CCAGTTCAAC CGGAGTTACC TGAGCCCAGA AGAGCATGCT 
CACCGCCTGG ACATCTTTGC CCACAACCTG GCCCAGGCTC AGAGGCTGCA GGAGGAGGAC 
TTGGGCACAG CTGAGTTTGG GGTGACTCCA TTCAGTGACC TCACAGAGGA GGAGTTTGGC 
CAGCTCTATG GCTATCGGAG GGCAGCTGGA GGGGTCCCCA GCATGGGCAG AGAAATAAGG 
TCTGAAGAGC CAGAGGAGTC AGTACCTTTC AGCTGTGACT GGCGGAAGGT GGCCGGCGCC 
ATCTCACCCA TCAAGGACCA GAAAAACTGC AACTGCTGCT GGGCCATGGC AGCGGCAGGC 
AACATAGAGA CCCTGTGGCG CATCAGTTTC TGGGATTTTG TGGACGTCTC CGTGCAGGAA 
CTGCTGGACT GTGGCCGCTG TGGGGATGGC TGCCACGGTG GCTTCGTCTG GGACGCGTTC 
ATAACTGTCC TCAACAACAG CGGCCTGGCC AGTGAAAAGG ACTACCCGTT CCAGGGCAAA 
GTCAGAGCCC ACAGGTGCCA CCCCAAGAAG TACCAGAAGG TGGCCTGGAT CCAGGACTTC 
ATCATGCTGC AGAACAACGA GCACAGAATT GCGCAGTACC TGGCCACTTA TGGCCCCATC 
ACCGTGACCA TCAACATGAA GCCCCTTCAG CTATACCGGA AAGGTGTGAT CAAGGCCACA 
CCCACCACCT GTGACCCCCA GCTTGTGGAC CACTCTGTCC TGCTGGTGGG TTTTGGCAGC 
GTCAAGTCAG AGGAGGGGAT ATGGGCAGAG ACAGTCTCAT CGCAGTCTCA GCCTCAGCCT 
CCACACCCCA CCCCATACTG GATCCTGAAG AACTCCTGGG GGGCCCAATG GGGAGAGAAG 
GGCTATTTCC GGCTGCACCG AGGGAGCAAT ACCTGTGGCA TCACCAAGTT CCCGCTCACT 
GCCCGTGTGC AGAAACCGGA TATGAAGCCC CGAGTCTCCT GCCCTCCCTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

CTSW ( NM_001335.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_001326.3 Homo sapiens cathepsin W (CTSW), mRNA.

Price & Availability↑

CloneID	OHu107212
Clone ID Related Accession (Same CDS sequence)	NM_001335.4
Accession Version	NM_001335.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1131bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-29
Organism	Homo sapiens(human)
Product	cathepsin W preproprotein
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AP001201.7. On Nov 22, 2018 this sequence version replaced NM_001335.3. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC035637.1, BC048255.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000307886.8/ ENSP00000311300.3 RefSeq Select criteria :: based on single protein-coding transcript ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGGCACTGA CTGCCCACCC CTCCTGCCTC CTGGCCCTGT TGGTGGCAGG CCTAGCCCAA 
GGCATCAGAG GCCCCCTTAG GGCCCAGGAC CTAGGTCCCC AGCCGCTAGA GCTGAAAGAG 
GCCTTCAAGT TGTTCCAGAT CCAGTTCAAC CGGAGTTACC TGAGCCCAGA AGAGCATGCT 
CACCGCCTGG ACATCTTTGC CCACAACCTG GCCCAGGCTC AGAGGCTGCA GGAGGAGGAC 
TTGGGCACAG CTGAGTTTGG GGTGACTCCA TTCAGTGACC TCACAGAGGA GGAGTTTGGC 
CAGCTCTATG GCTATCGGAG GGCAGCTGGA GGGGTCCCCA GCATGGGCAG AGAAATAAGG 
TCTGAAGAGC CAGAGGAGTC AGTACCTTTC AGCTGTGACT GGCGGAAGGT GGCCAGCGCC 
ATCTCACCCA TCAAGGACCA GAAAAACTGC AACTGCTGCT GGGCCATGGC AGCGGCAGGC 
AACATAGAGA CCCTGTGGCG CATCAGTTTC TGGGATTTTG TGGATGTCTC CGTGCAGGAA 
CTGCTGGACT GTGGCCGCTG TGGGGATGGC TGCCACGGTG GCTTCGTCTG GGACGCGTTC 
ATAACTGTCC TCAACAACAG CGGCCTGGCC AGTGAAAAGG ACTACCCGTT CCAGGGCAAA 
GTCAGAGCCC ACAGGTGCCA CCCCAAGAAG TACCAGAAGG TGGCCTGGAT CCAGGACTTC 
ATCATGCTGC AGAACAACGA GCACAGAATT GCGCAGTACC TGGCCACTTA TGGCCCCATC 
ACCGTGACCA TCAACATGAA GCCCCTTCAG CTATACCGGA AAGGTGTGAT CAAGGCCACA 
CCCACCACCT GTGACCCCCA GCTTGTGGAC CACTCTGTCC TGCTGGTGGG TTTTGGCAGC 
GTCAAGTCAG AGGAGGGGAT ATGGGCAGAG ACAGTCTCAT CGCAGTCTCA GCCTCAGCCT 
CCACACCCCA CCCCATACTG GATCCTGAAG AACTCCTGGG GGGCCCAATG GGGAGAGAAG 
GGCTATTTCC GGCTGCACCG AGGGAGCAAT ACCTGTGGCA TCACCAAGTT CCCGCTCACT 
GCCCGTGTGC AGAAACCGGA TATGAAGCCC CGAGTCTCCT GCCCTCCCTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001326.3
CDS	19..1149
Translation	MALTAHPSCLLALLVAGLAQGIRGPLRAQDLGPQPLELKEAFKLFQIQFNRSYLSPEEHAHRLDIFAHNLAQAQRLQEEDLGTAEFGVTPFSDLTEEEFGQLYGYRRAAGGVPSMGREIRSEEPEESVPFSCDWRKVASAISPIKDQKNCNCCWAMAAAGNIETLWRISFWDFVDVSVQELLDCGRCGDGCHGGFVWDAFITVLNNSGLASEKDYPFQGKVRAHRCHPKKYQKVAWIQDFIMLQNNEHRIAQYLATYGPITVTINMKPLQLYRKGVIKATPTTCDPQLVDHSVLLVGFGSVKSEEGIWAETVSSQSQPQPPHPTPYWILKNSWGAQWGEKGYFRLHRGSNTCGITKFPLTARVQKPDMKPRVSCPP

Target ORF information:

RefSeq Version	NM_001335.4
Organism	Homo sapiens(human)
Definition	Homo sapiens cathepsin W (CTSW), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001335.4

ORF Insert Sequence:

ATGGCACTGA CTGCCCACCC CTCCTGCCTC CTGGCCCTGT TGGTGGCAGG CCTAGCCCAA 
GGCATCAGAG GCCCCCTTAG GGCCCAGGAC CTAGGTCCCC AGCCGCTAGA GCTGAAAGAG 
GCCTTCAAGT TGTTCCAGAT CCAGTTCAAC CGGAGTTACC TGAGCCCAGA AGAGCATGCT 
CACCGCCTGG ACATCTTTGC CCACAACCTG GCCCAGGCTC AGAGGCTGCA GGAGGAGGAC 
TTGGGCACAG CTGAGTTTGG GGTGACTCCA TTCAGTGACC TCACAGAGGA GGAGTTTGGC 
CAGCTCTATG GCTATCGGAG GGCAGCTGGA GGGGTCCCCA GCATGGGCAG AGAAATAAGG 
TCTGAAGAGC CAGAGGAGTC AGTACCTTTC AGCTGTGACT GGCGGAAGGT GGCCAGCGCC 
ATCTCACCCA TCAAGGACCA GAAAAACTGC AACTGCTGCT GGGCCATGGC AGCGGCAGGC 
AACATAGAGA CCCTGTGGCG CATCAGTTTC TGGGATTTTG TGGATGTCTC CGTGCAGGAA 
CTGCTGGACT GTGGCCGCTG TGGGGATGGC TGCCACGGTG GCTTCGTCTG GGACGCGTTC 
ATAACTGTCC TCAACAACAG CGGCCTGGCC AGTGAAAAGG ACTACCCGTT CCAGGGCAAA 
GTCAGAGCCC ACAGGTGCCA CCCCAAGAAG TACCAGAAGG TGGCCTGGAT CCAGGACTTC 
ATCATGCTGC AGAACAACGA GCACAGAATT GCGCAGTACC TGGCCACTTA TGGCCCCATC 
ACCGTGACCA TCAACATGAA GCCCCTTCAG CTATACCGGA AAGGTGTGAT CAAGGCCACA 
CCCACCACCT GTGACCCCCA GCTTGTGGAC CACTCTGTCC TGCTGGTGGG TTTTGGCAGC 
GTCAAGTCAG AGGAGGGGAT ATGGGCAGAG ACAGTCTCAT CGCAGTCTCA GCCTCAGCCT 
CCACACCCCA CCCCATACTG GATCCTGAAG AACTCCTGGG GGGCCCAATG GGGAGAGAAG 
GGCTATTTCC GGCTGCACCG AGGGAGCAAT ACCTGTGGCA TCACCAAGTT CCCGCTCACT 
GCCCGTGTGC AGAAACCGGA TATGAAGCCC CGAGTCTCCT GCCCTCCCTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Cathepsin W Is Required for Escape of Influenza A Virus from Late Endosomes.
mBio6(3)e00297(2015 Jun)
Edinger TO,Pohl MO,Y?ng?ez E,Stertz S

Genome-wide association study identifies three novel susceptibility loci for severe Acne vulgaris.
Nature communications54020(2014 Jun)
Navarini AA,Simpson MA,Weale M,Knight J,Carlavan I,Reiniche P,Burden DA,Layton A,Bataille V,Allen M,Pleass R,Pink A,Creamer D,English J,Munn S,Walton S,,Willis C,D?ret S,Voegel JJ,Spector T,Smith CH,Trembath RC,Barker JN

Host-microbe interactions have shaped the genetic architecture of inflammatory bowel disease.
Nature491(7422)119-24(2012 Nov)
Jostins L,Ripke S,Weersma RK,Duerr RH,McGovern DP,Hui KY,Lee JC,Schumm LP,Sharma Y,Anderson CA,Essers J,Mitrovic M,Ning K,Cleynen I,Theatre E,Spain SL,Raychaudhuri S,Goyette P,Wei Z,Abraham C,Achkar JP,Ahmad T,Amininejad L,Ananthakrishnan AN,Andersen V,Andrews JM,Baidoo L,Balschun T,Bampton PA,Bitton A,Boucher G,Brand S,B?ning C,Cohain A,Cichon S,D'Amato M,De Jong D,Devaney KL,Dubinsky M,Edwards C,Ellinghaus D,Ferguson LR,Franchimont D,Fransen K,Gearry R,Georges M,Gieger C,Glas J,Haritunians T,Hart A,Hawkey C,Hedl M,Hu X,Karlsen TH,Kupcinskas L,Kugathasan S,Latiano A,Laukens D,Lawrance IC,Lees CW,Louis E,Mahy G,Mansfield J,Morgan AR,Mowat C,Newman W,Palmieri O,Ponsioen CY,Potocnik U,Prescott NJ,Regueiro M,Rotter JI,Russell RK,Sanderson JD,Sans M,Satsangi J,Schreiber S,Simms LA,Sventoraityte J,Targan SR,Taylor KD,Tremelling M,Verspaget HW,De Vos M,Wijmenga C,Wilson DC,Winkelmann J,Xavier RJ,Zeissig S,Zhang B,Zhang CK,Zhao H,,Silverberg MS,Annese V,Hakonarson H,Brant SR,Radford-Smith G,Mathew CG,Rioux JD,Schadt EE,Daly MJ,Franke A,Parkes M,Vermeire S,Barrett JC,Cho JH

Expression pattern of cathepsin W isoforms in peripheral blood and gastroesophageal mucosa of patients with gastroesophageal reflux disease.
Biological chemistry392(12)1167-72(2011 Dec)
Raab AK,M?nkem?ller K,Kandulski A,Weber E,Malfertheiner P,Wex T

Defining the membrane proteome of NK cells.
Journal of mass spectrometry : JMS45(1)1-25(2010 Jan)
Ghosh D,Lippert D,Krokhin O,Cortens JP,Wilkins JA

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CTSW cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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