UPP2 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	UPP2
Entrez Gene ID	151531
Full Name	uridine phosphorylase 2
Synonyms	UDRPASE2,UP2,UPASE2
General protein information	Preferred Names uridine phosphorylase 2 Names uridine phosphorylase 2 UPase 2 liver-specific uridine phosphorylase urdPase 2
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 2 Map Location: 2q24.1
Disorder MIM:	617340

mRNA and Protein(s)

mRNA	Protein	Name
NM_173355.3	NP_775491.1	uridine phosphorylase 2 isoform a
XM_005246359.3	XP_005246416.1	uridine phosphorylase 2 isoform X2
NM_001135098.1	NP_001128570.1	uridine phosphorylase 2 isoform b
NM_173355.4	NP_775491.1	uridine phosphorylase 2 isoform a
XM_017003484.1	XP_016858973.1	uridine phosphorylase 2 isoform X1

Pathways from BioSystems

Homologies

Pan troglodytes (chimpanzee)	UPP2	XP_525947.4
Gallus gallus (chicken)	UPP2	XP_422171.2
Xenopus tropicalis (tropical clawed frog)	upp2	NP_001008174.1
Bos taurus (cattle)	UPP2	NP_001069511.1
Rattus norvegicus (Norway rat)	Upp2	NP_001099951.1
	LOC698067	XP_001089251.2
Danio rerio (zebrafish)	upp2	NP_956438.1
Caenorhabditis elegans (roundworm)	upp-1	NP_498671.2
Homo sapiens (human)	UPP2	NP_001128570.1
Mus musculus (house mouse)	Upp2	NP_083968.1
Drosophila melanogaster (fruit fly)	CG6330	NP_651515.1
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP000188	XP_310948.4

Gene Ontology
Bibliography

Related articles in PubMed

Widespread Expansion of Protein Interaction Capabilities by Alternative Splicing.
Yang X, Coulombe-Huntington J, Kang S, Sheynkman GM, Hao T, Richardson A, Sun S, Yang F, Shen YA, Murray RR, Spirohn K, Begg BE, Duran-Frigola M, MacWilliams A, Pevzner SJ, Zhong Q, Trigg SA, Tam S, Ghamsari L, Sahni N, Yi S, Rodriguez MD, Balcha D, Tan G, Costanzo M, Andrews B, Boone C, Zhou XJ, Salehi-Ashtiani K, Charloteaux B, Chen AA, Calderwood MA, Aloy P, Roth FP, Hill DE, Iakoucheva LM, Xia Y, Vidal M
Cell164(4)805-17(2016 Feb)

Allowing for sex differences increases power in a GWAS of multiplex Autism families.
Lu AT, Cantor RM
Molecular psychiatry17(2)215-22(2012 Feb)

A novel structural mechanism for redox regulation of uridine phosphorylase 2 activity.
Roosild TP, Castronovo S, Villoso A, Ziemba A, Pizzorno G
Journal of structural biology176(2)229-37(2011 Nov)

Genome-wide association reveals genetic effects on human A?42 and ? protein levels in cerebrospinal fluids: a case control study.
Han MR, Schellenberg GD, Wang LS,
BMC neurology1090(2010 Oct)

High-density SNP association study and copy number variation analysis of the AUTS1 and AUTS5 loci implicate the IMMP2L-DOCK4 gene region in autism susceptibility.
Maestrini E, Pagnamenta AT, Lamb JA, Bacchelli E, Sykes NH, Sousa I, Toma C, Barnby G, Butler H, Winchester L, Scerri TS, Minopoli F, Reichert J, Cai G, Buxbaum JD, Korvatska O, Schellenberg GD, Dawson G, de Bildt A, Minderaa RB, Mulder EJ, Morris AP, Bailey AJ, Monaco AP,
Molecular psychiatry15(9)954-68(2010 Sep)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

This study demonistrated that use joint test to identified that UPP2 association to Autism Spectrum Disorder.
Title: Allowing for sex differences increases power in a GWAS of multiplex Autism families.

A novel structural mechanism for redox regulation of uridine phosphorylase 2 activity
Title: A novel structural mechanism for redox regulation of uridine phosphorylase 2 activity.

Observational study of gene-disease association. (HuGE Navigator)
Title: High-density SNP association study and copy number variation analysis of the AUTS1 and AUTS5 loci implicate the IMMP2L-DOCK4 gene region in autism susceptibility.

identification of the novel human uridine phosphorylase, UDPase 2, with broad substrate specificity; UPase-2 gene was mapped to chromosome 2q24.1 and the 2.2-kb mRNA was predominantly expressed in kidney
Title: Identification of a novel human uridine phosphorylase.

The following UPP2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the UPP2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu07232	NM_173355.4 Latest version!	Homo sapiens uridine phosphorylase 2 (UPP2), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$154.50-$216.30 $309.00
OHu31604	NM_001135098.1 Latest version!	Homo sapiens uridine phosphorylase 2 (UPP2), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$189.50-$265.30 $379.00
OHu35947	XM_005246359.3 Latest version!	Homo sapiens uridine phosphorylase 2 (UPP2), transcript variant X4, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$139.30 $199.00
OHu89086	XM_017003484.1 Latest version!	Homo sapiens uridine phosphorylase 2 (UPP2), transcript variant X3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$139.30 $199.00
View Old Accession Versions >>
OHu07232	NM_173355.3	Homo sapiens uridine phosphorylase 2 (UPP2), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$154.50-$216.30 $309.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

UPP2 ( NM_173355.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_775491.1 Homo sapiens uridine phosphorylase 2 (UPP2), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu07232
Clone ID Related Accession (Same CDS sequence)	NM_173355.3 , NM_173355.4
Accession Version	NM_173355.3	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 954bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-06-10
Organism	Homo sapiens(human)
Product	uridine phosphorylase 2 isoform a
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AK122743.2, AA995921.1 and AW771260.1. On Sep 20, 2008 this sequence version replaced NM_173355.2. Transcript Variant: This variant (1) represents the longer transcript but encodes the shorter isoform (a). ##Evidence-Data-START## Transcript exon combination :: AK122743.2, AY225131.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1970526, SAMEA2145774 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## RefSeq Select criteria :: based on expression ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGGCTTCAG TTATACCTGC CTCCAATAGG TCCATGAGAT CTGACAGGAA TACATATGTT 
GGAAAAAGGT TTGTTCACGT TAAAAATCCT TACTTGGATT TGATGGATGA AGACATTCTC 
TATCACTTGG ATTTGGGAAC AAAAACACAC AACCTACCAG CAATGTTTGG AGATGTAAAG 
TTTGTCTGTG TCGGTGGGAG CCCCAACAGA ATGAAAGCAT TTGCACTGTT TATGCACAAG 
GAGCTCGGGT TTGAGGAAGC TGAAGAAGAC ATAAAAGACA TCTGTGCTGG GACAGACAGA 
TACTGTATGT ACAAAACCGG GCCTGTGCTC GCCATCAGTC ACGGCATGGG CATCCCCTCC 
ATTTCTATTA TGCTTCATGA ACTCATCAAA TTACTCCACC ATGCACGGTG CTGCGATGTC 
ACCATTATTA GAATCGGTAC ATCAGGGGGA ATAGGGATTG CACCAGGGAC TGTTGTAATA 
ACGGATATAG CTGTAGACTC CTTCTTTAAG CCCCGGTTTG AACAGGTCAT TTTGGACAAC 
ATTGTCACCC GAAGTACTGA ACTGGACAAA GAACTGTCTG AAGAACTGTT CAACTGTAGC 
AAAGAAATCC CCAACTTCCC AACCCTCGTT GGACATACAA TGTGTACCTA TGATTTTTAT 
GAAGGCCAAG GCCGACTAGA TGGAGCACTG TGCTCCTTTT CCAGAGAAAA AAAGTTAGAC 
TACTTGAAGA GAGCATTTAA AGCTGGTGTC AGGAATATTG AAATGGAATC TACAGTGTTT 
GCAGCTATGT GTGGACTCTG TGGTCTAAAA GCTGCTGTGG TCTGTGTGAC ACTTCTCGAC 
AGACTCGACT GTGATCAGAT CAACTTGCCT CATGATGTCC TGGTGGAGTA CCAGCAACGG 
CCTCAGCTCC TAATCTCCAA CTTCATCAGA CGGCGGCTTG GACTTTGTGA CTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_775491.1
CDS	195..1148
Translation	MASVIPASNRSMRSDRNTYVGKRFVHVKNPYLDLMDEDILYHLDLGTKTHNLPAMFGDVKFVCVGGSPNRMKAFALFMHKELGFEEAEEDIKDICAGTDRYCMYKTGPVLAISHGMGIPSISIMLHELIKLLHHARCCDVTIIRIGTSGGIGIAPGTVVITDIAVDSFFKPRFEQVILDNIVTRSTELDKELSEELFNCSKEIPNFPTLVGHTMCTYDFYEGQGRLDGALCSFSREKKLDYLKRAFKAGVRNIEMESTVFAAMCGLCGLKAAVVCVTLLDRLDCDQINLPHDVLVEYQQRPQLLISNFIRRRLGLCD

Target ORF information:

RefSeq Version	NM_173355.3
Organism	Homo sapiens(human)
Definition	Homo sapiens uridine phosphorylase 2 (UPP2), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_173355.3

ORF Insert Sequence:

ATGGCTTCAG TTATACCTGC CTCCAATAGG TCCATGAGAT CTGACAGGAA TACATATGTT 
GGAAAAAGGT TTGTTCACGT TAAAAATCCT TACTTGGATT TGATGGATGA AGACATTCTC 
TATCACTTGG ATTTGGGAAC AAAAACACAC AACCTACCAG CAATGTTTGG AGATGTAAAG 
TTTGTCTGTG TCGGTGGGAG CCCCAACAGA ATGAAAGCAT TTGCACTGTT TATGCACAAG 
GAGCTCGGGT TTGAGGAAGC TGAAGAAGAC ATAAAAGACA TCTGTGCTGG GACAGACAGA 
TACTGTATGT ACAAAACCGG GCCTGTGCTC GCCATCAGTC ACGGCATGGG CATCCCCTCC 
ATTTCTATTA TGCTTCATGA ACTCATCAAA TTACTCCACC ATGCACGGTG CTGCGATGTC 
ACCATTATTA GAATCGGTAC ATCAGGGGGA ATAGGGATTG CACCAGGGAC TGTTGTAATA 
ACGGATATAG CTGTAGACTC CTTCTTTAAG CCCCGGTTTG AACAGGTCAT TTTGGACAAC 
ATTGTCACCC GAAGTACTGA ACTGGACAAA GAACTGTCTG AAGAACTGTT CAACTGTAGC 
AAAGAAATCC CCAACTTCCC AACCCTCGTT GGACATACAA TGTGTACCTA TGATTTTTAT 
GAAGGCCAAG GCCGACTAGA TGGAGCACTG TGCTCCTTTT CCAGAGAAAA AAAGTTAGAC 
TACTTGAAGA GAGCATTTAA AGCTGGTGTC AGGAATATTG AAATGGAATC TACAGTGTTT 
GCAGCTATGT GTGGACTCTG TGGTCTAAAA GCTGCTGTGG TCTGTGTGAC ACTTCTCGAC 
AGACTCGACT GTGATCAGAT CAACTTGCCT CATGATGTCC TGGTGGAGTA CCAGCAACGG 
CCTCAGCTCC TAATCTCCAA CTTCATCAGA CGGCGGCTTG GACTTTGTGA CTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

UPP2 ( NM_173355.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_775491.1 Homo sapiens uridine phosphorylase 2 (UPP2), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu07232
Clone ID Related Accession (Same CDS sequence)	NM_173355.3 , NM_173355.4
Accession Version	NM_173355.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 954bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-11-20
Organism	Homo sapiens(human)
Product	uridine phosphorylase 2 isoform a
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC005539.1. On Nov 21, 2019 this sequence version replaced NM_173355.3. Transcript Variant: This variant (1) represents the longer transcript but encodes the shorter isoform (a). ##Evidence-Data-START## Transcript exon combination :: AK122743.2, AY225131.1 [ECO:0000332] ##Evidence-Data-END## ##RefSeq-Attributes-START## RefSeq Select criteria :: based on expression ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGGCTTCAG TTATACCTGC CTCCAATAGG TCCATGAGAT CTGACAGGAA TACATATGTT 
GGAAAAAGGT TTGTTCACGT TAAAAATCCT TACTTGGATT TGATGGATGA AGACATTCTC 
TATCACTTGG ATTTGGGAAC AAAAACACAC AACCTACCAG CAATGTTTGG AGATGTAAAG 
TTTGTCTGTG TCGGTGGGAG CCCCAACAGA ATGAAAGCAT TTGCACTGTT TATGCACAAG 
GAGCTCGGGT TTGAGGAAGC TGAAGAAGAC ATAAAAGACA TCTGTGCTGG GACAGACAGA 
TACTGTATGT ACAAAACCGG GCCTGTGCTC GCCATCAGTC ACGGCATGGG CATCCCCTCC 
ATTTCTATTA TGCTTCATGA ACTCATCAAA TTACTCCACC ATGCACGGTG CTGCGATGTC 
ACCATTATTA GAATCGGTAC ATCAGGGGGA ATAGGGATTG CACCAGGGAC TGTTGTAATA 
ACGGATATAG CTGTAGACTC CTTCTTTAAG CCCCGGTTTG AACAGGTCAT TTTGGACAAC 
ATTGTCACCC GAAGTACTGA ACTGGACAAA GAACTGTCTG AAGAACTGTT CAACTGTAGC 
AAAGAAATCC CCAACTTCCC AACCCTCGTT GGACATACAA TGTGTACCTA TGATTTTTAT 
GAAGGCCAAG GCCGACTAGA TGGAGCACTG TGCTCCTTTT CCAGAGAAAA AAAGTTAGAC 
TACTTGAAGA GAGCATTTAA AGCTGGTGTC AGGAATATTG AAATGGAATC TACAGTGTTT 
GCAGCTATGT GTGGACTCTG TGGTCTAAAA GCTGCTGTGG TCTGTGTGAC ACTTCTCGAC 
AGACTCGACT GTGATCAGAT CAACTTGCCT CATGATGTCC TGGTGGAGTA CCAGCAACGG 
CCTCAGCTCC TAATCTCCAA CTTCATCAGA CGGCGGCTTG GACTTTGTGA CTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_775491.1
CDS	189..1142
Translation	MASVIPASNRSMRSDRNTYVGKRFVHVKNPYLDLMDEDILYHLDLGTKTHNLPAMFGDVKFVCVGGSPNRMKAFALFMHKELGFEEAEEDIKDICAGTDRYCMYKTGPVLAISHGMGIPSISIMLHELIKLLHHARCCDVTIIRIGTSGGIGIAPGTVVITDIAVDSFFKPRFEQVILDNIVTRSTELDKELSEELFNCSKEIPNFPTLVGHTMCTYDFYEGQGRLDGALCSFSREKKLDYLKRAFKAGVRNIEMESTVFAAMCGLCGLKAAVVCVTLLDRLDCDQINLPHDVLVEYQQRPQLLISNFIRRRLGLCD

Target ORF information:

RefSeq Version	NM_173355.4
Organism	Homo sapiens(human)
Definition	Homo sapiens uridine phosphorylase 2 (UPP2), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_173355.4

ORF Insert Sequence:

ATGGCTTCAG TTATACCTGC CTCCAATAGG TCCATGAGAT CTGACAGGAA TACATATGTT 
GGAAAAAGGT TTGTTCACGT TAAAAATCCT TACTTGGATT TGATGGATGA AGACATTCTC 
TATCACTTGG ATTTGGGAAC AAAAACACAC AACCTACCAG CAATGTTTGG AGATGTAAAG 
TTTGTCTGTG TCGGTGGGAG CCCCAACAGA ATGAAAGCAT TTGCACTGTT TATGCACAAG 
GAGCTCGGGT TTGAGGAAGC TGAAGAAGAC ATAAAAGACA TCTGTGCTGG GACAGACAGA 
TACTGTATGT ACAAAACCGG GCCTGTGCTC GCCATCAGTC ACGGCATGGG CATCCCCTCC 
ATTTCTATTA TGCTTCATGA ACTCATCAAA TTACTCCACC ATGCACGGTG CTGCGATGTC 
ACCATTATTA GAATCGGTAC ATCAGGGGGA ATAGGGATTG CACCAGGGAC TGTTGTAATA 
ACGGATATAG CTGTAGACTC CTTCTTTAAG CCCCGGTTTG AACAGGTCAT TTTGGACAAC 
ATTGTCACCC GAAGTACTGA ACTGGACAAA GAACTGTCTG AAGAACTGTT CAACTGTAGC 
AAAGAAATCC CCAACTTCCC AACCCTCGTT GGACATACAA TGTGTACCTA TGATTTTTAT 
GAAGGCCAAG GCCGACTAGA TGGAGCACTG TGCTCCTTTT CCAGAGAAAA AAAGTTAGAC 
TACTTGAAGA GAGCATTTAA AGCTGGTGTC AGGAATATTG AAATGGAATC TACAGTGTTT 
GCAGCTATGT GTGGACTCTG TGGTCTAAAA GCTGCTGTGG TCTGTGTGAC ACTTCTCGAC 
AGACTCGACT GTGATCAGAT CAACTTGCCT CATGATGTCC TGGTGGAGTA CCAGCAACGG 
CCTCAGCTCC TAATCTCCAA CTTCATCAGA CGGCGGCTTG GACTTTGTGA CTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

UPP2 ( NM_001135098.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001128570.1 Homo sapiens uridine phosphorylase 2 (UPP2), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu31604
Clone ID Related Accession (Same CDS sequence)	NM_001135098.1
Accession Version	NM_001135098.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1125bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-08-02
Organism	Homo sapiens(human)
Product	uridine phosphorylase 2 isoform b
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BC033529.2, AC005539.1 and AW771260.1. Transcript Variant: This variant (2) differs in the 5' UTR and includes two additional exons in the 5' coding region, compared to variant 1. The resulting isoform (b) is longer at the N-terminus, compared to isoform a. ##Evidence-Data-START## Transcript exon combination :: BC033529.2 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA2145313, SAMEA2145743 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGCTGGCCC CAGGCTGTGA GTTGGACCCA GACCAAGAAG TGGTGAGGAC AAGGCCTGAA 
GATGTGCCTG CTTCCCCTTC AACTTCCACC ATGATTGTAA GTGTCCTGAG GCCTCCCAGC 
CATGCTTCCT GTACAGCCTG TGGAACTGTG ACTTTTCACA TAGTAGAGAG AATGGCTTCA 
GTTATACCTG CCTCCAATAG GTCCATGAGA TCTGACAGGA ATACATATGT TGGAAAAAGG 
TTTGTTCACG TTAAAAATCC TTACTTGGAT TTGATGGATG AAGACATTCT CTATCACTTG 
GATTTGGGAA CAAAAACACA CAACCTACCA GCAATGTTTG GAGATGTAAA GTTTGTCTGT 
GTCGGTGGGA GCCCCAACAG AATGAAAGCA TTTGCACTGT TTATGCACAA GGAGCTCGGG 
TTTGAGGAAG CTGAAGAAGA CATAAAAGAC ATCTGTGCTG GGACAGACAG ATACTGTATG 
TACAAAACCG GGCCTGTGCT CGCCATCAGT CACGGCATGG GCATCCCCTC CATTTCTATT 
ATGCTTCATG AACTCATCAA ATTACTCCAC CATGCACGGT GCTGCGATGT CACCATTATT 
AGAATCGGTA CATCAGGGGG AATAGGGATT GCACCAGGGA CTGTTGTAAT AACGGATATA 
GCTGTAGACT CCTTCTTTAA GCCCCGGTTT GAACAGGTCA TTTTGGACAA CATTGTCACC 
CGAAGTACTG AACTGGACAA AGAACTGTCT GAAGAACTGT TCAACTGTAG CAAAGAAATC 
CCCAACTTCC CAACCCTCGT TGGACATACA ATGTGTACCT ATGATTTTTA TGAAGGCCAA 
GGCCGACTAG ATGGAGCACT GTGCTCCTTT TCCAGAGAAA AAAAGTTAGA CTACTTGAAG 
AGAGCATTTA AAGCTGGTGT CAGGAATATT GAAATGGAAT CTACAGTGTT TGCAGCTATG 
TGTGGACTCT GTGGTCTAAA AGCTGCTGTG GTCTGTGTGA CACTTCTCGA CAGACTCGAC 
TGTGATCAGA TCAACTTGCC TCATGATGTC CTGGTGGAGT ACCAGCAACG GCCTCAGCTC 
CTAATCTCCA ACTTCATCAG ACGGCGGCTT GGACTTTGTG ACTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001128570.1
CDS	21..1145
Translation	MLAPGCELDPDQEVVRTRPEDVPASPSTSTMIVSVLRPPSHASCTACGTVTFHIVERMASVIPASNRSMRSDRNTYVGKRFVHVKNPYLDLMDEDILYHLDLGTKTHNLPAMFGDVKFVCVGGSPNRMKAFALFMHKELGFEEAEEDIKDICAGTDRYCMYKTGPVLAISHGMGIPSISIMLHELIKLLHHARCCDVTIIRIGTSGGIGIAPGTVVITDIAVDSFFKPRFEQVILDNIVTRSTELDKELSEELFNCSKEIPNFPTLVGHTMCTYDFYEGQGRLDGALCSFSREKKLDYLKRAFKAGVRNIEMESTVFAAMCGLCGLKAAVVCVTLLDRLDCDQINLPHDVLVEYQQRPQLLISNFIRRRLGLCD

Target ORF information:

RefSeq Version	NM_001135098.1
Organism	Homo sapiens(human)
Definition	Homo sapiens uridine phosphorylase 2 (UPP2), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001135098.1

ORF Insert Sequence:

ATGCTGGCCC CAGGCTGTGA GTTGGACCCA GACCAAGAAG TGGTGAGGAC AAGGCCTGAA 
GATGTGCCTG CTTCCCCTTC AACTTCCACC ATGATTGTAA GTGTCCTGAG GCCTCCCAGC 
CATGCTTCCT GTACAGCCTG TGGAACTGTG ACTTTTCACA TAGTAGAGAG AATGGCTTCA 
GTTATACCTG CCTCCAATAG GTCCATGAGA TCTGACAGGA ATACATATGT TGGAAAAAGG 
TTTGTTCACG TTAAAAATCC TTACTTGGAT TTGATGGATG AAGACATTCT CTATCACTTG 
GATTTGGGAA CAAAAACACA CAACCTACCA GCAATGTTTG GAGATGTAAA GTTTGTCTGT 
GTCGGTGGGA GCCCCAACAG AATGAAAGCA TTTGCACTGT TTATGCACAA GGAGCTCGGG 
TTTGAGGAAG CTGAAGAAGA CATAAAAGAC ATCTGTGCTG GGACAGACAG ATACTGTATG 
TACAAAACCG GGCCTGTGCT CGCCATCAGT CACGGCATGG GCATCCCCTC CATTTCTATT 
ATGCTTCATG AACTCATCAA ATTACTCCAC CATGCACGGT GCTGCGATGT CACCATTATT 
AGAATCGGTA CATCAGGGGG AATAGGGATT GCACCAGGGA CTGTTGTAAT AACGGATATA 
GCTGTAGACT CCTTCTTTAA GCCCCGGTTT GAACAGGTCA TTTTGGACAA CATTGTCACC 
CGAAGTACTG AACTGGACAA AGAACTGTCT GAAGAACTGT TCAACTGTAG CAAAGAAATC 
CCCAACTTCC CAACCCTCGT TGGACATACA ATGTGTACCT ATGATTTTTA TGAAGGCCAA 
GGCCGACTAG ATGGAGCACT GTGCTCCTTT TCCAGAGAAA AAAAGTTAGA CTACTTGAAG 
AGAGCATTTA AAGCTGGTGT CAGGAATATT GAAATGGAAT CTACAGTGTT TGCAGCTATG 
TGTGGACTCT GTGGTCTAAA AGCTGCTGTG GTCTGTGTGA CACTTCTCGA CAGACTCGAC 
TGTGATCAGA TCAACTTGCC TCATGATGTC CTGGTGGAGT ACCAGCAACG GCCTCAGCTC 
CTAATCTCCA ACTTCATCAG ACGGCGGCTT GGACTTTGTG ACTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

UPP2 ( XM_005246359.3 ) cDNA ORF clone, Homo sapiens(human) -> XP_005246416.1 Homo sapiens uridine phosphorylase 2 (UPP2), transcript variant X4, mRNA.

Price & Availability↑

CloneID	OHu35947
Clone ID Related Accession (Same CDS sequence)	XM_005246359.3
Accession Version	XM_005246359.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 846bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	uridine phosphorylase 2 isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000002.12) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 6, 2016 this sequence version replaced XM_005246359.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGCTTCAG TTATACCTGC CTCCAATAGG TCCATGAGAT CTGACAGGAA TACATATGTT 
GGAAAAAGGT TTGTTCACGT TAAAAATCCT TACTTGGATT TGATGGATGA AGACATTCTC 
TATCACTTGG ATTTGGGAAC AAAAACACAC AACCTACCAG CAATGTTTGG AGATGTAAAG 
TTTGTCTGTG TCGGTGGGAG CCCCAACAGA ATGAAAGCAT TTGCACTGTT TATGCACAAG 
GAGCTCGGGT TTGAGGAAGC TGAAGAAGAC ATAAAAGACA TCTGTGCTGG GACAGACAGA 
TACTGTATGT ACAAAACCGG GCCTGTGCTC GCCATCAGTC ACGGCATGGG CATCCCCTCC 
ATTTCTATTA TGCTTCATGA ACTCATCAAA TTACTCCACC ATGCACGGTG CTGCGATGTC 
ACCATTATTA GAATCGGTAC ATCAGGGGGA ATAGGGATTG CACCAGGGAC TGTTGTAATA 
ACGGATATAG CTGTAGACTC CTTCTTTAAG CCCCGGTTTG AACAGGTCAT TTTGGACAAC 
ATTGTCACCC GAAGTACTGA ACTGGACAAA GAACTGTCTG AAGAACTGTT CAACTGTAGC 
AAAGAAATCC CCAACTTCCC AACCCTCGTT GGACATACAA TGTGTACCTA TGATTTTTAT 
GAAGGCCAAG GCCGACTAGA TGGAGCACTG TGCTCCTTTT CCAGAGAAAA AAAGTTAGAC 
TACTTGAAGA GAGCATTTAA AGCTGGTGTC AGGAATATTG AAATGGAATC TACAGTGTTT 
GCAGCTATGT GTGGACTCTG TGGTCTAAAA GCAAAATCTA CTTTAATTAA GCCCCAAACA 
TTCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_005246416.1
CDS	195..1040
Translation	MASVIPASNRSMRSDRNTYVGKRFVHVKNPYLDLMDEDILYHLDLGTKTHNLPAMFGDVKFVCVGGSPNRMKAFALFMHKELGFEEAEEDIKDICAGTDRYCMYKTGPVLAISHGMGIPSISIMLHELIKLLHHARCCDVTIIRIGTSGGIGIAPGTVVITDIAVDSFFKPRFEQVILDNIVTRSTELDKELSEELFNCSKEIPNFPTLVGHTMCTYDFYEGQGRLDGALCSFSREKKLDYLKRAFKAGVRNIEMESTVFAAMCGLCGLKAKSTLIKPQTF

Target ORF information:

RefSeq Version	XM_005246359.3
Organism	Homo sapiens(human)
Definition	Homo sapiens uridine phosphorylase 2 (UPP2), transcript variant X4, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_005246359.3

ORF Insert Sequence:

ATGGCTTCAG TTATACCTGC CTCCAATAGG TCCATGAGAT CTGACAGGAA TACATATGTT 
GGAAAAAGGT TTGTTCACGT TAAAAATCCT TACTTGGATT TGATGGATGA AGACATTCTC 
TATCACTTGG ATTTGGGAAC AAAAACACAC AACCTACCAG CAATGTTTGG AGATGTAAAG 
TTTGTCTGTG TCGGTGGGAG CCCCAACAGA ATGAAAGCAT TTGCACTGTT TATGCACAAG 
GAGCTCGGGT TTGAGGAAGC TGAAGAAGAC ATAAAAGACA TCTGTGCTGG GACAGACAGA 
TACTGTATGT ACAAAACCGG GCCTGTGCTC GCCATCAGTC ACGGCATGGG CATCCCCTCC 
ATTTCTATTA TGCTTCATGA ACTCATCAAA TTACTCCACC ATGCACGGTG CTGCGATGTC 
ACCATTATTA GAATCGGTAC ATCAGGGGGA ATAGGGATTG CACCAGGGAC TGTTGTAATA 
ACGGATATAG CTGTAGACTC CTTCTTTAAG CCCCGGTTTG AACAGGTCAT TTTGGACAAC 
ATTGTCACCC GAAGTACTGA ACTGGACAAA GAACTGTCTG AAGAACTGTT CAACTGTAGC 
AAAGAAATCC CCAACTTCCC AACCCTCGTT GGACATACAA TGTGTACCTA TGATTTTTAT 
GAAGGCCAAG GCCGACTAGA TGGAGCACTG TGCTCCTTTT CCAGAGAAAA AAAGTTAGAC 
TACTTGAAGA GAGCATTTAA AGCTGGTGTC AGGAATATTG AAATGGAATC TACAGTGTTT 
GCAGCTATGT GTGGACTCTG TGGTCTAAAA GCAAAATCTA CTTTAATTAA GCCCCAAACA 
TTCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

UPP2 ( XM_017003484.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_016858973.1 Homo sapiens uridine phosphorylase 2 (UPP2), transcript variant X3, mRNA.

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CloneID	OHu89086
Clone ID Related Accession (Same CDS sequence)	XM_017003484.1
Accession Version	XM_017003484.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 861bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	uridine phosphorylase 2 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000002.12) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGCTTCAG TTATACCTGC CTCCAATAGG TCCATGAGAT CTGACAGGAA TACATATGTT 
GGAAAAAGGT TTGTTCACGT TAAAAATCCT TACTTGGATT TGATGGATGA AGACATTCTC 
TATCACTTGG ATTTGGGAAC AAAAACACAC AACCTACCAG CAATGTTTGG AGATGTAAAG 
TTTGTCTGTG TCGGTGGGAG CCCCAACAGA ATGAAAGCAT TTGCACTGTT TATGCACAAG 
GAGCTCGGGT TTGAGGAAGC TGAAGAAGAC ATAAAAGACA TCTGTGCTGG GACAGACAGA 
TACTGTATGT ACAAAACCGG GCCTGTGCTC GCCATCAGTC ACGGCATGGG CATCCCCTCC 
ATTTCTATTA TGCTTCATGA ACTCATCAAA TTACTCCACC ATGCACGGTG CTGCGATGTC 
ACCATTATTA GAATCGGTAC ATCAGGGGGA ATAGGGATTG CACCAGGGAC TGTTGTAATA 
ACGGATATAG CTGTAGACTC CTTCTTTAAG CCCCGGTTTG AACAGGTCAT TTTGGACAAC 
ATTGTCACCC GAAGTACTGA ACTGGACAAA GAACTGTCTG AAGAACTGTT CAACTGTAGC 
AAAGAAATCC CCAACTTCCC AACCCTCGTT GGACATACAA TGTGTACCTA TGATTTTTAT 
GAAGCACCCA TCCCTGGGCC ATTCCCCAGT CATTGGAGCA ACCTGAGATT TTCCTCAAAG 
GGCAGCTCTC ACAGCAACCC CCCGCTTCCT GATTTCCCTG GGCACAGTGC TGGCTGCTGC 
AGCCACTCAA CAGTTACTGA CCCCAGAACT GAGGTCCTCG GCCATGAAGG CTCCTTCCTA 
CGTATGAGAC TCCTCAGCTA G

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_016858973.1
CDS	195..1055
Translation	MASVIPASNRSMRSDRNTYVGKRFVHVKNPYLDLMDEDILYHLDLGTKTHNLPAMFGDVKFVCVGGSPNRMKAFALFMHKELGFEEAEEDIKDICAGTDRYCMYKTGPVLAISHGMGIPSISIMLHELIKLLHHARCCDVTIIRIGTSGGIGIAPGTVVITDIAVDSFFKPRFEQVILDNIVTRSTELDKELSEELFNCSKEIPNFPTLVGHTMCTYDFYEAPIPGPFPSHWSNLRFSSKGSSHSNPPLPDFPGHSAGCCSHSTVTDPRTEVLGHEGSFLRMRLLS

Target ORF information:

RefSeq Version	XM_017003484.1
Organism	Homo sapiens(human)
Definition	Homo sapiens uridine phosphorylase 2 (UPP2), transcript variant X3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017003484.1

ORF Insert Sequence:

ATGGCTTCAG TTATACCTGC CTCCAATAGG TCCATGAGAT CTGACAGGAA TACATATGTT 
GGAAAAAGGT TTGTTCACGT TAAAAATCCT TACTTGGATT TGATGGATGA AGACATTCTC 
TATCACTTGG ATTTGGGAAC AAAAACACAC AACCTACCAG CAATGTTTGG AGATGTAAAG 
TTTGTCTGTG TCGGTGGGAG CCCCAACAGA ATGAAAGCAT TTGCACTGTT TATGCACAAG 
GAGCTCGGGT TTGAGGAAGC TGAAGAAGAC ATAAAAGACA TCTGTGCTGG GACAGACAGA 
TACTGTATGT ACAAAACCGG GCCTGTGCTC GCCATCAGTC ACGGCATGGG CATCCCCTCC 
ATTTCTATTA TGCTTCATGA ACTCATCAAA TTACTCCACC ATGCACGGTG CTGCGATGTC 
ACCATTATTA GAATCGGTAC ATCAGGGGGA ATAGGGATTG CACCAGGGAC TGTTGTAATA 
ACGGATATAG CTGTAGACTC CTTCTTTAAG CCCCGGTTTG AACAGGTCAT TTTGGACAAC 
ATTGTCACCC GAAGTACTGA ACTGGACAAA GAACTGTCTG AAGAACTGTT CAACTGTAGC 
AAAGAAATCC CCAACTTCCC AACCCTCGTT GGACATACAA TGTGTACCTA TGATTTTTAT 
GAAGCACCCA TCCCTGGGCC ATTCCCCAGT CATTGGAGCA ACCTGAGATT TTCCTCAAAG 
GGCAGCTCTC ACAGCAACCC CCCGCTTCCT GATTTCCCTG GGCACAGTGC TGGCTGCTGC 
AGCCACTCAA CAGTTACTGA CCCCAGAACT GAGGTCCTCG GCCATGAAGG CTCCTTCCTA 
CGTATGAGAC TCCTCAGCTA G

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Widespread Expansion of Protein Interaction Capabilities by Alternative Splicing.
Cell164(4)805-17(2016 Feb)
Yang X,Coulombe-Huntington J,Kang S,Sheynkman GM,Hao T,Richardson A,Sun S,Yang F,Shen YA,Murray RR,Spirohn K,Begg BE,Duran-Frigola M,MacWilliams A,Pevzner SJ,Zhong Q,Trigg SA,Tam S,Ghamsari L,Sahni N,Yi S,Rodriguez MD,Balcha D,Tan G,Costanzo M,Andrews B,Boone C,Zhou XJ,Salehi-Ashtiani K,Charloteaux B,Chen AA,Calderwood MA,Aloy P,Roth FP,Hill DE,Iakoucheva LM,Xia Y,Vidal M

Allowing for sex differences increases power in a GWAS of multiplex Autism families.
Molecular psychiatry17(2)215-22(2012 Feb)
Lu AT,Cantor RM

A novel structural mechanism for redox regulation of uridine phosphorylase 2 activity.
Journal of structural biology176(2)229-37(2011 Nov)
Roosild TP,Castronovo S,Villoso A,Ziemba A,Pizzorno G

Genome-wide association reveals genetic effects on human A?42 and ? protein levels in cerebrospinal fluids: a case control study.
BMC neurology1090(2010 Oct)
Han MR,Schellenberg GD,Wang LS,

High-density SNP association study and copy number variation analysis of the AUTS1 and AUTS5 loci implicate the IMMP2L-DOCK4 gene region in autism susceptibility.
Molecular psychiatry15(9)954-68(2010 Sep)
Maestrini E,Pagnamenta AT,Lamb JA,Bacchelli E,Sykes NH,Sousa I,Toma C,Barnby G,Butler H,Winchester L,Scerri TS,Minopoli F,Reichert J,Cai G,Buxbaum JD,Korvatska O,Schellenberg GD,Dawson G,de Bildt A,Minderaa RB,Mulder EJ,Morris AP,Bailey AJ,Monaco AP,

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UPP2 cDNA ORF clone, Homo sapiens(human)

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Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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見積依頼

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電話

FAX

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