FAM109B cDNA ORF clone, Homo sapiens(Human)

Gene
Clones
gRNAs

Summary

Gene Symbol	FAM109B
Entrez Gene ID	150368
Full Name	family with sequence similarity 109 member B
Synonyms	IPIP27B,Ses2
General protein information	Preferred Names family with sequence similarity 109 member B Names sesquipedalian-2 27 kDa inositol polyphosphate phosphatase interacting protein B inositol polyphosphate phosphatase-interacting protein B
Gene Type	protein-coding
Organism	Homo sapiens(Human)
Genome	Chromosome: 22 Map Location: 22q13.2
Disorder MIM:	614240

mRNA and Protein(s)

mRNA	Protein	Name
XM_005261373.3	XP_005261430.1	sesquipedalian-2 isoform X1
NM_001002034.3	NP_001002034.2	sesquipedalian-2
NM_001002034.2	NP_001002034.2	sesquipedalian-2
XM_005261373.2	XP_005261430.1	sesquipedalian-2 isoform X1

Pathways from BioSystems

Homologies

	FAM109B	XP_001106558.1
Pan troglodytes (chimpanzee)	FAM109B	XP_001154643.2
Canis lupus familiaris (dog)	FAM109B	XP_005625866.1
Bos taurus (cattle)	FAM109B	NP_001039401.2
Mus musculus (house mouse)	Fam109b	NP_796365.1
Homo sapiens (human)	FAM109B	NP_001002034.2
Rattus norvegicus (Norway rat)	Fam109b	NP_001123983.1

Gene Ontology
Bibliography

Related articles in PubMed

Architecture of the human interactome defines protein communities and disease networks.
Huttlin EL, Bruckner RJ, Paulo JA, Cannon JR, Ting L, Baltier K, Colby G, Gebreab F, Gygi MP, Parzen H, Szpyt J, Tam S, Zarraga G, Pontano-Vaites L, Swarup S, White AE, Schweppe DK, Rad R, Erickson BK, Obar RA, Guruharsha KG, Li K, Artavanis-Tsakonas S, Gygi SP, Harper JW
Nature545(7655)505-509(2017 05)

Pooled-matrix protein interaction screens using Barcode Fusion Genetics.
Yachie N, Petsalaki E, Mellor JC, Weile J, Jacob Y, Verby M, Ozturk SB, Li S, Cote AG, Mosca R, Knapp JJ, Ko M, Yu A, Gebbia M, Sahni N, Yi S, Tyagi T, Sheykhkarimli D, Roth JF, Wong C, Musa L, Snider J, Liu YC, Yu H, Braun P, Stagljar I, Hao T, Calderwood MA, Pelletier L, Aloy P, Hill DE, Vidal M, Roth FP
Molecular systems biology12(4)863(2016 Apr)

Biological insights from 108 schizophrenia-associated genetic loci.

Nature511(7510)421-7(2014 Jul)

The PH domain proteins IPIP27A and B link OCRL1 to receptor recycling in the endocytic pathway.
Noakes CJ, Lee G, Lowe M
Molecular biology of the cell22(5)606-23(2011 Mar)

Two closely related endocytic proteins that share a common OCRL-binding motif with APPL1.
Swan LE, Tomasini L, Pirruccello M, Lunardi J, De Camilli P
Proceedings of the National Academy of Sciences of the United States of America107(8)3511-6(2010 Feb)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Two novel OCRL1-binding proteins, termed inositol polyphosphate phosphatase interacting protein of 27 kDa (IPIP27)A and B (also known as Ses1 and 2), that also bind the related 5-phosphatase Inpp5b, were identified.
Title: The PH domain proteins IPIP27A and B link OCRL1 to receptor recycling in the endocytic pathway.

Two closely related endocytic proteins, Ses1 and Ses2, which interact with OCRL, were identified. The interaction is mediated by a short amino acid motif similar to that used by the rab-5 effector APPL1.
Title: Two closely related endocytic proteins that share a common OCRL-binding motif with APPL1.

The following FAM109B gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the FAM109B cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu03387	NM_001002034.3 Latest version!	Homo sapiens PH domain containing endocytic trafficking adaptor 2 (PHETA2), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
OHu03387	XM_005261373.3 Latest version!	Homo sapiens PH domain containing endocytic trafficking adaptor 2 (PHETA2), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
View Old Accession Versions >>
OHu03387	NM_001002034.2	Homo sapiens family with sequence similarity 109 member B (FAM109B), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
OHu03387	XM_005261373.2	Homo sapiens family with sequence similarity 109, member B (FAM109B), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

FAM109B ( NM_001002034.3 ) cDNA ORF clone, Homo sapiens(Human) -> NP_001002034.2 Homo sapiens PH domain containing endocytic trafficking adaptor 2 (PHETA2), mRNA.

Price & Availability↑

CloneID	OHu03387
Clone ID Related Accession (Same CDS sequence)	XM_005261373.3 , NM_001002034.3 , NM_001002034.2 , XM_005261373.2
Accession Version	NM_001002034.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 780bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-10-09
Organism	Homo sapiens(human)
Product	sesquipedalian-2
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from Z99716.4, BX648402.1 and Z82192.1. On Nov 22, 2018 this sequence version replaced NM_001002034.2. ##Evidence-Data-START## Transcript exon combination :: BX648402.1, SRR1660807.30377.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000321753.8/ ENSP00000312753.3 RefSeq Select criteria :: based on conservation, expression, longest protein ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGAAGCTGA ACGAGAGGAG TGTAGCCCAC TATGCACTCA GCGACTCCCC AGCGGACCAC 
ATGGGCTTCC TGCGCACCTG GGGGGGCCCA GGGACCCCAC CGACCCCCAG TGGCACTGGC 
CGAAGATGCT GGTTTGTCCT CAAGGGCAAC CTGCTATTCT CCTTTGAGAG TCGCGAGGGC 
CGGGCCCCAC TGAGCCTGGT GGTGCTGGAA GGCTGCACAG TGGAACTGGC CGAGGCTCCC 
GTGCCCGAGG AGTTTGCCTT TGCCATCTGC TTTGATGCCC CTGGAGTGCG CCCACACCTG 
CTGGCCGCAG AAGGGCCGGC GGCCCAGGAG GCCTGGGTGA AGGTGCTGTC CCGGGCAAGC 
TTTGGCTACA TGCGCCTGGT GGTACGCGAG TTGGAGAGCC AGTTGCAGGA CGCACGCCAG 
AGCCTGGCTT TGCAACGCCG CTCATCCTGG AAGTCTGTTG CCAGCCGCTG TAAGCCCCAG 
GCTCCTAACC ACCGAGCTGC GGGCCTGGAG AATGGCCACT GCCTCTCCAA GGACAGCAGC 
CCTGTGGGCT TGGTTGAAGA AGCGGGCAGC AGGTCTGCAG GGTGGGGGTT GGCTGAGTGG 
GAGCTGCAGG GCCCTGCCAG CCTCCTCCTA GGCAAGGGGC AGAGCCCTGT GTCCCCTGAG 
ACCTCCTGCT TCTCTACCCT GCATGACTGG TATGGCCAGG AGATCGTGGA GCTGCGGCAG 
TGTTGGCAGA AGAGGGCCCA GGGGAGCCAC TCAAAATGTG AGGAACAGGA TAGGCCCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001002034.2
CDS	191..970
Translation	MKLNERSVAHYALSDSPADHMGFLRTWGGPGTPPTPSGTGRRCWFVLKGNLLFSFESREGRAPLSLVVLEGCTVELAEAPVPEEFAFAICFDAPGVRPHLLAAEGPAAQEAWVKVLSRASFGYMRLVVRELESQLQDARQSLALQRRSSWKSVASRCKPQAPNHRAAGLENGHCLSKDSSPVGLVEEAGSRSAGWGLAEWELQGPASLLLGKGQSPVSPETSCFSTLHDWYGQEIVELRQCWQKRAQGSHSKCEEQDRP

Target ORF information:

RefSeq Version	NM_001002034.3
Organism	Homo sapiens(human)
Definition	Homo sapiens PH domain containing endocytic trafficking adaptor 2 (PHETA2), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001002034.3

ORF Insert Sequence:

ATGAAGCTGA ACGAGAGGAG TGTAGCCCAC TATGCACTCA GCGACTCCCC AGCGGACCAC 
ATGGGCTTCC TGCGCACCTG GGGGGGCCCA GGGACCCCAC CGACCCCCAG TGGCACTGGC 
CGAAGATGCT GGTTTGTCCT CAAGGGCAAC CTGCTATTCT CCTTTGAGAG TCGCGAGGGC 
CGGGCCCCAC TGAGCCTGGT GGTGCTGGAA GGCTGCACAG TGGAACTGGC CGAGGCTCCC 
GTGCCCGAGG AGTTTGCCTT TGCCATCTGC TTTGATGCCC CTGGAGTGCG CCCACACCTG 
CTGGCCGCAG AAGGGCCGGC GGCCCAGGAG GCCTGGGTGA AGGTGCTGTC CCGGGCAAGC 
TTTGGCTACA TGCGCCTGGT GGTACGCGAG TTGGAGAGCC AGTTGCAGGA CGCACGCCAG 
AGCCTGGCTT TGCAACGCCG CTCATCCTGG AAGTCTGTTG CCAGCCGCTG TAAGCCCCAG 
GCTCCTAACC ACCGAGCTGC GGGCCTGGAG AATGGCCACT GCCTCTCCAA GGACAGCAGC 
CCTGTGGGCT TGGTTGAAGA AGCGGGCAGC AGGTCTGCAG GGTGGGGGTT GGCTGAGTGG 
GAGCTGCAGG GCCCTGCCAG CCTCCTCCTA GGCAAGGGGC AGAGCCCTGT GTCCCCTGAG 
ACCTCCTGCT TCTCTACCCT GCATGACTGG TATGGCCAGG AGATCGTGGA GCTGCGGCAG 
TGTTGGCAGA AGAGGGCCCA GGGGAGCCAC TCAAAATGTG AGGAACAGGA TAGGCCCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

FAM109B ( NM_001002034.2 ) cDNA ORF clone, Homo sapiens(Human) -> NP_001002034.2 Homo sapiens family with sequence similarity 109 member B (FAM109B), mRNA.

Price & Availability↑

CloneID	OHu03387
Clone ID Related Accession (Same CDS sequence)	XM_005261373.3 , NM_001002034.3 , NM_001002034.2 , XM_005261373.2
Accession Version	NM_001002034.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 780bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-10-01
Organism	Homo sapiens(human)
Product	sesquipedalian-2
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BX648402.1 and Z82192.1. On Oct 6, 2006 this sequence version replaced NM_001002034.1. ##Evidence-Data-START## Transcript exon combination :: BX648402.1, SRR1660807.30377.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END##

ATGAAGCTGA ACGAGAGGAG TGTAGCCCAC TATGCACTCA GCGACTCCCC AGCGGACCAC 
ATGGGCTTCC TGCGCACCTG GGGGGGCCCA GGGACCCCAC CGACCCCCAG TGGCACTGGC 
CGAAGATGCT GGTTTGTCCT CAAGGGCAAC CTGCTATTCT CCTTTGAGAG TCGCGAGGGC 
CGGGCCCCAC TGAGCCTGGT GGTGCTGGAA GGCTGCACAG TGGAACTGGC CGAGGCTCCC 
GTGCCCGAGG AGTTTGCCTT TGCCATCTGC TTTGATGCCC CTGGAGTGCG CCCACACCTG 
CTGGCCGCAG AAGGGCCGGC GGCCCAGGAG GCCTGGGTGA AGGTGCTGTC CCGGGCAAGC 
TTTGGCTACA TGCGCCTGGT GGTACGCGAG TTGGAGAGCC AGTTGCAGGA CGCACGCCAG 
AGCCTGGCTT TGCAACGCCG CTCATCCTGG AAGTCTGTTG CCAGCCGCTG TAAGCCCCAG 
GCTCCTAACC ACCGAGCTGC GGGCCTGGAG AATGGCCACT GCCTCTCCAA GGACAGCAGC 
CCTGTGGGCT TGGTTGAAGA AGCGGGCAGC AGGTCTGCAG GGTGGGGGTT GGCTGAGTGG 
GAGCTGCAGG GCCCTGCCAG CCTCCTCCTA GGCAAGGGGC AGAGCCCTGT GTCCCCTGAG 
ACCTCCTGCT TCTCTACCCT GCATGACTGG TATGGCCAGG AGATCGTGGA GCTGCGGCAG 
TGTTGGCAGA AGAGGGCCCA GGGGAGCCAC TCAAAATGTG AGGAACAGGA TAGGCCCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001002034.2
CDS	188..967
Translation	MKLNERSVAHYALSDSPADHMGFLRTWGGPGTPPTPSGTGRRCWFVLKGNLLFSFESREGRAPLSLVVLEGCTVELAEAPVPEEFAFAICFDAPGVRPHLLAAEGPAAQEAWVKVLSRASFGYMRLVVRELESQLQDARQSLALQRRSSWKSVASRCKPQAPNHRAAGLENGHCLSKDSSPVGLVEEAGSRSAGWGLAEWELQGPASLLLGKGQSPVSPETSCFSTLHDWYGQEIVELRQCWQKRAQGSHSKCEEQDRP

Target ORF information:

RefSeq Version	NM_001002034.2
Organism	Homo sapiens(human)
Definition	Homo sapiens family with sequence similarity 109 member B (FAM109B), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001002034.2

ORF Insert Sequence:

ATGAAGCTGA ACGAGAGGAG TGTAGCCCAC TATGCACTCA GCGACTCCCC AGCGGACCAC 
ATGGGCTTCC TGCGCACCTG GGGGGGCCCA GGGACCCCAC CGACCCCCAG TGGCACTGGC 
CGAAGATGCT GGTTTGTCCT CAAGGGCAAC CTGCTATTCT CCTTTGAGAG TCGCGAGGGC 
CGGGCCCCAC TGAGCCTGGT GGTGCTGGAA GGCTGCACAG TGGAACTGGC CGAGGCTCCC 
GTGCCCGAGG AGTTTGCCTT TGCCATCTGC TTTGATGCCC CTGGAGTGCG CCCACACCTG 
CTGGCCGCAG AAGGGCCGGC GGCCCAGGAG GCCTGGGTGA AGGTGCTGTC CCGGGCAAGC 
TTTGGCTACA TGCGCCTGGT GGTACGCGAG TTGGAGAGCC AGTTGCAGGA CGCACGCCAG 
AGCCTGGCTT TGCAACGCCG CTCATCCTGG AAGTCTGTTG CCAGCCGCTG TAAGCCCCAG 
GCTCCTAACC ACCGAGCTGC GGGCCTGGAG AATGGCCACT GCCTCTCCAA GGACAGCAGC 
CCTGTGGGCT TGGTTGAAGA AGCGGGCAGC AGGTCTGCAG GGTGGGGGTT GGCTGAGTGG 
GAGCTGCAGG GCCCTGCCAG CCTCCTCCTA GGCAAGGGGC AGAGCCCTGT GTCCCCTGAG 
ACCTCCTGCT TCTCTACCCT GCATGACTGG TATGGCCAGG AGATCGTGGA GCTGCGGCAG 
TGTTGGCAGA AGAGGGCCCA GGGGAGCCAC TCAAAATGTG AGGAACAGGA TAGGCCCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

FAM109B ( XM_005261373.3 ) cDNA ORF clone, Homo sapiens(Human) -> XP_005261430.1 Homo sapiens PH domain containing endocytic trafficking adaptor 2 (PHETA2), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OHu03387
Clone ID Related Accession (Same CDS sequence)	XM_005261373.3 , NM_001002034.3 , NM_001002034.2 , XM_005261373.2
Accession Version	XM_005261373.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 780bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	sesquipedalian-2 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000022.11) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 6, 2016 this sequence version replaced XM_005261373.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGAAGCTGA ACGAGAGGAG TGTAGCCCAC TATGCACTCA GCGACTCCCC AGCGGACCAC 
ATGGGCTTCC TGCGCACCTG GGGGGGCCCA GGGACCCCAC CGACCCCCAG TGGCACTGGC 
CGAAGATGCT GGTTTGTCCT CAAGGGCAAC CTGCTATTCT CCTTTGAGAG TCGCGAGGGC 
CGGGCCCCAC TGAGCCTGGT GGTGCTGGAA GGCTGCACAG TGGAACTGGC CGAGGCTCCC 
GTGCCCGAGG AGTTTGCCTT TGCCATCTGC TTTGATGCCC CTGGAGTGCG CCCACACCTG 
CTGGCCGCAG AAGGGCCGGC GGCCCAGGAG GCCTGGGTGA AGGTGCTGTC CCGGGCAAGC 
TTTGGCTACA TGCGCCTGGT GGTACGCGAG TTGGAGAGCC AGTTGCAGGA CGCACGCCAG 
AGCCTGGCTT TGCAACGCCG CTCATCCTGG AAGTCTGTTG CCAGCCGCTG TAAGCCCCAG 
GCTCCTAACC ACCGAGCTGC GGGCCTGGAG AATGGCCACT GCCTCTCCAA GGACAGCAGC 
CCTGTGGGCT TGGTTGAAGA AGCGGGCAGC AGGTCTGCAG GGTGGGGGTT GGCTGAGTGG 
GAGCTGCAGG GCCCTGCCAG CCTCCTCCTA GGCAAGGGGC AGAGCCCTGT GTCCCCTGAG 
ACCTCCTGCT TCTCTACCCT GCATGACTGG TATGGCCAGG AGATCGTGGA GCTGCGGCAG 
TGTTGGCAGA AGAGGGCCCA GGGGAGCCAC TCAAAATGTG AGGAACAGGA TAGGCCCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_005261430.1
CDS	326..1105
Translation	MKLNERSVAHYALSDSPADHMGFLRTWGGPGTPPTPSGTGRRCWFVLKGNLLFSFESREGRAPLSLVVLEGCTVELAEAPVPEEFAFAICFDAPGVRPHLLAAEGPAAQEAWVKVLSRASFGYMRLVVRELESQLQDARQSLALQRRSSWKSVASRCKPQAPNHRAAGLENGHCLSKDSSPVGLVEEAGSRSAGWGLAEWELQGPASLLLGKGQSPVSPETSCFSTLHDWYGQEIVELRQCWQKRAQGSHSKCEEQDRP

Target ORF information:

RefSeq Version	XM_005261373.3
Organism	Homo sapiens(human)
Definition	Homo sapiens PH domain containing endocytic trafficking adaptor 2 (PHETA2), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_005261373.3

ORF Insert Sequence:

ATGAAGCTGA ACGAGAGGAG TGTAGCCCAC TATGCACTCA GCGACTCCCC AGCGGACCAC 
ATGGGCTTCC TGCGCACCTG GGGGGGCCCA GGGACCCCAC CGACCCCCAG TGGCACTGGC 
CGAAGATGCT GGTTTGTCCT CAAGGGCAAC CTGCTATTCT CCTTTGAGAG TCGCGAGGGC 
CGGGCCCCAC TGAGCCTGGT GGTGCTGGAA GGCTGCACAG TGGAACTGGC CGAGGCTCCC 
GTGCCCGAGG AGTTTGCCTT TGCCATCTGC TTTGATGCCC CTGGAGTGCG CCCACACCTG 
CTGGCCGCAG AAGGGCCGGC GGCCCAGGAG GCCTGGGTGA AGGTGCTGTC CCGGGCAAGC 
TTTGGCTACA TGCGCCTGGT GGTACGCGAG TTGGAGAGCC AGTTGCAGGA CGCACGCCAG 
AGCCTGGCTT TGCAACGCCG CTCATCCTGG AAGTCTGTTG CCAGCCGCTG TAAGCCCCAG 
GCTCCTAACC ACCGAGCTGC GGGCCTGGAG AATGGCCACT GCCTCTCCAA GGACAGCAGC 
CCTGTGGGCT TGGTTGAAGA AGCGGGCAGC AGGTCTGCAG GGTGGGGGTT GGCTGAGTGG 
GAGCTGCAGG GCCCTGCCAG CCTCCTCCTA GGCAAGGGGC AGAGCCCTGT GTCCCCTGAG 
ACCTCCTGCT TCTCTACCCT GCATGACTGG TATGGCCAGG AGATCGTGGA GCTGCGGCAG 
TGTTGGCAGA AGAGGGCCCA GGGGAGCCAC TCAAAATGTG AGGAACAGGA TAGGCCCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

FAM109B ( XM_005261373.2 ) cDNA ORF clone, Homo sapiens(Human) -> XP_005261430.1 Homo sapiens family with sequence similarity 109, member B (FAM109B), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OHu03387
Clone ID Related Accession (Same CDS sequence)	XM_005261373.3 , NM_001002034.3 , NM_001002034.2 , XM_005261373.2
Accession Version	XM_005261373.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 780bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2015-03-11
Organism	Homo sapiens(Human)
Product	sesquipedalian-2 isoform X1
Comment

ATGAAGCTGA ACGAGAGGAG TGTAGCCCAC TATGCACTCA GCGACTCCCC AGCGGACCAC 
ATGGGCTTCC TGCGCACCTG GGGGGGCCCA GGGACCCCAC CGACCCCCAG TGGCACTGGC 
CGAAGATGCT GGTTTGTCCT CAAGGGCAAC CTGCTATTCT CCTTTGAGAG TCGCGAGGGC 
CGGGCCCCAC TGAGCCTGGT GGTGCTGGAA GGCTGCACAG TGGAACTGGC CGAGGCTCCC 
GTGCCCGAGG AGTTTGCCTT TGCCATCTGC TTTGATGCCC CTGGAGTGCG CCCACACCTG 
CTGGCCGCAG AAGGGCCGGC GGCCCAGGAG GCCTGGGTGA AGGTGCTGTC CCGGGCAAGC 
TTTGGCTACA TGCGCCTGGT GGTACGCGAG TTGGAGAGCC AGTTGCAGGA CGCACGCCAG 
AGCCTGGCTT TGCAACGCCG CTCATCCTGG AAGTCTGTTG CCAGCCGCTG TAAGCCCCAG 
GCTCCTAACC ACCGAGCTGC GGGCCTGGAG AATGGCCACT GCCTCTCCAA GGACAGCAGC 
CCTGTGGGCT TGGTTGAAGA AGCGGGCAGC AGGTCTGCAG GGTGGGGGTT GGCTGAGTGG 
GAGCTGCAGG GCCCTGCCAG CCTCCTCCTA GGCAAGGGGC AGAGCCCTGT GTCCCCTGAG 
ACCTCCTGCT TCTCTACCCT GCATGACTGG TATGGCCAGG AGATCGTGGA GCTGCGGCAG 
TGTTGGCAGA AGAGGGCCCA GGGGAGCCAC TCAAAATGTG AGGAACAGGA TAGGCCCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_005261430.1
Translation	MKLNERSVAHYALSDSPADHMGFLRTWGGPGTPPTPSGTGRRCWFVLKGNLLFSFESREGRAPLSLVVLEGCTVELAEAPVPEEFAFAICFDAPGVRPHLLAAEGPAAQEAWVKVLSRASFGYMRLVVRELESQLQDARQSLALQRRSSWKSVASRCKPQAPNHRAAGLENGHCLSKDSSPVGLVEEAGSRSAGWGLAEWELQGPASLLLGKGQSPVSPETSCFSTLHDWYGQEIVELRQCWQKRAQGSHSKCEEQDRP

Target ORF information:

RefSeq Version	XM_005261373.2
Organism	Homo sapiens(Human)
Definition	Homo sapiens family with sequence similarity 109, member B (FAM109B), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_005261373.2

ORF Insert Sequence:

ATGAAGCTGA ACGAGAGGAG TGTAGCCCAC TATGCACTCA GCGACTCCCC AGCGGACCAC 
ATGGGCTTCC TGCGCACCTG GGGGGGCCCA GGGACCCCAC CGACCCCCAG TGGCACTGGC 
CGAAGATGCT GGTTTGTCCT CAAGGGCAAC CTGCTATTCT CCTTTGAGAG TCGCGAGGGC 
CGGGCCCCAC TGAGCCTGGT GGTGCTGGAA GGCTGCACAG TGGAACTGGC CGAGGCTCCC 
GTGCCCGAGG AGTTTGCCTT TGCCATCTGC TTTGATGCCC CTGGAGTGCG CCCACACCTG 
CTGGCCGCAG AAGGGCCGGC GGCCCAGGAG GCCTGGGTGA AGGTGCTGTC CCGGGCAAGC 
TTTGGCTACA TGCGCCTGGT GGTACGCGAG TTGGAGAGCC AGTTGCAGGA CGCACGCCAG 
AGCCTGGCTT TGCAACGCCG CTCATCCTGG AAGTCTGTTG CCAGCCGCTG TAAGCCCCAG 
GCTCCTAACC ACCGAGCTGC GGGCCTGGAG AATGGCCACT GCCTCTCCAA GGACAGCAGC 
CCTGTGGGCT TGGTTGAAGA AGCGGGCAGC AGGTCTGCAG GGTGGGGGTT GGCTGAGTGG 
GAGCTGCAGG GCCCTGCCAG CCTCCTCCTA GGCAAGGGGC AGAGCCCTGT GTCCCCTGAG 
ACCTCCTGCT TCTCTACCCT GCATGACTGG TATGGCCAGG AGATCGTGGA GCTGCGGCAG 
TGTTGGCAGA AGAGGGCCCA GGGGAGCCAC TCAAAATGTG AGGAACAGGA TAGGCCCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Architecture of the human interactome defines protein communities and disease networks.
Nature545(7655)505-509(2017 05)
Huttlin EL,Bruckner RJ,Paulo JA,Cannon JR,Ting L,Baltier K,Colby G,Gebreab F,Gygi MP,Parzen H,Szpyt J,Tam S,Zarraga G,Pontano-Vaites L,Swarup S,White AE,Schweppe DK,Rad R,Erickson BK,Obar RA,Guruharsha KG,Li K,Artavanis-Tsakonas S,Gygi SP,Harper JW

Pooled-matrix protein interaction screens using Barcode Fusion Genetics.
Molecular systems biology12(4)863(2016 Apr)
Yachie N,Petsalaki E,Mellor JC,Weile J,Jacob Y,Verby M,Ozturk SB,Li S,Cote AG,Mosca R,Knapp JJ,Ko M,Yu A,Gebbia M,Sahni N,Yi S,Tyagi T,Sheykhkarimli D,Roth JF,Wong C,Musa L,Snider J,Liu YC,Yu H,Braun P,Stagljar I,Hao T,Calderwood MA,Pelletier L,Aloy P,Hill DE,Vidal M,Roth FP

Biological insights from 108 schizophrenia-associated genetic loci.
Nature511(7510)421-7(2014 Jul)

The PH domain proteins IPIP27A and B link OCRL1 to receptor recycling in the endocytic pathway.
Molecular biology of the cell22(5)606-23(2011 Mar)
Noakes CJ,Lee G,Lowe M

Two closely related endocytic proteins that share a common OCRL-binding motif with APPL1.
Proceedings of the National Academy of Sciences of the United States of America107(8)3511-6(2010 Feb)
Swan LE,Tomasini L,Pirruccello M,Lunardi J,De Camilli P

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FAM109B cDNA ORF clone, Homo sapiens(Human)

Gene

Clones

gRNAs

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Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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