Gene Symbol | ZNF420 |
Entrez Gene ID | 147923 |
Full Name | zinc finger protein 420 |
Synonyms | APAK |
General protein information |
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Gene Type | protein-coding |
Organism | Homo sapiens(human) |
Genome | |
Summary | The protein encoded by this gene is a KRAB-type zinc finger protein that negatively-regulates p53-mediated apoptosis. Under stress conditions, the encoded protein is phosphorylated by ATM and dissociates from p53, which activates p53 and initiates apoptosis. [provided by RefSeq, Jul 2016]. |
Disorder MIM: |