DSG4 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	DSG4
Entrez Gene ID	147409
Full Name	desmoglein 4
Synonyms	CDGF13,CDHF13,HYPT6,LAH
General protein information	Preferred Names desmoglein 4 Names desmoglein-4 cadherin family member 13
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 18 Map Location: 18q12.1
Summary	This gene encodes a member of the desmoglein subgroup of desmosomal cadherins. The encoded preproprotein is proteolytically processed to generate the mature protein. This protein is a transmembrane component of desmosomes and may play a role in cell-cell adhesion in epithelial cells. Mutations in the gene are associated with localized autosomal recessive hypotrichosis and monilethrix, characterized by impaired hair growth. [provided by RefSeq, May 2016].
Disorder MIM:	607892
Disorder Html:	Hypotrichosis 6, 607903 (3)

mRNA and Protein(s)

mRNA	Protein	Name
NM_177986.5	NP_817123.1	desmoglein-4 isoform 2 preproprotein
NM_177986.4	NP_817123.1	desmoglein-4 isoform 2 preproprotein
NM_001134453.2	NP_001127925.1	desmoglein-4 isoform 1 precursor
XM_011525827.1	XP_011524129.1	desmoglein-4 isoform X1

Pathways from BioSystems

Homologies

Bos taurus (cattle)	DSG4	XP_002697734.1
Xenopus tropicalis (tropical clawed frog)	dsg4	XP_002934178.2
Homo sapiens (human)	DSG4	NP_817123.1
Rattus norvegicus (Norway rat)	Dsg4	NP_955784.1
	DSG4	XP_001102180.1
Canis lupus familiaris (dog)	DSG4	XP_005623044.1
Gallus gallus (chicken)	DSG4	XP_426082.4
Pan troglodytes (chimpanzee)	DSG4	XP_003953318.1
Mus musculus (house mouse)	Dsg4	NP_853543.1

Gene Ontology
Bibliography

Related articles in PubMed

Novel D323G mutation of DSG4 gene in a girl with localized autosomal recessive hypotrichosis clinically overlapped with monilethrix.
Wang JM, Xiao YJ, Liang YH
International journal of dermatology54(10)1163-8(2015 Oct)

An autosomal recessive mutation of DSG4 causes monilethrix through the ER stress response.
Kato M, Shimizu A, Yokoyama Y, Kaira K, Shimomura Y, Ishida-Yamamoto A, Kamei K, Tokunaga F, Ishikawa O
The Journal of investigative dermatology135(5)1253-1260(2015 May)

A novel deletion mutation in the DSG4 gene underlies autosomal recessive hypotrichosis with variable phenotype in two unrelated consanguineous families.
Ullah A, Raza SI, Ali RH, Naveed AK, Jan A, Rizvi SD, Satti R, Ahmad W
Clinical and experimental dermatology40(1)78-84(2015 Jan)

Desmoglein as a target in skin disease and beyond.
Amagai M, Stanley JR
The Journal of investigative dermatology132(3 Pt 2)776-84(2012 Mar)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

This study further extends the body of evidence that mutations in the DSG4 gene result in both hypotrichosis and monilethrix-like scalp hair.
Title: A novel deletion mutation in the DSG4 gene underlies autosomal recessive hypotrichosis with variable phenotype in two unrelated consanguineous families.

Genetic analysis of striate palmoplantar keratoderma and hypotrichosis identified their responsible genes as desmogleins 1 and 4, respectively.
Title: Desmoglein as a target in skin disease and beyond.

show that HOXC13, LEF1 and FOXN1 repress DSG4 transcription and provide in vitro and in vivo evidence correlating the Notch pathway with the activation and/or maintenance of DSG4 expression in the hair follicle.
Title: Desmoglein 4 is regulated by transcription factors implicated in hair shaft differentiation.

identification of a single nucleotide deletion within exon 3 of DSG4, designated 87delG in a Pakistani family with localized autosomal recessive hypotrichosis; this results in a frameshift and premature termination codon 162 bp downstream of the deletion
Title: Localized autosomal recessive hypotrichosis due to a frameshift mutation in the desmoglein 4 gene exhibits extensive phenotypic variability within a Pakistani family.

Epitopes of Dsg4 may play a role in the pathogenesis of pemphigus vulgaris .
Title: [Gene fragments cloned and immune recognition studied preliminarily for desmoglein 4 in pemphigus vulgaris].

The following DSG4 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the DSG4 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu76330	XM_011525827.1 Latest version!	Homo sapiens desmoglein 4 (DSG4), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$307.30 $439.00
OHu22937	NM_177986.5 Latest version!	Homo sapiens desmoglein 4 (DSG4), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	20	$559.30 $799.00
OHu31898	NM_001134453.2 Latest version!	Homo sapiens desmoglein 4 (DSG4), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	20	$559.30 $799.00
View Old Accession Versions >>
OHu22937	NM_177986.4	Homo sapiens desmoglein 4 (DSG4), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	20	$559.30 $799.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

DSG4 ( XM_011525827.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_011524129.1 Homo sapiens desmoglein 4 (DSG4), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OHu76330
Clone ID Related Accession (Same CDS sequence)	XM_011525827.1
Accession Version	XM_011525827.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1725bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	desmoglein-4 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000018.10) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGACCCTTA CTCTTTCAGA TGGCTCTGGA AAAACAGCTA CAGGAACCAT ATGTATTGAG 
GTTCCTGATA TCAATGATTA TTGTCCAAAC ATTTTTCCTG AAAGAAGAAC CATCTGCATT 
GACTCTCCAT CAGTCCTTAT CTCTGTTAAT GAACATTCTT ATGGGTCTCC GTTTACTTTC 
TGTGTTGTTG ATGAGCCACC AGGAATAGCT GACATGTGGG ATGTCAGATC AACAAATGCT 
ACCTCGGCAA TCCTTACGGC TAAGCAGGTT TTATCTCCAG GATTTTATGA AATCCCAATC 
CTGGTGAAGG ACAGCTATAA CAGAGCATGT GAATTGGCAC AAATGGTGCA GTTATATGCC 
TGTGATTGCG ATGACAACCA CATGTGCCTG GACTCTGGTG CCGCGGGCAT CTACACAGAG 
GACATAACTG GTGACACGTA TGGGCCTGTC ACTGAAGACC AAGCTGGAGT TTCAAATGTT 
GGTCTTGGAC CAGCAGGGAT TGGCATGATG GTTCTGGGCA TCCTGCTACT GATTTTGGCT 
CCACTCTTGC TGCTCCTGTG TTGCTGCAAA CAGAGACAGC CAGAAGGCCT GGGAACAAGA 
TTTGCTCCTG TGCCTGAGGG CGGAGAAGGA GTGATGCAGT CTTGGAGAAT TGAAGGGGCC 
CATCCCGAGG ACAGGGATGT GTCAAATATA TGTGCACCCA TGACAGCCTC AAATACCCAG 
GATCGGATGG ATTCCTCTGA AATCTACACC AACACCTATG CAGCCGGGGG CACGGTGGAA 
GGAGGTGTAT CGGGAGTGGA GCTCAACACA GGTATGGGGA CAGCCGTTGG CCTCATGGCC 
GCAGGGGCCG CAGGAGCCTC AGGGGCCGCA AGGAAGAGGA GCTCTACCAT GGGAACCCTG 
CGGGACTACG CTGACGCAGA CATCAACATG GCTTTCTTGG ACAGCTACTT CTCGGAGAAA 
GCGTATGCTT ATGCAGATGA AGATGAAGGT CGACCAGCCA ATGACTGCTT GCTCATTTAT 
GACCACGAGG GAGTCGGGTC TCCCGTAGGC TCTATTGGTT GTTGCAGTTG GATTGTGGAT 
GACTTAGATG AAAGCTGCAT GGAAACTTTA GATCCAAAAT TTAGGACTCT TGCTGAGATC 
TGCTTAAACA CAGAAATTGA ACCATTTCCT TCACACCAGG CTTGTATACC AATCAGTACT 
GACCTCCCTT TGCTCGGACC TAATTACTTT GTTAATGAAT CTTCAGGATT GACTCCCTCA 
GAAGTTGAAT TCCAAGAAGA AATGGCAGCA TCTGAACCCG TGGTCCATGG GGATATTATT 
GTGACTGAGA CTTACGGTAA TGCTGATCCA TGTGTGCAAC CCACTACAAT TATTTTTGAT 
CCTCAGCTTG CACCCAATGT TGTAGTAACC GAAGCAGTAA TGGCACCTGT CTATGATATT 
CAAGGGAATA TTTGTGTACC TGCTGAGTTA GCAGATTACA ACAATGTAAT CTATGCTGAG 
AGAGTACTGG CTAGTCCTGG TGTGCCTGAC ATGAGCAATA GTAGCACGAC TGAGGGTTGT 
ATGGGACCTG TGATGAGCGG CAATATTTTA GTAGGGCCAG AAATTCAAGT GATGCAAATG 
ATGAGTCCAG ACCTTCCCAT AGGCCAAACC GTTGGCTCCA CATCCCCCAT GACATCTCGA 
CACAGAGTAA CACGATACAG TAACATACAT TACACCCAAC AGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_011524129.1
CDS	1449..3173
Translation	MTLTLSDGSGKTATGTICIEVPDINDYCPNIFPERRTICIDSPSVLISVNEHSYGSPFTFCVVDEPPGIADMWDVRSTNATSAILTAKQVLSPGFYEIPILVKDSYNRACELAQMVQLYACDCDDNHMCLDSGAAGIYTEDITGDTYGPVTEDQAGVSNVGLGPAGIGMMVLGILLLILAPLLLLLCCCKQRQPEGLGTRFAPVPEGGEGVMQSWRIEGAHPEDRDVSNICAPMTASNTQDRMDSSEIYTNTYAAGGTVEGGVSGVELNTGMGTAVGLMAAGAAGASGAARKRSSTMGTLRDYADADINMAFLDSYFSEKAYAYADEDEGRPANDCLLIYDHEGVGSPVGSIGCCSWIVDDLDESCMETLDPKFRTLAEICLNTEIEPFPSHQACIPISTDLPLLGPNYFVNESSGLTPSEVEFQEEMAASEPVVHGDIIVTETYGNADPCVQPTTIIFDPQLAPNVVVTEAVMAPVYDIQGNICVPAELADYNNVIYAERVLASPGVPDMSNSSTTEGCMGPVMSGNILVGPEIQVMQMMSPDLPIGQTVGSTSPMTSRHRVTRYSNIHYTQQ

Target ORF information:

RefSeq Version	XM_011525827.1
Organism	Homo sapiens(human)
Definition	Homo sapiens desmoglein 4 (DSG4), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011525827.1

ORF Insert Sequence:

ATGACCCTTA CTCTTTCAGA TGGCTCTGGA AAAACAGCTA CAGGAACCAT ATGTATTGAG 
GTTCCTGATA TCAATGATTA TTGTCCAAAC ATTTTTCCTG AAAGAAGAAC CATCTGCATT 
GACTCTCCAT CAGTCCTTAT CTCTGTTAAT GAACATTCTT ATGGGTCTCC GTTTACTTTC 
TGTGTTGTTG ATGAGCCACC AGGAATAGCT GACATGTGGG ATGTCAGATC AACAAATGCT 
ACCTCGGCAA TCCTTACGGC TAAGCAGGTT TTATCTCCAG GATTTTATGA AATCCCAATC 
CTGGTGAAGG ACAGCTATAA CAGAGCATGT GAATTGGCAC AAATGGTGCA GTTATATGCC 
TGTGATTGCG ATGACAACCA CATGTGCCTG GACTCTGGTG CCGCGGGCAT CTACACAGAG 
GACATAACTG GTGACACGTA TGGGCCTGTC ACTGAAGACC AAGCTGGAGT TTCAAATGTT 
GGTCTTGGAC CAGCAGGGAT TGGCATGATG GTTCTGGGCA TCCTGCTACT GATTTTGGCT 
CCACTCTTGC TGCTCCTGTG TTGCTGCAAA CAGAGACAGC CAGAAGGCCT GGGAACAAGA 
TTTGCTCCTG TGCCTGAGGG CGGAGAAGGA GTGATGCAGT CTTGGAGAAT TGAAGGGGCC 
CATCCCGAGG ACAGGGATGT GTCAAATATA TGTGCACCCA TGACAGCCTC AAATACCCAG 
GATCGGATGG ATTCCTCTGA AATCTACACC AACACCTATG CAGCCGGGGG CACGGTGGAA 
GGAGGTGTAT CGGGAGTGGA GCTCAACACA GGTATGGGGA CAGCCGTTGG CCTCATGGCC 
GCAGGGGCCG CAGGAGCCTC AGGGGCCGCA AGGAAGAGGA GCTCTACCAT GGGAACCCTG 
CGGGACTACG CTGACGCAGA CATCAACATG GCTTTCTTGG ACAGCTACTT CTCGGAGAAA 
GCGTATGCTT ATGCAGATGA AGATGAAGGT CGACCAGCCA ATGACTGCTT GCTCATTTAT 
GACCACGAGG GAGTCGGGTC TCCCGTAGGC TCTATTGGTT GTTGCAGTTG GATTGTGGAT 
GACTTAGATG AAAGCTGCAT GGAAACTTTA GATCCAAAAT TTAGGACTCT TGCTGAGATC 
TGCTTAAACA CAGAAATTGA ACCATTTCCT TCACACCAGG CTTGTATACC AATCAGTACT 
GACCTCCCTT TGCTCGGACC TAATTACTTT GTTAATGAAT CTTCAGGATT GACTCCCTCA 
GAAGTTGAAT TCCAAGAAGA AATGGCAGCA TCTGAACCCG TGGTCCATGG GGATATTATT 
GTGACTGAGA CTTACGGTAA TGCTGATCCA TGTGTGCAAC CCACTACAAT TATTTTTGAT 
CCTCAGCTTG CACCCAATGT TGTAGTAACC GAAGCAGTAA TGGCACCTGT CTATGATATT 
CAAGGGAATA TTTGTGTACC TGCTGAGTTA GCAGATTACA ACAATGTAAT CTATGCTGAG 
AGAGTACTGG CTAGTCCTGG TGTGCCTGAC ATGAGCAATA GTAGCACGAC TGAGGGTTGT 
ATGGGACCTG TGATGAGCGG CAATATTTTA GTAGGGCCAG AAATTCAAGT GATGCAAATG 
ATGAGTCCAG ACCTTCCCAT AGGCCAAACC GTTGGCTCCA CATCCCCCAT GACATCTCGA 
CACAGAGTAA CACGATACAG TAACATACAT TACACCCAAC AGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

DSG4 ( NM_177986.5 ) cDNA ORF clone, Homo sapiens(human) -> NP_817123.1 Homo sapiens desmoglein 4 (DSG4), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu22937
Clone ID Related Accession (Same CDS sequence)	NM_177986.5 , NM_177986.4
Accession Version	NM_177986.5 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 3123bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-10-24
Organism	Homo sapiens(human)
Product	desmoglein-4 isoform 2 preproprotein
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AY177664.1, BC039098.1 and AC021549.9. This sequence is a reference standard in the RefSeqGene project. On May 17, 2019 this sequence version replaced NM_177986.4. Transcript Variant: This variant (2) represents the shorter transcript and encodes the shorter isoform (2). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AY177664.1, BC132907.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA2145893, SAMEA2147596 [ECO:0000350] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000308128.9/ ENSP00000311859.4 RefSeq Select criteria :: based on conservation, expression ##RefSeq-Attributes-END##

ATGGATTGGC TCTTCTTCAG AAACATTTGC CTTTTGATCA TTCTAATGGT GGTGATGGAA 
GTAAACAGTG AATTTATTGT TGAGGTGAAG GAATTTGACA TTGAAAATGG CACTACAAAA 
TGGCAAACAG TCAGAAGACA AAAGCGGGAG TGGATCAAGT TTGCCGCAGC CTGTCGAGAA 
GGAGAGGACA ACTCGAAGAG GAACCCCATT GCCAAAATTC GATCAGACTG CGAATCGAAC 
CAGAAGATAA CATACCGGAT TTCTGGAGTA GGGATTGATC GACCACCATA TGGGGTATTC 
ACCATTAATC CTCGCACTGG GGAAATTAAC ATCACTTCAG TGGTAGACAG AGAAATAACT 
CCACTTTTCT TGATCTATTG CCGGGCTCTG AATTCACGGG GTGAAGATTT AGAAAGGCCT 
CTTGAGCTTA GAGTCAAAGT TATGGACATA AATGATAACG CTCCAGTCTT TTCGCAAAGT 
GTATACACAG CCAGCATTGA AGAAAATAGT GATGCCAATA CATTGGTAGT AAAGTTATGT 
GCCACAGATG CAGATGAAGA AAATCATCTG AATTCTAAAA TTGCCTACAA GATCGTCTCT 
CAGGAGCCAT CAGGTGCACC CATGTTCATT CTGAATAGGT ACACTGGAGA AGTCTGCACC 
ATGTCCAGTT TCTTGGACAG AGAGCAACAC AGTATGTACA ACCTGGTTGT GAGAGGCTCA 
GATCGGGATG GAGCTGCAGA TGGACTGTCT TCTGAGTGTG ACTGTAGAAT CAAGGTTTTA 
GACGTCAACG ATAATTTCCC CACCTTAGAG AAAACTTCAT ACTCAGCCAG TATTGAAGAG 
AATTGTTTAA GTTCGGAACT GATACGATTA CAAGCAATTG ATCTTGATGA AGAAGGCACT 
GATAACTGGT TGGCTCAATA TTTAATTCTC TCTGGAAATG ATGGGAATTG GTTCGATATT 
CAAACAGATC CACAAACCAA TGAAGGCATT TTGAAAGTTG TCAAGATGCT GGATTATGAA 
CAAGCACCTA ACATTCAGCT TAGTATCGGA GTTAAAAACC AAGCTGATTT TCACTACTCC 
GTTGCTTCTC AATTCCAAAT GCACCCAACC CCTGTGAGAA TTCAAGTTGT TGATGTGAGA 
GAAGGACCTG CATTTCATCC AAGTACTATG GCTTTTAGTG TGCGGGAAGG AATAAAAGGA 
AGTTCCTTAT TGAATTATGT GCTTGGCACA TATACAGCCA TAGATTTGGA CACAGGAAAC 
CCTGCAACAG ATGTCAGATA TATCATAGGG CATGATGCAG GCAGCTGGTT AAAAATTGAT 
TCAAGAACTG GTGAGATACA ATTTTCTAGA GAATTTGATA AGAAGTCAAA ATATATTATC 
AATGGGATAT ACACAGCAGA GATCCTGGCT ATAGATGATG GCTCTGGAAA AACAGCTACA 
GGAACCATAT GTATTGAGGT TCCTGATATC AATGATTATT GTCCAAACAT TTTTCCTGAA 
AGAAGAACCA TCTGCATTGA CTCTCCATCA GTCCTTATCT CTGTTAATGA ACATTCTTAT 
GGGTCTCCGT TTACTTTCTG TGTTGTTGAT GAGCCACCAG GAATAGCTGA CATGTGGGAT 
GTCAGATCAA CAAATGCTAC CTCGGCAATC CTTACGGCTA AGCAGGTTTT ATCTCCAGGA 
TTTTATGAAA TCCCAATCCT GGTGAAGGAC AGCTATAACA GAGCATGTGA ATTGGCACAA 
ATGGTGCAGT TATATGCCTG TGATTGCGAT GACAACCACA TGTGCCTGGA CTCTGGTGCC 
GCGGGCATCT ACACAGAGGA CATAACTGGT GACACGTATG GGCCTGTCAC TGAAGACCAA 
GCTGGAGTTT CAAATGTTGG TCTTGGACCA GCAGGGATTG GCATGATGGT TCTGGGCATC 
CTGCTACTGA TTTTGGCTCC ACTCTTGCTG CTCCTGTGTT GCTGCAAACA GAGACAGCCA 
GAAGGCCTGG GAACAAGATT TGCTCCTGTG CCTGAGGGCG GAGAAGGAGT GATGCAGTCT 
TGGAGAATTG AAGGGGCCCA TCCCGAGGAC AGGGATGTGT CAAATATATG TGCACCCATG 
ACAGCCTCAA ATACCCAGGA TCGGATGGAT TCCTCTGAAA TCTACACCAA CACCTATGCA 
GCCGGGGGCA CGGTGGAAGG AGGTGTATCG GGAGTGGAGC TCAACACAGG TATGGGGACA 
GCCGTTGGCC TCATGGCCGC AGGGGCCGCA GGAGCCTCAG GGGCCGCAAG GAAGAGGAGC 
TCTACCATGG GAACCCTGCG GGACTACGCT GACGCAGACA TCAACATGGC TTTCTTGGAC 
AGCTACTTCT CGGAGAAAGC GTATGCTTAT GCAGATGAAG ATGAAGGTCG ACCAGCCAAT 
GACTGCTTGC TCATTTATGA CCACGAGGGA GTCGGGTCTC CCGTAGGCTC TATTGGTTGT 
TGCAGTTGGA TTGTGGATGA CTTAGATGAA AGCTGCATGG AAACTTTAGA TCCAAAATTT 
AGGACTCTTG CTGAGATCTG CTTAAACACA GAAATTGAAC CATTTCCTTC ACACCAGGCT 
TGTATACCAA TCAGTACTGA CCTCCCTTTG CTCGGACCTA ATTACTTTGT TAATGAATCT 
TCAGGATTGA CTCCCTCAGA AGTTGAATTC CAAGAAGAAA TGGCAGCATC TGAACCCGTG 
GTCCATGGGG ATATTATTGT GACTGAGACT TACGGTAATG CTGATCCATG TGTGCAACCC 
ACTACAATTA TTTTTGATCC TCAGCTTGCA CCCAATGTTG TAGTAACCGA AGCAGTAATG 
GCACCTGTCT ATGATATTCA AGGGAATATT TGTGTACCTG CTGAGTTAGC AGATTACAAC 
AATGTAATCT ATGCTGAGAG AGTACTGGCT AGTCCTGGTG TGCCTGACAT GAGCAATAGT 
AGCACGACTG AGGGTTGTAT GGGACCTGTG ATGAGCGGCA ATATTTTAGT AGGGCCAGAA 
ATTCAAGTGA TGCAAATGAT GAGTCCAGAC CTTCCCATAG GCCAAACCGT TGGCTCCACA 
TCCCCCATGA CATCTCGACA CAGAGTAACA CGATACAGTA ACATACATTA CACCCAACAG 
TAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_817123.1
CDS	136..3258
Translation	MDWLFFRNICLLIILMVVMEVNSEFIVEVKEFDIENGTTKWQTVRRQKREWIKFAAACREGEDNSKRNPIAKIRSDCESNQKITYRISGVGIDRPPYGVFTINPRTGEINITSVVDREITPLFLIYCRALNSRGEDLERPLELRVKVMDINDNAPVFSQSVYTASIEENSDANTLVVKLCATDADEENHLNSKIAYKIVSQEPSGAPMFILNRYTGEVCTMSSFLDREQHSMYNLVVRGSDRDGAADGLSSECDCRIKVLDVNDNFPTLEKTSYSASIEENCLSSELIRLQAIDLDEEGTDNWLAQYLILSGNDGNWFDIQTDPQTNEGILKVVKMLDYEQAPNIQLSIGVKNQADFHYSVASQFQMHPTPVRIQVVDVREGPAFHPSTMAFSVREGIKGSSLLNYVLGTYTAIDLDTGNPATDVRYIIGHDAGSWLKIDSRTGEIQFSREFDKKSKYIINGIYTAEILAIDDGSGKTATGTICIEVPDINDYCPNIFPERRTICIDSPSVLISVNEHSYGSPFTFCVVDEPPGIADMWDVRSTNATSAILTAKQVLSPGFYEIPILVKDSYNRACELAQMVQLYACDCDDNHMCLDSGAAGIYTEDITGDTYGPVTEDQAGVSNVGLGPAGIGMMVLGILLLILAPLLLLLCCCKQRQPEGLGTRFAPVPEGGEGVMQSWRIEGAHPEDRDVSNICAPMTASNTQDRMDSSEIYTNTYAAGGTVEGGVSGVELNTGMGTAVGLMAAGAAGASGAARKRSSTMGTLRDYADADINMAFLDSYFSEKAYAYADEDEGRPANDCLLIYDHEGVGSPVGSIGCCSWIVDDLDESCMETLDPKFRTLAEICLNTEIEPFPSHQACIPISTDLPLLGPNYFVNESSGLTPSEVEFQEEMAASEPVVHGDIIVTETYGNADPCVQPTTIIFDPQLAPNVVVTEAVMAPVYDIQGNICVPAELADYNNVIYAERVLASPGVPDMSNSSTTEGCMGPVMSGNILVGPEIQVMQMMSPDLPIGQTVGSTSPMTSRHRVTRYSNIHYTQQ

Target ORF information:

RefSeq Version	NM_177986.5
Organism	Homo sapiens(human)
Definition	Homo sapiens desmoglein 4 (DSG4), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_177986.5

ORF Insert Sequence:

ATGGATTGGC TCTTCTTCAG AAACATTTGC CTTTTGATCA TTCTAATGGT GGTGATGGAA 
GTAAACAGTG AATTTATTGT TGAGGTGAAG GAATTTGACA TTGAAAATGG CACTACAAAA 
TGGCAAACAG TCAGAAGACA AAAGCGGGAG TGGATCAAGT TTGCCGCAGC CTGTCGAGAA 
GGAGAGGACA ACTCGAAGAG GAACCCCATT GCCAAAATTC GATCAGACTG CGAATCGAAC 
CAGAAGATAA CATACCGGAT TTCTGGAGTA GGGATTGATC GACCACCATA TGGGGTATTC 
ACCATTAATC CTCGCACTGG GGAAATTAAC ATCACTTCAG TGGTAGACAG AGAAATAACT 
CCACTTTTCT TGATCTATTG CCGGGCTCTG AATTCACGGG GTGAAGATTT AGAAAGGCCT 
CTTGAGCTTA GAGTCAAAGT TATGGACATA AATGATAACG CTCCAGTCTT TTCGCAAAGT 
GTATACACAG CCAGCATTGA AGAAAATAGT GATGCCAATA CATTGGTAGT AAAGTTATGT 
GCCACAGATG CAGATGAAGA AAATCATCTG AATTCTAAAA TTGCCTACAA GATCGTCTCT 
CAGGAGCCAT CAGGTGCACC CATGTTCATT CTGAATAGGT ACACTGGAGA AGTCTGCACC 
ATGTCCAGTT TCTTGGACAG AGAGCAACAC AGTATGTACA ACCTGGTTGT GAGAGGCTCA 
GATCGGGATG GAGCTGCAGA TGGACTGTCT TCTGAGTGTG ACTGTAGAAT CAAGGTTTTA 
GACGTCAACG ATAATTTCCC CACCTTAGAG AAAACTTCAT ACTCAGCCAG TATTGAAGAG 
AATTGTTTAA GTTCGGAACT GATACGATTA CAAGCAATTG ATCTTGATGA AGAAGGCACT 
GATAACTGGT TGGCTCAATA TTTAATTCTC TCTGGAAATG ATGGGAATTG GTTCGATATT 
CAAACAGATC CACAAACCAA TGAAGGCATT TTGAAAGTTG TCAAGATGCT GGATTATGAA 
CAAGCACCTA ACATTCAGCT TAGTATCGGA GTTAAAAACC AAGCTGATTT TCACTACTCC 
GTTGCTTCTC AATTCCAAAT GCACCCAACC CCTGTGAGAA TTCAAGTTGT TGATGTGAGA 
GAAGGACCTG CATTTCATCC AAGTACTATG GCTTTTAGTG TGCGGGAAGG AATAAAAGGA 
AGTTCCTTAT TGAATTATGT GCTTGGCACA TATACAGCCA TAGATTTGGA CACAGGAAAC 
CCTGCAACAG ATGTCAGATA TATCATAGGG CATGATGCAG GCAGCTGGTT AAAAATTGAT 
TCAAGAACTG GTGAGATACA ATTTTCTAGA GAATTTGATA AGAAGTCAAA ATATATTATC 
AATGGGATAT ACACAGCAGA GATCCTGGCT ATAGATGATG GCTCTGGAAA AACAGCTACA 
GGAACCATAT GTATTGAGGT TCCTGATATC AATGATTATT GTCCAAACAT TTTTCCTGAA 
AGAAGAACCA TCTGCATTGA CTCTCCATCA GTCCTTATCT CTGTTAATGA ACATTCTTAT 
GGGTCTCCGT TTACTTTCTG TGTTGTTGAT GAGCCACCAG GAATAGCTGA CATGTGGGAT 
GTCAGATCAA CAAATGCTAC CTCGGCAATC CTTACGGCTA AGCAGGTTTT ATCTCCAGGA 
TTTTATGAAA TCCCAATCCT GGTGAAGGAC AGCTATAACA GAGCATGTGA ATTGGCACAA 
ATGGTGCAGT TATATGCCTG TGATTGCGAT GACAACCACA TGTGCCTGGA CTCTGGTGCC 
GCGGGCATCT ACACAGAGGA CATAACTGGT GACACGTATG GGCCTGTCAC TGAAGACCAA 
GCTGGAGTTT CAAATGTTGG TCTTGGACCA GCAGGGATTG GCATGATGGT TCTGGGCATC 
CTGCTACTGA TTTTGGCTCC ACTCTTGCTG CTCCTGTGTT GCTGCAAACA GAGACAGCCA 
GAAGGCCTGG GAACAAGATT TGCTCCTGTG CCTGAGGGCG GAGAAGGAGT GATGCAGTCT 
TGGAGAATTG AAGGGGCCCA TCCCGAGGAC AGGGATGTGT CAAATATATG TGCACCCATG 
ACAGCCTCAA ATACCCAGGA TCGGATGGAT TCCTCTGAAA TCTACACCAA CACCTATGCA 
GCCGGGGGCA CGGTGGAAGG AGGTGTATCG GGAGTGGAGC TCAACACAGG TATGGGGACA 
GCCGTTGGCC TCATGGCCGC AGGGGCCGCA GGAGCCTCAG GGGCCGCAAG GAAGAGGAGC 
TCTACCATGG GAACCCTGCG GGACTACGCT GACGCAGACA TCAACATGGC TTTCTTGGAC 
AGCTACTTCT CGGAGAAAGC GTATGCTTAT GCAGATGAAG ATGAAGGTCG ACCAGCCAAT 
GACTGCTTGC TCATTTATGA CCACGAGGGA GTCGGGTCTC CCGTAGGCTC TATTGGTTGT 
TGCAGTTGGA TTGTGGATGA CTTAGATGAA AGCTGCATGG AAACTTTAGA TCCAAAATTT 
AGGACTCTTG CTGAGATCTG CTTAAACACA GAAATTGAAC CATTTCCTTC ACACCAGGCT 
TGTATACCAA TCAGTACTGA CCTCCCTTTG CTCGGACCTA ATTACTTTGT TAATGAATCT 
TCAGGATTGA CTCCCTCAGA AGTTGAATTC CAAGAAGAAA TGGCAGCATC TGAACCCGTG 
GTCCATGGGG ATATTATTGT GACTGAGACT TACGGTAATG CTGATCCATG TGTGCAACCC 
ACTACAATTA TTTTTGATCC TCAGCTTGCA CCCAATGTTG TAGTAACCGA AGCAGTAATG 
GCACCTGTCT ATGATATTCA AGGGAATATT TGTGTACCTG CTGAGTTAGC AGATTACAAC 
AATGTAATCT ATGCTGAGAG AGTACTGGCT AGTCCTGGTG TGCCTGACAT GAGCAATAGT 
AGCACGACTG AGGGTTGTAT GGGACCTGTG ATGAGCGGCA ATATTTTAGT AGGGCCAGAA 
ATTCAAGTGA TGCAAATGAT GAGTCCAGAC CTTCCCATAG GCCAAACCGT TGGCTCCACA 
TCCCCCATGA CATCTCGACA CAGAGTAACA CGATACAGTA ACATACATTA CACCCAACAG 
TAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

DSG4 ( NM_177986.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_817123.1 Homo sapiens desmoglein 4 (DSG4), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu22937
Clone ID Related Accession (Same CDS sequence)	NM_177986.5 , NM_177986.4
Accession Version	NM_177986.4	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 3123bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-02-24
Organism	Homo sapiens(human)
Product	desmoglein-4 isoform 2 preproprotein
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AY177664.1, BC039098.1 and AC021549.9. This sequence is a reference standard in the RefSeqGene project. On May 13, 2016 this sequence version replaced NM_177986.3. Transcript Variant: This variant (2) represents the shorter transcript and encodes the shorter isoform (2). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AY177664.1, BC132907.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA2145893, SAMEA2147596 [ECO:0000350] ##Evidence-Data-END##

ATGGATTGGC TCTTCTTCAG AAACATTTGC CTTTTGATCA TTCTAATGGT GGTGATGGAA 
GTAAACAGTG AATTTATTGT TGAGGTGAAG GAATTTGACA TTGAAAATGG CACTACAAAA 
TGGCAAACAG TCAGAAGACA AAAGCGGGAG TGGATCAAGT TTGCCGCAGC CTGTCGAGAA 
GGAGAGGACA ACTCGAAGAG GAACCCCATT GCCAAAATTC GATCAGACTG CGAATCGAAC 
CAGAAGATAA CATACCGGAT TTCTGGAGTA GGGATTGATC GACCACCATA TGGGGTATTC 
ACCATTAATC CTCGCACTGG GGAAATTAAC ATCACTTCAG TGGTAGACAG AGAAATAACT 
CCACTTTTCT TGATCTATTG CCGGGCTCTG AATTCACGGG GTGAAGATTT AGAAAGGCCT 
CTTGAGCTTA GAGTCAAAGT TATGGACATA AATGATAACG CTCCAGTCTT TTCGCAAAGT 
GTATACACAG CCAGCATTGA AGAAAATAGT GATGCCAATA CATTGGTAGT AAAGTTATGT 
GCCACAGATG CAGATGAAGA AAATCATCTG AATTCTAAAA TTGCCTACAA GATCGTCTCT 
CAGGAGCCAT CAGGTGCACC CATGTTCATT CTGAATAGGT ACACTGGAGA AGTCTGCACC 
ATGTCCAGTT TCTTGGACAG AGAGCAACAC AGTATGTACA ACCTGGTTGT GAGAGGCTCA 
GATCGGGATG GAGCTGCAGA TGGACTGTCT TCTGAGTGTG ACTGTAGAAT CAAGGTTTTA 
GACGTCAACG ATAATTTCCC CACCTTAGAG AAAACTTCAT ACTCAGCCAG TATTGAAGAG 
AATTGTTTAA GTTCGGAACT GATACGATTA CAAGCAATTG ATCTTGATGA AGAAGGCACT 
GATAACTGGT TGGCTCAATA TTTAATTCTC TCTGGAAATG ATGGGAATTG GTTCGATATT 
CAAACAGATC CACAAACCAA TGAAGGCATT TTGAAAGTTG TCAAGATGCT GGATTATGAA 
CAAGCACCTA ACATTCAGCT TAGTATCGGA GTTAAAAACC AAGCTGATTT TCACTACTCC 
GTTGCTTCTC AATTCCAAAT GCACCCAACC CCTGTGAGAA TTCAAGTTGT TGATGTGAGA 
GAAGGACCTG CATTTCATCC AAGTACTATG GCTTTTAGTG TGCGGGAAGG AATAAAAGGA 
AGTTCCTTAT TGAATTATGT GCTTGGCACA TATACAGCCA TAGATTTGGA CACAGGAAAC 
CCTGCAACAG ATGTCAGATA TATCATAGGG CATGATGCAG GCAGCTGGTT AAAAATTGAT 
TCAAGAACTG GTGAGATACA ATTTTCTAGA GAATTTGATA AGAAGTCAAA ATATATTATC 
AATGGGATAT ACACAGCAGA GATCCTGGCT ATAGATGATG GCTCTGGAAA AACAGCTACA 
GGAACCATAT GTATTGAGGT TCCTGATATC AATGATTATT GTCCAAACAT TTTTCCTGAA 
AGAAGAACCA TCTGCATTGA CTCTCCATCA GTCCTTATCT CTGTTAATGA ACATTCTTAT 
GGGTCTCCGT TTACTTTCTG TGTTGTTGAT GAGCCACCAG GAATAGCTGA CATGTGGGAT 
GTCAGATCAA CAAATGCTAC CTCGGCAATC CTTACGGCTA AGCAGGTTTT ATCTCCAGGA 
TTTTATGAAA TCCCAATCCT GGTGAAGGAC AGCTATAACA GAGCATGTGA ATTGGCACAA 
ATGGTGCAGT TATATGCCTG TGATTGCGAT GACAACCACA TGTGCCTGGA CTCTGGTGCC 
GCGGGCATCT ACACAGAGGA CATAACTGGT GACACGTATG GGCCTGTCAC TGAAGACCAA 
GCTGGAGTTT CAAATGTTGG TCTTGGACCA GCAGGGATTG GCATGATGGT TCTGGGCATC 
CTGCTACTGA TTTTGGCTCC ACTCTTGCTG CTCCTGTGTT GCTGCAAACA GAGACAGCCA 
GAAGGCCTGG GAACAAGATT TGCTCCTGTG CCTGAGGGCG GAGAAGGAGT GATGCAGTCT 
TGGAGAATTG AAGGGGCCCA TCCCGAGGAC AGGGATGTGT CAAATATATG TGCACCCATG 
ACAGCCTCAA ATACCCAGGA TCGGATGGAT TCCTCTGAAA TCTACACCAA CACCTATGCA 
GCCGGGGGCA CGGTGGAAGG AGGTGTATCG GGAGTGGAGC TCAACACAGG TATGGGGACA 
GCCGTTGGCC TCATGGCCGC AGGGGCCGCA GGAGCCTCAG GGGCCGCAAG GAAGAGGAGC 
TCTACCATGG GAACCCTGCG GGACTACGCT GACGCAGACA TCAACATGGC TTTCTTGGAC 
AGCTACTTCT CGGAGAAAGC GTATGCTTAT GCAGATGAAG ATGAAGGTCG ACCAGCCAAT 
GACTGCTTGC TCATTTATGA CCACGAGGGA GTCGGGTCTC CCGTAGGCTC TATTGGTTGT 
TGCAGTTGGA TTGTGGATGA CTTAGATGAA AGCTGCATGG AAACTTTAGA TCCAAAATTT 
AGGACTCTTG CTGAGATCTG CTTAAACACA GAAATTGAAC CATTTCCTTC ACACCAGGCT 
TGTATACCAA TCAGTACTGA CCTCCCTTTG CTCGGACCTA ATTACTTTGT TAATGAATCT 
TCAGGATTGA CTCCCTCAGA AGTTGAATTC CAAGAAGAAA TGGCAGCATC TGAACCCGTG 
GTCCATGGGG ATATTATTGT GACTGAGACT TACGGTAATG CTGATCCATG TGTGCAACCC 
ACTACAATTA TTTTTGATCC TCAGCTTGCA CCCAATGTTG TAGTAACCGA AGCAGTAATG 
GCACCTGTCT ATGATATTCA AGGGAATATT TGTGTACCTG CTGAGTTAGC AGATTACAAC 
AATGTAATCT ATGCTGAGAG AGTACTGGCT AGTCCTGGTG TGCCTGACAT GAGCAATAGT 
AGCACGACTG AGGGTTGTAT GGGACCTGTG ATGAGCGGCA ATATTTTAGT AGGGCCAGAA 
ATTCAAGTGA TGCAAATGAT GAGTCCAGAC CTTCCCATAG GCCAAACCGT TGGCTCCACA 
TCCCCCATGA CATCTCGACA CAGAGTAACA CGATACAGTA ACATACATTA CACCCAACAG 
TAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_817123.1
CDS	136..3258
Translation	MDWLFFRNICLLIILMVVMEVNSEFIVEVKEFDIENGTTKWQTVRRQKREWIKFAAACREGEDNSKRNPIAKIRSDCESNQKITYRISGVGIDRPPYGVFTINPRTGEINITSVVDREITPLFLIYCRALNSRGEDLERPLELRVKVMDINDNAPVFSQSVYTASIEENSDANTLVVKLCATDADEENHLNSKIAYKIVSQEPSGAPMFILNRYTGEVCTMSSFLDREQHSMYNLVVRGSDRDGAADGLSSECDCRIKVLDVNDNFPTLEKTSYSASIEENCLSSELIRLQAIDLDEEGTDNWLAQYLILSGNDGNWFDIQTDPQTNEGILKVVKMLDYEQAPNIQLSIGVKNQADFHYSVASQFQMHPTPVRIQVVDVREGPAFHPSTMAFSVREGIKGSSLLNYVLGTYTAIDLDTGNPATDVRYIIGHDAGSWLKIDSRTGEIQFSREFDKKSKYIINGIYTAEILAIDDGSGKTATGTICIEVPDINDYCPNIFPERRTICIDSPSVLISVNEHSYGSPFTFCVVDEPPGIADMWDVRSTNATSAILTAKQVLSPGFYEIPILVKDSYNRACELAQMVQLYACDCDDNHMCLDSGAAGIYTEDITGDTYGPVTEDQAGVSNVGLGPAGIGMMVLGILLLILAPLLLLLCCCKQRQPEGLGTRFAPVPEGGEGVMQSWRIEGAHPEDRDVSNICAPMTASNTQDRMDSSEIYTNTYAAGGTVEGGVSGVELNTGMGTAVGLMAAGAAGASGAARKRSSTMGTLRDYADADINMAFLDSYFSEKAYAYADEDEGRPANDCLLIYDHEGVGSPVGSIGCCSWIVDDLDESCMETLDPKFRTLAEICLNTEIEPFPSHQACIPISTDLPLLGPNYFVNESSGLTPSEVEFQEEMAASEPVVHGDIIVTETYGNADPCVQPTTIIFDPQLAPNVVVTEAVMAPVYDIQGNICVPAELADYNNVIYAERVLASPGVPDMSNSSTTEGCMGPVMSGNILVGPEIQVMQMMSPDLPIGQTVGSTSPMTSRHRVTRYSNIHYTQQ

Target ORF information:

RefSeq Version	NM_177986.4
Organism	Homo sapiens(human)
Definition	Homo sapiens desmoglein 4 (DSG4), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_177986.4

ORF Insert Sequence:

ATGGATTGGC TCTTCTTCAG AAACATTTGC CTTTTGATCA TTCTAATGGT GGTGATGGAA 
GTAAACAGTG AATTTATTGT TGAGGTGAAG GAATTTGACA TTGAAAATGG CACTACAAAA 
TGGCAAACAG TCAGAAGACA AAAGCGGGAG TGGATCAAGT TTGCCGCAGC CTGTCGAGAA 
GGAGAGGACA ACTCGAAGAG GAACCCCATT GCCAAAATTC GATCAGACTG CGAATCGAAC 
CAGAAGATAA CATACCGGAT TTCTGGAGTA GGGATTGATC GACCACCATA TGGGGTATTC 
ACCATTAATC CTCGCACTGG GGAAATTAAC ATCACTTCAG TGGTAGACAG AGAAATAACT 
CCACTTTTCT TGATCTATTG CCGGGCTCTG AATTCACGGG GTGAAGATTT AGAAAGGCCT 
CTTGAGCTTA GAGTCAAAGT TATGGACATA AATGATAACG CTCCAGTCTT TTCGCAAAGT 
GTATACACAG CCAGCATTGA AGAAAATAGT GATGCCAATA CATTGGTAGT AAAGTTATGT 
GCCACAGATG CAGATGAAGA AAATCATCTG AATTCTAAAA TTGCCTACAA GATCGTCTCT 
CAGGAGCCAT CAGGTGCACC CATGTTCATT CTGAATAGGT ACACTGGAGA AGTCTGCACC 
ATGTCCAGTT TCTTGGACAG AGAGCAACAC AGTATGTACA ACCTGGTTGT GAGAGGCTCA 
GATCGGGATG GAGCTGCAGA TGGACTGTCT TCTGAGTGTG ACTGTAGAAT CAAGGTTTTA 
GACGTCAACG ATAATTTCCC CACCTTAGAG AAAACTTCAT ACTCAGCCAG TATTGAAGAG 
AATTGTTTAA GTTCGGAACT GATACGATTA CAAGCAATTG ATCTTGATGA AGAAGGCACT 
GATAACTGGT TGGCTCAATA TTTAATTCTC TCTGGAAATG ATGGGAATTG GTTCGATATT 
CAAACAGATC CACAAACCAA TGAAGGCATT TTGAAAGTTG TCAAGATGCT GGATTATGAA 
CAAGCACCTA ACATTCAGCT TAGTATCGGA GTTAAAAACC AAGCTGATTT TCACTACTCC 
GTTGCTTCTC AATTCCAAAT GCACCCAACC CCTGTGAGAA TTCAAGTTGT TGATGTGAGA 
GAAGGACCTG CATTTCATCC AAGTACTATG GCTTTTAGTG TGCGGGAAGG AATAAAAGGA 
AGTTCCTTAT TGAATTATGT GCTTGGCACA TATACAGCCA TAGATTTGGA CACAGGAAAC 
CCTGCAACAG ATGTCAGATA TATCATAGGG CATGATGCAG GCAGCTGGTT AAAAATTGAT 
TCAAGAACTG GTGAGATACA ATTTTCTAGA GAATTTGATA AGAAGTCAAA ATATATTATC 
AATGGGATAT ACACAGCAGA GATCCTGGCT ATAGATGATG GCTCTGGAAA AACAGCTACA 
GGAACCATAT GTATTGAGGT TCCTGATATC AATGATTATT GTCCAAACAT TTTTCCTGAA 
AGAAGAACCA TCTGCATTGA CTCTCCATCA GTCCTTATCT CTGTTAATGA ACATTCTTAT 
GGGTCTCCGT TTACTTTCTG TGTTGTTGAT GAGCCACCAG GAATAGCTGA CATGTGGGAT 
GTCAGATCAA CAAATGCTAC CTCGGCAATC CTTACGGCTA AGCAGGTTTT ATCTCCAGGA 
TTTTATGAAA TCCCAATCCT GGTGAAGGAC AGCTATAACA GAGCATGTGA ATTGGCACAA 
ATGGTGCAGT TATATGCCTG TGATTGCGAT GACAACCACA TGTGCCTGGA CTCTGGTGCC 
GCGGGCATCT ACACAGAGGA CATAACTGGT GACACGTATG GGCCTGTCAC TGAAGACCAA 
GCTGGAGTTT CAAATGTTGG TCTTGGACCA GCAGGGATTG GCATGATGGT TCTGGGCATC 
CTGCTACTGA TTTTGGCTCC ACTCTTGCTG CTCCTGTGTT GCTGCAAACA GAGACAGCCA 
GAAGGCCTGG GAACAAGATT TGCTCCTGTG CCTGAGGGCG GAGAAGGAGT GATGCAGTCT 
TGGAGAATTG AAGGGGCCCA TCCCGAGGAC AGGGATGTGT CAAATATATG TGCACCCATG 
ACAGCCTCAA ATACCCAGGA TCGGATGGAT TCCTCTGAAA TCTACACCAA CACCTATGCA 
GCCGGGGGCA CGGTGGAAGG AGGTGTATCG GGAGTGGAGC TCAACACAGG TATGGGGACA 
GCCGTTGGCC TCATGGCCGC AGGGGCCGCA GGAGCCTCAG GGGCCGCAAG GAAGAGGAGC 
TCTACCATGG GAACCCTGCG GGACTACGCT GACGCAGACA TCAACATGGC TTTCTTGGAC 
AGCTACTTCT CGGAGAAAGC GTATGCTTAT GCAGATGAAG ATGAAGGTCG ACCAGCCAAT 
GACTGCTTGC TCATTTATGA CCACGAGGGA GTCGGGTCTC CCGTAGGCTC TATTGGTTGT 
TGCAGTTGGA TTGTGGATGA CTTAGATGAA AGCTGCATGG AAACTTTAGA TCCAAAATTT 
AGGACTCTTG CTGAGATCTG CTTAAACACA GAAATTGAAC CATTTCCTTC ACACCAGGCT 
TGTATACCAA TCAGTACTGA CCTCCCTTTG CTCGGACCTA ATTACTTTGT TAATGAATCT 
TCAGGATTGA CTCCCTCAGA AGTTGAATTC CAAGAAGAAA TGGCAGCATC TGAACCCGTG 
GTCCATGGGG ATATTATTGT GACTGAGACT TACGGTAATG CTGATCCATG TGTGCAACCC 
ACTACAATTA TTTTTGATCC TCAGCTTGCA CCCAATGTTG TAGTAACCGA AGCAGTAATG 
GCACCTGTCT ATGATATTCA AGGGAATATT TGTGTACCTG CTGAGTTAGC AGATTACAAC 
AATGTAATCT ATGCTGAGAG AGTACTGGCT AGTCCTGGTG TGCCTGACAT GAGCAATAGT 
AGCACGACTG AGGGTTGTAT GGGACCTGTG ATGAGCGGCA ATATTTTAGT AGGGCCAGAA 
ATTCAAGTGA TGCAAATGAT GAGTCCAGAC CTTCCCATAG GCCAAACCGT TGGCTCCACA 
TCCCCCATGA CATCTCGACA CAGAGTAACA CGATACAGTA ACATACATTA CACCCAACAG 
TAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

DSG4 ( NM_001134453.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_001127925.1 Homo sapiens desmoglein 4 (DSG4), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu31898
Clone ID Related Accession (Same CDS sequence)	NM_001134453.2
Accession Version	NM_001134453.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 3180bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-08-04
Organism	Homo sapiens(human)
Product	desmoglein-4 isoform 1 precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AY177664.1, AY168788.1, BC132907.1, BC039098.1 and AC021549.9. On May 13, 2016 this sequence version replaced NM_001134453.1. Transcript Variant: This variant (1) lacks an alternate in-frame exon and uses an alternate in-frame splice site, both in the 3' coding region, compared to variant 2. The encoded isoform (1) is longer than isoform 2, but may undergo proteolytic processing similar to isoform 2. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AY168788.1, AY228236.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA2145893, SAMEA2147596 [ECO:0000350] ##Evidence-Data-END##

ATGGATTGGC TCTTCTTCAG AAACATTTGC CTTTTGATCA TTCTAATGGT GGTGATGGAA 
GTAAACAGTG AATTTATTGT TGAGGTGAAG GAATTTGACA TTGAAAATGG CACTACAAAA 
TGGCAAACAG TCAGAAGACA AAAGCGGGAG TGGATCAAGT TTGCCGCAGC CTGTCGAGAA 
GGAGAGGACA ACTCGAAGAG GAACCCCATT GCCAAAATTC GATCAGACTG CGAATCGAAC 
CAGAAGATAA CATACCGGAT TTCTGGAGTA GGGATTGATC GACCACCATA TGGGGTATTC 
ACCATTAATC CTCGCACTGG GGAAATTAAC ATCACTTCAG TGGTAGACAG AGAAATAACT 
CCACTTTTCT TGATCTATTG CCGGGCTCTG AATTCACGGG GTGAAGATTT AGAAAGGCCT 
CTTGAGCTTA GAGTCAAAGT TATGGACATA AATGATAACG CTCCAGTCTT TTCGCAAAGT 
GTATACACAG CCAGCATTGA AGAAAATAGT GATGCCAATA CATTGGTAGT AAAGTTATGT 
GCCACAGATG CAGATGAAGA AAATCATCTG AATTCTAAAA TTGCCTACAA GATCGTCTCT 
CAGGAGCCAT CAGGTGCACC CATGTTCATT CTGAATAGGT ACACTGGAGA AGTCTGCACC 
ATGTCCAGTT TCTTGGACAG AGAGCAACAC AGTATGTACA ACCTGGTTGT GAGAGGCTCA 
GATCGGGATG GAGCTGCAGA TGGACTGTCT TCTGAGTGTG ACTGTAGAAT CAAGGTTTTA 
GACGTCAACG ATAATTTCCC CACCTTAGAG AAAACTTCAT ACTCAGCCAG TATTGAAGAG 
AATTGTTTAA GTTCGGAACT GATACGATTA CAAGCAATTG ATCTTGATGA AGAAGGCACT 
GATAACTGGT TGGCTCAATA TTTAATTCTC TCTGGAAATG ATGGGAATTG GTTCGATATT 
CAAACAGATC CACAAACCAA TGAAGGCATT TTGAAAGTTG TCAAGATGCT GGATTATGAA 
CAAGCACCTA ACATTCAGCT TAGTATCGGA GTTAAAAACC AAGCTGATTT TCACTACTCC 
GTTGCTTCTC AATTCCAAAT GCACCCAACC CCTGTGAGAA TTCAAGTTGT TGATGTGAGA 
GAAGGACCTG CATTTCATCC AAGTACTATG GCTTTTAGTG TGCGGGAAGG AATAAAAGGA 
AGTTCCTTAT TGAATTATGT GCTTGGCACA TATACAGCCA TAGATTTGGA CACAGGAAAC 
CCTGCAACAG ATGTCAGATA TATCATAGGG CATGATGCAG GCAGCTGGTT AAAAATTGAT 
TCAAGAACTG GTGAGATACA ATTTTCTAGA GAATTTGATA AGAAGTCAAA ATATATTATC 
AATGGGATAT ACACAGCAGA GATCCTGGCT ATAGATGATG GCTCTGGAAA AACAGCTACA 
GGAACCATAT GTATTGAGGT TCCTGATATC AATGATTATT GTCCAAACAT TTTTCCTGAA 
AGAAGAACCA TCTGCATTGA CTCTCCATCA GTCCTTATCT CTGTTAATGA ACATTCTTAT 
GGGTCTCCGT TTACTTTCTG TGTTGTTGAT GAGCCACCAG GAATAGCTGA CATGTGGGAT 
GTCAGATCAA CAAATGCTAC CTCGGCAATC CTTACGGCTA AGCAGGTTTT ATCTCCAGGA 
TTTTATGAAA TCCCAATCCT GGTGAAGGAC AGCTATAACA GAGCATGTGA ATTGGCACAA 
ATGGTGCAGT TATATGCCTG TGATTGCGAT GACAACCACA TGTGCCTGGA CTCTGGTGCC 
GCGGGCATCT ACACAGAGGA CATAACTGGT GACACGTATG GGCCTGTCAC TGAAGACCAA 
GCTGGAGTTT CAAATGTTGG TCTTGGACCA GCAGGGATTG GCATGATGGT TCTGGGCATC 
CTGCTACTGA TTTTGGCTCC ACTCTTGCTG CTCCTGTGTT GCTGCAAACA GAGACAGCCA 
GAAGGCCTGG GAACAAGATT TGCTCCTGTG CCTGAGGGCG GAGAAGGAGT GATGCAGTCT 
TGGAGAATTG AAGGGGCCCA TCCCGAGGAC AGGCTTTTTA GCGCCTACGC CTTGCCGGGT 
GGTGGTGGCA CCGCAGACGG CGGCGGCAGC GTTTTAGGCA GATGCGCGCT GCAGGCAACT 
CCAGCGCTGT TAAACCAACA TCCTCCCTTT TCAGAAATCT ACACCAACAC CTATGCAGCC 
GGGGGCACGG TGGAAGGAGG TGTATCGGGA GTGGAGCTCA ACACAGGTAT GGGGACAGCC 
GTTGGCCTCA TGGCCGCAGG GGCCGCAGGA GCCTCAGGGG CCGCAAGGAA GAGGAGCTCT 
ACCATGGGAA CCCTGCGGGA CTACGCTGAC GCAGACATCA ACATGGCTTT CTTGGACAGC 
TACTTCTCGG AGAAAGCGTA TGCTTATGCA GATGAAGATG AAGGTCGACC AGCCAATGAC 
TGCTTGCTCA TTTATGACCA CGAGGGAGTC GGGTCTCCCG TAGGCTCTAT TGGTTGTTGC 
AGTTGGATTG TGGATGACTT AGATGAAAGC TGCATGGAAA CTTTAGATCC AAAATTTAGG 
ACTCTTGCTG AGATCTGCTT AAACACAGAA ATTGAACCAT TTCCTTCACA CCAGGCTTGT 
ATACCAATCA GTACTGACCT CCCTTTGCTC GGACCTAATT ACTTTGTTAA TGAATCTTCA 
GGATTGACTC CCTCAGAAGT TGAATTCCAA GAAGAAATGG CAGCATCTGA ACCCGTGGTC 
CATGGGGATA TTATTGTGAC TGAGACTTAC GGTAATGCTG ATCCATGTGT GCAACCCACT 
ACAATTATTT TTGATCCTCA GCTTGCACCC AATGTTGTAG TAACCGAAGC AGTAATGGCA 
CCTGTCTATG ATATTCAAGG GAATATTTGT GTACCTGCTG AGTTAGCAGA TTACAACAAT 
GTAATCTATG CTGAGAGAGT ACTGGCTAGT CCTGGTGTGC CTGACATGAG CAATAGTAGC 
ACGACTGAGG GTTGTATGGG ACCTGTGATG AGCGGCAATA TTTTAGTAGG GCCAGAAATT 
CAAGTGATGC AAATGATGAG TCCAGACCTT CCCATAGGCC AAACCGTTGG CTCCACATCC 
CCCATGACAT CTCGACACAG AGTAACACGA TACAGTAACA TACATTACAC CCAACAGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001127925.1
CDS	136..3315
Translation	MDWLFFRNICLLIILMVVMEVNSEFIVEVKEFDIENGTTKWQTVRRQKREWIKFAAACREGEDNSKRNPIAKIRSDCESNQKITYRISGVGIDRPPYGVFTINPRTGEINITSVVDREITPLFLIYCRALNSRGEDLERPLELRVKVMDINDNAPVFSQSVYTASIEENSDANTLVVKLCATDADEENHLNSKIAYKIVSQEPSGAPMFILNRYTGEVCTMSSFLDREQHSMYNLVVRGSDRDGAADGLSSECDCRIKVLDVNDNFPTLEKTSYSASIEENCLSSELIRLQAIDLDEEGTDNWLAQYLILSGNDGNWFDIQTDPQTNEGILKVVKMLDYEQAPNIQLSIGVKNQADFHYSVASQFQMHPTPVRIQVVDVREGPAFHPSTMAFSVREGIKGSSLLNYVLGTYTAIDLDTGNPATDVRYIIGHDAGSWLKIDSRTGEIQFSREFDKKSKYIINGIYTAEILAIDDGSGKTATGTICIEVPDINDYCPNIFPERRTICIDSPSVLISVNEHSYGSPFTFCVVDEPPGIADMWDVRSTNATSAILTAKQVLSPGFYEIPILVKDSYNRACELAQMVQLYACDCDDNHMCLDSGAAGIYTEDITGDTYGPVTEDQAGVSNVGLGPAGIGMMVLGILLLILAPLLLLLCCCKQRQPEGLGTRFAPVPEGGEGVMQSWRIEGAHPEDRLFSAYALPGGGGTADGGGSVLGRCALQATPALLNQHPPFSEIYTNTYAAGGTVEGGVSGVELNTGMGTAVGLMAAGAAGASGAARKRSSTMGTLRDYADADINMAFLDSYFSEKAYAYADEDEGRPANDCLLIYDHEGVGSPVGSIGCCSWIVDDLDESCMETLDPKFRTLAEICLNTEIEPFPSHQACIPISTDLPLLGPNYFVNESSGLTPSEVEFQEEMAASEPVVHGDIIVTETYGNADPCVQPTTIIFDPQLAPNVVVTEAVMAPVYDIQGNICVPAELADYNNVIYAERVLASPGVPDMSNSSTTEGCMGPVMSGNILVGPEIQVMQMMSPDLPIGQTVGSTSPMTSRHRVTRYSNIHYTQQ

Target ORF information:

RefSeq Version	NM_001134453.2
Organism	Homo sapiens(human)
Definition	Homo sapiens desmoglein 4 (DSG4), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001134453.2

ORF Insert Sequence:

ATGGATTGGC TCTTCTTCAG AAACATTTGC CTTTTGATCA TTCTAATGGT GGTGATGGAA 
GTAAACAGTG AATTTATTGT TGAGGTGAAG GAATTTGACA TTGAAAATGG CACTACAAAA 
TGGCAAACAG TCAGAAGACA AAAGCGGGAG TGGATCAAGT TTGCCGCAGC CTGTCGAGAA 
GGAGAGGACA ACTCGAAGAG GAACCCCATT GCCAAAATTC GATCAGACTG CGAATCGAAC 
CAGAAGATAA CATACCGGAT TTCTGGAGTA GGGATTGATC GACCACCATA TGGGGTATTC 
ACCATTAATC CTCGCACTGG GGAAATTAAC ATCACTTCAG TGGTAGACAG AGAAATAACT 
CCACTTTTCT TGATCTATTG CCGGGCTCTG AATTCACGGG GTGAAGATTT AGAAAGGCCT 
CTTGAGCTTA GAGTCAAAGT TATGGACATA AATGATAACG CTCCAGTCTT TTCGCAAAGT 
GTATACACAG CCAGCATTGA AGAAAATAGT GATGCCAATA CATTGGTAGT AAAGTTATGT 
GCCACAGATG CAGATGAAGA AAATCATCTG AATTCTAAAA TTGCCTACAA GATCGTCTCT 
CAGGAGCCAT CAGGTGCACC CATGTTCATT CTGAATAGGT ACACTGGAGA AGTCTGCACC 
ATGTCCAGTT TCTTGGACAG AGAGCAACAC AGTATGTACA ACCTGGTTGT GAGAGGCTCA 
GATCGGGATG GAGCTGCAGA TGGACTGTCT TCTGAGTGTG ACTGTAGAAT CAAGGTTTTA 
GACGTCAACG ATAATTTCCC CACCTTAGAG AAAACTTCAT ACTCAGCCAG TATTGAAGAG 
AATTGTTTAA GTTCGGAACT GATACGATTA CAAGCAATTG ATCTTGATGA AGAAGGCACT 
GATAACTGGT TGGCTCAATA TTTAATTCTC TCTGGAAATG ATGGGAATTG GTTCGATATT 
CAAACAGATC CACAAACCAA TGAAGGCATT TTGAAAGTTG TCAAGATGCT GGATTATGAA 
CAAGCACCTA ACATTCAGCT TAGTATCGGA GTTAAAAACC AAGCTGATTT TCACTACTCC 
GTTGCTTCTC AATTCCAAAT GCACCCAACC CCTGTGAGAA TTCAAGTTGT TGATGTGAGA 
GAAGGACCTG CATTTCATCC AAGTACTATG GCTTTTAGTG TGCGGGAAGG AATAAAAGGA 
AGTTCCTTAT TGAATTATGT GCTTGGCACA TATACAGCCA TAGATTTGGA CACAGGAAAC 
CCTGCAACAG ATGTCAGATA TATCATAGGG CATGATGCAG GCAGCTGGTT AAAAATTGAT 
TCAAGAACTG GTGAGATACA ATTTTCTAGA GAATTTGATA AGAAGTCAAA ATATATTATC 
AATGGGATAT ACACAGCAGA GATCCTGGCT ATAGATGATG GCTCTGGAAA AACAGCTACA 
GGAACCATAT GTATTGAGGT TCCTGATATC AATGATTATT GTCCAAACAT TTTTCCTGAA 
AGAAGAACCA TCTGCATTGA CTCTCCATCA GTCCTTATCT CTGTTAATGA ACATTCTTAT 
GGGTCTCCGT TTACTTTCTG TGTTGTTGAT GAGCCACCAG GAATAGCTGA CATGTGGGAT 
GTCAGATCAA CAAATGCTAC CTCGGCAATC CTTACGGCTA AGCAGGTTTT ATCTCCAGGA 
TTTTATGAAA TCCCAATCCT GGTGAAGGAC AGCTATAACA GAGCATGTGA ATTGGCACAA 
ATGGTGCAGT TATATGCCTG TGATTGCGAT GACAACCACA TGTGCCTGGA CTCTGGTGCC 
GCGGGCATCT ACACAGAGGA CATAACTGGT GACACGTATG GGCCTGTCAC TGAAGACCAA 
GCTGGAGTTT CAAATGTTGG TCTTGGACCA GCAGGGATTG GCATGATGGT TCTGGGCATC 
CTGCTACTGA TTTTGGCTCC ACTCTTGCTG CTCCTGTGTT GCTGCAAACA GAGACAGCCA 
GAAGGCCTGG GAACAAGATT TGCTCCTGTG CCTGAGGGCG GAGAAGGAGT GATGCAGTCT 
TGGAGAATTG AAGGGGCCCA TCCCGAGGAC AGGCTTTTTA GCGCCTACGC CTTGCCGGGT 
GGTGGTGGCA CCGCAGACGG CGGCGGCAGC GTTTTAGGCA GATGCGCGCT GCAGGCAACT 
CCAGCGCTGT TAAACCAACA TCCTCCCTTT TCAGAAATCT ACACCAACAC CTATGCAGCC 
GGGGGCACGG TGGAAGGAGG TGTATCGGGA GTGGAGCTCA ACACAGGTAT GGGGACAGCC 
GTTGGCCTCA TGGCCGCAGG GGCCGCAGGA GCCTCAGGGG CCGCAAGGAA GAGGAGCTCT 
ACCATGGGAA CCCTGCGGGA CTACGCTGAC GCAGACATCA ACATGGCTTT CTTGGACAGC 
TACTTCTCGG AGAAAGCGTA TGCTTATGCA GATGAAGATG AAGGTCGACC AGCCAATGAC 
TGCTTGCTCA TTTATGACCA CGAGGGAGTC GGGTCTCCCG TAGGCTCTAT TGGTTGTTGC 
AGTTGGATTG TGGATGACTT AGATGAAAGC TGCATGGAAA CTTTAGATCC AAAATTTAGG 
ACTCTTGCTG AGATCTGCTT AAACACAGAA ATTGAACCAT TTCCTTCACA CCAGGCTTGT 
ATACCAATCA GTACTGACCT CCCTTTGCTC GGACCTAATT ACTTTGTTAA TGAATCTTCA 
GGATTGACTC CCTCAGAAGT TGAATTCCAA GAAGAAATGG CAGCATCTGA ACCCGTGGTC 
CATGGGGATA TTATTGTGAC TGAGACTTAC GGTAATGCTG ATCCATGTGT GCAACCCACT 
ACAATTATTT TTGATCCTCA GCTTGCACCC AATGTTGTAG TAACCGAAGC AGTAATGGCA 
CCTGTCTATG ATATTCAAGG GAATATTTGT GTACCTGCTG AGTTAGCAGA TTACAACAAT 
GTAATCTATG CTGAGAGAGT ACTGGCTAGT CCTGGTGTGC CTGACATGAG CAATAGTAGC 
ACGACTGAGG GTTGTATGGG ACCTGTGATG AGCGGCAATA TTTTAGTAGG GCCAGAAATT 
CAAGTGATGC AAATGATGAG TCCAGACCTT CCCATAGGCC AAACCGTTGG CTCCACATCC 
CCCATGACAT CTCGACACAG AGTAACACGA TACAGTAACA TACATTACAC CCAACAGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Novel D323G mutation of DSG4 gene in a girl with localized autosomal recessive hypotrichosis clinically overlapped with monilethrix.
International journal of dermatology54(10)1163-8(2015 Oct)
Wang JM,Xiao YJ,Liang YH

An autosomal recessive mutation of DSG4 causes monilethrix through the ER stress response.
The Journal of investigative dermatology135(5)1253-1260(2015 May)
Kato M,Shimizu A,Yokoyama Y,Kaira K,Shimomura Y,Ishida-Yamamoto A,Kamei K,Tokunaga F,Ishikawa O

A novel deletion mutation in the DSG4 gene underlies autosomal recessive hypotrichosis with variable phenotype in two unrelated consanguineous families.
Clinical and experimental dermatology40(1)78-84(2015 Jan)
Ullah A,Raza SI,Ali RH,Naveed AK,Jan A,Rizvi SD,Satti R,Ahmad W

Desmoglein as a target in skin disease and beyond.
The Journal of investigative dermatology132(3 Pt 2)776-84(2012 Mar)
Amagai M,Stanley JR

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DSG4 cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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