Gene Symbol | PARP4 |
Entrez Gene ID | 143 |
Full Name | poly(ADP-ribose) polymerase family member 4 |
Synonyms | ADPRTL1,ARTD4,PARP-4,PARPL,PH5P,VAULT3,VPARP,VWA5C,p193 |
General protein information |
|
Gene Type | protein-coding |
Organism | Homo sapiens(human) |
Genome | |
Summary | This gene encodes poly(ADP-ribosyl)transferase-like 1 protein, which is capable of catalyzing a poly(ADP-ribosyl)ation reaction. This protein has a catalytic domain which is homologous to that of poly (ADP-ribosyl) transferase, but lacks an N-terminal DNA binding domain which activates the C-terminal catalytic domain of poly (ADP-ribosyl) transferase. Since this protein is not capable of binding DNA directly, its transferase activity may be activated by other factors such as protein-protein interaction mediated by the extensive carboxyl terminus. [provided by RefSeq, Jul 2008]. |
Disorder MIM: |