ACSM6 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	ACSM6
Entrez Gene ID	142827
Full Name	acyl-CoA synthetase medium chain family member 6
Synonyms	C10orf129,bA310E22.3
General protein information	Preferred Names acyl-CoA synthetase medium chain family member 6 Names acyl-coenzyme A synthetase ACSM6, mitochondrial AMP-binding enzyme
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 10 Map Location: 10q23.33

mRNA and Protein(s)

mRNA	Protein	Name
NM_207321.2	NP_997204.2	acyl-coenzyme A synthetase ACSM6, mitochondrial precursor

Pathways from BioSystems

Homologies

Homo sapiens (human)	C10orf129	NP_997204.2
Pan troglodytes (chimpanzee)	C10H10orf129	XP_001144196.2

Gene Ontology
Bibliography

Related articles in PubMed

High-content genome-wide RNAi screens identify regulators of parkin upstream of mitophagy.
Hasson SA, Kane LA, Yamano K, Huang CH, Sliter DA, Buehler E, Wang C, Heman-Ackah SM, Hessa T, Guha R, Martin SE, Youle RJ
Nature504(7479)291-5(2013 Dec)

An integrated clinico-metabolomic model improves prediction of death in sepsis.
Langley RJ, Tsalik EL, van Velkinburgh JC, Glickman SW, Rice BJ, Wang C, Chen B, Carin L, Suarez A, Mohney RP, Freeman DH, Wang M, You J, Wulff J, Thompson JW, Moseley MA, Reisinger S, Edmonds BT, Grinnell B, Nelson DR, Dinwiddie DL, Miller NA, Saunders CJ, Soden SS, Rogers AJ, Gazourian L, Fredenburgh LE, Massaro AF, Baron RM, Choi AM, Corey GR, Ginsburg GS, Cairns CB, Otero RM, Fowler VG Jr, Rivers EP, Woods CW, Kingsmore SF
Science translational medicine5(195)195ra95(2013 Jul)

A scan of chromosome 10 identifies a novel locus showing strong association with late-onset Alzheimer disease.
Grupe A, Li Y, Rowland C, Nowotny P, Hinrichs AL, Smemo S, Kauwe JS, Maxwell TJ, Cherny S, Doil L, Tacey K, van Luchene R, Myers A, Wavrant-De Vri?ze F, Kaleem M, Hollingworth P, Jehu L, Foy C, Archer N, Hamilton G, Holmans P, Morris CM, Catanese J, Sninsky J, White TJ, Powell J, Hardy J, O'Donovan M, Lovestone S, Jones L, Morris JC, Thal L, Owen M, Williams J, Goate A
American journal of human genetics78(1)78-88(2006 Jan)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Observational study of gene-disease association. (HuGE Navigator)
Title: A scan of chromosome 10 identifies a novel locus showing strong association with late-onset Alzheimer disease.

The following ACSM6 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the ACSM6 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OHu27790	NM_207321.2 Latest version!	Homo sapiens acyl-CoA synthetase medium chain family member 6 (ACSM6), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$223.30 $319.00

ORF Online Only Promotion

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

ACSM6 ( NM_207321.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_997204.2 Homo sapiens acyl-CoA synthetase medium chain family member 6 (ACSM6), mRNA.

Price & Availability↑

CloneID	OHu27790
Clone ID Related Accession (Same CDS sequence)	NM_207321.2
Accession Version	NM_207321.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1443bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-27
Organism	Homo sapiens(human)
Product	acyl-coenzyme A synthetase ACSM6, mitochondrial precursor
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AK126134.1, BC104211.2 and BC063654.1. On Aug 7, 2008 this sequence version replaced NM_207321.1. ##Evidence-Data-START## RNAseq introns :: mixed/partial sample support SAMEA1968968, SAMEA2142586 [ECO:0000350] ##Evidence-Data-END## ##RefSeq-Attributes-START## RefSeq Select criteria :: based on single protein-coding transcript ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGCTAGGCC GATTTCAACC CTTCTCCTTG GTCCGGAGTT TCAGACTGGG ATTTGAAGCC 
TGCTGCTATC CAAACCAAAA ATGTGCTACT CAGACCATCA GACCCCCTGA CTCCAGGTGC 
CTAGTCCAAG CAGTTTCTCA GAACTTTAAT TTTGCAAAGG ATGTGTTGGA TCAGTGGTCC 
CAGCTGGAAA AGGACGGACT CAGAGGGCCT TACCCCGCCC TCTGGAAGGT TAGTGCCAAA 
GGAGAAGAGG ACAAATGGAG CTTTGAAAGG ATGACTCAAC TCTCCAAGAA GGCCGCCAGC 
ATCCTCTCAG ACACCTGTGC CCTTAGCCAT GGAGACCGGC TGATGATAAT CTTGCCCCCA 
ACACCTGAAG CCTACTGGAT CTGCCTGGCC TGTGTGCGCT TGGGAATCAC CTTTGTGCCT 
GGGAGCCCCC AGCTGACTGC CAAGAAAATT CGCTATCAAT TACGCATGTC TAAGGCCCAG 
TGCATTGTGG CTAATGAAGC TATGGCCCCA GTTGTAAACT CTGCCGTGTC CGACTGCCCC 
ACCTTGAAAA CCAAGCTCCT GGTGTCAGAT AAGAGCTATG ATGGGTGGTT GGATTTCAAG 
AAGTTGATTC AAGTTGCCCC TCCAAAGCAG ACCTACATGA GGACCAAAAG CCAAGATCCA 
ATGGCCATAT TCTTCACCAA GGGTACAACA GGAGCTCCCA AAATGGTCGA GTATTCCCAG 
TATGGTTTGG GAATGGGATT CAGCCAGGCT TCCAGACGGT GGATGGATCT CCAGCCAACA 
GATGTCTTGT GGAGTCTGGG TGATGCCTTT GGTGGATCTT TATCCCTGAG CGCTGTCTTG 
GGAACTTGGT TCCAAGGAGC CTGTGTGTTT CTGTGTCACA TGCCAACCTT CTGCCCTGAG 
ACTGTTCTAA ATGTCCTGTC CAGATTTCCC ATCACCACTC TATCTGCAAA TCCAGAGATG 
TACCAGGAAC TGCTTCAGCA CAAGTGTTTC ACCAGCTACA GATTCAAGAG TCTGAAGCAG 
TGTGTGGCTG CAGGAGGACC CATCAGCCCT GGGGTGATTG AGGACTGGAA ACGCATCACT 
AAGTTGGACA TCTATGAAGG CTATGGGCAG ACGGAAACTG GTCTACTCTG TGCCACTTCC 
AAAACAATAA AATTGAAGCC AAGCTCTCTG GGGAAGCCAT TGCCACCTTA TATTGTCCAG 
ATTGTGGATG AAAACTCAAA TCTCCTGCCT CCAGGGGAAG AAGGAAATAT TGCAATCCGC 
ATAAAACTAA ACCAACCTGC TTCTCTGTAC TGTCCACACA TGGTGAGCTG GGAGGAATAT 
GCTTCAGCAA GAGGCCACAT GCTTTACCTC ACAGGTGACA GAGGGATCAT GGATGAAGAC 
GGCTACTTCT GGTGGTCTGG TAGAGTTGAT GATGTTGCCA ATGCATTGGG TCAGAGATTG 
TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_997204.2
CDS	126..1568
Translation	MLGRFQPFSLVRSFRLGFEACCYPNQKCATQTIRPPDSRCLVQAVSQNFNFAKDVLDQWSQLEKDGLRGPYPALWKVSAKGEEDKWSFERMTQLSKKAASILSDTCALSHGDRLMIILPPTPEAYWICLACVRLGITFVPGSPQLTAKKIRYQLRMSKAQCIVANEAMAPVVNSAVSDCPTLKTKLLVSDKSYDGWLDFKKLIQVAPPKQTYMRTKSQDPMAIFFTKGTTGAPKMVEYSQYGLGMGFSQASRRWMDLQPTDVLWSLGDAFGGSLSLSAVLGTWFQGACVFLCHMPTFCPETVLNVLSRFPITTLSANPEMYQELLQHKCFTSYRFKSLKQCVAAGGPISPGVIEDWKRITKLDIYEGYGQTETGLLCATSKTIKLKPSSLGKPLPPYIVQIVDENSNLLPPGEEGNIAIRIKLNQPASLYCPHMVSWEEYASARGHMLYLTGDRGIMDEDGYFWWSGRVDDVANALGQRL

Target ORF information:

RefSeq Version	NM_207321.2
Organism	Homo sapiens(human)
Definition	Homo sapiens acyl-CoA synthetase medium chain family member 6 (ACSM6), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_207321.2

ORF Insert Sequence:

ATGCTAGGCC GATTTCAACC CTTCTCCTTG GTCCGGAGTT TCAGACTGGG ATTTGAAGCC 
TGCTGCTATC CAAACCAAAA ATGTGCTACT CAGACCATCA GACCCCCTGA CTCCAGGTGC 
CTAGTCCAAG CAGTTTCTCA GAACTTTAAT TTTGCAAAGG ATGTGTTGGA TCAGTGGTCC 
CAGCTGGAAA AGGACGGACT CAGAGGGCCT TACCCCGCCC TCTGGAAGGT TAGTGCCAAA 
GGAGAAGAGG ACAAATGGAG CTTTGAAAGG ATGACTCAAC TCTCCAAGAA GGCCGCCAGC 
ATCCTCTCAG ACACCTGTGC CCTTAGCCAT GGAGACCGGC TGATGATAAT CTTGCCCCCA 
ACACCTGAAG CCTACTGGAT CTGCCTGGCC TGTGTGCGCT TGGGAATCAC CTTTGTGCCT 
GGGAGCCCCC AGCTGACTGC CAAGAAAATT CGCTATCAAT TACGCATGTC TAAGGCCCAG 
TGCATTGTGG CTAATGAAGC TATGGCCCCA GTTGTAAACT CTGCCGTGTC CGACTGCCCC 
ACCTTGAAAA CCAAGCTCCT GGTGTCAGAT AAGAGCTATG ATGGGTGGTT GGATTTCAAG 
AAGTTGATTC AAGTTGCCCC TCCAAAGCAG ACCTACATGA GGACCAAAAG CCAAGATCCA 
ATGGCCATAT TCTTCACCAA GGGTACAACA GGAGCTCCCA AAATGGTCGA GTATTCCCAG 
TATGGTTTGG GAATGGGATT CAGCCAGGCT TCCAGACGGT GGATGGATCT CCAGCCAACA 
GATGTCTTGT GGAGTCTGGG TGATGCCTTT GGTGGATCTT TATCCCTGAG CGCTGTCTTG 
GGAACTTGGT TCCAAGGAGC CTGTGTGTTT CTGTGTCACA TGCCAACCTT CTGCCCTGAG 
ACTGTTCTAA ATGTCCTGTC CAGATTTCCC ATCACCACTC TATCTGCAAA TCCAGAGATG 
TACCAGGAAC TGCTTCAGCA CAAGTGTTTC ACCAGCTACA GATTCAAGAG TCTGAAGCAG 
TGTGTGGCTG CAGGAGGACC CATCAGCCCT GGGGTGATTG AGGACTGGAA ACGCATCACT 
AAGTTGGACA TCTATGAAGG CTATGGGCAG ACGGAAACTG GTCTACTCTG TGCCACTTCC 
AAAACAATAA AATTGAAGCC AAGCTCTCTG GGGAAGCCAT TGCCACCTTA TATTGTCCAG 
ATTGTGGATG AAAACTCAAA TCTCCTGCCT CCAGGGGAAG AAGGAAATAT TGCAATCCGC 
ATAAAACTAA ACCAACCTGC TTCTCTGTAC TGTCCACACA TGGTGAGCTG GGAGGAATAT 
GCTTCAGCAA GAGGCCACAT GCTTTACCTC ACAGGTGACA GAGGGATCAT GGATGAAGAC 
GGCTACTTCT GGTGGTCTGG TAGAGTTGAT GATGTTGCCA ATGCATTGGG TCAGAGATTG 
TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

High-content genome-wide RNAi screens identify regulators of parkin upstream of mitophagy.
Nature504(7479)291-5(2013 Dec)
Hasson SA,Kane LA,Yamano K,Huang CH,Sliter DA,Buehler E,Wang C,Heman-Ackah SM,Hessa T,Guha R,Martin SE,Youle RJ

An integrated clinico-metabolomic model improves prediction of death in sepsis.
Science translational medicine5(195)195ra95(2013 Jul)
Langley RJ,Tsalik EL,van Velkinburgh JC,Glickman SW,Rice BJ,Wang C,Chen B,Carin L,Suarez A,Mohney RP,Freeman DH,Wang M,You J,Wulff J,Thompson JW,Moseley MA,Reisinger S,Edmonds BT,Grinnell B,Nelson DR,Dinwiddie DL,Miller NA,Saunders CJ,Soden SS,Rogers AJ,Gazourian L,Fredenburgh LE,Massaro AF,Baron RM,Choi AM,Corey GR,Ginsburg GS,Cairns CB,Otero RM,Fowler VG Jr,Rivers EP,Woods CW,Kingsmore SF

A scan of chromosome 10 identifies a novel locus showing strong association with late-onset Alzheimer disease.
American journal of human genetics78(1)78-88(2006 Jan)
Grupe A,Li Y,Rowland C,Nowotny P,Hinrichs AL,Smemo S,Kauwe JS,Maxwell TJ,Cherny S,Doil L,Tacey K,van Luchene R,Myers A,Wavrant-De Vri?ze F,Kaleem M,Hollingworth P,Jehu L,Foy C,Archer N,Hamilton G,Holmans P,Morris CM,Catanese J,Sninsky J,White TJ,Powell J,Hardy J,O'Donovan M,Lovestone S,Jones L,Morris JC,Thal L,Owen M,Williams J,Goate A

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ACSM6 cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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