Gene Symbol | ZNF280B |
Entrez Gene ID | 140883 |
Full Name | zinc finger protein 280B |
Synonyms | 5'OY11.1,D87009.C22.3,SUHW2,ZNF279,ZNF632 |
General protein information |
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Gene Type | protein-coding |
Organism | Homo sapiens(human) |
Genome | |
Summary | The protein encoded by this gene is a transcription factor that upregulates expression of MDM2, which negatively regulates p53 expression. This gene is highly expressed in prostate cancer cells, which leads to a reduction in p53 levels and an increase in growth of the cancer cells. Several transcript variants have been found for this gene, but only one of them is protein-coding. [provided by RefSeq, Jan 2015]. |