PIH1D3 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	PIH1D3
Entrez Gene ID	139212
Full Name	PIH1 domain containing 3
Synonyms	CILD36,CXorf41,NYSAR97
General protein information	Preferred Names PIH1 domain containing 3 Names protein PIH1D3 PIH1 domain-containing protein 3 sarcoma antigen NY-SAR-97
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: X Map Location: Xq22.3
Disorder MIM:	300933
Disorder Html:	Ciliary dyskinesia, primary, 36, X-linked, 300991 (3)

mRNA and Protein(s)

mRNA	Protein	Name
XM_011530855.1	XP_011529157.1	protein PIH1D3 isoform X1
NM_173494.2	NP_775765.1	protein PIH1D3
XM_011530855.2	XP_011529157.1	protein PIH1D3 isoform X1
NM_001169154.1	NP_001162625.1	protein PIH1D3
NM_173494.1	NP_775765.1	protein PIH1D3

Pathways from BioSystems

Homologies

Mus musculus (house mouse)	Pih1d3	NP_083338.1
Drosophila melanogaster (fruit fly)	CG5048	NP_648712.1
Pan troglodytes (chimpanzee)	PIH1D3	XP_521211.3
Rattus norvegicus (Norway rat)	Pih1d3	NP_001020061.1
Gallus gallus (chicken)	C4HXORF41	XP_420180.2
Danio rerio (zebrafish)	pih1d3	NP_001002309.1
Xenopus tropicalis (tropical clawed frog)	pih1d3	XP_002939244.1
Homo sapiens (human)	PIH1D3	NP_001162625.1
	PIH1D3	XP_001094814.1
Mus musculus (house mouse)	E230019M04Rik	NP_808589.1
Canis lupus familiaris (dog)	PIH1D3	XP_549174.3
Bos taurus (cattle)	PIH1D3	NP_001039494.1

Gene Ontology
Bibliography

Related articles in PubMed

X-linked primary ciliary dyskinesia due to mutations in the cytoplasmic axonemal dynein assembly factor PIH1D3.
Olcese C, Patel MP, Shoemark A, Kiviluoto S, Legendre M, Williams HJ, Vaughan CK, Hayward J, Goldenberg A, Emes RD, Munye MM, Dyer L, Cahill T, Bevillard J, Gehrig C, Guipponi M, Chantot S, Duquesnoy P, Thomas L, Jeanson L, Copin B, Tamalet A, Thauvin-Robinet C, Papon JF, Garin A, Pin I, Vera G, Aurora P, Fassad MR, Jenkins L, Boustred C, Cullup T, Dixon M, Onoufriadis A, Bush A, Chung EM, Antonarakis SE, Loebinger MR, Wilson R, Armengot M, Escudier E, Hogg C, , Amselem S, Sun Z, Bartoloni L, Blouin JL, Mitchison HM
Nature communications814279(2017 Feb)

Mutations in PIH1D3 Cause X-Linked Primary Ciliary Dyskinesia with Outer and Inner Dynein Arm Defects.
Paff T, Loges NT, Aprea I, Wu K, Bakey Z, Haarman EG, Daniels JMA, Sistermans EA, Bogunovic N, Dougherty GW, H?ben IM, Gro?e-Onnebrink J, Matter A, Olbrich H, Werner C, Pals G, Schmidts M, Omran H, Micha D
American journal of human genetics100(1)160-168(2017 Jan)

Pih1d3 is required for cytoplasmic preassembly of axonemal dynein in mouse sperm.
Dong F, Shinohara K, Botilde Y, Nabeshima R, Asai Y, Fukumoto A, Hasegawa T, Matsuo M, Takeda H, Shiratori H, Nakamura T, Hamada H
The Journal of cell biology204(2)203-13(2014 Jan)

Immunomic analysis of human sarcoma.
Lee SY, Obata Y, Yoshida M, Stockert E, Williamson B, Jungbluth AA, Chen YT, Old LJ, Scanlan MJ
Proceedings of the National Academy of Sciences of the United States of America100(5)2651-6(2003 Mar)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Mutations in PIH1D3 Cause X-Linked Primary Ciliary Dyskinesia with Outer and Inner Dynein Arm Defects
Title: Mutations in PIH1D3 Cause X-Linked Primary Ciliary Dyskinesia with Outer and Inner Dynein Arm Defects.

The following PIH1D3 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the PIH1D3 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu22203	NM_001169154.1 Latest version!	Homo sapiens dynein axonemal assembly factor 6 (DNAAF6), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
OHu22203	NM_173494.2 Latest version!	Homo sapiens dynein axonemal assembly factor 6 (DNAAF6), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
OHu22203	XM_011530855.2 Latest version!	Homo sapiens PIH1 domain containing 3 (PIH1D3), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
View Old Accession Versions >>
OHu22203	XM_011530855.1	Homo sapiens PIH1 domain containing 3 (PIH1D3), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
OHu22203	NM_173494.1	Homo sapiens PIH1 domain containing 3 (PIH1D3), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
Hide Old Accession Versions >>

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

PIH1D3 ( NM_173494.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_775765.1 Homo sapiens dynein axonemal assembly factor 6 (DNAAF6), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu22203
Clone ID Related Accession (Same CDS sequence)	XM_011530855.1 , NM_173494.2 , XM_011530855.2 , NM_001169154.1 , NM_173494.1
Accession Version	NM_173494.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 645bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-19
Organism	Homo sapiens(human)
Product	protein PIH1D3
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AL136112.10 and BC033510.1. This sequence is a reference standard in the RefSeqGene project. On Jun 2, 2019 this sequence version replaced NM_173494.1. Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 1. Both variants 1 and 2 encode the same protein. ##Evidence-Data-START## Transcript exon combination :: BC033510.1, SRR7410570.693163.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968968, SAMEA2144333 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## RefSeq Select criteria :: based on manual assertion, conservation, expression, longest protein ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGGAATCTG AAAATATGGA TTCTGAAAAT ATGAAGACAG AAAATATGGA ATCTCAAAAT 
GTAGACTTTG AGAGTGTTTC TTCAGTTACA GCTCTGGAAG CCCTCTCTAA GCTACTTAAT 
CCTGAAGAAG AGGATGATTC TGACTATGGA CAGACAAATG GTTTATCTAC TATTGGAGCC 
ATGGGTCCTG GGAATATTGG ACCACCCCAA ATAGAAGAGC TCAAAGTCAT CCCTGAAACC 
AGCGAGGAAA ATAATGAGGA CATCTGGAAT TCAGAAGAGA TTCCAGAAGG AGCAGAATAT 
GATGATATGT GGGATGTTAG AGAAATCCCA GAGTATGAGA TTATATTCAG ACAGCAGGTG 
GGAACTGAAG ATATATTTTT AGGGTTGTCA AAAAAGGACT CCTCAACAGG TTGTTGCAGT 
GAACTAGTGG CTAAAATTAA ATTGCCAAAT ACAAACCCTT CTGATATTCA AATTGATATC 
CAGGAAACAA TCCTTGACCT TCGTACTCCT CAGAAGAAGC TGTTGATAAC TCTTCCTGAG 
CTGGTGGAAT GTACCAGTGC CAAAGCATTC TATATCCCAG AGACTGAAAC TCTTGAAATC 
ACTATGACTA TGAAAAGAGA GTTAGATATT GCTAATTTCT TCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_775765.1
CDS	84..728
Translation	MESENMDSENMKTENMESQNVDFESVSSVTALEALSKLLNPEEEDDSDYGQTNGLSTIGAMGPGNIGPPQIEELKVIPETSEENNEDIWNSEEIPEGAEYDDMWDVREIPEYEIIFRQQVGTEDIFLGLSKKDSSTGCCSELVAKIKLPNTNPSDIQIDIQETILDLRTPQKKLLITLPELVECTSAKAFYIPETETLEITMTMKRELDIANFF

Target ORF information:

RefSeq Version	NM_173494.2
Organism	Homo sapiens(human)
Definition	Homo sapiens dynein axonemal assembly factor 6 (DNAAF6), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_173494.2

ORF Insert Sequence:

ATGGAATCTG AAAATATGGA TTCTGAAAAT ATGAAGACAG AAAATATGGA ATCTCAAAAT 
GTAGACTTTG AGAGTGTTTC TTCAGTTACA GCTCTGGAAG CCCTCTCTAA GCTACTTAAT 
CCTGAAGAAG AGGATGATTC TGACTATGGA CAGACAAATG GTTTATCTAC TATTGGAGCC 
ATGGGTCCTG GGAATATTGG ACCACCCCAA ATAGAAGAGC TCAAAGTCAT CCCTGAAACC 
AGCGAGGAAA ATAATGAGGA CATCTGGAAT TCAGAAGAGA TTCCAGAAGG AGCAGAATAT 
GATGATATGT GGGATGTTAG AGAAATCCCA GAGTATGAGA TTATATTCAG ACAGCAGGTG 
GGAACTGAAG ATATATTTTT AGGGTTGTCA AAAAAGGACT CCTCAACAGG TTGTTGCAGT 
GAACTAGTGG CTAAAATTAA ATTGCCAAAT ACAAACCCTT CTGATATTCA AATTGATATC 
CAGGAAACAA TCCTTGACCT TCGTACTCCT CAGAAGAAGC TGTTGATAAC TCTTCCTGAG 
CTGGTGGAAT GTACCAGTGC CAAAGCATTC TATATCCCAG AGACTGAAAC TCTTGAAATC 
ACTATGACTA TGAAAAGAGA GTTAGATATT GCTAATTTCT TCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PIH1D3 ( NM_001169154.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001162625.1 Homo sapiens dynein axonemal assembly factor 6 (DNAAF6), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu22203
Clone ID Related Accession (Same CDS sequence)	XM_011530855.1 , NM_173494.2 , XM_011530855.2 , NM_001169154.1 , NM_173494.1
Accession Version	NM_001169154.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 645bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-19
Organism	Homo sapiens(human)
Product	protein PIH1D3
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BC033510.1, AL136112.10 and AI147427.1. On Aug 31, 2013 this sequence version replaced XM_005262075.1. Transcript Variant: This variant (1) represents the longer transcript. Both variants 1 and 2 encode the same protein. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. ##Evidence-Data-START## CDS exon combination :: BC033510.1, ERR279825.1372.1 [ECO:0000331] RNAseq introns :: single sample supports all introns SAMEA1968968, SAMEA2148874 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGAATCTG AAAATATGGA TTCTGAAAAT ATGAAGACAG AAAATATGGA ATCTCAAAAT 
GTAGACTTTG AGAGTGTTTC TTCAGTTACA GCTCTGGAAG CCCTCTCTAA GCTACTTAAT 
CCTGAAGAAG AGGATGATTC TGACTATGGA CAGACAAATG GTTTATCTAC TATTGGAGCC 
ATGGGTCCTG GGAATATTGG ACCACCCCAA ATAGAAGAGC TCAAAGTCAT CCCTGAAACC 
AGCGAGGAAA ATAATGAGGA CATCTGGAAT TCAGAAGAGA TTCCAGAAGG AGCAGAATAT 
GATGATATGT GGGATGTTAG AGAAATCCCA GAGTATGAGA TTATATTCAG ACAGCAGGTG 
GGAACTGAAG ATATATTTTT AGGGTTGTCA AAAAAGGACT CCTCAACAGG TTGTTGCAGT 
GAACTAGTGG CTAAAATTAA ATTGCCAAAT ACAAACCCTT CTGATATTCA AATTGATATC 
CAGGAAACAA TCCTTGACCT TCGTACTCCT CAGAAGAAGC TGTTGATAAC TCTTCCTGAG 
CTGGTGGAAT GTACCAGTGC CAAAGCATTC TATATCCCAG AGACTGAAAC TCTTGAAATC 
ACTATGACTA TGAAAAGAGA GTTAGATATT GCTAATTTCT TCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001162625.1
CDS	338..982
Translation	MESENMDSENMKTENMESQNVDFESVSSVTALEALSKLLNPEEEDDSDYGQTNGLSTIGAMGPGNIGPPQIEELKVIPETSEENNEDIWNSEEIPEGAEYDDMWDVREIPEYEIIFRQQVGTEDIFLGLSKKDSSTGCCSELVAKIKLPNTNPSDIQIDIQETILDLRTPQKKLLITLPELVECTSAKAFYIPETETLEITMTMKRELDIANFF

Target ORF information:

RefSeq Version	NM_001169154.1
Organism	Homo sapiens(human)
Definition	Homo sapiens dynein axonemal assembly factor 6 (DNAAF6), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001169154.1

ORF Insert Sequence:

ATGGAATCTG AAAATATGGA TTCTGAAAAT ATGAAGACAG AAAATATGGA ATCTCAAAAT 
GTAGACTTTG AGAGTGTTTC TTCAGTTACA GCTCTGGAAG CCCTCTCTAA GCTACTTAAT 
CCTGAAGAAG AGGATGATTC TGACTATGGA CAGACAAATG GTTTATCTAC TATTGGAGCC 
ATGGGTCCTG GGAATATTGG ACCACCCCAA ATAGAAGAGC TCAAAGTCAT CCCTGAAACC 
AGCGAGGAAA ATAATGAGGA CATCTGGAAT TCAGAAGAGA TTCCAGAAGG AGCAGAATAT 
GATGATATGT GGGATGTTAG AGAAATCCCA GAGTATGAGA TTATATTCAG ACAGCAGGTG 
GGAACTGAAG ATATATTTTT AGGGTTGTCA AAAAAGGACT CCTCAACAGG TTGTTGCAGT 
GAACTAGTGG CTAAAATTAA ATTGCCAAAT ACAAACCCTT CTGATATTCA AATTGATATC 
CAGGAAACAA TCCTTGACCT TCGTACTCCT CAGAAGAAGC TGTTGATAAC TCTTCCTGAG 
CTGGTGGAAT GTACCAGTGC CAAAGCATTC TATATCCCAG AGACTGAAAC TCTTGAAATC 
ACTATGACTA TGAAAAGAGA GTTAGATATT GCTAATTTCT TCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PIH1D3 ( NM_173494.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_775765.1 Homo sapiens PIH1 domain containing 3 (PIH1D3), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu22203
Clone ID Related Accession (Same CDS sequence)	XM_011530855.1 , NM_173494.2 , XM_011530855.2 , NM_001169154.1 , NM_173494.1
Accession Version	NM_173494.1	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 645bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2018-11-17
Organism	Homo sapiens(human)
Product	protein PIH1D3
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BC033510.1. This sequence is a reference standard in the RefSeqGene project. Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 1. Both variants 1 and 2 encode the same protein. ##Evidence-Data-START## Transcript exon combination :: BC033510.1, ERR279825.1372.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968968, SAMEA2144333 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGAATCTG AAAATATGGA TTCTGAAAAT ATGAAGACAG AAAATATGGA ATCTCAAAAT 
GTAGACTTTG AGAGTGTTTC TTCAGTTACA GCTCTGGAAG CCCTCTCTAA GCTACTTAAT 
CCTGAAGAAG AGGATGATTC TGACTATGGA CAGACAAATG GTTTATCTAC TATTGGAGCC 
ATGGGTCCTG GGAATATTGG ACCACCCCAA ATAGAAGAGC TCAAAGTCAT CCCTGAAACC 
AGCGAGGAAA ATAATGAGGA CATCTGGAAT TCAGAAGAGA TTCCAGAAGG AGCAGAATAT 
GATGATATGT GGGATGTTAG AGAAATCCCA GAGTATGAGA TTATATTCAG ACAGCAGGTG 
GGAACTGAAG ATATATTTTT AGGGTTGTCA AAAAAGGACT CCTCAACAGG TTGTTGCAGT 
GAACTAGTGG CTAAAATTAA ATTGCCAAAT ACAAACCCTT CTGATATTCA AATTGATATC 
CAGGAAACAA TCCTTGACCT TCGTACTCCT CAGAAGAAGC TGTTGATAAC TCTTCCTGAG 
CTGGTGGAAT GTACCAGTGC CAAAGCATTC TATATCCCAG AGACTGAAAC TCTTGAAATC 
ACTATGACTA TGAAAAGAGA GTTAGATATT GCTAATTTCT TCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_775765.1
CDS	63..707
Translation	MESENMDSENMKTENMESQNVDFESVSSVTALEALSKLLNPEEEDDSDYGQTNGLSTIGAMGPGNIGPPQIEELKVIPETSEENNEDIWNSEEIPEGAEYDDMWDVREIPEYEIIFRQQVGTEDIFLGLSKKDSSTGCCSELVAKIKLPNTNPSDIQIDIQETILDLRTPQKKLLITLPELVECTSAKAFYIPETETLEITMTMKRELDIANFF

Target ORF information:

RefSeq Version	NM_173494.1
Organism	Homo sapiens(human)
Definition	Homo sapiens PIH1 domain containing 3 (PIH1D3), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_173494.1

ORF Insert Sequence:

ATGGAATCTG AAAATATGGA TTCTGAAAAT ATGAAGACAG AAAATATGGA ATCTCAAAAT 
GTAGACTTTG AGAGTGTTTC TTCAGTTACA GCTCTGGAAG CCCTCTCTAA GCTACTTAAT 
CCTGAAGAAG AGGATGATTC TGACTATGGA CAGACAAATG GTTTATCTAC TATTGGAGCC 
ATGGGTCCTG GGAATATTGG ACCACCCCAA ATAGAAGAGC TCAAAGTCAT CCCTGAAACC 
AGCGAGGAAA ATAATGAGGA CATCTGGAAT TCAGAAGAGA TTCCAGAAGG AGCAGAATAT 
GATGATATGT GGGATGTTAG AGAAATCCCA GAGTATGAGA TTATATTCAG ACAGCAGGTG 
GGAACTGAAG ATATATTTTT AGGGTTGTCA AAAAAGGACT CCTCAACAGG TTGTTGCAGT 
GAACTAGTGG CTAAAATTAA ATTGCCAAAT ACAAACCCTT CTGATATTCA AATTGATATC 
CAGGAAACAA TCCTTGACCT TCGTACTCCT CAGAAGAAGC TGTTGATAAC TCTTCCTGAG 
CTGGTGGAAT GTACCAGTGC CAAAGCATTC TATATCCCAG AGACTGAAAC TCTTGAAATC 
ACTATGACTA TGAAAAGAGA GTTAGATATT GCTAATTTCT TCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PIH1D3 ( XM_011530855.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_011529157.1 Homo sapiens PIH1 domain containing 3 (PIH1D3), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OHu22203
Clone ID Related Accession (Same CDS sequence)	XM_011530855.1 , NM_173494.2 , XM_011530855.2 , NM_001169154.1 , NM_173494.1
Accession Version	XM_011530855.1	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 645bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2015-03-11
Organism	Homo sapiens(Human)
Product	protein PIH1D3 isoform X1
Comment

ATGGAATCTG AAAATATGGA TTCTGAAAAT ATGAAGACAG AAAATATGGA ATCTCAAAAT 
GTAGACTTTG AGAGTGTTTC TTCAGTTACA GCTCTGGAAG CCCTCTCTAA GCTACTTAAT 
CCTGAAGAAG AGGATGATTC TGACTATGGA CAGACAAATG GTTTATCTAC TATTGGAGCC 
ATGGGTCCTG GGAATATTGG ACCACCCCAA ATAGAAGAGC TCAAAGTCAT CCCTGAAACC 
AGCGAGGAAA ATAATGAGGA CATCTGGAAT TCAGAAGAGA TTCCAGAAGG AGCAGAATAT 
GATGATATGT GGGATGTTAG AGAAATCCCA GAGTATGAGA TTATATTCAG ACAGCAGGTG 
GGAACTGAAG ATATATTTTT AGGGTTGTCA AAAAAGGACT CCTCAACAGG TTGTTGCAGT 
GAACTAGTGG CTAAAATTAA ATTGCCAAAT ACAAACCCTT CTGATATTCA AATTGATATC 
CAGGAAACAA TCCTTGACCT TCGTACTCCT CAGAAGAAGC TGTTGATAAC TCTTCCTGAG 
CTGGTGGAAT GTACCAGTGC CAAAGCATTC TATATCCCAG AGACTGAAAC TCTTGAAATC 
ACTATGACTA TGAAAAGAGA GTTAGATATT GCTAATTTCT TCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_011529157.1
Translation	MESENMDSENMKTENMESQNVDFESVSSVTALEALSKLLNPEEEDDSDYGQTNGLSTIGAMGPGNIGPPQIEELKVIPETSEENNEDIWNSEEIPEGAEYDDMWDVREIPEYEIIFRQQVGTEDIFLGLSKKDSSTGCCSELVAKIKLPNTNPSDIQIDIQETILDLRTPQKKLLITLPELVECTSAKAFYIPETETLEITMTMKRELDIANFF

Target ORF information:

RefSeq Version	XM_011530855.1
Organism	Homo sapiens(Human)
Definition	Homo sapiens PIH1 domain containing 3 (PIH1D3), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011530855.1

ORF Insert Sequence:

ATGGAATCTG AAAATATGGA TTCTGAAAAT ATGAAGACAG AAAATATGGA ATCTCAAAAT 
GTAGACTTTG AGAGTGTTTC TTCAGTTACA GCTCTGGAAG CCCTCTCTAA GCTACTTAAT 
CCTGAAGAAG AGGATGATTC TGACTATGGA CAGACAAATG GTTTATCTAC TATTGGAGCC 
ATGGGTCCTG GGAATATTGG ACCACCCCAA ATAGAAGAGC TCAAAGTCAT CCCTGAAACC 
AGCGAGGAAA ATAATGAGGA CATCTGGAAT TCAGAAGAGA TTCCAGAAGG AGCAGAATAT 
GATGATATGT GGGATGTTAG AGAAATCCCA GAGTATGAGA TTATATTCAG ACAGCAGGTG 
GGAACTGAAG ATATATTTTT AGGGTTGTCA AAAAAGGACT CCTCAACAGG TTGTTGCAGT 
GAACTAGTGG CTAAAATTAA ATTGCCAAAT ACAAACCCTT CTGATATTCA AATTGATATC 
CAGGAAACAA TCCTTGACCT TCGTACTCCT CAGAAGAAGC TGTTGATAAC TCTTCCTGAG 
CTGGTGGAAT GTACCAGTGC CAAAGCATTC TATATCCCAG AGACTGAAAC TCTTGAAATC 
ACTATGACTA TGAAAAGAGA GTTAGATATT GCTAATTTCT TCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PIH1D3 ( XM_011530855.2 ) cDNA ORF clone, Homo sapiens(human) -> XP_011529157.1 Homo sapiens PIH1 domain containing 3 (PIH1D3), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OHu22203
Clone ID Related Accession (Same CDS sequence)	XM_011530855.1 , NM_173494.2 , XM_011530855.2 , NM_001169154.1 , NM_173494.1
Accession Version	XM_011530855.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 645bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	protein PIH1D3 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000023.11) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 6, 2016 this sequence version replaced XM_011530855.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGAATCTG AAAATATGGA TTCTGAAAAT ATGAAGACAG AAAATATGGA ATCTCAAAAT 
GTAGACTTTG AGAGTGTTTC TTCAGTTACA GCTCTGGAAG CCCTCTCTAA GCTACTTAAT 
CCTGAAGAAG AGGATGATTC TGACTATGGA CAGACAAATG GTTTATCTAC TATTGGAGCC 
ATGGGTCCTG GGAATATTGG ACCACCCCAA ATAGAAGAGC TCAAAGTCAT CCCTGAAACC 
AGCGAGGAAA ATAATGAGGA CATCTGGAAT TCAGAAGAGA TTCCAGAAGG AGCAGAATAT 
GATGATATGT GGGATGTTAG AGAAATCCCA GAGTATGAGA TTATATTCAG ACAGCAGGTG 
GGAACTGAAG ATATATTTTT AGGGTTGTCA AAAAAGGACT CCTCAACAGG TTGTTGCAGT 
GAACTAGTGG CTAAAATTAA ATTGCCAAAT ACAAACCCTT CTGATATTCA AATTGATATC 
CAGGAAACAA TCCTTGACCT TCGTACTCCT CAGAAGAAGC TGTTGATAAC TCTTCCTGAG 
CTGGTGGAAT GTACCAGTGC CAAAGCATTC TATATCCCAG AGACTGAAAC TCTTGAAATC 
ACTATGACTA TGAAAAGAGA GTTAGATATT GCTAATTTCT TCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_011529157.1
CDS	178..822
Translation	MESENMDSENMKTENMESQNVDFESVSSVTALEALSKLLNPEEEDDSDYGQTNGLSTIGAMGPGNIGPPQIEELKVIPETSEENNEDIWNSEEIPEGAEYDDMWDVREIPEYEIIFRQQVGTEDIFLGLSKKDSSTGCCSELVAKIKLPNTNPSDIQIDIQETILDLRTPQKKLLITLPELVECTSAKAFYIPETETLEITMTMKRELDIANFF

Target ORF information:

RefSeq Version	XM_011530855.2
Organism	Homo sapiens(human)
Definition	Homo sapiens PIH1 domain containing 3 (PIH1D3), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011530855.2

ORF Insert Sequence:

ATGGAATCTG AAAATATGGA TTCTGAAAAT ATGAAGACAG AAAATATGGA ATCTCAAAAT 
GTAGACTTTG AGAGTGTTTC TTCAGTTACA GCTCTGGAAG CCCTCTCTAA GCTACTTAAT 
CCTGAAGAAG AGGATGATTC TGACTATGGA CAGACAAATG GTTTATCTAC TATTGGAGCC 
ATGGGTCCTG GGAATATTGG ACCACCCCAA ATAGAAGAGC TCAAAGTCAT CCCTGAAACC 
AGCGAGGAAA ATAATGAGGA CATCTGGAAT TCAGAAGAGA TTCCAGAAGG AGCAGAATAT 
GATGATATGT GGGATGTTAG AGAAATCCCA GAGTATGAGA TTATATTCAG ACAGCAGGTG 
GGAACTGAAG ATATATTTTT AGGGTTGTCA AAAAAGGACT CCTCAACAGG TTGTTGCAGT 
GAACTAGTGG CTAAAATTAA ATTGCCAAAT ACAAACCCTT CTGATATTCA AATTGATATC 
CAGGAAACAA TCCTTGACCT TCGTACTCCT CAGAAGAAGC TGTTGATAAC TCTTCCTGAG 
CTGGTGGAAT GTACCAGTGC CAAAGCATTC TATATCCCAG AGACTGAAAC TCTTGAAATC 
ACTATGACTA TGAAAAGAGA GTTAGATATT GCTAATTTCT TCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

X-linked primary ciliary dyskinesia due to mutations in the cytoplasmic axonemal dynein assembly factor PIH1D3.
Nature communications814279(2017 Feb)
Olcese C,Patel MP,Shoemark A,Kiviluoto S,Legendre M,Williams HJ,Vaughan CK,Hayward J,Goldenberg A,Emes RD,Munye MM,Dyer L,Cahill T,Bevillard J,Gehrig C,Guipponi M,Chantot S,Duquesnoy P,Thomas L,Jeanson L,Copin B,Tamalet A,Thauvin-Robinet C,Papon JF,Garin A,Pin I,Vera G,Aurora P,Fassad MR,Jenkins L,Boustred C,Cullup T,Dixon M,Onoufriadis A,Bush A,Chung EM,Antonarakis SE,Loebinger MR,Wilson R,Armengot M,Escudier E,Hogg C,,Amselem S,Sun Z,Bartoloni L,Blouin JL,Mitchison HM

Mutations in PIH1D3 Cause X-Linked Primary Ciliary Dyskinesia with Outer and Inner Dynein Arm Defects.
American journal of human genetics100(1)160-168(2017 Jan)
Paff T,Loges NT,Aprea I,Wu K,Bakey Z,Haarman EG,Daniels JMA,Sistermans EA,Bogunovic N,Dougherty GW,H?ben IM,Gro?e-Onnebrink J,Matter A,Olbrich H,Werner C,Pals G,Schmidts M,Omran H,Micha D

Pih1d3 is required for cytoplasmic preassembly of axonemal dynein in mouse sperm.
The Journal of cell biology204(2)203-13(2014 Jan)
Dong F,Shinohara K,Botilde Y,Nabeshima R,Asai Y,Fukumoto A,Hasegawa T,Matsuo M,Takeda H,Shiratori H,Nakamura T,Hamada H

Immunomic analysis of human sarcoma.
Proceedings of the National Academy of Sciences of the United States of America100(5)2651-6(2003 Mar)
Lee SY,Obata Y,Yoshida M,Stockert E,Williamson B,Jungbluth AA,Chen YT,Old LJ,Scanlan MJ

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PIH1D3 cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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