CPA2 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	CPA2
Entrez Gene ID	1358
Full Name	carboxypeptidase A2
General protein information	Preferred Names carboxypeptidase A2 Names carboxypeptidase A2 carboxypeptidase A2 (pancreatic)
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 7 Map Location: 7q32.2
Summary	Three different forms of human pancreatic procarboxypeptidase A have been isolated. The encoded protein represents the A2 form, which is a monomeric protein with different biochemical properties from the A1 and A3 forms. The A2 form of pancreatic procarboxypeptidase acts on aromatic C-terminal residues and is a secreted protein. [provided by RefSeq, Dec 2008].
Disorder MIM:	600688

mRNA and Protein(s)

mRNA	Protein	Name
NM_001869.3	NP_001860.2	carboxypeptidase A2 precursor
NM_001869.2	NP_001860.2	carboxypeptidase A2 precursor

Pathways from BioSystems

Homologies

Rattus norvegicus (Norway rat)	Cpa2	NP_001013101.2
Gallus gallus (chicken)	CPA2	NP_001244143.1
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP011435	XP_317868.4
Pan troglodytes (chimpanzee)	CPA2	XP_001156440.2
Danio rerio (zebrafish)	cpa2	NP_001003446.1
Drosophila melanogaster (fruit fly)	CG18585	NP_609132.1
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP011434	XP_554784.3
Caenorhabditis elegans (roundworm)	ZC434.9	NP_001251358.1
Caenorhabditis elegans (roundworm)	suro-1	NP_492177.2
	CPA2	XP_001095065.2
Drosophila melanogaster (fruit fly)	CG7025	NP_609133.2
Caenorhabditis elegans (roundworm)	T06A4.1	NP_871809.1
Caenorhabditis elegans (roundworm)	CELE_Y47G6A.19	NP_001021763.1
Caenorhabditis elegans (roundworm)	T06A4.3	NP_001021611.1
Magnaporthe oryzae (rice blast fungus)	MGG_17822	XP_003720328.1
Homo sapiens (human)	CPA2	NP_001860.2
Canis lupus familiaris (dog)	CPA2	XP_532425.2
Mus musculus (house mouse)	Cpa2	NP_001019869.1
Danio rerio (zebrafish)	cpa4	NP_001002217.1
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP008370	XP_001689001.1
Caenorhabditis elegans (roundworm)	Y18H1A.9	NP_490776.2
Caenorhabditis elegans (roundworm)	CELE_W01A8.6	NP_492003.2

Gene Ontology
Bibliography

Related articles in PubMed

Complex Formation of Human Proelastases with Procarboxypeptidases A1 and A2.
Szab? A, Pilsak C, Bence M, Witt H, Sahin-T?th M
The Journal of biological chemistry291(34)17706-16(2016 08)

Widespread Expansion of Protein Interaction Capabilities by Alternative Splicing.
Yang X, Coulombe-Huntington J, Kang S, Sheynkman GM, Hao T, Richardson A, Sun S, Yang F, Shen YA, Murray RR, Spirohn K, Begg BE, Duran-Frigola M, MacWilliams A, Pevzner SJ, Zhong Q, Trigg SA, Tam S, Ghamsari L, Sahni N, Yi S, Rodriguez MD, Balcha D, Tan G, Costanzo M, Andrews B, Boone C, Zhou XJ, Salehi-Ashtiani K, Charloteaux B, Chen AA, Calderwood MA, Aloy P, Roth FP, Hill DE, Iakoucheva LM, Xia Y, Vidal M
Cell164(4)805-17(2016 Feb)

Variants in pancreatic carboxypeptidase genes CPA2 and CPB1 are not associated with chronic pancreatitis.
Nakano E, Geisz A, Masamune A, Niihori T, Hamada S, Kume K, Kakuta Y, Aoki Y, Matsubara Y, Ebert K, Ludwig M, Braun M, Groneberg DA, Shimosegawa T, Sahin-T?th M, Witt H
American journal of physiology. Gastrointestinal and liver physiology309(8)G688-94(2015 Oct)

Probing the Residual Structure of the Low Populated Denatured State of ADA2h under Folding Conditions by Relaxation Dispersion Nuclear Magnetic Resonance Spectroscopy.
Pustovalova Y, Kukic P, Vendruscolo M, Korzhnev DM
Biochemistry54(30)4611-22(2015 Aug)

Chymotrypsin C is a co-activator of human pancreatic procarboxypeptidases A1 and A2.
Szmola R, Bence M, Carpentieri A, Szab? A, Costello CE, Samuelson J, Sahin-T?th M
The Journal of biological chemistry286(3)1819-27(2011 Jan)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Complex Formation of Human Proelastases with Procarboxypeptidases A1 and A2.
Title: Complex Formation of Human Proelastases with Procarboxypeptidases A1 and A2.

This study showed that CPA2 and CPB1 variants are not associated with chronic pancreatitis.
Title: Variants in pancreatic carboxypeptidase genes CPA2 and CPB1 are not associated with chronic pancreatitis.

CPMG RD data analysis thus allowed a detailed structural characterization of the ADA2h denatured state under folding conditions not previously achieved for this protein.
Title: Probing the Residual Structure of the Low Populated Denatured State of ADA2h under Folding Conditions by Relaxation Dispersion Nuclear Magnetic Resonance Spectroscopy.

Chymotrypsin C is a co-activator of human pancreatic procarboxypeptidases A1 and A2.
Title: Chymotrypsin C is a co-activator of human pancreatic procarboxypeptidases A1 and A2.

Clinical trial of gene-disease association and gene-environment interaction. (HuGE Navigator)
Title: Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.

The following CPA2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the CPA2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu03721	NM_001869.3 Latest version!	Homo sapiens carboxypeptidase A2 (CPA2), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$159.50-$223.30 $319.00
View Old Accession Versions >>
OHu03721	NM_001869.2	Homo sapiens carboxypeptidase A2 (CPA2), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$265.30 $379.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

CPA2 ( NM_001869.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_001860.2 Homo sapiens carboxypeptidase A2 (CPA2), mRNA.

Price & Availability↑

CloneID	OHu03721
Clone ID Related Accession (Same CDS sequence)	NM_001869.3 , NM_001869.2
Accession Version	NM_001869.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1260bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-09-24
Organism	Homo sapiens(human)
Product	carboxypeptidase A2 precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BC007009.1, CD613167.1 and BX106544.1. On Nov 22, 2018 this sequence version replaced NM_001869.2. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC007009.1, BC014571.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968832, SAMEA1968968 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000222481.9/ ENSP00000222481.4 RefSeq Select criteria :: based on single protein-coding transcript ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGGCCATGA GGTTGATCCT GTTTTTTGGT GCCCTTTTTG GGCATATCTA CTGTCTAGAA 
ACATTTGTGG GAGACCAAGT TCTTGAGATT GTACCAAGCA ATGAAGAACA AATTAAAAAT 
CTGCTACAAT TGGAGGCTCA AGAACATCTC CAGCTTGATT TTTGGAAATC ACCCACCACC 
CCAGGGGAGA CAGCCCACGT CCGAGTTCCC TTCGTCAACG TCCAGGCAGT CAAAGTGTTC 
TTGGAGTCCC AGGGAATTGC CTATTCCATC ATGATTGAAG ACGTGCAGGT CCTGTTGGAC 
AAAGAGAATG AAGAAATGCT TTTTAATAGG AGAAGAGAAC GGAGTGGTAA CTTCAATTTT 
GGGGCCTACC ATACCCTGGA AGAGATTTCC CAAGAAATGG ATAACCTCGT GGCTGAGCAC 
CCTGGTCTAG TGAGCAAAGT GAATATTGGC TCTTCTTTTG AGAACCGGCC TATGAACGTG 
CTCAAGTTCA GCACCGGAGG AGACAAGCCA GCTATCTGGC TGGATGCTGG GATCCATGCT 
CGAGAGTGGG TTACACAAGC TACGGCACTT TGGACAGCAA ATAAGATTGT TTCTGATTAT 
GGAAAGGACC CATCCATCAC TTCCATTCTG GATGCCCTGG ATATCTTCCT CCTGCCAGTC 
ACAAACCCTG ATGGATACGT GTTCTCTCAA ACCAAAAATC GTATGTGGCG GAAGACCCGG 
TCCAAGGTAT CTGGAAGCCT CTGTGTTGGT GTGGATCCTA ACCGGAACTG GGATGCAGGT 
TTTGGAGGAC CTGGAGCCAG CAGCAACCCT TGCTCTGATT CATACCACGG ACCCAGTGCC 
AACTCTGAAG TTGAAGTGAA ATCCATAGTG GACTTCATCA AGAGTCATGG AAAAGTCAAG 
GCCTTCATTA CCCTCCACAG CTATTCCCAG CTGCTGATGT TCCCCTATGG GTACAAATGT 
ACCAAGTTAG ATGACTTTGA TGAGCTGAGT GAAGTGGCCC AAAAGGCTGC CCAATCTCTG 
AGAAGCCTGC ATGGCACCAA GTACAAAGTG GGACCAATCT GCTCTGTCAT CTACCAAGCC 
AGTGGAGGAA GCATTGACTG GTCCTATGAT TATGGCATCA AGTACTCATT TGCCTTTGAA 
CTGAGAGACA CAGGGCGCTA CGGCTTCCTC TTGCCAGCCC GTCAGATCCT GCCCACAGCC 
GAGGAGACCT GGCTTGGCTT GAAGGCAATC ATGGAGCATG TGCGAGACCA CCCCTATTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001860.2
CDS	20..1279
Translation	MAMRLILFFGALFGHIYCLETFVGDQVLEIVPSNEEQIKNLLQLEAQEHLQLDFWKSPTTPGETAHVRVPFVNVQAVKVFLESQGIAYSIMIEDVQVLLDKENEEMLFNRRRERSGNFNFGAYHTLEEISQEMDNLVAEHPGLVSKVNIGSSFENRPMNVLKFSTGGDKPAIWLDAGIHAREWVTQATALWTANKIVSDYGKDPSITSILDALDIFLLPVTNPDGYVFSQTKNRMWRKTRSKVSGSLCVGVDPNRNWDAGFGGPGASSNPCSDSYHGPSANSEVEVKSIVDFIKSHGKVKAFITLHSYSQLLMFPYGYKCTKLDDFDELSEVAQKAAQSLRSLHGTKYKVGPICSVIYQASGGSIDWSYDYGIKYSFAFELRDTGRYGFLLPARQILPTAEETWLGLKAIMEHVRDHPY

Target ORF information:

RefSeq Version	NM_001869.3
Organism	Homo sapiens(human)
Definition	Homo sapiens carboxypeptidase A2 (CPA2), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001869.3

ORF Insert Sequence:

ATGGCCATGA GGTTGATCCT GTTTTTTGGT GCCCTTTTTG GGCATATCTA CTGTCTAGAA 
ACATTTGTGG GAGACCAAGT TCTTGAGATT GTACCAAGCA ATGAAGAACA AATTAAAAAT 
CTGCTACAAT TGGAGGCTCA AGAACATCTC CAGCTTGATT TTTGGAAATC ACCCACCACC 
CCAGGGGAGA CAGCCCACGT CCGAGTTCCC TTCGTCAACG TCCAGGCAGT CAAAGTGTTC 
TTGGAGTCCC AGGGAATTGC CTATTCCATC ATGATTGAAG ACGTGCAGGT CCTGTTGGAC 
AAAGAGAATG AAGAAATGCT TTTTAATAGG AGAAGAGAAC GGAGTGGTAA CTTCAATTTT 
GGGGCCTACC ATACCCTGGA AGAGATTTCC CAAGAAATGG ATAACCTCGT GGCTGAGCAC 
CCTGGTCTAG TGAGCAAAGT GAATATTGGC TCTTCTTTTG AGAACCGGCC TATGAACGTG 
CTCAAGTTCA GCACCGGAGG AGACAAGCCA GCTATCTGGC TGGATGCTGG GATCCATGCT 
CGAGAGTGGG TTACACAAGC TACGGCACTT TGGACAGCAA ATAAGATTGT TTCTGATTAT 
GGAAAGGACC CATCCATCAC TTCCATTCTG GATGCCCTGG ATATCTTCCT CCTGCCAGTC 
ACAAACCCTG ATGGATACGT GTTCTCTCAA ACCAAAAATC GTATGTGGCG GAAGACCCGG 
TCCAAGGTAT CTGGAAGCCT CTGTGTTGGT GTGGATCCTA ACCGGAACTG GGATGCAGGT 
TTTGGAGGAC CTGGAGCCAG CAGCAACCCT TGCTCTGATT CATACCACGG ACCCAGTGCC 
AACTCTGAAG TTGAAGTGAA ATCCATAGTG GACTTCATCA AGAGTCATGG AAAAGTCAAG 
GCCTTCATTA CCCTCCACAG CTATTCCCAG CTGCTGATGT TCCCCTATGG GTACAAATGT 
ACCAAGTTAG ATGACTTTGA TGAGCTGAGT GAAGTGGCCC AAAAGGCTGC CCAATCTCTG 
AGAAGCCTGC ATGGCACCAA GTACAAAGTG GGACCAATCT GCTCTGTCAT CTACCAAGCC 
AGTGGAGGAA GCATTGACTG GTCCTATGAT TATGGCATCA AGTACTCATT TGCCTTTGAA 
CTGAGAGACA CAGGGCGCTA CGGCTTCCTC TTGCCAGCCC GTCAGATCCT GCCCACAGCC 
GAGGAGACCT GGCTTGGCTT GAAGGCAATC ATGGAGCATG TGCGAGACCA CCCCTATTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

CPA2 ( NM_001869.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_001860.2 Homo sapiens carboxypeptidase A2 (CPA2), mRNA.

Price & Availability↑

CloneID	OHu03721
Clone ID Related Accession (Same CDS sequence)	NM_001869.3 , NM_001869.2
Accession Version	NM_001869.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1260bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-10-01
Organism	Homo sapiens(human)
Product	carboxypeptidase A2 precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BC007009.1, CD613167.1 and BX106544.1. On Dec 13, 2008 this sequence version replaced NM_001869.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC007009.1, BC014571.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968832, SAMEA1968968 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGCCATGA GGTTGATCCT GTTTTTTGGT GCCCTTTTTG GGCATATCTA CTGTCTAGAA 
ACATTTGTGG GAGACCAAGT TCTTGAGATT GTACCAAGCA ATGAAGAACA AATTAAAAAT 
CTGCTACAAT TGGAGGCTCA AGAACATCTC CAGCTTGATT TTTGGAAATC ACCCACCACC 
CCAGGGGAGA CAGCCCACGT CCGAGTTCCC TTCGTCAACG TCCAGGCAGT CAAAGTGTTC 
TTGGAGTCCC AGGGAATTGC CTATTCCATC ATGATTGAAG ACGTGCAGGT CCTGTTGGAC 
AAAGAGAATG AAGAAATGCT TTTTAATAGG AGAAGAGAAC GGAGTGGTAA CTTCAATTTT 
GGGGCCTACC ATACCCTGGA AGAGATTTCC CAAGAAATGG ATAACCTCGT GGCTGAGCAC 
CCTGGTCTAG TGAGCAAAGT GAATATTGGC TCTTCTTTTG AGAACCGGCC TATGAACGTG 
CTCAAGTTCA GCACCGGAGG AGACAAGCCA GCTATCTGGC TGGATGCTGG GATCCATGCT 
CGAGAGTGGG TTACACAAGC TACGGCACTT TGGACAGCAA ATAAGATTGT TTCTGATTAT 
GGAAAGGACC CATCCATCAC TTCCATTCTG GATGCCCTGG ATATCTTCCT CCTGCCAGTC 
ACAAACCCTG ATGGATACGT GTTCTCTCAA ACCAAAAATC GTATGTGGCG GAAGACCCGG 
TCCAAGGTAT CTGGAAGCCT CTGTGTTGGT GTGGATCCTA ACCGGAACTG GGATGCAGGT 
TTTGGAGGAC CTGGAGCCAG CAGCAACCCT TGCTCTGATT CATACCACGG ACCCAGTGCC 
AACTCTGAAG TTGAAGTGAA ATCCATAGTG GACTTCATCA AGAGTCATGG AAAAGTCAAG 
GCCTTCATTA CCCTCCACAG CTATTCCCAG CTGCTGATGT TCCCCTATGG GTACAAATGT 
ACCAAGTTAG ATGACTTTGA TGAGCTGAGT GAAGTGGCCC AAAAGGCTGC CCAATCTCTG 
AGAAGCCTGC ATGGCACCAA GTACAAAGTG GGACCAATCT GCTCTGTCAT CTACCAAGCC 
AGTGGAGGAA GCATTGACTG GTCCTATGAT TATGGCATCA AGTACTCATT TGCCTTTGAA 
CTGAGAGACA CAGGGCGCTA CGGCTTCCTC TTGCCAGCCC GTCAGATCCT GCCCACAGCC 
GAGGAGACCT GGCTTGGCTT GAAGGCAATC ATGGAGCATG TGCGAGACCA CCCCTATTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001860.2
CDS	20..1279
Translation	MAMRLILFFGALFGHIYCLETFVGDQVLEIVPSNEEQIKNLLQLEAQEHLQLDFWKSPTTPGETAHVRVPFVNVQAVKVFLESQGIAYSIMIEDVQVLLDKENEEMLFNRRRERSGNFNFGAYHTLEEISQEMDNLVAEHPGLVSKVNIGSSFENRPMNVLKFSTGGDKPAIWLDAGIHAREWVTQATALWTANKIVSDYGKDPSITSILDALDIFLLPVTNPDGYVFSQTKNRMWRKTRSKVSGSLCVGVDPNRNWDAGFGGPGASSNPCSDSYHGPSANSEVEVKSIVDFIKSHGKVKAFITLHSYSQLLMFPYGYKCTKLDDFDELSEVAQKAAQSLRSLHGTKYKVGPICSVIYQASGGSIDWSYDYGIKYSFAFELRDTGRYGFLLPARQILPTAEETWLGLKAIMEHVRDHPY

Target ORF information:

RefSeq Version	NM_001869.2
Organism	Homo sapiens(human)
Definition	Homo sapiens carboxypeptidase A2 (CPA2), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001869.2

ORF Insert Sequence:

ATGGCCATGA GGTTGATCCT GTTTTTTGGT GCCCTTTTTG GGCATATCTA CTGTCTAGAA 
ACATTTGTGG GAGACCAAGT TCTTGAGATT GTACCAAGCA ATGAAGAACA AATTAAAAAT 
CTGCTACAAT TGGAGGCTCA AGAACATCTC CAGCTTGATT TTTGGAAATC ACCCACCACC 
CCAGGGGAGA CAGCCCACGT CCGAGTTCCC TTCGTCAACG TCCAGGCAGT CAAAGTGTTC 
TTGGAGTCCC AGGGAATTGC CTATTCCATC ATGATTGAAG ACGTGCAGGT CCTGTTGGAC 
AAAGAGAATG AAGAAATGCT TTTTAATAGG AGAAGAGAAC GGAGTGGTAA CTTCAATTTT 
GGGGCCTACC ATACCCTGGA AGAGATTTCC CAAGAAATGG ATAACCTCGT GGCTGAGCAC 
CCTGGTCTAG TGAGCAAAGT GAATATTGGC TCTTCTTTTG AGAACCGGCC TATGAACGTG 
CTCAAGTTCA GCACCGGAGG AGACAAGCCA GCTATCTGGC TGGATGCTGG GATCCATGCT 
CGAGAGTGGG TTACACAAGC TACGGCACTT TGGACAGCAA ATAAGATTGT TTCTGATTAT 
GGAAAGGACC CATCCATCAC TTCCATTCTG GATGCCCTGG ATATCTTCCT CCTGCCAGTC 
ACAAACCCTG ATGGATACGT GTTCTCTCAA ACCAAAAATC GTATGTGGCG GAAGACCCGG 
TCCAAGGTAT CTGGAAGCCT CTGTGTTGGT GTGGATCCTA ACCGGAACTG GGATGCAGGT 
TTTGGAGGAC CTGGAGCCAG CAGCAACCCT TGCTCTGATT CATACCACGG ACCCAGTGCC 
AACTCTGAAG TTGAAGTGAA ATCCATAGTG GACTTCATCA AGAGTCATGG AAAAGTCAAG 
GCCTTCATTA CCCTCCACAG CTATTCCCAG CTGCTGATGT TCCCCTATGG GTACAAATGT 
ACCAAGTTAG ATGACTTTGA TGAGCTGAGT GAAGTGGCCC AAAAGGCTGC CCAATCTCTG 
AGAAGCCTGC ATGGCACCAA GTACAAAGTG GGACCAATCT GCTCTGTCAT CTACCAAGCC 
AGTGGAGGAA GCATTGACTG GTCCTATGAT TATGGCATCA AGTACTCATT TGCCTTTGAA 
CTGAGAGACA CAGGGCGCTA CGGCTTCCTC TTGCCAGCCC GTCAGATCCT GCCCACAGCC 
GAGGAGACCT GGCTTGGCTT GAAGGCAATC ATGGAGCATG TGCGAGACCA CCCCTATTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Complex Formation of Human Proelastases with Procarboxypeptidases A1 and A2.
The Journal of biological chemistry291(34)17706-16(2016 08)
Szab? A,Pilsak C,Bence M,Witt H,Sahin-T?th M

Widespread Expansion of Protein Interaction Capabilities by Alternative Splicing.
Cell164(4)805-17(2016 Feb)
Yang X,Coulombe-Huntington J,Kang S,Sheynkman GM,Hao T,Richardson A,Sun S,Yang F,Shen YA,Murray RR,Spirohn K,Begg BE,Duran-Frigola M,MacWilliams A,Pevzner SJ,Zhong Q,Trigg SA,Tam S,Ghamsari L,Sahni N,Yi S,Rodriguez MD,Balcha D,Tan G,Costanzo M,Andrews B,Boone C,Zhou XJ,Salehi-Ashtiani K,Charloteaux B,Chen AA,Calderwood MA,Aloy P,Roth FP,Hill DE,Iakoucheva LM,Xia Y,Vidal M

Variants in pancreatic carboxypeptidase genes CPA2 and CPB1 are not associated with chronic pancreatitis.
American journal of physiology. Gastrointestinal and liver physiology309(8)G688-94(2015 Oct)
Nakano E,Geisz A,Masamune A,Niihori T,Hamada S,Kume K,Kakuta Y,Aoki Y,Matsubara Y,Ebert K,Ludwig M,Braun M,Groneberg DA,Shimosegawa T,Sahin-T?th M,Witt H

Probing the Residual Structure of the Low Populated Denatured State of ADA2h under Folding Conditions by Relaxation Dispersion Nuclear Magnetic Resonance Spectroscopy.
Biochemistry54(30)4611-22(2015 Aug)
Pustovalova Y,Kukic P,Vendruscolo M,Korzhnev DM

Chymotrypsin C is a co-activator of human pancreatic procarboxypeptidases A1 and A2.
The Journal of biological chemistry286(3)1819-27(2011 Jan)
Szmola R,Bence M,Carpentieri A,Szab? A,Costello CE,Samuelson J,Sahin-T?th M

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CPA2 cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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