OCIAD2 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	OCIAD2
Entrez Gene ID	132299
Full Name	OCIA domain containing 2
General protein information	Preferred Names OCIA domain containing 2 Names OCIA domain-containing protein 2 ovarian carcinoma immunoreactive antigen-like protein
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 4 Map Location: 4p11

mRNA and Protein(s)

mRNA	Protein	Name
NM_001286773.1	NP_001273702.1	OCIA domain-containing protein 2 isoform 2
NM_152398.3	NP_689611.1	OCIA domain-containing protein 2 isoform 2
NM_001014446.2	NP_001014446.1	OCIA domain-containing protein 2 isoform 1
NM_001286774.1	NP_001273703.1	OCIA domain-containing protein 2 isoform 3
NM_001014446.3	NP_001014446.1	OCIA domain-containing protein 2 isoform 1

Pathways from BioSystems

Homologies

Xenopus tropicalis (tropical clawed frog)	ociad2	NP_001037952.1
Danio rerio (zebrafish)	ociad2	NP_001038321.1
	OCIAD2	XP_001104131.1
Bos taurus (cattle)	OCIAD2	NP_001029430.1
Canis lupus familiaris (dog)	OCIAD2	XP_003431872.1
Homo sapiens (human)	OCIAD2	NP_001014446.1
Pan troglodytes (chimpanzee)	OCIAD2	XP_003310442.1
Mus musculus (house mouse)	Ociad2	NP_081226.1
Rattus norvegicus (Norway rat)	Ociad2	NP_001258110.1

Gene Ontology
Bibliography

Related articles in PubMed

OCIAD2 suppressed tumor growth and invasion via AKT pathway in Hepatocelluar carcinoma.
Wu D, Yang X, Peng H, Guo D, Zhao W, Zhao C, Zhou X
Carcinogenesis38(9)910-919(2017 Sep)

OCIAD2 activates ?-secretase to enhance amyloid ? production by interacting with nicastrin.
Han J, Jung S, Jang J, Kam TI, Choi H, Kim BJ, Nah J, Jo DG, Nakagawa T, Nishimura M, Jung YK
Cellular and molecular life sciences : CMLS71(13)2561-76(2014 Jul)

Pathway bridge based multiobjective optimization approach for lurking pathway prediction.
Zhang R, Zhao C, Xiong Z, Zhou X
BioMed research international2014351095(2014)

Increased expression of OCIA domain containing 2 during stepwise progression of ovarian mucinous tumor.
Nagata C, Kobayashi H, Sakata A, Satomi K, Minami Y, Morishita Y, Ohara R, Yoshikawa H, Arai Y, Nishida M, Noguchi M
Pathology international62(7)471-6(2012 Jul)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

these data indicate that reduced expression of OCIAD2 by DNA hypermethylation plays an important role in hepatocellular carcinoma tumor growth and invasion.
Title: OCIAD2 suppressed tumor growth and invasion via AKT pathway in Hepatocelluar carcinoma.

OCIAD2 also increased the interaction of nicastrin with C99 and stimulated APP processing via gamma-secretase activation, but did not affect Notch processing
Title: OCIAD2 activates ?-secretase to enhance amyloid ? production by interacting with nicastrin.

it well explained the mechanism of TGFbeta induced OCIAD2 expression in cancer microenvironment, therefore providing an important clue for the future functional analysis of OCIAD2 in tumor pathogenesis.
Title: Pathway bridge based multiobjective optimization approach for lurking pathway prediction.

Like OCIAD1, OCIAD2 is a cancer-related protein and its expression level increases during the course of malignant progression and is thought to be a very useful marker for evaluating the malignancy of ovarian mucinous tumors.
Title: Increased expression of OCIA domain containing 2 during stepwise progression of ovarian mucinous tumor.

The following OCIAD2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the OCIAD2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu04151	NM_001014446.3 Latest version!	Homo sapiens OCIA domain containing 2 (OCIAD2), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
OHu05711	NM_152398.3 Latest version!	Homo sapiens OCIA domain containing 2 (OCIAD2), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
OHu05711	NM_001286773.1 Latest version!	Homo sapiens OCIA domain containing 2 (OCIAD2), transcript variant 3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
OHu05712	NM_001286774.1 Latest version!	Homo sapiens OCIA domain containing 2 (OCIAD2), transcript variant 4, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$69.30 $99.00
View Old Accession Versions >>
OHu04151	NM_001014446.2	Homo sapiens OCIA domain containing 2 (OCIAD2), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

OCIAD2 ( NM_001014446.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_001014446.1 Homo sapiens OCIA domain containing 2 (OCIAD2), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu04151
Clone ID Related Accession (Same CDS sequence)	NM_001014446.2 , NM_001014446.3
Accession Version	NM_001014446.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 465bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-02-23
Organism	Homo sapiens(human)
Product	OCIA domain-containing protein 2 isoform 1
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BI546814.1 and AK298305.1. On Nov 15, 2013 this sequence version replaced NM_001014446.1. Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (1). ##Evidence-Data-START## Transcript exon combination :: BG748993.1, AK298305.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGCTTCAG CGTCTGCTCG TGGAAACCAA GATAAAGATG CCCATTTTCC ACCACCAAGC 
AAGCAGAGCC TGTTGTTTTG TCCAAAATCA AAACTGCACA TCCACAGAGC AGAGATCTCA 
AAGATTATGC GAGAATGTCA GGAAGAAAGT TTCTGGAAGA GAGCTCTGCC TTTTTCTCTT 
GTAAGCATGC TTGTCACCCA GGGACTAGTC TACCAAGGTT ATTTGGCAGC TAATTCTAGA 
TTTGGATCAT TGCCCAAAGT TGCACTTGCT GGTCTCTTGG GATTTGGCCT TGGAAAGGTA 
TCATACATAG GAGTATGCCA GAGTAAATTC CATTTTTTTG AAGATCAGCT CCGTGGGGCT 
GGTTTTGGTC CACAGCATAA CAGGCACTGC CTCCTTACCT GTGAGGAATG CAAAATAAAG 
CATGGATTAA GTGAGAAGGG AGACTCTCAG CCTTCAGCTT CCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001014446.1
CDS	234..698
Translation	MASASARGNQDKDAHFPPPSKQSLLFCPKSKLHIHRAEISKIMRECQEESFWKRALPFSLVSMLVTQGLVYQGYLAANSRFGSLPKVALAGLLGFGLGKVSYIGVCQSKFHFFEDQLRGAGFGPQHNRHCLLTCEECKIKHGLSEKGDSQPSAS

Target ORF information:

RefSeq Version	NM_001014446.2
Organism	Homo sapiens(human)
Definition	Homo sapiens OCIA domain containing 2 (OCIAD2), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001014446.2

ORF Insert Sequence:

ATGGCTTCAG CGTCTGCTCG TGGAAACCAA GATAAAGATG CCCATTTTCC ACCACCAAGC 
AAGCAGAGCC TGTTGTTTTG TCCAAAATCA AAACTGCACA TCCACAGAGC AGAGATCTCA 
AAGATTATGC GAGAATGTCA GGAAGAAAGT TTCTGGAAGA GAGCTCTGCC TTTTTCTCTT 
GTAAGCATGC TTGTCACCCA GGGACTAGTC TACCAAGGTT ATTTGGCAGC TAATTCTAGA 
TTTGGATCAT TGCCCAAAGT TGCACTTGCT GGTCTCTTGG GATTTGGCCT TGGAAAGGTA 
TCATACATAG GAGTATGCCA GAGTAAATTC CATTTTTTTG AAGATCAGCT CCGTGGGGCT 
GGTTTTGGTC CACAGCATAA CAGGCACTGC CTCCTTACCT GTGAGGAATG CAAAATAAAG 
CATGGATTAA GTGAGAAGGG AGACTCTCAG CCTTCAGCTT CCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

OCIAD2 ( NM_001014446.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_001014446.1 Homo sapiens OCIA domain containing 2 (OCIAD2), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu04151
Clone ID Related Accession (Same CDS sequence)	NM_001014446.2 , NM_001014446.3
Accession Version	NM_001014446.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 465bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-10-25
Organism	Homo sapiens(human)
Product	OCIA domain-containing protein 2 isoform 1
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AK298305.1 and AC105444.2. On May 17, 2019 this sequence version replaced NM_001014446.2. Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (1). ##Evidence-Data-START## Transcript exon combination :: AK298305.1, AW248322.1 [ECO:0000332] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000508632.6/ ENSP00000423014.1 RefSeq Select criteria :: based on conservation, expression, longest protein ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGGCTTCAG CGTCTGCTCG TGGAAACCAA GATAAAGATG CCCATTTTCC ACCACCAAGC 
AAGCAGAGCC TGTTGTTTTG TCCAAAATCA AAACTGCACA TCCACAGAGC AGAGATCTCA 
AAGATTATGC GAGAATGTCA GGAAGAAAGT TTCTGGAAGA GAGCTCTGCC TTTTTCTCTT 
GTAAGCATGC TTGTCACCCA GGGACTAGTC TACCAAGGTT ATTTGGCAGC TAATTCTAGA 
TTTGGATCAT TGCCCAAAGT TGCACTTGCT GGTCTCTTGG GATTTGGCCT TGGAAAGGTA 
TCATACATAG GAGTATGCCA GAGTAAATTC CATTTTTTTG AAGATCAGCT CCGTGGGGCT 
GGTTTTGGTC CACAGCATAA CAGGCACTGC CTCCTTACCT GTGAGGAATG CAAAATAAAG 
CATGGATTAA GTGAGAAGGG AGACTCTCAG CCTTCAGCTT CCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001014446.1
CDS	180..644
Translation	MASASARGNQDKDAHFPPPSKQSLLFCPKSKLHIHRAEISKIMRECQEESFWKRALPFSLVSMLVTQGLVYQGYLAANSRFGSLPKVALAGLLGFGLGKVSYIGVCQSKFHFFEDQLRGAGFGPQHNRHCLLTCEECKIKHGLSEKGDSQPSAS

Target ORF information:

RefSeq Version	NM_001014446.3
Organism	Homo sapiens(human)
Definition	Homo sapiens OCIA domain containing 2 (OCIAD2), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001014446.3

ORF Insert Sequence:

ATGGCTTCAG CGTCTGCTCG TGGAAACCAA GATAAAGATG CCCATTTTCC ACCACCAAGC 
AAGCAGAGCC TGTTGTTTTG TCCAAAATCA AAACTGCACA TCCACAGAGC AGAGATCTCA 
AAGATTATGC GAGAATGTCA GGAAGAAAGT TTCTGGAAGA GAGCTCTGCC TTTTTCTCTT 
GTAAGCATGC TTGTCACCCA GGGACTAGTC TACCAAGGTT ATTTGGCAGC TAATTCTAGA 
TTTGGATCAT TGCCCAAAGT TGCACTTGCT GGTCTCTTGG GATTTGGCCT TGGAAAGGTA 
TCATACATAG GAGTATGCCA GAGTAAATTC CATTTTTTTG AAGATCAGCT CCGTGGGGCT 
GGTTTTGGTC CACAGCATAA CAGGCACTGC CTCCTTACCT GTGAGGAATG CAAAATAAAG 
CATGGATTAA GTGAGAAGGG AGACTCTCAG CCTTCAGCTT CCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

OCIAD2 ( NM_001286773.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001273702.1 Homo sapiens OCIA domain containing 2 (OCIAD2), transcript variant 3, mRNA.

Price & Availability↑

CloneID	OHu05711
Clone ID Related Accession (Same CDS sequence)	NM_001286773.1 , NM_152398.3
Accession Version	NM_001286773.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 300bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2018-12-22
Organism	Homo sapiens(human)
Product	OCIA domain-containing protein 2 isoform 2
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BI546814.1, W68799.1, BC032808.1 and BG748993.1. Transcript Variant: This variant (3) differs in the 5' UTR and lacks an exon in the central coding region, which results in a frameshift, compared to variant 1. The encoded isoform (2) has a shorter and distinct C-terminus, compared to isoform 1. Both variants 2 and 3 encode the same isoform. ##Evidence-Data-START## Transcript exon combination :: W68799.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2159080 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGCTTCAG CGTCTGCTCG TGGAAACCAA GATAAAGATG CCCATTTTCC ACCACCAAGC 
AAGCAGAGCC TGTTGTTTTG TCCAAAATCA AAACTGCACA TCCACAGAGC AGAGATCTCA 
AAGATTATGC GAGAATGTCA GGAAGAAAGT TTCTGGAAGA GAGCTCTGCC TTTTTCTCTT 
GTAAGCATGC TTGTCACCCA GGGACTAGTC TACCAAGGTT ATTTGGCAGC TAATTCTAGA 
TTTGGATCAT TGCCCAAAGT TGCACGCACT GCCTCCTTAC CTGTGAGGAA TGCAAAATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001273702.1
CDS	257..556
Translation	MASASARGNQDKDAHFPPPSKQSLLFCPKSKLHIHRAEISKIMRECQEESFWKRALPFSLVSMLVTQGLVYQGYLAANSRFGSLPKVARTASLPVRNAK

Target ORF information:

RefSeq Version	NM_001286773.1
Organism	Homo sapiens(human)
Definition	Homo sapiens OCIA domain containing 2 (OCIAD2), transcript variant 3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001286773.1

ORF Insert Sequence:

ATGGCTTCAG CGTCTGCTCG TGGAAACCAA GATAAAGATG CCCATTTTCC ACCACCAAGC 
AAGCAGAGCC TGTTGTTTTG TCCAAAATCA AAACTGCACA TCCACAGAGC AGAGATCTCA 
AAGATTATGC GAGAATGTCA GGAAGAAAGT TTCTGGAAGA GAGCTCTGCC TTTTTCTCTT 
GTAAGCATGC TTGTCACCCA GGGACTAGTC TACCAAGGTT ATTTGGCAGC TAATTCTAGA 
TTTGGATCAT TGCCCAAAGT TGCACGCACT GCCTCCTTAC CTGTGAGGAA TGCAAAATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

OCIAD2 ( NM_152398.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_689611.1 Homo sapiens OCIA domain containing 2 (OCIAD2), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu05711
Clone ID Related Accession (Same CDS sequence)	NM_001286773.1 , NM_152398.3
Accession Version	NM_152398.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 300bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2018-12-22
Organism	Homo sapiens(human)
Product	OCIA domain-containing protein 2 isoform 2
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BI546814.1, BC032808.1 and BG748993.1. On Nov 15, 2013 this sequence version replaced NM_152398.2. Transcript Variant: This variant (2) lacks an exon in the central coding region, which results in a frameshift, compared to variant 1. The encoded isoform (2) has a shorter and distinct C-terminus, compared to isoform 1. Both variants 2 and 3 encode the same isoform. ##Evidence-Data-START## Transcript exon combination :: BC032808.1, BG167015.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2142348, SAMEA2154405 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGCTTCAG CGTCTGCTCG TGGAAACCAA GATAAAGATG CCCATTTTCC ACCACCAAGC 
AAGCAGAGCC TGTTGTTTTG TCCAAAATCA AAACTGCACA TCCACAGAGC AGAGATCTCA 
AAGATTATGC GAGAATGTCA GGAAGAAAGT TTCTGGAAGA GAGCTCTGCC TTTTTCTCTT 
GTAAGCATGC TTGTCACCCA GGGACTAGTC TACCAAGGTT ATTTGGCAGC TAATTCTAGA 
TTTGGATCAT TGCCCAAAGT TGCACGCACT GCCTCCTTAC CTGTGAGGAA TGCAAAATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_689611.1
CDS	234..533
Translation	MASASARGNQDKDAHFPPPSKQSLLFCPKSKLHIHRAEISKIMRECQEESFWKRALPFSLVSMLVTQGLVYQGYLAANSRFGSLPKVARTASLPVRNAK

Target ORF information:

RefSeq Version	NM_152398.3
Organism	Homo sapiens(human)
Definition	Homo sapiens OCIA domain containing 2 (OCIAD2), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_152398.3

ORF Insert Sequence:

ATGGCTTCAG CGTCTGCTCG TGGAAACCAA GATAAAGATG CCCATTTTCC ACCACCAAGC 
AAGCAGAGCC TGTTGTTTTG TCCAAAATCA AAACTGCACA TCCACAGAGC AGAGATCTCA 
AAGATTATGC GAGAATGTCA GGAAGAAAGT TTCTGGAAGA GAGCTCTGCC TTTTTCTCTT 
GTAAGCATGC TTGTCACCCA GGGACTAGTC TACCAAGGTT ATTTGGCAGC TAATTCTAGA 
TTTGGATCAT TGCCCAAAGT TGCACGCACT GCCTCCTTAC CTGTGAGGAA TGCAAAATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

OCIAD2 ( NM_001286774.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001273703.1 Homo sapiens OCIA domain containing 2 (OCIAD2), transcript variant 4, mRNA.

Price & Availability↑

CloneID	OHu05712
Clone ID Related Accession (Same CDS sequence)	NM_001286774.1
Accession Version	NM_001286774.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 279bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2018-12-22
Organism	Homo sapiens(human)
Product	OCIA domain-containing protein 2 isoform 3
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BI546814.1, BU508058.1 and BG748993.1. Transcript Variant: This variant (4) differs in its 5' UTR and initiates translation at a downstream start codon, compared to variant 1. The encoded isoform (3) has a shorter N-terminus, compared to isoform 1. ##Evidence-Data-START## Transcript exon combination :: SRR1163655.704216.1, SRR1163658.182804.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2467146 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGCTTGTCA CCCAGGGACT AGTCTACCAA GGTTATTTGG CAGCTAATTC TAGATTTGGA 
TCATTGCCCA AAGTTGCACT TGCTGGTCTC TTGGGATTTG GCCTTGGAAA GGTATCATAC 
ATAGGAGTAT GCCAGAGTAA ATTCCATTTT TTTGAAGATC AGCTCCGTGG GGCTGGTTTT 
GGTCCACAGC ATAACAGGCA CTGCCTCCTT ACCTGTGAGG AATGCAAAAT AAAGCATGGA 
TTAAGTGAGA AGGGAGACTC TCAGCCTTCA GCTTCCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001273703.1
CDS	323..601
Translation	MLVTQGLVYQGYLAANSRFGSLPKVALAGLLGFGLGKVSYIGVCQSKFHFFEDQLRGAGFGPQHNRHCLLTCEECKIKHGLSEKGDSQPSAS

Target ORF information:

RefSeq Version	NM_001286774.1
Organism	Homo sapiens(human)
Definition	Homo sapiens OCIA domain containing 2 (OCIAD2), transcript variant 4, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001286774.1

ORF Insert Sequence:

ATGCTTGTCA CCCAGGGACT AGTCTACCAA GGTTATTTGG CAGCTAATTC TAGATTTGGA 
TCATTGCCCA AAGTTGCACT TGCTGGTCTC TTGGGATTTG GCCTTGGAAA GGTATCATAC 
ATAGGAGTAT GCCAGAGTAA ATTCCATTTT TTTGAAGATC AGCTCCGTGG GGCTGGTTTT 
GGTCCACAGC ATAACAGGCA CTGCCTCCTT ACCTGTGAGG AATGCAAAAT AAAGCATGGA 
TTAAGTGAGA AGGGAGACTC TCAGCCTTCA GCTTCCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

OCIAD2 suppressed tumor growth and invasion via AKT pathway in Hepatocelluar carcinoma.
Carcinogenesis38(9)910-919(2017 Sep)
Wu D,Yang X,Peng H,Guo D,Zhao W,Zhao C,Zhou X

OCIAD2 activates ?-secretase to enhance amyloid ? production by interacting with nicastrin.
Cellular and molecular life sciences : CMLS71(13)2561-76(2014 Jul)
Han J,Jung S,Jang J,Kam TI,Choi H,Kim BJ,Nah J,Jo DG,Nakagawa T,Nishimura M,Jung YK

Pathway bridge based multiobjective optimization approach for lurking pathway prediction.
BioMed research international2014351095(2014)
Zhang R,Zhao C,Xiong Z,Zhou X

Increased expression of OCIA domain containing 2 during stepwise progression of ovarian mucinous tumor.
Pathology international62(7)471-6(2012 Jul)
Nagata C,Kobayashi H,Sakata A,Satomi K,Minami Y,Morishita Y,Ohara R,Yoshikawa H,Arai Y,Nishida M,Noguchi M

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OCIAD2 cDNA ORF clone, Homo sapiens(human)

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Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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