CD200R1 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	CD200R1
Entrez Gene ID	131450
Full Name	CD200 receptor 1
Synonyms	CD200R,HCRTR2,MOX2R,OX2R
General protein information	Preferred Names CD200 receptor 1 Names cell surface glycoprotein CD200 receptor 1 CD200 cell surface glycoprotein receptor MOX2 receptor cell surface glycoprotein OX2 receptor 1 cell surface glycoprotein receptor CD200
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 3 Map Location: 3q13.2
Summary	This gene encodes a receptor for the OX-2 membrane glycoprotein. Both the receptor and substrate are cell surface glycoproteins containing two immunoglobulin-like domains. This receptor is restricted to the surfaces of myeloid lineage cells and the receptor-substrate interaction may function as a myeloid downregulatory signal. Mouse studies of a related gene suggest that this interaction may control myeloid function in a tissue-specific manner. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Jul 2008].
Disorder MIM:	607546

mRNA and Protein(s)

mRNA	Protein	Name
NM_138939.2	NP_620385.1	cell surface glycoprotein CD200 receptor 1 isoform b precursor
NM_138940.3	NP_620386.1	cell surface glycoprotein CD200 receptor 1 isoform c precursor
NM_170780.2	NP_740750.1	cell surface glycoprotein CD200 receptor 1 isoform d precursor
NM_138806.4	NP_620161.1	cell surface glycoprotein CD200 receptor 1 isoform a precursor
NM_138939.3	NP_620385.1	cell surface glycoprotein CD200 receptor 1 isoform b precursor
NM_138940.2	NP_620386.1	cell surface glycoprotein CD200 receptor 1 isoform c precursor
NM_138806.3	NP_620161.1	cell surface glycoprotein CD200 receptor 1 isoform a precursor
NM_170780.3	NP_740750.1	cell surface glycoprotein CD200 receptor 1 isoform d precursor

Pathways from BioSystems

Homologies

Pan troglodytes (chimpanzee)	CD200R1	XP_001156654.1
Bos taurus (cattle)	CD200R1	XP_002684796.3
Xenopus tropicalis (tropical clawed frog)	LOC100485346	XP_002940963.1
Canis lupus familiaris (dog)	CD200R1	XP_545099.2
Mus musculus (house mouse)	Cd200r1	NP_067300.1
Rattus norvegicus (Norway rat)	Cd200r1	NP_076443.1
Gallus gallus (chicken)	CD200R1	NP_001072952.1
Homo sapiens (human)	CD200R1	NP_620161.1
	CD200R1	XP_001105494.1
Xenopus tropicalis (tropical clawed frog)	LOC101731740	XP_004912495.1
Xenopus tropicalis (tropical clawed frog)	LOC101731855	XP_004912497.1
Bos taurus (cattle)	CD200R1L	NP_001092844.1
Gallus gallus (chicken)	CD200R1L	NP_001025953.2
Xenopus tropicalis (tropical clawed frog)	LOC100127716	NP_001106521.1
Xenopus tropicalis (tropical clawed frog)	LOC101731799	XP_004912496.1

Gene Ontology
Bibliography

Related articles in PubMed

Gingival Tissue Inflammation Promotes Increased Matrix Metalloproteinase-12 Production by CD200R
Bj?rnfot Holmstr?m S, Clark R, Zwicker S, Bureik D, Kvedaraite E, Bernasconi E, Nguyen Hoang AT, Johannsen G, Marsland BJ, Bostr?m EA, Svensson M
Journal of immunology (Baltimore, Md. : 1950)199(12)4023-4035(2017 Dec)

A CD200R-CD28 fusion protein appropriates an inhibitory signal to enhance T-cell function and therapy of murine leukemia.
Oda SK, Daman AW, Garcia NM, Wagener F, Schmitt TM, Tan X, Chapuis AG, Greenberg PD
Blood130(22)2410-2419(2017 11)

Changes in expression of the CD200 tolerance-signaling molecule and its receptor (CD200R) by villus trophoblasts during first trimester missed abortion and in chronic histiocytic intervillositis.
Clark DA, Dmetrichuk JM, McCready E, Dhesy-Thind S, Arredondo JL
American journal of reproductive immunology (New York, N.Y. : 1989)78(1)(2017 Jul)

The immunoglobulin superfamily member CD200R identifies cells involved in type 2 immune responses.
Blom LH, Martel BC, Larsen LF, Hansen CV, Christensen MP, Juel-Berg N, Litman T, Poulsen LK
Allergy72(7)1081-1090(2017 Jul)

Reduced expression of monocyte CD200R is associated with enhanced proinflammatory cytokine production in sarcoidosis.
Fraser SD, Sadofsky LR, Kaye PM, Hart SP
Scientific reports638689(2016 Dec)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

MMP12-producing monocyte-derived cells in gingival tissue of periodontitis patients also had reduced CD200R surface levels. Treatment with a CD200R ligand reduced CSF2-induced MMP12 production in these cells. This novel association of the CD200/CD200R pathway with MMP12 production by monocyte-derived cells may play a key role in PD progression.
Title: Gingival Tissue Inflammation Promotes Increased Matrix Metalloproteinase-12 Production by CD200R

Coexpression of CD200R-CD28 enhances function in WT1-specific T-cell receptor - transduced human primary T cells.
Title: A CD200R-CD28 fusion protein appropriates an inhibitory signal to enhance T-cell function and therapy of murine leukemia.

Our findings suggest a promising role of CD200R as a prognostic marker in predicting elevated recurrence and reduced survival, and a potential therapeutic target in treating hepatocellular carcinoma.
Title: CD200R, a co-inhibitory receptor on immune cells, predicts the prognosis of human hepatocellular carcinoma.

we revealed a critical role for CD200R signaling in limiting the growth and metastasis of CD200(+) tumors.
Title: A Critical Role for CD200R Signaling in Limiting the Growth and Metastasis of CD200+ Melanoma.

Constitutively expressed Siglec-9 inhibits LPS-induced CCR7, but enhances IL-4-induced CD200R expression in human macrophages.
Title: Constitutively expressed Siglec-9 inhibits LPS-induced CCR7, but enhances IL-4-induced CD200R expression in human macrophages.

The following CD200R1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the CD200R1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu23973	NM_170780.3 Latest version!	Homo sapiens CD200 receptor 1 (CD200R1), transcript variant 4, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$99.50-$139.30 $199.00
OHu24067	NM_138806.4 Latest version!	Homo sapiens CD200 receptor 1 (CD200R1), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$189.50-$265.30 $379.00
OHu23639	NM_138940.3 Latest version!	Homo sapiens CD200 receptor 1 (CD200R1), transcript variant 3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$69.30 $99.00
OHu23772	NM_138939.3 Latest version!	Homo sapiens CD200 receptor 1 (CD200R1), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$69.30 $99.00
View Old Accession Versions >>
OHu23772	NM_138939.2	Homo sapiens CD200 receptor 1 (CD200R1), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$69.30 $99.00
OHu23639	NM_138940.2	Homo sapiens CD200 receptor 1 (CD200R1), transcript variant 3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$69.30 $99.00
OHu24067	NM_138806.3	Homo sapiens CD200 receptor 1 (CD200R1), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$189.50-$265.30 $379.00
OHu23973	NM_170780.2	Homo sapiens CD200 receptor 1 (CD200R1), transcript variant 4, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$99.50-$139.30 $199.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

CD200R1 ( NM_170780.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_740750.1 Homo sapiens CD200 receptor 1 (CD200R1), transcript variant 4, mRNA.

Price & Availability↑

CloneID	OHu23973
Clone ID Related Accession (Same CDS sequence)	NM_170780.2 , NM_170780.3
Accession Version	NM_170780.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 978bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-02-15
Organism	Homo sapiens(human)
Product	cell surface glycoprotein CD200 receptor 1 isoform d precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AK126349.1 and AF497548.1. On Jan 26, 2004 this sequence version replaced NM_170780.1. Transcript Variant: This variant (4) utilizes an alternate splice site in the coding region, compared to variant 1. This results in a shorter protein (isoform d), compared to isoform a. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK126349.1, AF283760.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1968968 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGCTCTGCC CTTGGAGAAC TGCTAACCTA GGGCTACTGT TGATTTTGAC TATCTTCTTA 
GTGGCCGCTT CAAGCAGTTT ATGTATGGAT GAAAAACAGA TTACACAGAA CTACTCGAAA 
GTACTCGCAG AAGTTAACAC TTCATGGCCT GTAAAGATGG CTACAAATGC TGTGCTTTGT 
TGCCCTCCTA TCGCATTAAG AAATTTGATC ATAATAACAT GGGAAATAAT CCTGAGAGGC 
CAGCCTTCCT GCACAAAAGC CTACAAGAAA GAAACAAATG AGACCAAGGA AACCAACTGT 
ACTGATGAGA GAATAACCTG GGTCTCCAGA CCTGATCAGA ATTCGGACCT TCAGATTCGT 
ACCGTGGCCA TCACTCATGA CGGGTATTAC AGATGCATAA TGGTAACACC TGATGGGAAT 
TTCCATCGTG GATATCACCT CCAAGTGTTA GTTACACCTG AAGTGACCCT GTTTCAAAAC 
AGGAATAGAA CTGCAGTATG CAAGGCAGTT GCAGGGAAGC CAGCTGCGCA TATCTCCTGG 
ATCCCAGAGG GCGATTGTGC CACTAAGCAA GAATACTGGA GCAATGGCAC AGTGACTGTT 
AAGAGTACAT GCCACTGGGA GGTCCACAAT GTGTCTACCG TGACCTGCCA CGTCTCCCAT 
TTGACTGGCA ACAAGAGTCT GTACATAGAG CTACTTCCTG TTCCAGGTGC CAAAAAATCA 
GCAAAATTAT ATATTCCATA TATCATCCTT ACTATTATTA TTTTGACCAT CGTGGGATTC 
ATTTGGTTGT TGAAAGTCAA TGGCTGCAGA AAATATAAAT TGAATAAAAC AGAATCTACT 
CCAGTTGTTG AGGAGGATGA AATGCAGCCC TATGCCAGCT ACACAGAGAA GAACAATCCT 
CTCTATGATA CTACAAACAA GGTGAAGGCA TCTGAGGCAT TACAAAGTGA AGTTGACACA 
GACCTCCATA CTTTATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_740750.1
CDS	234..1211
Translation	MLCPWRTANLGLLLILTIFLVAASSSLCMDEKQITQNYSKVLAEVNTSWPVKMATNAVLCCPPIALRNLIIITWEIILRGQPSCTKAYKKETNETKETNCTDERITWVSRPDQNSDLQIRTVAITHDGYYRCIMVTPDGNFHRGYHLQVLVTPEVTLFQNRNRTAVCKAVAGKPAAHISWIPEGDCATKQEYWSNGTVTVKSTCHWEVHNVSTVTCHVSHLTGNKSLYIELLPVPGAKKSAKLYIPYIILTIIILTIVGFIWLLKVNGCRKYKLNKTESTPVVEEDEMQPYASYTEKNNPLYDTTNKVKASEALQSEVDTDLHTL

Target ORF information:

RefSeq Version	NM_170780.2
Organism	Homo sapiens(human)
Definition	Homo sapiens CD200 receptor 1 (CD200R1), transcript variant 4, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_170780.2

ORF Insert Sequence:

ATGCTCTGCC CTTGGAGAAC TGCTAACCTA GGGCTACTGT TGATTTTGAC TATCTTCTTA 
GTGGCCGCTT CAAGCAGTTT ATGTATGGAT GAAAAACAGA TTACACAGAA CTACTCGAAA 
GTACTCGCAG AAGTTAACAC TTCATGGCCT GTAAAGATGG CTACAAATGC TGTGCTTTGT 
TGCCCTCCTA TCGCATTAAG AAATTTGATC ATAATAACAT GGGAAATAAT CCTGAGAGGC 
CAGCCTTCCT GCACAAAAGC CTACAAGAAA GAAACAAATG AGACCAAGGA AACCAACTGT 
ACTGATGAGA GAATAACCTG GGTCTCCAGA CCTGATCAGA ATTCGGACCT TCAGATTCGT 
ACCGTGGCCA TCACTCATGA CGGGTATTAC AGATGCATAA TGGTAACACC TGATGGGAAT 
TTCCATCGTG GATATCACCT CCAAGTGTTA GTTACACCTG AAGTGACCCT GTTTCAAAAC 
AGGAATAGAA CTGCAGTATG CAAGGCAGTT GCAGGGAAGC CAGCTGCGCA TATCTCCTGG 
ATCCCAGAGG GCGATTGTGC CACTAAGCAA GAATACTGGA GCAATGGCAC AGTGACTGTT 
AAGAGTACAT GCCACTGGGA GGTCCACAAT GTGTCTACCG TGACCTGCCA CGTCTCCCAT 
TTGACTGGCA ACAAGAGTCT GTACATAGAG CTACTTCCTG TTCCAGGTGC CAAAAAATCA 
GCAAAATTAT ATATTCCATA TATCATCCTT ACTATTATTA TTTTGACCAT CGTGGGATTC 
ATTTGGTTGT TGAAAGTCAA TGGCTGCAGA AAATATAAAT TGAATAAAAC AGAATCTACT 
CCAGTTGTTG AGGAGGATGA AATGCAGCCC TATGCCAGCT ACACAGAGAA GAACAATCCT 
CTCTATGATA CTACAAACAA GGTGAAGGCA TCTGAGGCAT TACAAAGTGA AGTTGACACA 
GACCTCCATA CTTTATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

CD200R1 ( NM_170780.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_740750.1 Homo sapiens CD200 receptor 1 (CD200R1), transcript variant 4, mRNA.

Price & Availability↑

CloneID	OHu23973
Clone ID Related Accession (Same CDS sequence)	NM_170780.2 , NM_170780.3
Accession Version	NM_170780.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 978bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2020-01-03
Organism	Homo sapiens(human)
Product	cell surface glycoprotein CD200 receptor 1 isoform d precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AC074044.8, AK126349.1 and AF497548.1. On May 31, 2019 this sequence version replaced NM_170780.2. Transcript Variant: This variant (4) utilizes an alternate splice site in the coding region, compared to variant 1. This results in a shorter protein (isoform d), compared to isoform a. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK126349.1, AF497548.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1968968 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGCTCTGCC CTTGGAGAAC TGCTAACCTA GGGCTACTGT TGATTTTGAC TATCTTCTTA 
GTGGCCGCTT CAAGCAGTTT ATGTATGGAT GAAAAACAGA TTACACAGAA CTACTCGAAA 
GTACTCGCAG AAGTTAACAC TTCATGGCCT GTAAAGATGG CTACAAATGC TGTGCTTTGT 
TGCCCTCCTA TCGCATTAAG AAATTTGATC ATAATAACAT GGGAAATAAT CCTGAGAGGC 
CAGCCTTCCT GCACAAAAGC CTACAAGAAA GAAACAAATG AGACCAAGGA AACCAACTGT 
ACTGATGAGA GAATAACCTG GGTCTCCAGA CCTGATCAGA ATTCGGACCT TCAGATTCGT 
ACCGTGGCCA TCACTCATGA CGGGTATTAC AGATGCATAA TGGTAACACC TGATGGGAAT 
TTCCATCGTG GATATCACCT CCAAGTGTTA GTTACACCTG AAGTGACCCT GTTTCAAAAC 
AGGAATAGAA CTGCAGTATG CAAGGCAGTT GCAGGGAAGC CAGCTGCGCA TATCTCCTGG 
ATCCCAGAGG GCGATTGTGC CACTAAGCAA GAATACTGGA GCAATGGCAC AGTGACTGTT 
AAGAGTACAT GCCACTGGGA GGTCCACAAT GTGTCTACCG TGACCTGCCA CGTCTCCCAT 
TTGACTGGCA ACAAGAGTCT GTACATAGAG CTACTTCCTG TTCCAGGTGC CAAAAAATCA 
GCAAAATTAT ATATTCCATA TATCATCCTT ACTATTATTA TTTTGACCAT CGTGGGATTC 
ATTTGGTTGT TGAAAGTCAA TGGCTGCAGA AAATATAAAT TGAATAAAAC AGAATCTACT 
CCAGTTGTTG AGGAGGATGA AATGCAGCCC TATGCCAGCT ACACAGAGAA GAACAATCCT 
CTCTATGATA CTACAAACAA GGTGAAGGCA TCTGAGGCAT TACAAAGTGA AGTTGACACA 
GACCTCCATA CTTTATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_740750.1
CDS	247..1224
Translation	MLCPWRTANLGLLLILTIFLVAASSSLCMDEKQITQNYSKVLAEVNTSWPVKMATNAVLCCPPIALRNLIIITWEIILRGQPSCTKAYKKETNETKETNCTDERITWVSRPDQNSDLQIRTVAITHDGYYRCIMVTPDGNFHRGYHLQVLVTPEVTLFQNRNRTAVCKAVAGKPAAHISWIPEGDCATKQEYWSNGTVTVKSTCHWEVHNVSTVTCHVSHLTGNKSLYIELLPVPGAKKSAKLYIPYIILTIIILTIVGFIWLLKVNGCRKYKLNKTESTPVVEEDEMQPYASYTEKNNPLYDTTNKVKASEALQSEVDTDLHTL

Target ORF information:

RefSeq Version	NM_170780.3
Organism	Homo sapiens(human)
Definition	Homo sapiens CD200 receptor 1 (CD200R1), transcript variant 4, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_170780.3

ORF Insert Sequence:

ATGCTCTGCC CTTGGAGAAC TGCTAACCTA GGGCTACTGT TGATTTTGAC TATCTTCTTA 
GTGGCCGCTT CAAGCAGTTT ATGTATGGAT GAAAAACAGA TTACACAGAA CTACTCGAAA 
GTACTCGCAG AAGTTAACAC TTCATGGCCT GTAAAGATGG CTACAAATGC TGTGCTTTGT 
TGCCCTCCTA TCGCATTAAG AAATTTGATC ATAATAACAT GGGAAATAAT CCTGAGAGGC 
CAGCCTTCCT GCACAAAAGC CTACAAGAAA GAAACAAATG AGACCAAGGA AACCAACTGT 
ACTGATGAGA GAATAACCTG GGTCTCCAGA CCTGATCAGA ATTCGGACCT TCAGATTCGT 
ACCGTGGCCA TCACTCATGA CGGGTATTAC AGATGCATAA TGGTAACACC TGATGGGAAT 
TTCCATCGTG GATATCACCT CCAAGTGTTA GTTACACCTG AAGTGACCCT GTTTCAAAAC 
AGGAATAGAA CTGCAGTATG CAAGGCAGTT GCAGGGAAGC CAGCTGCGCA TATCTCCTGG 
ATCCCAGAGG GCGATTGTGC CACTAAGCAA GAATACTGGA GCAATGGCAC AGTGACTGTT 
AAGAGTACAT GCCACTGGGA GGTCCACAAT GTGTCTACCG TGACCTGCCA CGTCTCCCAT 
TTGACTGGCA ACAAGAGTCT GTACATAGAG CTACTTCCTG TTCCAGGTGC CAAAAAATCA 
GCAAAATTAT ATATTCCATA TATCATCCTT ACTATTATTA TTTTGACCAT CGTGGGATTC 
ATTTGGTTGT TGAAAGTCAA TGGCTGCAGA AAATATAAAT TGAATAAAAC AGAATCTACT 
CCAGTTGTTG AGGAGGATGA AATGCAGCCC TATGCCAGCT ACACAGAGAA GAACAATCCT 
CTCTATGATA CTACAAACAA GGTGAAGGCA TCTGAGGCAT TACAAAGTGA AGTTGACACA 
GACCTCCATA CTTTATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

CD200R1 ( NM_138806.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_620161.1 Homo sapiens CD200 receptor 1 (CD200R1), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu24067
Clone ID Related Accession (Same CDS sequence)	NM_138806.4 , NM_138806.3
Accession Version	NM_138806.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1047bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-30
Organism	Homo sapiens(human)
Product	cell surface glycoprotein CD200 receptor 1 isoform a precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AC074044.8, AY358910.1, AF495380.1 and AK126349.1. On Nov 22, 2018 this sequence version replaced NM_138806.3. Transcript Variant: This variant (1) represents the longest transcript variant and encodes the longest isoform (a). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AY358910.1, SRR1163658.245221.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000308611.8/ ENSP00000311035.3 RefSeq Select criteria :: based on conservation, expression, longest protein ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGCTCTGCC CTTGGAGAAC TGCTAACCTA GGGCTACTGT TGATTTTGAC TATCTTCTTA 
GTGGCCGAAG CGGAGGGTGC TGCTCAACCA AACAACTCAT TAATGCTGCA AACTAGCAAG 
GAGAATCATG CTTTAGCTTC AAGCAGTTTA TGTATGGATG AAAAACAGAT TACACAGAAC 
TACTCGAAAG TACTCGCAGA AGTTAACACT TCATGGCCTG TAAAGATGGC TACAAATGCT 
GTGCTTTGTT GCCCTCCTAT CGCATTAAGA AATTTGATCA TAATAACATG GGAAATAATC 
CTGAGAGGCC AGCCTTCCTG CACAAAAGCC TACAAGAAAG AAACAAATGA GACCAAGGAA 
ACCAACTGTA CTGATGAGAG AATAACCTGG GTCTCCAGAC CTGATCAGAA TTCGGACCTT 
CAGATTCGTA CCGTGGCCAT CACTCATGAC GGGTATTACA GATGCATAAT GGTAACACCT 
GATGGGAATT TCCATCGTGG ATATCACCTC CAAGTGTTAG TTACACCTGA AGTGACCCTG 
TTTCAAAACA GGAATAGAAC TGCAGTATGC AAGGCAGTTG CAGGGAAGCC AGCTGCGCAT 
ATCTCCTGGA TCCCAGAGGG CGATTGTGCC ACTAAGCAAG AATACTGGAG CAATGGCACA 
GTGACTGTTA AGAGTACATG CCACTGGGAG GTCCACAATG TGTCTACCGT GACCTGCCAC 
GTCTCCCATT TGACTGGCAA CAAGAGTCTG TACATAGAGC TACTTCCTGT TCCAGGTGCC 
AAAAAATCAG CAAAATTATA TATTCCATAT ATCATCCTTA CTATTATTAT TTTGACCATC 
GTGGGATTCA TTTGGTTGTT GAAAGTCAAT GGCTGCAGAA AATATAAATT GAATAAAACA 
GAATCTACTC CAGTTGTTGA GGAGGATGAA ATGCAGCCCT ATGCCAGCTA CACAGAGAAG 
AACAATCCTC TCTATGATAC TACAAACAAG GTGAAGGCAT CTGAGGCATT ACAAAGTGAA 
GTTGACACAG ACCTCCATAC TTTATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_620161.1
CDS	247..1293
Translation	MLCPWRTANLGLLLILTIFLVAEAEGAAQPNNSLMLQTSKENHALASSSLCMDEKQITQNYSKVLAEVNTSWPVKMATNAVLCCPPIALRNLIIITWEIILRGQPSCTKAYKKETNETKETNCTDERITWVSRPDQNSDLQIRTVAITHDGYYRCIMVTPDGNFHRGYHLQVLVTPEVTLFQNRNRTAVCKAVAGKPAAHISWIPEGDCATKQEYWSNGTVTVKSTCHWEVHNVSTVTCHVSHLTGNKSLYIELLPVPGAKKSAKLYIPYIILTIIILTIVGFIWLLKVNGCRKYKLNKTESTPVVEEDEMQPYASYTEKNNPLYDTTNKVKASEALQSEVDTDLHTL

Target ORF information:

RefSeq Version	NM_138806.4
Organism	Homo sapiens(human)
Definition	Homo sapiens CD200 receptor 1 (CD200R1), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_138806.4

ORF Insert Sequence:

ATGCTCTGCC CTTGGAGAAC TGCTAACCTA GGGCTACTGT TGATTTTGAC TATCTTCTTA 
GTGGCCGAAG CGGAGGGTGC TGCTCAACCA AACAACTCAT TAATGCTGCA AACTAGCAAG 
GAGAATCATG CTTTAGCTTC AAGCAGTTTA TGTATGGATG AAAAACAGAT TACACAGAAC 
TACTCGAAAG TACTCGCAGA AGTTAACACT TCATGGCCTG TAAAGATGGC TACAAATGCT 
GTGCTTTGTT GCCCTCCTAT CGCATTAAGA AATTTGATCA TAATAACATG GGAAATAATC 
CTGAGAGGCC AGCCTTCCTG CACAAAAGCC TACAAGAAAG AAACAAATGA GACCAAGGAA 
ACCAACTGTA CTGATGAGAG AATAACCTGG GTCTCCAGAC CTGATCAGAA TTCGGACCTT 
CAGATTCGTA CCGTGGCCAT CACTCATGAC GGGTATTACA GATGCATAAT GGTAACACCT 
GATGGGAATT TCCATCGTGG ATATCACCTC CAAGTGTTAG TTACACCTGA AGTGACCCTG 
TTTCAAAACA GGAATAGAAC TGCAGTATGC AAGGCAGTTG CAGGGAAGCC AGCTGCGCAT 
ATCTCCTGGA TCCCAGAGGG CGATTGTGCC ACTAAGCAAG AATACTGGAG CAATGGCACA 
GTGACTGTTA AGAGTACATG CCACTGGGAG GTCCACAATG TGTCTACCGT GACCTGCCAC 
GTCTCCCATT TGACTGGCAA CAAGAGTCTG TACATAGAGC TACTTCCTGT TCCAGGTGCC 
AAAAAATCAG CAAAATTATA TATTCCATAT ATCATCCTTA CTATTATTAT TTTGACCATC 
GTGGGATTCA TTTGGTTGTT GAAAGTCAAT GGCTGCAGAA AATATAAATT GAATAAAACA 
GAATCTACTC CAGTTGTTGA GGAGGATGAA ATGCAGCCCT ATGCCAGCTA CACAGAGAAG 
AACAATCCTC TCTATGATAC TACAAACAAG GTGAAGGCAT CTGAGGCATT ACAAAGTGAA 
GTTGACACAG ACCTCCATAC TTTATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

CD200R1 ( NM_138806.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_620161.1 Homo sapiens CD200 receptor 1 (CD200R1), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu24067
Clone ID Related Accession (Same CDS sequence)	NM_138806.4 , NM_138806.3
Accession Version	NM_138806.3	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1047bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-12-31
Organism	Homo sapiens(human)
Product	cell surface glycoprotein CD200 receptor 1 isoform a precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AY358910.1, AF495380.1 and AK126349.1. On Jan 26, 2004 this sequence version replaced NM_138806.2. Transcript Variant: This variant (1) represents the longest transcript variant and encodes the longest isoform (a). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AY358910.1, SRR1163658.245221.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGCTCTGCC CTTGGAGAAC TGCTAACCTA GGGCTACTGT TGATTTTGAC TATCTTCTTA 
GTGGCCGAAG CGGAGGGTGC TGCTCAACCA AACAACTCAT TAATGCTGCA AACTAGCAAG 
GAGAATCATG CTTTAGCTTC AAGCAGTTTA TGTATGGATG AAAAACAGAT TACACAGAAC 
TACTCGAAAG TACTCGCAGA AGTTAACACT TCATGGCCTG TAAAGATGGC TACAAATGCT 
GTGCTTTGTT GCCCTCCTAT CGCATTAAGA AATTTGATCA TAATAACATG GGAAATAATC 
CTGAGAGGCC AGCCTTCCTG CACAAAAGCC TACAAGAAAG AAACAAATGA GACCAAGGAA 
ACCAACTGTA CTGATGAGAG AATAACCTGG GTCTCCAGAC CTGATCAGAA TTCGGACCTT 
CAGATTCGTA CCGTGGCCAT CACTCATGAC GGGTATTACA GATGCATAAT GGTAACACCT 
GATGGGAATT TCCATCGTGG ATATCACCTC CAAGTGTTAG TTACACCTGA AGTGACCCTG 
TTTCAAAACA GGAATAGAAC TGCAGTATGC AAGGCAGTTG CAGGGAAGCC AGCTGCGCAT 
ATCTCCTGGA TCCCAGAGGG CGATTGTGCC ACTAAGCAAG AATACTGGAG CAATGGCACA 
GTGACTGTTA AGAGTACATG CCACTGGGAG GTCCACAATG TGTCTACCGT GACCTGCCAC 
GTCTCCCATT TGACTGGCAA CAAGAGTCTG TACATAGAGC TACTTCCTGT TCCAGGTGCC 
AAAAAATCAG CAAAATTATA TATTCCATAT ATCATCCTTA CTATTATTAT TTTGACCATC 
GTGGGATTCA TTTGGTTGTT GAAAGTCAAT GGCTGCAGAA AATATAAATT GAATAAAACA 
GAATCTACTC CAGTTGTTGA GGAGGATGAA ATGCAGCCCT ATGCCAGCTA CACAGAGAAG 
AACAATCCTC TCTATGATAC TACAAACAAG GTGAAGGCAT CTGAGGCATT ACAAAGTGAA 
GTTGACACAG ACCTCCATAC TTTATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_620161.1
CDS	234..1280
Translation	MLCPWRTANLGLLLILTIFLVAEAEGAAQPNNSLMLQTSKENHALASSSLCMDEKQITQNYSKVLAEVNTSWPVKMATNAVLCCPPIALRNLIIITWEIILRGQPSCTKAYKKETNETKETNCTDERITWVSRPDQNSDLQIRTVAITHDGYYRCIMVTPDGNFHRGYHLQVLVTPEVTLFQNRNRTAVCKAVAGKPAAHISWIPEGDCATKQEYWSNGTVTVKSTCHWEVHNVSTVTCHVSHLTGNKSLYIELLPVPGAKKSAKLYIPYIILTIIILTIVGFIWLLKVNGCRKYKLNKTESTPVVEEDEMQPYASYTEKNNPLYDTTNKVKASEALQSEVDTDLHTL

Target ORF information:

RefSeq Version	NM_138806.3
Organism	Homo sapiens(human)
Definition	Homo sapiens CD200 receptor 1 (CD200R1), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_138806.3

ORF Insert Sequence:

ATGCTCTGCC CTTGGAGAAC TGCTAACCTA GGGCTACTGT TGATTTTGAC TATCTTCTTA 
GTGGCCGAAG CGGAGGGTGC TGCTCAACCA AACAACTCAT TAATGCTGCA AACTAGCAAG 
GAGAATCATG CTTTAGCTTC AAGCAGTTTA TGTATGGATG AAAAACAGAT TACACAGAAC 
TACTCGAAAG TACTCGCAGA AGTTAACACT TCATGGCCTG TAAAGATGGC TACAAATGCT 
GTGCTTTGTT GCCCTCCTAT CGCATTAAGA AATTTGATCA TAATAACATG GGAAATAATC 
CTGAGAGGCC AGCCTTCCTG CACAAAAGCC TACAAGAAAG AAACAAATGA GACCAAGGAA 
ACCAACTGTA CTGATGAGAG AATAACCTGG GTCTCCAGAC CTGATCAGAA TTCGGACCTT 
CAGATTCGTA CCGTGGCCAT CACTCATGAC GGGTATTACA GATGCATAAT GGTAACACCT 
GATGGGAATT TCCATCGTGG ATATCACCTC CAAGTGTTAG TTACACCTGA AGTGACCCTG 
TTTCAAAACA GGAATAGAAC TGCAGTATGC AAGGCAGTTG CAGGGAAGCC AGCTGCGCAT 
ATCTCCTGGA TCCCAGAGGG CGATTGTGCC ACTAAGCAAG AATACTGGAG CAATGGCACA 
GTGACTGTTA AGAGTACATG CCACTGGGAG GTCCACAATG TGTCTACCGT GACCTGCCAC 
GTCTCCCATT TGACTGGCAA CAAGAGTCTG TACATAGAGC TACTTCCTGT TCCAGGTGCC 
AAAAAATCAG CAAAATTATA TATTCCATAT ATCATCCTTA CTATTATTAT TTTGACCATC 
GTGGGATTCA TTTGGTTGTT GAAAGTCAAT GGCTGCAGAA AATATAAATT GAATAAAACA 
GAATCTACTC CAGTTGTTGA GGAGGATGAA ATGCAGCCCT ATGCCAGCTA CACAGAGAAG 
AACAATCCTC TCTATGATAC TACAAACAAG GTGAAGGCAT CTGAGGCATT ACAAAGTGAA 
GTTGACACAG ACCTCCATAC TTTATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

CD200R1 ( NM_138940.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_620386.1 Homo sapiens CD200 receptor 1 (CD200R1), transcript variant 3, mRNA.

Price & Availability↑

CloneID	OHu23639
Clone ID Related Accession (Same CDS sequence)	NM_138940.3 , NM_138940.2
Accession Version	NM_138940.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 498bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2020-01-03
Organism	Homo sapiens(human)
Product	cell surface glycoprotein CD200 receptor 1 isoform c precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AC074044.8, AK126349.1 and AF497550.1. On May 31, 2019 this sequence version replaced NM_138940.2. Transcript Variant: This variant (3) contains multiple differences in the coding region, compared to variant 1. This results in a frameshift and early stop codon, as well as loss of an immunoglobulin and transmembrane domain in the protein (isoform c), compared to isoform a. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AF497550.1, DB239072.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1968968 [ECO:0000348] ##Evidence-Data-END##

ATGCTCTGCC CTTGGAGAAC TGCTAACCTA GGGCTACTGT TGATTTTGAC TATCTTCTTA 
GTGGCCGCTT CAAGCAGTTT ATGTATGGAT GAAAAACAGA TTACACAGAA CTACTCGAAA 
GTACTCGCAG AAGTTAACAC TTCATGGCCT GTAAAGATGG CTACAAATGC TGTGCTTTGT 
TGCCCTCCTA TCGCATTAAG AAATTTGATC ATAATAACAT GGGAAATAAT CCTGAGAGGC 
CAGCCTTCCT GCACAAAAGC CTACAAGAAA GAAACAAATG AGACCAAGGA AACCAACTGT 
ACTGATGAGA GAATAACCTG GGTCTCCAGA CCTGATCAGA ATTCGGACCT TCAGATTCGT 
ACCGTGGCCA TCACTCATGA CGGGTATTAC AGATGCATAA TGGTAACACC TGATGGGAAT 
TTCCATCGTG GATATCACCT CCAAGTGTTA GGTAAGGAGC ATCATATATT GAGGTATTTC 
ACATCACCAG ATTTGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_620386.1
CDS	247..744
Translation	MLCPWRTANLGLLLILTIFLVAASSSLCMDEKQITQNYSKVLAEVNTSWPVKMATNAVLCCPPIALRNLIIITWEIILRGQPSCTKAYKKETNETKETNCTDERITWVSRPDQNSDLQIRTVAITHDGYYRCIMVTPDGNFHRGYHLQVLGKEHHILRYFTSPDL

Target ORF information:

RefSeq Version	NM_138940.3
Organism	Homo sapiens(human)
Definition	Homo sapiens CD200 receptor 1 (CD200R1), transcript variant 3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_138940.3

ORF Insert Sequence:

ATGCTCTGCC CTTGGAGAAC TGCTAACCTA GGGCTACTGT TGATTTTGAC TATCTTCTTA 
GTGGCCGCTT CAAGCAGTTT ATGTATGGAT GAAAAACAGA TTACACAGAA CTACTCGAAA 
GTACTCGCAG AAGTTAACAC TTCATGGCCT GTAAAGATGG CTACAAATGC TGTGCTTTGT 
TGCCCTCCTA TCGCATTAAG AAATTTGATC ATAATAACAT GGGAAATAAT CCTGAGAGGC 
CAGCCTTCCT GCACAAAAGC CTACAAGAAA GAAACAAATG AGACCAAGGA AACCAACTGT 
ACTGATGAGA GAATAACCTG GGTCTCCAGA CCTGATCAGA ATTCGGACCT TCAGATTCGT 
ACCGTGGCCA TCACTCATGA CGGGTATTAC AGATGCATAA TGGTAACACC TGATGGGAAT 
TTCCATCGTG GATATCACCT CCAAGTGTTA GGTAAGGAGC ATCATATATT GAGGTATTTC 
ACATCACCAG ATTTGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

CD200R1 ( NM_138940.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_620386.1 Homo sapiens CD200 receptor 1 (CD200R1), transcript variant 3, mRNA.

Price & Availability↑

CloneID	OHu23639
Clone ID Related Accession (Same CDS sequence)	NM_138940.3 , NM_138940.2
Accession Version	NM_138940.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 498bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-02-16
Organism	Homo sapiens(human)
Product	cell surface glycoprotein CD200 receptor 1 isoform c precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AK126349.1 and AF497550.1. On Jun 24, 2005 this sequence version replaced NM_138940.1. Transcript Variant: This variant (3) contains multiple differences in the coding region, compared to variant 1. This results in a frameshift and early stop codon, as well as loss of an immunoglobulin and transmembrane domain in the protein (isoform c), compared to isoform a. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AF497550.1, DB239072.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1968968 [ECO:0000348] ##Evidence-Data-END##

ATGCTCTGCC CTTGGAGAAC TGCTAACCTA GGGCTACTGT TGATTTTGAC TATCTTCTTA 
GTGGCCGCTT CAAGCAGTTT ATGTATGGAT GAAAAACAGA TTACACAGAA CTACTCGAAA 
GTACTCGCAG AAGTTAACAC TTCATGGCCT GTAAAGATGG CTACAAATGC TGTGCTTTGT 
TGCCCTCCTA TCGCATTAAG AAATTTGATC ATAATAACAT GGGAAATAAT CCTGAGAGGC 
CAGCCTTCCT GCACAAAAGC CTACAAGAAA GAAACAAATG AGACCAAGGA AACCAACTGT 
ACTGATGAGA GAATAACCTG GGTCTCCAGA CCTGATCAGA ATTCGGACCT TCAGATTCGT 
ACCGTGGCCA TCACTCATGA CGGGTATTAC AGATGCATAA TGGTAACACC TGATGGGAAT 
TTCCATCGTG GATATCACCT CCAAGTGTTA GGTAAGGAGC ATCATATATT GAGGTATTTC 
ACATCACCAG ATTTGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_620386.1
CDS	234..731
Translation	MLCPWRTANLGLLLILTIFLVAASSSLCMDEKQITQNYSKVLAEVNTSWPVKMATNAVLCCPPIALRNLIIITWEIILRGQPSCTKAYKKETNETKETNCTDERITWVSRPDQNSDLQIRTVAITHDGYYRCIMVTPDGNFHRGYHLQVLGKEHHILRYFTSPDL

Target ORF information:

RefSeq Version	NM_138940.2
Organism	Homo sapiens(human)
Definition	Homo sapiens CD200 receptor 1 (CD200R1), transcript variant 3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_138940.2

ORF Insert Sequence:

ATGCTCTGCC CTTGGAGAAC TGCTAACCTA GGGCTACTGT TGATTTTGAC TATCTTCTTA 
GTGGCCGCTT CAAGCAGTTT ATGTATGGAT GAAAAACAGA TTACACAGAA CTACTCGAAA 
GTACTCGCAG AAGTTAACAC TTCATGGCCT GTAAAGATGG CTACAAATGC TGTGCTTTGT 
TGCCCTCCTA TCGCATTAAG AAATTTGATC ATAATAACAT GGGAAATAAT CCTGAGAGGC 
CAGCCTTCCT GCACAAAAGC CTACAAGAAA GAAACAAATG AGACCAAGGA AACCAACTGT 
ACTGATGAGA GAATAACCTG GGTCTCCAGA CCTGATCAGA ATTCGGACCT TCAGATTCGT 
ACCGTGGCCA TCACTCATGA CGGGTATTAC AGATGCATAA TGGTAACACC TGATGGGAAT 
TTCCATCGTG GATATCACCT CCAAGTGTTA GGTAAGGAGC ATCATATATT GAGGTATTTC 
ACATCACCAG ATTTGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

CD200R1 ( NM_138939.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_620385.1 Homo sapiens CD200 receptor 1 (CD200R1), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu23772
Clone ID Related Accession (Same CDS sequence)	NM_138939.2 , NM_138939.3
Accession Version	NM_138939.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 567bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2018-12-07
Organism	Homo sapiens(human)
Product	cell surface glycoprotein CD200 receptor 1 isoform b precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AK126349.1 and AF497549.1. On Jun 24, 2005 this sequence version replaced NM_138939.1. Transcript Variant: This variant (2) includes an alternate exon in the coding region, compared to variant 1. This results in a frameshift and early stop codon, as well as loss of an immunoglobulin and transmembrane domain in the protein (isoform b), compared to isoform a. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AF497549.1, AL712200.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END##

ATGCTCTGCC CTTGGAGAAC TGCTAACCTA GGGCTACTGT TGATTTTGAC TATCTTCTTA 
GTGGCCGAAG CGGAGGGTGC TGCTCAACCA AACAACTCAT TAATGCTGCA AACTAGCAAG 
GAGAATCATG CTTTAGCTTC AAGCAGTTTA TGTATGGATG AAAAACAGAT TACACAGAAC 
TACTCGAAAG TACTCGCAGA AGTTAACACT TCATGGCCTG TAAAGATGGC TACAAATGCT 
GTGCTTTGTT GCCCTCCTAT CGCATTAAGA AATTTGATCA TAATAACATG GGAAATAATC 
CTGAGAGGCC AGCCTTCCTG CACAAAAGCC TACAAGAAAG AAACAAATGA GACCAAGGAA 
ACCAACTGTA CTGATGAGAG AATAACCTGG GTCTCCAGAC CTGATCAGAA TTCGGACCTT 
CAGATTCGTA CCGTGGCCAT CACTCATGAC GGGTATTACA GATGCATAAT GGTAACACCT 
GATGGGAATT TCCATCGTGG ATATCACCTC CAAGTGTTAG GTAAGGAGCA TCATATATTG 
AGGTATTTCA CATCACCAGA TTTGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_620385.1
CDS	234..800
Translation	MLCPWRTANLGLLLILTIFLVAEAEGAAQPNNSLMLQTSKENHALASSSLCMDEKQITQNYSKVLAEVNTSWPVKMATNAVLCCPPIALRNLIIITWEIILRGQPSCTKAYKKETNETKETNCTDERITWVSRPDQNSDLQIRTVAITHDGYYRCIMVTPDGNFHRGYHLQVLGKEHHILRYFTSPDL

Target ORF information:

RefSeq Version	NM_138939.2
Organism	Homo sapiens(human)
Definition	Homo sapiens CD200 receptor 1 (CD200R1), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_138939.2

ORF Insert Sequence:

ATGCTCTGCC CTTGGAGAAC TGCTAACCTA GGGCTACTGT TGATTTTGAC TATCTTCTTA 
GTGGCCGAAG CGGAGGGTGC TGCTCAACCA AACAACTCAT TAATGCTGCA AACTAGCAAG 
GAGAATCATG CTTTAGCTTC AAGCAGTTTA TGTATGGATG AAAAACAGAT TACACAGAAC 
TACTCGAAAG TACTCGCAGA AGTTAACACT TCATGGCCTG TAAAGATGGC TACAAATGCT 
GTGCTTTGTT GCCCTCCTAT CGCATTAAGA AATTTGATCA TAATAACATG GGAAATAATC 
CTGAGAGGCC AGCCTTCCTG CACAAAAGCC TACAAGAAAG AAACAAATGA GACCAAGGAA 
ACCAACTGTA CTGATGAGAG AATAACCTGG GTCTCCAGAC CTGATCAGAA TTCGGACCTT 
CAGATTCGTA CCGTGGCCAT CACTCATGAC GGGTATTACA GATGCATAAT GGTAACACCT 
GATGGGAATT TCCATCGTGG ATATCACCTC CAAGTGTTAG GTAAGGAGCA TCATATATTG 
AGGTATTTCA CATCACCAGA TTTGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

CD200R1 ( NM_138939.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_620385.1 Homo sapiens CD200 receptor 1 (CD200R1), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu23772
Clone ID Related Accession (Same CDS sequence)	NM_138939.2 , NM_138939.3
Accession Version	NM_138939.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 567bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2020-01-03
Organism	Homo sapiens(human)
Product	cell surface glycoprotein CD200 receptor 1 isoform b precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AC074044.8, AK126349.1 and AF497549.1. On May 31, 2019 this sequence version replaced NM_138939.2. Transcript Variant: This variant (2) includes an alternate exon in the coding region, compared to variant 1. This results in a frameshift and early stop codon, as well as loss of an immunoglobulin and transmembrane domain in the protein (isoform b), compared to isoform a. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AF497549.1, DB219948.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END##

ATGCTCTGCC CTTGGAGAAC TGCTAACCTA GGGCTACTGT TGATTTTGAC TATCTTCTTA 
GTGGCCGAAG CGGAGGGTGC TGCTCAACCA AACAACTCAT TAATGCTGCA AACTAGCAAG 
GAGAATCATG CTTTAGCTTC AAGCAGTTTA TGTATGGATG AAAAACAGAT TACACAGAAC 
TACTCGAAAG TACTCGCAGA AGTTAACACT TCATGGCCTG TAAAGATGGC TACAAATGCT 
GTGCTTTGTT GCCCTCCTAT CGCATTAAGA AATTTGATCA TAATAACATG GGAAATAATC 
CTGAGAGGCC AGCCTTCCTG CACAAAAGCC TACAAGAAAG AAACAAATGA GACCAAGGAA 
ACCAACTGTA CTGATGAGAG AATAACCTGG GTCTCCAGAC CTGATCAGAA TTCGGACCTT 
CAGATTCGTA CCGTGGCCAT CACTCATGAC GGGTATTACA GATGCATAAT GGTAACACCT 
GATGGGAATT TCCATCGTGG ATATCACCTC CAAGTGTTAG GTAAGGAGCA TCATATATTG 
AGGTATTTCA CATCACCAGA TTTGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_620385.1
CDS	247..813
Translation	MLCPWRTANLGLLLILTIFLVAEAEGAAQPNNSLMLQTSKENHALASSSLCMDEKQITQNYSKVLAEVNTSWPVKMATNAVLCCPPIALRNLIIITWEIILRGQPSCTKAYKKETNETKETNCTDERITWVSRPDQNSDLQIRTVAITHDGYYRCIMVTPDGNFHRGYHLQVLGKEHHILRYFTSPDL

Target ORF information:

RefSeq Version	NM_138939.3
Organism	Homo sapiens(human)
Definition	Homo sapiens CD200 receptor 1 (CD200R1), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_138939.3

ORF Insert Sequence:

ATGCTCTGCC CTTGGAGAAC TGCTAACCTA GGGCTACTGT TGATTTTGAC TATCTTCTTA 
GTGGCCGAAG CGGAGGGTGC TGCTCAACCA AACAACTCAT TAATGCTGCA AACTAGCAAG 
GAGAATCATG CTTTAGCTTC AAGCAGTTTA TGTATGGATG AAAAACAGAT TACACAGAAC 
TACTCGAAAG TACTCGCAGA AGTTAACACT TCATGGCCTG TAAAGATGGC TACAAATGCT 
GTGCTTTGTT GCCCTCCTAT CGCATTAAGA AATTTGATCA TAATAACATG GGAAATAATC 
CTGAGAGGCC AGCCTTCCTG CACAAAAGCC TACAAGAAAG AAACAAATGA GACCAAGGAA 
ACCAACTGTA CTGATGAGAG AATAACCTGG GTCTCCAGAC CTGATCAGAA TTCGGACCTT 
CAGATTCGTA CCGTGGCCAT CACTCATGAC GGGTATTACA GATGCATAAT GGTAACACCT 
GATGGGAATT TCCATCGTGG ATATCACCTC CAAGTGTTAG GTAAGGAGCA TCATATATTG 
AGGTATTTCA CATCACCAGA TTTGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Gingival Tissue Inflammation Promotes Increased Matrix Metalloproteinase-12 Production by CD200R
Journal of immunology (Baltimore, Md. : 1950)199(12)4023-4035(2017 Dec)
Bj?rnfot Holmstr?m S,Clark R,Zwicker S,Bureik D,Kvedaraite E,Bernasconi E,Nguyen Hoang AT,Johannsen G,Marsland BJ,Bostr?m EA,Svensson M

A CD200R-CD28 fusion protein appropriates an inhibitory signal to enhance T-cell function and therapy of murine leukemia.
Blood130(22)2410-2419(2017 11)
Oda SK,Daman AW,Garcia NM,Wagener F,Schmitt TM,Tan X,Chapuis AG,Greenberg PD

Changes in expression of the CD200 tolerance-signaling molecule and its receptor (CD200R) by villus trophoblasts during first trimester missed abortion and in chronic histiocytic intervillositis.
American journal of reproductive immunology (New York, N.Y. : 1989)78(1)(2017 Jul)
Clark DA,Dmetrichuk JM,McCready E,Dhesy-Thind S,Arredondo JL

The immunoglobulin superfamily member CD200R identifies cells involved in type 2 immune responses.
Allergy72(7)1081-1090(2017 Jul)
Blom LH,Martel BC,Larsen LF,Hansen CV,Christensen MP,Juel-Berg N,Litman T,Poulsen LK

Reduced expression of monocyte CD200R is associated with enhanced proinflammatory cytokine production in sarcoidosis.
Scientific reports638689(2016 Dec)
Fraser SD,Sadofsky LR,Kaye PM,Hart SP

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CD200R1 cDNA ORF clone, Homo sapiens(human)

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