COMT gene cDNA ORF clone, Homo sapiens(human)

mRNA	Protein	Name
XM_017028594.1	XP_016884083.1	catechol O-methyltransferase isoform X2
NM_001135162.1	NP_001128634.1	catechol O-methyltransferase isoform MB-COMT
NM_001135162.2	NP_001128634.1	catechol O-methyltransferase isoform MB-COMT
NM_007310.3	NP_009294.1	catechol O-methyltransferase isoform S-COMT
NM_001135161.1	NP_001128633.1	catechol O-methyltransferase isoform MB-COMT
NM_001135161.2	NP_001128633.1	catechol O-methyltransferase isoform MB-COMT
XM_011529886.2	XP_011528188.2	catechol O-methyltransferase isoform X1
NM_000754.4	NP_000745.1	catechol O-methyltransferase isoform MB-COMT
NM_000754.3	NP_000745.1	catechol O-methyltransferase isoform MB-COMT
XM_011529886.1	XP_011528188.1	catechol O-methyltransferase isoform X1
NM_007310.2	NP_009294.1	catechol O-methyltransferase isoform S-COMT
NM_001362828.1	NP_001349757.1	catechol O-methyltransferase isoform MB-COMT
NM_001362828.2	NP_001349757.1	catechol O-methyltransferase isoform MB-COMT
XM_017028595.1	XP_016884084.1	catechol O-methyltransferase isoform X2

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu23500	NM_007310.3 Latest version!	Homo sapiens catechol-O-methyltransferase (COMT), transcript variant 4, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
OHu23722	NM_001135161.2 Latest version!	Homo sapiens catechol-O-methyltransferase (COMT), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$216.30 $309.00
OHu23722	NM_001362828.2 Latest version!	Homo sapiens catechol-O-methyltransferase (COMT), transcript variant 5, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$216.30 $309.00
OHu23722	NM_001135162.2 Latest version!	Homo sapiens catechol-O-methyltransferase (COMT), transcript variant 3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$216.30 $309.00
OHu23722	XM_017028595.1 Latest version!	Homo sapiens catechol-O-methyltransferase (COMT), transcript variant X3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$216.30 $309.00
OHu23722	XM_017028594.1 Latest version!	Homo sapiens catechol-O-methyltransferase (COMT), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$216.30 $309.00
OHu57041	XM_011529886.1 Latest version!	Homo sapiens catechol-O-methyltransferase (COMT), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$139.30 $199.00
OHu23722	NM_000754.4 Latest version!	Homo sapiens catechol-O-methyltransferase (COMT), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$139.30 $199.00
OHu105217	XM_011529886.2 Latest version!	Homo sapiens catechol-O-methyltransferase (COMT), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$223.30 $319.00
View Old Accession Versions >>
OHu23722	NM_001135162.1	Homo sapiens catechol-O-methyltransferase (COMT), transcript variant 3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$216.30 $309.00
OHu23722	NM_001135161.1	Homo sapiens catechol-O-methyltransferase (COMT), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$216.30 $309.00
OHu23722	NM_000754.3	Homo sapiens catechol-O-methyltransferase (COMT), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$99.50-$139.30 $199.00
OHu23500	NM_007310.2	Homo sapiens catechol-O-methyltransferase (COMT), transcript variant 4, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
OHu23722	NM_001362828.1	Homo sapiens catechol-O-methyltransferase (COMT), transcript variant 5, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$216.30 $309.00
Hide Old Accession Versions >>

COMT ( NM_007310.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_009294.1 Homo sapiens catechol-O-methyltransferase (COMT), transcript variant 4, mRNA.

Price & Availability↑

CloneID	OHu23500
Clone ID Related Accession (Same CDS sequence)	NM_007310.3 , NM_007310.2
Accession Version	NM_007310.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 666bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2020-01-04
Organism	Homo sapiens(human)
Product	catechol O-methyltransferase isoform S-COMT
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AK290440.1 and AC005663.2. On Jun 2, 2019 this sequence version replaced NM_007310.2. Transcript Variant: This variant (4, also known as S-COMT) contains a shorter 5' UTR and a translation start site which lies 50 codons downstream compared to that of variant 1. The resulting isoform (S-COMT) is shorter at the N-terminus compared to isoform MB-COMT. S-COMT is a soluble protein. Sequence Note: This RefSeq record was created from transcript and genomic sequence data because no single transcript was available for the full length of the gene. The extent of this transcript is supported by transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR7346977.674721.1, SRR1803612.88486.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: full length.

ATGGGTGACA CCAAGGAGCA GCGCATCCTG AACCACGTGC TGCAGCATGC GGAGCCCGGG 
AACGCACAGA GCGTGCTGGA GGCCATTGAC ACCTACTGCG AGCAGAAGGA GTGGGCCATG 
AACGTGGGCG ACAAGAAAGG CAAGATCGTG GACGCCGTGA TTCAGGAGCA CCAGCCCTCC 
GTGCTGCTGG AGCTGGGGGC CTACTGTGGC TACTCAGCTG TGCGCATGGC CCGCCTGCTG 
TCACCAGGGG CGAGGCTCAT CACCATCGAG ATCAACCCCG ACTGTGCCGC CATCACCCAG 
CGGATGGTGG ATTTCGCTGG CGTGAAGGAC AAGGTCACCC TTGTGGTTGG AGCGTCCCAG 
GACATCATCC CCCAGCTGAA GAAGAAGTAT GATGTGGACA CACTGGACAT GGTCTTCCTC 
GACCACTGGA AGGACCGGTA CCTGCCGGAC ACGCTTCTCT TGGAGGAATG TGGCCTGCTG 
CGGAAGGGGA CAGTGCTACT GGCTGACAAC GTGATCTGCC CAGGTGCGCC AGACTTCCTA 
GCACACGTGC GCGGGAGCAG CTGCTTTGAG TGCACACACT ACCAATCGTT CCTGGAATAC 
AGGGAGGTGG TGGACGGCCT GGAGAAGGCC ATCTACAAGG GCCCAGGCAG CGAAGCAGGG 
CCCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_009294.1
CDS	125..790
Translation	MGDTKEQRILNHVLQHAEPGNAQSVLEAIDTYCEQKEWAMNVGDKKGKIVDAVIQEHQPSVLLELGAYCGYSAVRMARLLSPGARLITIEINPDCAAITQRMVDFAGVKDKVTLVVGASQDIIPQLKKKYDVDTLDMVFLDHWKDRYLPDTLLLEECGLLRKGTVLLADNVICPGAPDFLAHVRGSSCFECTHYQSFLEYREVVDGLEKAIYKGPGSEAGP

Target ORF information:

RefSeq Version	NM_007310.3
Organism	Homo sapiens(human)
Definition	Homo sapiens catechol-O-methyltransferase (COMT), transcript variant 4, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_007310.3

ORF Insert Sequence:

ATGGGTGACA CCAAGGAGCA GCGCATCCTG AACCACGTGC TGCAGCATGC GGAGCCCGGG 
AACGCACAGA GCGTGCTGGA GGCCATTGAC ACCTACTGCG AGCAGAAGGA GTGGGCCATG 
AACGTGGGCG ACAAGAAAGG CAAGATCGTG GACGCCGTGA TTCAGGAGCA CCAGCCCTCC 
GTGCTGCTGG AGCTGGGGGC CTACTGTGGC TACTCAGCTG TGCGCATGGC CCGCCTGCTG 
TCACCAGGGG CGAGGCTCAT CACCATCGAG ATCAACCCCG ACTGTGCCGC CATCACCCAG 
CGGATGGTGG ATTTCGCTGG CGTGAAGGAC AAGGTCACCC TTGTGGTTGG AGCGTCCCAG 
GACATCATCC CCCAGCTGAA GAAGAAGTAT GATGTGGACA CACTGGACAT GGTCTTCCTC 
GACCACTGGA AGGACCGGTA CCTGCCGGAC ACGCTTCTCT TGGAGGAATG TGGCCTGCTG 
CGGAAGGGGA CAGTGCTACT GGCTGACAAC GTGATCTGCC CAGGTGCGCC AGACTTCCTA 
GCACACGTGC GCGGGAGCAG CTGCTTTGAG TGCACACACT ACCAATCGTT CCTGGAATAC 
AGGGAGGTGG TGGACGGCCT GGAGAAGGCC ATCTACAAGG GCCCAGGCAG CGAAGCAGGG 
CCCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

COMT ( NM_007310.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_009294.1 Homo sapiens catechol-O-methyltransferase (COMT), transcript variant 4, mRNA.

Price & Availability↑

CloneID	OHu23500
Clone ID Related Accession (Same CDS sequence)	NM_007310.3 , NM_007310.2
Accession Version	NM_007310.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 666bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-03-03
Organism	Homo sapiens(human)
Product	catechol O-methyltransferase isoform S-COMT
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AK290440.1 and AC005663.2. On Sep 23, 2008 this sequence version replaced NM_007310.1. Transcript Variant: This variant (4, also known as S-COMT) contains a shorter 5' UTR and a translation start site which lies 50 codons downstream compared to that of variant 1. The resulting isoform (S-COMT) is shorter at the N-terminus compared to isoform MB-COMT. S-COMT is a soluble protein. Sequence Note: This RefSeq record was created from transcript and genomic sequence data because no single transcript was available for the full length of the gene. The extent of this transcript is supported by transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1803612.88486.1, SRR1803615.197395.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: full length.

ATGGGTGACA CCAAGGAGCA GCGCATCCTG AACCACGTGC TGCAGCATGC GGAGCCCGGG 
AACGCACAGA GCGTGCTGGA GGCCATTGAC ACCTACTGCG AGCAGAAGGA GTGGGCCATG 
AACGTGGGCG ACAAGAAAGG CAAGATCGTG GACGCCGTGA TTCAGGAGCA CCAGCCCTCC 
GTGCTGCTGG AGCTGGGGGC CTACTGTGGC TACTCAGCTG TGCGCATGGC CCGCCTGCTG 
TCACCAGGGG CGAGGCTCAT CACCATCGAG ATCAACCCCG ACTGTGCCGC CATCACCCAG 
CGGATGGTGG ATTTCGCTGG CGTGAAGGAC AAGGTCACCC TTGTGGTTGG AGCGTCCCAG 
GACATCATCC CCCAGCTGAA GAAGAAGTAT GATGTGGACA CACTGGACAT GGTCTTCCTC 
GACCACTGGA AGGACCGGTA CCTGCCGGAC ACGCTTCTCT TGGAGGAATG TGGCCTGCTG 
CGGAAGGGGA CAGTGCTACT GGCTGACAAC GTGATCTGCC CAGGTGCGCC AGACTTCCTA 
GCACACGTGC GCGGGAGCAG CTGCTTTGAG TGCACACACT ACCAATCGTT CCTGGAATAC 
AGGGAGGTGG TGGACGGCCT GGAGAAGGCC ATCTACAAGG GCCCAGGCAG CGAAGCAGGG 
CCCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_009294.1
CDS	131..796
Translation	MGDTKEQRILNHVLQHAEPGNAQSVLEAIDTYCEQKEWAMNVGDKKGKIVDAVIQEHQPSVLLELGAYCGYSAVRMARLLSPGARLITIEINPDCAAITQRMVDFAGVKDKVTLVVGASQDIIPQLKKKYDVDTLDMVFLDHWKDRYLPDTLLLEECGLLRKGTVLLADNVICPGAPDFLAHVRGSSCFECTHYQSFLEYREVVDGLEKAIYKGPGSEAGP

Target ORF information:

RefSeq Version	NM_007310.2
Organism	Homo sapiens(human)
Definition	Homo sapiens catechol-O-methyltransferase (COMT), transcript variant 4, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_007310.2

ORF Insert Sequence:

ATGGGTGACA CCAAGGAGCA GCGCATCCTG AACCACGTGC TGCAGCATGC GGAGCCCGGG 
AACGCACAGA GCGTGCTGGA GGCCATTGAC ACCTACTGCG AGCAGAAGGA GTGGGCCATG 
AACGTGGGCG ACAAGAAAGG CAAGATCGTG GACGCCGTGA TTCAGGAGCA CCAGCCCTCC 
GTGCTGCTGG AGCTGGGGGC CTACTGTGGC TACTCAGCTG TGCGCATGGC CCGCCTGCTG 
TCACCAGGGG CGAGGCTCAT CACCATCGAG ATCAACCCCG ACTGTGCCGC CATCACCCAG 
CGGATGGTGG ATTTCGCTGG CGTGAAGGAC AAGGTCACCC TTGTGGTTGG AGCGTCCCAG 
GACATCATCC CCCAGCTGAA GAAGAAGTAT GATGTGGACA CACTGGACAT GGTCTTCCTC 
GACCACTGGA AGGACCGGTA CCTGCCGGAC ACGCTTCTCT TGGAGGAATG TGGCCTGCTG 
CGGAAGGGGA CAGTGCTACT GGCTGACAAC GTGATCTGCC CAGGTGCGCC AGACTTCCTA 
GCACACGTGC GCGGGAGCAG CTGCTTTGAG TGCACACACT ACCAATCGTT CCTGGAATAC 
AGGGAGGTGG TGGACGGCCT GGAGAAGGCC ATCTACAAGG GCCCAGGCAG CGAAGCAGGG 
CCCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

COMT ( NM_000754.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_000745.1 Homo sapiens catechol-O-methyltransferase (COMT), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu23722
Clone ID Related Accession (Same CDS sequence)	XM_017028594.1 , NM_001135162.1 , NM_001135162.2 , NM_001135161.1 , NM_001135161.2 , NM_000754.4 , NM_000754.3 , NM_001362828.1 , NM_001362828.2 , XM_017028595.1
Accession Version	NM_000754.3	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 816bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-07-01
Organism	Homo sapiens(human)
Product	catechol O-methyltransferase isoform MB-COMT
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BX461394.2, AK290440.1 and AC005663.2. This sequence is a reference standard in the RefSeqGene project. On Sep 23, 2008 this sequence version replaced NM_000754.2. Transcript Variant: This variant (1, also known as MB-COMT) represents the predominant transcript and encodes the longer isoform (MB-COMT). Variants 1, 2, 3, and 5 all encode isoform MB-COMT and may also make the shorter isoform S-COMT at a low level. MB-COMT is a membrane-bound protein. Sequence Note: This RefSeq record was created from transcript and genomic sequence data because no single transcript was available for the full length of the gene. The extent of this transcript is supported by transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1803613.9530.1, SRR1803614.30643.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## RefSeq Select criteria :: based on conservation, expression, longest protein ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGCCGGAGG CCCCGCCTCT GCTGTTGGCA GCTGTGTTGC TGGGCCTGGT GCTGCTGGTG 
GTGCTGCTGC TGCTTCTGAG GCACTGGGGC TGGGGCCTGT GCCTTATCGG CTGGAACGAG 
TTCATCCTGC AGCCCATCCA CAACCTGCTC ATGGGTGACA CCAAGGAGCA GCGCATCCTG 
AACCACGTGC TGCAGCATGC GGAGCCCGGG AACGCACAGA GCGTGCTGGA GGCCATTGAC 
ACCTACTGCG AGCAGAAGGA GTGGGCCATG AACGTGGGCG ACAAGAAAGG CAAGATCGTG 
GACGCCGTGA TTCAGGAGCA CCAGCCCTCC GTGCTGCTGG AGCTGGGGGC CTACTGTGGC 
TACTCAGCTG TGCGCATGGC CCGCCTGCTG TCACCAGGGG CGAGGCTCAT CACCATCGAG 
ATCAACCCCG ACTGTGCCGC CATCACCCAG CGGATGGTGG ATTTCGCTGG CGTGAAGGAC 
AAGGTCACCC TTGTGGTTGG AGCGTCCCAG GACATCATCC CCCAGCTGAA GAAGAAGTAT 
GATGTGGACA CACTGGACAT GGTCTTCCTC GACCACTGGA AGGACCGGTA CCTGCCGGAC 
ACGCTTCTCT TGGAGGAATG TGGCCTGCTG CGGAAGGGGA CAGTGCTACT GGCTGACAAC 
GTGATCTGCC CAGGTGCGCC AGACTTCCTA GCACACGTGC GCGGGAGCAG CTGCTTTGAG 
TGCACACACT ACCAATCGTT CCTGGAATAC AGGGAGGTGG TGGACGGCCT GGAGAAGGCC 
ATCTACAAGG GCCCAGGCAG CGAAGCAGGG CCCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_000745.1
CDS	250..1065
Translation	MPEAPPLLLAAVLLGLVLLVVLLLLLRHWGWGLCLIGWNEFILQPIHNLLMGDTKEQRILNHVLQHAEPGNAQSVLEAIDTYCEQKEWAMNVGDKKGKIVDAVIQEHQPSVLLELGAYCGYSAVRMARLLSPGARLITIEINPDCAAITQRMVDFAGVKDKVTLVVGASQDIIPQLKKKYDVDTLDMVFLDHWKDRYLPDTLLLEECGLLRKGTVLLADNVICPGAPDFLAHVRGSSCFECTHYQSFLEYREVVDGLEKAIYKGPGSEAGP

Target ORF information:

RefSeq Version	NM_000754.3
Organism	Homo sapiens(human)
Definition	Homo sapiens catechol-O-methyltransferase (COMT), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_000754.3

ORF Insert Sequence:

ATGCCGGAGG CCCCGCCTCT GCTGTTGGCA GCTGTGTTGC TGGGCCTGGT GCTGCTGGTG 
GTGCTGCTGC TGCTTCTGAG GCACTGGGGC TGGGGCCTGT GCCTTATCGG CTGGAACGAG 
TTCATCCTGC AGCCCATCCA CAACCTGCTC ATGGGTGACA CCAAGGAGCA GCGCATCCTG 
AACCACGTGC TGCAGCATGC GGAGCCCGGG AACGCACAGA GCGTGCTGGA GGCCATTGAC 
ACCTACTGCG AGCAGAAGGA GTGGGCCATG AACGTGGGCG ACAAGAAAGG CAAGATCGTG 
GACGCCGTGA TTCAGGAGCA CCAGCCCTCC GTGCTGCTGG AGCTGGGGGC CTACTGTGGC 
TACTCAGCTG TGCGCATGGC CCGCCTGCTG TCACCAGGGG CGAGGCTCAT CACCATCGAG 
ATCAACCCCG ACTGTGCCGC CATCACCCAG CGGATGGTGG ATTTCGCTGG CGTGAAGGAC 
AAGGTCACCC TTGTGGTTGG AGCGTCCCAG GACATCATCC CCCAGCTGAA GAAGAAGTAT 
GATGTGGACA CACTGGACAT GGTCTTCCTC GACCACTGGA AGGACCGGTA CCTGCCGGAC 
ACGCTTCTCT TGGAGGAATG TGGCCTGCTG CGGAAGGGGA CAGTGCTACT GGCTGACAAC 
GTGATCTGCC CAGGTGCGCC AGACTTCCTA GCACACGTGC GCGGGAGCAG CTGCTTTGAG 
TGCACACACT ACCAATCGTT CCTGGAATAC AGGGAGGTGG TGGACGGCCT GGAGAAGGCC 
ATCTACAAGG GCCCAGGCAG CGAAGCAGGG CCCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

COMT ( NM_001135162.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001128634.1 Homo sapiens catechol-O-methyltransferase (COMT), transcript variant 3, mRNA.

Price & Availability↑

CloneID	OHu23722
Clone ID Related Accession (Same CDS sequence)	XM_017028594.1 , NM_001135162.1 , NM_001135162.2 , NM_001135161.1 , NM_001135161.2 , NM_000754.4 , NM_000754.3 , NM_001362828.1 , NM_001362828.2 , XM_017028595.1
Accession Version	NM_001135162.1	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 816bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-03-03
Organism	Homo sapiens(human)
Product	catechol O-methyltransferase isoform MB-COMT
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BE728779.1, AK290440.1 and AC005663.2. Transcript Variant: This variant (3) differs in the 5' UTR compared to variant 1. Variants 1, 2, 3, and 5 all encode isoform MB-COMT and may also make the shorter isoform S-COMT at a low level. MB-COMT is a membrane-bound protein. Sequence Note: This RefSeq record was created from transcript and genomic sequence data because no single transcript was available for the full length of the gene. The extent of this transcript is supported by transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: ERR279852.934.1, BE410186.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968968, SAMEA2142586 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGCCGGAGG CCCCGCCTCT GCTGTTGGCA GCTGTGTTGC TGGGCCTGGT GCTGCTGGTG 
GTGCTGCTGC TGCTTCTGAG GCACTGGGGC TGGGGCCTGT GCCTTATCGG CTGGAACGAG 
TTCATCCTGC AGCCCATCCA CAACCTGCTC ATGGGTGACA CCAAGGAGCA GCGCATCCTG 
AACCACGTGC TGCAGCATGC GGAGCCCGGG AACGCACAGA GCGTGCTGGA GGCCATTGAC 
ACCTACTGCG AGCAGAAGGA GTGGGCCATG AACGTGGGCG ACAAGAAAGG CAAGATCGTG 
GACGCCGTGA TTCAGGAGCA CCAGCCCTCC GTGCTGCTGG AGCTGGGGGC CTACTGTGGC 
TACTCAGCTG TGCGCATGGC CCGCCTGCTG TCACCAGGGG CGAGGCTCAT CACCATCGAG 
ATCAACCCCG ACTGTGCCGC CATCACCCAG CGGATGGTGG ATTTCGCTGG CGTGAAGGAC 
AAGGTCACCC TTGTGGTTGG AGCGTCCCAG GACATCATCC CCCAGCTGAA GAAGAAGTAT 
GATGTGGACA CACTGGACAT GGTCTTCCTC GACCACTGGA AGGACCGGTA CCTGCCGGAC 
ACGCTTCTCT TGGAGGAATG TGGCCTGCTG CGGAAGGGGA CAGTGCTACT GGCTGACAAC 
GTGATCTGCC CAGGTGCGCC AGACTTCCTA GCACACGTGC GCGGGAGCAG CTGCTTTGAG 
TGCACACACT ACCAATCGTT CCTGGAATAC AGGGAGGTGG TGGACGGCCT GGAGAAGGCC 
ATCTACAAGG GCCCAGGCAG CGAAGCAGGG CCCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001128634.1
CDS	225..1040
Translation	MPEAPPLLLAAVLLGLVLLVVLLLLLRHWGWGLCLIGWNEFILQPIHNLLMGDTKEQRILNHVLQHAEPGNAQSVLEAIDTYCEQKEWAMNVGDKKGKIVDAVIQEHQPSVLLELGAYCGYSAVRMARLLSPGARLITIEINPDCAAITQRMVDFAGVKDKVTLVVGASQDIIPQLKKKYDVDTLDMVFLDHWKDRYLPDTLLLEECGLLRKGTVLLADNVICPGAPDFLAHVRGSSCFECTHYQSFLEYREVVDGLEKAIYKGPGSEAGP

Target ORF information:

RefSeq Version	NM_001135162.1
Organism	Homo sapiens(human)
Definition	Homo sapiens catechol-O-methyltransferase (COMT), transcript variant 3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001135162.1

ORF Insert Sequence:

ATGCCGGAGG CCCCGCCTCT GCTGTTGGCA GCTGTGTTGC TGGGCCTGGT GCTGCTGGTG 
GTGCTGCTGC TGCTTCTGAG GCACTGGGGC TGGGGCCTGT GCCTTATCGG CTGGAACGAG 
TTCATCCTGC AGCCCATCCA CAACCTGCTC ATGGGTGACA CCAAGGAGCA GCGCATCCTG 
AACCACGTGC TGCAGCATGC GGAGCCCGGG AACGCACAGA GCGTGCTGGA GGCCATTGAC 
ACCTACTGCG AGCAGAAGGA GTGGGCCATG AACGTGGGCG ACAAGAAAGG CAAGATCGTG 
GACGCCGTGA TTCAGGAGCA CCAGCCCTCC GTGCTGCTGG AGCTGGGGGC CTACTGTGGC 
TACTCAGCTG TGCGCATGGC CCGCCTGCTG TCACCAGGGG CGAGGCTCAT CACCATCGAG 
ATCAACCCCG ACTGTGCCGC CATCACCCAG CGGATGGTGG ATTTCGCTGG CGTGAAGGAC 
AAGGTCACCC TTGTGGTTGG AGCGTCCCAG GACATCATCC CCCAGCTGAA GAAGAAGTAT 
GATGTGGACA CACTGGACAT GGTCTTCCTC GACCACTGGA AGGACCGGTA CCTGCCGGAC 
ACGCTTCTCT TGGAGGAATG TGGCCTGCTG CGGAAGGGGA CAGTGCTACT GGCTGACAAC 
GTGATCTGCC CAGGTGCGCC AGACTTCCTA GCACACGTGC GCGGGAGCAG CTGCTTTGAG 
TGCACACACT ACCAATCGTT CCTGGAATAC AGGGAGGTGG TGGACGGCCT GGAGAAGGCC 
ATCTACAAGG GCCCAGGCAG CGAAGCAGGG CCCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

COMT ( NM_001135162.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_001128634.1 Homo sapiens catechol-O-methyltransferase (COMT), transcript variant 3, mRNA.

Price & Availability↑

CloneID	OHu23722
Clone ID Related Accession (Same CDS sequence)	XM_017028594.1 , NM_001135162.1 , NM_001135162.2 , NM_001135161.1 , NM_001135161.2 , NM_000754.4 , NM_000754.3 , NM_001362828.1 , NM_001362828.2 , XM_017028595.1
Accession Version	NM_001135162.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 816bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2020-01-03
Organism	Homo sapiens(human)
Product	catechol O-methyltransferase isoform MB-COMT
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AC005663.2, BE728779.1 and AK290440.1. On Jun 2, 2019 this sequence version replaced NM_001135162.1. Transcript Variant: This variant (3) differs in the 5' UTR compared to variant 1. Variants 1, 2, 3, and 5 all encode isoform MB-COMT and may also make the shorter isoform S-COMT at a low level. MB-COMT is a membrane-bound protein. Sequence Note: This RefSeq record was created from transcript and genomic sequence data because no single transcript was available for the full length of the gene. The extent of this transcript is supported by transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC100018.2, SRR5189652.6618.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968968, SAMEA2142586 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGCCGGAGG CCCCGCCTCT GCTGTTGGCA GCTGTGTTGC TGGGCCTGGT GCTGCTGGTG 
GTGCTGCTGC TGCTTCTGAG GCACTGGGGC TGGGGCCTGT GCCTTATCGG CTGGAACGAG 
TTCATCCTGC AGCCCATCCA CAACCTGCTC ATGGGTGACA CCAAGGAGCA GCGCATCCTG 
AACCACGTGC TGCAGCATGC GGAGCCCGGG AACGCACAGA GCGTGCTGGA GGCCATTGAC 
ACCTACTGCG AGCAGAAGGA GTGGGCCATG AACGTGGGCG ACAAGAAAGG CAAGATCGTG 
GACGCCGTGA TTCAGGAGCA CCAGCCCTCC GTGCTGCTGG AGCTGGGGGC CTACTGTGGC 
TACTCAGCTG TGCGCATGGC CCGCCTGCTG TCACCAGGGG CGAGGCTCAT CACCATCGAG 
ATCAACCCCG ACTGTGCCGC CATCACCCAG CGGATGGTGG ATTTCGCTGG CGTGAAGGAC 
AAGGTCACCC TTGTGGTTGG AGCGTCCCAG GACATCATCC CCCAGCTGAA GAAGAAGTAT 
GATGTGGACA CACTGGACAT GGTCTTCCTC GACCACTGGA AGGACCGGTA CCTGCCGGAC 
ACGCTTCTCT TGGAGGAATG TGGCCTGCTG CGGAAGGGGA CAGTGCTACT GGCTGACAAC 
GTGATCTGCC CAGGTGCGCC AGACTTCCTA GCACACGTGC GCGGGAGCAG CTGCTTTGAG 
TGCACACACT ACCAATCGTT CCTGGAATAC AGGGAGGTGG TGGACGGCCT GGAGAAGGCC 
ATCTACAAGG GCCCAGGCAG CGAAGCAGGG CCCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001128634.1
CDS	229..1044
Translation	MPEAPPLLLAAVLLGLVLLVVLLLLLRHWGWGLCLIGWNEFILQPIHNLLMGDTKEQRILNHVLQHAEPGNAQSVLEAIDTYCEQKEWAMNVGDKKGKIVDAVIQEHQPSVLLELGAYCGYSAVRMARLLSPGARLITIEINPDCAAITQRMVDFAGVKDKVTLVVGASQDIIPQLKKKYDVDTLDMVFLDHWKDRYLPDTLLLEECGLLRKGTVLLADNVICPGAPDFLAHVRGSSCFECTHYQSFLEYREVVDGLEKAIYKGPGSEAGP

Target ORF information:

RefSeq Version	NM_001135162.2
Organism	Homo sapiens(human)
Definition	Homo sapiens catechol-O-methyltransferase (COMT), transcript variant 3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001135162.2

ORF Insert Sequence:

ATGCCGGAGG CCCCGCCTCT GCTGTTGGCA GCTGTGTTGC TGGGCCTGGT GCTGCTGGTG 
GTGCTGCTGC TGCTTCTGAG GCACTGGGGC TGGGGCCTGT GCCTTATCGG CTGGAACGAG 
TTCATCCTGC AGCCCATCCA CAACCTGCTC ATGGGTGACA CCAAGGAGCA GCGCATCCTG 
AACCACGTGC TGCAGCATGC GGAGCCCGGG AACGCACAGA GCGTGCTGGA GGCCATTGAC 
ACCTACTGCG AGCAGAAGGA GTGGGCCATG AACGTGGGCG ACAAGAAAGG CAAGATCGTG 
GACGCCGTGA TTCAGGAGCA CCAGCCCTCC GTGCTGCTGG AGCTGGGGGC CTACTGTGGC 
TACTCAGCTG TGCGCATGGC CCGCCTGCTG TCACCAGGGG CGAGGCTCAT CACCATCGAG 
ATCAACCCCG ACTGTGCCGC CATCACCCAG CGGATGGTGG ATTTCGCTGG CGTGAAGGAC 
AAGGTCACCC TTGTGGTTGG AGCGTCCCAG GACATCATCC CCCAGCTGAA GAAGAAGTAT 
GATGTGGACA CACTGGACAT GGTCTTCCTC GACCACTGGA AGGACCGGTA CCTGCCGGAC 
ACGCTTCTCT TGGAGGAATG TGGCCTGCTG CGGAAGGGGA CAGTGCTACT GGCTGACAAC 
GTGATCTGCC CAGGTGCGCC AGACTTCCTA GCACACGTGC GCGGGAGCAG CTGCTTTGAG 
TGCACACACT ACCAATCGTT CCTGGAATAC AGGGAGGTGG TGGACGGCCT GGAGAAGGCC 
ATCTACAAGG GCCCAGGCAG CGAAGCAGGG CCCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

COMT ( NM_001135161.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001128633.1 Homo sapiens catechol-O-methyltransferase (COMT), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu23722
Clone ID Related Accession (Same CDS sequence)	XM_017028594.1 , NM_001135162.1 , NM_001135162.2 , NM_001135161.1 , NM_001135161.2 , NM_000754.4 , NM_000754.3 , NM_001362828.1 , NM_001362828.2 , XM_017028595.1
Accession Version	NM_001135161.1	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 816bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-03-03
Organism	Homo sapiens(human)
Product	catechol O-methyltransferase isoform MB-COMT
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BE386545.1, AK290440.1 and AC005663.2. Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 1. Variants 1, 2, 3, and 5 all encode isoform MB-COMT and may also make the shorter isoform S-COMT at a low level. MB-COMT is a membrane-bound protein. Sequence Note: This RefSeq record was created from transcript and genomic sequence data because no single transcript was available for the full length of the gene. The extent of this transcript is supported by transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BQ679611.1, BQ890518.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968968, SAMEA2145893 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGCCGGAGG CCCCGCCTCT GCTGTTGGCA GCTGTGTTGC TGGGCCTGGT GCTGCTGGTG 
GTGCTGCTGC TGCTTCTGAG GCACTGGGGC TGGGGCCTGT GCCTTATCGG CTGGAACGAG 
TTCATCCTGC AGCCCATCCA CAACCTGCTC ATGGGTGACA CCAAGGAGCA GCGCATCCTG 
AACCACGTGC TGCAGCATGC GGAGCCCGGG AACGCACAGA GCGTGCTGGA GGCCATTGAC 
ACCTACTGCG AGCAGAAGGA GTGGGCCATG AACGTGGGCG ACAAGAAAGG CAAGATCGTG 
GACGCCGTGA TTCAGGAGCA CCAGCCCTCC GTGCTGCTGG AGCTGGGGGC CTACTGTGGC 
TACTCAGCTG TGCGCATGGC CCGCCTGCTG TCACCAGGGG CGAGGCTCAT CACCATCGAG 
ATCAACCCCG ACTGTGCCGC CATCACCCAG CGGATGGTGG ATTTCGCTGG CGTGAAGGAC 
AAGGTCACCC TTGTGGTTGG AGCGTCCCAG GACATCATCC CCCAGCTGAA GAAGAAGTAT 
GATGTGGACA CACTGGACAT GGTCTTCCTC GACCACTGGA AGGACCGGTA CCTGCCGGAC 
ACGCTTCTCT TGGAGGAATG TGGCCTGCTG CGGAAGGGGA CAGTGCTACT GGCTGACAAC 
GTGATCTGCC CAGGTGCGCC AGACTTCCTA GCACACGTGC GCGGGAGCAG CTGCTTTGAG 
TGCACACACT ACCAATCGTT CCTGGAATAC AGGGAGGTGG TGGACGGCCT GGAGAAGGCC 
ATCTACAAGG GCCCAGGCAG CGAAGCAGGG CCCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001128633.1
CDS	208..1023
Translation	MPEAPPLLLAAVLLGLVLLVVLLLLLRHWGWGLCLIGWNEFILQPIHNLLMGDTKEQRILNHVLQHAEPGNAQSVLEAIDTYCEQKEWAMNVGDKKGKIVDAVIQEHQPSVLLELGAYCGYSAVRMARLLSPGARLITIEINPDCAAITQRMVDFAGVKDKVTLVVGASQDIIPQLKKKYDVDTLDMVFLDHWKDRYLPDTLLLEECGLLRKGTVLLADNVICPGAPDFLAHVRGSSCFECTHYQSFLEYREVVDGLEKAIYKGPGSEAGP

Target ORF information:

RefSeq Version	NM_001135161.1
Organism	Homo sapiens(human)
Definition	Homo sapiens catechol-O-methyltransferase (COMT), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001135161.1

ORF Insert Sequence:

ATGCCGGAGG CCCCGCCTCT GCTGTTGGCA GCTGTGTTGC TGGGCCTGGT GCTGCTGGTG 
GTGCTGCTGC TGCTTCTGAG GCACTGGGGC TGGGGCCTGT GCCTTATCGG CTGGAACGAG 
TTCATCCTGC AGCCCATCCA CAACCTGCTC ATGGGTGACA CCAAGGAGCA GCGCATCCTG 
AACCACGTGC TGCAGCATGC GGAGCCCGGG AACGCACAGA GCGTGCTGGA GGCCATTGAC 
ACCTACTGCG AGCAGAAGGA GTGGGCCATG AACGTGGGCG ACAAGAAAGG CAAGATCGTG 
GACGCCGTGA TTCAGGAGCA CCAGCCCTCC GTGCTGCTGG AGCTGGGGGC CTACTGTGGC 
TACTCAGCTG TGCGCATGGC CCGCCTGCTG TCACCAGGGG CGAGGCTCAT CACCATCGAG 
ATCAACCCCG ACTGTGCCGC CATCACCCAG CGGATGGTGG ATTTCGCTGG CGTGAAGGAC 
AAGGTCACCC TTGTGGTTGG AGCGTCCCAG GACATCATCC CCCAGCTGAA GAAGAAGTAT 
GATGTGGACA CACTGGACAT GGTCTTCCTC GACCACTGGA AGGACCGGTA CCTGCCGGAC 
ACGCTTCTCT TGGAGGAATG TGGCCTGCTG CGGAAGGGGA CAGTGCTACT GGCTGACAAC 
GTGATCTGCC CAGGTGCGCC AGACTTCCTA GCACACGTGC GCGGGAGCAG CTGCTTTGAG 
TGCACACACT ACCAATCGTT CCTGGAATAC AGGGAGGTGG TGGACGGCCT GGAGAAGGCC 
ATCTACAAGG GCCCAGGCAG CGAAGCAGGG CCCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

COMT ( NM_001135161.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_001128633.1 Homo sapiens catechol-O-methyltransferase (COMT), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu23722
Clone ID Related Accession (Same CDS sequence)	XM_017028594.1 , NM_001135162.1 , NM_001135162.2 , NM_001135161.1 , NM_001135161.2 , NM_000754.4 , NM_000754.3 , NM_001362828.1 , NM_001362828.2 , XM_017028595.1
Accession Version	NM_001135161.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 816bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2020-01-03
Organism	Homo sapiens(human)
Product	catechol O-methyltransferase isoform MB-COMT
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AC005663.2, BE386545.1 and AK290440.1. On Jun 2, 2019 this sequence version replaced NM_001135161.1. Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 1. Variants 1, 2, 3, and 5 all encode isoform MB-COMT and may also make the shorter isoform S-COMT at a low level. MB-COMT is a membrane-bound protein. Sequence Note: This RefSeq record was created from transcript and genomic sequence data because no single transcript was available for the full length of the gene. The extent of this transcript is supported by transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR5189667.196544.1, SRR5189667.106454.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968968, SAMEA2145893 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGCCGGAGG CCCCGCCTCT GCTGTTGGCA GCTGTGTTGC TGGGCCTGGT GCTGCTGGTG 
GTGCTGCTGC TGCTTCTGAG GCACTGGGGC TGGGGCCTGT GCCTTATCGG CTGGAACGAG 
TTCATCCTGC AGCCCATCCA CAACCTGCTC ATGGGTGACA CCAAGGAGCA GCGCATCCTG 
AACCACGTGC TGCAGCATGC GGAGCCCGGG AACGCACAGA GCGTGCTGGA GGCCATTGAC 
ACCTACTGCG AGCAGAAGGA GTGGGCCATG AACGTGGGCG ACAAGAAAGG CAAGATCGTG 
GACGCCGTGA TTCAGGAGCA CCAGCCCTCC GTGCTGCTGG AGCTGGGGGC CTACTGTGGC 
TACTCAGCTG TGCGCATGGC CCGCCTGCTG TCACCAGGGG CGAGGCTCAT CACCATCGAG 
ATCAACCCCG ACTGTGCCGC CATCACCCAG CGGATGGTGG ATTTCGCTGG CGTGAAGGAC 
AAGGTCACCC TTGTGGTTGG AGCGTCCCAG GACATCATCC CCCAGCTGAA GAAGAAGTAT 
GATGTGGACA CACTGGACAT GGTCTTCCTC GACCACTGGA AGGACCGGTA CCTGCCGGAC 
ACGCTTCTCT TGGAGGAATG TGGCCTGCTG CGGAAGGGGA CAGTGCTACT GGCTGACAAC 
GTGATCTGCC CAGGTGCGCC AGACTTCCTA GCACACGTGC GCGGGAGCAG CTGCTTTGAG 
TGCACACACT ACCAATCGTT CCTGGAATAC AGGGAGGTGG TGGACGGCCT GGAGAAGGCC 
ATCTACAAGG GCCCAGGCAG CGAAGCAGGG CCCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001128633.1
CDS	243..1058
Translation	MPEAPPLLLAAVLLGLVLLVVLLLLLRHWGWGLCLIGWNEFILQPIHNLLMGDTKEQRILNHVLQHAEPGNAQSVLEAIDTYCEQKEWAMNVGDKKGKIVDAVIQEHQPSVLLELGAYCGYSAVRMARLLSPGARLITIEINPDCAAITQRMVDFAGVKDKVTLVVGASQDIIPQLKKKYDVDTLDMVFLDHWKDRYLPDTLLLEECGLLRKGTVLLADNVICPGAPDFLAHVRGSSCFECTHYQSFLEYREVVDGLEKAIYKGPGSEAGP

Target ORF information:

RefSeq Version	NM_001135161.2
Organism	Homo sapiens(human)
Definition	Homo sapiens catechol-O-methyltransferase (COMT), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001135161.2

ORF Insert Sequence:

ATGCCGGAGG CCCCGCCTCT GCTGTTGGCA GCTGTGTTGC TGGGCCTGGT GCTGCTGGTG 
GTGCTGCTGC TGCTTCTGAG GCACTGGGGC TGGGGCCTGT GCCTTATCGG CTGGAACGAG 
TTCATCCTGC AGCCCATCCA CAACCTGCTC ATGGGTGACA CCAAGGAGCA GCGCATCCTG 
AACCACGTGC TGCAGCATGC GGAGCCCGGG AACGCACAGA GCGTGCTGGA GGCCATTGAC 
ACCTACTGCG AGCAGAAGGA GTGGGCCATG AACGTGGGCG ACAAGAAAGG CAAGATCGTG 
GACGCCGTGA TTCAGGAGCA CCAGCCCTCC GTGCTGCTGG AGCTGGGGGC CTACTGTGGC 
TACTCAGCTG TGCGCATGGC CCGCCTGCTG TCACCAGGGG CGAGGCTCAT CACCATCGAG 
ATCAACCCCG ACTGTGCCGC CATCACCCAG CGGATGGTGG ATTTCGCTGG CGTGAAGGAC 
AAGGTCACCC TTGTGGTTGG AGCGTCCCAG GACATCATCC CCCAGCTGAA GAAGAAGTAT 
GATGTGGACA CACTGGACAT GGTCTTCCTC GACCACTGGA AGGACCGGTA CCTGCCGGAC 
ACGCTTCTCT TGGAGGAATG TGGCCTGCTG CGGAAGGGGA CAGTGCTACT GGCTGACAAC 
GTGATCTGCC CAGGTGCGCC AGACTTCCTA GCACACGTGC GCGGGAGCAG CTGCTTTGAG 
TGCACACACT ACCAATCGTT CCTGGAATAC AGGGAGGTGG TGGACGGCCT GGAGAAGGCC 
ATCTACAAGG GCCCAGGCAG CGAAGCAGGG CCCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

COMT ( NM_001362828.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001349757.1 Homo sapiens catechol-O-methyltransferase (COMT), transcript variant 5, mRNA.

Price & Availability↑

CloneID	OHu23722
Clone ID Related Accession (Same CDS sequence)	XM_017028594.1 , NM_001135162.1 , NM_001135162.2 , NM_001135161.1 , NM_001135161.2 , NM_000754.4 , NM_000754.3 , NM_001362828.1 , NM_001362828.2 , XM_017028595.1
Accession Version	NM_001362828.1	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 816bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-03-03
Organism	Homo sapiens(human)
Product	catechol O-methyltransferase isoform MB-COMT
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AC000090.3 and AC005663.2. On Apr 28, 2018 this sequence version replaced XM_017028594.2. Transcript Variant: This variant (5) differs in the 5' UTR compared to variant 1. Variants 1, 2, 3, and 5 all encode isoform MB-COMT and may also make the shorter isoform S-COMT at a low level. MB-COMT is a membrane-bound protein. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR3476690.394352.1, SRR3476690.1098795.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: full length.

ATGCCGGAGG CCCCGCCTCT GCTGTTGGCA GCTGTGTTGC TGGGCCTGGT GCTGCTGGTG 
GTGCTGCTGC TGCTTCTGAG GCACTGGGGC TGGGGCCTGT GCCTTATCGG CTGGAACGAG 
TTCATCCTGC AGCCCATCCA CAACCTGCTC ATGGGTGACA CCAAGGAGCA GCGCATCCTG 
AACCACGTGC TGCAGCATGC GGAGCCCGGG AACGCACAGA GCGTGCTGGA GGCCATTGAC 
ACCTACTGCG AGCAGAAGGA GTGGGCCATG AACGTGGGCG ACAAGAAAGG CAAGATCGTG 
GACGCCGTGA TTCAGGAGCA CCAGCCCTCC GTGCTGCTGG AGCTGGGGGC CTACTGTGGC 
TACTCAGCTG TGCGCATGGC CCGCCTGCTG TCACCAGGGG CGAGGCTCAT CACCATCGAG 
ATCAACCCCG ACTGTGCCGC CATCACCCAG CGGATGGTGG ATTTCGCTGG CGTGAAGGAC 
AAGGTCACCC TTGTGGTTGG AGCGTCCCAG GACATCATCC CCCAGCTGAA GAAGAAGTAT 
GATGTGGACA CACTGGACAT GGTCTTCCTC GACCACTGGA AGGACCGGTA CCTGCCGGAC 
ACGCTTCTCT TGGAGGAATG TGGCCTGCTG CGGAAGGGGA CAGTGCTACT GGCTGACAAC 
GTGATCTGCC CAGGTGCGCC AGACTTCCTA GCACACGTGC GCGGGAGCAG CTGCTTTGAG 
TGCACACACT ACCAATCGTT CCTGGAATAC AGGGAGGTGG TGGACGGCCT GGAGAAGGCC 
ATCTACAAGG GCCCAGGCAG CGAAGCAGGG CCCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001349757.1
CDS	544..1359
Translation	MPEAPPLLLAAVLLGLVLLVVLLLLLRHWGWGLCLIGWNEFILQPIHNLLMGDTKEQRILNHVLQHAEPGNAQSVLEAIDTYCEQKEWAMNVGDKKGKIVDAVIQEHQPSVLLELGAYCGYSAVRMARLLSPGARLITIEINPDCAAITQRMVDFAGVKDKVTLVVGASQDIIPQLKKKYDVDTLDMVFLDHWKDRYLPDTLLLEECGLLRKGTVLLADNVICPGAPDFLAHVRGSSCFECTHYQSFLEYREVVDGLEKAIYKGPGSEAGP

Target ORF information:

RefSeq Version	NM_001362828.1
Organism	Homo sapiens(human)
Definition	Homo sapiens catechol-O-methyltransferase (COMT), transcript variant 5, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001362828.1

ORF Insert Sequence:

ATGCCGGAGG CCCCGCCTCT GCTGTTGGCA GCTGTGTTGC TGGGCCTGGT GCTGCTGGTG 
GTGCTGCTGC TGCTTCTGAG GCACTGGGGC TGGGGCCTGT GCCTTATCGG CTGGAACGAG 
TTCATCCTGC AGCCCATCCA CAACCTGCTC ATGGGTGACA CCAAGGAGCA GCGCATCCTG 
AACCACGTGC TGCAGCATGC GGAGCCCGGG AACGCACAGA GCGTGCTGGA GGCCATTGAC 
ACCTACTGCG AGCAGAAGGA GTGGGCCATG AACGTGGGCG ACAAGAAAGG CAAGATCGTG 
GACGCCGTGA TTCAGGAGCA CCAGCCCTCC GTGCTGCTGG AGCTGGGGGC CTACTGTGGC 
TACTCAGCTG TGCGCATGGC CCGCCTGCTG TCACCAGGGG CGAGGCTCAT CACCATCGAG 
ATCAACCCCG ACTGTGCCGC CATCACCCAG CGGATGGTGG ATTTCGCTGG CGTGAAGGAC 
AAGGTCACCC TTGTGGTTGG AGCGTCCCAG GACATCATCC CCCAGCTGAA GAAGAAGTAT 
GATGTGGACA CACTGGACAT GGTCTTCCTC GACCACTGGA AGGACCGGTA CCTGCCGGAC 
ACGCTTCTCT TGGAGGAATG TGGCCTGCTG CGGAAGGGGA CAGTGCTACT GGCTGACAAC 
GTGATCTGCC CAGGTGCGCC AGACTTCCTA GCACACGTGC GCGGGAGCAG CTGCTTTGAG 
TGCACACACT ACCAATCGTT CCTGGAATAC AGGGAGGTGG TGGACGGCCT GGAGAAGGCC 
ATCTACAAGG GCCCAGGCAG CGAAGCAGGG CCCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

COMT ( NM_001362828.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_001349757.1 Homo sapiens catechol-O-methyltransferase (COMT), transcript variant 5, mRNA.

Price & Availability↑

CloneID	OHu23722
Clone ID Related Accession (Same CDS sequence)	XM_017028594.1 , NM_001135162.1 , NM_001135162.2 , NM_001135161.1 , NM_001135161.2 , NM_000754.4 , NM_000754.3 , NM_001362828.1 , NM_001362828.2 , XM_017028595.1
Accession Version	NM_001362828.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 816bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2020-01-03
Organism	Homo sapiens(human)
Product	catechol O-methyltransferase isoform MB-COMT
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AC000090.3 and AC005663.2. On Jun 2, 2019 this sequence version replaced NM_001362828.1. Transcript Variant: This variant (5) differs in the 5' UTR compared to variant 1. Variants 1, 2, 3, and 5 all encode isoform MB-COMT and may also make the shorter isoform S-COMT at a low level. MB-COMT is a membrane-bound protein. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR3476690.394352.1, SRR7346977.148071.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: full length.

ATGCCGGAGG CCCCGCCTCT GCTGTTGGCA GCTGTGTTGC TGGGCCTGGT GCTGCTGGTG 
GTGCTGCTGC TGCTTCTGAG GCACTGGGGC TGGGGCCTGT GCCTTATCGG CTGGAACGAG 
TTCATCCTGC AGCCCATCCA CAACCTGCTC ATGGGTGACA CCAAGGAGCA GCGCATCCTG 
AACCACGTGC TGCAGCATGC GGAGCCCGGG AACGCACAGA GCGTGCTGGA GGCCATTGAC 
ACCTACTGCG AGCAGAAGGA GTGGGCCATG AACGTGGGCG ACAAGAAAGG CAAGATCGTG 
GACGCCGTGA TTCAGGAGCA CCAGCCCTCC GTGCTGCTGG AGCTGGGGGC CTACTGTGGC 
TACTCAGCTG TGCGCATGGC CCGCCTGCTG TCACCAGGGG CGAGGCTCAT CACCATCGAG 
ATCAACCCCG ACTGTGCCGC CATCACCCAG CGGATGGTGG ATTTCGCTGG CGTGAAGGAC 
AAGGTCACCC TTGTGGTTGG AGCGTCCCAG GACATCATCC CCCAGCTGAA GAAGAAGTAT 
GATGTGGACA CACTGGACAT GGTCTTCCTC GACCACTGGA AGGACCGGTA CCTGCCGGAC 
ACGCTTCTCT TGGAGGAATG TGGCCTGCTG CGGAAGGGGA CAGTGCTACT GGCTGACAAC 
GTGATCTGCC CAGGTGCGCC AGACTTCCTA GCACACGTGC GCGGGAGCAG CTGCTTTGAG 
TGCACACACT ACCAATCGTT CCTGGAATAC AGGGAGGTGG TGGACGGCCT GGAGAAGGCC 
ATCTACAAGG GCCCAGGCAG CGAAGCAGGG CCCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001349757.1
CDS	512..1327
Translation	MPEAPPLLLAAVLLGLVLLVVLLLLLRHWGWGLCLIGWNEFILQPIHNLLMGDTKEQRILNHVLQHAEPGNAQSVLEAIDTYCEQKEWAMNVGDKKGKIVDAVIQEHQPSVLLELGAYCGYSAVRMARLLSPGARLITIEINPDCAAITQRMVDFAGVKDKVTLVVGASQDIIPQLKKKYDVDTLDMVFLDHWKDRYLPDTLLLEECGLLRKGTVLLADNVICPGAPDFLAHVRGSSCFECTHYQSFLEYREVVDGLEKAIYKGPGSEAGP

Target ORF information:

RefSeq Version	NM_001362828.2
Organism	Homo sapiens(human)
Definition	Homo sapiens catechol-O-methyltransferase (COMT), transcript variant 5, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001362828.2

ORF Insert Sequence:

ATGCCGGAGG CCCCGCCTCT GCTGTTGGCA GCTGTGTTGC TGGGCCTGGT GCTGCTGGTG 
GTGCTGCTGC TGCTTCTGAG GCACTGGGGC TGGGGCCTGT GCCTTATCGG CTGGAACGAG 
TTCATCCTGC AGCCCATCCA CAACCTGCTC ATGGGTGACA CCAAGGAGCA GCGCATCCTG 
AACCACGTGC TGCAGCATGC GGAGCCCGGG AACGCACAGA GCGTGCTGGA GGCCATTGAC 
ACCTACTGCG AGCAGAAGGA GTGGGCCATG AACGTGGGCG ACAAGAAAGG CAAGATCGTG 
GACGCCGTGA TTCAGGAGCA CCAGCCCTCC GTGCTGCTGG AGCTGGGGGC CTACTGTGGC 
TACTCAGCTG TGCGCATGGC CCGCCTGCTG TCACCAGGGG CGAGGCTCAT CACCATCGAG 
ATCAACCCCG ACTGTGCCGC CATCACCCAG CGGATGGTGG ATTTCGCTGG CGTGAAGGAC 
AAGGTCACCC TTGTGGTTGG AGCGTCCCAG GACATCATCC CCCAGCTGAA GAAGAAGTAT 
GATGTGGACA CACTGGACAT GGTCTTCCTC GACCACTGGA AGGACCGGTA CCTGCCGGAC 
ACGCTTCTCT TGGAGGAATG TGGCCTGCTG CGGAAGGGGA CAGTGCTACT GGCTGACAAC 
GTGATCTGCC CAGGTGCGCC AGACTTCCTA GCACACGTGC GCGGGAGCAG CTGCTTTGAG 
TGCACACACT ACCAATCGTT CCTGGAATAC AGGGAGGTGG TGGACGGCCT GGAGAAGGCC 
ATCTACAAGG GCCCAGGCAG CGAAGCAGGG CCCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

COMT ( XM_017028594.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_016884083.1 Homo sapiens catechol-O-methyltransferase (COMT), transcript variant X2, mRNA.

Price & Availability↑

CloneID	OHu23722
Clone ID Related Accession (Same CDS sequence)	XM_017028594.1 , NM_001135162.1 , NM_001135162.2 , NM_001135161.1 , NM_001135161.2 , NM_000754.4 , NM_000754.3 , NM_001362828.1 , NM_001362828.2 , XM_017028595.1
Accession Version	XM_017028594.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 816bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-06-05
Organism	Homo sapiens(human)
Product	catechol O-methyltransferase isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000022.11) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGCCGGAGG CCCCGCCTCT GCTGTTGGCA GCTGTGTTGC TGGGCCTGGT GCTGCTGGTG 
GTGCTGCTGC TGCTTCTGAG GCACTGGGGC TGGGGCCTGT GCCTTATCGG CTGGAACGAG 
TTCATCCTGC AGCCCATCCA CAACCTGCTC ATGGGTGACA CCAAGGAGCA GCGCATCCTG 
AACCACGTGC TGCAGCATGC GGAGCCCGGG AACGCACAGA GCGTGCTGGA GGCCATTGAC 
ACCTACTGCG AGCAGAAGGA GTGGGCCATG AACGTGGGCG ACAAGAAAGG CAAGATCGTG 
GACGCCGTGA TTCAGGAGCA CCAGCCCTCC GTGCTGCTGG AGCTGGGGGC CTACTGTGGC 
TACTCAGCTG TGCGCATGGC CCGCCTGCTG TCACCAGGGG CGAGGCTCAT CACCATCGAG 
ATCAACCCCG ACTGTGCCGC CATCACCCAG CGGATGGTGG ATTTCGCTGG CGTGAAGGAC 
AAGGTCACCC TTGTGGTTGG AGCGTCCCAG GACATCATCC CCCAGCTGAA GAAGAAGTAT 
GATGTGGACA CACTGGACAT GGTCTTCCTC GACCACTGGA AGGACCGGTA CCTGCCGGAC 
ACGCTTCTCT TGGAGGAATG TGGCCTGCTG CGGAAGGGGA CAGTGCTACT GGCTGACAAC 
GTGATCTGCC CAGGTGCGCC AGACTTCCTA GCACACGTGC GCGGGAGCAG CTGCTTTGAG 
TGCACACACT ACCAATCGTT CCTGGAATAC AGGGAGGTGG TGGACGGCCT GGAGAAGGCC 
ATCTACAAGG GCCCAGGCAG CGAAGCAGGG CCCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_016884083.1
CDS	474..1289
Translation	MPEAPPLLLAAVLLGLVLLVVLLLLLRHWGWGLCLIGWNEFILQPIHNLLMGDTKEQRILNHVLQHAEPGNAQSVLEAIDTYCEQKEWAMNVGDKKGKIVDAVIQEHQPSVLLELGAYCGYSAVRMARLLSPGARLITIEINPDCAAITQRMVDFAGVKDKVTLVVGASQDIIPQLKKKYDVDTLDMVFLDHWKDRYLPDTLLLEECGLLRKGTVLLADNVICPGAPDFLAHVRGSSCFECTHYQSFLEYREVVDGLEKAIYKGPGSEAGP

Target ORF information:

RefSeq Version	XM_017028594.1
Organism	Homo sapiens(human)
Definition	Homo sapiens catechol-O-methyltransferase (COMT), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017028594.1

ORF Insert Sequence:

ATGCCGGAGG CCCCGCCTCT GCTGTTGGCA GCTGTGTTGC TGGGCCTGGT GCTGCTGGTG 
GTGCTGCTGC TGCTTCTGAG GCACTGGGGC TGGGGCCTGT GCCTTATCGG CTGGAACGAG 
TTCATCCTGC AGCCCATCCA CAACCTGCTC ATGGGTGACA CCAAGGAGCA GCGCATCCTG 
AACCACGTGC TGCAGCATGC GGAGCCCGGG AACGCACAGA GCGTGCTGGA GGCCATTGAC 
ACCTACTGCG AGCAGAAGGA GTGGGCCATG AACGTGGGCG ACAAGAAAGG CAAGATCGTG 
GACGCCGTGA TTCAGGAGCA CCAGCCCTCC GTGCTGCTGG AGCTGGGGGC CTACTGTGGC 
TACTCAGCTG TGCGCATGGC CCGCCTGCTG TCACCAGGGG CGAGGCTCAT CACCATCGAG 
ATCAACCCCG ACTGTGCCGC CATCACCCAG CGGATGGTGG ATTTCGCTGG CGTGAAGGAC 
AAGGTCACCC TTGTGGTTGG AGCGTCCCAG GACATCATCC CCCAGCTGAA GAAGAAGTAT 
GATGTGGACA CACTGGACAT GGTCTTCCTC GACCACTGGA AGGACCGGTA CCTGCCGGAC 
ACGCTTCTCT TGGAGGAATG TGGCCTGCTG CGGAAGGGGA CAGTGCTACT GGCTGACAAC 
GTGATCTGCC CAGGTGCGCC AGACTTCCTA GCACACGTGC GCGGGAGCAG CTGCTTTGAG 
TGCACACACT ACCAATCGTT CCTGGAATAC AGGGAGGTGG TGGACGGCCT GGAGAAGGCC 
ATCTACAAGG GCCCAGGCAG CGAAGCAGGG CCCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

COMT ( XM_017028595.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_016884084.1 Homo sapiens catechol-O-methyltransferase (COMT), transcript variant X3, mRNA.

Price & Availability↑

CloneID	OHu23722
Clone ID Related Accession (Same CDS sequence)	XM_017028594.1 , NM_001135162.1 , NM_001135162.2 , NM_001135161.1 , NM_001135161.2 , NM_000754.4 , NM_000754.3 , NM_001362828.1 , NM_001362828.2 , XM_017028595.1
Accession Version	XM_017028595.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 816bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2018-03-25
Organism	Homo sapiens(human)
Product	catechol O-methyltransferase isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000022.11) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Homo sapiens Annotation Release 109 Annotation Version :: 109 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGCCGGAGG CCCCGCCTCT GCTGTTGGCA GCTGTGTTGC TGGGCCTGGT GCTGCTGGTG 
GTGCTGCTGC TGCTTCTGAG GCACTGGGGC TGGGGCCTGT GCCTTATCGG CTGGAACGAG 
TTCATCCTGC AGCCCATCCA CAACCTGCTC ATGGGTGACA CCAAGGAGCA GCGCATCCTG 
AACCACGTGC TGCAGCATGC GGAGCCCGGG AACGCACAGA GCGTGCTGGA GGCCATTGAC 
ACCTACTGCG AGCAGAAGGA GTGGGCCATG AACGTGGGCG ACAAGAAAGG CAAGATCGTG 
GACGCCGTGA TTCAGGAGCA CCAGCCCTCC GTGCTGCTGG AGCTGGGGGC CTACTGTGGC 
TACTCAGCTG TGCGCATGGC CCGCCTGCTG TCACCAGGGG CGAGGCTCAT CACCATCGAG 
ATCAACCCCG ACTGTGCCGC CATCACCCAG CGGATGGTGG ATTTCGCTGG CGTGAAGGAC 
AAGGTCACCC TTGTGGTTGG AGCGTCCCAG GACATCATCC CCCAGCTGAA GAAGAAGTAT 
GATGTGGACA CACTGGACAT GGTCTTCCTC GACCACTGGA AGGACCGGTA CCTGCCGGAC 
ACGCTTCTCT TGGAGGAATG TGGCCTGCTG CGGAAGGGGA CAGTGCTACT GGCTGACAAC 
GTGATCTGCC CAGGTGCGCC AGACTTCCTA GCACACGTGC GCGGGAGCAG CTGCTTTGAG 
TGCACACACT ACCAATCGTT CCTGGAATAC AGGGAGGTGG TGGACGGCCT GGAGAAGGCC 
ATCTACAAGG GCCCAGGCAG CGAAGCAGGG CCCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_016884084.1
CDS	418..1233
Translation	MPEAPPLLLAAVLLGLVLLVVLLLLLRHWGWGLCLIGWNEFILQPIHNLLMGDTKEQRILNHVLQHAEPGNAQSVLEAIDTYCEQKEWAMNVGDKKGKIVDAVIQEHQPSVLLELGAYCGYSAVRMARLLSPGARLITIEINPDCAAITQRMVDFAGVKDKVTLVVGASQDIIPQLKKKYDVDTLDMVFLDHWKDRYLPDTLLLEECGLLRKGTVLLADNVICPGAPDFLAHVRGSSCFECTHYQSFLEYREVVDGLEKAIYKGPGSEAGP

Target ORF information:

RefSeq Version	XM_017028595.1
Organism	Homo sapiens(human)
Definition	Homo sapiens catechol-O-methyltransferase (COMT), transcript variant X3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017028595.1

ORF Insert Sequence:

ATGCCGGAGG CCCCGCCTCT GCTGTTGGCA GCTGTGTTGC TGGGCCTGGT GCTGCTGGTG 
GTGCTGCTGC TGCTTCTGAG GCACTGGGGC TGGGGCCTGT GCCTTATCGG CTGGAACGAG 
TTCATCCTGC AGCCCATCCA CAACCTGCTC ATGGGTGACA CCAAGGAGCA GCGCATCCTG 
AACCACGTGC TGCAGCATGC GGAGCCCGGG AACGCACAGA GCGTGCTGGA GGCCATTGAC 
ACCTACTGCG AGCAGAAGGA GTGGGCCATG AACGTGGGCG ACAAGAAAGG CAAGATCGTG 
GACGCCGTGA TTCAGGAGCA CCAGCCCTCC GTGCTGCTGG AGCTGGGGGC CTACTGTGGC 
TACTCAGCTG TGCGCATGGC CCGCCTGCTG TCACCAGGGG CGAGGCTCAT CACCATCGAG 
ATCAACCCCG ACTGTGCCGC CATCACCCAG CGGATGGTGG ATTTCGCTGG CGTGAAGGAC 
AAGGTCACCC TTGTGGTTGG AGCGTCCCAG GACATCATCC CCCAGCTGAA GAAGAAGTAT 
GATGTGGACA CACTGGACAT GGTCTTCCTC GACCACTGGA AGGACCGGTA CCTGCCGGAC 
ACGCTTCTCT TGGAGGAATG TGGCCTGCTG CGGAAGGGGA CAGTGCTACT GGCTGACAAC 
GTGATCTGCC CAGGTGCGCC AGACTTCCTA GCACACGTGC GCGGGAGCAG CTGCTTTGAG 
TGCACACACT ACCAATCGTT CCTGGAATAC AGGGAGGTGG TGGACGGCCT GGAGAAGGCC 
ATCTACAAGG GCCCAGGCAG CGAAGCAGGG CCCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

COMT ( XM_011529886.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_011528188.1 Homo sapiens catechol-O-methyltransferase (COMT), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OHu57041
Clone ID Related Accession (Same CDS sequence)	XM_011529886.1
Accession Version	XM_011529886.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 930bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-06-05
Organism	Homo sapiens(human)
Product	catechol O-methyltransferase isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000022.11) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGATGTTGC TATGCATATT GGGAAATAAC ATCTGCTTTG CTGCCGAGCT CAGAGGAGAC 
CCCAGACCCC TCCCGCAGCC AGAGGGCTGG AGCCTGCTCA GAGGTGCTTT GAAGATGCCG 
GAGGCCCCGC CTCTGCTGTT GGCAGCTGTG TTGCTGGGCC TGGTGCTGCT GGTGGTGCTG 
CTGCTGCTTC TGAGGCACTG GGGCTGGGGC CTGTGCCTTA TCGGCTGGAA CGAGTTCATC 
CTGCAGCCCA TCCACAACCT GCTCATGGGT GACACCAAGG AGCAGCGCAT CCTGAACCAC 
GTGCTGCAGC ATGCGGAGCC CGGGAACGCA CAGAGCGTGC TGGAGGCCAT TGACACCTAC 
TGCGAGCAGA AGGAGTGGGC CATGAACGTG GGCGACAAGA AAGGCAAGAT CGTGGACGCC 
GTGATTCAGG AGCACCAGCC CTCCGTGCTG CTGGAGCTGG GGGCCTACTG TGGCTACTCA 
GCTGTGCGCA TGGCCCGCCT GCTGTCACCA GGGGCGAGGC TCATCACCAT CGAGATCAAC 
CCCGACTGTG CCGCCATCAC CCAGCGGATG GTGGATTTCG CTGGCGTGAA GGACAAGGTC 
ACCCTTGTGG TTGGAGCGTC CCAGGACATC ATCCCCCAGC TGAAGAAGAA GTATGATGTG 
GACACACTGG ACATGGTCTT CCTCGACCAC TGGAAGGACC GGTACCTGCC GGACACGCTT 
CTCTTGGAGG AATGTGGCCT GCTGCGGAAG GGGACAGTGC TACTGGCTGA CAACGTGATC 
TGCCCAGGTG CGCCAGACTT CCTAGCACAC GTGCGCGGGA GCAGCTGCTT TGAGTGCACA 
CACTACCAAT CGTTCCTGGA ATACAGGGAG GTGGTGGACG GCCTGGAGAA GGCCATCTAC 
AAGGGCCCAG GCAGCGAAGC AGGGCCCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_011528188.1
CDS	41..970
Translation	MMLLCILGNNICFAAELRGDPRPLPQPEGWSLLRGALKMPEAPPLLLAAVLLGLVLLVVLLLLLRHWGWGLCLIGWNEFILQPIHNLLMGDTKEQRILNHVLQHAEPGNAQSVLEAIDTYCEQKEWAMNVGDKKGKIVDAVIQEHQPSVLLELGAYCGYSAVRMARLLSPGARLITIEINPDCAAITQRMVDFAGVKDKVTLVVGASQDIIPQLKKKYDVDTLDMVFLDHWKDRYLPDTLLLEECGLLRKGTVLLADNVICPGAPDFLAHVRGSSCFECTHYQSFLEYREVVDGLEKAIYKGPGSEAGP

Target ORF information:

RefSeq Version	XM_011529886.1
Organism	Homo sapiens(human)
Definition	Homo sapiens catechol-O-methyltransferase (COMT), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011529886.1

ORF Insert Sequence:

ATGATGTTGC TATGCATATT GGGAAATAAC ATCTGCTTTG CTGCCGAGCT CAGAGGAGAC 
CCCAGACCCC TCCCGCAGCC AGAGGGCTGG AGCCTGCTCA GAGGTGCTTT GAAGATGCCG 
GAGGCCCCGC CTCTGCTGTT GGCAGCTGTG TTGCTGGGCC TGGTGCTGCT GGTGGTGCTG 
CTGCTGCTTC TGAGGCACTG GGGCTGGGGC CTGTGCCTTA TCGGCTGGAA CGAGTTCATC 
CTGCAGCCCA TCCACAACCT GCTCATGGGT GACACCAAGG AGCAGCGCAT CCTGAACCAC 
GTGCTGCAGC ATGCGGAGCC CGGGAACGCA CAGAGCGTGC TGGAGGCCAT TGACACCTAC 
TGCGAGCAGA AGGAGTGGGC CATGAACGTG GGCGACAAGA AAGGCAAGAT CGTGGACGCC 
GTGATTCAGG AGCACCAGCC CTCCGTGCTG CTGGAGCTGG GGGCCTACTG TGGCTACTCA 
GCTGTGCGCA TGGCCCGCCT GCTGTCACCA GGGGCGAGGC TCATCACCAT CGAGATCAAC 
CCCGACTGTG CCGCCATCAC CCAGCGGATG GTGGATTTCG CTGGCGTGAA GGACAAGGTC 
ACCCTTGTGG TTGGAGCGTC CCAGGACATC ATCCCCCAGC TGAAGAAGAA GTATGATGTG 
GACACACTGG ACATGGTCTT CCTCGACCAC TGGAAGGACC GGTACCTGCC GGACACGCTT 
CTCTTGGAGG AATGTGGCCT GCTGCGGAAG GGGACAGTGC TACTGGCTGA CAACGTGATC 
TGCCCAGGTG CGCCAGACTT CCTAGCACAC GTGCGCGGGA GCAGCTGCTT TGAGTGCACA 
CACTACCAAT CGTTCCTGGA ATACAGGGAG GTGGTGGACG GCCTGGAGAA GGCCATCTAC 
AAGGGCCCAG GCAGCGAAGC AGGGCCCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

COMT ( NM_000754.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_000745.1 Homo sapiens catechol-O-methyltransferase (COMT), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu23722
Clone ID Related Accession (Same CDS sequence)	XM_017028594.1 , NM_001135162.1 , NM_001135162.2 , NM_001135161.1 , NM_001135161.2 , NM_000754.4 , NM_000754.3 , NM_001362828.1 , NM_001362828.2 , XM_017028595.1
Accession Version	NM_000754.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 816bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2020-01-04
Organism	Homo sapiens(human)
Product	catechol O-methyltransferase isoform MB-COMT
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BX461394.2, AK290440.1 and AC005663.2. On Aug 31, 2019 this sequence version replaced NM_000754.3. Transcript Variant: This variant (1, also known as MB-COMT) represents the predominant transcript and encodes the longer isoform (MB-COMT). Variants 1, 2, 3, and 5 all encode isoform MB-COMT and may also make the shorter isoform S-COMT at a low level. MB-COMT is a membrane-bound protein. Sequence Note: This RefSeq record was created from transcript and genomic sequence data because no single transcript was available for the full length of the gene. The extent of this transcript is supported by transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK290440.1, FJ224345.1 [ECO:0000332] ##Evidence-Data-END## ##RefSeq-Attributes-START## RefSeq Select criteria :: based on manual assertion, conservation, expression, longest protein ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGCCGGAGG CCCCGCCTCT GCTGTTGGCA GCTGTGTTGC TGGGCCTGGT GCTGCTGGTG 
GTGCTGCTGC TGCTTCTGAG GCACTGGGGC TGGGGCCTGT GCCTTATCGG CTGGAACGAG 
TTCATCCTGC AGCCCATCCA CAACCTGCTC ATGGGTGACA CCAAGGAGCA GCGCATCCTG 
AACCACGTGC TGCAGCATGC GGAGCCCGGG AACGCACAGA GCGTGCTGGA GGCCATTGAC 
ACCTACTGCG AGCAGAAGGA GTGGGCCATG AACGTGGGCG ACAAGAAAGG CAAGATCGTG 
GACGCCGTGA TTCAGGAGCA CCAGCCCTCC GTGCTGCTGG AGCTGGGGGC CTACTGTGGC 
TACTCAGCTG TGCGCATGGC CCGCCTGCTG TCACCAGGGG CGAGGCTCAT CACCATCGAG 
ATCAACCCCG ACTGTGCCGC CATCACCCAG CGGATGGTGG ATTTCGCTGG CGTGAAGGAC 
AAGGTCACCC TTGTGGTTGG AGCGTCCCAG GACATCATCC CCCAGCTGAA GAAGAAGTAT 
GATGTGGACA CACTGGACAT GGTCTTCCTC GACCACTGGA AGGACCGGTA CCTGCCGGAC 
ACGCTTCTCT TGGAGGAATG TGGCCTGCTG CGGAAGGGGA CAGTGCTACT GGCTGACAAC 
GTGATCTGCC CAGGTGCGCC AGACTTCCTA GCACACGTGC GCGGGAGCAG CTGCTTTGAG 
TGCACACACT ACCAATCGTT CCTGGAATAC AGGGAGGTGG TGGACGGCCT GGAGAAGGCC 
ATCTACAAGG GCCCAGGCAG CGAAGCAGGG CCCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_000745.1
CDS	218..1033
Translation	MPEAPPLLLAAVLLGLVLLVVLLLLLRHWGWGLCLIGWNEFILQPIHNLLMGDTKEQRILNHVLQHAEPGNAQSVLEAIDTYCEQKEWAMNVGDKKGKIVDAVIQEHQPSVLLELGAYCGYSAVRMARLLSPGARLITIEINPDCAAITQRMVDFAGVKDKVTLVVGASQDIIPQLKKKYDVDTLDMVFLDHWKDRYLPDTLLLEECGLLRKGTVLLADNVICPGAPDFLAHVRGSSCFECTHYQSFLEYREVVDGLEKAIYKGPGSEAGP

Target ORF information:

RefSeq Version	NM_000754.4
Organism	Homo sapiens(human)
Definition	Homo sapiens catechol-O-methyltransferase (COMT), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_000754.4

ORF Insert Sequence:

ATGCCGGAGG CCCCGCCTCT GCTGTTGGCA GCTGTGTTGC TGGGCCTGGT GCTGCTGGTG 
GTGCTGCTGC TGCTTCTGAG GCACTGGGGC TGGGGCCTGT GCCTTATCGG CTGGAACGAG 
TTCATCCTGC AGCCCATCCA CAACCTGCTC ATGGGTGACA CCAAGGAGCA GCGCATCCTG 
AACCACGTGC TGCAGCATGC GGAGCCCGGG AACGCACAGA GCGTGCTGGA GGCCATTGAC 
ACCTACTGCG AGCAGAAGGA GTGGGCCATG AACGTGGGCG ACAAGAAAGG CAAGATCGTG 
GACGCCGTGA TTCAGGAGCA CCAGCCCTCC GTGCTGCTGG AGCTGGGGGC CTACTGTGGC 
TACTCAGCTG TGCGCATGGC CCGCCTGCTG TCACCAGGGG CGAGGCTCAT CACCATCGAG 
ATCAACCCCG ACTGTGCCGC CATCACCCAG CGGATGGTGG ATTTCGCTGG CGTGAAGGAC 
AAGGTCACCC TTGTGGTTGG AGCGTCCCAG GACATCATCC CCCAGCTGAA GAAGAAGTAT 
GATGTGGACA CACTGGACAT GGTCTTCCTC GACCACTGGA AGGACCGGTA CCTGCCGGAC 
ACGCTTCTCT TGGAGGAATG TGGCCTGCTG CGGAAGGGGA CAGTGCTACT GGCTGACAAC 
GTGATCTGCC CAGGTGCGCC AGACTTCCTA GCACACGTGC GCGGGAGCAG CTGCTTTGAG 
TGCACACACT ACCAATCGTT CCTGGAATAC AGGGAGGTGG TGGACGGCCT GGAGAAGGCC 
ATCTACAAGG GCCCAGGCAG CGAAGCAGGG CCCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

COMT ( XM_011529886.2 ) cDNA ORF clone, Homo sapiens(human) -> XP_011528188.2 Homo sapiens catechol-O-methyltransferase (COMT), transcript variant X1, mRNA.

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CloneID	OHu105217
Clone ID Related Accession (Same CDS sequence)	XM_011529886.2
Accession Version	XM_011529886.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1227bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2018-03-25
Organism	Homo sapiens(human)
Product	catechol O-methyltransferase isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000022.11) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Mar 26, 2018 this sequence version replaced XM_011529886.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Homo sapiens Annotation Release 109 Annotation Version :: 109 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGTGCAGGT GCTGTGTGGG CACGATCATG CCTGCCCTCT ACTGTGCTGG AGAGGTAAGA 
CCATCAGCCG TTTCACAGAG GAGGGAATGT GGACCTCACG GGGGTCTCAT GAGCTTGCGA 
GCCGATGGCC AGGCAGCCGG TGCAGAAGGT TCATCCATTT TGATGAACCG TGAATTCATC 
TGTACTTTAT TCATTTTAAT AACTGAATCA TACCTCATTG TATGGCTCTA CCATGTTTTA 
TTATCCATTC AGGTGCTAAC GGATGGAAGG GTTGTTTCTA CCTGTTGGCC ATTGTGGATG 
ATGTTGCTAT GCATATTGGG AAATAACATC TGCTTTGCTG CCGAGCTCAG AGGAGACCCC 
AGACCCCTCC CGCAGCCAGA GGGCTGGAGC CTGCTCAGAG GTGCTTTGAA GATGCCGGAG 
GCCCCGCCTC TGCTGTTGGC AGCTGTGTTG CTGGGCCTGG TGCTGCTGGT GGTGCTGCTG 
CTGCTTCTGA GGCACTGGGG CTGGGGCCTG TGCCTTATCG GCTGGAACGA GTTCATCCTG 
CAGCCCATCC ACAACCTGCT CATGGGTGAC ACCAAGGAGC AGCGCATCCT GAACCACGTG 
CTGCAGCATG CGGAGCCCGG GAACGCACAG AGCGTGCTGG AGGCCATTGA CACCTACTGC 
GAGCAGAAGG AGTGGGCCAT GAACGTGGGC GACAAGAAAG GCAAGATCGT GGACGCCGTG 
ATTCAGGAGC ACCAGCCCTC CGTGCTGCTG GAGCTGGGGG CCTACTGTGG CTACTCAGCT 
GTGCGCATGG CCCGCCTGCT GTCACCAGGG GCGAGGCTCA TCACCATCGA GATCAACCCC 
GACTGTGCCG CCATCACCCA GCGGATGGTG GATTTCGCTG GCGTGAAGGA CAAGGTCACC 
CTTGTGGTTG GAGCGTCCCA GGACATCATC CCCCAGCTGA AGAAGAAGTA TGATGTGGAC 
ACACTGGACA TGGTCTTCCT CGACCACTGG AAGGACCGGT ACCTGCCGGA CACGCTTCTC 
TTGGAGGAAT GTGGCCTGCT GCGGAAGGGG ACAGTGCTAC TGGCTGACAA CGTGATCTGC 
CCAGGTGCGC CAGACTTCCT AGCACACGTG CGCGGGAGCA GCTGCTTTGA GTGCACACAC 
TACCAATCGT TCCTGGAATA CAGGGAGGTG GTGGACGGCC TGGAGAAGGC CATCTACAAG 
GGCCCAGGCA GCGAAGCAGG GCCCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_011528188.2
CDS	1044..2270
Translation	MCRCCVGTIMPALYCAGEVRPSAVSQRRECGPHGGLMSLRADGQAAGAEGSSILMNREFICTLFILITESYLIVWLYHVLLSIQVLTDGRVVSTCWPLWMMLLCILGNNICFAAELRGDPRPLPQPEGWSLLRGALKMPEAPPLLLAAVLLGLVLLVVLLLLLRHWGWGLCLIGWNEFILQPIHNLLMGDTKEQRILNHVLQHAEPGNAQSVLEAIDTYCEQKEWAMNVGDKKGKIVDAVIQEHQPSVLLELGAYCGYSAVRMARLLSPGARLITIEINPDCAAITQRMVDFAGVKDKVTLVVGASQDIIPQLKKKYDVDTLDMVFLDHWKDRYLPDTLLLEECGLLRKGTVLLADNVICPGAPDFLAHVRGSSCFECTHYQSFLEYREVVDGLEKAIYKGPGSEAGP

Target ORF information:

RefSeq Version	XM_011529886.2
Organism	Homo sapiens(human)
Definition	Homo sapiens catechol-O-methyltransferase (COMT), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011529886.2

ORF Insert Sequence:

ATGTGCAGGT GCTGTGTGGG CACGATCATG CCTGCCCTCT ACTGTGCTGG AGAGGTAAGA 
CCATCAGCCG TTTCACAGAG GAGGGAATGT GGACCTCACG GGGGTCTCAT GAGCTTGCGA 
GCCGATGGCC AGGCAGCCGG TGCAGAAGGT TCATCCATTT TGATGAACCG TGAATTCATC 
TGTACTTTAT TCATTTTAAT AACTGAATCA TACCTCATTG TATGGCTCTA CCATGTTTTA 
TTATCCATTC AGGTGCTAAC GGATGGAAGG GTTGTTTCTA CCTGTTGGCC ATTGTGGATG 
ATGTTGCTAT GCATATTGGG AAATAACATC TGCTTTGCTG CCGAGCTCAG AGGAGACCCC 
AGACCCCTCC CGCAGCCAGA GGGCTGGAGC CTGCTCAGAG GTGCTTTGAA GATGCCGGAG 
GCCCCGCCTC TGCTGTTGGC AGCTGTGTTG CTGGGCCTGG TGCTGCTGGT GGTGCTGCTG 
CTGCTTCTGA GGCACTGGGG CTGGGGCCTG TGCCTTATCG GCTGGAACGA GTTCATCCTG 
CAGCCCATCC ACAACCTGCT CATGGGTGAC ACCAAGGAGC AGCGCATCCT GAACCACGTG 
CTGCAGCATG CGGAGCCCGG GAACGCACAG AGCGTGCTGG AGGCCATTGA CACCTACTGC 
GAGCAGAAGG AGTGGGCCAT GAACGTGGGC GACAAGAAAG GCAAGATCGT GGACGCCGTG 
ATTCAGGAGC ACCAGCCCTC CGTGCTGCTG GAGCTGGGGG CCTACTGTGG CTACTCAGCT 
GTGCGCATGG CCCGCCTGCT GTCACCAGGG GCGAGGCTCA TCACCATCGA GATCAACCCC 
GACTGTGCCG CCATCACCCA GCGGATGGTG GATTTCGCTG GCGTGAAGGA CAAGGTCACC 
CTTGTGGTTG GAGCGTCCCA GGACATCATC CCCCAGCTGA AGAAGAAGTA TGATGTGGAC 
ACACTGGACA TGGTCTTCCT CGACCACTGG AAGGACCGGT ACCTGCCGGA CACGCTTCTC 
TTGGAGGAAT GTGGCCTGCT GCGGAAGGGG ACAGTGCTAC TGGCTGACAA CGTGATCTGC 
CCAGGTGCGC CAGACTTCCT AGCACACGTG CGCGGGAGCA GCTGCTTTGA GTGCACACAC 
TACCAATCGT TCCTGGAATA CAGGGAGGTG GTGGACGGCC TGGAGAAGGC CATCTACAAG 
GGCCCAGGCA GCGAAGCAGG GCCCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Gene Symbol	COMT
Entrez Gene ID	1312
Full Name	catechol-O-methyltransferase
Synonyms	HEL-S-98n
General protein information	Preferred Names catechol-O-methyltransferase Names catechol O-methyltransferase catechol-O-methyltransferase isoform epididymis secretory sperm binding protein Li 98n testicular tissue protein Li 42
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 22 Map Location: 22q11.21
Summary	Catechol-O-methyltransferase catalyzes the transfer of a methyl group from S-adenosylmethionine to catecholamines, including the neurotransmitters dopamine, epinephrine, and norepinephrine. This O-methylation results in one of the major degradative pathways of the catecholamine transmitters. In addition to its role in the metabolism of endogenous substances, COMT is important in the metabolism of catechol drugs used in the treatment of hypertension, asthma, and Parkinson disease. COMT is found in two forms in tissues, a soluble form (S-COMT) and a membrane-bound form (MB-COMT). The differences between S-COMT and MB-COMT reside within the N-termini. Several transcript variants are formed through the use of alternative translation initiation sites and promoters. [provided by RefSeq, Sep 2008].
Disorder MIM:	116790
Disorder Html:	{Schizophrenia, susceptibility to}, 181500 (3); {Panic disorder, susceptibility to}, 167870 (3)

Bos taurus (cattle)	COMT	NP_001095787.1
Schizosaccharomyces pombe (fission yeast)	SPBC119.03	NP_595284.1
Neurospora crassa	NCU07919	XP_962435.2
Xenopus tropicalis (tropical clawed frog)	comt	NP_001016357.1
Xenopus tropicalis (tropical clawed frog)	comt.2	NP_001017157.1
Homo sapiens (human)	COMT	NP_001128633.1
Mus musculus (house mouse)	Comt	NP_001104532.1
Magnaporthe oryzae (rice blast fungus)	MGG_00015	XP_003719132.1
Gallus gallus (chicken)	COMT	XP_001233014.1
Pan troglodytes (chimpanzee)	COMT	XP_514984.2
Canis lupus familiaris (dog)	COMT	NP_001004074.1
Rattus norvegicus (Norway rat)	Comt	NP_036663.1
Schizosaccharomyces pombe (fission yeast)	SPBPB21E7.04c	NP_001018770.1
Xenopus tropicalis (tropical clawed frog)	LOC100135405	NP_001107540.1
	COMT	XP_001105683.1

Next-day Shipping ORF Clones ( in default vector with tag)
1 Clone	30% OFF
2-4 Clone	40% OFF
5 or more Clone	50% OFF
All Other ORF Clones
30% OFF

COMT cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

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