OSCAR cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	OSCAR
Entrez Gene ID	126014
Full Name	osteoclast associated, immunoglobulin-like receptor
Synonyms	PIGR3,PIgR-3
General protein information	Preferred Names osteoclast associated, immunoglobulin-like receptor Names osteoclast-associated immunoglobulin-like receptor osteoclast associated receptor OSCAR-S1 osteoclast associated receptor OSCAR-S2 poly-Ig receptor 3 polymeric immunoglobulin receptor 3
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 19 Map Location: 19q13.42
Summary	Osteoclasts are multinucleated cells that resorb bone and are essential for bone homeostasis. This gene encodes an osteoclast-associated receptor (OSCAR), which is a member of the leukocyte receptor complex protein family that plays critical roles in the regulation of both innate and adaptive immune responses. The encoded protein may play a role in oxidative stress-mediated atherogenesis as well as monocyte adhesion. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2013].
Disorder MIM:	606862

mRNA and Protein(s)

mRNA	Protein	Name
NM_133168.4	NP_573398.2	osteoclast-associated immunoglobulin-like receptor isoform 5 precursor
NM_001282349.1	NP_001269278.1	osteoclast-associated immunoglobulin-like receptor isoform 6 precursor
NM_130771.4	NP_570127.3	osteoclast-associated immunoglobulin-like receptor isoform 3 precursor
NM_133169.4	NP_573399.2	osteoclast-associated immunoglobulin-like receptor isoform 4 precursor
NM_206818.2	NP_996554.2	osteoclast-associated immunoglobulin-like receptor isoform 1 precursor
NM_001282350.1	NP_001269279.1	osteoclast-associated immunoglobulin-like receptor isoform 7 precursor

Pathways from BioSystems

Homologies

Rattus norvegicus (Norway rat)	Oscar	NP_001171902.1
Pan troglodytes (chimpanzee)	OSCAR	XP_003316709.1
Mus musculus (house mouse)	Oscar	NP_783440.1
Homo sapiens (human)	OSCAR	NP_570127.3
Canis lupus familiaris (dog)	OSCAR	XP_541429.4
Bos taurus (cattle)	OSCAR	XP_002695502.1

Gene Ontology
Bibliography

Related articles in PubMed

Osteoclast-Associated Receptor (OSCAR) Distribution in the Synovial Tissues of Patients with Active RA and TNF-? and RANKL Regulation of Expression by Osteoclasts In Vitro.
Dharmapatni AASSK, Algate K, Coleman R, Lorimer M, Cantley MD, Smith MD, Wechalekar MD, Crotti TN
Inflammation40(5)1566-1575(2017 Oct)

OSCAR-collagen signaling in monocytes plays a proinflammatory role and may contribute to the pathogenesis of rheumatoid arthritis.
Schultz HS, Guo L, Keller P, Fleetwood AJ, Sun M, Guo W, Ma C, Hamilton JA, Bj?rkdahl O, Berchtold MW, Panina S
European journal of immunology46(4)952-63(2016 Apr)

Structural basis for collagen recognition by the immune receptor OSCAR.
Zhou L, Hinerman JM, Blaszczyk M, Miller JL, Conrady DG, Barrow AD, Chirgadze DY, Bihan D, Farndale RW, Herr AB
Blood127(5)529-37(2016 Feb)

OSCAR is a receptor for surfactant protein D that activates TNF-? release from human CCR2+ inflammatory monocytes.
Barrow AD, Palarasah Y, Bugatti M, Holehouse AS, Byers DE, Holtzman MJ, Vermi W, Skj?dt K, Crouch E, Colonna M
Journal of immunology (Baltimore, Md. : 1950)194(7)3317-26(2015 Apr)

Levels of soluble osteoclast-associated receptor (sOSCAR) in rheumatoid arthritis: link to disease severity and cardiovascular risk.
Ndongo-Thiam N, de Sallmard G, Kastrup J, Miossec P
Annals of the rheumatic diseases73(6)1276-7(2014 Jun)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

OSCAR can play a proinflammatory role in monocyte-derived cells and may contribute crucially on multiple levels to rheumatoid arthritis pathogenesis.
Title: OSCAR-collagen signaling in monocytes plays a proinflammatory role and may contribute to the pathogenesis of rheumatoid arthritis.

Each domain of OSCAR binds a collagen triple-helical peptide; the primary site is on the C-terminal domain in contrast to GPVI and LAIR-1.
Title: Structural basis for collagen recognition by the immune receptor OSCAR.

OSCAR is a receptor for surfactant protein D that activates TNF-alpha release from human CCR2+ inflammatory monocytes.
Title: OSCAR is a receptor for surfactant protein D that activates TNF-? release from human CCR2+ inflammatory monocytes.

Plasma OSCAR level was higher in the serum of RA patients than controls, and higher in patients with destructive RA rather than non-destructive RA.
Title: Levels of soluble osteoclast-associated receptor (sOSCAR) in rheumatoid arthritis: link to disease severity and cardiovascular risk.

Data indicate that osteoclast associated receptor (OSCAR) was strongly expressed by the vasculature of active rheumatoid arthritis (RA) patients.
Title: The immunoreceptor tyrosine-based activation motif (ITAM) -related factors are increased in synovial tissue and vasculature of rheumatoid arthritic joints.

The following OSCAR gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the OSCAR cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu10290	NM_133169.4 Latest version!	Homo sapiens osteoclast associated Ig-like receptor (OSCAR), transcript variant 4, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
OHu11186	NM_206818.2 Latest version!	Homo sapiens osteoclast associated Ig-like receptor (OSCAR), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$99.50-$139.30 $199.00
OHu10546	NM_130771.4 Latest version!	Homo sapiens osteoclast associated Ig-like receptor (OSCAR), transcript variant 3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$216.30 $309.00
OHu10964	NM_133168.4 Latest version!	Homo sapiens osteoclast associated Ig-like receptor (OSCAR), transcript variant 5, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$188.30 $269.00
OHu11342	NM_001282349.1 Latest version!	Homo sapiens osteoclast associated Ig-like receptor (OSCAR), transcript variant 6, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$139.30 $199.00
OHu11518	NM_001282350.1 Latest version!	Homo sapiens osteoclast associated Ig-like receptor (OSCAR), transcript variant 7, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$139.30 $199.00

ORF Online Only Promotion

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

OSCAR ( NM_133169.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_573399.2 Homo sapiens osteoclast associated Ig-like receptor (OSCAR), transcript variant 4, mRNA.

Price & Availability↑

CloneID	OHu10290
Clone ID Related Accession (Same CDS sequence)	NM_133169.4
Accession Version	NM_133169.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 792bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-08-05
Organism	Homo sapiens(human)
Product	osteoclast-associated immunoglobulin-like receptor isoform 4 precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BC035023.2, AC245052.3, AF391162.1 and AF251702.1. On Aug 31, 2013 this sequence version replaced NM_133169.3. Transcript Variant: This variant (4) lacks an in-frame exon in the central coding region and lacks an internal segment in its 3' coding region, compared to variant 1. The encoded isoform (4) is shorter and has a distinct C-terminus, compared to isoform 1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## CDS exon combination :: AF391162.1, AF251702.1 [ECO:0000331] RNAseq introns :: mixed/partial sample support SAMEA2147920 [ECO:0000350] ##Evidence-Data-END## ##RefSeq-Attributes-START## CDS uses downstream in-frame AUG :: downstream AUG is associated with N-terminal localization signal (PMID:11805147) ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGGCCCTGG TGCTGATCCT CCAGCTGCTG ACCCTCTGGC CTCTGTGTCA CACAGACATC 
ACTCCGTCTG TCCCCCCAGC TTCATACCAC CCTAAGCCAT GGCTGGGAGC TCAGCCGGCT 
ACAGTTGTGA CCCCTGGGGT CAACGTGACC TTGAGATGCC GGGCACCCCA ACCCGCTTGG 
AGATTTGGAC TTTTCAAGCC TGGAGAGATC GCTCCCCTTC TCTTCCGGGA TGTGTCCTCC 
GAGCTGGCAG AATTCTTTCT GGAGGAGGTG ACTCCAGCCC AAGGGGGAAG TTACCGCTGC 
TGCTACCGAA GGCCAGACTG GGGGCCGGGT GTCTGGTCCC AGCCCAGCGA TGTCCTGGAG 
CTGCTGGTGA CAGAGGAGCT GCCGCGGCCG TCGCTGGTGG CGCTGCCCGG GCCGGTGGTG 
GGTCCTGGCG CCAACGTGAG CCTGCGCTGC GCGGGCCGCC TGCGGAACAT GAGCTTCGTG 
CTGTACCGCG AGGGCGTGGC GGCCCCGCTG CAGTACCGCC ACTCCGCGCA GCCCTGGGCC 
GACTTCACGC TGCTGGGCGC CCGCGCCCCC GGCACCTACA GCTGCTACTA TCACACGCCC 
TCCGCGCCCT ACGTGCTGTC GCAGCGCAGC GAGGTGCTGG TCATCAGCTG GGAAGACTCT 
GGCTCCTCCG ACTACACCCG GGGGAACCTA GTCCGCCTGG GGCTGGCCGG GCTGGTCCTC 
ATCTCCCTGG GCGCGCTGGT CACTTTTGAC TGGCGCAGTC AGAACCGCGC TCCTGCTGGT 
ATCCGCCCCT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_573399.2
CDS	193..984
Translation	MALVLILQLLTLWPLCHTDITPSVPPASYHPKPWLGAQPATVVTPGVNVTLRCRAPQPAWRFGLFKPGEIAPLLFRDVSSELAEFFLEEVTPAQGGSYRCCYRRPDWGPGVWSQPSDVLELLVTEELPRPSLVALPGPVVGPGANVSLRCAGRLRNMSFVLYREGVAAPLQYRHSAQPWADFTLLGARAPGTYSCYYHTPSAPYVLSQRSEVLVISWEDSGSSDYTRGNLVRLGLAGLVLISLGALVTFDWRSQNRAPAGIRP

Target ORF information:

RefSeq Version	NM_133169.4
Organism	Homo sapiens(human)
Definition	Homo sapiens osteoclast associated Ig-like receptor (OSCAR), transcript variant 4, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_133169.4

ORF Insert Sequence:

ATGGCCCTGG TGCTGATCCT CCAGCTGCTG ACCCTCTGGC CTCTGTGTCA CACAGACATC 
ACTCCGTCTG TCCCCCCAGC TTCATACCAC CCTAAGCCAT GGCTGGGAGC TCAGCCGGCT 
ACAGTTGTGA CCCCTGGGGT CAACGTGACC TTGAGATGCC GGGCACCCCA ACCCGCTTGG 
AGATTTGGAC TTTTCAAGCC TGGAGAGATC GCTCCCCTTC TCTTCCGGGA TGTGTCCTCC 
GAGCTGGCAG AATTCTTTCT GGAGGAGGTG ACTCCAGCCC AAGGGGGAAG TTACCGCTGC 
TGCTACCGAA GGCCAGACTG GGGGCCGGGT GTCTGGTCCC AGCCCAGCGA TGTCCTGGAG 
CTGCTGGTGA CAGAGGAGCT GCCGCGGCCG TCGCTGGTGG CGCTGCCCGG GCCGGTGGTG 
GGTCCTGGCG CCAACGTGAG CCTGCGCTGC GCGGGCCGCC TGCGGAACAT GAGCTTCGTG 
CTGTACCGCG AGGGCGTGGC GGCCCCGCTG CAGTACCGCC ACTCCGCGCA GCCCTGGGCC 
GACTTCACGC TGCTGGGCGC CCGCGCCCCC GGCACCTACA GCTGCTACTA TCACACGCCC 
TCCGCGCCCT ACGTGCTGTC GCAGCGCAGC GAGGTGCTGG TCATCAGCTG GGAAGACTCT 
GGCTCCTCCG ACTACACCCG GGGGAACCTA GTCCGCCTGG GGCTGGCCGG GCTGGTCCTC 
ATCTCCCTGG GCGCGCTGGT CACTTTTGAC TGGCGCAGTC AGAACCGCGC TCCTGCTGGT 
ATCCGCCCCT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

OSCAR ( NM_206818.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_996554.2 Homo sapiens osteoclast associated Ig-like receptor (OSCAR), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu11186
Clone ID Related Accession (Same CDS sequence)	NM_206818.2
Accession Version	NM_206818.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 861bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-08-04
Organism	Homo sapiens(human)
Product	osteoclast-associated immunoglobulin-like receptor isoform 1 precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BC035023.2, AC245052.3, AK130199.1, AF474153.1, AF251702.1 and AF391162.1. On Aug 31, 2013 this sequence version replaced NM_206818.1. Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (1). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## CDS exon combination :: AK130199.1 [ECO:0000331] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1968540 [ECO:0000350] ##Evidence-Data-END## ##RefSeq-Attributes-START## CDS uses downstream in-frame AUG :: downstream AUG is associated with N-terminal localization signal (PMID:11805147) ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGGCCCTGG TGCTGATCCT CCAGCTGCTG ACCCTCTGGC CTCTGTGTCA CACAGACATC 
ACTCCGTCTG TGGCCATTAT AGTCCCCCCA GCTTCATACC ACCCTAAGCC ATGGCTGGGA 
GCTCAGCCGG CTACAGTTGT GACCCCTGGG GTCAACGTGA CCTTGAGATG CCGGGCACCC 
CAACCCGCTT GGAGATTTGG ACTTTTCAAG CCTGGAGAGA TCGCTCCCCT TCTCTTCCGG 
GATGTGTCCT CCGAGCTGGC AGAATTCTTT CTGGAGGAGG TGACTCCAGC CCAAGGGGGA 
AGTTACCGCT GCTGCTACCG AAGGCCAGAC TGGGGGCCGG GTGTCTGGTC CCAGCCCAGC 
GATGTCCTGG AGCTGCTGGT GACAGAGGAG CTGCCGCGGC CGTCGCTGGT GGCGCTGCCC 
GGGCCGGTGG TGGGTCCTGG CGCCAACGTG AGCCTGCGCT GCGCGGGCCG CCTGCGGAAC 
ATGAGCTTCG TGCTGTACCG CGAGGGCGTG GCGGCCCCGC TGCAGTACCG CCACTCCGCG 
CAGCCCTGGG CCGACTTCAC GCTGCTGGGC GCCCGCGCCC CCGGCACCTA CAGCTGCTAC 
TATCACACGC CCTCCGCGCC CTACGTGCTG TCGCAGCGCA GCGAGGTGCT GGTCATCAGC 
TGGGAAGGTG AGGGCCCTGA GGCCCGGCCC GCCTCCTCCG CCCCAGGAAT GCAGGCCCCA 
GGACCTCCGC CCTCAGACCC AGGAGCCCAG GCCCCCAGCC TCTCCTCCTT CAGACCCAGG 
GGTCTAGTCC TGCAGCCCCT CCTCCCTCAG ACCCAGGATT CCTGGGACCC AGCCCCTCCT 
CCCTCAGATC CAGGAGTCTA G

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_996554.2
CDS	193..1053
Translation	MALVLILQLLTLWPLCHTDITPSVAIIVPPASYHPKPWLGAQPATVVTPGVNVTLRCRAPQPAWRFGLFKPGEIAPLLFRDVSSELAEFFLEEVTPAQGGSYRCCYRRPDWGPGVWSQPSDVLELLVTEELPRPSLVALPGPVVGPGANVSLRCAGRLRNMSFVLYREGVAAPLQYRHSAQPWADFTLLGARAPGTYSCYYHTPSAPYVLSQRSEVLVISWEGEGPEARPASSAPGMQAPGPPPSDPGAQAPSLSSFRPRGLVLQPLLPQTQDSWDPAPPPSDPGV

Target ORF information:

RefSeq Version	NM_206818.2
Organism	Homo sapiens(human)
Definition	Homo sapiens osteoclast associated Ig-like receptor (OSCAR), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_206818.2

ORF Insert Sequence:

ATGGCCCTGG TGCTGATCCT CCAGCTGCTG ACCCTCTGGC CTCTGTGTCA CACAGACATC 
ACTCCGTCTG TGGCCATTAT AGTCCCCCCA GCTTCATACC ACCCTAAGCC ATGGCTGGGA 
GCTCAGCCGG CTACAGTTGT GACCCCTGGG GTCAACGTGA CCTTGAGATG CCGGGCACCC 
CAACCCGCTT GGAGATTTGG ACTTTTCAAG CCTGGAGAGA TCGCTCCCCT TCTCTTCCGG 
GATGTGTCCT CCGAGCTGGC AGAATTCTTT CTGGAGGAGG TGACTCCAGC CCAAGGGGGA 
AGTTACCGCT GCTGCTACCG AAGGCCAGAC TGGGGGCCGG GTGTCTGGTC CCAGCCCAGC 
GATGTCCTGG AGCTGCTGGT GACAGAGGAG CTGCCGCGGC CGTCGCTGGT GGCGCTGCCC 
GGGCCGGTGG TGGGTCCTGG CGCCAACGTG AGCCTGCGCT GCGCGGGCCG CCTGCGGAAC 
ATGAGCTTCG TGCTGTACCG CGAGGGCGTG GCGGCCCCGC TGCAGTACCG CCACTCCGCG 
CAGCCCTGGG CCGACTTCAC GCTGCTGGGC GCCCGCGCCC CCGGCACCTA CAGCTGCTAC 
TATCACACGC CCTCCGCGCC CTACGTGCTG TCGCAGCGCA GCGAGGTGCT GGTCATCAGC 
TGGGAAGGTG AGGGCCCTGA GGCCCGGCCC GCCTCCTCCG CCCCAGGAAT GCAGGCCCCA 
GGACCTCCGC CCTCAGACCC AGGAGCCCAG GCCCCCAGCC TCTCCTCCTT CAGACCCAGG 
GGTCTAGTCC TGCAGCCCCT CCTCCCTCAG ACCCAGGATT CCTGGGACCC AGCCCCTCCT 
CCCTCAGATC CAGGAGTCTA G

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

OSCAR ( NM_130771.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_570127.3 Homo sapiens osteoclast associated Ig-like receptor (OSCAR), transcript variant 3, mRNA.

Price & Availability↑

CloneID	OHu10546
Clone ID Related Accession (Same CDS sequence)	NM_130771.4
Accession Version	NM_130771.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 804bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-08-04
Organism	Homo sapiens(human)
Product	osteoclast-associated immunoglobulin-like receptor isoform 3 precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BC035023.2, AC245052.3, AF391163.1, AF251702.1 and AF391162.1. On Aug 31, 2013 this sequence version replaced NM_130771.3. Transcript Variant: This variant (3) lacks an internal segment in its 3' coding region, compared to variant 1. The encoded isoform (3) has a shorter and distinct C-terminus, compared to isoform 1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## CDS exon combination :: AF391163.1 [ECO:0000331] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1968540 [ECO:0000350] ##Evidence-Data-END## ##RefSeq-Attributes-START## CDS uses downstream in-frame AUG :: downstream AUG is associated with N-terminal localization signal (PMID:11805147) ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGGCCCTGG TGCTGATCCT CCAGCTGCTG ACCCTCTGGC CTCTGTGTCA CACAGACATC 
ACTCCGTCTG TGGCCATTAT AGTCCCCCCA GCTTCATACC ACCCTAAGCC ATGGCTGGGA 
GCTCAGCCGG CTACAGTTGT GACCCCTGGG GTCAACGTGA CCTTGAGATG CCGGGCACCC 
CAACCCGCTT GGAGATTTGG ACTTTTCAAG CCTGGAGAGA TCGCTCCCCT TCTCTTCCGG 
GATGTGTCCT CCGAGCTGGC AGAATTCTTT CTGGAGGAGG TGACTCCAGC CCAAGGGGGA 
AGTTACCGCT GCTGCTACCG AAGGCCAGAC TGGGGGCCGG GTGTCTGGTC CCAGCCCAGC 
GATGTCCTGG AGCTGCTGGT GACAGAGGAG CTGCCGCGGC CGTCGCTGGT GGCGCTGCCC 
GGGCCGGTGG TGGGTCCTGG CGCCAACGTG AGCCTGCGCT GCGCGGGCCG CCTGCGGAAC 
ATGAGCTTCG TGCTGTACCG CGAGGGCGTG GCGGCCCCGC TGCAGTACCG CCACTCCGCG 
CAGCCCTGGG CCGACTTCAC GCTGCTGGGC GCCCGCGCCC CCGGCACCTA CAGCTGCTAC 
TATCACACGC CCTCCGCGCC CTACGTGCTG TCGCAGCGCA GCGAGGTGCT GGTCATCAGC 
TGGGAAGACT CTGGCTCCTC CGACTACACC CGGGGGAACC TAGTCCGCCT GGGGCTGGCC 
GGGCTGGTCC TCATCTCCCT GGGCGCGCTG GTCACTTTTG ACTGGCGCAG TCAGAACCGC 
GCTCCTGCTG GTATCCGCCC CTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_570127.3
CDS	193..996
Translation	MALVLILQLLTLWPLCHTDITPSVAIIVPPASYHPKPWLGAQPATVVTPGVNVTLRCRAPQPAWRFGLFKPGEIAPLLFRDVSSELAEFFLEEVTPAQGGSYRCCYRRPDWGPGVWSQPSDVLELLVTEELPRPSLVALPGPVVGPGANVSLRCAGRLRNMSFVLYREGVAAPLQYRHSAQPWADFTLLGARAPGTYSCYYHTPSAPYVLSQRSEVLVISWEDSGSSDYTRGNLVRLGLAGLVLISLGALVTFDWRSQNRAPAGIRP

Target ORF information:

RefSeq Version	NM_130771.4
Organism	Homo sapiens(human)
Definition	Homo sapiens osteoclast associated Ig-like receptor (OSCAR), transcript variant 3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_130771.4

ORF Insert Sequence:

ATGGCCCTGG TGCTGATCCT CCAGCTGCTG ACCCTCTGGC CTCTGTGTCA CACAGACATC 
ACTCCGTCTG TGGCCATTAT AGTCCCCCCA GCTTCATACC ACCCTAAGCC ATGGCTGGGA 
GCTCAGCCGG CTACAGTTGT GACCCCTGGG GTCAACGTGA CCTTGAGATG CCGGGCACCC 
CAACCCGCTT GGAGATTTGG ACTTTTCAAG CCTGGAGAGA TCGCTCCCCT TCTCTTCCGG 
GATGTGTCCT CCGAGCTGGC AGAATTCTTT CTGGAGGAGG TGACTCCAGC CCAAGGGGGA 
AGTTACCGCT GCTGCTACCG AAGGCCAGAC TGGGGGCCGG GTGTCTGGTC CCAGCCCAGC 
GATGTCCTGG AGCTGCTGGT GACAGAGGAG CTGCCGCGGC CGTCGCTGGT GGCGCTGCCC 
GGGCCGGTGG TGGGTCCTGG CGCCAACGTG AGCCTGCGCT GCGCGGGCCG CCTGCGGAAC 
ATGAGCTTCG TGCTGTACCG CGAGGGCGTG GCGGCCCCGC TGCAGTACCG CCACTCCGCG 
CAGCCCTGGG CCGACTTCAC GCTGCTGGGC GCCCGCGCCC CCGGCACCTA CAGCTGCTAC 
TATCACACGC CCTCCGCGCC CTACGTGCTG TCGCAGCGCA GCGAGGTGCT GGTCATCAGC 
TGGGAAGACT CTGGCTCCTC CGACTACACC CGGGGGAACC TAGTCCGCCT GGGGCTGGCC 
GGGCTGGTCC TCATCTCCCT GGGCGCGCTG GTCACTTTTG ACTGGCGCAG TCAGAACCGC 
GCTCCTGCTG GTATCCGCCC CTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

OSCAR ( NM_133168.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_573398.2 Homo sapiens osteoclast associated Ig-like receptor (OSCAR), transcript variant 5, mRNA.

Price & Availability↑

CloneID	OHu10964
Clone ID Related Accession (Same CDS sequence)	NM_133168.4
Accession Version	NM_133168.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 759bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-08-04
Organism	Homo sapiens(human)
Product	osteoclast-associated immunoglobulin-like receptor isoform 5 precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BC035023.2, AC245052.3, AF391164.1, AF251702.1 and AF391162.1. On Aug 31, 2013 this sequence version replaced NM_133168.3. Transcript Variant: This variant (5) lacks two in-frame exons in the central coding region and lacks an internal segment in its 3' coding region, compared to variant 1. The encoded isoform (5) is shorter and has a distinct C-terminus, compared to isoform 1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## CDS exon combination :: AF391164.1 [ECO:0000331] RNAseq introns :: mixed/partial sample support SAMEA2147920 [ECO:0000350] ##Evidence-Data-END## ##RefSeq-Attributes-START## CDS uses downstream in-frame AUG :: downstream AUG is associated with N-terminal localization signal (PMID:11805147) ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGGCCCTGG TGCTGATCCT CCAGCTGCTG ACCCTCTTCC CCCCAGCTTC ATACCACCCT 
AAGCCATGGC TGGGAGCTCA GCCGGCTACA GTTGTGACCC CTGGGGTCAA CGTGACCTTG 
AGATGCCGGG CACCCCAACC CGCTTGGAGA TTTGGACTTT TCAAGCCTGG AGAGATCGCT 
CCCCTTCTCT TCCGGGATGT GTCCTCCGAG CTGGCAGAAT TCTTTCTGGA GGAGGTGACT 
CCAGCCCAAG GGGGAAGTTA CCGCTGCTGC TACCGAAGGC CAGACTGGGG GCCGGGTGTC 
TGGTCCCAGC CCAGCGATGT CCTGGAGCTG CTGGTGACAG AGGAGCTGCC GCGGCCGTCG 
CTGGTGGCGC TGCCCGGGCC GGTGGTGGGT CCTGGCGCCA ACGTGAGCCT GCGCTGCGCG 
GGCCGCCTGC GGAACATGAG CTTCGTGCTG TACCGCGAGG GCGTGGCGGC CCCGCTGCAG 
TACCGCCACT CCGCGCAGCC CTGGGCCGAC TTCACGCTGC TGGGCGCCCG CGCCCCCGGC 
ACCTACAGCT GCTACTATCA CACGCCCTCC GCGCCCTACG TGCTGTCGCA GCGCAGCGAG 
GTGCTGGTCA TCAGCTGGGA AGACTCTGGC TCCTCCGACT ACACCCGGGG GAACCTAGTC 
CGCCTGGGGC TGGCCGGGCT GGTCCTCATC TCCCTGGGCG CGCTGGTCAC TTTTGACTGG 
CGCAGTCAGA ACCGCGCTCC TGCTGGTATC CGCCCCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_573398.2
CDS	193..951
Translation	MALVLILQLLTLFPPASYHPKPWLGAQPATVVTPGVNVTLRCRAPQPAWRFGLFKPGEIAPLLFRDVSSELAEFFLEEVTPAQGGSYRCCYRRPDWGPGVWSQPSDVLELLVTEELPRPSLVALPGPVVGPGANVSLRCAGRLRNMSFVLYREGVAAPLQYRHSAQPWADFTLLGARAPGTYSCYYHTPSAPYVLSQRSEVLVISWEDSGSSDYTRGNLVRLGLAGLVLISLGALVTFDWRSQNRAPAGIRP

Target ORF information:

RefSeq Version	NM_133168.4
Organism	Homo sapiens(human)
Definition	Homo sapiens osteoclast associated Ig-like receptor (OSCAR), transcript variant 5, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_133168.4

ORF Insert Sequence:

ATGGCCCTGG TGCTGATCCT CCAGCTGCTG ACCCTCTTCC CCCCAGCTTC ATACCACCCT 
AAGCCATGGC TGGGAGCTCA GCCGGCTACA GTTGTGACCC CTGGGGTCAA CGTGACCTTG 
AGATGCCGGG CACCCCAACC CGCTTGGAGA TTTGGACTTT TCAAGCCTGG AGAGATCGCT 
CCCCTTCTCT TCCGGGATGT GTCCTCCGAG CTGGCAGAAT TCTTTCTGGA GGAGGTGACT 
CCAGCCCAAG GGGGAAGTTA CCGCTGCTGC TACCGAAGGC CAGACTGGGG GCCGGGTGTC 
TGGTCCCAGC CCAGCGATGT CCTGGAGCTG CTGGTGACAG AGGAGCTGCC GCGGCCGTCG 
CTGGTGGCGC TGCCCGGGCC GGTGGTGGGT CCTGGCGCCA ACGTGAGCCT GCGCTGCGCG 
GGCCGCCTGC GGAACATGAG CTTCGTGCTG TACCGCGAGG GCGTGGCGGC CCCGCTGCAG 
TACCGCCACT CCGCGCAGCC CTGGGCCGAC TTCACGCTGC TGGGCGCCCG CGCCCCCGGC 
ACCTACAGCT GCTACTATCA CACGCCCTCC GCGCCCTACG TGCTGTCGCA GCGCAGCGAG 
GTGCTGGTCA TCAGCTGGGA AGACTCTGGC TCCTCCGACT ACACCCGGGG GAACCTAGTC 
CGCCTGGGGC TGGCCGGGCT GGTCCTCATC TCCCTGGGCG CGCTGGTCAC TTTTGACTGG 
CGCAGTCAGA ACCGCGCTCC TGCTGGTATC CGCCCCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

OSCAR ( NM_001282349.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001269278.1 Homo sapiens osteoclast associated Ig-like receptor (OSCAR), transcript variant 6, mRNA.

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CloneID	OHu11342
Clone ID Related Accession (Same CDS sequence)	NM_001282349.1
Accession Version	NM_001282349.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 849bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-08-04
Organism	Homo sapiens(human)
Product	osteoclast-associated immunoglobulin-like receptor isoform 6 precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BC035023.2, AC245052.3, AF474153.1, AF251702.1 and AF391162.1. On or before Aug 31, 2013 this sequence version replaced XM_005277245.1, XM_005277296.1, XM_005278254.1, XM_005258503.1, XM_005277067.1, XM_005277094.1, XM_005277130.1, XM_005277155.1, XM_005277177.1, XM_005277200.1. Transcript Variant: This variant (6) lacks an in-frame exon in the central coding region, compared to variant 1. The encoded isoform (6) is shorter, compared to isoform 1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC035023.2, BG722509.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA2147920 [ECO:0000350] ##Evidence-Data-END## ##RefSeq-Attributes-START## CDS uses downstream in-frame AUG :: downstream AUG is associated with N-terminal localization signal (PMID:11805147) RefSeq Select criteria :: based on conservation, expression ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGGCCCTGG TGCTGATCCT CCAGCTGCTG ACCCTCTGGC CTCTGTGTCA CACAGACATC 
ACTCCGTCTG TCCCCCCAGC TTCATACCAC CCTAAGCCAT GGCTGGGAGC TCAGCCGGCT 
ACAGTTGTGA CCCCTGGGGT CAACGTGACC TTGAGATGCC GGGCACCCCA ACCCGCTTGG 
AGATTTGGAC TTTTCAAGCC TGGAGAGATC GCTCCCCTTC TCTTCCGGGA TGTGTCCTCC 
GAGCTGGCAG AATTCTTTCT GGAGGAGGTG ACTCCAGCCC AAGGGGGAAG TTACCGCTGC 
TGCTACCGAA GGCCAGACTG GGGGCCGGGT GTCTGGTCCC AGCCCAGCGA TGTCCTGGAG 
CTGCTGGTGA CAGAGGAGCT GCCGCGGCCG TCGCTGGTGG CGCTGCCCGG GCCGGTGGTG 
GGTCCTGGCG CCAACGTGAG CCTGCGCTGC GCGGGCCGCC TGCGGAACAT GAGCTTCGTG 
CTGTACCGCG AGGGCGTGGC GGCCCCGCTG CAGTACCGCC ACTCCGCGCA GCCCTGGGCC 
GACTTCACGC TGCTGGGCGC CCGCGCCCCC GGCACCTACA GCTGCTACTA TCACACGCCC 
TCCGCGCCCT ACGTGCTGTC GCAGCGCAGC GAGGTGCTGG TCATCAGCTG GGAAGGTGAG 
GGCCCTGAGG CCCGGCCCGC CTCCTCCGCC CCAGGAATGC AGGCCCCAGG ACCTCCGCCC 
TCAGACCCAG GAGCCCAGGC CCCCAGCCTC TCCTCCTTCA GACCCAGGGG TCTAGTCCTG 
CAGCCCCTCC TCCCTCAGAC CCAGGATTCC TGGGACCCAG CCCCTCCTCC CTCAGATCCA 
GGAGTCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001269278.1
CDS	193..1041
Translation	MALVLILQLLTLWPLCHTDITPSVPPASYHPKPWLGAQPATVVTPGVNVTLRCRAPQPAWRFGLFKPGEIAPLLFRDVSSELAEFFLEEVTPAQGGSYRCCYRRPDWGPGVWSQPSDVLELLVTEELPRPSLVALPGPVVGPGANVSLRCAGRLRNMSFVLYREGVAAPLQYRHSAQPWADFTLLGARAPGTYSCYYHTPSAPYVLSQRSEVLVISWEGEGPEARPASSAPGMQAPGPPPSDPGAQAPSLSSFRPRGLVLQPLLPQTQDSWDPAPPPSDPGV

Target ORF information:

RefSeq Version	NM_001282349.1
Organism	Homo sapiens(human)
Definition	Homo sapiens osteoclast associated Ig-like receptor (OSCAR), transcript variant 6, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001282349.1

ORF Insert Sequence:

ATGGCCCTGG TGCTGATCCT CCAGCTGCTG ACCCTCTGGC CTCTGTGTCA CACAGACATC 
ACTCCGTCTG TCCCCCCAGC TTCATACCAC CCTAAGCCAT GGCTGGGAGC TCAGCCGGCT 
ACAGTTGTGA CCCCTGGGGT CAACGTGACC TTGAGATGCC GGGCACCCCA ACCCGCTTGG 
AGATTTGGAC TTTTCAAGCC TGGAGAGATC GCTCCCCTTC TCTTCCGGGA TGTGTCCTCC 
GAGCTGGCAG AATTCTTTCT GGAGGAGGTG ACTCCAGCCC AAGGGGGAAG TTACCGCTGC 
TGCTACCGAA GGCCAGACTG GGGGCCGGGT GTCTGGTCCC AGCCCAGCGA TGTCCTGGAG 
CTGCTGGTGA CAGAGGAGCT GCCGCGGCCG TCGCTGGTGG CGCTGCCCGG GCCGGTGGTG 
GGTCCTGGCG CCAACGTGAG CCTGCGCTGC GCGGGCCGCC TGCGGAACAT GAGCTTCGTG 
CTGTACCGCG AGGGCGTGGC GGCCCCGCTG CAGTACCGCC ACTCCGCGCA GCCCTGGGCC 
GACTTCACGC TGCTGGGCGC CCGCGCCCCC GGCACCTACA GCTGCTACTA TCACACGCCC 
TCCGCGCCCT ACGTGCTGTC GCAGCGCAGC GAGGTGCTGG TCATCAGCTG GGAAGGTGAG 
GGCCCTGAGG CCCGGCCCGC CTCCTCCGCC CCAGGAATGC AGGCCCCAGG ACCTCCGCCC 
TCAGACCCAG GAGCCCAGGC CCCCAGCCTC TCCTCCTTCA GACCCAGGGG TCTAGTCCTG 
CAGCCCCTCC TCCCTCAGAC CCAGGATTCC TGGGACCCAG CCCCTCCTCC CTCAGATCCA 
GGAGTCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

OSCAR ( NM_001282350.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001269279.1 Homo sapiens osteoclast associated Ig-like receptor (OSCAR), transcript variant 7, mRNA.

Price & Availability↑

CloneID	OHu11518
Clone ID Related Accession (Same CDS sequence)	NM_001282350.1
Accession Version	NM_001282350.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 816bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-08-06
Organism	Homo sapiens(human)
Product	osteoclast-associated immunoglobulin-like receptor isoform 7 precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BC035023.2, AC245052.3, AF474153.1, AF251702.1 and AF391162.1. On or before Aug 31, 2013 this sequence version replaced XM_005277246.1, XM_005277297.1, XM_005278255.1, XM_005258504.1, XM_005277068.1, XM_005277095.1, XM_005277131.1, XM_005277156.1, XM_005277178.1, XM_005277201.1. Transcript Variant: This variant (7) lacks two in-frame exons in the central coding region, compared to variant 1. The encoded isoform (7) is shorter, compared to isoform 1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## CDS exon combination :: AF474153.1 [ECO:0000331] RNAseq introns :: mixed/partial sample support SAMEA2147920 [ECO:0000350] ##Evidence-Data-END## ##RefSeq-Attributes-START## CDS uses downstream in-frame AUG :: downstream AUG is associated with N-terminal localization signal (PMID:11805147) ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGGCCCTGG TGCTGATCCT CCAGCTGCTG ACCCTCTTCC CCCCAGCTTC ATACCACCCT 
AAGCCATGGC TGGGAGCTCA GCCGGCTACA GTTGTGACCC CTGGGGTCAA CGTGACCTTG 
AGATGCCGGG CACCCCAACC CGCTTGGAGA TTTGGACTTT TCAAGCCTGG AGAGATCGCT 
CCCCTTCTCT TCCGGGATGT GTCCTCCGAG CTGGCAGAAT TCTTTCTGGA GGAGGTGACT 
CCAGCCCAAG GGGGAAGTTA CCGCTGCTGC TACCGAAGGC CAGACTGGGG GCCGGGTGTC 
TGGTCCCAGC CCAGCGATGT CCTGGAGCTG CTGGTGACAG AGGAGCTGCC GCGGCCGTCG 
CTGGTGGCGC TGCCCGGGCC GGTGGTGGGT CCTGGCGCCA ACGTGAGCCT GCGCTGCGCG 
GGCCGCCTGC GGAACATGAG CTTCGTGCTG TACCGCGAGG GCGTGGCGGC CCCGCTGCAG 
TACCGCCACT CCGCGCAGCC CTGGGCCGAC TTCACGCTGC TGGGCGCCCG CGCCCCCGGC 
ACCTACAGCT GCTACTATCA CACGCCCTCC GCGCCCTACG TGCTGTCGCA GCGCAGCGAG 
GTGCTGGTCA TCAGCTGGGA AGGTGAGGGC CCTGAGGCCC GGCCCGCCTC CTCCGCCCCA 
GGAATGCAGG CCCCAGGACC TCCGCCCTCA GACCCAGGAG CCCAGGCCCC CAGCCTCTCC 
TCCTTCAGAC CCAGGGGTCT AGTCCTGCAG CCCCTCCTCC CTCAGACCCA GGATTCCTGG 
GACCCAGCCC CTCCTCCCTC AGATCCAGGA GTCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001269279.1
CDS	193..1008
Translation	MALVLILQLLTLFPPASYHPKPWLGAQPATVVTPGVNVTLRCRAPQPAWRFGLFKPGEIAPLLFRDVSSELAEFFLEEVTPAQGGSYRCCYRRPDWGPGVWSQPSDVLELLVTEELPRPSLVALPGPVVGPGANVSLRCAGRLRNMSFVLYREGVAAPLQYRHSAQPWADFTLLGARAPGTYSCYYHTPSAPYVLSQRSEVLVISWEGEGPEARPASSAPGMQAPGPPPSDPGAQAPSLSSFRPRGLVLQPLLPQTQDSWDPAPPPSDPGV

Target ORF information:

RefSeq Version	NM_001282350.1
Organism	Homo sapiens(human)
Definition	Homo sapiens osteoclast associated Ig-like receptor (OSCAR), transcript variant 7, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001282350.1

ORF Insert Sequence:

ATGGCCCTGG TGCTGATCCT CCAGCTGCTG ACCCTCTTCC CCCCAGCTTC ATACCACCCT 
AAGCCATGGC TGGGAGCTCA GCCGGCTACA GTTGTGACCC CTGGGGTCAA CGTGACCTTG 
AGATGCCGGG CACCCCAACC CGCTTGGAGA TTTGGACTTT TCAAGCCTGG AGAGATCGCT 
CCCCTTCTCT TCCGGGATGT GTCCTCCGAG CTGGCAGAAT TCTTTCTGGA GGAGGTGACT 
CCAGCCCAAG GGGGAAGTTA CCGCTGCTGC TACCGAAGGC CAGACTGGGG GCCGGGTGTC 
TGGTCCCAGC CCAGCGATGT CCTGGAGCTG CTGGTGACAG AGGAGCTGCC GCGGCCGTCG 
CTGGTGGCGC TGCCCGGGCC GGTGGTGGGT CCTGGCGCCA ACGTGAGCCT GCGCTGCGCG 
GGCCGCCTGC GGAACATGAG CTTCGTGCTG TACCGCGAGG GCGTGGCGGC CCCGCTGCAG 
TACCGCCACT CCGCGCAGCC CTGGGCCGAC TTCACGCTGC TGGGCGCCCG CGCCCCCGGC 
ACCTACAGCT GCTACTATCA CACGCCCTCC GCGCCCTACG TGCTGTCGCA GCGCAGCGAG 
GTGCTGGTCA TCAGCTGGGA AGGTGAGGGC CCTGAGGCCC GGCCCGCCTC CTCCGCCCCA 
GGAATGCAGG CCCCAGGACC TCCGCCCTCA GACCCAGGAG CCCAGGCCCC CAGCCTCTCC 
TCCTTCAGAC CCAGGGGTCT AGTCCTGCAG CCCCTCCTCC CTCAGACCCA GGATTCCTGG 
GACCCAGCCC CTCCTCCCTC AGATCCAGGA GTCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Osteoclast-Associated Receptor (OSCAR) Distribution in the Synovial Tissues of Patients with Active RA and TNF-? and RANKL Regulation of Expression by Osteoclasts In Vitro.
Inflammation40(5)1566-1575(2017 Oct)
Dharmapatni AASSK,Algate K,Coleman R,Lorimer M,Cantley MD,Smith MD,Wechalekar MD,Crotti TN

OSCAR-collagen signaling in monocytes plays a proinflammatory role and may contribute to the pathogenesis of rheumatoid arthritis.
European journal of immunology46(4)952-63(2016 Apr)
Schultz HS,Guo L,Keller P,Fleetwood AJ,Sun M,Guo W,Ma C,Hamilton JA,Bj?rkdahl O,Berchtold MW,Panina S

Structural basis for collagen recognition by the immune receptor OSCAR.
Blood127(5)529-37(2016 Feb)
Zhou L,Hinerman JM,Blaszczyk M,Miller JL,Conrady DG,Barrow AD,Chirgadze DY,Bihan D,Farndale RW,Herr AB

OSCAR is a receptor for surfactant protein D that activates TNF-? release from human CCR2+ inflammatory monocytes.
Journal of immunology (Baltimore, Md. : 1950)194(7)3317-26(2015 Apr)
Barrow AD,Palarasah Y,Bugatti M,Holehouse AS,Byers DE,Holtzman MJ,Vermi W,Skj?dt K,Crouch E,Colonna M

Levels of soluble osteoclast-associated receptor (sOSCAR) in rheumatoid arthritis: link to disease severity and cardiovascular risk.
Annals of the rheumatic diseases73(6)1276-7(2014 Jun)
Ndongo-Thiam N,de Sallmard G,Kastrup J,Miossec P

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OSCAR cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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