SPNS2 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	SPNS2
Entrez Gene ID	124976
Full Name	sphingolipid transporter 2
General protein information	Preferred Names sphingolipid transporter 2 Names protein spinster homolog 2 SPNS sphingolipid transporter 2 spinster homolog 2
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 17 Map Location: 17p13.2
Summary	The protein encoded by this gene is a transporter of sphingosine 1-phosphate, a secreted lipid that is important in cardiovascular, immunological, and neural development. Defects in this gene are a cause of early onset progressive hearing loss. [provided by RefSeq, Jul 2016].
Disorder MIM:	612584

mRNA and Protein(s)

mRNA	Protein	Name
XM_024450574.1	XP_024306342.1	protein spinster homolog 2 isoform X1
NM_001124758.1	NP_001118230.1	protein spinster homolog 2
NM_001124758.3	NP_001118230.1	protein spinster homolog 2
NM_001124758.2	NP_001118230.1	protein spinster homolog 2

Pathways from BioSystems

Homologies

Canis lupus familiaris (dog)	SPNS2	XP_005620371.1
Danio rerio (zebrafish)	spns2	NP_001077316.1
	LOC721549	XP_001117725.2
Mus musculus (house mouse)	Spns2	NP_694700.2
Gallus gallus (chicken)	SPNS2	XP_004946501.1
Homo sapiens (human)	SPNS2	NP_001118230.1
Bos taurus (cattle)	SPNS2	NP_001193083.1
Rattus norvegicus (Norway rat)	Spns2	NP_001138463.1
Xenopus tropicalis (tropical clawed frog)	spns2	NP_001120149.1

Gene Ontology
Bibliography

Related articles in PubMed

Disrupted epithelial/macrophage crosstalk via Spinster homologue 2-mediated S1P signaling may drive defective macrophage phagocytic function in COPD.
Tran HB, Jersmann H, Truong TT, Hamon R, Roscioli E, Ween M, Pitman MR, Pitson SM, Hodge G, Reynolds PN, Hodge S
PloS one12(11)e0179577(2017)

Sphingosine kinase-1, S1P transporter spinster homolog 2 and S1P2 mRNA expressions are increased in liver with advanced fibrosis in human.
Sato M, Ikeda H, Uranbileg B, Kurano M, Saigusa D, Aoki J, Maki H, Kudo H, Hasegawa K, Kokudo N, Yatomi Y
Scientific reports632119(2016 Aug)

Hyperoxia-induced p47phox activation and ROS generation is mediated through S1P transporter Spns2, and S1P/S1P1&2 signaling axis in lung endothelium.
Harijith A, Pendyala S, Ebenezer DL, Ha AW, Fu P, Wang YT, Ma K, Toth PT, Berdyshev EV, Kanteti P, Natarajan V
American journal of physiology. Lung cellular and molecular physiology311(2)L337-51(2016 Aug)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

In both macrophage and epithelial cell types, Spns2 was also found localized to cytoplasm and the nucleus, in line with a predicted bipartile Nuclear Localization Signal at the position aa282 of the human Spns2 sequence
Title: Disrupted epithelial/macrophage crosstalk via Spinster homologue 2-mediated S1P signaling may drive defective macrophage phagocytic function in COPD.

A novel role for Spns2 and S1P1&2 in the activation of p47(phox) and production of reactive oxygen species involved in hyperoxia-mediated lung injury.
Title: Hyperoxia-induced p47phox activation and ROS generation is mediated through S1P transporter Spns2, and S1P/S1P1&2 signaling axis in lung endothelium.

mammals. These findings indicate that Spns2 is required for normal maintenance of the endocochlear potential and hence for normal auditory function, and support a role for S1P signalling in hearing.
Title: Spinster homolog 2 (spns2) deficiency causes early onset progressive hearing loss.

Spns2 plays key roles in regulating the cellular functions in non-small cell lung cancer (NSCLC) cells
Title: Critical role of Spns2, a sphingosine-1-phosphate transporter, in lung cancer cell survival and migration.

Spns2 is an S1P transporter in vivo that plays a role in regulation not only of blood S1P but also lymph node and lymph S1P levels and consequently influences lymphocyte trafficking and lymphatic vessel network organization.
Title: Spns2, a transporter of phosphorylated sphingoid bases, regulates their blood and lymph levels, and the lymphatic network.

The following SPNS2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the SPNS2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu12960	NM_001124758.3 Latest version!	Homo sapiens sphingolipid transporter 2 (SPNS2), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$189.50-$265.30 $379.00
OHu104250	XM_024450574.1 Latest version!	Homo sapiens sphingolipid transporter 2 (SPNS2), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	14-16	$307.30 $439.00
View Old Accession Versions >>
OHu12960	NM_001124758.1	Homo sapiens spinster homolog 2 (Drosophila) (SPNS2), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$189.50-$265.30 $379.00
OHu12960	NM_001124758.2	Homo sapiens sphingolipid transporter 2 (SPNS2), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$189.50-$265.30 $379.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

SPNS2 ( NM_001124758.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001118230.1 Homo sapiens spinster homolog 2 (Drosophila) (SPNS2), mRNA.

Price & Availability↑

CloneID	OHu12960
Clone ID Related Accession (Same CDS sequence)	NM_001124758.1 , NM_001124758.3 , NM_001124758.2
Accession Version	NM_001124758.1	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1650bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2015-03-14
Organism	Homo sapiens(Human)
Product	protein spinster homolog 2
Comment

ATGATGTGCC TGGAATGCGC CTCGGCGGCG GCGGGCGGCG CGGAGGAGGA GGAGGCGGAC 
GCGGAGCGGC GGCGCCGGCG CCGGGGGGCG CAGCGAGGGG CTGGCGGTAG CGGTTGCTGC 
GGGGCGCGGG GCGCGGGCGG CGCTGGAGTC TCGGCCGCGG GCGATGAGGT GCAGACGCTG 
TCGGGCAGCG TAAGGCGGGC CCCGACCGGA CCCCCCGGCA CCCCCGGCAC CCCCGGCTGC 
GCAGCTACTG CAAAGGGCCC CGGCGCTCAG CAGCCCAAAC CGGCCAGCTT GGGCCGCGGG 
CGGGGGGCAG CCGCCGCCAT CCTCAGCTTG GGCAACGTGC TCAACTACCT GGACAGGTAC 
ACCGTGGCAG GCGTCCTTCT GGACATCCAG CAGCACTTTG GGGTCAAGGA CCGAGGCGCC 
GGCCTGCTGC AGTCAGTGTT CATCTGTAGC TTCATGGTGG CTGCCCCCAT CTTCGGCTAC 
CTGGGCGACC GCTTCAACAG GAAGGTGATT CTCAGCTGCG GCATTTTCTT CTGGTCGGCC 
GTCACCTTCT CCAGCTCCTT CATTCCCCAG CAGTACTTCT GGCTGCTGGT CCTGTCCCGG 
GGGCTGGTGG GCATCGGGGA GGCCAGCTAC TCCACCATCG CCCCCACTAT CATTGGCGAC 
CTCTTCACCA AGAACACGCG TACGCTCATG CTGTCCGTCT TCTACTTCGC CATCCCACTG 
GGCAGTGGCC TGGGCTACAT TACTGGCTCC AGCGTGAAGC AGGCAGCCGG AGACTGGCAC 
TGGGCATTGC GGGTGTCCCC TGTCCTGGGC ATGATCACAG GAACACTCAT CCTCATTCTG 
GTCCCAGCCA CTAAAAGGGG TCATGCCGAC CAGCTCGGGG ACCAGCTCAA GGCCCGGACC 
TCATGGCTCC GAGATATGAA GGCCCTGATT CGAAACCGCA GCTACGTCTT CTCCTCCCTG 
GCCACGTCGG CTGTCTCCTT CGCCACGGGG GCCCTGGGCA TGTGGATCCC GCTCTACCTG 
CACCGCGCCC AAGTTGTGCA GAAGACAGCA GAGACGTGCA ACAGCCCGCC CTGTGGGGCC 
AAGGACAGCC TCATCTTTGG GGCCATCACC TGCTTTACGG GATTTCTGGG CGTGGTCACG 
GGGGCAGGAG CCACGCGCTG GTGCCGCCTG AAGACCCAGC GGGCCGACCC ACTGGTGTGT 
GCCGTGGGCA TGCTGGGCTC TGCCATCTTC ATCTGCCTGA TCTTCGTGGC TGCCAAGAGC 
AGCATCGTAG GAGCCTATAT CTGTATCTTC GTCGGGGAGA CGCTGCTGTT TTCTAACTGG 
GCCATCACTG CAGACATCCT CATGTACGTG GTCATCCCCA CGCGGCGCGC CACTGCCGTG 
GCCTTGCAGA GCTTCACCTC CCACCTGCTG GGGGACGCCG GGAGCCCCTA CCTCATTGGC 
TTTATCTCAG ACCTGATCCG CCAGAGCACT AAGGACTCCC CGCTCTGGGA GTTCCTGAGC 
CTGGGCTACG CGCTCATGCT CTGCCCTTTC GTCGTGGTCC TGGGCGGCAT GTTCTTCCTC 
GCCACTGCGC TCTTCTTCGT CAGCGACCGC GCCAGGGCTG AGCAGCAGGT GAACCAGCTG 
GCGATGCCGC CCGCATCTGT GAAAGTCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq

NP_001118230.1

Translation

MMCLECASAAAGGAEEEEADAERRRRRRGAQRGAGGSGCCGARGAGGAGVSAAGDEVQTLSGSVRRAPTGPPGTPGTPGCAATAKGPGAQQPKPASLGRGRGAAAAILSLGNVLNYLDRYTVAGVLLDIQQHFGVKDRGAGLLQSVFICSFMVAAPIFGYLGDRFNRKVILSCGIFFWSAVTFSSSFIPQQYFWLLVLSRGLVGIGEASYSTIAPTIIGDLFTKNTRTLMLSVFYFAIPLGSGLGYITGSSVKQAAGDWHWALRVSPVLGMITGTLILILVPATKRGHADQLGDQLKARTSWLRDMKALIRNRSYVFSSLATSAVSFATGALGMWIPLYLHRAQVVQKTAETCNSPPCGAKDSLIFGAITCFTGFLGVVTGAGATRWCRLKTQRADPLVCAVGMLGSAIFICLIFVAAKSSIVGAYICIFVGETLLFSNWAITADILMYVVIPTRRATAVALQSFTSHLLGDAGSPYLIGFISDLIRQSTKDSPLWEFLSLGYALMLCPFVVVLGGMFFLATALFFVSDRARAEQQVNQLAMPPASVKV

Target ORF information:

RefSeq Version	NM_001124758.1
Organism	Homo sapiens(Human)
Definition	Homo sapiens spinster homolog 2 (Drosophila) (SPNS2), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001124758.1

ORF Insert Sequence:

ATGATGTGCC TGGAATGCGC CTCGGCGGCG GCGGGCGGCG CGGAGGAGGA GGAGGCGGAC 
GCGGAGCGGC GGCGCCGGCG CCGGGGGGCG CAGCGAGGGG CTGGCGGTAG CGGTTGCTGC 
GGGGCGCGGG GCGCGGGCGG CGCTGGAGTC TCGGCCGCGG GCGATGAGGT GCAGACGCTG 
TCGGGCAGCG TAAGGCGGGC CCCGACCGGA CCCCCCGGCA CCCCCGGCAC CCCCGGCTGC 
GCAGCTACTG CAAAGGGCCC CGGCGCTCAG CAGCCCAAAC CGGCCAGCTT GGGCCGCGGG 
CGGGGGGCAG CCGCCGCCAT CCTCAGCTTG GGCAACGTGC TCAACTACCT GGACAGGTAC 
ACCGTGGCAG GCGTCCTTCT GGACATCCAG CAGCACTTTG GGGTCAAGGA CCGAGGCGCC 
GGCCTGCTGC AGTCAGTGTT CATCTGTAGC TTCATGGTGG CTGCCCCCAT CTTCGGCTAC 
CTGGGCGACC GCTTCAACAG GAAGGTGATT CTCAGCTGCG GCATTTTCTT CTGGTCGGCC 
GTCACCTTCT CCAGCTCCTT CATTCCCCAG CAGTACTTCT GGCTGCTGGT CCTGTCCCGG 
GGGCTGGTGG GCATCGGGGA GGCCAGCTAC TCCACCATCG CCCCCACTAT CATTGGCGAC 
CTCTTCACCA AGAACACGCG TACGCTCATG CTGTCCGTCT TCTACTTCGC CATCCCACTG 
GGCAGTGGCC TGGGCTACAT TACTGGCTCC AGCGTGAAGC AGGCAGCCGG AGACTGGCAC 
TGGGCATTGC GGGTGTCCCC TGTCCTGGGC ATGATCACAG GAACACTCAT CCTCATTCTG 
GTCCCAGCCA CTAAAAGGGG TCATGCCGAC CAGCTCGGGG ACCAGCTCAA GGCCCGGACC 
TCATGGCTCC GAGATATGAA GGCCCTGATT CGAAACCGCA GCTACGTCTT CTCCTCCCTG 
GCCACGTCGG CTGTCTCCTT CGCCACGGGG GCCCTGGGCA TGTGGATCCC GCTCTACCTG 
CACCGCGCCC AAGTTGTGCA GAAGACAGCA GAGACGTGCA ACAGCCCGCC CTGTGGGGCC 
AAGGACAGCC TCATCTTTGG GGCCATCACC TGCTTTACGG GATTTCTGGG CGTGGTCACG 
GGGGCAGGAG CCACGCGCTG GTGCCGCCTG AAGACCCAGC GGGCCGACCC ACTGGTGTGT 
GCCGTGGGCA TGCTGGGCTC TGCCATCTTC ATCTGCCTGA TCTTCGTGGC TGCCAAGAGC 
AGCATCGTAG GAGCCTATAT CTGTATCTTC GTCGGGGAGA CGCTGCTGTT TTCTAACTGG 
GCCATCACTG CAGACATCCT CATGTACGTG GTCATCCCCA CGCGGCGCGC CACTGCCGTG 
GCCTTGCAGA GCTTCACCTC CCACCTGCTG GGGGACGCCG GGAGCCCCTA CCTCATTGGC 
TTTATCTCAG ACCTGATCCG CCAGAGCACT AAGGACTCCC CGCTCTGGGA GTTCCTGAGC 
CTGGGCTACG CGCTCATGCT CTGCCCTTTC GTCGTGGTCC TGGGCGGCAT GTTCTTCCTC 
GCCACTGCGC TCTTCTTCGT CAGCGACCGC GCCAGGGCTG AGCAGCAGGT GAACCAGCTG 
GCGATGCCGC CCGCATCTGT GAAAGTCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

SPNS2 ( NM_001124758.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_001118230.1 Homo sapiens sphingolipid transporter 2 (SPNS2), mRNA.

Price & Availability↑

CloneID	OHu12960
Clone ID Related Accession (Same CDS sequence)	NM_001124758.1 , NM_001124758.3 , NM_001124758.2
Accession Version	NM_001124758.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1650bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-06-09
Organism	Homo sapiens(human)
Product	protein spinster homolog 2
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BC041772.1, AC118754.6 and HY309474.1. On Nov 23, 2018 this sequence version replaced NM_001124758.2. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC041772.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000329078.8/ ENSP00000333292.3 RefSeq Select criteria :: based on conservation, expression ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGATGTGCC TGGAATGCGC CTCGGCGGCG GCGGGCGGCG CGGAGGAGGA GGAGGCGGAC 
GCGGAGCGGC GGCGCCGGCG CCGGGGGGCG CAGCGAGGGG CTGGCGGTAG CGGTTGCTGC 
GGGGCGCGGG GCGCGGGCGG CGCTGGAGTC TCGGCCGCGG GCGATGAGGT GCAGACGCTG 
TCGGGCAGCG TAAGGCGGGC CCCGACCGGA CCCCCCGGCA CCCCCGGCAC CCCCGGCTGC 
GCAGCTACTG CAAAGGGCCC CGGCGCTCAG CAGCCCAAAC CGGCCAGCTT GGGCCGCGGG 
CGGGGGGCAG CCGCCGCCAT CCTCAGCTTG GGCAACGTGC TCAACTACCT GGACAGGTAC 
ACCGTGGCAG GCGTCCTTCT GGACATCCAG CAGCACTTTG GGGTCAAGGA CCGAGGCGCC 
GGCCTGCTGC AGTCAGTGTT CATCTGTAGC TTCATGGTGG CTGCCCCCAT CTTCGGCTAC 
CTGGGCGACC GCTTCAACAG GAAGGTGATT CTCAGCTGCG GCATTTTCTT CTGGTCGGCC 
GTCACCTTCT CCAGCTCCTT CATTCCCCAG CAGTACTTCT GGCTGCTGGT CCTGTCCCGG 
GGGCTGGTGG GCATCGGGGA GGCCAGCTAC TCCACCATCG CCCCCACTAT CATTGGCGAC 
CTCTTCACCA AGAACACGCG TACGCTCATG CTGTCCGTCT TCTACTTCGC CATCCCACTG 
GGCAGTGGCC TGGGCTACAT TACTGGCTCC AGCGTGAAGC AGGCAGCCGG AGACTGGCAC 
TGGGCATTGC GGGTGTCCCC TGTCCTGGGC ATGATCACAG GAACACTCAT CCTCATTCTG 
GTCCCAGCCA CTAAAAGGGG TCATGCCGAC CAGCTCGGGG ACCAGCTCAA GGCCCGGACC 
TCATGGCTCC GAGATATGAA GGCCCTGATT CGAAACCGCA GCTACGTCTT CTCCTCCCTG 
GCCACGTCGG CTGTCTCCTT CGCCACGGGG GCCCTGGGCA TGTGGATCCC GCTCTACCTG 
CACCGCGCCC AAGTTGTGCA GAAGACAGCA GAGACGTGCA ACAGCCCGCC CTGTGGGGCC 
AAGGACAGCC TCATCTTTGG GGCCATCACC TGCTTTACGG GATTTCTGGG CGTGGTCACG 
GGGGCAGGAG CCACGCGCTG GTGCCGCCTG AAGACCCAGC GGGCCGACCC ACTGGTGTGT 
GCCGTGGGCA TGCTGGGCTC TGCCATCTTC ATCTGCCTGA TCTTCGTGGC TGCCAAGAGC 
AGCATCGTAG GAGCCTATAT CTGTATCTTC GTCGGGGAGA CGCTGCTGTT TTCTAACTGG 
GCCATCACTG CAGACATCCT CATGTACGTG GTCATCCCCA CGCGGCGCGC CACTGCCGTG 
GCCTTGCAGA GCTTCACCTC CCACCTGCTG GGGGACGCCG GGAGCCCCTA CCTCATTGGC 
TTTATCTCAG ACCTGATCCG CCAGAGCACT AAGGACTCCC CGCTCTGGGA GTTCCTGAGC 
CTGGGCTACG CGCTCATGCT CTGCCCTTTC GTCGTGGTCC TGGGCGGCAT GTTCTTCCTC 
GCCACTGCGC TCTTCTTCGT CAGCGACCGC GCCAGGGCTG AGCAGCAGGT GAACCAGCTG 
GCGATGCCGC CCGCATCTGT GAAAGTCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001118230.1
CDS	168..1817
Translation	MMCLECASAAAGGAEEEEADAERRRRRRGAQRGAGGSGCCGARGAGGAGVSAAGDEVQTLSGSVRRAPTGPPGTPGTPGCAATAKGPGAQQPKPASLGRGRGAAAAILSLGNVLNYLDRYTVAGVLLDIQQHFGVKDRGAGLLQSVFICSFMVAAPIFGYLGDRFNRKVILSCGIFFWSAVTFSSSFIPQQYFWLLVLSRGLVGIGEASYSTIAPTIIGDLFTKNTRTLMLSVFYFAIPLGSGLGYITGSSVKQAAGDWHWALRVSPVLGMITGTLILILVPATKRGHADQLGDQLKARTSWLRDMKALIRNRSYVFSSLATSAVSFATGALGMWIPLYLHRAQVVQKTAETCNSPPCGAKDSLIFGAITCFTGFLGVVTGAGATRWCRLKTQRADPLVCAVGMLGSAIFICLIFVAAKSSIVGAYICIFVGETLLFSNWAITADILMYVVIPTRRATAVALQSFTSHLLGDAGSPYLIGFISDLIRQSTKDSPLWEFLSLGYALMLCPFVVVLGGMFFLATALFFVSDRARAEQQVNQLAMPPASVKV

Target ORF information:

RefSeq Version	NM_001124758.3
Organism	Homo sapiens(human)
Definition	Homo sapiens sphingolipid transporter 2 (SPNS2), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001124758.3

ORF Insert Sequence:

ATGATGTGCC TGGAATGCGC CTCGGCGGCG GCGGGCGGCG CGGAGGAGGA GGAGGCGGAC 
GCGGAGCGGC GGCGCCGGCG CCGGGGGGCG CAGCGAGGGG CTGGCGGTAG CGGTTGCTGC 
GGGGCGCGGG GCGCGGGCGG CGCTGGAGTC TCGGCCGCGG GCGATGAGGT GCAGACGCTG 
TCGGGCAGCG TAAGGCGGGC CCCGACCGGA CCCCCCGGCA CCCCCGGCAC CCCCGGCTGC 
GCAGCTACTG CAAAGGGCCC CGGCGCTCAG CAGCCCAAAC CGGCCAGCTT GGGCCGCGGG 
CGGGGGGCAG CCGCCGCCAT CCTCAGCTTG GGCAACGTGC TCAACTACCT GGACAGGTAC 
ACCGTGGCAG GCGTCCTTCT GGACATCCAG CAGCACTTTG GGGTCAAGGA CCGAGGCGCC 
GGCCTGCTGC AGTCAGTGTT CATCTGTAGC TTCATGGTGG CTGCCCCCAT CTTCGGCTAC 
CTGGGCGACC GCTTCAACAG GAAGGTGATT CTCAGCTGCG GCATTTTCTT CTGGTCGGCC 
GTCACCTTCT CCAGCTCCTT CATTCCCCAG CAGTACTTCT GGCTGCTGGT CCTGTCCCGG 
GGGCTGGTGG GCATCGGGGA GGCCAGCTAC TCCACCATCG CCCCCACTAT CATTGGCGAC 
CTCTTCACCA AGAACACGCG TACGCTCATG CTGTCCGTCT TCTACTTCGC CATCCCACTG 
GGCAGTGGCC TGGGCTACAT TACTGGCTCC AGCGTGAAGC AGGCAGCCGG AGACTGGCAC 
TGGGCATTGC GGGTGTCCCC TGTCCTGGGC ATGATCACAG GAACACTCAT CCTCATTCTG 
GTCCCAGCCA CTAAAAGGGG TCATGCCGAC CAGCTCGGGG ACCAGCTCAA GGCCCGGACC 
TCATGGCTCC GAGATATGAA GGCCCTGATT CGAAACCGCA GCTACGTCTT CTCCTCCCTG 
GCCACGTCGG CTGTCTCCTT CGCCACGGGG GCCCTGGGCA TGTGGATCCC GCTCTACCTG 
CACCGCGCCC AAGTTGTGCA GAAGACAGCA GAGACGTGCA ACAGCCCGCC CTGTGGGGCC 
AAGGACAGCC TCATCTTTGG GGCCATCACC TGCTTTACGG GATTTCTGGG CGTGGTCACG 
GGGGCAGGAG CCACGCGCTG GTGCCGCCTG AAGACCCAGC GGGCCGACCC ACTGGTGTGT 
GCCGTGGGCA TGCTGGGCTC TGCCATCTTC ATCTGCCTGA TCTTCGTGGC TGCCAAGAGC 
AGCATCGTAG GAGCCTATAT CTGTATCTTC GTCGGGGAGA CGCTGCTGTT TTCTAACTGG 
GCCATCACTG CAGACATCCT CATGTACGTG GTCATCCCCA CGCGGCGCGC CACTGCCGTG 
GCCTTGCAGA GCTTCACCTC CCACCTGCTG GGGGACGCCG GGAGCCCCTA CCTCATTGGC 
TTTATCTCAG ACCTGATCCG CCAGAGCACT AAGGACTCCC CGCTCTGGGA GTTCCTGAGC 
CTGGGCTACG CGCTCATGCT CTGCCCTTTC GTCGTGGTCC TGGGCGGCAT GTTCTTCCTC 
GCCACTGCGC TCTTCTTCGT CAGCGACCGC GCCAGGGCTG AGCAGCAGGT GAACCAGCTG 
GCGATGCCGC CCGCATCTGT GAAAGTCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

SPNS2 ( NM_001124758.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_001118230.1 Homo sapiens sphingolipid transporter 2 (SPNS2), mRNA.

Price & Availability↑

CloneID	OHu12960
Clone ID Related Accession (Same CDS sequence)	NM_001124758.1 , NM_001124758.3 , NM_001124758.2
Accession Version	NM_001124758.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1650bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-12-05
Organism	Homo sapiens(human)
Product	protein spinster homolog 2
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BC041772.1, AC118754.6 and HY309474.1. On Jul 9, 2016 this sequence version replaced NM_001124758.1. ##Evidence-Data-START## Transcript exon combination :: BC041772.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGATGTGCC TGGAATGCGC CTCGGCGGCG GCGGGCGGCG CGGAGGAGGA GGAGGCGGAC 
GCGGAGCGGC GGCGCCGGCG CCGGGGGGCG CAGCGAGGGG CTGGCGGTAG CGGTTGCTGC 
GGGGCGCGGG GCGCGGGCGG CGCTGGAGTC TCGGCCGCGG GCGATGAGGT GCAGACGCTG 
TCGGGCAGCG TAAGGCGGGC CCCGACCGGA CCCCCCGGCA CCCCCGGCAC CCCCGGCTGC 
GCAGCTACTG CAAAGGGCCC CGGCGCTCAG CAGCCCAAAC CGGCCAGCTT GGGCCGCGGG 
CGGGGGGCAG CCGCCGCCAT CCTCAGCTTG GGCAACGTGC TCAACTACCT GGACAGGTAC 
ACCGTGGCAG GCGTCCTTCT GGACATCCAG CAGCACTTTG GGGTCAAGGA CCGAGGCGCC 
GGCCTGCTGC AGTCAGTGTT CATCTGTAGC TTCATGGTGG CTGCCCCCAT CTTCGGCTAC 
CTGGGCGACC GCTTCAACAG GAAGGTGATT CTCAGCTGCG GCATTTTCTT CTGGTCGGCC 
GTCACCTTCT CCAGCTCCTT CATTCCCCAG CAGTACTTCT GGCTGCTGGT CCTGTCCCGG 
GGGCTGGTGG GCATCGGGGA GGCCAGCTAC TCCACCATCG CCCCCACTAT CATTGGCGAC 
CTCTTCACCA AGAACACGCG TACGCTCATG CTGTCCGTCT TCTACTTCGC CATCCCACTG 
GGCAGTGGCC TGGGCTACAT TACTGGCTCC AGCGTGAAGC AGGCAGCCGG AGACTGGCAC 
TGGGCATTGC GGGTGTCCCC TGTCCTGGGC ATGATCACAG GAACACTCAT CCTCATTCTG 
GTCCCAGCCA CTAAAAGGGG TCATGCCGAC CAGCTCGGGG ACCAGCTCAA GGCCCGGACC 
TCATGGCTCC GAGATATGAA GGCCCTGATT CGAAACCGCA GCTACGTCTT CTCCTCCCTG 
GCCACGTCGG CTGTCTCCTT CGCCACGGGG GCCCTGGGCA TGTGGATCCC GCTCTACCTG 
CACCGCGCCC AAGTTGTGCA GAAGACAGCA GAGACGTGCA ACAGCCCGCC CTGTGGGGCC 
AAGGACAGCC TCATCTTTGG GGCCATCACC TGCTTTACGG GATTTCTGGG CGTGGTCACG 
GGGGCAGGAG CCACGCGCTG GTGCCGCCTG AAGACCCAGC GGGCCGACCC ACTGGTGTGT 
GCCGTGGGCA TGCTGGGCTC TGCCATCTTC ATCTGCCTGA TCTTCGTGGC TGCCAAGAGC 
AGCATCGTAG GAGCCTATAT CTGTATCTTC GTCGGGGAGA CGCTGCTGTT TTCTAACTGG 
GCCATCACTG CAGACATCCT CATGTACGTG GTCATCCCCA CGCGGCGCGC CACTGCCGTG 
GCCTTGCAGA GCTTCACCTC CCACCTGCTG GGGGACGCCG GGAGCCCCTA CCTCATTGGC 
TTTATCTCAG ACCTGATCCG CCAGAGCACT AAGGACTCCC CGCTCTGGGA GTTCCTGAGC 
CTGGGCTACG CGCTCATGCT CTGCCCTTTC GTCGTGGTCC TGGGCGGCAT GTTCTTCCTC 
GCCACTGCGC TCTTCTTCGT CAGCGACCGC GCCAGGGCTG AGCAGCAGGT GAACCAGCTG 
GCGATGCCGC CCGCATCTGT GAAAGTCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001118230.1
CDS	206..1855
Translation	MMCLECASAAAGGAEEEEADAERRRRRRGAQRGAGGSGCCGARGAGGAGVSAAGDEVQTLSGSVRRAPTGPPGTPGTPGCAATAKGPGAQQPKPASLGRGRGAAAAILSLGNVLNYLDRYTVAGVLLDIQQHFGVKDRGAGLLQSVFICSFMVAAPIFGYLGDRFNRKVILSCGIFFWSAVTFSSSFIPQQYFWLLVLSRGLVGIGEASYSTIAPTIIGDLFTKNTRTLMLSVFYFAIPLGSGLGYITGSSVKQAAGDWHWALRVSPVLGMITGTLILILVPATKRGHADQLGDQLKARTSWLRDMKALIRNRSYVFSSLATSAVSFATGALGMWIPLYLHRAQVVQKTAETCNSPPCGAKDSLIFGAITCFTGFLGVVTGAGATRWCRLKTQRADPLVCAVGMLGSAIFICLIFVAAKSSIVGAYICIFVGETLLFSNWAITADILMYVVIPTRRATAVALQSFTSHLLGDAGSPYLIGFISDLIRQSTKDSPLWEFLSLGYALMLCPFVVVLGGMFFLATALFFVSDRARAEQQVNQLAMPPASVKV

Target ORF information:

RefSeq Version	NM_001124758.2
Organism	Homo sapiens(human)
Definition	Homo sapiens sphingolipid transporter 2 (SPNS2), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001124758.2

ORF Insert Sequence:

ATGATGTGCC TGGAATGCGC CTCGGCGGCG GCGGGCGGCG CGGAGGAGGA GGAGGCGGAC 
GCGGAGCGGC GGCGCCGGCG CCGGGGGGCG CAGCGAGGGG CTGGCGGTAG CGGTTGCTGC 
GGGGCGCGGG GCGCGGGCGG CGCTGGAGTC TCGGCCGCGG GCGATGAGGT GCAGACGCTG 
TCGGGCAGCG TAAGGCGGGC CCCGACCGGA CCCCCCGGCA CCCCCGGCAC CCCCGGCTGC 
GCAGCTACTG CAAAGGGCCC CGGCGCTCAG CAGCCCAAAC CGGCCAGCTT GGGCCGCGGG 
CGGGGGGCAG CCGCCGCCAT CCTCAGCTTG GGCAACGTGC TCAACTACCT GGACAGGTAC 
ACCGTGGCAG GCGTCCTTCT GGACATCCAG CAGCACTTTG GGGTCAAGGA CCGAGGCGCC 
GGCCTGCTGC AGTCAGTGTT CATCTGTAGC TTCATGGTGG CTGCCCCCAT CTTCGGCTAC 
CTGGGCGACC GCTTCAACAG GAAGGTGATT CTCAGCTGCG GCATTTTCTT CTGGTCGGCC 
GTCACCTTCT CCAGCTCCTT CATTCCCCAG CAGTACTTCT GGCTGCTGGT CCTGTCCCGG 
GGGCTGGTGG GCATCGGGGA GGCCAGCTAC TCCACCATCG CCCCCACTAT CATTGGCGAC 
CTCTTCACCA AGAACACGCG TACGCTCATG CTGTCCGTCT TCTACTTCGC CATCCCACTG 
GGCAGTGGCC TGGGCTACAT TACTGGCTCC AGCGTGAAGC AGGCAGCCGG AGACTGGCAC 
TGGGCATTGC GGGTGTCCCC TGTCCTGGGC ATGATCACAG GAACACTCAT CCTCATTCTG 
GTCCCAGCCA CTAAAAGGGG TCATGCCGAC CAGCTCGGGG ACCAGCTCAA GGCCCGGACC 
TCATGGCTCC GAGATATGAA GGCCCTGATT CGAAACCGCA GCTACGTCTT CTCCTCCCTG 
GCCACGTCGG CTGTCTCCTT CGCCACGGGG GCCCTGGGCA TGTGGATCCC GCTCTACCTG 
CACCGCGCCC AAGTTGTGCA GAAGACAGCA GAGACGTGCA ACAGCCCGCC CTGTGGGGCC 
AAGGACAGCC TCATCTTTGG GGCCATCACC TGCTTTACGG GATTTCTGGG CGTGGTCACG 
GGGGCAGGAG CCACGCGCTG GTGCCGCCTG AAGACCCAGC GGGCCGACCC ACTGGTGTGT 
GCCGTGGGCA TGCTGGGCTC TGCCATCTTC ATCTGCCTGA TCTTCGTGGC TGCCAAGAGC 
AGCATCGTAG GAGCCTATAT CTGTATCTTC GTCGGGGAGA CGCTGCTGTT TTCTAACTGG 
GCCATCACTG CAGACATCCT CATGTACGTG GTCATCCCCA CGCGGCGCGC CACTGCCGTG 
GCCTTGCAGA GCTTCACCTC CCACCTGCTG GGGGACGCCG GGAGCCCCTA CCTCATTGGC 
TTTATCTCAG ACCTGATCCG CCAGAGCACT AAGGACTCCC CGCTCTGGGA GTTCCTGAGC 
CTGGGCTACG CGCTCATGCT CTGCCCTTTC GTCGTGGTCC TGGGCGGCAT GTTCTTCCTC 
GCCACTGCGC TCTTCTTCGT CAGCGACCGC GCCAGGGCTG AGCAGCAGGT GAACCAGCTG 
GCGATGCCGC CCGCATCTGT GAAAGTCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

SPNS2 ( XM_024450574.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_024306342.1 Homo sapiens sphingolipid transporter 2 (SPNS2), transcript variant X1, mRNA.

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CloneID	OHu104250
Clone ID Related Accession (Same CDS sequence)	XM_024450574.1
Accession Version	XM_024450574.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1686bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	protein spinster homolog 2 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000017.11) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGATGTGCC TGGAATGCGC CTCGGCGGCG GCGGGCGGCG CGGAGGAGGA GGAGGCGGAC 
GCGGAGCGGC GGCGCCGGCG CCGGGGGGCG CAGCGAGGGG CTGGCGGTAG CGGTTGCTGC 
GGGGCGCGGG GCGCGGGCGG CGCTGGAGTC TCGGCCGCGG GCGATGAGGT GCAGACGCTG 
TCGGGCAGCG TAAGGCGGGC CCCGACCGGA CCCCCCGGCA CCCCCGGCAC CCCCGGCTGC 
GCAGCTACTG CAAAGGGCCC CGGCGCTCAG CAGCCCAAAC CGGCCAGCTT GGGCCGCGGG 
CGGGGGGCAG CCGCCGCCAT CCTCAGCTTG GGCAACGTGC TCAACTACCT GGACAGGTAC 
ACCGTGGCAG GCGTCCTTCT GGACATCCAG CAGCACTTTG GGGTCAAGGA CCGAGGCGCC 
GGCCTGCTGC AGTCAGTGTT CATCTGTAGC TTCATGGTGG CTGCCCCCAT CTTCGGCTAC 
CTGGGCGACC GCTTCAACAG GAAGGTGATT CTCAGCTGCG GCATTTTCTT CTGGTCGGCC 
GTCACCTTCT CCAGCTCCTT CATTCCCCAG CAGTACTTCT GGCTGCTGGT CCTGTCCCGG 
GGGCTGGTGG GCATCGGGGA GGCCAGCTAC TCCACCATCG CCCCCACTAT CATTGGCGAC 
CTCTTCACCA AGAACACGCG TACGCTCATG CTGTCCGTCT TCTACTTCGC CATCCCACTG 
GGCAGTGGCC TGGGCTACAT TACTGGCTCC AGCGTGAAGC AGGCAGCCGG AGACTGGCAC 
TGGGCATTGC GGGTGTCCCC TGTCCTGGGC ATGATCACAG GAACACTCAT CCTCATTCTG 
GTCCCAGCCA CTAAAAGGGG TCATGCCGAC CAGCTCGGGG ACCAGCTCAA GGCCCGGACC 
TCATGGCTCC GAGATATGAA GGCCCTGATT CGAAACCGCA GCTACGTCTT CTCCTCCCTG 
GCCACGTCGG CTGTCTCCTT CGCCACGGGG GCCCTGGGCA TGTGGATCCC GCTCTACCTG 
CACCGCGCCC AAGTTGTGCA GAAGACAGCA GAGACGTGCA ACAGCCCGCC CTGTGGGGCC 
AAGGACAGCC TCATCTTTGG GGCCATCACC TGCTTTACGG GATTTCTGGG CGTGGTCACG 
GGGGCAGGAG CCACGCGCTG GTGCCGCCTG AAGACCCAGC GGGCCGACCC ACTGGTGTGT 
GCCGTGGGCA TGCTGGGCTC TGCCATCTTC ATCTGCCTGA TCTTCGTGGC TGCCAAGAGC 
AGCATCGTAG GAGCCTATAT CTGTATCTTC GTCGGGGAGA CGCTGCTGTT TTCTAACTGG 
GCCATCACTG CAGACATCCT CATGTACGTG GTCATCCCCA CGCGGCGCGC CACTGCCGTG 
GCCTTGCAGA GCTTCACCTC CCACCTGCTG GGGGACGCCG GGAGCCCCTA CCTCATTGGC 
TTTATCTCAG ACCTGATCCG CCAGAGCACT AAGGACTCCC CGCTCTGGGA GTTCCTGAGC 
CTGGGCTACG CGCTCATGCT CTGCCCTTTC GTCGTGGTCC TGGGCGGCAT GTTCTTCCTC 
GCCACTGCGC TCTTCTTCGT CAGCGACCGC GCCAGGGCTG AGCAGCAGTC CCTGCCCAGC 
ACCTCCGGTC AGCTGGCCCC CACGACACGA TGTGCCAGAG CAGTGCCCGG GCCCGGCCCC 
CGCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_024306342.1
CDS	160..1845
Translation	MMCLECASAAAGGAEEEEADAERRRRRRGAQRGAGGSGCCGARGAGGAGVSAAGDEVQTLSGSVRRAPTGPPGTPGTPGCAATAKGPGAQQPKPASLGRGRGAAAAILSLGNVLNYLDRYTVAGVLLDIQQHFGVKDRGAGLLQSVFICSFMVAAPIFGYLGDRFNRKVILSCGIFFWSAVTFSSSFIPQQYFWLLVLSRGLVGIGEASYSTIAPTIIGDLFTKNTRTLMLSVFYFAIPLGSGLGYITGSSVKQAAGDWHWALRVSPVLGMITGTLILILVPATKRGHADQLGDQLKARTSWLRDMKALIRNRSYVFSSLATSAVSFATGALGMWIPLYLHRAQVVQKTAETCNSPPCGAKDSLIFGAITCFTGFLGVVTGAGATRWCRLKTQRADPLVCAVGMLGSAIFICLIFVAAKSSIVGAYICIFVGETLLFSNWAITADILMYVVIPTRRATAVALQSFTSHLLGDAGSPYLIGFISDLIRQSTKDSPLWEFLSLGYALMLCPFVVVLGGMFFLATALFFVSDRARAEQQSLPSTSGQLAPTTRCARAVPGPGPR

Target ORF information:

RefSeq Version	XM_024450574.1
Organism	Homo sapiens(human)
Definition	Homo sapiens sphingolipid transporter 2 (SPNS2), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_024450574.1

ORF Insert Sequence:

ATGATGTGCC TGGAATGCGC CTCGGCGGCG GCGGGCGGCG CGGAGGAGGA GGAGGCGGAC 
GCGGAGCGGC GGCGCCGGCG CCGGGGGGCG CAGCGAGGGG CTGGCGGTAG CGGTTGCTGC 
GGGGCGCGGG GCGCGGGCGG CGCTGGAGTC TCGGCCGCGG GCGATGAGGT GCAGACGCTG 
TCGGGCAGCG TAAGGCGGGC CCCGACCGGA CCCCCCGGCA CCCCCGGCAC CCCCGGCTGC 
GCAGCTACTG CAAAGGGCCC CGGCGCTCAG CAGCCCAAAC CGGCCAGCTT GGGCCGCGGG 
CGGGGGGCAG CCGCCGCCAT CCTCAGCTTG GGCAACGTGC TCAACTACCT GGACAGGTAC 
ACCGTGGCAG GCGTCCTTCT GGACATCCAG CAGCACTTTG GGGTCAAGGA CCGAGGCGCC 
GGCCTGCTGC AGTCAGTGTT CATCTGTAGC TTCATGGTGG CTGCCCCCAT CTTCGGCTAC 
CTGGGCGACC GCTTCAACAG GAAGGTGATT CTCAGCTGCG GCATTTTCTT CTGGTCGGCC 
GTCACCTTCT CCAGCTCCTT CATTCCCCAG CAGTACTTCT GGCTGCTGGT CCTGTCCCGG 
GGGCTGGTGG GCATCGGGGA GGCCAGCTAC TCCACCATCG CCCCCACTAT CATTGGCGAC 
CTCTTCACCA AGAACACGCG TACGCTCATG CTGTCCGTCT TCTACTTCGC CATCCCACTG 
GGCAGTGGCC TGGGCTACAT TACTGGCTCC AGCGTGAAGC AGGCAGCCGG AGACTGGCAC 
TGGGCATTGC GGGTGTCCCC TGTCCTGGGC ATGATCACAG GAACACTCAT CCTCATTCTG 
GTCCCAGCCA CTAAAAGGGG TCATGCCGAC CAGCTCGGGG ACCAGCTCAA GGCCCGGACC 
TCATGGCTCC GAGATATGAA GGCCCTGATT CGAAACCGCA GCTACGTCTT CTCCTCCCTG 
GCCACGTCGG CTGTCTCCTT CGCCACGGGG GCCCTGGGCA TGTGGATCCC GCTCTACCTG 
CACCGCGCCC AAGTTGTGCA GAAGACAGCA GAGACGTGCA ACAGCCCGCC CTGTGGGGCC 
AAGGACAGCC TCATCTTTGG GGCCATCACC TGCTTTACGG GATTTCTGGG CGTGGTCACG 
GGGGCAGGAG CCACGCGCTG GTGCCGCCTG AAGACCCAGC GGGCCGACCC ACTGGTGTGT 
GCCGTGGGCA TGCTGGGCTC TGCCATCTTC ATCTGCCTGA TCTTCGTGGC TGCCAAGAGC 
AGCATCGTAG GAGCCTATAT CTGTATCTTC GTCGGGGAGA CGCTGCTGTT TTCTAACTGG 
GCCATCACTG CAGACATCCT CATGTACGTG GTCATCCCCA CGCGGCGCGC CACTGCCGTG 
GCCTTGCAGA GCTTCACCTC CCACCTGCTG GGGGACGCCG GGAGCCCCTA CCTCATTGGC 
TTTATCTCAG ACCTGATCCG CCAGAGCACT AAGGACTCCC CGCTCTGGGA GTTCCTGAGC 
CTGGGCTACG CGCTCATGCT CTGCCCTTTC GTCGTGGTCC TGGGCGGCAT GTTCTTCCTC 
GCCACTGCGC TCTTCTTCGT CAGCGACCGC GCCAGGGCTG AGCAGCAGTC CCTGCCCAGC 
ACCTCCGGTC AGCTGGCCCC CACGACACGA TGTGCCAGAG CAGTGCCCGG GCCCGGCCCC 
CGCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Disrupted epithelial/macrophage crosstalk via Spinster homologue 2-mediated S1P signaling may drive defective macrophage phagocytic function in COPD.
PloS one12(11)e0179577(2017)
Tran HB,Jersmann H,Truong TT,Hamon R,Roscioli E,Ween M,Pitman MR,Pitson SM,Hodge G,Reynolds PN,Hodge S

Sphingosine kinase-1, S1P transporter spinster homolog 2 and S1P2 mRNA expressions are increased in liver with advanced fibrosis in human.
Scientific reports632119(2016 Aug)
Sato M,Ikeda H,Uranbileg B,Kurano M,Saigusa D,Aoki J,Maki H,Kudo H,Hasegawa K,Kokudo N,Yatomi Y

Hyperoxia-induced p47phox activation and ROS generation is mediated through S1P transporter Spns2, and S1P/S1P1&2 signaling axis in lung endothelium.
American journal of physiology. Lung cellular and molecular physiology311(2)L337-51(2016 Aug)
Harijith A,Pendyala S,Ebenezer DL,Ha AW,Fu P,Wang YT,Ma K,Toth PT,Berdyshev EV,Kanteti P,Natarajan V

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SPNS2 cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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