IQCK cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	IQCK
Entrez Gene ID	124152
Full Name	IQ motif containing K
General protein information	Preferred Names IQ motif containing K Names IQ domain-containing protein K
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 16 Map Location: 16p12.3
Summary	This gene belongs to the IQ motif-containing family of proteins. The IQ motif serves as a binding site for different EF-hand proteins such as calmodulin. This gene was identified as a potential candidate gene for obsessive-compulsive disorder in a genome-wide association study. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Feb 2015].

mRNA and Protein(s)

mRNA	Protein	Name
NM_001305121.1	NP_001292050.1	IQ domain-containing protein K isoform 2
XM_011545736.2	XP_011544038.1	IQ domain-containing protein K isoform X2
XM_011545736.3	XP_011544038.1	IQ domain-containing protein K isoform X1
XM_017022933.1	XP_016878422.1	IQ domain-containing protein K isoform X1
NM_001305122.1	NP_001292051.1	IQ domain-containing protein K isoform 3
NM_153208.2	NP_694940.1	IQ domain-containing protein K isoform 1

Pathways from BioSystems

Homologies

Canis lupus familiaris (dog)	IQCK	XP_003639154.1
Homo sapiens (human)	IQCK	NP_694940.1
Mus musculus (house mouse)	Iqck	NP_001074915.1
Xenopus tropicalis (tropical clawed frog)	iqck	XP_002932259.2
Pan troglodytes (chimpanzee)	IQCK	NP_001233405.1
	IQCK	XP_001084890.1
Rattus norvegicus (Norway rat)	Iqck	XP_006230211.1
Bos taurus (cattle)	IQCK	NP_001179017.1
Gallus gallus (chicken)	IQCK	XP_424597.4

Gene Ontology
Bibliography

Related articles in PubMed

Genome-wide association study in obsessive-compulsive disorder: results from the OCGAS.
Mattheisen M, Samuels JF, Wang Y, Greenberg BD, Fyer AJ, McCracken JT, Geller DA, Murphy DL, Knowles JA, Grados MA, Riddle MA, Rasmussen SA, McLaughlin NC, Nurmi EL, Askland KD, Qin HD, Cullen BA, Piacentini J, Pauls DL, Bienvenu OJ, Stewart SE, Liang KY, Goes FS, Maher B, Pulver AE, Shugart YY, Valle D, Lange C, Nestadt G
Molecular psychiatry20(3)337-44(2015 Mar)

Genetic variation at the CELF1 (CUGBP, elav-like family member 1 gene) locus is genome-wide associated with Alzheimer's disease and obesity.
Hinney A, Albayrak O, Antel J, Volckmar AL, Sims R, Chapman J, Harold D, Gerrish A, Heid IM, Winkler TW, Scherag A, Wiltfang J, Williams J, Hebebrand J, , ,
American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics165B(4)283-93(2014 Jun)

Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study.
Bailey SD, Xie C, Do R, Montpetit A, Diaz R, Mohan V, Keavney B, Yusuf S, Gerstein HC, Engert JC, Anand S,
Diabetes care33(10)2250-3(2010 Oct)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Observational study of gene-disease association, gene-environment interaction, and pharmacogenomic / toxicogenomic. (HuGE Navigator)
Title: Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study.

Observational study of gene-disease association. (HuGE Navigator)
Title: Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip.

The following IQCK gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the IQCK cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu30777	NM_153208.2 Latest version!	Homo sapiens IQ motif containing K (IQCK), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$99.50-$139.30 $199.00
OHu30777	XM_017022933.1 Latest version!	Homo sapiens IQ motif containing K (IQCK), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$99.50-$139.30 $199.00
OHu75283	NM_001305121.1 Latest version!	Homo sapiens IQ motif containing K (IQCK), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$69.30 $99.00
OHu75283	XM_011545736.3 Latest version!	Homo sapiens IQ motif containing K (IQCK), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$69.30 $99.00
OHu75284	NM_001305122.1 Latest version!	Homo sapiens IQ motif containing K (IQCK), transcript variant 3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$139.30 $199.00
View Old Accession Versions >>
OHu75283	XM_011545736.2	Homo sapiens IQ motif containing K (IQCK), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$69.30 $99.00
Hide Old Accession Versions >>

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***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

IQCK ( NM_153208.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_694940.1 Homo sapiens IQ motif containing K (IQCK), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu30777
Clone ID Related Accession (Same CDS sequence)	XM_017022933.1 , NM_153208.2
Accession Version	NM_153208.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 864bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-04-30
Organism	Homo sapiens(human)
Product	IQ domain-containing protein K isoform 1
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AF520570.1, AC134300.3 and AW138537.1. On Feb 25, 2015 this sequence version replaced NM_153208.1. Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (1). Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. ##Evidence-Data-START## Transcript exon combination :: AF520570.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968540, SAMEA2145893 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## RefSeq Select criteria :: based on conservation, expression, longest protein ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGGCGGCAC CGCGGCAAAT CCCCAGCCAC ATAGTGCGCC TCAAGCCCAG CTGCTCTACA 
GACTCGTCGT TCACCCGGAC GCCGGTGCCC ACCGTGTCTC TCGCGTCCCG CGAGCTGCCT 
GTCTCGTCGT GGCAGGTCAC CGAGCCGTCA AGCAAGAATC TGTGGGAGCA GATCTGCAAG 
GAGTATGAAG CTGAGCAGCC TCCCTTTCCA GAAGGATATA AAGTCAAACA GGAGCCTGTG 
ATTACGGTTG CGCCAGTAGA GGAAATGCTT TTTCATGGCT TCAGTGCAGA GCACTATTTT 
CCGGTTTCCC ATTTCACCAT GATCTCACGT ACACCCTGTC CTCAAGATAA ATCGGAAACA 
ATCAACCCAA AAACATGTTC TCCCAAAGAA TATTTGGAAA CTTTCATCTT TCCTGTTCTG 
CTTCCCGGAA TGGCTAGCCT GCTTCACCAA GCGAAGAAAG AAAAATGTTT TGAGAGGAAA 
AGAACCAAAT TCATTGCCTG TGATTTTCTG ACTGAGTGGT TATACAACCA AAATCCAAAG 
AGGGCAGGGG AGCCATTCAC AGAATTTTTC TCCATTCCAT TTGTGGAGGA GCGGCTAAAG 
CAACACCCAC GGCCGCCAAT CCCACTCTCG CTCCTGCTGA CAGAAGAGGA AGCAGCCCTC 
TACATTCAAT CCTTCTGGAG AGCCTGTGTG GTTCGCTGTG ATCCTGAGAT TCAAGAACTG 
CGTCAGTGGC AGAAGAAACT TCGCGAGGCC AAGCACATTC ACCAGCAAGT CAAAATTTTC 
TGGGCCAAGC AAGAACAAAA AGTGAAATGC AAAATGGAGG ACGATGCAGT ACCTGCAGCC 
AAGATGAAAA TTCCATCATC TTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_694940.1
CDS	700..1563
Translation	MAAPRQIPSHIVRLKPSCSTDSSFTRTPVPTVSLASRELPVSSWQVTEPSSKNLWEQICKEYEAEQPPFPEGYKVKQEPVITVAPVEEMLFHGFSAEHYFPVSHFTMISRTPCPQDKSETINPKTCSPKEYLETFIFPVLLPGMASLLHQAKKEKCFERKRTKFIACDFLTEWLYNQNPKRAGEPFTEFFSIPFVEERLKQHPRPPIPLSLLLTEEEAALYIQSFWRACVVRCDPEIQELRQWQKKLREAKHIHQQVKIFWAKQEQKVKCKMEDDAVPAAKMKIPSS

Target ORF information:

RefSeq Version	NM_153208.2
Organism	Homo sapiens(human)
Definition	Homo sapiens IQ motif containing K (IQCK), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_153208.2

ORF Insert Sequence:

ATGGCGGCAC CGCGGCAAAT CCCCAGCCAC ATAGTGCGCC TCAAGCCCAG CTGCTCTACA 
GACTCGTCGT TCACCCGGAC GCCGGTGCCC ACCGTGTCTC TCGCGTCCCG CGAGCTGCCT 
GTCTCGTCGT GGCAGGTCAC CGAGCCGTCA AGCAAGAATC TGTGGGAGCA GATCTGCAAG 
GAGTATGAAG CTGAGCAGCC TCCCTTTCCA GAAGGATATA AAGTCAAACA GGAGCCTGTG 
ATTACGGTTG CGCCAGTAGA GGAAATGCTT TTTCATGGCT TCAGTGCAGA GCACTATTTT 
CCGGTTTCCC ATTTCACCAT GATCTCACGT ACACCCTGTC CTCAAGATAA ATCGGAAACA 
ATCAACCCAA AAACATGTTC TCCCAAAGAA TATTTGGAAA CTTTCATCTT TCCTGTTCTG 
CTTCCCGGAA TGGCTAGCCT GCTTCACCAA GCGAAGAAAG AAAAATGTTT TGAGAGGAAA 
AGAACCAAAT TCATTGCCTG TGATTTTCTG ACTGAGTGGT TATACAACCA AAATCCAAAG 
AGGGCAGGGG AGCCATTCAC AGAATTTTTC TCCATTCCAT TTGTGGAGGA GCGGCTAAAG 
CAACACCCAC GGCCGCCAAT CCCACTCTCG CTCCTGCTGA CAGAAGAGGA AGCAGCCCTC 
TACATTCAAT CCTTCTGGAG AGCCTGTGTG GTTCGCTGTG ATCCTGAGAT TCAAGAACTG 
CGTCAGTGGC AGAAGAAACT TCGCGAGGCC AAGCACATTC ACCAGCAAGT CAAAATTTTC 
TGGGCCAAGC AAGAACAAAA AGTGAAATGC AAAATGGAGG ACGATGCAGT ACCTGCAGCC 
AAGATGAAAA TTCCATCATC TTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

IQCK ( XM_017022933.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_016878422.1 Homo sapiens IQ motif containing K (IQCK), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OHu30777
Clone ID Related Accession (Same CDS sequence)	XM_017022933.1 , NM_153208.2
Accession Version	XM_017022933.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 864bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-06-05
Organism	Homo sapiens(human)
Product	IQ domain-containing protein K isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000016.10) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGCGGCAC CGCGGCAAAT CCCCAGCCAC ATAGTGCGCC TCAAGCCCAG CTGCTCTACA 
GACTCGTCGT TCACCCGGAC GCCGGTGCCC ACCGTGTCTC TCGCGTCCCG CGAGCTGCCT 
GTCTCGTCGT GGCAGGTCAC CGAGCCGTCA AGCAAGAATC TGTGGGAGCA GATCTGCAAG 
GAGTATGAAG CTGAGCAGCC TCCCTTTCCA GAAGGATATA AAGTCAAACA GGAGCCTGTG 
ATTACGGTTG CGCCAGTAGA GGAAATGCTT TTTCATGGCT TCAGTGCAGA GCACTATTTT 
CCGGTTTCCC ATTTCACCAT GATCTCACGT ACACCCTGTC CTCAAGATAA ATCGGAAACA 
ATCAACCCAA AAACATGTTC TCCCAAAGAA TATTTGGAAA CTTTCATCTT TCCTGTTCTG 
CTTCCCGGAA TGGCTAGCCT GCTTCACCAA GCGAAGAAAG AAAAATGTTT TGAGAGGAAA 
AGAACCAAAT TCATTGCCTG TGATTTTCTG ACTGAGTGGT TATACAACCA AAATCCAAAG 
AGGGCAGGGG AGCCATTCAC AGAATTTTTC TCCATTCCAT TTGTGGAGGA GCGGCTAAAG 
CAACACCCAC GGCCGCCAAT CCCACTCTCG CTCCTGCTGA CAGAAGAGGA AGCAGCCCTC 
TACATTCAAT CCTTCTGGAG AGCCTGTGTG GTTCGCTGTG ATCCTGAGAT TCAAGAACTG 
CGTCAGTGGC AGAAGAAACT TCGCGAGGCC AAGCACATTC ACCAGCAAGT CAAAATTTTC 
TGGGCCAAGC AAGAACAAAA AGTGAAATGC AAAATGGAGG ACGATGCAGT ACCTGCAGCC 
AAGATGAAAA TTCCATCATC TTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_016878422.1
CDS	746..1609
Translation	MAAPRQIPSHIVRLKPSCSTDSSFTRTPVPTVSLASRELPVSSWQVTEPSSKNLWEQICKEYEAEQPPFPEGYKVKQEPVITVAPVEEMLFHGFSAEHYFPVSHFTMISRTPCPQDKSETINPKTCSPKEYLETFIFPVLLPGMASLLHQAKKEKCFERKRTKFIACDFLTEWLYNQNPKRAGEPFTEFFSIPFVEERLKQHPRPPIPLSLLLTEEEAALYIQSFWRACVVRCDPEIQELRQWQKKLREAKHIHQQVKIFWAKQEQKVKCKMEDDAVPAAKMKIPSS

Target ORF information:

RefSeq Version	XM_017022933.1
Organism	Homo sapiens(human)
Definition	Homo sapiens IQ motif containing K (IQCK), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017022933.1

ORF Insert Sequence:

ATGGCGGCAC CGCGGCAAAT CCCCAGCCAC ATAGTGCGCC TCAAGCCCAG CTGCTCTACA 
GACTCGTCGT TCACCCGGAC GCCGGTGCCC ACCGTGTCTC TCGCGTCCCG CGAGCTGCCT 
GTCTCGTCGT GGCAGGTCAC CGAGCCGTCA AGCAAGAATC TGTGGGAGCA GATCTGCAAG 
GAGTATGAAG CTGAGCAGCC TCCCTTTCCA GAAGGATATA AAGTCAAACA GGAGCCTGTG 
ATTACGGTTG CGCCAGTAGA GGAAATGCTT TTTCATGGCT TCAGTGCAGA GCACTATTTT 
CCGGTTTCCC ATTTCACCAT GATCTCACGT ACACCCTGTC CTCAAGATAA ATCGGAAACA 
ATCAACCCAA AAACATGTTC TCCCAAAGAA TATTTGGAAA CTTTCATCTT TCCTGTTCTG 
CTTCCCGGAA TGGCTAGCCT GCTTCACCAA GCGAAGAAAG AAAAATGTTT TGAGAGGAAA 
AGAACCAAAT TCATTGCCTG TGATTTTCTG ACTGAGTGGT TATACAACCA AAATCCAAAG 
AGGGCAGGGG AGCCATTCAC AGAATTTTTC TCCATTCCAT TTGTGGAGGA GCGGCTAAAG 
CAACACCCAC GGCCGCCAAT CCCACTCTCG CTCCTGCTGA CAGAAGAGGA AGCAGCCCTC 
TACATTCAAT CCTTCTGGAG AGCCTGTGTG GTTCGCTGTG ATCCTGAGAT TCAAGAACTG 
CGTCAGTGGC AGAAGAAACT TCGCGAGGCC AAGCACATTC ACCAGCAAGT CAAAATTTTC 
TGGGCCAAGC AAGAACAAAA AGTGAAATGC AAAATGGAGG ACGATGCAGT ACCTGCAGCC 
AAGATGAAAA TTCCATCATC TTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

IQCK ( NM_001305121.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001292050.1 Homo sapiens IQ motif containing K (IQCK), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu75283
Clone ID Related Accession (Same CDS sequence)	NM_001305121.1 , XM_011545736.2 , XM_011545736.3
Accession Version	NM_001305121.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 600bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2018-06-30
Organism	Homo sapiens(human)
Product	IQ domain-containing protein K isoform 2
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AF520569.1, AK303998.1, AC134300.3 and AW138537.1. Transcript Variant: This variant (2) lacks an alternate exon in the 5' region and uses a downstream start codon compared to variant 1. It encodes isoform 2 which has a shorter N-terminus compared to isoform 1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. ##Evidence-Data-START## CDS exon combination :: SRR1660803.153154.1, SRR1803611.256675.1 [ECO:0000331] RNAseq introns :: single sample supports all introns SAMEA2145893, SAMEA2159912 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGCTTTTTC ATGGCTTCAG TGCAGAGCAC TATTTTCCGG TTTCCCATTT CACCATGATC 
TCACGTACAC CCTGTCCTCA AGATAAATCG GAAACAATCA ACCCAAAAAC ATGTTCTCCC 
AAAGAATATT TGGAAACTTT CATCTTTCCT GTTCTGCTTC CCGGAATGGC TAGCCTGCTT 
CACCAAGCGA AGAAAGAAAA ATGTTTTGAG AGGAAAAGAA CCAAATTCAT TGCCTGTGAT 
TTTCTGACTG AGTGGTTATA CAACCAAAAT CCAAAGAGGG CAGGGGAGCC ATTCACAGAA 
TTTTTCTCCA TTCCATTTGT GGAGGAGCGG CTAAAGCAAC ACCCACGGCC GCCAATCCCA 
CTCTCGCTCC TGCTGACAGA AGAGGAAGCA GCCCTCTACA TTCAATCCTT CTGGAGAGCC 
TGTGTGGTTC GCTGTGATCC TGAGATTCAA GAACTGCGTC AGTGGCAGAA GAAACTTCGC 
GAGGCCAAGC ACATTCACCA GCAAGTCAAA ATTTTCTGGG CCAAGCAAGA ACAAAAAGTG 
AAATGCAAAA TGGAGGACGA TGCAGTACCT GCAGCCAAGA TGAAAATTCC ATCATCTTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001292050.1
CDS	899..1498
Translation	MLFHGFSAEHYFPVSHFTMISRTPCPQDKSETINPKTCSPKEYLETFIFPVLLPGMASLLHQAKKEKCFERKRTKFIACDFLTEWLYNQNPKRAGEPFTEFFSIPFVEERLKQHPRPPIPLSLLLTEEEAALYIQSFWRACVVRCDPEIQELRQWQKKLREAKHIHQQVKIFWAKQEQKVKCKMEDDAVPAAKMKIPSS

Target ORF information:

RefSeq Version	NM_001305121.1
Organism	Homo sapiens(human)
Definition	Homo sapiens IQ motif containing K (IQCK), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001305121.1

ORF Insert Sequence:

ATGCTTTTTC ATGGCTTCAG TGCAGAGCAC TATTTTCCGG TTTCCCATTT CACCATGATC 
TCACGTACAC CCTGTCCTCA AGATAAATCG GAAACAATCA ACCCAAAAAC ATGTTCTCCC 
AAAGAATATT TGGAAACTTT CATCTTTCCT GTTCTGCTTC CCGGAATGGC TAGCCTGCTT 
CACCAAGCGA AGAAAGAAAA ATGTTTTGAG AGGAAAAGAA CCAAATTCAT TGCCTGTGAT 
TTTCTGACTG AGTGGTTATA CAACCAAAAT CCAAAGAGGG CAGGGGAGCC ATTCACAGAA 
TTTTTCTCCA TTCCATTTGT GGAGGAGCGG CTAAAGCAAC ACCCACGGCC GCCAATCCCA 
CTCTCGCTCC TGCTGACAGA AGAGGAAGCA GCCCTCTACA TTCAATCCTT CTGGAGAGCC 
TGTGTGGTTC GCTGTGATCC TGAGATTCAA GAACTGCGTC AGTGGCAGAA GAAACTTCGC 
GAGGCCAAGC ACATTCACCA GCAAGTCAAA ATTTTCTGGG CCAAGCAAGA ACAAAAAGTG 
AAATGCAAAA TGGAGGACGA TGCAGTACCT GCAGCCAAGA TGAAAATTCC ATCATCTTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

IQCK ( XM_011545736.2 ) cDNA ORF clone, Homo sapiens(human) -> XP_011544038.1 Homo sapiens IQ motif containing K (IQCK), transcript variant X2, mRNA.

Price & Availability↑

CloneID	OHu75283
Clone ID Related Accession (Same CDS sequence)	NM_001305121.1 , XM_011545736.2 , XM_011545736.3
Accession Version	XM_011545736.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 600bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-06-05
Organism	Homo sapiens(human)
Product	IQ domain-containing protein K isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000016.10) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 6, 2016 this sequence version replaced XM_011545736.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGCTTTTTC ATGGCTTCAG TGCAGAGCAC TATTTTCCGG TTTCCCATTT CACCATGATC 
TCACGTACAC CCTGTCCTCA AGATAAATCG GAAACAATCA ACCCAAAAAC ATGTTCTCCC 
AAAGAATATT TGGAAACTTT CATCTTTCCT GTTCTGCTTC CCGGAATGGC TAGCCTGCTT 
CACCAAGCGA AGAAAGAAAA ATGTTTTGAG AGGAAAAGAA CCAAATTCAT TGCCTGTGAT 
TTTCTGACTG AGTGGTTATA CAACCAAAAT CCAAAGAGGG CAGGGGAGCC ATTCACAGAA 
TTTTTCTCCA TTCCATTTGT GGAGGAGCGG CTAAAGCAAC ACCCACGGCC GCCAATCCCA 
CTCTCGCTCC TGCTGACAGA AGAGGAAGCA GCCCTCTACA TTCAATCCTT CTGGAGAGCC 
TGTGTGGTTC GCTGTGATCC TGAGATTCAA GAACTGCGTC AGTGGCAGAA GAAACTTCGC 
GAGGCCAAGC ACATTCACCA GCAAGTCAAA ATTTTCTGGG CCAAGCAAGA ACAAAAAGTG 
AAATGCAAAA TGGAGGACGA TGCAGTACCT GCAGCCAAGA TGAAAATTCC ATCATCTTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_011544038.1
CDS	299..898
Translation	MLFHGFSAEHYFPVSHFTMISRTPCPQDKSETINPKTCSPKEYLETFIFPVLLPGMASLLHQAKKEKCFERKRTKFIACDFLTEWLYNQNPKRAGEPFTEFFSIPFVEERLKQHPRPPIPLSLLLTEEEAALYIQSFWRACVVRCDPEIQELRQWQKKLREAKHIHQQVKIFWAKQEQKVKCKMEDDAVPAAKMKIPSS

Target ORF information:

RefSeq Version	XM_011545736.2
Organism	Homo sapiens(human)
Definition	Homo sapiens IQ motif containing K (IQCK), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011545736.2

ORF Insert Sequence:

ATGCTTTTTC ATGGCTTCAG TGCAGAGCAC TATTTTCCGG TTTCCCATTT CACCATGATC 
TCACGTACAC CCTGTCCTCA AGATAAATCG GAAACAATCA ACCCAAAAAC ATGTTCTCCC 
AAAGAATATT TGGAAACTTT CATCTTTCCT GTTCTGCTTC CCGGAATGGC TAGCCTGCTT 
CACCAAGCGA AGAAAGAAAA ATGTTTTGAG AGGAAAAGAA CCAAATTCAT TGCCTGTGAT 
TTTCTGACTG AGTGGTTATA CAACCAAAAT CCAAAGAGGG CAGGGGAGCC ATTCACAGAA 
TTTTTCTCCA TTCCATTTGT GGAGGAGCGG CTAAAGCAAC ACCCACGGCC GCCAATCCCA 
CTCTCGCTCC TGCTGACAGA AGAGGAAGCA GCCCTCTACA TTCAATCCTT CTGGAGAGCC 
TGTGTGGTTC GCTGTGATCC TGAGATTCAA GAACTGCGTC AGTGGCAGAA GAAACTTCGC 
GAGGCCAAGC ACATTCACCA GCAAGTCAAA ATTTTCTGGG CCAAGCAAGA ACAAAAAGTG 
AAATGCAAAA TGGAGGACGA TGCAGTACCT GCAGCCAAGA TGAAAATTCC ATCATCTTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

IQCK ( XM_011545736.3 ) cDNA ORF clone, Homo sapiens(human) -> XP_011544038.1 Homo sapiens IQ motif containing K (IQCK), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OHu75283
Clone ID Related Accession (Same CDS sequence)	NM_001305121.1 , XM_011545736.2 , XM_011545736.3
Accession Version	XM_011545736.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 600bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	IQ domain-containing protein K isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000016.10) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Mar 26, 2018 this sequence version replaced XM_011545736.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGCTTTTTC ATGGCTTCAG TGCAGAGCAC TATTTTCCGG TTTCCCATTT CACCATGATC 
TCACGTACAC CCTGTCCTCA AGATAAATCG GAAACAATCA ACCCAAAAAC ATGTTCTCCC 
AAAGAATATT TGGAAACTTT CATCTTTCCT GTTCTGCTTC CCGGAATGGC TAGCCTGCTT 
CACCAAGCGA AGAAAGAAAA ATGTTTTGAG AGGAAAAGAA CCAAATTCAT TGCCTGTGAT 
TTTCTGACTG AGTGGTTATA CAACCAAAAT CCAAAGAGGG CAGGGGAGCC ATTCACAGAA 
TTTTTCTCCA TTCCATTTGT GGAGGAGCGG CTAAAGCAAC ACCCACGGCC GCCAATCCCA 
CTCTCGCTCC TGCTGACAGA AGAGGAAGCA GCCCTCTACA TTCAATCCTT CTGGAGAGCC 
TGTGTGGTTC GCTGTGATCC TGAGATTCAA GAACTGCGTC AGTGGCAGAA GAAACTTCGC 
GAGGCCAAGC ACATTCACCA GCAAGTCAAA ATTTTCTGGG CCAAGCAAGA ACAAAAAGTG 
AAATGCAAAA TGGAGGACGA TGCAGTACCT GCAGCCAAGA TGAAAATTCC ATCATCTTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_011544038.1
CDS	299..898
Translation	MLFHGFSAEHYFPVSHFTMISRTPCPQDKSETINPKTCSPKEYLETFIFPVLLPGMASLLHQAKKEKCFERKRTKFIACDFLTEWLYNQNPKRAGEPFTEFFSIPFVEERLKQHPRPPIPLSLLLTEEEAALYIQSFWRACVVRCDPEIQELRQWQKKLREAKHIHQQVKIFWAKQEQKVKCKMEDDAVPAAKMKIPSS

Target ORF information:

RefSeq Version	XM_011545736.3
Organism	Homo sapiens(human)
Definition	Homo sapiens IQ motif containing K (IQCK), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011545736.3

ORF Insert Sequence:

ATGCTTTTTC ATGGCTTCAG TGCAGAGCAC TATTTTCCGG TTTCCCATTT CACCATGATC 
TCACGTACAC CCTGTCCTCA AGATAAATCG GAAACAATCA ACCCAAAAAC ATGTTCTCCC 
AAAGAATATT TGGAAACTTT CATCTTTCCT GTTCTGCTTC CCGGAATGGC TAGCCTGCTT 
CACCAAGCGA AGAAAGAAAA ATGTTTTGAG AGGAAAAGAA CCAAATTCAT TGCCTGTGAT 
TTTCTGACTG AGTGGTTATA CAACCAAAAT CCAAAGAGGG CAGGGGAGCC ATTCACAGAA 
TTTTTCTCCA TTCCATTTGT GGAGGAGCGG CTAAAGCAAC ACCCACGGCC GCCAATCCCA 
CTCTCGCTCC TGCTGACAGA AGAGGAAGCA GCCCTCTACA TTCAATCCTT CTGGAGAGCC 
TGTGTGGTTC GCTGTGATCC TGAGATTCAA GAACTGCGTC AGTGGCAGAA GAAACTTCGC 
GAGGCCAAGC ACATTCACCA GCAAGTCAAA ATTTTCTGGG CCAAGCAAGA ACAAAAAGTG 
AAATGCAAAA TGGAGGACGA TGCAGTACCT GCAGCCAAGA TGAAAATTCC ATCATCTTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

IQCK ( NM_001305122.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001292051.1 Homo sapiens IQ motif containing K (IQCK), transcript variant 3, mRNA.

Price & Availability↑

CloneID	OHu75284
Clone ID Related Accession (Same CDS sequence)	NM_001305122.1
Accession Version	NM_001305122.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 720bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2018-06-30
Organism	Homo sapiens(human)
Product	IQ domain-containing protein K isoform 3
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AF520569.1, AK301933.1, AC134300.3 and AW138537.1. On Mar 22, 2015 this sequence version replaced XM_011545735.1. Transcript Variant: This variant (3) lacks an exon in the coding region, which results in a frameshift and an early stop codon, compared to variant 1. The encoded isoform (3) is shorter and has a distinct C-terminus, compared to isoform 1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. ##Evidence-Data-START## CDS exon combination :: SRR1660805.202591.1, AK301933.1 [ECO:0000331] RNAseq introns :: single sample supports all introns SAMEA2145893, SAMEA2159912 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGCGGCAC CGCGGCAAAT CCCCAGCCAC ATAGTGCGCC TCAAGCCCAG CTGCTCTACA 
GACTCGTCGT TCACCCGGAC GCCGGTGCCC ACCGTGTCTC TCGCGTCCCG CGAGCTGCCT 
GTCTCGTCGT GGCAGGTCAC CGAGCCGTCA AGCAAGAATC TGTGGGAGCA GATCTGCAAG 
GAGTATGAAG CTGAGCAGCC TCCCTTTCCA GAAGGATATA AAGTCAAACA GGAGCCTGTG 
ATTACGGTTG CGCCAGTAGA GGAAATGCTT TTTCATGGCT TCAGTGCAGA GCACTATTTT 
CCGGTTTCCC ATTTCACCAT GATCTCACGT ACACCCTGTC CTCAAGATAA ATCGGAAACA 
ATCAACCCAA AAACATGTTC TCCCAAAGAA TATTTGGAAA CTTTCATCTT TCCTGTTCTG 
CTTCCCGGAA TGGCTAGCCT GCTTCACCAA GCGAAGAAAG AAAAATGTTT TGAGAGGAAA 
AGAACCAAAT TCATTGCCTG TGATTTTCTG ACTGAGTGGT TATACAACCA AAATCCAAAG 
AGGGCAGGGG AGCCATTCAC AGAATTTTTC TCCATTCCAT TTGTGGAGGA GCGGCTAAAG 
CAACAGTTCG CTGTGATCCT GAGATTCAAG AACTGCGTCA GTGGCAGAAG AAACTTCGCG 
AGGCCAAGCA CATTCACCAG CAAGTCAAAA TTTTCTGGGC CAAGCAAGAA CAAAAAGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001292051.1
CDS	700..1419
Translation	MAAPRQIPSHIVRLKPSCSTDSSFTRTPVPTVSLASRELPVSSWQVTEPSSKNLWEQICKEYEAEQPPFPEGYKVKQEPVITVAPVEEMLFHGFSAEHYFPVSHFTMISRTPCPQDKSETINPKTCSPKEYLETFIFPVLLPGMASLLHQAKKEKCFERKRTKFIACDFLTEWLYNQNPKRAGEPFTEFFSIPFVEERLKQQFAVILRFKNCVSGRRNFARPSTFTSKSKFSGPSKNKK

Target ORF information:

RefSeq Version	NM_001305122.1
Organism	Homo sapiens(human)
Definition	Homo sapiens IQ motif containing K (IQCK), transcript variant 3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001305122.1

ORF Insert Sequence:

ATGGCGGCAC CGCGGCAAAT CCCCAGCCAC ATAGTGCGCC TCAAGCCCAG CTGCTCTACA 
GACTCGTCGT TCACCCGGAC GCCGGTGCCC ACCGTGTCTC TCGCGTCCCG CGAGCTGCCT 
GTCTCGTCGT GGCAGGTCAC CGAGCCGTCA AGCAAGAATC TGTGGGAGCA GATCTGCAAG 
GAGTATGAAG CTGAGCAGCC TCCCTTTCCA GAAGGATATA AAGTCAAACA GGAGCCTGTG 
ATTACGGTTG CGCCAGTAGA GGAAATGCTT TTTCATGGCT TCAGTGCAGA GCACTATTTT 
CCGGTTTCCC ATTTCACCAT GATCTCACGT ACACCCTGTC CTCAAGATAA ATCGGAAACA 
ATCAACCCAA AAACATGTTC TCCCAAAGAA TATTTGGAAA CTTTCATCTT TCCTGTTCTG 
CTTCCCGGAA TGGCTAGCCT GCTTCACCAA GCGAAGAAAG AAAAATGTTT TGAGAGGAAA 
AGAACCAAAT TCATTGCCTG TGATTTTCTG ACTGAGTGGT TATACAACCA AAATCCAAAG 
AGGGCAGGGG AGCCATTCAC AGAATTTTTC TCCATTCCAT TTGTGGAGGA GCGGCTAAAG 
CAACAGTTCG CTGTGATCCT GAGATTCAAG AACTGCGTCA GTGGCAGAAG AAACTTCGCG 
AGGCCAAGCA CATTCACCAG CAAGTCAAAA TTTTCTGGGC CAAGCAAGAA CAAAAAGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Genome-wide association study in obsessive-compulsive disorder: results from the OCGAS.
Molecular psychiatry20(3)337-44(2015 Mar)
Mattheisen M,Samuels JF,Wang Y,Greenberg BD,Fyer AJ,McCracken JT,Geller DA,Murphy DL,Knowles JA,Grados MA,Riddle MA,Rasmussen SA,McLaughlin NC,Nurmi EL,Askland KD,Qin HD,Cullen BA,Piacentini J,Pauls DL,Bienvenu OJ,Stewart SE,Liang KY,Goes FS,Maher B,Pulver AE,Shugart YY,Valle D,Lange C,Nestadt G

Genetic variation at the CELF1 (CUGBP, elav-like family member 1 gene) locus is genome-wide associated with Alzheimer's disease and obesity.
American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics165B(4)283-93(2014 Jun)
Hinney A,Albayrak O,Antel J,Volckmar AL,Sims R,Chapman J,Harold D,Gerrish A,Heid IM,Winkler TW,Scherag A,Wiltfang J,Williams J,Hebebrand J,,,

Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study.
Diabetes care33(10)2250-3(2010 Oct)
Bailey SD,Xie C,Do R,Montpetit A,Diaz R,Mohan V,Keavney B,Yusuf S,Gerstein HC,Engert JC,Anand S,

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IQCK cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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