CCR7 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	CCR7
Entrez Gene ID	1236
Full Name	C-C motif chemokine receptor 7
Synonyms	BLR2,CC-CKR-7,CCR-7,CD197,CDw197,CMKBR7,EBI1
General protein information	Preferred Names C-C motif chemokine receptor 7 Names C-C chemokine receptor type 7 Bukitt's lymphoma receptor 2 CC chemokine receptor 7 EBV-induced G protein-coupled receptor 1 Epstein-Barr virus induced gene 1 Epstein-Barr virus-induced G-protein coupled receptor 1 MIP-3 beta receptor chemokine (C-C motif) receptor 7 lymphocyte-specific G protein-coupled peptide receptor
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 17 Map Location: 17q21.2
Summary	The protein encoded by this gene is a member of the G protein-coupled receptor family. This receptor was identified as a gene induced by the Epstein-Barr virus (EBV), and is thought to be a mediator of EBV effects on B lymphocytes. This receptor is expressed in various lymphoid tissues and activates B and T lymphocytes. It has been shown to control the migration of memory T cells to inflamed tissues, as well as stimulate dendritic cell maturation. The chemokine (C-C motif) ligand 19 (CCL19/ECL) has been reported to be a specific ligand of this receptor. Signals mediated by this receptor regulate T cell homeostasis in lymph nodes, and may also function in the activation and polarization of T cells, and in chronic inflammation pathogenesis. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Sep 2014].
Disorder MIM:	600242

mRNA and Protein(s)

mRNA	Protein	Name
NM_001838.4	NP_001829.1	C-C chemokine receptor type 7 isoform a precursor
NM_001301714.1	NP_001288643.1	C-C chemokine receptor type 7 isoform b
NM_001301716.1	NP_001288645.1	C-C chemokine receptor type 7 isoform c precursor
NM_001301717.1	NP_001288646.1	C-C chemokine receptor type 7 isoform c precursor
NM_001301718.1	NP_001288647.1	C-C chemokine receptor type 7 isoform c precursor
NM_001838.3	NP_001829.1	C-C chemokine receptor type 7 isoform a precursor
NM_001301714.2	NP_001288643.1	C-C chemokine receptor type 7 isoform b

Pathways from BioSystems

Homologies

Bos taurus (cattle)	CCR7	NP_001020101.2
Danio rerio (zebrafish)	ccr7	NP_001092213.1
Pan troglodytes (chimpanzee)	CCR7	XP_511477.3
	CCR7	NP_001028056.1
Canis lupus familiaris (dog)	CCR7	XP_548131.2
Xenopus tropicalis (tropical clawed frog)	ccr7	XP_004918750.1
Homo sapiens (human)	CCR7	NP_001829.1
Mus musculus (house mouse)	Ccr7	NP_031745.2
Rattus norvegicus (Norway rat)	Ccr7	NP_955783.1
Gallus gallus (chicken)	CCR7	NP_001185681.1

Gene Ontology
Bibliography

Related articles in PubMed

MiR-1275 promotes cell migration, invasion and proliferation in squamous cell carcinoma of head and neck via up-regulating IGF-1R and CCR7.
Liu MD, Wu H, Wang S, Pang P, Jin S, Sun CF, Liu FY
Gene(2017 Dec)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

that CCR7 mediates TGF-beta1-induced MMP2/9 expression through NF-kappaB signaling
Title: CCR7 Mediates TGF-?1-Induced Human Malignant Glioma Invasion, Migration, and Epithelial-Mesenchymal Transition by Activating MMP2/9 Through the Nuclear Factor KappaB Signaling Pathway.

Report an increased percentage of peripheral CCR7 T cells accompanied by endothelial dysfunction in patients with ankylosing spondylitis.
Title: Endothelial dysfunction is independent of inflammation and altered CCR7 T cell expression in patients with ankylosing spondylitis.

Results show that upregulation of CCR7 promotes cell proliferation and inflammation in A549 non-small cell lung cancer cells. However, silencing of CCR7 via siRNA treatment promotes cell apoptosis and suppresses the inflammatory response and TGF-beta1-induced EMT, which may be associated with NF-kappaB signaling.
Title: Inhibition of CCR7 promotes NF-?B-dependent apoptosis and suppresses epithelial-mesenchymal transition in non-small cell lung cancer.

The analysis of gene amplification and mRNA levels showed the expression of CCR7 in breast cancer correlated with better prognosis.
Title: High Expression of CCR7 Predicts Lymph Node Metastasis and Good Prognosis in Triple Negative Breast Cancer.

High tumoral CCR7 expression correlated with potential lymphatic involvement and poor prognosis of metastatic renal cell carcinoma patients treated with tyrosine kinase inhibitors.
Title: Prognostic value of CC-chemokine receptor seven expression in patients with metastatic renal cell carcinoma treated with tyrosine kinase inhibitor.

The following CCR7 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the CCR7 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu24012	NM_001838.4 Latest version!	Homo sapiens C-C motif chemokine receptor 7 (CCR7), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$159.50-$223.30 $319.00
OHu56953	NM_001301714.2 Latest version!	Homo sapiens C-C motif chemokine receptor 7 (CCR7), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$139.30 $199.00
OHu56954	NM_001301718.1 Latest version!	Homo sapiens C-C motif chemokine receptor 7 (CCR7), transcript variant 5, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$223.30 $319.00
OHu56954	NM_001301717.1 Latest version!	Homo sapiens C-C motif chemokine receptor 7 (CCR7), transcript variant 4, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$223.30 $319.00
OHu56954	NM_001301716.1 Latest version!	Homo sapiens C-C motif chemokine receptor 7 (CCR7), transcript variant 3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$223.30 $319.00
View Old Accession Versions >>
OHu24012	NM_001838.3	Homo sapiens C-C motif chemokine receptor 7 (CCR7), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$159.50-$223.30 $319.00
OHu56953	NM_001301714.1	Homo sapiens C-C motif chemokine receptor 7 (CCR7), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$139.30 $199.00
Hide Old Accession Versions >>

ORF Online Only Promotion

Next-day Shipping ORF Clones ( in default vector with tag)
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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

CCR7 ( NM_001838.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_001829.1 Homo sapiens C-C motif chemokine receptor 7 (CCR7), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu24012
Clone ID Related Accession (Same CDS sequence)	NM_001838.4 , NM_001838.3
Accession Version	NM_001838.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1137bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-30
Organism	Homo sapiens(human)
Product	C-C chemokine receptor type 7 isoform a precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from L31581.1 and BC035343.1. On Nov 22, 2018 this sequence version replaced NM_001838.3. Transcript Variant: This variant (1) encodes the longest isoform (a). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK127810.1, L08176.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000246657.2/ ENSP00000246657.2 RefSeq Select criteria :: based on conservation, expression, longest protein ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGGACCTGG GGAAACCAAT GAAAAGCGTG CTGGTGGTGG CTCTCCTTGT CATTTTCCAG 
GTATGCCTGT GTCAAGATGA GGTCACGGAC GATTACATCG GAGACAACAC CACAGTGGAC 
TACACTTTGT TCGAGTCTTT GTGCTCCAAG AAGGACGTGC GGAACTTTAA AGCCTGGTTC 
CTCCCTATCA TGTACTCCAT CATTTGTTTC GTGGGCCTAC TGGGCAATGG GCTGGTCGTG 
TTGACCTATA TCTATTTCAA GAGGCTCAAG ACCATGACCG ATACCTACCT GCTCAACCTG 
GCGGTGGCAG ACATCCTCTT CCTCCTGACC CTTCCCTTCT GGGCCTACAG CGCGGCCAAG 
TCCTGGGTCT TCGGTGTCCA CTTTTGCAAG CTCATCTTTG CCATCTACAA GATGAGCTTC 
TTCAGTGGCA TGCTCCTACT TCTTTGCATC AGCATTGACC GCTACGTGGC CATCGTCCAG 
GCTGTCTCAG CTCACCGCCA CCGTGCCCGC GTCCTTCTCA TCAGCAAGCT GTCCTGTGTG 
GGCATCTGGA TACTAGCCAC AGTGCTCTCC ATCCCAGAGC TCCTGTACAG TGACCTCCAG 
AGGAGCAGCA GTGAGCAAGC GATGCGATGC TCTCTCATCA CAGAGCATGT GGAGGCCTTT 
ATCACCATCC AGGTGGCCCA GATGGTGATC GGCTTTCTGG TCCCCCTGCT GGCCATGAGC 
TTCTGTTACC TTGTCATCAT CCGCACCCTG CTCCAGGCAC GCAACTTTGA GCGCAACAAG 
GCCATCAAGG TGATCATCGC TGTGGTCGTG GTCTTCATAG TCTTCCAGCT GCCCTACAAT 
GGGGTGGTCC TGGCCCAGAC GGTGGCCAAC TTCAACATCA CCAGTAGCAC CTGTGAGCTC 
AGTAAGCAAC TCAACATCGC CTACGACGTC ACCTACAGCC TGGCCTGCGT CCGCTGCTGC 
GTCAACCCTT TCTTGTACGC CTTCATCGGC GTCAAGTTCC GCAACGATCT CTTCAAGCTC 
TTCAAGGACC TGGGCTGCCT CAGCCAGGAG CAGCTCCGGC AGTGGTCTTC CTGTCGGCAC 
ATCCGGCGCT CCTCCATGAG TGTGGAGGCC GAGACCACCA CCACCTTCTC CCCATAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001829.1
CDS	64..1200
Translation	MDLGKPMKSVLVVALLVIFQVCLCQDEVTDDYIGDNTTVDYTLFESLCSKKDVRNFKAWFLPIMYSIICFVGLLGNGLVVLTYIYFKRLKTMTDTYLLNLAVADILFLLTLPFWAYSAAKSWVFGVHFCKLIFAIYKMSFFSGMLLLLCISIDRYVAIVQAVSAHRHRARVLLISKLSCVGIWILATVLSIPELLYSDLQRSSSEQAMRCSLITEHVEAFITIQVAQMVIGFLVPLLAMSFCYLVIIRTLLQARNFERNKAIKVIIAVVVVFIVFQLPYNGVVLAQTVANFNITSSTCELSKQLNIAYDVTYSLACVRCCVNPFLYAFIGVKFRNDLFKLFKDLGCLSQEQLRQWSSCRHIRRSSMSVEAETTTTFSP

Target ORF information:

RefSeq Version	NM_001838.4
Organism	Homo sapiens(human)
Definition	Homo sapiens C-C motif chemokine receptor 7 (CCR7), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001838.4

ORF Insert Sequence:

ATGGACCTGG GGAAACCAAT GAAAAGCGTG CTGGTGGTGG CTCTCCTTGT CATTTTCCAG 
GTATGCCTGT GTCAAGATGA GGTCACGGAC GATTACATCG GAGACAACAC CACAGTGGAC 
TACACTTTGT TCGAGTCTTT GTGCTCCAAG AAGGACGTGC GGAACTTTAA AGCCTGGTTC 
CTCCCTATCA TGTACTCCAT CATTTGTTTC GTGGGCCTAC TGGGCAATGG GCTGGTCGTG 
TTGACCTATA TCTATTTCAA GAGGCTCAAG ACCATGACCG ATACCTACCT GCTCAACCTG 
GCGGTGGCAG ACATCCTCTT CCTCCTGACC CTTCCCTTCT GGGCCTACAG CGCGGCCAAG 
TCCTGGGTCT TCGGTGTCCA CTTTTGCAAG CTCATCTTTG CCATCTACAA GATGAGCTTC 
TTCAGTGGCA TGCTCCTACT TCTTTGCATC AGCATTGACC GCTACGTGGC CATCGTCCAG 
GCTGTCTCAG CTCACCGCCA CCGTGCCCGC GTCCTTCTCA TCAGCAAGCT GTCCTGTGTG 
GGCATCTGGA TACTAGCCAC AGTGCTCTCC ATCCCAGAGC TCCTGTACAG TGACCTCCAG 
AGGAGCAGCA GTGAGCAAGC GATGCGATGC TCTCTCATCA CAGAGCATGT GGAGGCCTTT 
ATCACCATCC AGGTGGCCCA GATGGTGATC GGCTTTCTGG TCCCCCTGCT GGCCATGAGC 
TTCTGTTACC TTGTCATCAT CCGCACCCTG CTCCAGGCAC GCAACTTTGA GCGCAACAAG 
GCCATCAAGG TGATCATCGC TGTGGTCGTG GTCTTCATAG TCTTCCAGCT GCCCTACAAT 
GGGGTGGTCC TGGCCCAGAC GGTGGCCAAC TTCAACATCA CCAGTAGCAC CTGTGAGCTC 
AGTAAGCAAC TCAACATCGC CTACGACGTC ACCTACAGCC TGGCCTGCGT CCGCTGCTGC 
GTCAACCCTT TCTTGTACGC CTTCATCGGC GTCAAGTTCC GCAACGATCT CTTCAAGCTC 
TTCAAGGACC TGGGCTGCCT CAGCCAGGAG CAGCTCCGGC AGTGGTCTTC CTGTCGGCAC 
ATCCGGCGCT CCTCCATGAG TGTGGAGGCC GAGACCACCA CCACCTTCTC CCCATAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

CCR7 ( NM_001838.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_001829.1 Homo sapiens C-C motif chemokine receptor 7 (CCR7), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu24012
Clone ID Related Accession (Same CDS sequence)	NM_001838.4 , NM_001838.3
Accession Version	NM_001838.3	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1137bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-12-05
Organism	Homo sapiens(human)
Product	C-C chemokine receptor type 7 isoform a precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DA814913.1, L31581.1 and BC035343.1. On Jun 24, 2010 this sequence version replaced NM_001838.2. Transcript Variant: This variant (1) encodes the longest isoform (a). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC035343.1, AK127810.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGACCTGG GGAAACCAAT GAAAAGCGTG CTGGTGGTGG CTCTCCTTGT CATTTTCCAG 
GTATGCCTGT GTCAAGATGA GGTCACGGAC GATTACATCG GAGACAACAC CACAGTGGAC 
TACACTTTGT TCGAGTCTTT GTGCTCCAAG AAGGACGTGC GGAACTTTAA AGCCTGGTTC 
CTCCCTATCA TGTACTCCAT CATTTGTTTC GTGGGCCTAC TGGGCAATGG GCTGGTCGTG 
TTGACCTATA TCTATTTCAA GAGGCTCAAG ACCATGACCG ATACCTACCT GCTCAACCTG 
GCGGTGGCAG ACATCCTCTT CCTCCTGACC CTTCCCTTCT GGGCCTACAG CGCGGCCAAG 
TCCTGGGTCT TCGGTGTCCA CTTTTGCAAG CTCATCTTTG CCATCTACAA GATGAGCTTC 
TTCAGTGGCA TGCTCCTACT TCTTTGCATC AGCATTGACC GCTACGTGGC CATCGTCCAG 
GCTGTCTCAG CTCACCGCCA CCGTGCCCGC GTCCTTCTCA TCAGCAAGCT GTCCTGTGTG 
GGCATCTGGA TACTAGCCAC AGTGCTCTCC ATCCCAGAGC TCCTGTACAG TGACCTCCAG 
AGGAGCAGCA GTGAGCAAGC GATGCGATGC TCTCTCATCA CAGAGCATGT GGAGGCCTTT 
ATCACCATCC AGGTGGCCCA GATGGTGATC GGCTTTCTGG TCCCCCTGCT GGCCATGAGC 
TTCTGTTACC TTGTCATCAT CCGCACCCTG CTCCAGGCAC GCAACTTTGA GCGCAACAAG 
GCCATCAAGG TGATCATCGC TGTGGTCGTG GTCTTCATAG TCTTCCAGCT GCCCTACAAT 
GGGGTGGTCC TGGCCCAGAC GGTGGCCAAC TTCAACATCA CCAGTAGCAC CTGTGAGCTC 
AGTAAGCAAC TCAACATCGC CTACGACGTC ACCTACAGCC TGGCCTGCGT CCGCTGCTGC 
GTCAACCCTT TCTTGTACGC CTTCATCGGC GTCAAGTTCC GCAACGATCT CTTCAAGCTC 
TTCAAGGACC TGGGCTGCCT CAGCCAGGAG CAGCTCCGGC AGTGGTCTTC CTGTCGGCAC 
ATCCGGCGCT CCTCCATGAG TGTGGAGGCC GAGACCACCA CCACCTTCTC CCCATAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001829.1
CDS	76..1212
Translation	MDLGKPMKSVLVVALLVIFQVCLCQDEVTDDYIGDNTTVDYTLFESLCSKKDVRNFKAWFLPIMYSIICFVGLLGNGLVVLTYIYFKRLKTMTDTYLLNLAVADILFLLTLPFWAYSAAKSWVFGVHFCKLIFAIYKMSFFSGMLLLLCISIDRYVAIVQAVSAHRHRARVLLISKLSCVGIWILATVLSIPELLYSDLQRSSSEQAMRCSLITEHVEAFITIQVAQMVIGFLVPLLAMSFCYLVIIRTLLQARNFERNKAIKVIIAVVVVFIVFQLPYNGVVLAQTVANFNITSSTCELSKQLNIAYDVTYSLACVRCCVNPFLYAFIGVKFRNDLFKLFKDLGCLSQEQLRQWSSCRHIRRSSMSVEAETTTTFSP

Target ORF information:

RefSeq Version	NM_001838.3
Organism	Homo sapiens(human)
Definition	Homo sapiens C-C motif chemokine receptor 7 (CCR7), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001838.3

ORF Insert Sequence:

ATGGACCTGG GGAAACCAAT GAAAAGCGTG CTGGTGGTGG CTCTCCTTGT CATTTTCCAG 
GTATGCCTGT GTCAAGATGA GGTCACGGAC GATTACATCG GAGACAACAC CACAGTGGAC 
TACACTTTGT TCGAGTCTTT GTGCTCCAAG AAGGACGTGC GGAACTTTAA AGCCTGGTTC 
CTCCCTATCA TGTACTCCAT CATTTGTTTC GTGGGCCTAC TGGGCAATGG GCTGGTCGTG 
TTGACCTATA TCTATTTCAA GAGGCTCAAG ACCATGACCG ATACCTACCT GCTCAACCTG 
GCGGTGGCAG ACATCCTCTT CCTCCTGACC CTTCCCTTCT GGGCCTACAG CGCGGCCAAG 
TCCTGGGTCT TCGGTGTCCA CTTTTGCAAG CTCATCTTTG CCATCTACAA GATGAGCTTC 
TTCAGTGGCA TGCTCCTACT TCTTTGCATC AGCATTGACC GCTACGTGGC CATCGTCCAG 
GCTGTCTCAG CTCACCGCCA CCGTGCCCGC GTCCTTCTCA TCAGCAAGCT GTCCTGTGTG 
GGCATCTGGA TACTAGCCAC AGTGCTCTCC ATCCCAGAGC TCCTGTACAG TGACCTCCAG 
AGGAGCAGCA GTGAGCAAGC GATGCGATGC TCTCTCATCA CAGAGCATGT GGAGGCCTTT 
ATCACCATCC AGGTGGCCCA GATGGTGATC GGCTTTCTGG TCCCCCTGCT GGCCATGAGC 
TTCTGTTACC TTGTCATCAT CCGCACCCTG CTCCAGGCAC GCAACTTTGA GCGCAACAAG 
GCCATCAAGG TGATCATCGC TGTGGTCGTG GTCTTCATAG TCTTCCAGCT GCCCTACAAT 
GGGGTGGTCC TGGCCCAGAC GGTGGCCAAC TTCAACATCA CCAGTAGCAC CTGTGAGCTC 
AGTAAGCAAC TCAACATCGC CTACGACGTC ACCTACAGCC TGGCCTGCGT CCGCTGCTGC 
GTCAACCCTT TCTTGTACGC CTTCATCGGC GTCAAGTTCC GCAACGATCT CTTCAAGCTC 
TTCAAGGACC TGGGCTGCCT CAGCCAGGAG CAGCTCCGGC AGTGGTCTTC CTGTCGGCAC 
ATCCGGCGCT CCTCCATGAG TGTGGAGGCC GAGACCACCA CCACCTTCTC CCCATAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

CCR7 ( NM_001301714.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001288643.1 Homo sapiens C-C motif chemokine receptor 7 (CCR7), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu56953
Clone ID Related Accession (Same CDS sequence)	NM_001301714.1 , NM_001301714.2
Accession Version	NM_001301714.1	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 948bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2018-12-22
Organism	Homo sapiens(human)
Product	C-C chemokine receptor type 7 isoform b
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DA814913.1, BI910219.1 and BC035343.1. Transcript Variant: This variant (2) lacks an alternate exon, and it thus differs in its 5' UTR and initiates translation at a downstream in-frame start codon, compared to variant 1. The encoded isoform (b) is shorter at the N-terminus, compared to isoform a. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BI910219.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1968540 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGTACTCCA TCATTTGTTT CGTGGGCCTA CTGGGCAATG GGCTGGTCGT GTTGACCTAT 
ATCTATTTCA AGAGGCTCAA GACCATGACC GATACCTACC TGCTCAACCT GGCGGTGGCA 
GACATCCTCT TCCTCCTGAC CCTTCCCTTC TGGGCCTACA GCGCGGCCAA GTCCTGGGTC 
TTCGGTGTCC ACTTTTGCAA GCTCATCTTT GCCATCTACA AGATGAGCTT CTTCAGTGGC 
ATGCTCCTAC TTCTTTGCAT CAGCATTGAC CGCTACGTGG CCATCGTCCA GGCTGTCTCA 
GCTCACCGCC ACCGTGCCCG CGTCCTTCTC ATCAGCAAGC TGTCCTGTGT GGGCATCTGG 
ATACTAGCCA CAGTGCTCTC CATCCCAGAG CTCCTGTACA GTGACCTCCA GAGGAGCAGC 
AGTGAGCAAG CGATGCGATG CTCTCTCATC ACAGAGCATG TGGAGGCCTT TATCACCATC 
CAGGTGGCCC AGATGGTGAT CGGCTTTCTG GTCCCCCTGC TGGCCATGAG CTTCTGTTAC 
CTTGTCATCA TCCGCACCCT GCTCCAGGCA CGCAACTTTG AGCGCAACAA GGCCATCAAG 
GTGATCATCG CTGTGGTCGT GGTCTTCATA GTCTTCCAGC TGCCCTACAA TGGGGTGGTC 
CTGGCCCAGA CGGTGGCCAA CTTCAACATC ACCAGTAGCA CCTGTGAGCT CAGTAAGCAA 
CTCAACATCG CCTACGACGT CACCTACAGC CTGGCCTGCG TCCGCTGCTG CGTCAACCCT 
TTCTTGTACG CCTTCATCGG CGTCAAGTTC CGCAACGATC TCTTCAAGCT CTTCAAGGAC 
CTGGGCTGCC TCAGCCAGGA GCAGCTCCGG CAGTGGTCTT CCTGTCGGCA CATCCGGCGC 
TCCTCCATGA GTGTGGAGGC CGAGACCACC ACCACCTTCT CCCCATAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001288643.1
CDS	215..1162
Translation	MYSIICFVGLLGNGLVVLTYIYFKRLKTMTDTYLLNLAVADILFLLTLPFWAYSAAKSWVFGVHFCKLIFAIYKMSFFSGMLLLLCISIDRYVAIVQAVSAHRHRARVLLISKLSCVGIWILATVLSIPELLYSDLQRSSSEQAMRCSLITEHVEAFITIQVAQMVIGFLVPLLAMSFCYLVIIRTLLQARNFERNKAIKVIIAVVVVFIVFQLPYNGVVLAQTVANFNITSSTCELSKQLNIAYDVTYSLACVRCCVNPFLYAFIGVKFRNDLFKLFKDLGCLSQEQLRQWSSCRHIRRSSMSVEAETTTTFSP

Target ORF information:

RefSeq Version	NM_001301714.1
Organism	Homo sapiens(human)
Definition	Homo sapiens C-C motif chemokine receptor 7 (CCR7), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001301714.1

ORF Insert Sequence:

ATGTACTCCA TCATTTGTTT CGTGGGCCTA CTGGGCAATG GGCTGGTCGT GTTGACCTAT 
ATCTATTTCA AGAGGCTCAA GACCATGACC GATACCTACC TGCTCAACCT GGCGGTGGCA 
GACATCCTCT TCCTCCTGAC CCTTCCCTTC TGGGCCTACA GCGCGGCCAA GTCCTGGGTC 
TTCGGTGTCC ACTTTTGCAA GCTCATCTTT GCCATCTACA AGATGAGCTT CTTCAGTGGC 
ATGCTCCTAC TTCTTTGCAT CAGCATTGAC CGCTACGTGG CCATCGTCCA GGCTGTCTCA 
GCTCACCGCC ACCGTGCCCG CGTCCTTCTC ATCAGCAAGC TGTCCTGTGT GGGCATCTGG 
ATACTAGCCA CAGTGCTCTC CATCCCAGAG CTCCTGTACA GTGACCTCCA GAGGAGCAGC 
AGTGAGCAAG CGATGCGATG CTCTCTCATC ACAGAGCATG TGGAGGCCTT TATCACCATC 
CAGGTGGCCC AGATGGTGAT CGGCTTTCTG GTCCCCCTGC TGGCCATGAG CTTCTGTTAC 
CTTGTCATCA TCCGCACCCT GCTCCAGGCA CGCAACTTTG AGCGCAACAA GGCCATCAAG 
GTGATCATCG CTGTGGTCGT GGTCTTCATA GTCTTCCAGC TGCCCTACAA TGGGGTGGTC 
CTGGCCCAGA CGGTGGCCAA CTTCAACATC ACCAGTAGCA CCTGTGAGCT CAGTAAGCAA 
CTCAACATCG CCTACGACGT CACCTACAGC CTGGCCTGCG TCCGCTGCTG CGTCAACCCT 
TTCTTGTACG CCTTCATCGG CGTCAAGTTC CGCAACGATC TCTTCAAGCT CTTCAAGGAC 
CTGGGCTGCC TCAGCCAGGA GCAGCTCCGG CAGTGGTCTT CCTGTCGGCA CATCCGGCGC 
TCCTCCATGA GTGTGGAGGC CGAGACCACC ACCACCTTCT CCCCATAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

CCR7 ( NM_001301714.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_001288643.1 Homo sapiens C-C motif chemokine receptor 7 (CCR7), transcript variant 2, mRNA.

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CloneID	OHu56953
Clone ID Related Accession (Same CDS sequence)	NM_001301714.1 , NM_001301714.2
Accession Version	NM_001301714.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 948bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-11-02
Organism	Homo sapiens(human)
Product	C-C chemokine receptor type 7 isoform b
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DA814913.1, BI910219.1 and BC035343.1. On May 31, 2019 this sequence version replaced NM_001301714.1. Transcript Variant: This variant (2) lacks an alternate exon, and it thus differs in its 5' UTR and initiates translation at a downstream in-frame start codon, compared to variant 1. The encoded isoform (b) is shorter at the N-terminus, compared to isoform a. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BI910219.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1968540 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGTACTCCA TCATTTGTTT CGTGGGCCTA CTGGGCAATG GGCTGGTCGT GTTGACCTAT 
ATCTATTTCA AGAGGCTCAA GACCATGACC GATACCTACC TGCTCAACCT GGCGGTGGCA 
GACATCCTCT TCCTCCTGAC CCTTCCCTTC TGGGCCTACA GCGCGGCCAA GTCCTGGGTC 
TTCGGTGTCC ACTTTTGCAA GCTCATCTTT GCCATCTACA AGATGAGCTT CTTCAGTGGC 
ATGCTCCTAC TTCTTTGCAT CAGCATTGAC CGCTACGTGG CCATCGTCCA GGCTGTCTCA 
GCTCACCGCC ACCGTGCCCG CGTCCTTCTC ATCAGCAAGC TGTCCTGTGT GGGCATCTGG 
ATACTAGCCA CAGTGCTCTC CATCCCAGAG CTCCTGTACA GTGACCTCCA GAGGAGCAGC 
AGTGAGCAAG CGATGCGATG CTCTCTCATC ACAGAGCATG TGGAGGCCTT TATCACCATC 
CAGGTGGCCC AGATGGTGAT CGGCTTTCTG GTCCCCCTGC TGGCCATGAG CTTCTGTTAC 
CTTGTCATCA TCCGCACCCT GCTCCAGGCA CGCAACTTTG AGCGCAACAA GGCCATCAAG 
GTGATCATCG CTGTGGTCGT GGTCTTCATA GTCTTCCAGC TGCCCTACAA TGGGGTGGTC 
CTGGCCCAGA CGGTGGCCAA CTTCAACATC ACCAGTAGCA CCTGTGAGCT CAGTAAGCAA 
CTCAACATCG CCTACGACGT CACCTACAGC CTGGCCTGCG TCCGCTGCTG CGTCAACCCT 
TTCTTGTACG CCTTCATCGG CGTCAAGTTC CGCAACGATC TCTTCAAGCT CTTCAAGGAC 
CTGGGCTGCC TCAGCCAGGA GCAGCTCCGG CAGTGGTCTT CCTGTCGGCA CATCCGGCGC 
TCCTCCATGA GTGTGGAGGC CGAGACCACC ACCACCTTCT CCCCATAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001288643.1
CDS	203..1150
Translation	MYSIICFVGLLGNGLVVLTYIYFKRLKTMTDTYLLNLAVADILFLLTLPFWAYSAAKSWVFGVHFCKLIFAIYKMSFFSGMLLLLCISIDRYVAIVQAVSAHRHRARVLLISKLSCVGIWILATVLSIPELLYSDLQRSSSEQAMRCSLITEHVEAFITIQVAQMVIGFLVPLLAMSFCYLVIIRTLLQARNFERNKAIKVIIAVVVVFIVFQLPYNGVVLAQTVANFNITSSTCELSKQLNIAYDVTYSLACVRCCVNPFLYAFIGVKFRNDLFKLFKDLGCLSQEQLRQWSSCRHIRRSSMSVEAETTTTFSP

Target ORF information:

RefSeq Version	NM_001301714.2
Organism	Homo sapiens(human)
Definition	Homo sapiens C-C motif chemokine receptor 7 (CCR7), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001301714.2

ORF Insert Sequence:

ATGTACTCCA TCATTTGTTT CGTGGGCCTA CTGGGCAATG GGCTGGTCGT GTTGACCTAT 
ATCTATTTCA AGAGGCTCAA GACCATGACC GATACCTACC TGCTCAACCT GGCGGTGGCA 
GACATCCTCT TCCTCCTGAC CCTTCCCTTC TGGGCCTACA GCGCGGCCAA GTCCTGGGTC 
TTCGGTGTCC ACTTTTGCAA GCTCATCTTT GCCATCTACA AGATGAGCTT CTTCAGTGGC 
ATGCTCCTAC TTCTTTGCAT CAGCATTGAC CGCTACGTGG CCATCGTCCA GGCTGTCTCA 
GCTCACCGCC ACCGTGCCCG CGTCCTTCTC ATCAGCAAGC TGTCCTGTGT GGGCATCTGG 
ATACTAGCCA CAGTGCTCTC CATCCCAGAG CTCCTGTACA GTGACCTCCA GAGGAGCAGC 
AGTGAGCAAG CGATGCGATG CTCTCTCATC ACAGAGCATG TGGAGGCCTT TATCACCATC 
CAGGTGGCCC AGATGGTGAT CGGCTTTCTG GTCCCCCTGC TGGCCATGAG CTTCTGTTAC 
CTTGTCATCA TCCGCACCCT GCTCCAGGCA CGCAACTTTG AGCGCAACAA GGCCATCAAG 
GTGATCATCG CTGTGGTCGT GGTCTTCATA GTCTTCCAGC TGCCCTACAA TGGGGTGGTC 
CTGGCCCAGA CGGTGGCCAA CTTCAACATC ACCAGTAGCA CCTGTGAGCT CAGTAAGCAA 
CTCAACATCG CCTACGACGT CACCTACAGC CTGGCCTGCG TCCGCTGCTG CGTCAACCCT 
TTCTTGTACG CCTTCATCGG CGTCAAGTTC CGCAACGATC TCTTCAAGCT CTTCAAGGAC 
CTGGGCTGCC TCAGCCAGGA GCAGCTCCGG CAGTGGTCTT CCTGTCGGCA CATCCGGCGC 
TCCTCCATGA GTGTGGAGGC CGAGACCACC ACCACCTTCT CCCCATAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

CCR7 ( NM_001301716.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001288645.1 Homo sapiens C-C motif chemokine receptor 7 (CCR7), transcript variant 3, mRNA.

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CloneID	OHu56954
Clone ID Related Accession (Same CDS sequence)	NM_001301716.1 , NM_001301717.1 , NM_001301718.1
Accession Version	NM_001301716.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1119bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-27
Organism	Homo sapiens(human)
Product	C-C chemokine receptor type 7 isoform c precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AK310277.1 and BC035343.1. Transcript Variant: This variant (3) contains an alternate 5' terminal exon, and it thus differs in its 5' UTR and initiates translation at a downstream in-frame start codon, compared to variant 1. The encoded isoform (c) is shorter at the N-terminus, compared to isoform a. Variants 3, 4 and 5 all encode isoform c. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK310277.1, DB039666.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2148874, SAMEA2151119 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGAAAAGCG TGCTGGTGGT GGCTCTCCTT GTCATTTTCC AGGTATGCCT GTGTCAAGAT 
GAGGTCACGG ACGATTACAT CGGAGACAAC ACCACAGTGG ACTACACTTT GTTCGAGTCT 
TTGTGCTCCA AGAAGGACGT GCGGAACTTT AAAGCCTGGT TCCTCCCTAT CATGTACTCC 
ATCATTTGTT TCGTGGGCCT ACTGGGCAAT GGGCTGGTCG TGTTGACCTA TATCTATTTC 
AAGAGGCTCA AGACCATGAC CGATACCTAC CTGCTCAACC TGGCGGTGGC AGACATCCTC 
TTCCTCCTGA CCCTTCCCTT CTGGGCCTAC AGCGCGGCCA AGTCCTGGGT CTTCGGTGTC 
CACTTTTGCA AGCTCATCTT TGCCATCTAC AAGATGAGCT TCTTCAGTGG CATGCTCCTA 
CTTCTTTGCA TCAGCATTGA CCGCTACGTG GCCATCGTCC AGGCTGTCTC AGCTCACCGC 
CACCGTGCCC GCGTCCTTCT CATCAGCAAG CTGTCCTGTG TGGGCATCTG GATACTAGCC 
ACAGTGCTCT CCATCCCAGA GCTCCTGTAC AGTGACCTCC AGAGGAGCAG CAGTGAGCAA 
GCGATGCGAT GCTCTCTCAT CACAGAGCAT GTGGAGGCCT TTATCACCAT CCAGGTGGCC 
CAGATGGTGA TCGGCTTTCT GGTCCCCCTG CTGGCCATGA GCTTCTGTTA CCTTGTCATC 
ATCCGCACCC TGCTCCAGGC ACGCAACTTT GAGCGCAACA AGGCCATCAA GGTGATCATC 
GCTGTGGTCG TGGTCTTCAT AGTCTTCCAG CTGCCCTACA ATGGGGTGGT CCTGGCCCAG 
ACGGTGGCCA ACTTCAACAT CACCAGTAGC ACCTGTGAGC TCAGTAAGCA ACTCAACATC 
GCCTACGACG TCACCTACAG CCTGGCCTGC GTCCGCTGCT GCGTCAACCC TTTCTTGTAC 
GCCTTCATCG GCGTCAAGTT CCGCAACGAT CTCTTCAAGC TCTTCAAGGA CCTGGGCTGC 
CTCAGCCAGG AGCAGCTCCG GCAGTGGTCT TCCTGTCGGC ACATCCGGCG CTCCTCCATG 
AGTGTGGAGG CCGAGACCAC CACCACCTTC TCCCCATAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001288645.1
CDS	344..1462
Translation	MKSVLVVALLVIFQVCLCQDEVTDDYIGDNTTVDYTLFESLCSKKDVRNFKAWFLPIMYSIICFVGLLGNGLVVLTYIYFKRLKTMTDTYLLNLAVADILFLLTLPFWAYSAAKSWVFGVHFCKLIFAIYKMSFFSGMLLLLCISIDRYVAIVQAVSAHRHRARVLLISKLSCVGIWILATVLSIPELLYSDLQRSSSEQAMRCSLITEHVEAFITIQVAQMVIGFLVPLLAMSFCYLVIIRTLLQARNFERNKAIKVIIAVVVVFIVFQLPYNGVVLAQTVANFNITSSTCELSKQLNIAYDVTYSLACVRCCVNPFLYAFIGVKFRNDLFKLFKDLGCLSQEQLRQWSSCRHIRRSSMSVEAETTTTFSP

Target ORF information:

RefSeq Version	NM_001301716.1
Organism	Homo sapiens(human)
Definition	Homo sapiens C-C motif chemokine receptor 7 (CCR7), transcript variant 3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001301716.1

ORF Insert Sequence:

ATGAAAAGCG TGCTGGTGGT GGCTCTCCTT GTCATTTTCC AGGTATGCCT GTGTCAAGAT 
GAGGTCACGG ACGATTACAT CGGAGACAAC ACCACAGTGG ACTACACTTT GTTCGAGTCT 
TTGTGCTCCA AGAAGGACGT GCGGAACTTT AAAGCCTGGT TCCTCCCTAT CATGTACTCC 
ATCATTTGTT TCGTGGGCCT ACTGGGCAAT GGGCTGGTCG TGTTGACCTA TATCTATTTC 
AAGAGGCTCA AGACCATGAC CGATACCTAC CTGCTCAACC TGGCGGTGGC AGACATCCTC 
TTCCTCCTGA CCCTTCCCTT CTGGGCCTAC AGCGCGGCCA AGTCCTGGGT CTTCGGTGTC 
CACTTTTGCA AGCTCATCTT TGCCATCTAC AAGATGAGCT TCTTCAGTGG CATGCTCCTA 
CTTCTTTGCA TCAGCATTGA CCGCTACGTG GCCATCGTCC AGGCTGTCTC AGCTCACCGC 
CACCGTGCCC GCGTCCTTCT CATCAGCAAG CTGTCCTGTG TGGGCATCTG GATACTAGCC 
ACAGTGCTCT CCATCCCAGA GCTCCTGTAC AGTGACCTCC AGAGGAGCAG CAGTGAGCAA 
GCGATGCGAT GCTCTCTCAT CACAGAGCAT GTGGAGGCCT TTATCACCAT CCAGGTGGCC 
CAGATGGTGA TCGGCTTTCT GGTCCCCCTG CTGGCCATGA GCTTCTGTTA CCTTGTCATC 
ATCCGCACCC TGCTCCAGGC ACGCAACTTT GAGCGCAACA AGGCCATCAA GGTGATCATC 
GCTGTGGTCG TGGTCTTCAT AGTCTTCCAG CTGCCCTACA ATGGGGTGGT CCTGGCCCAG 
ACGGTGGCCA ACTTCAACAT CACCAGTAGC ACCTGTGAGC TCAGTAAGCA ACTCAACATC 
GCCTACGACG TCACCTACAG CCTGGCCTGC GTCCGCTGCT GCGTCAACCC TTTCTTGTAC 
GCCTTCATCG GCGTCAAGTT CCGCAACGAT CTCTTCAAGC TCTTCAAGGA CCTGGGCTGC 
CTCAGCCAGG AGCAGCTCCG GCAGTGGTCT TCCTGTCGGC ACATCCGGCG CTCCTCCATG 
AGTGTGGAGG CCGAGACCAC CACCACCTTC TCCCCATAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

CCR7 ( NM_001301717.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001288646.1 Homo sapiens C-C motif chemokine receptor 7 (CCR7), transcript variant 4, mRNA.

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CloneID	OHu56954
Clone ID Related Accession (Same CDS sequence)	NM_001301716.1 , NM_001301717.1 , NM_001301718.1
Accession Version	NM_001301717.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1119bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-15
Organism	Homo sapiens(human)
Product	C-C chemokine receptor type 7 isoform c precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AK310277.1, HY017993.1 and BC035343.1. Transcript Variant: This variant (4) contains an alternate 5' terminal exon, and it thus differs in its 5' UTR and initiates translation at a downstream in-frame start codon, compared to variant 1. The encoded isoform (c) is shorter at the N-terminus, compared to isoform a. Variants 3, 4 and 5 all encode isoform c. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: HY017993.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2148874, SAMEA2161674 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGAAAAGCG TGCTGGTGGT GGCTCTCCTT GTCATTTTCC AGGTATGCCT GTGTCAAGAT 
GAGGTCACGG ACGATTACAT CGGAGACAAC ACCACAGTGG ACTACACTTT GTTCGAGTCT 
TTGTGCTCCA AGAAGGACGT GCGGAACTTT AAAGCCTGGT TCCTCCCTAT CATGTACTCC 
ATCATTTGTT TCGTGGGCCT ACTGGGCAAT GGGCTGGTCG TGTTGACCTA TATCTATTTC 
AAGAGGCTCA AGACCATGAC CGATACCTAC CTGCTCAACC TGGCGGTGGC AGACATCCTC 
TTCCTCCTGA CCCTTCCCTT CTGGGCCTAC AGCGCGGCCA AGTCCTGGGT CTTCGGTGTC 
CACTTTTGCA AGCTCATCTT TGCCATCTAC AAGATGAGCT TCTTCAGTGG CATGCTCCTA 
CTTCTTTGCA TCAGCATTGA CCGCTACGTG GCCATCGTCC AGGCTGTCTC AGCTCACCGC 
CACCGTGCCC GCGTCCTTCT CATCAGCAAG CTGTCCTGTG TGGGCATCTG GATACTAGCC 
ACAGTGCTCT CCATCCCAGA GCTCCTGTAC AGTGACCTCC AGAGGAGCAG CAGTGAGCAA 
GCGATGCGAT GCTCTCTCAT CACAGAGCAT GTGGAGGCCT TTATCACCAT CCAGGTGGCC 
CAGATGGTGA TCGGCTTTCT GGTCCCCCTG CTGGCCATGA GCTTCTGTTA CCTTGTCATC 
ATCCGCACCC TGCTCCAGGC ACGCAACTTT GAGCGCAACA AGGCCATCAA GGTGATCATC 
GCTGTGGTCG TGGTCTTCAT AGTCTTCCAG CTGCCCTACA ATGGGGTGGT CCTGGCCCAG 
ACGGTGGCCA ACTTCAACAT CACCAGTAGC ACCTGTGAGC TCAGTAAGCA ACTCAACATC 
GCCTACGACG TCACCTACAG CCTGGCCTGC GTCCGCTGCT GCGTCAACCC TTTCTTGTAC 
GCCTTCATCG GCGTCAAGTT CCGCAACGAT CTCTTCAAGC TCTTCAAGGA CCTGGGCTGC 
CTCAGCCAGG AGCAGCTCCG GCAGTGGTCT TCCTGTCGGC ACATCCGGCG CTCCTCCATG 
AGTGTGGAGG CCGAGACCAC CACCACCTTC TCCCCATAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001288646.1
CDS	100..1218
Translation	MKSVLVVALLVIFQVCLCQDEVTDDYIGDNTTVDYTLFESLCSKKDVRNFKAWFLPIMYSIICFVGLLGNGLVVLTYIYFKRLKTMTDTYLLNLAVADILFLLTLPFWAYSAAKSWVFGVHFCKLIFAIYKMSFFSGMLLLLCISIDRYVAIVQAVSAHRHRARVLLISKLSCVGIWILATVLSIPELLYSDLQRSSSEQAMRCSLITEHVEAFITIQVAQMVIGFLVPLLAMSFCYLVIIRTLLQARNFERNKAIKVIIAVVVVFIVFQLPYNGVVLAQTVANFNITSSTCELSKQLNIAYDVTYSLACVRCCVNPFLYAFIGVKFRNDLFKLFKDLGCLSQEQLRQWSSCRHIRRSSMSVEAETTTTFSP

Target ORF information:

RefSeq Version	NM_001301717.1
Organism	Homo sapiens(human)
Definition	Homo sapiens C-C motif chemokine receptor 7 (CCR7), transcript variant 4, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001301717.1

ORF Insert Sequence:

ATGAAAAGCG TGCTGGTGGT GGCTCTCCTT GTCATTTTCC AGGTATGCCT GTGTCAAGAT 
GAGGTCACGG ACGATTACAT CGGAGACAAC ACCACAGTGG ACTACACTTT GTTCGAGTCT 
TTGTGCTCCA AGAAGGACGT GCGGAACTTT AAAGCCTGGT TCCTCCCTAT CATGTACTCC 
ATCATTTGTT TCGTGGGCCT ACTGGGCAAT GGGCTGGTCG TGTTGACCTA TATCTATTTC 
AAGAGGCTCA AGACCATGAC CGATACCTAC CTGCTCAACC TGGCGGTGGC AGACATCCTC 
TTCCTCCTGA CCCTTCCCTT CTGGGCCTAC AGCGCGGCCA AGTCCTGGGT CTTCGGTGTC 
CACTTTTGCA AGCTCATCTT TGCCATCTAC AAGATGAGCT TCTTCAGTGG CATGCTCCTA 
CTTCTTTGCA TCAGCATTGA CCGCTACGTG GCCATCGTCC AGGCTGTCTC AGCTCACCGC 
CACCGTGCCC GCGTCCTTCT CATCAGCAAG CTGTCCTGTG TGGGCATCTG GATACTAGCC 
ACAGTGCTCT CCATCCCAGA GCTCCTGTAC AGTGACCTCC AGAGGAGCAG CAGTGAGCAA 
GCGATGCGAT GCTCTCTCAT CACAGAGCAT GTGGAGGCCT TTATCACCAT CCAGGTGGCC 
CAGATGGTGA TCGGCTTTCT GGTCCCCCTG CTGGCCATGA GCTTCTGTTA CCTTGTCATC 
ATCCGCACCC TGCTCCAGGC ACGCAACTTT GAGCGCAACA AGGCCATCAA GGTGATCATC 
GCTGTGGTCG TGGTCTTCAT AGTCTTCCAG CTGCCCTACA ATGGGGTGGT CCTGGCCCAG 
ACGGTGGCCA ACTTCAACAT CACCAGTAGC ACCTGTGAGC TCAGTAAGCA ACTCAACATC 
GCCTACGACG TCACCTACAG CCTGGCCTGC GTCCGCTGCT GCGTCAACCC TTTCTTGTAC 
GCCTTCATCG GCGTCAAGTT CCGCAACGAT CTCTTCAAGC TCTTCAAGGA CCTGGGCTGC 
CTCAGCCAGG AGCAGCTCCG GCAGTGGTCT TCCTGTCGGC ACATCCGGCG CTCCTCCATG 
AGTGTGGAGG CCGAGACCAC CACCACCTTC TCCCCATAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

CCR7 ( NM_001301718.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001288647.1 Homo sapiens C-C motif chemokine receptor 7 (CCR7), transcript variant 5, mRNA.

Price & Availability↑

CloneID	OHu56954
Clone ID Related Accession (Same CDS sequence)	NM_001301716.1 , NM_001301717.1 , NM_001301718.1
Accession Version	NM_001301718.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1119bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-15
Organism	Homo sapiens(human)
Product	C-C chemokine receptor type 7 isoform c precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from HY021417.1 and BC035343.1. Transcript Variant: This variant (5) contains an alternate 5' terminal exon, and it thus differs in its 5' UTR and initiates translation at a downstream in-frame start codon, compared to variant 1. The encoded isoform (c) is shorter at the N-terminus, compared to isoform a. Variants 3, 4 and 5 all encode isoform c. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: HY021417.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1968968 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGAAAAGCG TGCTGGTGGT GGCTCTCCTT GTCATTTTCC AGGTATGCCT GTGTCAAGAT 
GAGGTCACGG ACGATTACAT CGGAGACAAC ACCACAGTGG ACTACACTTT GTTCGAGTCT 
TTGTGCTCCA AGAAGGACGT GCGGAACTTT AAAGCCTGGT TCCTCCCTAT CATGTACTCC 
ATCATTTGTT TCGTGGGCCT ACTGGGCAAT GGGCTGGTCG TGTTGACCTA TATCTATTTC 
AAGAGGCTCA AGACCATGAC CGATACCTAC CTGCTCAACC TGGCGGTGGC AGACATCCTC 
TTCCTCCTGA CCCTTCCCTT CTGGGCCTAC AGCGCGGCCA AGTCCTGGGT CTTCGGTGTC 
CACTTTTGCA AGCTCATCTT TGCCATCTAC AAGATGAGCT TCTTCAGTGG CATGCTCCTA 
CTTCTTTGCA TCAGCATTGA CCGCTACGTG GCCATCGTCC AGGCTGTCTC AGCTCACCGC 
CACCGTGCCC GCGTCCTTCT CATCAGCAAG CTGTCCTGTG TGGGCATCTG GATACTAGCC 
ACAGTGCTCT CCATCCCAGA GCTCCTGTAC AGTGACCTCC AGAGGAGCAG CAGTGAGCAA 
GCGATGCGAT GCTCTCTCAT CACAGAGCAT GTGGAGGCCT TTATCACCAT CCAGGTGGCC 
CAGATGGTGA TCGGCTTTCT GGTCCCCCTG CTGGCCATGA GCTTCTGTTA CCTTGTCATC 
ATCCGCACCC TGCTCCAGGC ACGCAACTTT GAGCGCAACA AGGCCATCAA GGTGATCATC 
GCTGTGGTCG TGGTCTTCAT AGTCTTCCAG CTGCCCTACA ATGGGGTGGT CCTGGCCCAG 
ACGGTGGCCA ACTTCAACAT CACCAGTAGC ACCTGTGAGC TCAGTAAGCA ACTCAACATC 
GCCTACGACG TCACCTACAG CCTGGCCTGC GTCCGCTGCT GCGTCAACCC TTTCTTGTAC 
GCCTTCATCG GCGTCAAGTT CCGCAACGAT CTCTTCAAGC TCTTCAAGGA CCTGGGCTGC 
CTCAGCCAGG AGCAGCTCCG GCAGTGGTCT TCCTGTCGGC ACATCCGGCG CTCCTCCATG 
AGTGTGGAGG CCGAGACCAC CACCACCTTC TCCCCATAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001288647.1
CDS	190..1308
Translation	MKSVLVVALLVIFQVCLCQDEVTDDYIGDNTTVDYTLFESLCSKKDVRNFKAWFLPIMYSIICFVGLLGNGLVVLTYIYFKRLKTMTDTYLLNLAVADILFLLTLPFWAYSAAKSWVFGVHFCKLIFAIYKMSFFSGMLLLLCISIDRYVAIVQAVSAHRHRARVLLISKLSCVGIWILATVLSIPELLYSDLQRSSSEQAMRCSLITEHVEAFITIQVAQMVIGFLVPLLAMSFCYLVIIRTLLQARNFERNKAIKVIIAVVVVFIVFQLPYNGVVLAQTVANFNITSSTCELSKQLNIAYDVTYSLACVRCCVNPFLYAFIGVKFRNDLFKLFKDLGCLSQEQLRQWSSCRHIRRSSMSVEAETTTTFSP

Target ORF information:

RefSeq Version	NM_001301718.1
Organism	Homo sapiens(human)
Definition	Homo sapiens C-C motif chemokine receptor 7 (CCR7), transcript variant 5, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001301718.1

ORF Insert Sequence:

ATGAAAAGCG TGCTGGTGGT GGCTCTCCTT GTCATTTTCC AGGTATGCCT GTGTCAAGAT 
GAGGTCACGG ACGATTACAT CGGAGACAAC ACCACAGTGG ACTACACTTT GTTCGAGTCT 
TTGTGCTCCA AGAAGGACGT GCGGAACTTT AAAGCCTGGT TCCTCCCTAT CATGTACTCC 
ATCATTTGTT TCGTGGGCCT ACTGGGCAAT GGGCTGGTCG TGTTGACCTA TATCTATTTC 
AAGAGGCTCA AGACCATGAC CGATACCTAC CTGCTCAACC TGGCGGTGGC AGACATCCTC 
TTCCTCCTGA CCCTTCCCTT CTGGGCCTAC AGCGCGGCCA AGTCCTGGGT CTTCGGTGTC 
CACTTTTGCA AGCTCATCTT TGCCATCTAC AAGATGAGCT TCTTCAGTGG CATGCTCCTA 
CTTCTTTGCA TCAGCATTGA CCGCTACGTG GCCATCGTCC AGGCTGTCTC AGCTCACCGC 
CACCGTGCCC GCGTCCTTCT CATCAGCAAG CTGTCCTGTG TGGGCATCTG GATACTAGCC 
ACAGTGCTCT CCATCCCAGA GCTCCTGTAC AGTGACCTCC AGAGGAGCAG CAGTGAGCAA 
GCGATGCGAT GCTCTCTCAT CACAGAGCAT GTGGAGGCCT TTATCACCAT CCAGGTGGCC 
CAGATGGTGA TCGGCTTTCT GGTCCCCCTG CTGGCCATGA GCTTCTGTTA CCTTGTCATC 
ATCCGCACCC TGCTCCAGGC ACGCAACTTT GAGCGCAACA AGGCCATCAA GGTGATCATC 
GCTGTGGTCG TGGTCTTCAT AGTCTTCCAG CTGCCCTACA ATGGGGTGGT CCTGGCCCAG 
ACGGTGGCCA ACTTCAACAT CACCAGTAGC ACCTGTGAGC TCAGTAAGCA ACTCAACATC 
GCCTACGACG TCACCTACAG CCTGGCCTGC GTCCGCTGCT GCGTCAACCC TTTCTTGTAC 
GCCTTCATCG GCGTCAAGTT CCGCAACGAT CTCTTCAAGC TCTTCAAGGA CCTGGGCTGC 
CTCAGCCAGG AGCAGCTCCG GCAGTGGTCT TCCTGTCGGC ACATCCGGCG CTCCTCCATG 
AGTGTGGAGG CCGAGACCAC CACCACCTTC TCCCCATAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

MiR-1275 promotes cell migration, invasion and proliferation in squamous cell carcinoma of head and neck via up-regulating IGF-1R and CCR7.
Gene(2017 Dec)
Liu MD,Wu H,Wang S,Pang P,Jin S,Sun CF,Liu FY

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CCR7 cDNA ORF clone, Homo sapiens(human)

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gRNAs

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Target ORF information:

ORF Insert Sequence:

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Target ORF information:

ORF Insert Sequence:

Target ORF information:

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ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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