TC2N cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	TC2N
Entrez Gene ID	123036
Full Name	tandem C2 domains, nuclear
Synonyms	C14orf47,C2CD1,MTAC2D1,Tac2-N
General protein information	Preferred Names tandem C2 domains, nuclear Names tandem C2 domains nuclear protein C2 calcium-dependent domain containing 1 membrane targeting (tandem) C2 domain containing 1 tandem C2 protein in nucleus
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 14 Map Location: 14q32.12

mRNA and Protein(s)

mRNA	Protein	Name
NM_001128596.2	NP_001122068.1	tandem C2 domains nuclear protein isoform 1
NM_001128595.2	NP_001122067.1	tandem C2 domains nuclear protein isoform 1
NM_001128596.3	NP_001122068.2	tandem C2 domains nuclear protein isoform 1
NM_001289134.2	NP_001276063.2	tandem C2 domains nuclear protein isoform 2
NM_001289134.1	NP_001276063.1	tandem C2 domains nuclear protein isoform 2
NM_001128595.3	NP_001122067.2	tandem C2 domains nuclear protein isoform 1
NM_152332.5	NP_689545.1	tandem C2 domains nuclear protein isoform 1
NM_152332.6	NP_689545.2	tandem C2 domains nuclear protein isoform 1

Pathways from BioSystems

Homologies

Canis lupus familiaris (dog)	TC2N	XP_547711.1
Bos taurus (cattle)	TC2N	NP_001180133.1
Mus musculus (house mouse)	Tc2n	NP_001273293.1
Gallus gallus (chicken)	TC2N	XP_004941928.1
Xenopus tropicalis (tropical clawed frog)	tc2n	XP_002933250.2
Homo sapiens (human)	TC2N	NP_689545.1
	TC2N	XP_001091431.1
Rattus norvegicus (Norway rat)	Tc2n	NP_001020323.1
Pan troglodytes (chimpanzee)	TC2N	XP_001145068.1
Danio rerio (zebrafish)	LOC101885722	XP_005157017.1

Gene Ontology
Bibliography

Related articles in PubMed

Combined analysis of three genome-wide association studies on vWF and FVIII plasma levels.
Antoni G, Oudot-Mellakh T, Dimitromanolakis A, Germain M, Cohen W, Wells P, Lathrop M, Gagnon F, Morange PE, Tregouet DA
BMC medical genetics12102(2011 Aug)

Impact on venous thrombosis risk of newly discovered gene variants associated with FVIII and VWF plasma levels.
Morange PE, Saut N, Antoni G, Emmerich J, Tr?gou?t DA
Journal of thrombosis and haemostasis : JTH9(1)229-31(2011 Jan)

Tac2-N, an atypical C-type tandem C2 protein localized in the nucleus.
Fukuda M, Mikoshiba K
FEBS letters503(2-3)217-8(2001 Aug)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Observational study of gene-disease association. (HuGE Navigator)
Title: Impact on venous thrombosis risk of newly discovered gene variants associated with FVIII and VWF plasma levels.

The following TC2N gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the TC2N cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu11065	NM_001128596.2 Latest version!	Homo sapiens tandem C2 domains, nuclear (TC2N), transcript variant 3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$189.50-$265.30 $379.00
OHu11065	NM_152332.5 Latest version!	Homo sapiens tandem C2 domains, nuclear (TC2N), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$189.50-$265.30 $379.00
OHu11065	NM_001128595.2 Latest version!	Homo sapiens tandem C2 domains, nuclear (TC2N), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$189.50-$265.30 $379.00
OHu10613	NM_001289134.1 Latest version!	Homo sapiens tandem C2 domains, nuclear (TC2N), transcript variant 4, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$223.30 $319.00
OHu107592	NM_001128596.3 Latest version!	Homo sapiens tandem C2 domains, nuclear (TC2N), transcript variant 3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$223.30 $319.00
OHu107592	NM_001128595.3 Latest version!	Homo sapiens tandem C2 domains, nuclear (TC2N), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$223.30 $319.00
OHu107592	NM_152332.6 Latest version!	Homo sapiens tandem C2 domains, nuclear (TC2N), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$223.30 $319.00
OHu108225	NM_001289134.2 Latest version!	Homo sapiens tandem C2 domains, nuclear (TC2N), transcript variant 4, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$223.30 $319.00

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

TC2N ( NM_001128596.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_001122068.1 Homo sapiens tandem C2 domains, nuclear (TC2N), transcript variant 3, mRNA.

Price & Availability↑

CloneID	OHu11065
Clone ID Related Accession (Same CDS sequence)	NM_001128596.2 , NM_001128595.2 , NM_152332.5
Accession Version	NM_001128596.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1473bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-10-02
Organism	Homo sapiens(human)
Product	tandem C2 domains nuclear protein isoform 1
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from DB236967.1, AK093876.1, BC040503.1, BX647828.1 and AL121839.3. On Jan 15, 2014 this sequence version replaced NM_001128596.1. Transcript Variant: This variant (3) represents use of an alternate promoter and differs in the 5' UTR, compared to variant 1. Variants 1, 2, and 3 encode the same isoform (1). Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. ##Evidence-Data-START## Transcript exon combination :: AK093876.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGCAACAG AATTTATAAA GAGTTGCTGT GGAGGATGTT TCTATGGTGA AACAGAAAAA 
CACAACTTTT CTGTGGAAAG AGATTTTAAA GCAGCAGTCC CAAATAGTCA AAATGCTACT 
ATCTCTGTAC CTCCATTGAC TTCTGTTTCT GTAAAGCCTC AGCTTGGCTG TACTGAGGAT 
TATTTGCTTT CCAAATTACC ATCTGATGGC AAAGAAGTAC CATTTGTGGT GCCCAAGTTT 
AAGTTATCTT ACATTCAACC CAGGACACAA GAAACTCCTT CACATCTGGA AGAACTTGAA 
GGATCTGCCA GAGCATCTTT TGGAGATCGA AAGGTAGAAC TTTCCAGTTC ATCCCAGCAC 
GGACCTAGCT ATGATGTGTA TAACCCATTC TATATGTATC AGCACATTTC ACCTGATTTG 
AGTCGACGCT TTCCTCCCCG TTCAGAAGTG ACGAGACTGT ATGGATCGGT TTGTGATTTA 
AGGACGAACA AACTTCCCGG TTCCCCTGGG CTAAGCAAAT CTATGTTTGA TCTTACAAAC 
TCATCTCAGC GATTCATCCA GAGACATGAT TCATTGTCCA GTGTACCCAG TAGTTCTTCT 
TCAAGGAAAA ATTCTCAGGG GAGTAACAGA AGCCTGGATA CAATTACTCT ATCAGGAGAT 
GAAAGGGACT TTGGGAGACT GAATGTGAAA TTGTTTTATA ATTCTTCAGT AGAACAGATC 
TGGATCACAG TTTTACAGTG CAGAGATTTA AGTTGGCCCT CTAGTTATGG AGACACTCCT 
ACTGTTTCTA TAAAAGGAAT ACTTACATTG CCCAAACCAG TGCATTTCAA ATCTTCAGCC 
AAGGAAGGTT CCAACGCTAT TGAATTTATG GAAACGTTTG TATTTGCTAT TAAACTTCAA 
AATCTACAAA CTGTAAGACT TGTATTTAAG ATTCAAACCC AGACTCCCAG GAAGAAAACC 
ATTGGAGAAT GCTCAATGTC ACTCAGAACC CTTAGCACAC AGGAAATGGA TTACTCTTTG 
GATATAACAC CACCTTCAAA AATTTCTGTT TGCCATGCAG AACTTGAATT GGGGACTTGT 
TTTCAAGCAG TAAATAGCAG AATTCAGTTA CAAATTCTTG AGGCACGGTA CCTTCCAAGC 
TCATCAACAC CTCTGACTTT GAGTTTTTTC GTGAAGGTGG GAATGTTTAG CTCGGGAGAG 
TTGATTTATA AGAAAAAGAC ACGCTTACTG AAGGCCTCCA ATGGAAGAGT CAAGTGGGGA 
GAGACTATGA TTTTTCCACT TATACAGAGT GAAAAAGAAA TTGTTTTTCT CATTAAGCTT 
TACAGTCGAA GCTCTGTAAG AAGAAAACAC TTTGTGGGCC AGATTTGGAT AAGTGAAGAC 
AGTAATAACA TTGAAGCAGT GAACCAGTGG AAAGAGACAG TAATAAATCC AGAAAAGGTT 
GTTATCAGGT GGCACAAATT AAATCCATCT TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001122068.1
CDS	332..1804
Translation	MATEFIKSCCGGCFYGETEKHNFSVERDFKAAVPNSQNATISVPPLTSVSVKPQLGCTEDYLLSKLPSDGKEVPFVVPKFKLSYIQPRTQETPSHLEELEGSARASFGDRKVELSSSSQHGPSYDVYNPFYMYQHISPDLSRRFPPRSEVTRLYGSVCDLRTNKLPGSPGLSKSMFDLTNSSQRFIQRHDSLSSVPSSSSSRKNSQGSNRSLDTITLSGDERDFGRLNVKLFYNSSVEQIWITVLQCRDLSWPSSYGDTPTVSIKGILTLPKPVHFKSSAKEGSNAIEFMETFVFAIKLQNLQTVRLVFKIQTQTPRKKTIGECSMSLRTLSTQEMDYSLDITPPSKISVCHAELELGTCFQAVNSRIQLQILEARYLPSSSTPLTLSFFVKVGMFSSGELIYKKKTRLLKASNGRVKWGETMIFPLIQSEKEIVFLIKLYSRSSVRRKHFVGQIWISEDSNNIEAVNQWKETVINPEKVVIRWHKLNPS

Target ORF information:

RefSeq Version	NM_001128596.2
Organism	Homo sapiens(human)
Definition	Homo sapiens tandem C2 domains, nuclear (TC2N), transcript variant 3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001128596.2

ORF Insert Sequence:

ATGGCAACAG AATTTATAAA GAGTTGCTGT GGAGGATGTT TCTATGGTGA AACAGAAAAA 
CACAACTTTT CTGTGGAAAG AGATTTTAAA GCAGCAGTCC CAAATAGTCA AAATGCTACT 
ATCTCTGTAC CTCCATTGAC TTCTGTTTCT GTAAAGCCTC AGCTTGGCTG TACTGAGGAT 
TATTTGCTTT CCAAATTACC ATCTGATGGC AAAGAAGTAC CATTTGTGGT GCCCAAGTTT 
AAGTTATCTT ACATTCAACC CAGGACACAA GAAACTCCTT CACATCTGGA AGAACTTGAA 
GGATCTGCCA GAGCATCTTT TGGAGATCGA AAGGTAGAAC TTTCCAGTTC ATCCCAGCAC 
GGACCTAGCT ATGATGTGTA TAACCCATTC TATATGTATC AGCACATTTC ACCTGATTTG 
AGTCGACGCT TTCCTCCCCG TTCAGAAGTG ACGAGACTGT ATGGATCGGT TTGTGATTTA 
AGGACGAACA AACTTCCCGG TTCCCCTGGG CTAAGCAAAT CTATGTTTGA TCTTACAAAC 
TCATCTCAGC GATTCATCCA GAGACATGAT TCATTGTCCA GTGTACCCAG TAGTTCTTCT 
TCAAGGAAAA ATTCTCAGGG GAGTAACAGA AGCCTGGATA CAATTACTCT ATCAGGAGAT 
GAAAGGGACT TTGGGAGACT GAATGTGAAA TTGTTTTATA ATTCTTCAGT AGAACAGATC 
TGGATCACAG TTTTACAGTG CAGAGATTTA AGTTGGCCCT CTAGTTATGG AGACACTCCT 
ACTGTTTCTA TAAAAGGAAT ACTTACATTG CCCAAACCAG TGCATTTCAA ATCTTCAGCC 
AAGGAAGGTT CCAACGCTAT TGAATTTATG GAAACGTTTG TATTTGCTAT TAAACTTCAA 
AATCTACAAA CTGTAAGACT TGTATTTAAG ATTCAAACCC AGACTCCCAG GAAGAAAACC 
ATTGGAGAAT GCTCAATGTC ACTCAGAACC CTTAGCACAC AGGAAATGGA TTACTCTTTG 
GATATAACAC CACCTTCAAA AATTTCTGTT TGCCATGCAG AACTTGAATT GGGGACTTGT 
TTTCAAGCAG TAAATAGCAG AATTCAGTTA CAAATTCTTG AGGCACGGTA CCTTCCAAGC 
TCATCAACAC CTCTGACTTT GAGTTTTTTC GTGAAGGTGG GAATGTTTAG CTCGGGAGAG 
TTGATTTATA AGAAAAAGAC ACGCTTACTG AAGGCCTCCA ATGGAAGAGT CAAGTGGGGA 
GAGACTATGA TTTTTCCACT TATACAGAGT GAAAAAGAAA TTGTTTTTCT CATTAAGCTT 
TACAGTCGAA GCTCTGTAAG AAGAAAACAC TTTGTGGGCC AGATTTGGAT AAGTGAAGAC 
AGTAATAACA TTGAAGCAGT GAACCAGTGG AAAGAGACAG TAATAAATCC AGAAAAGGTT 
GTTATCAGGT GGCACAAATT AAATCCATCT TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

TC2N ( NM_001128595.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_001122067.1 Homo sapiens tandem C2 domains, nuclear (TC2N), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu11065
Clone ID Related Accession (Same CDS sequence)	NM_001128596.2 , NM_001128595.2 , NM_152332.5
Accession Version	NM_001128595.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1473bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-02-23
Organism	Homo sapiens(human)
Product	tandem C2 domains nuclear protein isoform 1
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BI547572.1, DB215118.1, BC040503.1, BX647828.1 and AL121839.3. On Jan 15, 2014 this sequence version replaced NM_001128595.1. Transcript Variant: This variant (2) uses an alternate splice site in the 5' UTR, compared to variant 1. Variants 1, 2, and 3 encode the same isoform (1). Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. ##Evidence-Data-START## Transcript exon combination :: BX647828.1, ERR279857.2211.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGCAACAG AATTTATAAA GAGTTGCTGT GGAGGATGTT TCTATGGTGA AACAGAAAAA 
CACAACTTTT CTGTGGAAAG AGATTTTAAA GCAGCAGTCC CAAATAGTCA AAATGCTACT 
ATCTCTGTAC CTCCATTGAC TTCTGTTTCT GTAAAGCCTC AGCTTGGCTG TACTGAGGAT 
TATTTGCTTT CCAAATTACC ATCTGATGGC AAAGAAGTAC CATTTGTGGT GCCCAAGTTT 
AAGTTATCTT ACATTCAACC CAGGACACAA GAAACTCCTT CACATCTGGA AGAACTTGAA 
GGATCTGCCA GAGCATCTTT TGGAGATCGA AAGGTAGAAC TTTCCAGTTC ATCCCAGCAC 
GGACCTAGCT ATGATGTGTA TAACCCATTC TATATGTATC AGCACATTTC ACCTGATTTG 
AGTCGACGCT TTCCTCCCCG TTCAGAAGTG ACGAGACTGT ATGGATCGGT TTGTGATTTA 
AGGACGAACA AACTTCCCGG TTCCCCTGGG CTAAGCAAAT CTATGTTTGA TCTTACAAAC 
TCATCTCAGC GATTCATCCA GAGACATGAT TCATTGTCCA GTGTACCCAG TAGTTCTTCT 
TCAAGGAAAA ATTCTCAGGG GAGTAACAGA AGCCTGGATA CAATTACTCT ATCAGGAGAT 
GAAAGGGACT TTGGGAGACT GAATGTGAAA TTGTTTTATA ATTCTTCAGT AGAACAGATC 
TGGATCACAG TTTTACAGTG CAGAGATTTA AGTTGGCCCT CTAGTTATGG AGACACTCCT 
ACTGTTTCTA TAAAAGGAAT ACTTACATTG CCCAAACCAG TGCATTTCAA ATCTTCAGCC 
AAGGAAGGTT CCAACGCTAT TGAATTTATG GAAACGTTTG TATTTGCTAT TAAACTTCAA 
AATCTACAAA CTGTAAGACT TGTATTTAAG ATTCAAACCC AGACTCCCAG GAAGAAAACC 
ATTGGAGAAT GCTCAATGTC ACTCAGAACC CTTAGCACAC AGGAAATGGA TTACTCTTTG 
GATATAACAC CACCTTCAAA AATTTCTGTT TGCCATGCAG AACTTGAATT GGGGACTTGT 
TTTCAAGCAG TAAATAGCAG AATTCAGTTA CAAATTCTTG AGGCACGGTA CCTTCCAAGC 
TCATCAACAC CTCTGACTTT GAGTTTTTTC GTGAAGGTGG GAATGTTTAG CTCGGGAGAG 
TTGATTTATA AGAAAAAGAC ACGCTTACTG AAGGCCTCCA ATGGAAGAGT CAAGTGGGGA 
GAGACTATGA TTTTTCCACT TATACAGAGT GAAAAAGAAA TTGTTTTTCT CATTAAGCTT 
TACAGTCGAA GCTCTGTAAG AAGAAAACAC TTTGTGGGCC AGATTTGGAT AAGTGAAGAC 
AGTAATAACA TTGAAGCAGT GAACCAGTGG AAAGAGACAG TAATAAATCC AGAAAAGGTT 
GTTATCAGGT GGCACAAATT AAATCCATCT TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001122067.1
CDS	213..1685
Translation	MATEFIKSCCGGCFYGETEKHNFSVERDFKAAVPNSQNATISVPPLTSVSVKPQLGCTEDYLLSKLPSDGKEVPFVVPKFKLSYIQPRTQETPSHLEELEGSARASFGDRKVELSSSSQHGPSYDVYNPFYMYQHISPDLSRRFPPRSEVTRLYGSVCDLRTNKLPGSPGLSKSMFDLTNSSQRFIQRHDSLSSVPSSSSSRKNSQGSNRSLDTITLSGDERDFGRLNVKLFYNSSVEQIWITVLQCRDLSWPSSYGDTPTVSIKGILTLPKPVHFKSSAKEGSNAIEFMETFVFAIKLQNLQTVRLVFKIQTQTPRKKTIGECSMSLRTLSTQEMDYSLDITPPSKISVCHAELELGTCFQAVNSRIQLQILEARYLPSSSTPLTLSFFVKVGMFSSGELIYKKKTRLLKASNGRVKWGETMIFPLIQSEKEIVFLIKLYSRSSVRRKHFVGQIWISEDSNNIEAVNQWKETVINPEKVVIRWHKLNPS

Target ORF information:

RefSeq Version	NM_001128595.2
Organism	Homo sapiens(human)
Definition	Homo sapiens tandem C2 domains, nuclear (TC2N), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001128595.2

ORF Insert Sequence:

ATGGCAACAG AATTTATAAA GAGTTGCTGT GGAGGATGTT TCTATGGTGA AACAGAAAAA 
CACAACTTTT CTGTGGAAAG AGATTTTAAA GCAGCAGTCC CAAATAGTCA AAATGCTACT 
ATCTCTGTAC CTCCATTGAC TTCTGTTTCT GTAAAGCCTC AGCTTGGCTG TACTGAGGAT 
TATTTGCTTT CCAAATTACC ATCTGATGGC AAAGAAGTAC CATTTGTGGT GCCCAAGTTT 
AAGTTATCTT ACATTCAACC CAGGACACAA GAAACTCCTT CACATCTGGA AGAACTTGAA 
GGATCTGCCA GAGCATCTTT TGGAGATCGA AAGGTAGAAC TTTCCAGTTC ATCCCAGCAC 
GGACCTAGCT ATGATGTGTA TAACCCATTC TATATGTATC AGCACATTTC ACCTGATTTG 
AGTCGACGCT TTCCTCCCCG TTCAGAAGTG ACGAGACTGT ATGGATCGGT TTGTGATTTA 
AGGACGAACA AACTTCCCGG TTCCCCTGGG CTAAGCAAAT CTATGTTTGA TCTTACAAAC 
TCATCTCAGC GATTCATCCA GAGACATGAT TCATTGTCCA GTGTACCCAG TAGTTCTTCT 
TCAAGGAAAA ATTCTCAGGG GAGTAACAGA AGCCTGGATA CAATTACTCT ATCAGGAGAT 
GAAAGGGACT TTGGGAGACT GAATGTGAAA TTGTTTTATA ATTCTTCAGT AGAACAGATC 
TGGATCACAG TTTTACAGTG CAGAGATTTA AGTTGGCCCT CTAGTTATGG AGACACTCCT 
ACTGTTTCTA TAAAAGGAAT ACTTACATTG CCCAAACCAG TGCATTTCAA ATCTTCAGCC 
AAGGAAGGTT CCAACGCTAT TGAATTTATG GAAACGTTTG TATTTGCTAT TAAACTTCAA 
AATCTACAAA CTGTAAGACT TGTATTTAAG ATTCAAACCC AGACTCCCAG GAAGAAAACC 
ATTGGAGAAT GCTCAATGTC ACTCAGAACC CTTAGCACAC AGGAAATGGA TTACTCTTTG 
GATATAACAC CACCTTCAAA AATTTCTGTT TGCCATGCAG AACTTGAATT GGGGACTTGT 
TTTCAAGCAG TAAATAGCAG AATTCAGTTA CAAATTCTTG AGGCACGGTA CCTTCCAAGC 
TCATCAACAC CTCTGACTTT GAGTTTTTTC GTGAAGGTGG GAATGTTTAG CTCGGGAGAG 
TTGATTTATA AGAAAAAGAC ACGCTTACTG AAGGCCTCCA ATGGAAGAGT CAAGTGGGGA 
GAGACTATGA TTTTTCCACT TATACAGAGT GAAAAAGAAA TTGTTTTTCT CATTAAGCTT 
TACAGTCGAA GCTCTGTAAG AAGAAAACAC TTTGTGGGCC AGATTTGGAT AAGTGAAGAC 
AGTAATAACA TTGAAGCAGT GAACCAGTGG AAAGAGACAG TAATAAATCC AGAAAAGGTT 
GTTATCAGGT GGCACAAATT AAATCCATCT TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

TC2N ( NM_152332.5 ) cDNA ORF clone, Homo sapiens(human) -> NP_689545.1 Homo sapiens tandem C2 domains, nuclear (TC2N), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu11065
Clone ID Related Accession (Same CDS sequence)	NM_001128596.2 , NM_001128595.2 , NM_152332.5
Accession Version	NM_152332.5 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1473bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-02-23
Organism	Homo sapiens(human)
Product	tandem C2 domains nuclear protein isoform 1
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BI547572.1, DB215118.1, AW275132.1, AL121839.3, BC040503.1 and BX647828.1. On Jan 15, 2014 this sequence version replaced NM_152332.4. Transcript Variant: This variant (1) represents the longest transcript and encodes the longer isoform (1). Variants 1, 2, and 3 encode the same isoform (1). Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. ##Evidence-Data-START## Transcript exon combination :: BC040503.1, SRR1803612.33162.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGCAACAG AATTTATAAA GAGTTGCTGT GGAGGATGTT TCTATGGTGA AACAGAAAAA 
CACAACTTTT CTGTGGAAAG AGATTTTAAA GCAGCAGTCC CAAATAGTCA AAATGCTACT 
ATCTCTGTAC CTCCATTGAC TTCTGTTTCT GTAAAGCCTC AGCTTGGCTG TACTGAGGAT 
TATTTGCTTT CCAAATTACC ATCTGATGGC AAAGAAGTAC CATTTGTGGT GCCCAAGTTT 
AAGTTATCTT ACATTCAACC CAGGACACAA GAAACTCCTT CACATCTGGA AGAACTTGAA 
GGATCTGCCA GAGCATCTTT TGGAGATCGA AAGGTAGAAC TTTCCAGTTC ATCCCAGCAC 
GGACCTAGCT ATGATGTGTA TAACCCATTC TATATGTATC AGCACATTTC ACCTGATTTG 
AGTCGACGCT TTCCTCCCCG TTCAGAAGTG ACGAGACTGT ATGGATCGGT TTGTGATTTA 
AGGACGAACA AACTTCCCGG TTCCCCTGGG CTAAGCAAAT CTATGTTTGA TCTTACAAAC 
TCATCTCAGC GATTCATCCA GAGACATGAT TCATTGTCCA GTGTACCCAG TAGTTCTTCT 
TCAAGGAAAA ATTCTCAGGG GAGTAACAGA AGCCTGGATA CAATTACTCT ATCAGGAGAT 
GAAAGGGACT TTGGGAGACT GAATGTGAAA TTGTTTTATA ATTCTTCAGT AGAACAGATC 
TGGATCACAG TTTTACAGTG CAGAGATTTA AGTTGGCCCT CTAGTTATGG AGACACTCCT 
ACTGTTTCTA TAAAAGGAAT ACTTACATTG CCCAAACCAG TGCATTTCAA ATCTTCAGCC 
AAGGAAGGTT CCAACGCTAT TGAATTTATG GAAACGTTTG TATTTGCTAT TAAACTTCAA 
AATCTACAAA CTGTAAGACT TGTATTTAAG ATTCAAACCC AGACTCCCAG GAAGAAAACC 
ATTGGAGAAT GCTCAATGTC ACTCAGAACC CTTAGCACAC AGGAAATGGA TTACTCTTTG 
GATATAACAC CACCTTCAAA AATTTCTGTT TGCCATGCAG AACTTGAATT GGGGACTTGT 
TTTCAAGCAG TAAATAGCAG AATTCAGTTA CAAATTCTTG AGGCACGGTA CCTTCCAAGC 
TCATCAACAC CTCTGACTTT GAGTTTTTTC GTGAAGGTGG GAATGTTTAG CTCGGGAGAG 
TTGATTTATA AGAAAAAGAC ACGCTTACTG AAGGCCTCCA ATGGAAGAGT CAAGTGGGGA 
GAGACTATGA TTTTTCCACT TATACAGAGT GAAAAAGAAA TTGTTTTTCT CATTAAGCTT 
TACAGTCGAA GCTCTGTAAG AAGAAAACAC TTTGTGGGCC AGATTTGGAT AAGTGAAGAC 
AGTAATAACA TTGAAGCAGT GAACCAGTGG AAAGAGACAG TAATAAATCC AGAAAAGGTT 
GTTATCAGGT GGCACAAATT AAATCCATCT TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_689545.1
CDS	401..1873
Translation	MATEFIKSCCGGCFYGETEKHNFSVERDFKAAVPNSQNATISVPPLTSVSVKPQLGCTEDYLLSKLPSDGKEVPFVVPKFKLSYIQPRTQETPSHLEELEGSARASFGDRKVELSSSSQHGPSYDVYNPFYMYQHISPDLSRRFPPRSEVTRLYGSVCDLRTNKLPGSPGLSKSMFDLTNSSQRFIQRHDSLSSVPSSSSSRKNSQGSNRSLDTITLSGDERDFGRLNVKLFYNSSVEQIWITVLQCRDLSWPSSYGDTPTVSIKGILTLPKPVHFKSSAKEGSNAIEFMETFVFAIKLQNLQTVRLVFKIQTQTPRKKTIGECSMSLRTLSTQEMDYSLDITPPSKISVCHAELELGTCFQAVNSRIQLQILEARYLPSSSTPLTLSFFVKVGMFSSGELIYKKKTRLLKASNGRVKWGETMIFPLIQSEKEIVFLIKLYSRSSVRRKHFVGQIWISEDSNNIEAVNQWKETVINPEKVVIRWHKLNPS

Target ORF information:

RefSeq Version	NM_152332.5
Organism	Homo sapiens(human)
Definition	Homo sapiens tandem C2 domains, nuclear (TC2N), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_152332.5

ORF Insert Sequence:

ATGGCAACAG AATTTATAAA GAGTTGCTGT GGAGGATGTT TCTATGGTGA AACAGAAAAA 
CACAACTTTT CTGTGGAAAG AGATTTTAAA GCAGCAGTCC CAAATAGTCA AAATGCTACT 
ATCTCTGTAC CTCCATTGAC TTCTGTTTCT GTAAAGCCTC AGCTTGGCTG TACTGAGGAT 
TATTTGCTTT CCAAATTACC ATCTGATGGC AAAGAAGTAC CATTTGTGGT GCCCAAGTTT 
AAGTTATCTT ACATTCAACC CAGGACACAA GAAACTCCTT CACATCTGGA AGAACTTGAA 
GGATCTGCCA GAGCATCTTT TGGAGATCGA AAGGTAGAAC TTTCCAGTTC ATCCCAGCAC 
GGACCTAGCT ATGATGTGTA TAACCCATTC TATATGTATC AGCACATTTC ACCTGATTTG 
AGTCGACGCT TTCCTCCCCG TTCAGAAGTG ACGAGACTGT ATGGATCGGT TTGTGATTTA 
AGGACGAACA AACTTCCCGG TTCCCCTGGG CTAAGCAAAT CTATGTTTGA TCTTACAAAC 
TCATCTCAGC GATTCATCCA GAGACATGAT TCATTGTCCA GTGTACCCAG TAGTTCTTCT 
TCAAGGAAAA ATTCTCAGGG GAGTAACAGA AGCCTGGATA CAATTACTCT ATCAGGAGAT 
GAAAGGGACT TTGGGAGACT GAATGTGAAA TTGTTTTATA ATTCTTCAGT AGAACAGATC 
TGGATCACAG TTTTACAGTG CAGAGATTTA AGTTGGCCCT CTAGTTATGG AGACACTCCT 
ACTGTTTCTA TAAAAGGAAT ACTTACATTG CCCAAACCAG TGCATTTCAA ATCTTCAGCC 
AAGGAAGGTT CCAACGCTAT TGAATTTATG GAAACGTTTG TATTTGCTAT TAAACTTCAA 
AATCTACAAA CTGTAAGACT TGTATTTAAG ATTCAAACCC AGACTCCCAG GAAGAAAACC 
ATTGGAGAAT GCTCAATGTC ACTCAGAACC CTTAGCACAC AGGAAATGGA TTACTCTTTG 
GATATAACAC CACCTTCAAA AATTTCTGTT TGCCATGCAG AACTTGAATT GGGGACTTGT 
TTTCAAGCAG TAAATAGCAG AATTCAGTTA CAAATTCTTG AGGCACGGTA CCTTCCAAGC 
TCATCAACAC CTCTGACTTT GAGTTTTTTC GTGAAGGTGG GAATGTTTAG CTCGGGAGAG 
TTGATTTATA AGAAAAAGAC ACGCTTACTG AAGGCCTCCA ATGGAAGAGT CAAGTGGGGA 
GAGACTATGA TTTTTCCACT TATACAGAGT GAAAAAGAAA TTGTTTTTCT CATTAAGCTT 
TACAGTCGAA GCTCTGTAAG AAGAAAACAC TTTGTGGGCC AGATTTGGAT AAGTGAAGAC 
AGTAATAACA TTGAAGCAGT GAACCAGTGG AAAGAGACAG TAATAAATCC AGAAAAGGTT 
GTTATCAGGT GGCACAAATT AAATCCATCT TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

TC2N ( NM_001289134.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001276063.1 Homo sapiens tandem C2 domains, nuclear (TC2N), transcript variant 4, mRNA.

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CloneID	OHu10613
Clone ID Related Accession (Same CDS sequence)	NM_001289134.1
Accession Version	NM_001289134.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1281bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-02-23
Organism	Homo sapiens(human)
Product	tandem C2 domains nuclear protein isoform 2
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BI547572.1, AK126359.1, BC040503.1, BX647828.1 and AL121839.3. On Jan 15, 2014 this sequence version replaced XM_005267340.1. Transcript Variant: This variant (4) uses an alternate splice site in the 5' UTR and lacks an alternate in-frame exon, compared to variant 1. The encoded isoform (2) is shorter than isoform 1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. ##Evidence-Data-START## Transcript exon combination :: AK126359.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGCAACAG AATTTATAAA GAGTTGCTGT GGAGGATGTT TCTATGGTGA AACAGAAAAA 
CACAACTTTT CTGTGGAAAG AGATTTTAAA GCAGCAGTCC CAAATAGTCA AAATGCTACT 
ATCTCTGTAC CTCCATTGAC TTCTGTTTCT GTAAAGCCTC AGCTTGGCTG TACTGAGGAT 
TATTTGCTTT CCAAATTACC ATCTGATGGC AAAGAAGTAC CATTTGTGGT GCCCAAGTTT 
AAGTTATCTT ACATTCAACC CAGGACACAA GAAACTCCTT CACATCTGGA AGAACTTGAA 
GGATCTGCCA GAGCATCTTT TGGAGATCGA AAGGTAGAAC TTTCCAGTTC ATCCCAGCAC 
GGACCTAGCT ATGATGTGTA TAACCCATTC TATATGTATC AGCACATTTC ACCTGATTTG 
AGTCGACGCT TTCCTCCCCG TTCAGAAGTG ACGAGACTGT ATGGATCGGT TTGTGATTTA 
AGGACGAACA AACTTCCCGG TTCCCCTGGG CTAAGCAAAT CTATGTTTGA TCTTACAAAC 
TCATCTCAGC GATTCATCCA GAGACATGAT TCATTGTCCA GTGTACCCAG TAGTTCTTCT 
TCAAGGAAAA ATTCTCAGGG GAGTAACAGA AGCCTGGATA CAATTACTCT ATCAGGAGAT 
GAAAGGGACT TTGGGAGACT GAATGTGAAA TTGTTTTATA ATTCTTCAGT AGAACAGATC 
TGGATCACAG TTTTACAGTG CAGAGATTTA AGTTGGCCCT CTAGTTATGG AGACACTCCT 
ACTGTTTCTA TAAAAGGAAT ACTTACATTG CCCAAACCAG TGCATTTCAA ATCTTCAGCC 
AAGGAAGGTT CCAACGTTTG CCATGCAGAA CTTGAATTGG GGACTTGTTT TCAAGCAGTA 
AATAGCAGAA TTCAGTTACA AATTCTTGAG GCACGGTACC TTCCAAGCTC ATCAACACCT 
CTGACTTTGA GTTTTTTCGT GAAGGTGGGA ATGTTTAGCT CGGGAGAGTT GATTTATAAG 
AAAAAGACAC GCTTACTGAA GGCCTCCAAT GGAAGAGTCA AGTGGGGAGA GACTATGATT 
TTTCCACTTA TACAGAGTGA AAAAGAAATT GTTTTTCTCA TTAAGCTTTA CAGTCGAAGC 
TCTGTAAGAA GAAAACACTT TGTGGGCCAG ATTTGGATAA GTGAAGACAG TAATAACATT 
GAAGCAGTGA ACCAGTGGAA AGAGACAGTA ATAAATCCAG AAAAGGTTGT TATCAGGTGG 
CACAAATTAA ATCCATCTTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001276063.1
CDS	213..1493
Translation	MATEFIKSCCGGCFYGETEKHNFSVERDFKAAVPNSQNATISVPPLTSVSVKPQLGCTEDYLLSKLPSDGKEVPFVVPKFKLSYIQPRTQETPSHLEELEGSARASFGDRKVELSSSSQHGPSYDVYNPFYMYQHISPDLSRRFPPRSEVTRLYGSVCDLRTNKLPGSPGLSKSMFDLTNSSQRFIQRHDSLSSVPSSSSSRKNSQGSNRSLDTITLSGDERDFGRLNVKLFYNSSVEQIWITVLQCRDLSWPSSYGDTPTVSIKGILTLPKPVHFKSSAKEGSNVCHAELELGTCFQAVNSRIQLQILEARYLPSSSTPLTLSFFVKVGMFSSGELIYKKKTRLLKASNGRVKWGETMIFPLIQSEKEIVFLIKLYSRSSVRRKHFVGQIWISEDSNNIEAVNQWKETVINPEKVVIRWHKLNPS

Target ORF information:

RefSeq Version	NM_001289134.1
Organism	Homo sapiens(human)
Definition	Homo sapiens tandem C2 domains, nuclear (TC2N), transcript variant 4, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001289134.1

ORF Insert Sequence:

ATGGCAACAG AATTTATAAA GAGTTGCTGT GGAGGATGTT TCTATGGTGA AACAGAAAAA 
CACAACTTTT CTGTGGAAAG AGATTTTAAA GCAGCAGTCC CAAATAGTCA AAATGCTACT 
ATCTCTGTAC CTCCATTGAC TTCTGTTTCT GTAAAGCCTC AGCTTGGCTG TACTGAGGAT 
TATTTGCTTT CCAAATTACC ATCTGATGGC AAAGAAGTAC CATTTGTGGT GCCCAAGTTT 
AAGTTATCTT ACATTCAACC CAGGACACAA GAAACTCCTT CACATCTGGA AGAACTTGAA 
GGATCTGCCA GAGCATCTTT TGGAGATCGA AAGGTAGAAC TTTCCAGTTC ATCCCAGCAC 
GGACCTAGCT ATGATGTGTA TAACCCATTC TATATGTATC AGCACATTTC ACCTGATTTG 
AGTCGACGCT TTCCTCCCCG TTCAGAAGTG ACGAGACTGT ATGGATCGGT TTGTGATTTA 
AGGACGAACA AACTTCCCGG TTCCCCTGGG CTAAGCAAAT CTATGTTTGA TCTTACAAAC 
TCATCTCAGC GATTCATCCA GAGACATGAT TCATTGTCCA GTGTACCCAG TAGTTCTTCT 
TCAAGGAAAA ATTCTCAGGG GAGTAACAGA AGCCTGGATA CAATTACTCT ATCAGGAGAT 
GAAAGGGACT TTGGGAGACT GAATGTGAAA TTGTTTTATA ATTCTTCAGT AGAACAGATC 
TGGATCACAG TTTTACAGTG CAGAGATTTA AGTTGGCCCT CTAGTTATGG AGACACTCCT 
ACTGTTTCTA TAAAAGGAAT ACTTACATTG CCCAAACCAG TGCATTTCAA ATCTTCAGCC 
AAGGAAGGTT CCAACGTTTG CCATGCAGAA CTTGAATTGG GGACTTGTTT TCAAGCAGTA 
AATAGCAGAA TTCAGTTACA AATTCTTGAG GCACGGTACC TTCCAAGCTC ATCAACACCT 
CTGACTTTGA GTTTTTTCGT GAAGGTGGGA ATGTTTAGCT CGGGAGAGTT GATTTATAAG 
AAAAAGACAC GCTTACTGAA GGCCTCCAAT GGAAGAGTCA AGTGGGGAGA GACTATGATT 
TTTCCACTTA TACAGAGTGA AAAAGAAATT GTTTTTCTCA TTAAGCTTTA CAGTCGAAGC 
TCTGTAAGAA GAAAACACTT TGTGGGCCAG ATTTGGATAA GTGAAGACAG TAATAACATT 
GAAGCAGTGA ACCAGTGGAA AGAGACAGTA ATAAATCCAG AAAAGGTTGT TATCAGGTGG 
CACAAATTAA ATCCATCTTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

TC2N ( NM_001128596.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_001122068.2 Homo sapiens tandem C2 domains, nuclear (TC2N), transcript variant 3, mRNA.

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CloneID	OHu107592
Clone ID Related Accession (Same CDS sequence)	NM_001128596.3 , NM_001128595.3 , NM_152332.6
Accession Version	NM_001128596.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1473bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-08-06
Organism	Homo sapiens(human)
Product	tandem C2 domains nuclear protein isoform 1
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AL590328.2 and AL121839.3. On Nov 22, 2018 this sequence version replaced NM_001128596.2. Transcript Variant: This variant (3) represents use of an alternate promoter and differs in the 5' UTR, compared to variant 1. Variants 1, 2, and 3 encode the same isoform (1). Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. ##Evidence-Data-START## Transcript exon combination :: AK093876.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000435962.7/ ENSP00000387882.2 RefSeq Select criteria :: based on conservation, expression, longest protein ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGGCAACAG AATTTATAAA GAGTTGCTGT GGAGGATGTT TCTATGGTGA AACAGAAAAA 
CACAACTTTT CTGTGGAAAG AGATTTTAAA GCAGCAGTCC CAAATAGTCA AAATGCTACT 
ATCTCTGTAC CTCCATTGAC TTCTGTTTCT GTAAAGCCTC AGCTTGGCTG TACTGAGGAT 
TATTTGCTTT CCAAATTACC ATCTGATGGC AAAGAAGTAC CATTTGTGGT GCCCAAGTTT 
AAGTTATCTT ACATTCAACC CAGGACACAA GAAACTCCTT CACATCTGGA AGAACTTGAA 
GGATCTGCCA GAGCATCTTT TGGAGATCGA AAGGTAGAAC TTTCCAGTTC ATCCCAGCAC 
GGACCTAGCT ATGATGTGTA TAACCCATTC TATATGTATC AGCACATTTC ACCTGATTTG 
AGTCGACGCT TTCCTCCCCG TTCAGAAGTG AAGAGACTGT ATGGATCGGT TTGTGATTTA 
AGGACGAACA AACTTCCCGG TTCCCCTGGG CTAAGCAAAT CTATGTTTGA TCTTACAAAC 
TCATCTCAGC GATTCATCCA GAGACATGAT TCATTGTCCA GTGTACCCAG TAGTTCTTCT 
TCAAGGAAAA ATTCTCAGGG GAGTAACAGA AGCCTGGATA CAATTACTCT ATCAGGAGAT 
GAAAGGGACT TTGGGAGACT GAATGTGAAA TTGTTTTATA ATTCTTCAGT AGAACAGATC 
TGGATCACAG TTTTACAGTG CAGAGATTTA AGTTGGCCCT CTAGTTATGG AGACACTCCT 
ACTGTTTCTA TAAAAGGAAT ACTTACATTG CCCAAACCAG TGCATTTCAA ATCTTCAGCC 
AAGGAAGGTT CCAACGCTAT TGAATTTATG GAAACGTTTG TATTTGCTAT TAAACTTCAA 
AATCTACAAA CTGTAAGACT TGTATTTAAG ATTCAAACCC AGACTCCCAG GAAGAAAACC 
ATTGGAGAAT GCTCAATGTC ACTCAGAACC CTTAGCACAC AGGAAATGGA TTACTCTTTG 
GATATAACAC CACCTTCAAA AATTTCTGTT TGCCATGCAG AACTTGAATT GGGGACTTGT 
TTTCAAGCAG TAAATAGCAG AATTCAGTTA CAAATTCTTG AGGCACGGTA CCTTCCAAGC 
TCATCAACAC CTCTGACTTT GAGTTTTTTC GTGAAGGTGG GAATGTTTAG CTCGGGAGAG 
TTGATTTATA AGAAAAAGAC ACGCTTACTG AAGGCCTCCA ATGGAAGAGT CAAGTGGGGA 
GAGACTATGA TTTTTCCACT TATACAGAGT GAAAAAGAAA TTGTTTTTCT CATTAAGCTT 
TACAGTCGAA GCTCTGTAAG AAGAAAACAC TTTGTGGGCC AGATTTGGAT AAGTGAAGAC 
AGTAATAACA TTGAAGCAGT GAACCAGTGG AAAGAGACAG TAATAAATCC AGAAAAGGTT 
GTTATCAGGT GGCACAAATT AAATCCATCT TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001122068.2
CDS	332..1804
Translation	MATEFIKSCCGGCFYGETEKHNFSVERDFKAAVPNSQNATISVPPLTSVSVKPQLGCTEDYLLSKLPSDGKEVPFVVPKFKLSYIQPRTQETPSHLEELEGSARASFGDRKVELSSSSQHGPSYDVYNPFYMYQHISPDLSRRFPPRSEVKRLYGSVCDLRTNKLPGSPGLSKSMFDLTNSSQRFIQRHDSLSSVPSSSSSRKNSQGSNRSLDTITLSGDERDFGRLNVKLFYNSSVEQIWITVLQCRDLSWPSSYGDTPTVSIKGILTLPKPVHFKSSAKEGSNAIEFMETFVFAIKLQNLQTVRLVFKIQTQTPRKKTIGECSMSLRTLSTQEMDYSLDITPPSKISVCHAELELGTCFQAVNSRIQLQILEARYLPSSSTPLTLSFFVKVGMFSSGELIYKKKTRLLKASNGRVKWGETMIFPLIQSEKEIVFLIKLYSRSSVRRKHFVGQIWISEDSNNIEAVNQWKETVINPEKVVIRWHKLNPS

Target ORF information:

RefSeq Version	NM_001128596.3
Organism	Homo sapiens(human)
Definition	Homo sapiens tandem C2 domains, nuclear (TC2N), transcript variant 3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001128596.3

ORF Insert Sequence:

ATGGCAACAG AATTTATAAA GAGTTGCTGT GGAGGATGTT TCTATGGTGA AACAGAAAAA 
CACAACTTTT CTGTGGAAAG AGATTTTAAA GCAGCAGTCC CAAATAGTCA AAATGCTACT 
ATCTCTGTAC CTCCATTGAC TTCTGTTTCT GTAAAGCCTC AGCTTGGCTG TACTGAGGAT 
TATTTGCTTT CCAAATTACC ATCTGATGGC AAAGAAGTAC CATTTGTGGT GCCCAAGTTT 
AAGTTATCTT ACATTCAACC CAGGACACAA GAAACTCCTT CACATCTGGA AGAACTTGAA 
GGATCTGCCA GAGCATCTTT TGGAGATCGA AAGGTAGAAC TTTCCAGTTC ATCCCAGCAC 
GGACCTAGCT ATGATGTGTA TAACCCATTC TATATGTATC AGCACATTTC ACCTGATTTG 
AGTCGACGCT TTCCTCCCCG TTCAGAAGTG AAGAGACTGT ATGGATCGGT TTGTGATTTA 
AGGACGAACA AACTTCCCGG TTCCCCTGGG CTAAGCAAAT CTATGTTTGA TCTTACAAAC 
TCATCTCAGC GATTCATCCA GAGACATGAT TCATTGTCCA GTGTACCCAG TAGTTCTTCT 
TCAAGGAAAA ATTCTCAGGG GAGTAACAGA AGCCTGGATA CAATTACTCT ATCAGGAGAT 
GAAAGGGACT TTGGGAGACT GAATGTGAAA TTGTTTTATA ATTCTTCAGT AGAACAGATC 
TGGATCACAG TTTTACAGTG CAGAGATTTA AGTTGGCCCT CTAGTTATGG AGACACTCCT 
ACTGTTTCTA TAAAAGGAAT ACTTACATTG CCCAAACCAG TGCATTTCAA ATCTTCAGCC 
AAGGAAGGTT CCAACGCTAT TGAATTTATG GAAACGTTTG TATTTGCTAT TAAACTTCAA 
AATCTACAAA CTGTAAGACT TGTATTTAAG ATTCAAACCC AGACTCCCAG GAAGAAAACC 
ATTGGAGAAT GCTCAATGTC ACTCAGAACC CTTAGCACAC AGGAAATGGA TTACTCTTTG 
GATATAACAC CACCTTCAAA AATTTCTGTT TGCCATGCAG AACTTGAATT GGGGACTTGT 
TTTCAAGCAG TAAATAGCAG AATTCAGTTA CAAATTCTTG AGGCACGGTA CCTTCCAAGC 
TCATCAACAC CTCTGACTTT GAGTTTTTTC GTGAAGGTGG GAATGTTTAG CTCGGGAGAG 
TTGATTTATA AGAAAAAGAC ACGCTTACTG AAGGCCTCCA ATGGAAGAGT CAAGTGGGGA 
GAGACTATGA TTTTTCCACT TATACAGAGT GAAAAAGAAA TTGTTTTTCT CATTAAGCTT 
TACAGTCGAA GCTCTGTAAG AAGAAAACAC TTTGTGGGCC AGATTTGGAT AAGTGAAGAC 
AGTAATAACA TTGAAGCAGT GAACCAGTGG AAAGAGACAG TAATAAATCC AGAAAAGGTT 
GTTATCAGGT GGCACAAATT AAATCCATCT TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

TC2N ( NM_001128595.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_001122067.2 Homo sapiens tandem C2 domains, nuclear (TC2N), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu107592
Clone ID Related Accession (Same CDS sequence)	NM_001128596.3 , NM_001128595.3 , NM_152332.6
Accession Version	NM_001128595.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1473bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-08-07
Organism	Homo sapiens(human)
Product	tandem C2 domains nuclear protein isoform 1
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AL121839.3. On Jun 1, 2019 this sequence version replaced NM_001128595.2. Transcript Variant: This variant (2) uses an alternate splice site in the 5' UTR, compared to variant 1. Variants 1, 2, and 3 encode the same isoform (1). Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. ##Evidence-Data-START## Transcript exon combination :: BX647828.1, SRR7346977.1527470.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGCAACAG AATTTATAAA GAGTTGCTGT GGAGGATGTT TCTATGGTGA AACAGAAAAA 
CACAACTTTT CTGTGGAAAG AGATTTTAAA GCAGCAGTCC CAAATAGTCA AAATGCTACT 
ATCTCTGTAC CTCCATTGAC TTCTGTTTCT GTAAAGCCTC AGCTTGGCTG TACTGAGGAT 
TATTTGCTTT CCAAATTACC ATCTGATGGC AAAGAAGTAC CATTTGTGGT GCCCAAGTTT 
AAGTTATCTT ACATTCAACC CAGGACACAA GAAACTCCTT CACATCTGGA AGAACTTGAA 
GGATCTGCCA GAGCATCTTT TGGAGATCGA AAGGTAGAAC TTTCCAGTTC ATCCCAGCAC 
GGACCTAGCT ATGATGTGTA TAACCCATTC TATATGTATC AGCACATTTC ACCTGATTTG 
AGTCGACGCT TTCCTCCCCG TTCAGAAGTG AAGAGACTGT ATGGATCGGT TTGTGATTTA 
AGGACGAACA AACTTCCCGG TTCCCCTGGG CTAAGCAAAT CTATGTTTGA TCTTACAAAC 
TCATCTCAGC GATTCATCCA GAGACATGAT TCATTGTCCA GTGTACCCAG TAGTTCTTCT 
TCAAGGAAAA ATTCTCAGGG GAGTAACAGA AGCCTGGATA CAATTACTCT ATCAGGAGAT 
GAAAGGGACT TTGGGAGACT GAATGTGAAA TTGTTTTATA ATTCTTCAGT AGAACAGATC 
TGGATCACAG TTTTACAGTG CAGAGATTTA AGTTGGCCCT CTAGTTATGG AGACACTCCT 
ACTGTTTCTA TAAAAGGAAT ACTTACATTG CCCAAACCAG TGCATTTCAA ATCTTCAGCC 
AAGGAAGGTT CCAACGCTAT TGAATTTATG GAAACGTTTG TATTTGCTAT TAAACTTCAA 
AATCTACAAA CTGTAAGACT TGTATTTAAG ATTCAAACCC AGACTCCCAG GAAGAAAACC 
ATTGGAGAAT GCTCAATGTC ACTCAGAACC CTTAGCACAC AGGAAATGGA TTACTCTTTG 
GATATAACAC CACCTTCAAA AATTTCTGTT TGCCATGCAG AACTTGAATT GGGGACTTGT 
TTTCAAGCAG TAAATAGCAG AATTCAGTTA CAAATTCTTG AGGCACGGTA CCTTCCAAGC 
TCATCAACAC CTCTGACTTT GAGTTTTTTC GTGAAGGTGG GAATGTTTAG CTCGGGAGAG 
TTGATTTATA AGAAAAAGAC ACGCTTACTG AAGGCCTCCA ATGGAAGAGT CAAGTGGGGA 
GAGACTATGA TTTTTCCACT TATACAGAGT GAAAAAGAAA TTGTTTTTCT CATTAAGCTT 
TACAGTCGAA GCTCTGTAAG AAGAAAACAC TTTGTGGGCC AGATTTGGAT AAGTGAAGAC 
AGTAATAACA TTGAAGCAGT GAACCAGTGG AAAGAGACAG TAATAAATCC AGAAAAGGTT 
GTTATCAGGT GGCACAAATT AAATCCATCT TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001122067.2
CDS	142..1614
Translation	MATEFIKSCCGGCFYGETEKHNFSVERDFKAAVPNSQNATISVPPLTSVSVKPQLGCTEDYLLSKLPSDGKEVPFVVPKFKLSYIQPRTQETPSHLEELEGSARASFGDRKVELSSSSQHGPSYDVYNPFYMYQHISPDLSRRFPPRSEVKRLYGSVCDLRTNKLPGSPGLSKSMFDLTNSSQRFIQRHDSLSSVPSSSSSRKNSQGSNRSLDTITLSGDERDFGRLNVKLFYNSSVEQIWITVLQCRDLSWPSSYGDTPTVSIKGILTLPKPVHFKSSAKEGSNAIEFMETFVFAIKLQNLQTVRLVFKIQTQTPRKKTIGECSMSLRTLSTQEMDYSLDITPPSKISVCHAELELGTCFQAVNSRIQLQILEARYLPSSSTPLTLSFFVKVGMFSSGELIYKKKTRLLKASNGRVKWGETMIFPLIQSEKEIVFLIKLYSRSSVRRKHFVGQIWISEDSNNIEAVNQWKETVINPEKVVIRWHKLNPS

Target ORF information:

RefSeq Version	NM_001128595.3
Organism	Homo sapiens(human)
Definition	Homo sapiens tandem C2 domains, nuclear (TC2N), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001128595.3

ORF Insert Sequence:

ATGGCAACAG AATTTATAAA GAGTTGCTGT GGAGGATGTT TCTATGGTGA AACAGAAAAA 
CACAACTTTT CTGTGGAAAG AGATTTTAAA GCAGCAGTCC CAAATAGTCA AAATGCTACT 
ATCTCTGTAC CTCCATTGAC TTCTGTTTCT GTAAAGCCTC AGCTTGGCTG TACTGAGGAT 
TATTTGCTTT CCAAATTACC ATCTGATGGC AAAGAAGTAC CATTTGTGGT GCCCAAGTTT 
AAGTTATCTT ACATTCAACC CAGGACACAA GAAACTCCTT CACATCTGGA AGAACTTGAA 
GGATCTGCCA GAGCATCTTT TGGAGATCGA AAGGTAGAAC TTTCCAGTTC ATCCCAGCAC 
GGACCTAGCT ATGATGTGTA TAACCCATTC TATATGTATC AGCACATTTC ACCTGATTTG 
AGTCGACGCT TTCCTCCCCG TTCAGAAGTG AAGAGACTGT ATGGATCGGT TTGTGATTTA 
AGGACGAACA AACTTCCCGG TTCCCCTGGG CTAAGCAAAT CTATGTTTGA TCTTACAAAC 
TCATCTCAGC GATTCATCCA GAGACATGAT TCATTGTCCA GTGTACCCAG TAGTTCTTCT 
TCAAGGAAAA ATTCTCAGGG GAGTAACAGA AGCCTGGATA CAATTACTCT ATCAGGAGAT 
GAAAGGGACT TTGGGAGACT GAATGTGAAA TTGTTTTATA ATTCTTCAGT AGAACAGATC 
TGGATCACAG TTTTACAGTG CAGAGATTTA AGTTGGCCCT CTAGTTATGG AGACACTCCT 
ACTGTTTCTA TAAAAGGAAT ACTTACATTG CCCAAACCAG TGCATTTCAA ATCTTCAGCC 
AAGGAAGGTT CCAACGCTAT TGAATTTATG GAAACGTTTG TATTTGCTAT TAAACTTCAA 
AATCTACAAA CTGTAAGACT TGTATTTAAG ATTCAAACCC AGACTCCCAG GAAGAAAACC 
ATTGGAGAAT GCTCAATGTC ACTCAGAACC CTTAGCACAC AGGAAATGGA TTACTCTTTG 
GATATAACAC CACCTTCAAA AATTTCTGTT TGCCATGCAG AACTTGAATT GGGGACTTGT 
TTTCAAGCAG TAAATAGCAG AATTCAGTTA CAAATTCTTG AGGCACGGTA CCTTCCAAGC 
TCATCAACAC CTCTGACTTT GAGTTTTTTC GTGAAGGTGG GAATGTTTAG CTCGGGAGAG 
TTGATTTATA AGAAAAAGAC ACGCTTACTG AAGGCCTCCA ATGGAAGAGT CAAGTGGGGA 
GAGACTATGA TTTTTCCACT TATACAGAGT GAAAAAGAAA TTGTTTTTCT CATTAAGCTT 
TACAGTCGAA GCTCTGTAAG AAGAAAACAC TTTGTGGGCC AGATTTGGAT AAGTGAAGAC 
AGTAATAACA TTGAAGCAGT GAACCAGTGG AAAGAGACAG TAATAAATCC AGAAAAGGTT 
GTTATCAGGT GGCACAAATT AAATCCATCT TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

TC2N ( NM_152332.6 ) cDNA ORF clone, Homo sapiens(human) -> NP_689545.2 Homo sapiens tandem C2 domains, nuclear (TC2N), transcript variant 1, mRNA.

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CloneID	OHu107592
Clone ID Related Accession (Same CDS sequence)	NM_001128596.3 , NM_001128595.3 , NM_152332.6
Accession Version	NM_152332.6 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1473bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-08-07
Organism	Homo sapiens(human)
Product	tandem C2 domains nuclear protein isoform 1
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AL121839.3. On May 31, 2019 this sequence version replaced NM_152332.5. Transcript Variant: This variant (1) represents the longest transcript and encodes the longer isoform (1). Variants 1, 2, and 3 encode the same isoform (1). Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. ##Evidence-Data-START## Transcript exon combination :: BC040503.1, SRR7346977.1503511.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGCAACAG AATTTATAAA GAGTTGCTGT GGAGGATGTT TCTATGGTGA AACAGAAAAA 
CACAACTTTT CTGTGGAAAG AGATTTTAAA GCAGCAGTCC CAAATAGTCA AAATGCTACT 
ATCTCTGTAC CTCCATTGAC TTCTGTTTCT GTAAAGCCTC AGCTTGGCTG TACTGAGGAT 
TATTTGCTTT CCAAATTACC ATCTGATGGC AAAGAAGTAC CATTTGTGGT GCCCAAGTTT 
AAGTTATCTT ACATTCAACC CAGGACACAA GAAACTCCTT CACATCTGGA AGAACTTGAA 
GGATCTGCCA GAGCATCTTT TGGAGATCGA AAGGTAGAAC TTTCCAGTTC ATCCCAGCAC 
GGACCTAGCT ATGATGTGTA TAACCCATTC TATATGTATC AGCACATTTC ACCTGATTTG 
AGTCGACGCT TTCCTCCCCG TTCAGAAGTG AAGAGACTGT ATGGATCGGT TTGTGATTTA 
AGGACGAACA AACTTCCCGG TTCCCCTGGG CTAAGCAAAT CTATGTTTGA TCTTACAAAC 
TCATCTCAGC GATTCATCCA GAGACATGAT TCATTGTCCA GTGTACCCAG TAGTTCTTCT 
TCAAGGAAAA ATTCTCAGGG GAGTAACAGA AGCCTGGATA CAATTACTCT ATCAGGAGAT 
GAAAGGGACT TTGGGAGACT GAATGTGAAA TTGTTTTATA ATTCTTCAGT AGAACAGATC 
TGGATCACAG TTTTACAGTG CAGAGATTTA AGTTGGCCCT CTAGTTATGG AGACACTCCT 
ACTGTTTCTA TAAAAGGAAT ACTTACATTG CCCAAACCAG TGCATTTCAA ATCTTCAGCC 
AAGGAAGGTT CCAACGCTAT TGAATTTATG GAAACGTTTG TATTTGCTAT TAAACTTCAA 
AATCTACAAA CTGTAAGACT TGTATTTAAG ATTCAAACCC AGACTCCCAG GAAGAAAACC 
ATTGGAGAAT GCTCAATGTC ACTCAGAACC CTTAGCACAC AGGAAATGGA TTACTCTTTG 
GATATAACAC CACCTTCAAA AATTTCTGTT TGCCATGCAG AACTTGAATT GGGGACTTGT 
TTTCAAGCAG TAAATAGCAG AATTCAGTTA CAAATTCTTG AGGCACGGTA CCTTCCAAGC 
TCATCAACAC CTCTGACTTT GAGTTTTTTC GTGAAGGTGG GAATGTTTAG CTCGGGAGAG 
TTGATTTATA AGAAAAAGAC ACGCTTACTG AAGGCCTCCA ATGGAAGAGT CAAGTGGGGA 
GAGACTATGA TTTTTCCACT TATACAGAGT GAAAAAGAAA TTGTTTTTCT CATTAAGCTT 
TACAGTCGAA GCTCTGTAAG AAGAAAACAC TTTGTGGGCC AGATTTGGAT AAGTGAAGAC 
AGTAATAACA TTGAAGCAGT GAACCAGTGG AAAGAGACAG TAATAAATCC AGAAAAGGTT 
GTTATCAGGT GGCACAAATT AAATCCATCT TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_689545.2
CDS	330..1802
Translation	MATEFIKSCCGGCFYGETEKHNFSVERDFKAAVPNSQNATISVPPLTSVSVKPQLGCTEDYLLSKLPSDGKEVPFVVPKFKLSYIQPRTQETPSHLEELEGSARASFGDRKVELSSSSQHGPSYDVYNPFYMYQHISPDLSRRFPPRSEVKRLYGSVCDLRTNKLPGSPGLSKSMFDLTNSSQRFIQRHDSLSSVPSSSSSRKNSQGSNRSLDTITLSGDERDFGRLNVKLFYNSSVEQIWITVLQCRDLSWPSSYGDTPTVSIKGILTLPKPVHFKSSAKEGSNAIEFMETFVFAIKLQNLQTVRLVFKIQTQTPRKKTIGECSMSLRTLSTQEMDYSLDITPPSKISVCHAELELGTCFQAVNSRIQLQILEARYLPSSSTPLTLSFFVKVGMFSSGELIYKKKTRLLKASNGRVKWGETMIFPLIQSEKEIVFLIKLYSRSSVRRKHFVGQIWISEDSNNIEAVNQWKETVINPEKVVIRWHKLNPS

Target ORF information:

RefSeq Version	NM_152332.6
Organism	Homo sapiens(human)
Definition	Homo sapiens tandem C2 domains, nuclear (TC2N), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_152332.6

ORF Insert Sequence:

ATGGCAACAG AATTTATAAA GAGTTGCTGT GGAGGATGTT TCTATGGTGA AACAGAAAAA 
CACAACTTTT CTGTGGAAAG AGATTTTAAA GCAGCAGTCC CAAATAGTCA AAATGCTACT 
ATCTCTGTAC CTCCATTGAC TTCTGTTTCT GTAAAGCCTC AGCTTGGCTG TACTGAGGAT 
TATTTGCTTT CCAAATTACC ATCTGATGGC AAAGAAGTAC CATTTGTGGT GCCCAAGTTT 
AAGTTATCTT ACATTCAACC CAGGACACAA GAAACTCCTT CACATCTGGA AGAACTTGAA 
GGATCTGCCA GAGCATCTTT TGGAGATCGA AAGGTAGAAC TTTCCAGTTC ATCCCAGCAC 
GGACCTAGCT ATGATGTGTA TAACCCATTC TATATGTATC AGCACATTTC ACCTGATTTG 
AGTCGACGCT TTCCTCCCCG TTCAGAAGTG AAGAGACTGT ATGGATCGGT TTGTGATTTA 
AGGACGAACA AACTTCCCGG TTCCCCTGGG CTAAGCAAAT CTATGTTTGA TCTTACAAAC 
TCATCTCAGC GATTCATCCA GAGACATGAT TCATTGTCCA GTGTACCCAG TAGTTCTTCT 
TCAAGGAAAA ATTCTCAGGG GAGTAACAGA AGCCTGGATA CAATTACTCT ATCAGGAGAT 
GAAAGGGACT TTGGGAGACT GAATGTGAAA TTGTTTTATA ATTCTTCAGT AGAACAGATC 
TGGATCACAG TTTTACAGTG CAGAGATTTA AGTTGGCCCT CTAGTTATGG AGACACTCCT 
ACTGTTTCTA TAAAAGGAAT ACTTACATTG CCCAAACCAG TGCATTTCAA ATCTTCAGCC 
AAGGAAGGTT CCAACGCTAT TGAATTTATG GAAACGTTTG TATTTGCTAT TAAACTTCAA 
AATCTACAAA CTGTAAGACT TGTATTTAAG ATTCAAACCC AGACTCCCAG GAAGAAAACC 
ATTGGAGAAT GCTCAATGTC ACTCAGAACC CTTAGCACAC AGGAAATGGA TTACTCTTTG 
GATATAACAC CACCTTCAAA AATTTCTGTT TGCCATGCAG AACTTGAATT GGGGACTTGT 
TTTCAAGCAG TAAATAGCAG AATTCAGTTA CAAATTCTTG AGGCACGGTA CCTTCCAAGC 
TCATCAACAC CTCTGACTTT GAGTTTTTTC GTGAAGGTGG GAATGTTTAG CTCGGGAGAG 
TTGATTTATA AGAAAAAGAC ACGCTTACTG AAGGCCTCCA ATGGAAGAGT CAAGTGGGGA 
GAGACTATGA TTTTTCCACT TATACAGAGT GAAAAAGAAA TTGTTTTTCT CATTAAGCTT 
TACAGTCGAA GCTCTGTAAG AAGAAAACAC TTTGTGGGCC AGATTTGGAT AAGTGAAGAC 
AGTAATAACA TTGAAGCAGT GAACCAGTGG AAAGAGACAG TAATAAATCC AGAAAAGGTT 
GTTATCAGGT GGCACAAATT AAATCCATCT TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

TC2N ( NM_001289134.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_001276063.2 Homo sapiens tandem C2 domains, nuclear (TC2N), transcript variant 4, mRNA.

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CloneID	OHu108225
Clone ID Related Accession (Same CDS sequence)	NM_001289134.2
Accession Version	NM_001289134.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1281bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-08-06
Organism	Homo sapiens(human)
Product	tandem C2 domains nuclear protein isoform 2
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AL121839.3. On May 31, 2019 this sequence version replaced NM_001289134.1. Transcript Variant: This variant (4) uses an alternate splice site in the 5' UTR and lacks an alternate in-frame exon, compared to variant 1. The encoded isoform (2) is shorter than isoform 1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. ##Evidence-Data-START## Transcript exon combination :: AK126359.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGCAACAG AATTTATAAA GAGTTGCTGT GGAGGATGTT TCTATGGTGA AACAGAAAAA 
CACAACTTTT CTGTGGAAAG AGATTTTAAA GCAGCAGTCC CAAATAGTCA AAATGCTACT 
ATCTCTGTAC CTCCATTGAC TTCTGTTTCT GTAAAGCCTC AGCTTGGCTG TACTGAGGAT 
TATTTGCTTT CCAAATTACC ATCTGATGGC AAAGAAGTAC CATTTGTGGT GCCCAAGTTT 
AAGTTATCTT ACATTCAACC CAGGACACAA GAAACTCCTT CACATCTGGA AGAACTTGAA 
GGATCTGCCA GAGCATCTTT TGGAGATCGA AAGGTAGAAC TTTCCAGTTC ATCCCAGCAC 
GGACCTAGCT ATGATGTGTA TAACCCATTC TATATGTATC AGCACATTTC ACCTGATTTG 
AGTCGACGCT TTCCTCCCCG TTCAGAAGTG AAGAGACTGT ATGGATCGGT TTGTGATTTA 
AGGACGAACA AACTTCCCGG TTCCCCTGGG CTAAGCAAAT CTATGTTTGA TCTTACAAAC 
TCATCTCAGC GATTCATCCA GAGACATGAT TCATTGTCCA GTGTACCCAG TAGTTCTTCT 
TCAAGGAAAA ATTCTCAGGG GAGTAACAGA AGCCTGGATA CAATTACTCT ATCAGGAGAT 
GAAAGGGACT TTGGGAGACT GAATGTGAAA TTGTTTTATA ATTCTTCAGT AGAACAGATC 
TGGATCACAG TTTTACAGTG CAGAGATTTA AGTTGGCCCT CTAGTTATGG AGACACTCCT 
ACTGTTTCTA TAAAAGGAAT ACTTACATTG CCCAAACCAG TGCATTTCAA ATCTTCAGCC 
AAGGAAGGTT CCAACGTTTG CCATGCAGAA CTTGAATTGG GGACTTGTTT TCAAGCAGTA 
AATAGCAGAA TTCAGTTACA AATTCTTGAG GCACGGTACC TTCCAAGCTC ATCAACACCT 
CTGACTTTGA GTTTTTTCGT GAAGGTGGGA ATGTTTAGCT CGGGAGAGTT GATTTATAAG 
AAAAAGACAC GCTTACTGAA GGCCTCCAAT GGAAGAGTCA AGTGGGGAGA GACTATGATT 
TTTCCACTTA TACAGAGTGA AAAAGAAATT GTTTTTCTCA TTAAGCTTTA CAGTCGAAGC 
TCTGTAAGAA GAAAACACTT TGTGGGCCAG ATTTGGATAA GTGAAGACAG TAATAACATT 
GAAGCAGTGA ACCAGTGGAA AGAGACAGTA ATAAATCCAG AAAAGGTTGT TATCAGGTGG 
CACAAATTAA ATCCATCTTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001276063.2
CDS	142..1422
Translation	MATEFIKSCCGGCFYGETEKHNFSVERDFKAAVPNSQNATISVPPLTSVSVKPQLGCTEDYLLSKLPSDGKEVPFVVPKFKLSYIQPRTQETPSHLEELEGSARASFGDRKVELSSSSQHGPSYDVYNPFYMYQHISPDLSRRFPPRSEVKRLYGSVCDLRTNKLPGSPGLSKSMFDLTNSSQRFIQRHDSLSSVPSSSSSRKNSQGSNRSLDTITLSGDERDFGRLNVKLFYNSSVEQIWITVLQCRDLSWPSSYGDTPTVSIKGILTLPKPVHFKSSAKEGSNVCHAELELGTCFQAVNSRIQLQILEARYLPSSSTPLTLSFFVKVGMFSSGELIYKKKTRLLKASNGRVKWGETMIFPLIQSEKEIVFLIKLYSRSSVRRKHFVGQIWISEDSNNIEAVNQWKETVINPEKVVIRWHKLNPS

Target ORF information:

RefSeq Version	NM_001289134.2
Organism	Homo sapiens(human)
Definition	Homo sapiens tandem C2 domains, nuclear (TC2N), transcript variant 4, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001289134.2

ORF Insert Sequence:

ATGGCAACAG AATTTATAAA GAGTTGCTGT GGAGGATGTT TCTATGGTGA AACAGAAAAA 
CACAACTTTT CTGTGGAAAG AGATTTTAAA GCAGCAGTCC CAAATAGTCA AAATGCTACT 
ATCTCTGTAC CTCCATTGAC TTCTGTTTCT GTAAAGCCTC AGCTTGGCTG TACTGAGGAT 
TATTTGCTTT CCAAATTACC ATCTGATGGC AAAGAAGTAC CATTTGTGGT GCCCAAGTTT 
AAGTTATCTT ACATTCAACC CAGGACACAA GAAACTCCTT CACATCTGGA AGAACTTGAA 
GGATCTGCCA GAGCATCTTT TGGAGATCGA AAGGTAGAAC TTTCCAGTTC ATCCCAGCAC 
GGACCTAGCT ATGATGTGTA TAACCCATTC TATATGTATC AGCACATTTC ACCTGATTTG 
AGTCGACGCT TTCCTCCCCG TTCAGAAGTG AAGAGACTGT ATGGATCGGT TTGTGATTTA 
AGGACGAACA AACTTCCCGG TTCCCCTGGG CTAAGCAAAT CTATGTTTGA TCTTACAAAC 
TCATCTCAGC GATTCATCCA GAGACATGAT TCATTGTCCA GTGTACCCAG TAGTTCTTCT 
TCAAGGAAAA ATTCTCAGGG GAGTAACAGA AGCCTGGATA CAATTACTCT ATCAGGAGAT 
GAAAGGGACT TTGGGAGACT GAATGTGAAA TTGTTTTATA ATTCTTCAGT AGAACAGATC 
TGGATCACAG TTTTACAGTG CAGAGATTTA AGTTGGCCCT CTAGTTATGG AGACACTCCT 
ACTGTTTCTA TAAAAGGAAT ACTTACATTG CCCAAACCAG TGCATTTCAA ATCTTCAGCC 
AAGGAAGGTT CCAACGTTTG CCATGCAGAA CTTGAATTGG GGACTTGTTT TCAAGCAGTA 
AATAGCAGAA TTCAGTTACA AATTCTTGAG GCACGGTACC TTCCAAGCTC ATCAACACCT 
CTGACTTTGA GTTTTTTCGT GAAGGTGGGA ATGTTTAGCT CGGGAGAGTT GATTTATAAG 
AAAAAGACAC GCTTACTGAA GGCCTCCAAT GGAAGAGTCA AGTGGGGAGA GACTATGATT 
TTTCCACTTA TACAGAGTGA AAAAGAAATT GTTTTTCTCA TTAAGCTTTA CAGTCGAAGC 
TCTGTAAGAA GAAAACACTT TGTGGGCCAG ATTTGGATAA GTGAAGACAG TAATAACATT 
GAAGCAGTGA ACCAGTGGAA AGAGACAGTA ATAAATCCAG AAAAGGTTGT TATCAGGTGG 
CACAAATTAA ATCCATCTTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Combined analysis of three genome-wide association studies on vWF and FVIII plasma levels.
BMC medical genetics12102(2011 Aug)
Antoni G,Oudot-Mellakh T,Dimitromanolakis A,Germain M,Cohen W,Wells P,Lathrop M,Gagnon F,Morange PE,Tregouet DA

Impact on venous thrombosis risk of newly discovered gene variants associated with FVIII and VWF plasma levels.
Journal of thrombosis and haemostasis : JTH9(1)229-31(2011 Jan)
Morange PE,Saut N,Antoni G,Emmerich J,Tr?gou?t DA

Tac2-N, an atypical C-type tandem C2 protein localized in the nucleus.
FEBS letters503(2-3)217-8(2001 Aug)
Fukuda M,Mikoshiba K

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TC2N cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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