LRIG3 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	LRIG3
Entrez Gene ID	121227
Full Name	leucine rich repeats and immunoglobulin like domains 3
Synonyms	LIG3
General protein information	Preferred Names leucine rich repeats and immunoglobulin like domains 3 Names leucine-rich repeats and immunoglobulin-like domains protein 3 LIG-3
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 12 Map Location: 12q14.1
Disorder MIM:	608870

mRNA and Protein(s)

mRNA	Protein	Name
XM_017018790.1	XP_016874279.1	leucine-rich repeats and immunoglobulin-like domains protein 3 isoform X2
NM_153377.4	NP_700356.2	leucine-rich repeats and immunoglobulin-like domains protein 3 isoform 2 precursor
NM_001136051.2	NP_001129523.1	leucine-rich repeats and immunoglobulin-like domains protein 3 isoform 1 precursor
XM_017018790.2	XP_016874279.1	leucine-rich repeats and immunoglobulin-like domains protein 3 isoform X1
XM_011537893.2	XP_011536195.1	leucine-rich repeats and immunoglobulin-like domains protein 3 isoform X1

Pathways from BioSystems

Homologies

Canis lupus familiaris (dog)	LRIG3	XP_005625618.1
Gallus gallus (chicken)	LRIG3	NP_001186484.1
Drosophila melanogaster (fruit fly)	lbk	NP_611091.2
Xenopus tropicalis (tropical clawed frog)	lrig3	XP_002940426.2
Pan troglodytes (chimpanzee)	LRIG3	XP_001167069.1
Mus musculus (house mouse)	Lrig3	NP_796126.4
Rattus norvegicus (Norway rat)	Lrig3	XP_216905.5
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP009688	XP_318747.4
Caenorhabditis elegans (roundworm)	sma-10	NP_499896.1
Bos taurus (cattle)	LRIG3	NP_001192520.1
Danio rerio (zebrafish)	lrig3	NP_001103817.1
Homo sapiens (human)	LRIG3	NP_700356.2
	LRIG3	XP_001116602.1

Gene Ontology
Bibliography

Related articles in PubMed

LRIGs: A Prognostically Significant Family with Emerging Therapeutic Competence against Cancers.
Malik U, Javed A
Current cancer drug targets17(1)3-16(2017)

Variants in the genes DCTN2, DNAH10, LRIG3, and MYO1A are associated with intermediate Charcot-Marie-Tooth disease in a Norwegian family.
Braathen GJ, H?yer H, Busk ?L, Tveten K, Skjelbred CF, Russell MB
Acta neurologica Scandinavica134(1)67-75(2016 Jul)

LRIG3 modulates proliferation, apoptosis and invasion of glioblastoma cells as a potent tumor suppressor.
Guo D, Yang H, Guo Y, Xiao Q, Mao F, Tan Y, Wan X, Wang B, Lei T
Journal of the neurological sciences350(1-2)61-8(2015 Mar)

Expression and significance of LRIG3 in human cervical squamous cell carcinoma.
Guo L, Zhang W, Sheng Y, Chen K, Shi Q, Zhang P, Zhang R
European journal of gynaecological oncology36(4)414-9(2015)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Role of LRIG3 in cancer [review]
Title: LRIGs: A Prognostically Significant Family with Emerging Therapeutic Competence against Cancers.

This is the first time a haplotype on chromosome 12 containing sequence variants in the genes DCTN2, DNAH10, LRIG3, and MYO1A has been linked to an inherited neuropathy in humans.
Title: Variants in the genes DCTN2, DNAH10, LRIG3, and MYO1A are associated with intermediate Charcot-Marie-Tooth disease in a Norwegian family.

LRIG3 functions as a tumor suppressor by attenuating EGFR signaling pathway.
Title: LRIG3 modulates proliferation, apoptosis and invasion of glioblastoma cells as a potent tumor suppressor.

LRIG3 plays an important role in Hela229 cell proliferation, apoptosis, and invasiveness.
Title: Expression and significance of LRIG3 in human cervical squamous cell carcinoma.

The results on expression of other tumor markers suggest that LRIG3 is influenced by or influences a pattern of tumor markers in cancer and precancerous cells.
Title: Immunohistochemical LRIG3 expression in cervical intraepithelial neoplasia and invasive squamous cell cervical cancer: association with expression of tumor markers, hormones, high-risk HPV-infection, smoking and patient outcome.

The following LRIG3 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the LRIG3 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu83514	XM_017018790.2 Latest version!	Homo sapiens leucine rich repeats and immunoglobulin like domains 3 (LRIG3), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	14-16	$307.30 $439.00
OHu07008	NM_153377.4 Latest version!	Homo sapiens leucine rich repeats and immunoglobulin like domains 3 (LRIG3), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	20	$384.30 $549.00
OHu07391	NM_001136051.2 Latest version!	Homo sapiens leucine rich repeats and immunoglobulin like domains 3 (LRIG3), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	20	$559.30 $799.00
OHu75145	XM_011537893.2 Latest version!	Homo sapiens leucine-rich repeats and immunoglobulin like domains 3 (LRIG3), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	20	$559.30 $799.00
View Old Accession Versions >>
OHu83514	XM_017018790.1	Homo sapiens leucine-rich repeats and immunoglobulin like domains 3 (LRIG3), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	14-16	$307.30 $439.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

LRIG3 ( XM_017018790.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_016874279.1 Homo sapiens leucine-rich repeats and immunoglobulin like domains 3 (LRIG3), transcript variant X2, mRNA.

Price & Availability↑

CloneID	OHu83514
Clone ID Related Accession (Same CDS sequence)	XM_017018790.1 , XM_017018790.2
Accession Version	XM_017018790.1	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1872bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-06-05
Organism	Homo sapiens(human)
Product	leucine-rich repeats and immunoglobulin-like domains protein 3 isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000012.12) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGAGCGCGC CGAGCCTCCG TGCGCGCGCC GCGGGGTTGG GGCTGCTGCT GTGCGCGGTG 
CTGGGGCGCG CTGGCCGGTC AGACAGCGGC GGTCGCGGGG AACTCGGGCA GCCCTCTGGG 
GTAGCCGCCG AGCGCCCATG CCCCACTACC TGCCGCTGCC TCGGGGACCT GCTGGACTGC 
AGTCGTAAGC GGCTAGCGCG TCTTCCCGAG CCACTCCCGT CCTGGGTCGC TCGGCTGGAC 
TTAAGTCACA ACAGATTATC TTTCATCAAG GCAAGTTCCA TGAGCCACCT TCAAAGCCTT 
CGAGAAGTGA AACTGAACAA CAATGAATTG GAGACCATTC CAAATCTGGG ACCAGTCTCG 
GCAAATATTA CACTTCTCTC CTTGGCTGGA AACAGGATTG TTGAAATACT CCCTGAACAT 
CTGAAAGAGT TTCAGTCCCT TGAAACTTTG GACCTTAGCA GCAACAATAT TTCAGAGCTC 
CAAACTGCAT TTCCAGCCCT ACAGCTCAAA TATCTGTATC TCAACAGCAA CCGAGTCACA 
TCAATGGAAC CTGGGTATTT TGACAATTTG GCCAACACAC TCCTTGTGTT AAAGCTGAAC 
AGGAACCGAA TCTCAGCTAT CCCACCCAAG ATGTTTAAAC TGCCCCAACT GCAACATCTC 
GAATTGAACC GAAACAAGAT TAAAAATGTA GATGGACTGA CATTCCAAGG CCTTGGTGCT 
CTGAAGTCTC TGAAAATGCA AAGAAATGGA GTAACGAAAC TTATGGATGG AGCTTTTTGG 
GGGCTGAGCA ACATGGAAAT TTTGCAGCTG GACCATAACA ACCTAACAGA GATTACCAAA 
GGCTGGCTTT ACGGCTTGCT GATGCTGCAG GAACTTCATC TCAGCCAAAA TGCCATCAAC 
AGGATCAGCC CTGATGCCTG GGAGTTCTGC CAGAAGCTCA GTGAGCTGGA CCTAACTTTC 
AATCACTTAT CAAGGTTAGA TGATTCAAGC TTCCTTGGCC TAAGCTTACT AAATACACTG 
CACATTGGGA ACAACAGAGT CAGCTACATT GCTGATTGTG CCTTCCGGGG GCTTTCCAGT 
TTAAAGACTT TGGATCTGAA GAACAATGAA ATTTCCTGGA CTATTGAAGA CATGAATGGT 
GCTTTCTCTG GGCTTGACAA ACTGAGGCGA CTGATACTCC AAGGAAATCG GATCCGTTCT 
ATTACTAAAA AAGCCTTCAC TGGTTTGGAT GCATTGGAGC ATCTAGACCT GAGTGACAAC 
GCAATCATGT CTTTACAAGG CAATGCATTT TCACAAATGA AGAAACTGCA ACAATTGCAT 
TTAAATACAT CAAGCCTTTT GTGCGATTGC CAGCTAAAAT GGCTCCCACA GTGGGTGGCG 
GAAAACAACT TTCAGAGCTT TGTAAATGCC AGTTGTGCCC ATCCTCAGCT GCTAAAAGGA 
AGAAGCATTT TTGCTGTTAG CCCAGATGGC TTTGTGTGTG ATGATTTTCC CAAACCCCAG 
ATCACGGTTC AGCCAGAAAC ACAGTCGGCA ATAAAAGGTT CCAATTTGAG TTTCATCTGC 
TCAGCTGCCA GCAGCAGTGA TTCCCCAATG ACTTTTGCTT GGAAAAAAGA CAATGAACTA 
CTGCATGATG CTGAAATGGA AAATTATGCA CACCTCCGGG CCCAAGGTGG CGAGGTGATG 
GAGTATACCA CCATCCTTCG GCTGCGCGAG GTGGAATTTG CCAGTGAGGG GAAATATCAG 
TGTGTCATCT CCAATCACTT TGGTTCATCC TACTCTGTCA AAGCCAAGCT TACAGTAAAT 
ATTCCCCACC TGACTCTTCC TTTCCCTACC TTTCATTCCA CAAAATTAAG ATTCTTGGTT 
ATTTGTATCT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_016874279.1
CDS	306..2177
Translation	MSAPSLRARAAGLGLLLCAVLGRAGRSDSGGRGELGQPSGVAAERPCPTTCRCLGDLLDCSRKRLARLPEPLPSWVARLDLSHNRLSFIKASSMSHLQSLREVKLNNNELETIPNLGPVSANITLLSLAGNRIVEILPEHLKEFQSLETLDLSSNNISELQTAFPALQLKYLYLNSNRVTSMEPGYFDNLANTLLVLKLNRNRISAIPPKMFKLPQLQHLELNRNKIKNVDGLTFQGLGALKSLKMQRNGVTKLMDGAFWGLSNMEILQLDHNNLTEITKGWLYGLLMLQELHLSQNAINRISPDAWEFCQKLSELDLTFNHLSRLDDSSFLGLSLLNTLHIGNNRVSYIADCAFRGLSSLKTLDLKNNEISWTIEDMNGAFSGLDKLRRLILQGNRIRSITKKAFTGLDALEHLDLSDNAIMSLQGNAFSQMKKLQQLHLNTSSLLCDCQLKWLPQWVAENNFQSFVNASCAHPQLLKGRSIFAVSPDGFVCDDFPKPQITVQPETQSAIKGSNLSFICSAASSSDSPMTFAWKKDNELLHDAEMENYAHLRAQGGEVMEYTTILRLREVEFASEGKYQCVISNHFGSSYSVKAKLTVNIPHLTLPFPTFHSTKLRFLVICI

Target ORF information:

RefSeq Version	XM_017018790.1
Organism	Homo sapiens(human)
Definition	Homo sapiens leucine-rich repeats and immunoglobulin like domains 3 (LRIG3), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017018790.1

ORF Insert Sequence:

ATGAGCGCGC CGAGCCTCCG TGCGCGCGCC GCGGGGTTGG GGCTGCTGCT GTGCGCGGTG 
CTGGGGCGCG CTGGCCGGTC AGACAGCGGC GGTCGCGGGG AACTCGGGCA GCCCTCTGGG 
GTAGCCGCCG AGCGCCCATG CCCCACTACC TGCCGCTGCC TCGGGGACCT GCTGGACTGC 
AGTCGTAAGC GGCTAGCGCG TCTTCCCGAG CCACTCCCGT CCTGGGTCGC TCGGCTGGAC 
TTAAGTCACA ACAGATTATC TTTCATCAAG GCAAGTTCCA TGAGCCACCT TCAAAGCCTT 
CGAGAAGTGA AACTGAACAA CAATGAATTG GAGACCATTC CAAATCTGGG ACCAGTCTCG 
GCAAATATTA CACTTCTCTC CTTGGCTGGA AACAGGATTG TTGAAATACT CCCTGAACAT 
CTGAAAGAGT TTCAGTCCCT TGAAACTTTG GACCTTAGCA GCAACAATAT TTCAGAGCTC 
CAAACTGCAT TTCCAGCCCT ACAGCTCAAA TATCTGTATC TCAACAGCAA CCGAGTCACA 
TCAATGGAAC CTGGGTATTT TGACAATTTG GCCAACACAC TCCTTGTGTT AAAGCTGAAC 
AGGAACCGAA TCTCAGCTAT CCCACCCAAG ATGTTTAAAC TGCCCCAACT GCAACATCTC 
GAATTGAACC GAAACAAGAT TAAAAATGTA GATGGACTGA CATTCCAAGG CCTTGGTGCT 
CTGAAGTCTC TGAAAATGCA AAGAAATGGA GTAACGAAAC TTATGGATGG AGCTTTTTGG 
GGGCTGAGCA ACATGGAAAT TTTGCAGCTG GACCATAACA ACCTAACAGA GATTACCAAA 
GGCTGGCTTT ACGGCTTGCT GATGCTGCAG GAACTTCATC TCAGCCAAAA TGCCATCAAC 
AGGATCAGCC CTGATGCCTG GGAGTTCTGC CAGAAGCTCA GTGAGCTGGA CCTAACTTTC 
AATCACTTAT CAAGGTTAGA TGATTCAAGC TTCCTTGGCC TAAGCTTACT AAATACACTG 
CACATTGGGA ACAACAGAGT CAGCTACATT GCTGATTGTG CCTTCCGGGG GCTTTCCAGT 
TTAAAGACTT TGGATCTGAA GAACAATGAA ATTTCCTGGA CTATTGAAGA CATGAATGGT 
GCTTTCTCTG GGCTTGACAA ACTGAGGCGA CTGATACTCC AAGGAAATCG GATCCGTTCT 
ATTACTAAAA AAGCCTTCAC TGGTTTGGAT GCATTGGAGC ATCTAGACCT GAGTGACAAC 
GCAATCATGT CTTTACAAGG CAATGCATTT TCACAAATGA AGAAACTGCA ACAATTGCAT 
TTAAATACAT CAAGCCTTTT GTGCGATTGC CAGCTAAAAT GGCTCCCACA GTGGGTGGCG 
GAAAACAACT TTCAGAGCTT TGTAAATGCC AGTTGTGCCC ATCCTCAGCT GCTAAAAGGA 
AGAAGCATTT TTGCTGTTAG CCCAGATGGC TTTGTGTGTG ATGATTTTCC CAAACCCCAG 
ATCACGGTTC AGCCAGAAAC ACAGTCGGCA ATAAAAGGTT CCAATTTGAG TTTCATCTGC 
TCAGCTGCCA GCAGCAGTGA TTCCCCAATG ACTTTTGCTT GGAAAAAAGA CAATGAACTA 
CTGCATGATG CTGAAATGGA AAATTATGCA CACCTCCGGG CCCAAGGTGG CGAGGTGATG 
GAGTATACCA CCATCCTTCG GCTGCGCGAG GTGGAATTTG CCAGTGAGGG GAAATATCAG 
TGTGTCATCT CCAATCACTT TGGTTCATCC TACTCTGTCA AAGCCAAGCT TACAGTAAAT 
ATTCCCCACC TGACTCTTCC TTTCCCTACC TTTCATTCCA CAAAATTAAG ATTCTTGGTT 
ATTTGTATCT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

LRIG3 ( XM_017018790.2 ) cDNA ORF clone, Homo sapiens(human) -> XP_016874279.1 Homo sapiens leucine rich repeats and immunoglobulin like domains 3 (LRIG3), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OHu83514
Clone ID Related Accession (Same CDS sequence)	XM_017018790.1 , XM_017018790.2
Accession Version	XM_017018790.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1872bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	leucine-rich repeats and immunoglobulin-like domains protein 3 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000012.12) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Mar 26, 2018 this sequence version replaced XM_017018790.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGAGCGCGC CGAGCCTCCG TGCGCGCGCC GCGGGGTTGG GGCTGCTGCT GTGCGCGGTG 
CTGGGGCGCG CTGGCCGGTC AGACAGCGGC GGTCGCGGGG AACTCGGGCA GCCCTCTGGG 
GTAGCCGCCG AGCGCCCATG CCCCACTACC TGCCGCTGCC TCGGGGACCT GCTGGACTGC 
AGTCGTAAGC GGCTAGCGCG TCTTCCCGAG CCACTCCCGT CCTGGGTCGC TCGGCTGGAC 
TTAAGTCACA ACAGATTATC TTTCATCAAG GCAAGTTCCA TGAGCCACCT TCAAAGCCTT 
CGAGAAGTGA AACTGAACAA CAATGAATTG GAGACCATTC CAAATCTGGG ACCAGTCTCG 
GCAAATATTA CACTTCTCTC CTTGGCTGGA AACAGGATTG TTGAAATACT CCCTGAACAT 
CTGAAAGAGT TTCAGTCCCT TGAAACTTTG GACCTTAGCA GCAACAATAT TTCAGAGCTC 
CAAACTGCAT TTCCAGCCCT ACAGCTCAAA TATCTGTATC TCAACAGCAA CCGAGTCACA 
TCAATGGAAC CTGGGTATTT TGACAATTTG GCCAACACAC TCCTTGTGTT AAAGCTGAAC 
AGGAACCGAA TCTCAGCTAT CCCACCCAAG ATGTTTAAAC TGCCCCAACT GCAACATCTC 
GAATTGAACC GAAACAAGAT TAAAAATGTA GATGGACTGA CATTCCAAGG CCTTGGTGCT 
CTGAAGTCTC TGAAAATGCA AAGAAATGGA GTAACGAAAC TTATGGATGG AGCTTTTTGG 
GGGCTGAGCA ACATGGAAAT TTTGCAGCTG GACCATAACA ACCTAACAGA GATTACCAAA 
GGCTGGCTTT ACGGCTTGCT GATGCTGCAG GAACTTCATC TCAGCCAAAA TGCCATCAAC 
AGGATCAGCC CTGATGCCTG GGAGTTCTGC CAGAAGCTCA GTGAGCTGGA CCTAACTTTC 
AATCACTTAT CAAGGTTAGA TGATTCAAGC TTCCTTGGCC TAAGCTTACT AAATACACTG 
CACATTGGGA ACAACAGAGT CAGCTACATT GCTGATTGTG CCTTCCGGGG GCTTTCCAGT 
TTAAAGACTT TGGATCTGAA GAACAATGAA ATTTCCTGGA CTATTGAAGA CATGAATGGT 
GCTTTCTCTG GGCTTGACAA ACTGAGGCGA CTGATACTCC AAGGAAATCG GATCCGTTCT 
ATTACTAAAA AAGCCTTCAC TGGTTTGGAT GCATTGGAGC ATCTAGACCT GAGTGACAAC 
GCAATCATGT CTTTACAAGG CAATGCATTT TCACAAATGA AGAAACTGCA ACAATTGCAT 
TTAAATACAT CAAGCCTTTT GTGCGATTGC CAGCTAAAAT GGCTCCCACA GTGGGTGGCG 
GAAAACAACT TTCAGAGCTT TGTAAATGCC AGTTGTGCCC ATCCTCAGCT GCTAAAAGGA 
AGAAGCATTT TTGCTGTTAG CCCAGATGGC TTTGTGTGTG ATGATTTTCC CAAACCCCAG 
ATCACGGTTC AGCCAGAAAC ACAGTCGGCA ATAAAAGGTT CCAATTTGAG TTTCATCTGC 
TCAGCTGCCA GCAGCAGTGA TTCCCCAATG ACTTTTGCTT GGAAAAAAGA CAATGAACTA 
CTGCATGATG CTGAAATGGA AAATTATGCA CACCTCCGGG CCCAAGGTGG CGAGGTGATG 
GAGTATACCA CCATCCTTCG GCTGCGCGAG GTGGAATTTG CCAGTGAGGG GAAATATCAG 
TGTGTCATCT CCAATCACTT TGGTTCATCC TACTCTGTCA AAGCCAAGCT TACAGTAAAT 
ATTCCCCACC TGACTCTTCC TTTCCCTACC TTTCATTCCA CAAAATTAAG ATTCTTGGTT 
ATTTGTATCT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_016874279.1
CDS	285..2156
Translation	MSAPSLRARAAGLGLLLCAVLGRAGRSDSGGRGELGQPSGVAAERPCPTTCRCLGDLLDCSRKRLARLPEPLPSWVARLDLSHNRLSFIKASSMSHLQSLREVKLNNNELETIPNLGPVSANITLLSLAGNRIVEILPEHLKEFQSLETLDLSSNNISELQTAFPALQLKYLYLNSNRVTSMEPGYFDNLANTLLVLKLNRNRISAIPPKMFKLPQLQHLELNRNKIKNVDGLTFQGLGALKSLKMQRNGVTKLMDGAFWGLSNMEILQLDHNNLTEITKGWLYGLLMLQELHLSQNAINRISPDAWEFCQKLSELDLTFNHLSRLDDSSFLGLSLLNTLHIGNNRVSYIADCAFRGLSSLKTLDLKNNEISWTIEDMNGAFSGLDKLRRLILQGNRIRSITKKAFTGLDALEHLDLSDNAIMSLQGNAFSQMKKLQQLHLNTSSLLCDCQLKWLPQWVAENNFQSFVNASCAHPQLLKGRSIFAVSPDGFVCDDFPKPQITVQPETQSAIKGSNLSFICSAASSSDSPMTFAWKKDNELLHDAEMENYAHLRAQGGEVMEYTTILRLREVEFASEGKYQCVISNHFGSSYSVKAKLTVNIPHLTLPFPTFHSTKLRFLVICI

Target ORF information:

RefSeq Version	XM_017018790.2
Organism	Homo sapiens(human)
Definition	Homo sapiens leucine rich repeats and immunoglobulin like domains 3 (LRIG3), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017018790.2

ORF Insert Sequence:

ATGAGCGCGC CGAGCCTCCG TGCGCGCGCC GCGGGGTTGG GGCTGCTGCT GTGCGCGGTG 
CTGGGGCGCG CTGGCCGGTC AGACAGCGGC GGTCGCGGGG AACTCGGGCA GCCCTCTGGG 
GTAGCCGCCG AGCGCCCATG CCCCACTACC TGCCGCTGCC TCGGGGACCT GCTGGACTGC 
AGTCGTAAGC GGCTAGCGCG TCTTCCCGAG CCACTCCCGT CCTGGGTCGC TCGGCTGGAC 
TTAAGTCACA ACAGATTATC TTTCATCAAG GCAAGTTCCA TGAGCCACCT TCAAAGCCTT 
CGAGAAGTGA AACTGAACAA CAATGAATTG GAGACCATTC CAAATCTGGG ACCAGTCTCG 
GCAAATATTA CACTTCTCTC CTTGGCTGGA AACAGGATTG TTGAAATACT CCCTGAACAT 
CTGAAAGAGT TTCAGTCCCT TGAAACTTTG GACCTTAGCA GCAACAATAT TTCAGAGCTC 
CAAACTGCAT TTCCAGCCCT ACAGCTCAAA TATCTGTATC TCAACAGCAA CCGAGTCACA 
TCAATGGAAC CTGGGTATTT TGACAATTTG GCCAACACAC TCCTTGTGTT AAAGCTGAAC 
AGGAACCGAA TCTCAGCTAT CCCACCCAAG ATGTTTAAAC TGCCCCAACT GCAACATCTC 
GAATTGAACC GAAACAAGAT TAAAAATGTA GATGGACTGA CATTCCAAGG CCTTGGTGCT 
CTGAAGTCTC TGAAAATGCA AAGAAATGGA GTAACGAAAC TTATGGATGG AGCTTTTTGG 
GGGCTGAGCA ACATGGAAAT TTTGCAGCTG GACCATAACA ACCTAACAGA GATTACCAAA 
GGCTGGCTTT ACGGCTTGCT GATGCTGCAG GAACTTCATC TCAGCCAAAA TGCCATCAAC 
AGGATCAGCC CTGATGCCTG GGAGTTCTGC CAGAAGCTCA GTGAGCTGGA CCTAACTTTC 
AATCACTTAT CAAGGTTAGA TGATTCAAGC TTCCTTGGCC TAAGCTTACT AAATACACTG 
CACATTGGGA ACAACAGAGT CAGCTACATT GCTGATTGTG CCTTCCGGGG GCTTTCCAGT 
TTAAAGACTT TGGATCTGAA GAACAATGAA ATTTCCTGGA CTATTGAAGA CATGAATGGT 
GCTTTCTCTG GGCTTGACAA ACTGAGGCGA CTGATACTCC AAGGAAATCG GATCCGTTCT 
ATTACTAAAA AAGCCTTCAC TGGTTTGGAT GCATTGGAGC ATCTAGACCT GAGTGACAAC 
GCAATCATGT CTTTACAAGG CAATGCATTT TCACAAATGA AGAAACTGCA ACAATTGCAT 
TTAAATACAT CAAGCCTTTT GTGCGATTGC CAGCTAAAAT GGCTCCCACA GTGGGTGGCG 
GAAAACAACT TTCAGAGCTT TGTAAATGCC AGTTGTGCCC ATCCTCAGCT GCTAAAAGGA 
AGAAGCATTT TTGCTGTTAG CCCAGATGGC TTTGTGTGTG ATGATTTTCC CAAACCCCAG 
ATCACGGTTC AGCCAGAAAC ACAGTCGGCA ATAAAAGGTT CCAATTTGAG TTTCATCTGC 
TCAGCTGCCA GCAGCAGTGA TTCCCCAATG ACTTTTGCTT GGAAAAAAGA CAATGAACTA 
CTGCATGATG CTGAAATGGA AAATTATGCA CACCTCCGGG CCCAAGGTGG CGAGGTGATG 
GAGTATACCA CCATCCTTCG GCTGCGCGAG GTGGAATTTG CCAGTGAGGG GAAATATCAG 
TGTGTCATCT CCAATCACTT TGGTTCATCC TACTCTGTCA AAGCCAAGCT TACAGTAAAT 
ATTCCCCACC TGACTCTTCC TTTCCCTACC TTTCATTCCA CAAAATTAAG ATTCTTGGTT 
ATTTGTATCT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

LRIG3 ( NM_153377.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_700356.2 Homo sapiens leucine rich repeats and immunoglobulin like domains 3 (LRIG3), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu07008
Clone ID Related Accession (Same CDS sequence)	NM_153377.4
Accession Version	NM_153377.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 3360bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-28
Organism	Homo sapiens(human)
Product	leucine-rich repeats and immunoglobulin-like domains protein 3 isoform 2 precursor
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from DA456424.1, AK292857.1 and AY358288.1. On May 24, 2012 this sequence version replaced NM_153377.3. Transcript Variant: This variant (2) differs in the 5' UTR and 5' coding region and represents the use of an alternate promoter, compared to variant 1, which results in a protein (isoform 2) with a shorter and distinct N-terminus, compared to isoform 1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AY358288.1, SRR1803617.187879.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## ##RefSeq-Attributes-START## RefSeq Select criteria :: based on conservation, expression, longest protein ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGAGCGCGC CGAGCCTCCG TGCGCGCGCC GCGGGGTTGG GGCTGCTGCT GTGCGCGGTG 
CTGGGGCGCG CTGGCCGGTC AGACAGCGGC GGTCGCGGGG AACTCGGGCA GCCCTCTGGG 
GTAGCCGCCG AGCGCCCATG CCCCACTACC TGCCGCTGCC TCGGGGACCT GCTGGACTGC 
AGTCGTAAGC GGCTAGCGCG TCTTCCCGAG CCACTCCCGT CCTGGGTCGC TCGGCTGGAC 
TTAAGTCACA ACAGATTATC TTTCATCAAG GCAAGTTCCA TGAGCCACCT TCAAAGCCTT 
CGAGAAGTGA AACTGAACAA CAATGAATTG GAGACCATTC CAAATCTGGG ACCAGTCTCG 
GCAAATATTA CACTTCTCTC CTTGGCTGGA AACAGGATTG TTGAAATACT CCCTGAACAT 
CTGAAAGAGT TTCAGTCCCT TGAAACTTTG GACCTTAGCA GCAACAATAT TTCAGAGCTC 
CAAACTGCAT TTCCAGCCCT ACAGCTCAAA TATCTGTATC TCAACAGCAA CCGAGTCACA 
TCAATGGAAC CTGGGTATTT TGACAATTTG GCCAACACAC TCCTTGTGTT AAAGCTGAAC 
AGGAACCGAA TCTCAGCTAT CCCACCCAAG ATGTTTAAAC TGCCCCAACT GCAACATCTC 
GAATTGAACC GAAACAAGAT TAAAAATGTA GATGGACTGA CATTCCAAGG CCTTGGTGCT 
CTGAAGTCTC TGAAAATGCA AAGAAATGGA GTAACGAAAC TTATGGATGG AGCTTTTTGG 
GGGCTGAGCA ACATGGAAAT TTTGCAGCTG GACCATAACA ACCTAACAGA GATTACCAAA 
GGCTGGCTTT ACGGCTTGCT GATGCTGCAG GAACTTCATC TCAGCCAAAA TGCCATCAAC 
AGGATCAGCC CTGATGCCTG GGAGTTCTGC CAGAAGCTCA GTGAGCTGGA CCTAACTTTC 
AATCACTTAT CAAGGTTAGA TGATTCAAGC TTCCTTGGCC TAAGCTTACT AAATACACTG 
CACATTGGGA ACAACAGAGT CAGCTACATT GCTGATTGTG CCTTCCGGGG GCTTTCCAGT 
TTAAAGACTT TGGATCTGAA GAACAATGAA ATTTCCTGGA CTATTGAAGA CATGAATGGT 
GCTTTCTCTG GGCTTGACAA ACTGAGGCGA CTGATACTCC AAGGAAATCG GATCCGTTCT 
ATTACTAAAA AAGCCTTCAC TGGTTTGGAT GCATTGGAGC ATCTAGACCT GAGTGACAAC 
GCAATCATGT CTTTACAAGG CAATGCATTT TCACAAATGA AGAAACTGCA ACAATTGCAT 
TTAAATACAT CAAGCCTTTT GTGCGATTGC CAGCTAAAAT GGCTCCCACA GTGGGTGGCG 
GAAAACAACT TTCAGAGCTT TGTAAATGCC AGTTGTGCCC ATCCTCAGCT GCTAAAAGGA 
AGAAGCATTT TTGCTGTTAG CCCAGATGGC TTTGTGTGTG ATGATTTTCC CAAACCCCAG 
ATCACGGTTC AGCCAGAAAC ACAGTCGGCA ATAAAAGGTT CCAATTTGAG TTTCATCTGC 
TCAGCTGCCA GCAGCAGTGA TTCCCCAATG ACTTTTGCTT GGAAAAAAGA CAATGAACTA 
CTGCATGATG CTGAAATGGA AAATTATGCA CACCTCCGGG CCCAAGGTGG CGAGGTGATG 
GAGTATACCA CCATCCTTCG GCTGCGCGAG GTGGAATTTG CCAGTGAGGG GAAATATCAG 
TGTGTCATCT CCAATCACTT TGGTTCATCC TACTCTGTCA AAGCCAAGCT TACAGTAAAT 
ATGCTTCCCT CATTCACCAA GACCCCCATG GATCTCACCA TCCGAGCTGG GGCCATGGCA 
CGCTTGGAGT GTGCTGCTGT GGGGCACCCA GCCCCCCAGA TAGCCTGGCA GAAGGATGGG 
GGCACAGACT TCCCAGCTGC ACGGGAGAGA CGCATGCATG TGATGCCCGA GGATGACGTG 
TTCTTTATCG TGGATGTGAA GATAGAGGAC ATTGGGGTAT ACAGCTGCAC AGCTCAGAAC 
AGTGCAGGAA GTATTTCAGC AAATGCAACT CTGACTGTCC TAGAAACACC ATCATTTTTG 
CGGCCACTGT TGGACCGAAC TGTAACCAAG GGAGAAACAG CCGTCCTACA GTGCATTGCT 
GGAGGAAGCC CTCCCCCTAA ACTGAACTGG ACCAAAGATG ATAGCCCATT GGTGGTAACC 
GAGAGGCACT TTTTTGCAGC AGGCAATCAG CTTCTGATTA TTGTGGACTC AGATGTCAGT 
GATGCTGGGA AATACACATG TGAGATGTCT AACACCCTTG GCACTGAGAG AGGAAACGTG 
CGCCTCAGTG TGATCCCCAC TCCAACCTGC GACTCCCCTC AGATGACAGC CCCATCGTTA 
GACGATGACG GATGGGCCAC TGTGGGTGTC GTGATCATAG CCGTGGTTTG CTGTGTGGTG 
GGCACGTCAC TCGTGTGGGT GGTCATCATA TACCACACAA GGCGGAGGAA TGAAGATTGC 
AGCATTACCA ACACAGATGA GACCAACTTG CCAGCAGATA TTCCTAGTTA TTTGTCATCT 
CAGGGAACGT TAGCTGACAG GCAGGATGGG TACGTGTCTT CAGAAAGTGG AAGCCACCAC 
CAGTTTGTCA CATCTTCAGG TGCTGGATTT TTCTTACCAC AACATGACAG TAGTGGGACC 
TGCCATATTG ACAATAGCAG TGAAGCTGAT GTGGAAGCTG CCACAGATCT GTTCCTTTGT 
CCGTTTTTGG GATCCACAGG CCCTATGTAT TTGAAGGGAA ATGTGTATGG CTCAGATCCT 
TTTGAAACAT ATCATACAGG TTGCAGTCCT GACCCAAGAA CAGTTTTAAT GGACCACTAT 
GAGCCCAGTT ACATAAAGAA AAAGGAGTGC TACCCATGTT CTCATCCTTC AGAAGAATCC 
TGCGAACGGA GCTTCAGTAA TATATCGTGG CCTTCACATG TGAGGAAGCT ACTTAACACT 
AGTTACTCTC ACAATGAAGG ACCTGGAATG AAAAATCTGT GTCTAAACAA GTCCTCTTTA 
GATTTTAGTG CAAATCCAGA GCCAGCGTCG GTTGCCTCGA GTAATTCTTT CATGGGTACC 
TTTGGAAAAG CTCTCAGGAG ACCTCACCTA GATGCCTATT CAAGCTTTGG ACAGCCATCA 
GATTGTCAGC CAAGAGCCTT TTATTTGAAA GCTCATTCTT CCCCAGACTT GGACTCTGGG 
TCAGAGGAAG ATGGGAAAGA AAGGACAGAT TTTCAGGAAG AAAATCACAT TTGTACCTTT 
AAACAGACTT TAGAAAACTA CAGGACTCCA AATTTTCAGT CTTATGACTT GGACACATAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_700356.2
CDS	304..3663
Translation	MSAPSLRARAAGLGLLLCAVLGRAGRSDSGGRGELGQPSGVAAERPCPTTCRCLGDLLDCSRKRLARLPEPLPSWVARLDLSHNRLSFIKASSMSHLQSLREVKLNNNELETIPNLGPVSANITLLSLAGNRIVEILPEHLKEFQSLETLDLSSNNISELQTAFPALQLKYLYLNSNRVTSMEPGYFDNLANTLLVLKLNRNRISAIPPKMFKLPQLQHLELNRNKIKNVDGLTFQGLGALKSLKMQRNGVTKLMDGAFWGLSNMEILQLDHNNLTEITKGWLYGLLMLQELHLSQNAINRISPDAWEFCQKLSELDLTFNHLSRLDDSSFLGLSLLNTLHIGNNRVSYIADCAFRGLSSLKTLDLKNNEISWTIEDMNGAFSGLDKLRRLILQGNRIRSITKKAFTGLDALEHLDLSDNAIMSLQGNAFSQMKKLQQLHLNTSSLLCDCQLKWLPQWVAENNFQSFVNASCAHPQLLKGRSIFAVSPDGFVCDDFPKPQITVQPETQSAIKGSNLSFICSAASSSDSPMTFAWKKDNELLHDAEMENYAHLRAQGGEVMEYTTILRLREVEFASEGKYQCVISNHFGSSYSVKAKLTVNMLPSFTKTPMDLTIRAGAMARLECAAVGHPAPQIAWQKDGGTDFPAARERRMHVMPEDDVFFIVDVKIEDIGVYSCTAQNSAGSISANATLTVLETPSFLRPLLDRTVTKGETAVLQCIAGGSPPPKLNWTKDDSPLVVTERHFFAAGNQLLIIVDSDVSDAGKYTCEMSNTLGTERGNVRLSVIPTPTCDSPQMTAPSLDDDGWATVGVVIIAVVCCVVGTSLVWVVIIYHTRRRNEDCSITNTDETNLPADIPSYLSSQGTLADRQDGYVSSESGSHHQFVTSSGAGFFLPQHDSSGTCHIDNSSEADVEAATDLFLCPFLGSTGPMYLKGNVYGSDPFETYHTGCSPDPRTVLMDHYEPSYIKKKECYPCSHPSEESCERSFSNISWPSHVRKLLNTSYSHNEGPGMKNLCLNKSSLDFSANPEPASVASSNSFMGTFGKALRRPHLDAYSSFGQPSDCQPRAFYLKAHSSPDLDSGSEEDGKERTDFQEENHICTFKQTLENYRTPNFQSYDLDT

Target ORF information:

RefSeq Version	NM_153377.4
Organism	Homo sapiens(human)
Definition	Homo sapiens leucine rich repeats and immunoglobulin like domains 3 (LRIG3), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_153377.4

ORF Insert Sequence:

ATGAGCGCGC CGAGCCTCCG TGCGCGCGCC GCGGGGTTGG GGCTGCTGCT GTGCGCGGTG 
CTGGGGCGCG CTGGCCGGTC AGACAGCGGC GGTCGCGGGG AACTCGGGCA GCCCTCTGGG 
GTAGCCGCCG AGCGCCCATG CCCCACTACC TGCCGCTGCC TCGGGGACCT GCTGGACTGC 
AGTCGTAAGC GGCTAGCGCG TCTTCCCGAG CCACTCCCGT CCTGGGTCGC TCGGCTGGAC 
TTAAGTCACA ACAGATTATC TTTCATCAAG GCAAGTTCCA TGAGCCACCT TCAAAGCCTT 
CGAGAAGTGA AACTGAACAA CAATGAATTG GAGACCATTC CAAATCTGGG ACCAGTCTCG 
GCAAATATTA CACTTCTCTC CTTGGCTGGA AACAGGATTG TTGAAATACT CCCTGAACAT 
CTGAAAGAGT TTCAGTCCCT TGAAACTTTG GACCTTAGCA GCAACAATAT TTCAGAGCTC 
CAAACTGCAT TTCCAGCCCT ACAGCTCAAA TATCTGTATC TCAACAGCAA CCGAGTCACA 
TCAATGGAAC CTGGGTATTT TGACAATTTG GCCAACACAC TCCTTGTGTT AAAGCTGAAC 
AGGAACCGAA TCTCAGCTAT CCCACCCAAG ATGTTTAAAC TGCCCCAACT GCAACATCTC 
GAATTGAACC GAAACAAGAT TAAAAATGTA GATGGACTGA CATTCCAAGG CCTTGGTGCT 
CTGAAGTCTC TGAAAATGCA AAGAAATGGA GTAACGAAAC TTATGGATGG AGCTTTTTGG 
GGGCTGAGCA ACATGGAAAT TTTGCAGCTG GACCATAACA ACCTAACAGA GATTACCAAA 
GGCTGGCTTT ACGGCTTGCT GATGCTGCAG GAACTTCATC TCAGCCAAAA TGCCATCAAC 
AGGATCAGCC CTGATGCCTG GGAGTTCTGC CAGAAGCTCA GTGAGCTGGA CCTAACTTTC 
AATCACTTAT CAAGGTTAGA TGATTCAAGC TTCCTTGGCC TAAGCTTACT AAATACACTG 
CACATTGGGA ACAACAGAGT CAGCTACATT GCTGATTGTG CCTTCCGGGG GCTTTCCAGT 
TTAAAGACTT TGGATCTGAA GAACAATGAA ATTTCCTGGA CTATTGAAGA CATGAATGGT 
GCTTTCTCTG GGCTTGACAA ACTGAGGCGA CTGATACTCC AAGGAAATCG GATCCGTTCT 
ATTACTAAAA AAGCCTTCAC TGGTTTGGAT GCATTGGAGC ATCTAGACCT GAGTGACAAC 
GCAATCATGT CTTTACAAGG CAATGCATTT TCACAAATGA AGAAACTGCA ACAATTGCAT 
TTAAATACAT CAAGCCTTTT GTGCGATTGC CAGCTAAAAT GGCTCCCACA GTGGGTGGCG 
GAAAACAACT TTCAGAGCTT TGTAAATGCC AGTTGTGCCC ATCCTCAGCT GCTAAAAGGA 
AGAAGCATTT TTGCTGTTAG CCCAGATGGC TTTGTGTGTG ATGATTTTCC CAAACCCCAG 
ATCACGGTTC AGCCAGAAAC ACAGTCGGCA ATAAAAGGTT CCAATTTGAG TTTCATCTGC 
TCAGCTGCCA GCAGCAGTGA TTCCCCAATG ACTTTTGCTT GGAAAAAAGA CAATGAACTA 
CTGCATGATG CTGAAATGGA AAATTATGCA CACCTCCGGG CCCAAGGTGG CGAGGTGATG 
GAGTATACCA CCATCCTTCG GCTGCGCGAG GTGGAATTTG CCAGTGAGGG GAAATATCAG 
TGTGTCATCT CCAATCACTT TGGTTCATCC TACTCTGTCA AAGCCAAGCT TACAGTAAAT 
ATGCTTCCCT CATTCACCAA GACCCCCATG GATCTCACCA TCCGAGCTGG GGCCATGGCA 
CGCTTGGAGT GTGCTGCTGT GGGGCACCCA GCCCCCCAGA TAGCCTGGCA GAAGGATGGG 
GGCACAGACT TCCCAGCTGC ACGGGAGAGA CGCATGCATG TGATGCCCGA GGATGACGTG 
TTCTTTATCG TGGATGTGAA GATAGAGGAC ATTGGGGTAT ACAGCTGCAC AGCTCAGAAC 
AGTGCAGGAA GTATTTCAGC AAATGCAACT CTGACTGTCC TAGAAACACC ATCATTTTTG 
CGGCCACTGT TGGACCGAAC TGTAACCAAG GGAGAAACAG CCGTCCTACA GTGCATTGCT 
GGAGGAAGCC CTCCCCCTAA ACTGAACTGG ACCAAAGATG ATAGCCCATT GGTGGTAACC 
GAGAGGCACT TTTTTGCAGC AGGCAATCAG CTTCTGATTA TTGTGGACTC AGATGTCAGT 
GATGCTGGGA AATACACATG TGAGATGTCT AACACCCTTG GCACTGAGAG AGGAAACGTG 
CGCCTCAGTG TGATCCCCAC TCCAACCTGC GACTCCCCTC AGATGACAGC CCCATCGTTA 
GACGATGACG GATGGGCCAC TGTGGGTGTC GTGATCATAG CCGTGGTTTG CTGTGTGGTG 
GGCACGTCAC TCGTGTGGGT GGTCATCATA TACCACACAA GGCGGAGGAA TGAAGATTGC 
AGCATTACCA ACACAGATGA GACCAACTTG CCAGCAGATA TTCCTAGTTA TTTGTCATCT 
CAGGGAACGT TAGCTGACAG GCAGGATGGG TACGTGTCTT CAGAAAGTGG AAGCCACCAC 
CAGTTTGTCA CATCTTCAGG TGCTGGATTT TTCTTACCAC AACATGACAG TAGTGGGACC 
TGCCATATTG ACAATAGCAG TGAAGCTGAT GTGGAAGCTG CCACAGATCT GTTCCTTTGT 
CCGTTTTTGG GATCCACAGG CCCTATGTAT TTGAAGGGAA ATGTGTATGG CTCAGATCCT 
TTTGAAACAT ATCATACAGG TTGCAGTCCT GACCCAAGAA CAGTTTTAAT GGACCACTAT 
GAGCCCAGTT ACATAAAGAA AAAGGAGTGC TACCCATGTT CTCATCCTTC AGAAGAATCC 
TGCGAACGGA GCTTCAGTAA TATATCGTGG CCTTCACATG TGAGGAAGCT ACTTAACACT 
AGTTACTCTC ACAATGAAGG ACCTGGAATG AAAAATCTGT GTCTAAACAA GTCCTCTTTA 
GATTTTAGTG CAAATCCAGA GCCAGCGTCG GTTGCCTCGA GTAATTCTTT CATGGGTACC 
TTTGGAAAAG CTCTCAGGAG ACCTCACCTA GATGCCTATT CAAGCTTTGG ACAGCCATCA 
GATTGTCAGC CAAGAGCCTT TTATTTGAAA GCTCATTCTT CCCCAGACTT GGACTCTGGG 
TCAGAGGAAG ATGGGAAAGA AAGGACAGAT TTTCAGGAAG AAAATCACAT TTGTACCTTT 
AAACAGACTT TAGAAAACTA CAGGACTCCA AATTTTCAGT CTTATGACTT GGACACATAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

LRIG3 ( NM_001136051.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_001129523.1 Homo sapiens leucine rich repeats and immunoglobulin like domains 3 (LRIG3), transcript variant 1, mRNA.

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CloneID	OHu07391
Clone ID Related Accession (Same CDS sequence)	NM_001136051.2
Accession Version	NM_001136051.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 3180bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-27
Organism	Homo sapiens(human)
Product	leucine-rich repeats and immunoglobulin-like domains protein 3 isoform 1 precursor
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AY358295.1 and AY358288.1. On May 25, 2012 this sequence version replaced NM_001136051.1. Transcript Variant: This variant (1) represents the shorter transcript and encodes the shorter isoform (1). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AY358295.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGTGGACG TACTTCTGTT GTTCTCCCTC TGCTTGCTTT TTCACATTAG CAGACCGGAC 
TTAAGTCACA ACAGATTATC TTTCATCAAG GCAAGTTCCA TGAGCCACCT TCAAAGCCTT 
CGAGAAGTGA AACTGAACAA CAATGAATTG GAGACCATTC CAAATCTGGG ACCAGTCTCG 
GCAAATATTA CACTTCTCTC CTTGGCTGGA AACAGGATTG TTGAAATACT CCCTGAACAT 
CTGAAAGAGT TTCAGTCCCT TGAAACTTTG GACCTTAGCA GCAACAATAT TTCAGAGCTC 
CAAACTGCAT TTCCAGCCCT ACAGCTCAAA TATCTGTATC TCAACAGCAA CCGAGTCACA 
TCAATGGAAC CTGGGTATTT TGACAATTTG GCCAACACAC TCCTTGTGTT AAAGCTGAAC 
AGGAACCGAA TCTCAGCTAT CCCACCCAAG ATGTTTAAAC TGCCCCAACT GCAACATCTC 
GAATTGAACC GAAACAAGAT TAAAAATGTA GATGGACTGA CATTCCAAGG CCTTGGTGCT 
CTGAAGTCTC TGAAAATGCA AAGAAATGGA GTAACGAAAC TTATGGATGG AGCTTTTTGG 
GGGCTGAGCA ACATGGAAAT TTTGCAGCTG GACCATAACA ACCTAACAGA GATTACCAAA 
GGCTGGCTTT ACGGCTTGCT GATGCTGCAG GAACTTCATC TCAGCCAAAA TGCCATCAAC 
AGGATCAGCC CTGATGCCTG GGAGTTCTGC CAGAAGCTCA GTGAGCTGGA CCTAACTTTC 
AATCACTTAT CAAGGTTAGA TGATTCAAGC TTCCTTGGCC TAAGCTTACT AAATACACTG 
CACATTGGGA ACAACAGAGT CAGCTACATT GCTGATTGTG CCTTCCGGGG GCTTTCCAGT 
TTAAAGACTT TGGATCTGAA GAACAATGAA ATTTCCTGGA CTATTGAAGA CATGAATGGT 
GCTTTCTCTG GGCTTGACAA ACTGAGGCGA CTGATACTCC AAGGAAATCG GATCCGTTCT 
ATTACTAAAA AAGCCTTCAC TGGTTTGGAT GCATTGGAGC ATCTAGACCT GAGTGACAAC 
GCAATCATGT CTTTACAAGG CAATGCATTT TCACAAATGA AGAAACTGCA ACAATTGCAT 
TTAAATACAT CAAGCCTTTT GTGCGATTGC CAGCTAAAAT GGCTCCCACA GTGGGTGGCG 
GAAAACAACT TTCAGAGCTT TGTAAATGCC AGTTGTGCCC ATCCTCAGCT GCTAAAAGGA 
AGAAGCATTT TTGCTGTTAG CCCAGATGGC TTTGTGTGTG ATGATTTTCC CAAACCCCAG 
ATCACGGTTC AGCCAGAAAC ACAGTCGGCA ATAAAAGGTT CCAATTTGAG TTTCATCTGC 
TCAGCTGCCA GCAGCAGTGA TTCCCCAATG ACTTTTGCTT GGAAAAAAGA CAATGAACTA 
CTGCATGATG CTGAAATGGA AAATTATGCA CACCTCCGGG CCCAAGGTGG CGAGGTGATG 
GAGTATACCA CCATCCTTCG GCTGCGCGAG GTGGAATTTG CCAGTGAGGG GAAATATCAG 
TGTGTCATCT CCAATCACTT TGGTTCATCC TACTCTGTCA AAGCCAAGCT TACAGTAAAT 
ATGCTTCCCT CATTCACCAA GACCCCCATG GATCTCACCA TCCGAGCTGG GGCCATGGCA 
CGCTTGGAGT GTGCTGCTGT GGGGCACCCA GCCCCCCAGA TAGCCTGGCA GAAGGATGGG 
GGCACAGACT TCCCAGCTGC ACGGGAGAGA CGCATGCATG TGATGCCCGA GGATGACGTG 
TTCTTTATCG TGGATGTGAA GATAGAGGAC ATTGGGGTAT ACAGCTGCAC AGCTCAGAAC 
AGTGCAGGAA GTATTTCAGC AAATGCAACT CTGACTGTCC TAGAAACACC ATCATTTTTG 
CGGCCACTGT TGGACCGAAC TGTAACCAAG GGAGAAACAG CCGTCCTACA GTGCATTGCT 
GGAGGAAGCC CTCCCCCTAA ACTGAACTGG ACCAAAGATG ATAGCCCATT GGTGGTAACC 
GAGAGGCACT TTTTTGCAGC AGGCAATCAG CTTCTGATTA TTGTGGACTC AGATGTCAGT 
GATGCTGGGA AATACACATG TGAGATGTCT AACACCCTTG GCACTGAGAG AGGAAACGTG 
CGCCTCAGTG TGATCCCCAC TCCAACCTGC GACTCCCCTC AGATGACAGC CCCATCGTTA 
GACGATGACG GATGGGCCAC TGTGGGTGTC GTGATCATAG CCGTGGTTTG CTGTGTGGTG 
GGCACGTCAC TCGTGTGGGT GGTCATCATA TACCACACAA GGCGGAGGAA TGAAGATTGC 
AGCATTACCA ACACAGATGA GACCAACTTG CCAGCAGATA TTCCTAGTTA TTTGTCATCT 
CAGGGAACGT TAGCTGACAG GCAGGATGGG TACGTGTCTT CAGAAAGTGG AAGCCACCAC 
CAGTTTGTCA CATCTTCAGG TGCTGGATTT TTCTTACCAC AACATGACAG TAGTGGGACC 
TGCCATATTG ACAATAGCAG TGAAGCTGAT GTGGAAGCTG CCACAGATCT GTTCCTTTGT 
CCGTTTTTGG GATCCACAGG CCCTATGTAT TTGAAGGGAA ATGTGTATGG CTCAGATCCT 
TTTGAAACAT ATCATACAGG TTGCAGTCCT GACCCAAGAA CAGTTTTAAT GGACCACTAT 
GAGCCCAGTT ACATAAAGAA AAAGGAGTGC TACCCATGTT CTCATCCTTC AGAAGAATCC 
TGCGAACGGA GCTTCAGTAA TATATCGTGG CCTTCACATG TGAGGAAGCT ACTTAACACT 
AGTTACTCTC ACAATGAAGG ACCTGGAATG AAAAATCTGT GTCTAAACAA GTCCTCTTTA 
GATTTTAGTG CAAATCCAGA GCCAGCGTCG GTTGCCTCGA GTAATTCTTT CATGGGTACC 
TTTGGAAAAG CTCTCAGGAG ACCTCACCTA GATGCCTATT CAAGCTTTGG ACAGCCATCA 
GATTGTCAGC CAAGAGCCTT TTATTTGAAA GCTCATTCTT CCCCAGACTT GGACTCTGGG 
TCAGAGGAAG ATGGGAAAGA AAGGACAGAT TTTCAGGAAG AAAATCACAT TTGTACCTTT 
AAACAGACTT TAGAAAACTA CAGGACTCCA AATTTTCAGT CTTATGACTT GGACACATAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001129523.1
CDS	65..3244
Translation	MVDVLLLFSLCLLFHISRPDLSHNRLSFIKASSMSHLQSLREVKLNNNELETIPNLGPVSANITLLSLAGNRIVEILPEHLKEFQSLETLDLSSNNISELQTAFPALQLKYLYLNSNRVTSMEPGYFDNLANTLLVLKLNRNRISAIPPKMFKLPQLQHLELNRNKIKNVDGLTFQGLGALKSLKMQRNGVTKLMDGAFWGLSNMEILQLDHNNLTEITKGWLYGLLMLQELHLSQNAINRISPDAWEFCQKLSELDLTFNHLSRLDDSSFLGLSLLNTLHIGNNRVSYIADCAFRGLSSLKTLDLKNNEISWTIEDMNGAFSGLDKLRRLILQGNRIRSITKKAFTGLDALEHLDLSDNAIMSLQGNAFSQMKKLQQLHLNTSSLLCDCQLKWLPQWVAENNFQSFVNASCAHPQLLKGRSIFAVSPDGFVCDDFPKPQITVQPETQSAIKGSNLSFICSAASSSDSPMTFAWKKDNELLHDAEMENYAHLRAQGGEVMEYTTILRLREVEFASEGKYQCVISNHFGSSYSVKAKLTVNMLPSFTKTPMDLTIRAGAMARLECAAVGHPAPQIAWQKDGGTDFPAARERRMHVMPEDDVFFIVDVKIEDIGVYSCTAQNSAGSISANATLTVLETPSFLRPLLDRTVTKGETAVLQCIAGGSPPPKLNWTKDDSPLVVTERHFFAAGNQLLIIVDSDVSDAGKYTCEMSNTLGTERGNVRLSVIPTPTCDSPQMTAPSLDDDGWATVGVVIIAVVCCVVGTSLVWVVIIYHTRRRNEDCSITNTDETNLPADIPSYLSSQGTLADRQDGYVSSESGSHHQFVTSSGAGFFLPQHDSSGTCHIDNSSEADVEAATDLFLCPFLGSTGPMYLKGNVYGSDPFETYHTGCSPDPRTVLMDHYEPSYIKKKECYPCSHPSEESCERSFSNISWPSHVRKLLNTSYSHNEGPGMKNLCLNKSSLDFSANPEPASVASSNSFMGTFGKALRRPHLDAYSSFGQPSDCQPRAFYLKAHSSPDLDSGSEEDGKERTDFQEENHICTFKQTLENYRTPNFQSYDLDT

Target ORF information:

RefSeq Version	NM_001136051.2
Organism	Homo sapiens(human)
Definition	Homo sapiens leucine rich repeats and immunoglobulin like domains 3 (LRIG3), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001136051.2

ORF Insert Sequence:

ATGGTGGACG TACTTCTGTT GTTCTCCCTC TGCTTGCTTT TTCACATTAG CAGACCGGAC 
TTAAGTCACA ACAGATTATC TTTCATCAAG GCAAGTTCCA TGAGCCACCT TCAAAGCCTT 
CGAGAAGTGA AACTGAACAA CAATGAATTG GAGACCATTC CAAATCTGGG ACCAGTCTCG 
GCAAATATTA CACTTCTCTC CTTGGCTGGA AACAGGATTG TTGAAATACT CCCTGAACAT 
CTGAAAGAGT TTCAGTCCCT TGAAACTTTG GACCTTAGCA GCAACAATAT TTCAGAGCTC 
CAAACTGCAT TTCCAGCCCT ACAGCTCAAA TATCTGTATC TCAACAGCAA CCGAGTCACA 
TCAATGGAAC CTGGGTATTT TGACAATTTG GCCAACACAC TCCTTGTGTT AAAGCTGAAC 
AGGAACCGAA TCTCAGCTAT CCCACCCAAG ATGTTTAAAC TGCCCCAACT GCAACATCTC 
GAATTGAACC GAAACAAGAT TAAAAATGTA GATGGACTGA CATTCCAAGG CCTTGGTGCT 
CTGAAGTCTC TGAAAATGCA AAGAAATGGA GTAACGAAAC TTATGGATGG AGCTTTTTGG 
GGGCTGAGCA ACATGGAAAT TTTGCAGCTG GACCATAACA ACCTAACAGA GATTACCAAA 
GGCTGGCTTT ACGGCTTGCT GATGCTGCAG GAACTTCATC TCAGCCAAAA TGCCATCAAC 
AGGATCAGCC CTGATGCCTG GGAGTTCTGC CAGAAGCTCA GTGAGCTGGA CCTAACTTTC 
AATCACTTAT CAAGGTTAGA TGATTCAAGC TTCCTTGGCC TAAGCTTACT AAATACACTG 
CACATTGGGA ACAACAGAGT CAGCTACATT GCTGATTGTG CCTTCCGGGG GCTTTCCAGT 
TTAAAGACTT TGGATCTGAA GAACAATGAA ATTTCCTGGA CTATTGAAGA CATGAATGGT 
GCTTTCTCTG GGCTTGACAA ACTGAGGCGA CTGATACTCC AAGGAAATCG GATCCGTTCT 
ATTACTAAAA AAGCCTTCAC TGGTTTGGAT GCATTGGAGC ATCTAGACCT GAGTGACAAC 
GCAATCATGT CTTTACAAGG CAATGCATTT TCACAAATGA AGAAACTGCA ACAATTGCAT 
TTAAATACAT CAAGCCTTTT GTGCGATTGC CAGCTAAAAT GGCTCCCACA GTGGGTGGCG 
GAAAACAACT TTCAGAGCTT TGTAAATGCC AGTTGTGCCC ATCCTCAGCT GCTAAAAGGA 
AGAAGCATTT TTGCTGTTAG CCCAGATGGC TTTGTGTGTG ATGATTTTCC CAAACCCCAG 
ATCACGGTTC AGCCAGAAAC ACAGTCGGCA ATAAAAGGTT CCAATTTGAG TTTCATCTGC 
TCAGCTGCCA GCAGCAGTGA TTCCCCAATG ACTTTTGCTT GGAAAAAAGA CAATGAACTA 
CTGCATGATG CTGAAATGGA AAATTATGCA CACCTCCGGG CCCAAGGTGG CGAGGTGATG 
GAGTATACCA CCATCCTTCG GCTGCGCGAG GTGGAATTTG CCAGTGAGGG GAAATATCAG 
TGTGTCATCT CCAATCACTT TGGTTCATCC TACTCTGTCA AAGCCAAGCT TACAGTAAAT 
ATGCTTCCCT CATTCACCAA GACCCCCATG GATCTCACCA TCCGAGCTGG GGCCATGGCA 
CGCTTGGAGT GTGCTGCTGT GGGGCACCCA GCCCCCCAGA TAGCCTGGCA GAAGGATGGG 
GGCACAGACT TCCCAGCTGC ACGGGAGAGA CGCATGCATG TGATGCCCGA GGATGACGTG 
TTCTTTATCG TGGATGTGAA GATAGAGGAC ATTGGGGTAT ACAGCTGCAC AGCTCAGAAC 
AGTGCAGGAA GTATTTCAGC AAATGCAACT CTGACTGTCC TAGAAACACC ATCATTTTTG 
CGGCCACTGT TGGACCGAAC TGTAACCAAG GGAGAAACAG CCGTCCTACA GTGCATTGCT 
GGAGGAAGCC CTCCCCCTAA ACTGAACTGG ACCAAAGATG ATAGCCCATT GGTGGTAACC 
GAGAGGCACT TTTTTGCAGC AGGCAATCAG CTTCTGATTA TTGTGGACTC AGATGTCAGT 
GATGCTGGGA AATACACATG TGAGATGTCT AACACCCTTG GCACTGAGAG AGGAAACGTG 
CGCCTCAGTG TGATCCCCAC TCCAACCTGC GACTCCCCTC AGATGACAGC CCCATCGTTA 
GACGATGACG GATGGGCCAC TGTGGGTGTC GTGATCATAG CCGTGGTTTG CTGTGTGGTG 
GGCACGTCAC TCGTGTGGGT GGTCATCATA TACCACACAA GGCGGAGGAA TGAAGATTGC 
AGCATTACCA ACACAGATGA GACCAACTTG CCAGCAGATA TTCCTAGTTA TTTGTCATCT 
CAGGGAACGT TAGCTGACAG GCAGGATGGG TACGTGTCTT CAGAAAGTGG AAGCCACCAC 
CAGTTTGTCA CATCTTCAGG TGCTGGATTT TTCTTACCAC AACATGACAG TAGTGGGACC 
TGCCATATTG ACAATAGCAG TGAAGCTGAT GTGGAAGCTG CCACAGATCT GTTCCTTTGT 
CCGTTTTTGG GATCCACAGG CCCTATGTAT TTGAAGGGAA ATGTGTATGG CTCAGATCCT 
TTTGAAACAT ATCATACAGG TTGCAGTCCT GACCCAAGAA CAGTTTTAAT GGACCACTAT 
GAGCCCAGTT ACATAAAGAA AAAGGAGTGC TACCCATGTT CTCATCCTTC AGAAGAATCC 
TGCGAACGGA GCTTCAGTAA TATATCGTGG CCTTCACATG TGAGGAAGCT ACTTAACACT 
AGTTACTCTC ACAATGAAGG ACCTGGAATG AAAAATCTGT GTCTAAACAA GTCCTCTTTA 
GATTTTAGTG CAAATCCAGA GCCAGCGTCG GTTGCCTCGA GTAATTCTTT CATGGGTACC 
TTTGGAAAAG CTCTCAGGAG ACCTCACCTA GATGCCTATT CAAGCTTTGG ACAGCCATCA 
GATTGTCAGC CAAGAGCCTT TTATTTGAAA GCTCATTCTT CCCCAGACTT GGACTCTGGG 
TCAGAGGAAG ATGGGAAAGA AAGGACAGAT TTTCAGGAAG AAAATCACAT TTGTACCTTT 
AAACAGACTT TAGAAAACTA CAGGACTCCA AATTTTCAGT CTTATGACTT GGACACATAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

LRIG3 ( XM_011537893.2 ) cDNA ORF clone, Homo sapiens(human) -> XP_011536195.1 Homo sapiens leucine-rich repeats and immunoglobulin like domains 3 (LRIG3), transcript variant X1, mRNA.

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CloneID	OHu75145
Clone ID Related Accession (Same CDS sequence)	XM_011537893.2
Accession Version	XM_011537893.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 3126bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-06-05
Organism	Homo sapiens(human)
Product	leucine-rich repeats and immunoglobulin-like domains protein 3 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000012.12) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 6, 2016 this sequence version replaced XM_011537893.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGACTTAA GTCACAACAG ATTATCTTTC ATCAAGGCAA GTTCCATGAG CCACCTTCAA 
AGCCTTCGAG AAGTGAAACT GAACAACAAT GAATTGGAGA CCATTCCAAA TCTGGGACCA 
GTCTCGGCAA ATATTACACT TCTCTCCTTG GCTGGAAACA GGATTGTTGA AATACTCCCT 
GAACATCTGA AAGAGTTTCA GTCCCTTGAA ACTTTGGACC TTAGCAGCAA CAATATTTCA 
GAGCTCCAAA CTGCATTTCC AGCCCTACAG CTCAAATATC TGTATCTCAA CAGCAACCGA 
GTCACATCAA TGGAACCTGG GTATTTTGAC AATTTGGCCA ACACACTCCT TGTGTTAAAG 
CTGAACAGGA ACCGAATCTC AGCTATCCCA CCCAAGATGT TTAAACTGCC CCAACTGCAA 
CATCTCGAAT TGAACCGAAA CAAGATTAAA AATGTAGATG GACTGACATT CCAAGGCCTT 
GGTGCTCTGA AGTCTCTGAA AATGCAAAGA AATGGAGTAA CGAAACTTAT GGATGGAGCT 
TTTTGGGGGC TGAGCAACAT GGAAATTTTG CAGCTGGACC ATAACAACCT AACAGAGATT 
ACCAAAGGCT GGCTTTACGG CTTGCTGATG CTGCAGGAAC TTCATCTCAG CCAAAATGCC 
ATCAACAGGA TCAGCCCTGA TGCCTGGGAG TTCTGCCAGA AGCTCAGTGA GCTGGACCTA 
ACTTTCAATC ACTTATCAAG GTTAGATGAT TCAAGCTTCC TTGGCCTAAG CTTACTAAAT 
ACACTGCACA TTGGGAACAA CAGAGTCAGC TACATTGCTG ATTGTGCCTT CCGGGGGCTT 
TCCAGTTTAA AGACTTTGGA TCTGAAGAAC AATGAAATTT CCTGGACTAT TGAAGACATG 
AATGGTGCTT TCTCTGGGCT TGACAAACTG AGGCGACTGA TACTCCAAGG AAATCGGATC 
CGTTCTATTA CTAAAAAAGC CTTCACTGGT TTGGATGCAT TGGAGCATCT AGACCTGAGT 
GACAACGCAA TCATGTCTTT ACAAGGCAAT GCATTTTCAC AAATGAAGAA ACTGCAACAA 
TTGCATTTAA ATACATCAAG CCTTTTGTGC GATTGCCAGC TAAAATGGCT CCCACAGTGG 
GTGGCGGAAA ACAACTTTCA GAGCTTTGTA AATGCCAGTT GTGCCCATCC TCAGCTGCTA 
AAAGGAAGAA GCATTTTTGC TGTTAGCCCA GATGGCTTTG TGTGTGATGA TTTTCCCAAA 
CCCCAGATCA CGGTTCAGCC AGAAACACAG TCGGCAATAA AAGGTTCCAA TTTGAGTTTC 
ATCTGCTCAG CTGCCAGCAG CAGTGATTCC CCAATGACTT TTGCTTGGAA AAAAGACAAT 
GAACTACTGC ATGATGCTGA AATGGAAAAT TATGCACACC TCCGGGCCCA AGGTGGCGAG 
GTGATGGAGT ATACCACCAT CCTTCGGCTG CGCGAGGTGG AATTTGCCAG TGAGGGGAAA 
TATCAGTGTG TCATCTCCAA TCACTTTGGT TCATCCTACT CTGTCAAAGC CAAGCTTACA 
GTAAATATGC TTCCCTCATT CACCAAGACC CCCATGGATC TCACCATCCG AGCTGGGGCC 
ATGGCACGCT TGGAGTGTGC TGCTGTGGGG CACCCAGCCC CCCAGATAGC CTGGCAGAAG 
GATGGGGGCA CAGACTTCCC AGCTGCACGG GAGAGACGCA TGCATGTGAT GCCCGAGGAT 
GACGTGTTCT TTATCGTGGA TGTGAAGATA GAGGACATTG GGGTATACAG CTGCACAGCT 
CAGAACAGTG CAGGAAGTAT TTCAGCAAAT GCAACTCTGA CTGTCCTAGA AACACCATCA 
TTTTTGCGGC CACTGTTGGA CCGAACTGTA ACCAAGGGAG AAACAGCCGT CCTACAGTGC 
ATTGCTGGAG GAAGCCCTCC CCCTAAACTG AACTGGACCA AAGATGATAG CCCATTGGTG 
GTAACCGAGA GGCACTTTTT TGCAGCAGGC AATCAGCTTC TGATTATTGT GGACTCAGAT 
GTCAGTGATG CTGGGAAATA CACATGTGAG ATGTCTAACA CCCTTGGCAC TGAGAGAGGA 
AACGTGCGCC TCAGTGTGAT CCCCACTCCA ACCTGCGACT CCCCTCAGAT GACAGCCCCA 
TCGTTAGACG ATGACGGATG GGCCACTGTG GGTGTCGTGA TCATAGCCGT GGTTTGCTGT 
GTGGTGGGCA CGTCACTCGT GTGGGTGGTC ATCATATACC ACACAAGGCG GAGGAATGAA 
GATTGCAGCA TTACCAACAC AGATGAGACC AACTTGCCAG CAGATATTCC TAGTTATTTG 
TCATCTCAGG GAACGTTAGC TGACAGGCAG GATGGGTACG TGTCTTCAGA AAGTGGAAGC 
CACCACCAGT TTGTCACATC TTCAGGTGCT GGATTTTTCT TACCACAACA TGACAGTAGT 
GGGACCTGCC ATATTGACAA TAGCAGTGAA GCTGATGTGG AAGCTGCCAC AGATCTGTTC 
CTTTGTCCGT TTTTGGGATC CACAGGCCCT ATGTATTTGA AGGGAAATGT GTATGGCTCA 
GATCCTTTTG AAACATATCA TACAGGTTGC AGTCCTGACC CAAGAACAGT TTTAATGGAC 
CACTATGAGC CCAGTTACAT AAAGAAAAAG GAGTGCTACC CATGTTCTCA TCCTTCAGAA 
GAATCCTGCG AACGGAGCTT CAGTAATATA TCGTGGCCTT CACATGTGAG GAAGCTACTT 
AACACTAGTT ACTCTCACAA TGAAGGACCT GGAATGAAAA ATCTGTGTCT AAACAAGTCC 
TCTTTAGATT TTAGTGCAAA TCCAGAGCCA GCGTCGGTTG CCTCGAGTAA TTCTTTCATG 
GGTACCTTTG GAAAAGCTCT CAGGAGACCT CACCTAGATG CCTATTCAAG CTTTGGACAG 
CCATCAGATT GTCAGCCAAG AGCCTTTTAT TTGAAAGCTC ATTCTTCCCC AGACTTGGAC 
TCTGGGTCAG AGGAAGATGG GAAAGAAAGG ACAGATTTTC AGGAAGAAAA TCACATTTGT 
ACCTTTAAAC AGACTTTAGA AAACTACAGG ACTCCAAATT TTCAGTCTTA TGACTTGGAC 
ACATAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_011536195.1
CDS	210..3335
Translation	MDLSHNRLSFIKASSMSHLQSLREVKLNNNELETIPNLGPVSANITLLSLAGNRIVEILPEHLKEFQSLETLDLSSNNISELQTAFPALQLKYLYLNSNRVTSMEPGYFDNLANTLLVLKLNRNRISAIPPKMFKLPQLQHLELNRNKIKNVDGLTFQGLGALKSLKMQRNGVTKLMDGAFWGLSNMEILQLDHNNLTEITKGWLYGLLMLQELHLSQNAINRISPDAWEFCQKLSELDLTFNHLSRLDDSSFLGLSLLNTLHIGNNRVSYIADCAFRGLSSLKTLDLKNNEISWTIEDMNGAFSGLDKLRRLILQGNRIRSITKKAFTGLDALEHLDLSDNAIMSLQGNAFSQMKKLQQLHLNTSSLLCDCQLKWLPQWVAENNFQSFVNASCAHPQLLKGRSIFAVSPDGFVCDDFPKPQITVQPETQSAIKGSNLSFICSAASSSDSPMTFAWKKDNELLHDAEMENYAHLRAQGGEVMEYTTILRLREVEFASEGKYQCVISNHFGSSYSVKAKLTVNMLPSFTKTPMDLTIRAGAMARLECAAVGHPAPQIAWQKDGGTDFPAARERRMHVMPEDDVFFIVDVKIEDIGVYSCTAQNSAGSISANATLTVLETPSFLRPLLDRTVTKGETAVLQCIAGGSPPPKLNWTKDDSPLVVTERHFFAAGNQLLIIVDSDVSDAGKYTCEMSNTLGTERGNVRLSVIPTPTCDSPQMTAPSLDDDGWATVGVVIIAVVCCVVGTSLVWVVIIYHTRRRNEDCSITNTDETNLPADIPSYLSSQGTLADRQDGYVSSESGSHHQFVTSSGAGFFLPQHDSSGTCHIDNSSEADVEAATDLFLCPFLGSTGPMYLKGNVYGSDPFETYHTGCSPDPRTVLMDHYEPSYIKKKECYPCSHPSEESCERSFSNISWPSHVRKLLNTSYSHNEGPGMKNLCLNKSSLDFSANPEPASVASSNSFMGTFGKALRRPHLDAYSSFGQPSDCQPRAFYLKAHSSPDLDSGSEEDGKERTDFQEENHICTFKQTLENYRTPNFQSYDLDT

Target ORF information:

RefSeq Version	XM_011537893.2
Organism	Homo sapiens(human)
Definition	Homo sapiens leucine-rich repeats and immunoglobulin like domains 3 (LRIG3), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011537893.2

ORF Insert Sequence:

ATGGACTTAA GTCACAACAG ATTATCTTTC ATCAAGGCAA GTTCCATGAG CCACCTTCAA 
AGCCTTCGAG AAGTGAAACT GAACAACAAT GAATTGGAGA CCATTCCAAA TCTGGGACCA 
GTCTCGGCAA ATATTACACT TCTCTCCTTG GCTGGAAACA GGATTGTTGA AATACTCCCT 
GAACATCTGA AAGAGTTTCA GTCCCTTGAA ACTTTGGACC TTAGCAGCAA CAATATTTCA 
GAGCTCCAAA CTGCATTTCC AGCCCTACAG CTCAAATATC TGTATCTCAA CAGCAACCGA 
GTCACATCAA TGGAACCTGG GTATTTTGAC AATTTGGCCA ACACACTCCT TGTGTTAAAG 
CTGAACAGGA ACCGAATCTC AGCTATCCCA CCCAAGATGT TTAAACTGCC CCAACTGCAA 
CATCTCGAAT TGAACCGAAA CAAGATTAAA AATGTAGATG GACTGACATT CCAAGGCCTT 
GGTGCTCTGA AGTCTCTGAA AATGCAAAGA AATGGAGTAA CGAAACTTAT GGATGGAGCT 
TTTTGGGGGC TGAGCAACAT GGAAATTTTG CAGCTGGACC ATAACAACCT AACAGAGATT 
ACCAAAGGCT GGCTTTACGG CTTGCTGATG CTGCAGGAAC TTCATCTCAG CCAAAATGCC 
ATCAACAGGA TCAGCCCTGA TGCCTGGGAG TTCTGCCAGA AGCTCAGTGA GCTGGACCTA 
ACTTTCAATC ACTTATCAAG GTTAGATGAT TCAAGCTTCC TTGGCCTAAG CTTACTAAAT 
ACACTGCACA TTGGGAACAA CAGAGTCAGC TACATTGCTG ATTGTGCCTT CCGGGGGCTT 
TCCAGTTTAA AGACTTTGGA TCTGAAGAAC AATGAAATTT CCTGGACTAT TGAAGACATG 
AATGGTGCTT TCTCTGGGCT TGACAAACTG AGGCGACTGA TACTCCAAGG AAATCGGATC 
CGTTCTATTA CTAAAAAAGC CTTCACTGGT TTGGATGCAT TGGAGCATCT AGACCTGAGT 
GACAACGCAA TCATGTCTTT ACAAGGCAAT GCATTTTCAC AAATGAAGAA ACTGCAACAA 
TTGCATTTAA ATACATCAAG CCTTTTGTGC GATTGCCAGC TAAAATGGCT CCCACAGTGG 
GTGGCGGAAA ACAACTTTCA GAGCTTTGTA AATGCCAGTT GTGCCCATCC TCAGCTGCTA 
AAAGGAAGAA GCATTTTTGC TGTTAGCCCA GATGGCTTTG TGTGTGATGA TTTTCCCAAA 
CCCCAGATCA CGGTTCAGCC AGAAACACAG TCGGCAATAA AAGGTTCCAA TTTGAGTTTC 
ATCTGCTCAG CTGCCAGCAG CAGTGATTCC CCAATGACTT TTGCTTGGAA AAAAGACAAT 
GAACTACTGC ATGATGCTGA AATGGAAAAT TATGCACACC TCCGGGCCCA AGGTGGCGAG 
GTGATGGAGT ATACCACCAT CCTTCGGCTG CGCGAGGTGG AATTTGCCAG TGAGGGGAAA 
TATCAGTGTG TCATCTCCAA TCACTTTGGT TCATCCTACT CTGTCAAAGC CAAGCTTACA 
GTAAATATGC TTCCCTCATT CACCAAGACC CCCATGGATC TCACCATCCG AGCTGGGGCC 
ATGGCACGCT TGGAGTGTGC TGCTGTGGGG CACCCAGCCC CCCAGATAGC CTGGCAGAAG 
GATGGGGGCA CAGACTTCCC AGCTGCACGG GAGAGACGCA TGCATGTGAT GCCCGAGGAT 
GACGTGTTCT TTATCGTGGA TGTGAAGATA GAGGACATTG GGGTATACAG CTGCACAGCT 
CAGAACAGTG CAGGAAGTAT TTCAGCAAAT GCAACTCTGA CTGTCCTAGA AACACCATCA 
TTTTTGCGGC CACTGTTGGA CCGAACTGTA ACCAAGGGAG AAACAGCCGT CCTACAGTGC 
ATTGCTGGAG GAAGCCCTCC CCCTAAACTG AACTGGACCA AAGATGATAG CCCATTGGTG 
GTAACCGAGA GGCACTTTTT TGCAGCAGGC AATCAGCTTC TGATTATTGT GGACTCAGAT 
GTCAGTGATG CTGGGAAATA CACATGTGAG ATGTCTAACA CCCTTGGCAC TGAGAGAGGA 
AACGTGCGCC TCAGTGTGAT CCCCACTCCA ACCTGCGACT CCCCTCAGAT GACAGCCCCA 
TCGTTAGACG ATGACGGATG GGCCACTGTG GGTGTCGTGA TCATAGCCGT GGTTTGCTGT 
GTGGTGGGCA CGTCACTCGT GTGGGTGGTC ATCATATACC ACACAAGGCG GAGGAATGAA 
GATTGCAGCA TTACCAACAC AGATGAGACC AACTTGCCAG CAGATATTCC TAGTTATTTG 
TCATCTCAGG GAACGTTAGC TGACAGGCAG GATGGGTACG TGTCTTCAGA AAGTGGAAGC 
CACCACCAGT TTGTCACATC TTCAGGTGCT GGATTTTTCT TACCACAACA TGACAGTAGT 
GGGACCTGCC ATATTGACAA TAGCAGTGAA GCTGATGTGG AAGCTGCCAC AGATCTGTTC 
CTTTGTCCGT TTTTGGGATC CACAGGCCCT ATGTATTTGA AGGGAAATGT GTATGGCTCA 
GATCCTTTTG AAACATATCA TACAGGTTGC AGTCCTGACC CAAGAACAGT TTTAATGGAC 
CACTATGAGC CCAGTTACAT AAAGAAAAAG GAGTGCTACC CATGTTCTCA TCCTTCAGAA 
GAATCCTGCG AACGGAGCTT CAGTAATATA TCGTGGCCTT CACATGTGAG GAAGCTACTT 
AACACTAGTT ACTCTCACAA TGAAGGACCT GGAATGAAAA ATCTGTGTCT AAACAAGTCC 
TCTTTAGATT TTAGTGCAAA TCCAGAGCCA GCGTCGGTTG CCTCGAGTAA TTCTTTCATG 
GGTACCTTTG GAAAAGCTCT CAGGAGACCT CACCTAGATG CCTATTCAAG CTTTGGACAG 
CCATCAGATT GTCAGCCAAG AGCCTTTTAT TTGAAAGCTC ATTCTTCCCC AGACTTGGAC 
TCTGGGTCAG AGGAAGATGG GAAAGAAAGG ACAGATTTTC AGGAAGAAAA TCACATTTGT 
ACCTTTAAAC AGACTTTAGA AAACTACAGG ACTCCAAATT TTCAGTCTTA TGACTTGGAC 
ACATAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

LRIGs: A Prognostically Significant Family with Emerging Therapeutic Competence against Cancers.
Current cancer drug targets17(1)3-16(2017)
Malik U,Javed A

Variants in the genes DCTN2, DNAH10, LRIG3, and MYO1A are associated with intermediate Charcot-Marie-Tooth disease in a Norwegian family.
Acta neurologica Scandinavica134(1)67-75(2016 Jul)
Braathen GJ,H?yer H,Busk ?L,Tveten K,Skjelbred CF,Russell MB

LRIG3 modulates proliferation, apoptosis and invasion of glioblastoma cells as a potent tumor suppressor.
Journal of the neurological sciences350(1-2)61-8(2015 Mar)
Guo D,Yang H,Guo Y,Xiao Q,Mao F,Tan Y,Wan X,Wang B,Lei T

Expression and significance of LRIG3 in human cervical squamous cell carcinoma.
European journal of gynaecological oncology36(4)414-9(2015)
Guo L,Zhang W,Sheng Y,Chen K,Shi Q,Zhang P,Zhang R

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LRIG3 cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

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Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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