Gene Symbol | LRRK2 |
Entrez Gene ID | 120892 |
Full Name | leucine rich repeat kinase 2 |
Synonyms | AURA17,DARDARIN,PARK8,RIPK7,ROCO2 |
General protein information |
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Gene Type | protein-coding |
Organism | Homo sapiens(human) |
Genome | |
Summary | This gene is a member of the leucine-rich repeat kinase family and encodes a protein with an ankryin repeat region, a leucine-rich repeat (LRR) domain, a kinase domain, a DFG-like motif, a RAS domain, a GTPase domain, a MLK-like domain, and a WD40 domain. The protein is present largely in the cytoplasm but also associates with the mitochondrial outer membrane. Mutations in this gene have been associated with Parkinson disease-8. [provided by RefSeq, Jul 2008]. |
Disorder MIM: | |
Disorder Html: | {Parkinson disease 8}, 607060 (3) |