TADA1 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	TADA1
Entrez Gene ID	117143
Full Name	transcriptional adaptor 1
Synonyms	ADA1,HFI1,STAF42,TADA1L,hADA1
General protein information	Preferred Names transcriptional adaptor 1 Names transcriptional adapter 1 SPT3-associated factor 42 (STAF42) transcriptional adapter 1-like protein transcriptional adaptor 1 (HFI1 homolog, yeast)
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 1 Map Location: 1q24.1
Summary	TADA1L is a protein subunit of the human STAGA complex (SPT3; (MIM 602947)/TAF9 (MIM 600822)/GCN5 (MIM 602301) acetyltransferase complex), which is a chromatin-modifying multiprotein complex (Martinez et al., 2001 [PubMed 11564863]).[supplied by OMIM, Apr 2009].
Disorder MIM:	612763

mRNA and Protein(s)

mRNA	Protein	Name
NM_053053.4	NP_444281.1	transcriptional adapter 1
NM_053053.3	NP_444281.1	transcriptional adapter 1

Pathways from BioSystems

Homologies

Pan troglodytes (chimpanzee)	TADA1	XP_513967.1
Bos taurus (cattle)	TADA1	NP_001094576.1
Rattus norvegicus (Norway rat)	Tada1	NP_001033069.2
Danio rerio (zebrafish)	tada1	NP_991169.1
	TADA1	XP_001087291.1
Mus musculus (house mouse)	Tada1	NP_084521.1
Gallus gallus (chicken)	TADA1L	NP_001183965.1
Xenopus tropicalis (tropical clawed frog)	tada1	NP_001005070.1
Homo sapiens (human)	TADA1	NP_444281.1
Drosophila melanogaster (fruit fly)	Ada1-2	NP_723703.1
Drosophila melanogaster (fruit fly)	Ada1-1	NP_723707.1
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP004085	XP_309635.4
Canis lupus familiaris (dog)	TADA1	XP_537213.2

Gene Ontology
Bibliography

Related articles in PubMed

Effect of ADA1 mother-fetus and wife-husband phenotypic differences on the ratio birth weight/placental weight in fertile women and on reproductive success in couples with RSA.
Gloria-Bottini F, Nicotra M, Amante A, Ambrosi S, Cozzoli E, Saccucci P, Bottini E, Magrini A
American journal of human biology : the official journal of the Human Biology Council24(2)177-82(2012 Mar-Apr)

Follow-up of a major linkage peak on chromosome 1 reveals suggestive QTLs associated with essential hypertension: GenNet study.
Ehret GB, O'Connor AA, Weder A, Cooper RS, Chakravarti A
European journal of human genetics : EJHG17(12)1650-7(2009 Dec)

Pre-B-cell leukemia homeobox 1 (PBX1) shows functional and possible genetic association with bone mineral density variation.
Cheung CL, Chan BY, Chan V, Ikegawa S, Kou I, Ngai H, Smith D, Luk KD, Huang QY, Mori S, Sham PC, Kung AW
Human molecular genetics18(4)679-87(2009 Feb)

Human STAGA complex is a chromatin-acetylating transcription coactivator that interacts with pre-mRNA splicing and DNA damage-binding factors in vivo.
Martinez E, Palhan VB, Tjernberg A, Lymar ES, Gamper AM, Kundu TK, Chait BT, Roeder RG
Molecular and cellular biology21(20)6782-95(2001 Oct)

A human SPT3-TAFII31-GCN5-L acetylase complex distinct from transcription factor IID.
Martinez E, Kundu TK, Fu J, Roeder RG
The Journal of biological chemistry273(37)23781-5(1998 Sep)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Differences between mother and fetus in ADA(1) phenotype may influence the ratio BW/PW in healthy women and reproductive success in RSA women.
Title: Effect of ADA1 mother-fetus and wife-husband phenotypic differences on the ratio birth weight/placental weight in fertile women and on reproductive success in couples with RSA.

Observational study of gene-disease association. (HuGE Navigator)
Title: Follow-up of a major linkage peak on chromosome 1 reveals suggestive QTLs associated with essential hypertension: GenNet study.

Observational study of gene-disease association. (HuGE Navigator)
Title: Pre-B-cell leukemia homeobox 1 (PBX1) shows functional and possible genetic association with bone mineral density variation.

The following TADA1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the TADA1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu13657	NM_053053.4 Latest version!	Homo sapiens transcriptional adaptor 1 (TADA1), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$139.50-$195.30 $279.00
View Old Accession Versions >>
OHu13657	NM_053053.3	Homo sapiens transcriptional adaptor 1 (TADA1), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$139.50-$195.30 $279.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

TADA1 ( NM_053053.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_444281.1 Homo sapiens transcriptional adaptor 1 (TADA1), mRNA.

Price & Availability↑

CloneID	OHu13657
Clone ID Related Accession (Same CDS sequence)	NM_053053.4 , NM_053053.3
Accession Version	NM_053053.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1008bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-09-26
Organism	Homo sapiens(human)
Product	transcriptional adapter 1
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from CN399642.1 and BC015401.2. On Nov 22, 2018 this sequence version replaced NM_053053.3. ##Evidence-Data-START## Transcript exon combination :: SRR3476690.1045213.1, SRR3476690.1132206.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000367874.5/ ENSP00000356848.4 RefSeq Select criteria :: based on single protein-coding transcript ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGGCGACCT TTGTGAGCGA GCTGGAGGCG GCCAAGAAGA ACTTAAGCGA GGCCCTGGGG 
GACAACGTGA AACAATACTG GGCTAACCTA AAGCTGTGGT TCAAGCAGAA GATCAGCAAA 
GAGGAGTTTG ACCTTGAAGC TCATAGACTT CTCACACAGG ATAATGTCCA TTCTCACAAT 
GATTTCCTCC TGGCCATTCT CACGCGTTGT CAGATTTTGG TTTCTACACC AGATGGTGCT 
GGATCTTTGC CTTGGCCAGG GGGTTCCGCA GCAAAACCTG GAAAACCCAA GGGAAAGAAA 
AAGCTTTCTT CTGTTCGTCA GAAATTTGAT CATAGATTCC AGCCTCAAAA TCCTCTCTCA 
GGAGCCCAGC AATTTGTGGC AAAGGATCCC CAAGATGATG ACGACTTGAA ACTTTGTTCC 
CACACAATGA TGCTTCCCAC TCGAGGCCAG CTTGAAGGGA GAATGATAGT GACTGCTTAT 
GAGCATGGGC TGGACAATGT CACCGAGGAG GCTGTTTCAG CTGTTGTCTA TGCTGTGGAG 
AATCACCTTA AAGATATACT GACGTCAGTT GTGTCAAGAA GGAAAGCTTA TCGGTTACGA 
GATGGTCATT TTAAATATGC CTTTGGCAGT AACGTGACCC CGCAGCCATA CCTGAAGAAT 
AGTGTAGTAG CTTACAACAA CTTAATAGAA AGCCCTCCAG CTTTTACTGC TCCCTGTGCT 
GGTCAGAATC CAGCTTCTCA CCCACCCCCT GATGATGCTG AGCAGCAGGC TGCACTCCTG 
CTGGCATGCT CCGGAGACAC TCTACCTGCA TCTTTGCCTC CGGTGAACAT GTACGATCTT 
TTTGAAGCTT TGCAGGTGCA CAGGGAAGTC ATCCCTACAC ATACTGTCTA TGCTCTTAAC 
ATTGAAAGGA TCATCACGAA ACTCTGGCAT CCAAATCATG AAGAGCTGCA GCAAGACAAA 
GTTCACCGCC AGCGCTTGGC AGCCAAGGAG GGGCTTTTGC TGTGCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_444281.1
CDS	32..1039
Translation	MATFVSELEAAKKNLSEALGDNVKQYWANLKLWFKQKISKEEFDLEAHRLLTQDNVHSHNDFLLAILTRCQILVSTPDGAGSLPWPGGSAAKPGKPKGKKKLSSVRQKFDHRFQPQNPLSGAQQFVAKDPQDDDDLKLCSHTMMLPTRGQLEGRMIVTAYEHGLDNVTEEAVSAVVYAVENHLKDILTSVVSRRKAYRLRDGHFKYAFGSNVTPQPYLKNSVVAYNNLIESPPAFTAPCAGQNPASHPPPDDAEQQAALLLACSGDTLPASLPPVNMYDLFEALQVHREVIPTHTVYALNIERIITKLWHPNHEELQQDKVHRQRLAAKEGLLLC

Target ORF information:

RefSeq Version	NM_053053.4
Organism	Homo sapiens(human)
Definition	Homo sapiens transcriptional adaptor 1 (TADA1), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_053053.4

ORF Insert Sequence:

ATGGCGACCT TTGTGAGCGA GCTGGAGGCG GCCAAGAAGA ACTTAAGCGA GGCCCTGGGG 
GACAACGTGA AACAATACTG GGCTAACCTA AAGCTGTGGT TCAAGCAGAA GATCAGCAAA 
GAGGAGTTTG ACCTTGAAGC TCATAGACTT CTCACACAGG ATAATGTCCA TTCTCACAAT 
GATTTCCTCC TGGCCATTCT CACGCGTTGT CAGATTTTGG TTTCTACACC AGATGGTGCT 
GGATCTTTGC CTTGGCCAGG GGGTTCCGCA GCAAAACCTG GAAAACCCAA GGGAAAGAAA 
AAGCTTTCTT CTGTTCGTCA GAAATTTGAT CATAGATTCC AGCCTCAAAA TCCTCTCTCA 
GGAGCCCAGC AATTTGTGGC AAAGGATCCC CAAGATGATG ACGACTTGAA ACTTTGTTCC 
CACACAATGA TGCTTCCCAC TCGAGGCCAG CTTGAAGGGA GAATGATAGT GACTGCTTAT 
GAGCATGGGC TGGACAATGT CACCGAGGAG GCTGTTTCAG CTGTTGTCTA TGCTGTGGAG 
AATCACCTTA AAGATATACT GACGTCAGTT GTGTCAAGAA GGAAAGCTTA TCGGTTACGA 
GATGGTCATT TTAAATATGC CTTTGGCAGT AACGTGACCC CGCAGCCATA CCTGAAGAAT 
AGTGTAGTAG CTTACAACAA CTTAATAGAA AGCCCTCCAG CTTTTACTGC TCCCTGTGCT 
GGTCAGAATC CAGCTTCTCA CCCACCCCCT GATGATGCTG AGCAGCAGGC TGCACTCCTG 
CTGGCATGCT CCGGAGACAC TCTACCTGCA TCTTTGCCTC CGGTGAACAT GTACGATCTT 
TTTGAAGCTT TGCAGGTGCA CAGGGAAGTC ATCCCTACAC ATACTGTCTA TGCTCTTAAC 
ATTGAAAGGA TCATCACGAA ACTCTGGCAT CCAAATCATG AAGAGCTGCA GCAAGACAAA 
GTTCACCGCC AGCGCTTGGC AGCCAAGGAG GGGCTTTTGC TGTGCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

TADA1 ( NM_053053.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_444281.1 Homo sapiens transcriptional adaptor 1 (TADA1), mRNA.

Price & Availability↑

CloneID	OHu13657
Clone ID Related Accession (Same CDS sequence)	NM_053053.4 , NM_053053.3
Accession Version	NM_053053.3	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1008bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-10-01
Organism	Homo sapiens(human)
Product	transcriptional adapter 1
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from CN399642.1 and BC015401.2. On Nov 1, 2008 this sequence version replaced NM_053053.2. ##Evidence-Data-START## Transcript exon combination :: BC015401.2, SRR1660807.135199.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGCGACCT TTGTGAGCGA GCTGGAGGCG GCCAAGAAGA ACTTAAGCGA GGCCCTGGGG 
GACAACGTGA AACAATACTG GGCTAACCTA AAGCTGTGGT TCAAGCAGAA GATCAGCAAA 
GAGGAGTTTG ACCTTGAAGC TCATAGACTT CTCACACAGG ATAATGTCCA TTCTCACAAT 
GATTTCCTCC TGGCCATTCT CACGCGTTGT CAGATTTTGG TTTCTACACC AGATGGTGCT 
GGATCTTTGC CTTGGCCAGG GGGTTCCGCA GCAAAACCTG GAAAACCCAA GGGAAAGAAA 
AAGCTTTCTT CTGTTCGTCA GAAATTTGAT CATAGATTCC AGCCTCAAAA TCCTCTCTCA 
GGAGCCCAGC AATTTGTGGC AAAGGATCCC CAAGATGATG ACGACTTGAA ACTTTGTTCC 
CACACAATGA TGCTTCCCAC TCGAGGCCAG CTTGAAGGGA GAATGATAGT GACTGCTTAT 
GAGCATGGGC TGGACAATGT CACCGAGGAG GCTGTTTCAG CTGTTGTCTA TGCTGTGGAG 
AATCACCTTA AAGATATACT GACGTCAGTT GTGTCAAGAA GGAAAGCTTA TCGGTTACGA 
GATGGTCATT TTAAATATGC CTTTGGCAGT AACGTGACCC CGCAGCCATA CCTGAAGAAT 
AGTGTAGTAG CTTACAACAA CTTAATAGAA AGCCCTCCAG CTTTTACTGC TCCCTGTGCT 
GGTCAGAATC CAGCTTCTCA CCCACCCCCT GATGATGCTG AGCAGCAGGC TGCACTCCTG 
CTGGCATGCT CCGGAGACAC TCTACCTGCA TCTTTGCCTC CGGTGAACAT GTACGATCTT 
TTTGAAGCTT TGCAGGTGCA CAGGGAAGTC ATCCCTACAC ATACTGTCTA TGCTCTTAAC 
ATTGAAAGGA TCATCACGAA ACTCTGGCAT CCAAATCATG AAGAGCTGCA GCAAGACAAA 
GTTCACCGCC AGCGCTTGGC AGCCAAGGAG GGGCTTTTGC TGTGCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_444281.1
CDS	185..1192
Translation	MATFVSELEAAKKNLSEALGDNVKQYWANLKLWFKQKISKEEFDLEAHRLLTQDNVHSHNDFLLAILTRCQILVSTPDGAGSLPWPGGSAAKPGKPKGKKKLSSVRQKFDHRFQPQNPLSGAQQFVAKDPQDDDDLKLCSHTMMLPTRGQLEGRMIVTAYEHGLDNVTEEAVSAVVYAVENHLKDILTSVVSRRKAYRLRDGHFKYAFGSNVTPQPYLKNSVVAYNNLIESPPAFTAPCAGQNPASHPPPDDAEQQAALLLACSGDTLPASLPPVNMYDLFEALQVHREVIPTHTVYALNIERIITKLWHPNHEELQQDKVHRQRLAAKEGLLLC

Target ORF information:

RefSeq Version	NM_053053.3
Organism	Homo sapiens(human)
Definition	Homo sapiens transcriptional adaptor 1 (TADA1), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_053053.3

ORF Insert Sequence:

ATGGCGACCT TTGTGAGCGA GCTGGAGGCG GCCAAGAAGA ACTTAAGCGA GGCCCTGGGG 
GACAACGTGA AACAATACTG GGCTAACCTA AAGCTGTGGT TCAAGCAGAA GATCAGCAAA 
GAGGAGTTTG ACCTTGAAGC TCATAGACTT CTCACACAGG ATAATGTCCA TTCTCACAAT 
GATTTCCTCC TGGCCATTCT CACGCGTTGT CAGATTTTGG TTTCTACACC AGATGGTGCT 
GGATCTTTGC CTTGGCCAGG GGGTTCCGCA GCAAAACCTG GAAAACCCAA GGGAAAGAAA 
AAGCTTTCTT CTGTTCGTCA GAAATTTGAT CATAGATTCC AGCCTCAAAA TCCTCTCTCA 
GGAGCCCAGC AATTTGTGGC AAAGGATCCC CAAGATGATG ACGACTTGAA ACTTTGTTCC 
CACACAATGA TGCTTCCCAC TCGAGGCCAG CTTGAAGGGA GAATGATAGT GACTGCTTAT 
GAGCATGGGC TGGACAATGT CACCGAGGAG GCTGTTTCAG CTGTTGTCTA TGCTGTGGAG 
AATCACCTTA AAGATATACT GACGTCAGTT GTGTCAAGAA GGAAAGCTTA TCGGTTACGA 
GATGGTCATT TTAAATATGC CTTTGGCAGT AACGTGACCC CGCAGCCATA CCTGAAGAAT 
AGTGTAGTAG CTTACAACAA CTTAATAGAA AGCCCTCCAG CTTTTACTGC TCCCTGTGCT 
GGTCAGAATC CAGCTTCTCA CCCACCCCCT GATGATGCTG AGCAGCAGGC TGCACTCCTG 
CTGGCATGCT CCGGAGACAC TCTACCTGCA TCTTTGCCTC CGGTGAACAT GTACGATCTT 
TTTGAAGCTT TGCAGGTGCA CAGGGAAGTC ATCCCTACAC ATACTGTCTA TGCTCTTAAC 
ATTGAAAGGA TCATCACGAA ACTCTGGCAT CCAAATCATG AAGAGCTGCA GCAAGACAAA 
GTTCACCGCC AGCGCTTGGC AGCCAAGGAG GGGCTTTTGC TGTGCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Effect of ADA1 mother-fetus and wife-husband phenotypic differences on the ratio birth weight/placental weight in fertile women and on reproductive success in couples with RSA.
American journal of human biology : the official journal of the Human Biology Council24(2)177-82(2012 Mar-Apr)
Gloria-Bottini F,Nicotra M,Amante A,Ambrosi S,Cozzoli E,Saccucci P,Bottini E,Magrini A

Follow-up of a major linkage peak on chromosome 1 reveals suggestive QTLs associated with essential hypertension: GenNet study.
European journal of human genetics : EJHG17(12)1650-7(2009 Dec)
Ehret GB,O'Connor AA,Weder A,Cooper RS,Chakravarti A

Pre-B-cell leukemia homeobox 1 (PBX1) shows functional and possible genetic association with bone mineral density variation.
Human molecular genetics18(4)679-87(2009 Feb)
Cheung CL,Chan BY,Chan V,Ikegawa S,Kou I,Ngai H,Smith D,Luk KD,Huang QY,Mori S,Sham PC,Kung AW

Human STAGA complex is a chromatin-acetylating transcription coactivator that interacts with pre-mRNA splicing and DNA damage-binding factors in vivo.
Molecular and cellular biology21(20)6782-95(2001 Oct)
Martinez E,Palhan VB,Tjernberg A,Lymar ES,Gamper AM,Kundu TK,Chait BT,Roeder RG

A human SPT3-TAFII31-GCN5-L acetylase complex distinct from transcription factor IID.
The Journal of biological chemistry273(37)23781-5(1998 Sep)
Martinez E,Kundu TK,Fu J,Roeder RG

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TADA1 cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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