Gene Symbol | AGAP3 |
Entrez Gene ID | 116988 |
Full Name | ArfGAP with GTPase domain, ankyrin repeat and PH domain 3 |
Synonyms | AGAP-3,CENTG3,CRAG,MRIP-1,cnt-g3 |
General protein information |
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Gene Type | protein-coding |
Organism | Homo sapiens(human) |
Genome | |
Summary | This gene encodes an essential component of the N-methyl-D-aspartate (NMDA) receptor signaling complex which mediates long-term potentiation in synapses by linking activation of NMDA receptor to alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptor trafficking. The encoded protein contains an N-terminal GTPase-like domain, a pleckstrin homology domain, an ArfGAP domain and several C-terminal ankryn repeat domains. [provided by RefSeq, Apr 2017]. |
Disorder MIM: |