GRIN3B cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	GRIN3B
Entrez Gene ID	116444
Full Name	glutamate ionotropic receptor NMDA type subunit 3B
Synonyms	GluN3B,NR3B
General protein information	Preferred Names glutamate ionotropic receptor NMDA type subunit 3B Names glutamate receptor ionotropic, NMDA 3B N-methyl-D-aspartate receptor subtype 3B NMDA receptor subunit 3B NMDA type glutamate receptor subunit NR3B NMDAR3B glutamate [NMDA] receptor subunit 3B glutamate receptor, ionotropic, N-methyl-D-aspartate 3B
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 19 Map Location: 19p13.3
Summary	The protein encoded by this gene is a subunit of an N-methyl-D-aspartate (NMDA) receptor. The encoded protein is found primarily in motor neurons, where it forms a heterotetramer with GRIN1 to create an excitatory glycine receptor. Variations in this gene have been proposed to be linked to schizophrenia. [provided by RefSeq, Nov 2015].
Disorder MIM:	606651

mRNA and Protein(s)

mRNA	Protein	Name
XM_017026243.1	XP_016881732.1	glutamate receptor ionotropic, NMDA 3B isoform X1
NM_138690.2	NP_619635.1	glutamate receptor ionotropic, NMDA 3B precursor
NM_138690.3	NP_619635.1	glutamate receptor ionotropic, NMDA 3B precursor
XM_017026243.2	XP_016881732.1	glutamate receptor ionotropic, NMDA 3B isoform X1

Pathways from BioSystems

Homologies

Homo sapiens (human)	GRIN3B	NP_619635.1
Rattus norvegicus (Norway rat)	Grin3b	NP_579842.2
Danio rerio (zebrafish)	LOC566411	XP_694772.5
Danio rerio (zebrafish)	LOC100333101	XP_002663775.3
Bos taurus (cattle)	GRIN3B	XP_002689214.2
Mus musculus (house mouse)	Grin3b	NP_569722.1
Gallus gallus (chicken)	GRIN3B	XP_426726.4
Danio rerio (zebrafish)	LOC571394	XP_700069.6
Canis lupus familiaris (dog)	GRIN3B	XP_542210.3
Xenopus tropicalis (tropical clawed frog)	grin3b	XP_002937428.1

Gene Ontology
Bibliography

Related articles in PubMed

GRIN3B missense mutation as an inherited risk factor for schizophrenia: whole-exome sequencing in a family with a familiar history of psychotic disorders.
Hornig T, Gr?ning B, Kundu K, Houwaart T, Backofen R, Biber K, Normann C
Genetics research99e1(2017 01)

Novel and rare functional genomic variants in multiple autoimmune syndrome and Sj?gren's syndrome.
Johar AS, Mastronardi C, Rojas-Villarraga A, Patel HR, Chuah A, Peng K, Higgins A, Milburn P, Palmer S, Silva-Lara MF, Velez JI, Andrews D, Field M, Huttley G, Goodnow C, Anaya JM, Arcos-Burgos M
Journal of translational medicine13173(2015 Jun)

A naturally occurring null variant of the NMDA type glutamate receptor NR3B subunit is a risk factor of schizophrenia.
Matsuno H, Ohi K, Hashimoto R, Yamamori H, Yasuda Y, Fujimoto M, Yano-Umeda S, Saneyoshi T, Takeda M, Hayashi Y
PloS one10(3)e0116319(2015)

A recently-discovered NMDA receptor gene, GRIN3B, is associated with duration mismatch negativity.
Lin YT, Hsieh MH, Liu CC, Hwang TJ, Chien YL, Hwu HG, Liu CM
Psychiatry research218(3)356-8(2014 Aug)

Variants in the ATP-binding cassette transporter (ABCA7), apolipoprotein E ?4,and the risk of late-onset Alzheimer disease in African Americans.
Reitz C, Jun G, Naj A, Rajbhandary R, Vardarajan BN, Wang LS, Valladares O, Lin CF, Larson EB, Graff-Radford NR, Evans D, De Jager PL, Crane PK, Buxbaum JD, Murrell JR, Raj T, Ertekin-Taner N, Logue M, Baldwin CT, Green RC, Barnes LL, Cantwell LB, Fallin MD, Go RC, Griffith P, Obisesan TO, Manly JJ, Lunetta KL, Kamboh MI, Lopez OL, Bennett DA, Hendrie H, Hall KS, Goate AM, Byrd GS, Kukull WA, Foroud TM, Haines JL, Farrer LA, Pericak-Vance MA, Schellenberg GD, Mayeux R,
JAMA309(14)1483-92(2013 Apr)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

GRIN3B missense mutation is an inherited risk factor for schizophrenia.
Title: GRIN3B missense mutation as an inherited risk factor for schizophrenia: whole-exome sequencing in a family with a familiar history of psychotic disorders.

Authors investigated the significance of a common human genetic variation of the NMDAR NR3B subunit
Title: A naturally occurring null variant of the NMDA type glutamate receptor NR3B subunit is a risk factor of schizophrenia.

Rs2240158 of GRIN3B was significantly associated with mismatch negativity in healthy subjects.
Title: A recently-discovered NMDA receptor gene, GRIN3B, is associated with duration mismatch negativity.

Observational study of gene-disease association. (HuGE Navigator)
Title: Comprehensive copy number variant (CNV) analysis of neuronal pathways genes in psychiatric disorders identifies rare variants within patients.

our findings suggest that the over-expression of NR3B subunit of NMDA receptor is a long lasting result of chronic opioid abuse.
Title: Expression of NR3B but not NR2D subunit of NMDA receptor in human blood lymphocytes can serve as a suitable peripheral marker for opioid addiction studies.

The following GRIN3B gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the GRIN3B cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu29413	NM_138690.3 Latest version!	Homo sapiens glutamate ionotropic receptor NMDA type subunit 3B (GRIN3B), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$399.50-$559.30 $799.00
OHu88181	XM_017026243.2 Latest version!	Homo sapiens glutamate ionotropic receptor NMDA type subunit 3B (GRIN3B), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$307.30 $439.00
View Old Accession Versions >>
OHu29413	NM_138690.2	Homo sapiens glutamate ionotropic receptor NMDA type subunit 3B (GRIN3B), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$399.50-$559.30 $799.00
OHu88181	XM_017026243.1	Homo sapiens glutamate ionotropic receptor NMDA type subunit 3B (GRIN3B), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$307.30 $439.00
Hide Old Accession Versions >>

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***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

GRIN3B ( NM_138690.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_619635.1 Homo sapiens glutamate ionotropic receptor NMDA type subunit 3B (GRIN3B), mRNA.

Price & Availability↑

CloneID	OHu29413
Clone ID Related Accession (Same CDS sequence)	NM_138690.2 , NM_138690.3
Accession Version	NM_138690.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 3132bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-02-24
Organism	Homo sapiens(human)
Product	glutamate receptor ionotropic, NMDA 3B precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AY507106.1, BK004079.1 and BM977634.1. On Nov 14, 2015 this sequence version replaced NM_138690.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AY507106.1, BK004079.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2158569, SAMN01820689 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGAGTTTG TGCGGGCGCT GTGGCTGGGC CTGGCGCTGG CGCTGGGGCC GGGGTCCGCG 
GGGGGCCACC CTCAGCCGTG CGGCGTCCTG GCGCGCCTCG GGGGCTCCGT GCGCCTGGGC 
GCCCTCCTGC CCCGCGCGCC TCTCGCCCGC GCCCGCGCCC GCGCCGCCCT GGCCCGGGCC 
GCCCTGGCGC CGCGGCTGCC GCACAACCTG AGCTTGGAGC TGGTGGTCGC CGCGCCCCCC 
GCCCGCGACC CCGCCTCGCT GACCCGCGGC CTGTGCCAGG CGCTGGTGCC TCCGGGCGTG 
GCGGCCCTGC TCGCCTTTCC CGAGGCTCGG CCCGAGCTGC TGCAGCTGCA CTTCCTGGCG 
GCGGCCACCG AGACCCCCGT GCTCAGCCTG CTGCGGCGGG AGGCGCGCGC GCCCCTCGGA 
GCCCCGAACC CATTCCACCT GCAGCTGCAC TGGGCCAGCC CCCTGGAGAC GCTGCTGGAT 
GTGCTGGTGG CGGTGCTGCA GGCGCACGCC TGGGAAGACG TCGGCCTGGC CCTGTGCCGC 
ACTCAGGACC CCGGCGGCCT GGTGGCCCTC TGGACAAGCC GGGCTGGCCG GCCCCCACAG 
CTGGTCCTGG ACCTAAGCCG GCGGGACACG GGAGATGCAG GACTGCGGGC ACGCCTGGCC 
CCGATGGCGG CGCCAGTGGG GGGTGAAGCA CCGGTACCCG CGGCGGTCCT CCTCGGCTGT 
GACATCGCCC GTGCCCGTCG GGTGCTGGAG GCCGTACCTC CCGGCCCCCA CTGGCTGTTG 
GGGACACCAC TGCCGCCCAA GGCCCTGCCC ACCGCGGGGC TGCCACCAGG GCTGCTGGCG 
CTGGGCGAGG TGGCACGACC CCCGCTGGAG GCCGCCATCC ATGACATTGT GCAACTGGTG 
GCCCGGGCGC TGGGCAGTGC GGCCCAGGTG CAGCCGAAGC GAGCCCTCCT CCCCGCCCCG 
GTCAACTGCG GGGACCTGCA GCCGGCCGGG CCCGAGTCCC CGGGGCGCTT CTTGGCACGG 
TTCCTGGCCA ACACGTCCTT CCAGGGCCGC ACGGGCCCCG TGTGGGTGAC AGGCAGCTCC 
CAGGTACACA TGTCTCGGCA CTTTAAGGTG TGGAGCCTTC GCCGGGACCC ACGGGGCGCC 
CCGGCCTGGG CCACGGTGGG CAGCTGGCGG GACGGCCAGC TGGACTTGGA ACCGGGAGGT 
GCCTCTGCAC GGCCCCCGCC CCCACAGGGT GCCCAGGTCT GGCCCAAGCT GCGTGTGGTA 
ACGCTGTTGG AACACCCATT TGTGTTTGCC CGTGATCCAG ACGAAGACGG GCAGTGCCCA 
GCGGGGCAGC TGTGCCTGGA CCCTGGCACC AACGACTCGG CCACCCTGGA CGCACTGTTC 
GCCGCGCTGG CCAACGGCTC AGCGCCCCGT GCCCTGCGCA AGTGCTGCTA CGGCTACTGC 
ATTGACCTGC TGGAGCGGCT GGCGGAGGAC ACGCCCTTCG ACTTCGAGCT GTACCTCGTG 
GGTGACGGCA AGTACGGCGC CCTGCGGGAC GGCCGCTGGA CCGGCCTGGT CGGGGACCTG 
CTGGCCGGCC GGGCCCACAT GGCGGTCACC AGCTTCAGTA TCAACTCCGC CCGCTCACAG 
GTGGTGGACT TCACCAGCCC CTTCTTCTCC ACCAGCCTGG GCATCATGGT GCGGGCACGG 
GACACGGCCT CACCCATCGG TGCCTTTATG TGGCCCCTGC ACTGGTCCAC GTGGCTGGGC 
GTCTTTGCGG CCCTGCACCT CACCGCGCTC TTCCTCACCG TGTACGAGTG GCGTAGCCCC 
TACGGCCTCA CGCCACGTGG CCGCAACCGC AGCACCGTCT TCTCCTACTC CTCAGCCCTC 
AACCTGTGCT ACGCCATCCT CTTCAGACGC ACCGTGTCCA GCAAGACGCC CAAGTGCCCC 
ACGGGCCGCC TGCTCATGAA CCTCTGGGCC ATCTTCTGCC TGCTGGTGCT GTCCAGCTAC 
ACGGCCAACC TGGCTGCCGT CATGGTCGGG GACAAGACCT TCGAGGAGCT GTCGGGGATC 
CACGACCCCA AGCTGCACCA CCCGGCGCAG GGCTTCCGCT TCGGCACCGT GTGGGAGAGC 
AGCGCCGAGG CGTACATCAA GAAGAGCTTC CCCGACATGC ACGCACACAT GCGGCGCCAC 
AGCGCGCCCA CCACGCCCCG CGGCGTCGCC ATGCTCACGA GCGACCCCCC CAAGCTCAAC 
GCCTTCATCA TGGACAAGTC GCTCCTGGAC TACGAGGTCT CCATCGACGC CGACTGCAAA 
CTGCTGACCG TGGGAAAGCC CTTCGCCATT GAGGGCTATG GGATCGGACT GCCCCAGAAC 
TCGCCGCTCA CCTCCAACCT GTCCGAGTTC ATCAGCCGCT ACAAGTCCTC CGGCTTCATC 
GACCTGCTCC ACGACAAGTG GTACAAGATG GTGCCTTGCG GCAAGCGGGT CTTTGCGGTT 
ACAGAGACCC TGCAGATGAG CATCTACCAC TTCGCGGGCC TCTTCGTGTT GCTGTGCCTG 
GGCCTGGGCA GCGCTCTGCT CAGCTCGCTG GGCGAGCACG CCTTCTTCCG CCTGGCGCTG 
CCGCGCATCC GCAAGGGGAG CAGGCTGCAG TACTGGCTGC ACACCAGCCA GAAAATCCAC 
CGCGCCCTCA ACACGGAGCC ACCAGAGGGG TCGAAGGAGG AGACGGCAGA GGCGGAGCCC 
AGCGGCCCCG AGGTGGAGCA GCAGCAGCAG CAGCAGGACC AGCCAACGGC TCCGGAGGGC 
TGGAAACGGG CGCGCCGGGC CGTGGACAAG GAGCGCCGCG TGCGCTTCCT GCTGGAGCCC 
GCCGTGGTTG TGGCACCCGA AGCGGACGCG GAGGCGGAGG CTGCGCCGCG AGAGGGCCCC 
GTCTGGCTGT GCTCCTACGG CCGCCCGCCC GCCGCAAGGC CCACGGGGGC CCCCCAGCCC 
GGGGAGCTGC AGGAGCTGGA GCGCCGCATC GAAGTCGCGC GTGAGCGGCT CCGCCAGGCC 
CTGGTGCGGC GCGGCCAGCT CCTGGCACAG CTCGGGGACA GCGCACGTCA CCGGCCTCGG 
CGCTTGCTTC AGGCCAGAGC GGCCCCCGCG GAGGCCCCAC CACACTCTGG CCGACCGGGG 
AGCCAGGAAT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_619635.1
CDS	20..3151
Translation	MEFVRALWLGLALALGPGSAGGHPQPCGVLARLGGSVRLGALLPRAPLARARARAALARAALAPRLPHNLSLELVVAAPPARDPASLTRGLCQALVPPGVAALLAFPEARPELLQLHFLAAATETPVLSLLRREARAPLGAPNPFHLQLHWASPLETLLDVLVAVLQAHAWEDVGLALCRTQDPGGLVALWTSRAGRPPQLVLDLSRRDTGDAGLRARLAPMAAPVGGEAPVPAAVLLGCDIARARRVLEAVPPGPHWLLGTPLPPKALPTAGLPPGLLALGEVARPPLEAAIHDIVQLVARALGSAAQVQPKRALLPAPVNCGDLQPAGPESPGRFLARFLANTSFQGRTGPVWVTGSSQVHMSRHFKVWSLRRDPRGAPAWATVGSWRDGQLDLEPGGASARPPPPQGAQVWPKLRVVTLLEHPFVFARDPDEDGQCPAGQLCLDPGTNDSATLDALFAALANGSAPRALRKCCYGYCIDLLERLAEDTPFDFELYLVGDGKYGALRDGRWTGLVGDLLAGRAHMAVTSFSINSARSQVVDFTSPFFSTSLGIMVRARDTASPIGAFMWPLHWSTWLGVFAALHLTALFLTVYEWRSPYGLTPRGRNRSTVFSYSSALNLCYAILFRRTVSSKTPKCPTGRLLMNLWAIFCLLVLSSYTANLAAVMVGDKTFEELSGIHDPKLHHPAQGFRFGTVWESSAEAYIKKSFPDMHAHMRRHSAPTTPRGVAMLTSDPPKLNAFIMDKSLLDYEVSIDADCKLLTVGKPFAIEGYGIGLPQNSPLTSNLSEFISRYKSSGFIDLLHDKWYKMVPCGKRVFAVTETLQMSIYHFAGLFVLLCLGLGSALLSSLGEHAFFRLALPRIRKGSRLQYWLHTSQKIHRALNTEPPEGSKEETAEAEPSGPEVEQQQQQQDQPTAPEGWKRARRAVDKERRVRFLLEPAVVVAPEADAEAEAAPREGPVWLCSYGRPPAARPTGAPQPGELQELERRIEVARERLRQALVRRGQLLAQLGDSARHRPRRLLQARAAPAEAPPHSGRPGSQE

Target ORF information:

RefSeq Version	NM_138690.2
Organism	Homo sapiens(human)
Definition	Homo sapiens glutamate ionotropic receptor NMDA type subunit 3B (GRIN3B), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_138690.2

ORF Insert Sequence:

ATGGAGTTTG TGCGGGCGCT GTGGCTGGGC CTGGCGCTGG CGCTGGGGCC GGGGTCCGCG 
GGGGGCCACC CTCAGCCGTG CGGCGTCCTG GCGCGCCTCG GGGGCTCCGT GCGCCTGGGC 
GCCCTCCTGC CCCGCGCGCC TCTCGCCCGC GCCCGCGCCC GCGCCGCCCT GGCCCGGGCC 
GCCCTGGCGC CGCGGCTGCC GCACAACCTG AGCTTGGAGC TGGTGGTCGC CGCGCCCCCC 
GCCCGCGACC CCGCCTCGCT GACCCGCGGC CTGTGCCAGG CGCTGGTGCC TCCGGGCGTG 
GCGGCCCTGC TCGCCTTTCC CGAGGCTCGG CCCGAGCTGC TGCAGCTGCA CTTCCTGGCG 
GCGGCCACCG AGACCCCCGT GCTCAGCCTG CTGCGGCGGG AGGCGCGCGC GCCCCTCGGA 
GCCCCGAACC CATTCCACCT GCAGCTGCAC TGGGCCAGCC CCCTGGAGAC GCTGCTGGAT 
GTGCTGGTGG CGGTGCTGCA GGCGCACGCC TGGGAAGACG TCGGCCTGGC CCTGTGCCGC 
ACTCAGGACC CCGGCGGCCT GGTGGCCCTC TGGACAAGCC GGGCTGGCCG GCCCCCACAG 
CTGGTCCTGG ACCTAAGCCG GCGGGACACG GGAGATGCAG GACTGCGGGC ACGCCTGGCC 
CCGATGGCGG CGCCAGTGGG GGGTGAAGCA CCGGTACCCG CGGCGGTCCT CCTCGGCTGT 
GACATCGCCC GTGCCCGTCG GGTGCTGGAG GCCGTACCTC CCGGCCCCCA CTGGCTGTTG 
GGGACACCAC TGCCGCCCAA GGCCCTGCCC ACCGCGGGGC TGCCACCAGG GCTGCTGGCG 
CTGGGCGAGG TGGCACGACC CCCGCTGGAG GCCGCCATCC ATGACATTGT GCAACTGGTG 
GCCCGGGCGC TGGGCAGTGC GGCCCAGGTG CAGCCGAAGC GAGCCCTCCT CCCCGCCCCG 
GTCAACTGCG GGGACCTGCA GCCGGCCGGG CCCGAGTCCC CGGGGCGCTT CTTGGCACGG 
TTCCTGGCCA ACACGTCCTT CCAGGGCCGC ACGGGCCCCG TGTGGGTGAC AGGCAGCTCC 
CAGGTACACA TGTCTCGGCA CTTTAAGGTG TGGAGCCTTC GCCGGGACCC ACGGGGCGCC 
CCGGCCTGGG CCACGGTGGG CAGCTGGCGG GACGGCCAGC TGGACTTGGA ACCGGGAGGT 
GCCTCTGCAC GGCCCCCGCC CCCACAGGGT GCCCAGGTCT GGCCCAAGCT GCGTGTGGTA 
ACGCTGTTGG AACACCCATT TGTGTTTGCC CGTGATCCAG ACGAAGACGG GCAGTGCCCA 
GCGGGGCAGC TGTGCCTGGA CCCTGGCACC AACGACTCGG CCACCCTGGA CGCACTGTTC 
GCCGCGCTGG CCAACGGCTC AGCGCCCCGT GCCCTGCGCA AGTGCTGCTA CGGCTACTGC 
ATTGACCTGC TGGAGCGGCT GGCGGAGGAC ACGCCCTTCG ACTTCGAGCT GTACCTCGTG 
GGTGACGGCA AGTACGGCGC CCTGCGGGAC GGCCGCTGGA CCGGCCTGGT CGGGGACCTG 
CTGGCCGGCC GGGCCCACAT GGCGGTCACC AGCTTCAGTA TCAACTCCGC CCGCTCACAG 
GTGGTGGACT TCACCAGCCC CTTCTTCTCC ACCAGCCTGG GCATCATGGT GCGGGCACGG 
GACACGGCCT CACCCATCGG TGCCTTTATG TGGCCCCTGC ACTGGTCCAC GTGGCTGGGC 
GTCTTTGCGG CCCTGCACCT CACCGCGCTC TTCCTCACCG TGTACGAGTG GCGTAGCCCC 
TACGGCCTCA CGCCACGTGG CCGCAACCGC AGCACCGTCT TCTCCTACTC CTCAGCCCTC 
AACCTGTGCT ACGCCATCCT CTTCAGACGC ACCGTGTCCA GCAAGACGCC CAAGTGCCCC 
ACGGGCCGCC TGCTCATGAA CCTCTGGGCC ATCTTCTGCC TGCTGGTGCT GTCCAGCTAC 
ACGGCCAACC TGGCTGCCGT CATGGTCGGG GACAAGACCT TCGAGGAGCT GTCGGGGATC 
CACGACCCCA AGCTGCACCA CCCGGCGCAG GGCTTCCGCT TCGGCACCGT GTGGGAGAGC 
AGCGCCGAGG CGTACATCAA GAAGAGCTTC CCCGACATGC ACGCACACAT GCGGCGCCAC 
AGCGCGCCCA CCACGCCCCG CGGCGTCGCC ATGCTCACGA GCGACCCCCC CAAGCTCAAC 
GCCTTCATCA TGGACAAGTC GCTCCTGGAC TACGAGGTCT CCATCGACGC CGACTGCAAA 
CTGCTGACCG TGGGAAAGCC CTTCGCCATT GAGGGCTATG GGATCGGACT GCCCCAGAAC 
TCGCCGCTCA CCTCCAACCT GTCCGAGTTC ATCAGCCGCT ACAAGTCCTC CGGCTTCATC 
GACCTGCTCC ACGACAAGTG GTACAAGATG GTGCCTTGCG GCAAGCGGGT CTTTGCGGTT 
ACAGAGACCC TGCAGATGAG CATCTACCAC TTCGCGGGCC TCTTCGTGTT GCTGTGCCTG 
GGCCTGGGCA GCGCTCTGCT CAGCTCGCTG GGCGAGCACG CCTTCTTCCG CCTGGCGCTG 
CCGCGCATCC GCAAGGGGAG CAGGCTGCAG TACTGGCTGC ACACCAGCCA GAAAATCCAC 
CGCGCCCTCA ACACGGAGCC ACCAGAGGGG TCGAAGGAGG AGACGGCAGA GGCGGAGCCC 
AGCGGCCCCG AGGTGGAGCA GCAGCAGCAG CAGCAGGACC AGCCAACGGC TCCGGAGGGC 
TGGAAACGGG CGCGCCGGGC CGTGGACAAG GAGCGCCGCG TGCGCTTCCT GCTGGAGCCC 
GCCGTGGTTG TGGCACCCGA AGCGGACGCG GAGGCGGAGG CTGCGCCGCG AGAGGGCCCC 
GTCTGGCTGT GCTCCTACGG CCGCCCGCCC GCCGCAAGGC CCACGGGGGC CCCCCAGCCC 
GGGGAGCTGC AGGAGCTGGA GCGCCGCATC GAAGTCGCGC GTGAGCGGCT CCGCCAGGCC 
CTGGTGCGGC GCGGCCAGCT CCTGGCACAG CTCGGGGACA GCGCACGTCA CCGGCCTCGG 
CGCTTGCTTC AGGCCAGAGC GGCCCCCGCG GAGGCCCCAC CACACTCTGG CCGACCGGGG 
AGCCAGGAAT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

GRIN3B ( NM_138690.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_619635.1 Homo sapiens glutamate ionotropic receptor NMDA type subunit 3B (GRIN3B), mRNA.

Price & Availability↑

CloneID	OHu29413
Clone ID Related Accession (Same CDS sequence)	NM_138690.2 , NM_138690.3
Accession Version	NM_138690.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 3132bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-06-29
Organism	Homo sapiens(human)
Product	glutamate receptor ionotropic, NMDA 3B precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AY507106.1, BK004079.1 and BM977634.1. On May 17, 2019 this sequence version replaced NM_138690.2. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AY507106.1, AY507107.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2158569, SAMN01820689 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000234389.3/ ENSP00000234389.3 RefSeq Select criteria :: based on conservation, expression, longest protein ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGGAGTTTG TGCGGGCGCT GTGGCTGGGC CTGGCGCTGG CGCTGGGGCC GGGGTCCGCG 
GGGGGCCACC CTCAGCCGTG CGGCGTCCTG GCGCGCCTCG GGGGCTCCGT GCGCCTGGGC 
GCCCTCCTGC CCCGCGCGCC TCTCGCCCGC GCCCGCGCCC GCGCCGCCCT GGCCCGGGCC 
GCCCTGGCGC CGCGGCTGCC GCACAACCTG AGCTTGGAGC TGGTGGTCGC CGCGCCCCCC 
GCCCGCGACC CCGCCTCGCT GACCCGCGGC CTGTGCCAGG CGCTGGTGCC TCCGGGCGTG 
GCGGCCCTGC TCGCCTTTCC CGAGGCTCGG CCCGAGCTGC TGCAGCTGCA CTTCCTGGCG 
GCGGCCACCG AGACCCCCGT GCTCAGCCTG CTGCGGCGGG AGGCGCGCGC GCCCCTCGGA 
GCCCCGAACC CATTCCACCT GCAGCTGCAC TGGGCCAGCC CCCTGGAGAC GCTGCTGGAT 
GTGCTGGTGG CGGTGCTGCA GGCGCACGCC TGGGAAGACG TCGGCCTGGC CCTGTGCCGC 
ACTCAGGACC CCGGCGGCCT GGTGGCCCTC TGGACAAGCC GGGCTGGCCG GCCCCCACAG 
CTGGTCCTGG ACCTAAGCCG GCGGGACACG GGAGATGCAG GACTGCGGGC ACGCCTGGCC 
CCGATGGCGG CGCCAGTGGG GGGTGAAGCA CCGGTACCCG CGGCGGTCCT CCTCGGCTGT 
GACATCGCCC GTGCCCGTCG GGTGCTGGAG GCCGTACCTC CCGGCCCCCA CTGGCTGTTG 
GGGACACCAC TGCCGCCCAA GGCCCTGCCC ACCGCGGGGC TGCCACCAGG GCTGCTGGCG 
CTGGGCGAGG TGGCACGACC CCCGCTGGAG GCCGCCATCC ATGACATTGT GCAACTGGTG 
GCCCGGGCGC TGGGCAGTGC GGCCCAGGTG CAGCCGAAGC GAGCCCTCCT CCCCGCCCCG 
GTCAACTGCG GGGACCTGCA GCCGGCCGGG CCCGAGTCCC CGGGGCGCTT CTTGGCACGG 
TTCCTGGCCA ACACGTCCTT CCAGGGCCGC ACGGGCCCCG TGTGGGTGAC AGGCAGCTCC 
CAGGTACACA TGTCTCGGCA CTTTAAGGTG TGGAGCCTTC GCCGGGACCC ACGGGGCGCC 
CCGGCCTGGG CCACGGTGGG CAGCTGGCGG GACGGCCAGC TGGACTTGGA ACCGGGAGGT 
GCCTCTGCAC GGCCCCCGCC CCCACAGGGT GCCCAGGTCT GGCCCAAGCT GCGTGTGGTA 
ACGCTGTTGG AACACCCATT TGTGTTTGCC CGTGATCCAG ACGAAGACGG GCAGTGCCCA 
GCGGGGCAGC TGTGCCTGGA CCCTGGCACC AACGACTCGG CCACCCTGGA CGCACTGTTC 
GCCGCGCTGG CCAACGGCTC AGCGCCCCGT GCCCTGCGCA AGTGCTGCTA CGGCTACTGC 
ATTGACCTGC TGGAGCGGCT GGCGGAGGAC ACGCCCTTCG ACTTCGAGCT GTACCTCGTG 
GGTGACGGCA AGTACGGCGC CCTGCGGGAC GGCCGCTGGA CCGGCCTGGT CGGGGACCTG 
CTGGCCGGCC GGGCCCACAT GGCGGTCACC AGCTTCAGTA TCAACTCCGC CCGCTCACAG 
GTGGTGGACT TCACCAGCCC CTTCTTCTCC ACCAGCCTGG GCATCATGGT GCGGGCACGG 
GACACGGCCT CACCCATCGG TGCCTTTATG TGGCCCCTGC ACTGGTCCAC GTGGCTGGGC 
GTCTTTGCGG CCCTGCACCT CACCGCGCTC TTCCTCACCG TGTACGAGTG GCGTAGCCCC 
TACGGCCTCA CGCCACGTGG CCGCAACCGC AGCACCGTCT TCTCCTACTC CTCAGCCCTC 
AACCTGTGCT ACGCCATCCT CTTCAGACGC ACCGTGTCCA GCAAGACGCC CAAGTGCCCC 
ACGGGCCGCC TGCTCATGAA CCTCTGGGCC ATCTTCTGCC TGCTGGTGCT GTCCAGCTAC 
ACGGCCAACC TGGCTGCCGT CATGGTCGGG GACAAGACCT TCGAGGAGCT GTCGGGGATC 
CACGACCCCA AGCTGCACCA CCCGGCGCAG GGCTTCCGCT TCGGCACCGT GTGGGAGAGC 
AGCGCCGAGG CGTACATCAA GAAGAGCTTC CCCGACATGC ACGCACACAT GCGGCGCCAC 
AGCGCGCCCA CCACGCCCCG CGGCGTCGCC ATGCTCACGA GCGACCCCCC CAAGCTCAAC 
GCCTTCATCA TGGACAAGTC GCTCCTGGAC TACGAGGTCT CCATCGACGC CGACTGCAAA 
CTGCTGACCG TGGGAAAGCC CTTCGCCATT GAGGGCTATG GGATCGGACT GCCCCAGAAC 
TCGCCGCTCA CCTCCAACCT GTCCGAGTTC ATCAGCCGCT ACAAGTCCTC CGGCTTCATC 
GACCTGCTCC ACGACAAGTG GTACAAGATG GTGCCTTGCG GCAAGCGGGT CTTTGCGGTT 
ACAGAGACCC TGCAGATGAG CATCTACCAC TTCGCGGGCC TCTTCGTGTT GCTGTGCCTG 
GGCCTGGGCA GCGCTCTGCT CAGCTCGCTG GGCGAGCACG CCTTCTTCCG CCTGGCGCTG 
CCGCGCATCC GCAAGGGGAG CAGGCTGCAG TACTGGCTGC ACACCAGCCA GAAAATCCAC 
CGCGCCCTCA ACACGGAGCC ACCAGAGGGG TCGAAGGAGG AGACGGCAGA GGCGGAGCCC 
AGCGGCCCCG AGGTGGAGCA GCAGCAGCAG CAGCAGGACC AGCCAACGGC TCCGGAGGGC 
TGGAAACGGG CGCGCCGGGC CGTGGACAAG GAGCGCCGCG TGCGCTTCCT GCTGGAGCCC 
GCCGTGGTTG TGGCACCCGA AGCGGACGCG GAGGCGGAGG CTGCGCCGCG AGAGGGCCCC 
GTCTGGCTGT GCTCCTACGG CCGCCCGCCC GCCGCAAGGC CCACGGGGGC CCCCCAGCCC 
GGGGAGCTGC AGGAGCTGGA GCGCCGCATC GAAGTCGCGC GTGAGCGGCT CCGCCAGGCC 
CTGGTGCGGC GCGGCCAGCT CCTGGCACAG CTCGGGGACA GCGCACGTCA CCGGCCTCGG 
CGCTTGCTTC AGGCCAGAGC GGCCCCCGCG GAGGCCCCAC CACACTCTGG CCGACCGGGG 
AGCCAGGAAT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_619635.1
CDS	20..3151
Translation	MEFVRALWLGLALALGPGSAGGHPQPCGVLARLGGSVRLGALLPRAPLARARARAALARAALAPRLPHNLSLELVVAAPPARDPASLTRGLCQALVPPGVAALLAFPEARPELLQLHFLAAATETPVLSLLRREARAPLGAPNPFHLQLHWASPLETLLDVLVAVLQAHAWEDVGLALCRTQDPGGLVALWTSRAGRPPQLVLDLSRRDTGDAGLRARLAPMAAPVGGEAPVPAAVLLGCDIARARRVLEAVPPGPHWLLGTPLPPKALPTAGLPPGLLALGEVARPPLEAAIHDIVQLVARALGSAAQVQPKRALLPAPVNCGDLQPAGPESPGRFLARFLANTSFQGRTGPVWVTGSSQVHMSRHFKVWSLRRDPRGAPAWATVGSWRDGQLDLEPGGASARPPPPQGAQVWPKLRVVTLLEHPFVFARDPDEDGQCPAGQLCLDPGTNDSATLDALFAALANGSAPRALRKCCYGYCIDLLERLAEDTPFDFELYLVGDGKYGALRDGRWTGLVGDLLAGRAHMAVTSFSINSARSQVVDFTSPFFSTSLGIMVRARDTASPIGAFMWPLHWSTWLGVFAALHLTALFLTVYEWRSPYGLTPRGRNRSTVFSYSSALNLCYAILFRRTVSSKTPKCPTGRLLMNLWAIFCLLVLSSYTANLAAVMVGDKTFEELSGIHDPKLHHPAQGFRFGTVWESSAEAYIKKSFPDMHAHMRRHSAPTTPRGVAMLTSDPPKLNAFIMDKSLLDYEVSIDADCKLLTVGKPFAIEGYGIGLPQNSPLTSNLSEFISRYKSSGFIDLLHDKWYKMVPCGKRVFAVTETLQMSIYHFAGLFVLLCLGLGSALLSSLGEHAFFRLALPRIRKGSRLQYWLHTSQKIHRALNTEPPEGSKEETAEAEPSGPEVEQQQQQQDQPTAPEGWKRARRAVDKERRVRFLLEPAVVVAPEADAEAEAAPREGPVWLCSYGRPPAARPTGAPQPGELQELERRIEVARERLRQALVRRGQLLAQLGDSARHRPRRLLQARAAPAEAPPHSGRPGSQE

Target ORF information:

RefSeq Version	NM_138690.3
Organism	Homo sapiens(human)
Definition	Homo sapiens glutamate ionotropic receptor NMDA type subunit 3B (GRIN3B), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_138690.3

ORF Insert Sequence:

ATGGAGTTTG TGCGGGCGCT GTGGCTGGGC CTGGCGCTGG CGCTGGGGCC GGGGTCCGCG 
GGGGGCCACC CTCAGCCGTG CGGCGTCCTG GCGCGCCTCG GGGGCTCCGT GCGCCTGGGC 
GCCCTCCTGC CCCGCGCGCC TCTCGCCCGC GCCCGCGCCC GCGCCGCCCT GGCCCGGGCC 
GCCCTGGCGC CGCGGCTGCC GCACAACCTG AGCTTGGAGC TGGTGGTCGC CGCGCCCCCC 
GCCCGCGACC CCGCCTCGCT GACCCGCGGC CTGTGCCAGG CGCTGGTGCC TCCGGGCGTG 
GCGGCCCTGC TCGCCTTTCC CGAGGCTCGG CCCGAGCTGC TGCAGCTGCA CTTCCTGGCG 
GCGGCCACCG AGACCCCCGT GCTCAGCCTG CTGCGGCGGG AGGCGCGCGC GCCCCTCGGA 
GCCCCGAACC CATTCCACCT GCAGCTGCAC TGGGCCAGCC CCCTGGAGAC GCTGCTGGAT 
GTGCTGGTGG CGGTGCTGCA GGCGCACGCC TGGGAAGACG TCGGCCTGGC CCTGTGCCGC 
ACTCAGGACC CCGGCGGCCT GGTGGCCCTC TGGACAAGCC GGGCTGGCCG GCCCCCACAG 
CTGGTCCTGG ACCTAAGCCG GCGGGACACG GGAGATGCAG GACTGCGGGC ACGCCTGGCC 
CCGATGGCGG CGCCAGTGGG GGGTGAAGCA CCGGTACCCG CGGCGGTCCT CCTCGGCTGT 
GACATCGCCC GTGCCCGTCG GGTGCTGGAG GCCGTACCTC CCGGCCCCCA CTGGCTGTTG 
GGGACACCAC TGCCGCCCAA GGCCCTGCCC ACCGCGGGGC TGCCACCAGG GCTGCTGGCG 
CTGGGCGAGG TGGCACGACC CCCGCTGGAG GCCGCCATCC ATGACATTGT GCAACTGGTG 
GCCCGGGCGC TGGGCAGTGC GGCCCAGGTG CAGCCGAAGC GAGCCCTCCT CCCCGCCCCG 
GTCAACTGCG GGGACCTGCA GCCGGCCGGG CCCGAGTCCC CGGGGCGCTT CTTGGCACGG 
TTCCTGGCCA ACACGTCCTT CCAGGGCCGC ACGGGCCCCG TGTGGGTGAC AGGCAGCTCC 
CAGGTACACA TGTCTCGGCA CTTTAAGGTG TGGAGCCTTC GCCGGGACCC ACGGGGCGCC 
CCGGCCTGGG CCACGGTGGG CAGCTGGCGG GACGGCCAGC TGGACTTGGA ACCGGGAGGT 
GCCTCTGCAC GGCCCCCGCC CCCACAGGGT GCCCAGGTCT GGCCCAAGCT GCGTGTGGTA 
ACGCTGTTGG AACACCCATT TGTGTTTGCC CGTGATCCAG ACGAAGACGG GCAGTGCCCA 
GCGGGGCAGC TGTGCCTGGA CCCTGGCACC AACGACTCGG CCACCCTGGA CGCACTGTTC 
GCCGCGCTGG CCAACGGCTC AGCGCCCCGT GCCCTGCGCA AGTGCTGCTA CGGCTACTGC 
ATTGACCTGC TGGAGCGGCT GGCGGAGGAC ACGCCCTTCG ACTTCGAGCT GTACCTCGTG 
GGTGACGGCA AGTACGGCGC CCTGCGGGAC GGCCGCTGGA CCGGCCTGGT CGGGGACCTG 
CTGGCCGGCC GGGCCCACAT GGCGGTCACC AGCTTCAGTA TCAACTCCGC CCGCTCACAG 
GTGGTGGACT TCACCAGCCC CTTCTTCTCC ACCAGCCTGG GCATCATGGT GCGGGCACGG 
GACACGGCCT CACCCATCGG TGCCTTTATG TGGCCCCTGC ACTGGTCCAC GTGGCTGGGC 
GTCTTTGCGG CCCTGCACCT CACCGCGCTC TTCCTCACCG TGTACGAGTG GCGTAGCCCC 
TACGGCCTCA CGCCACGTGG CCGCAACCGC AGCACCGTCT TCTCCTACTC CTCAGCCCTC 
AACCTGTGCT ACGCCATCCT CTTCAGACGC ACCGTGTCCA GCAAGACGCC CAAGTGCCCC 
ACGGGCCGCC TGCTCATGAA CCTCTGGGCC ATCTTCTGCC TGCTGGTGCT GTCCAGCTAC 
ACGGCCAACC TGGCTGCCGT CATGGTCGGG GACAAGACCT TCGAGGAGCT GTCGGGGATC 
CACGACCCCA AGCTGCACCA CCCGGCGCAG GGCTTCCGCT TCGGCACCGT GTGGGAGAGC 
AGCGCCGAGG CGTACATCAA GAAGAGCTTC CCCGACATGC ACGCACACAT GCGGCGCCAC 
AGCGCGCCCA CCACGCCCCG CGGCGTCGCC ATGCTCACGA GCGACCCCCC CAAGCTCAAC 
GCCTTCATCA TGGACAAGTC GCTCCTGGAC TACGAGGTCT CCATCGACGC CGACTGCAAA 
CTGCTGACCG TGGGAAAGCC CTTCGCCATT GAGGGCTATG GGATCGGACT GCCCCAGAAC 
TCGCCGCTCA CCTCCAACCT GTCCGAGTTC ATCAGCCGCT ACAAGTCCTC CGGCTTCATC 
GACCTGCTCC ACGACAAGTG GTACAAGATG GTGCCTTGCG GCAAGCGGGT CTTTGCGGTT 
ACAGAGACCC TGCAGATGAG CATCTACCAC TTCGCGGGCC TCTTCGTGTT GCTGTGCCTG 
GGCCTGGGCA GCGCTCTGCT CAGCTCGCTG GGCGAGCACG CCTTCTTCCG CCTGGCGCTG 
CCGCGCATCC GCAAGGGGAG CAGGCTGCAG TACTGGCTGC ACACCAGCCA GAAAATCCAC 
CGCGCCCTCA ACACGGAGCC ACCAGAGGGG TCGAAGGAGG AGACGGCAGA GGCGGAGCCC 
AGCGGCCCCG AGGTGGAGCA GCAGCAGCAG CAGCAGGACC AGCCAACGGC TCCGGAGGGC 
TGGAAACGGG CGCGCCGGGC CGTGGACAAG GAGCGCCGCG TGCGCTTCCT GCTGGAGCCC 
GCCGTGGTTG TGGCACCCGA AGCGGACGCG GAGGCGGAGG CTGCGCCGCG AGAGGGCCCC 
GTCTGGCTGT GCTCCTACGG CCGCCCGCCC GCCGCAAGGC CCACGGGGGC CCCCCAGCCC 
GGGGAGCTGC AGGAGCTGGA GCGCCGCATC GAAGTCGCGC GTGAGCGGCT CCGCCAGGCC 
CTGGTGCGGC GCGGCCAGCT CCTGGCACAG CTCGGGGACA GCGCACGTCA CCGGCCTCGG 
CGCTTGCTTC AGGCCAGAGC GGCCCCCGCG GAGGCCCCAC CACACTCTGG CCGACCGGGG 
AGCCAGGAAT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

GRIN3B ( XM_017026243.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_016881732.1 Homo sapiens glutamate ionotropic receptor NMDA type subunit 3B (GRIN3B), transcript variant X1, mRNA.

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CloneID	OHu88181
Clone ID Related Accession (Same CDS sequence)	XM_017026243.1 , XM_017026243.2
Accession Version	XM_017026243.1	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1749bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-06-05
Organism	Homo sapiens(human)
Product	glutamate receptor ionotropic, NMDA 3B isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000019.10) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGCGGTCA CCAGCTTCAG TATCAACTCC GCCCGCTCAC AGGTGGTGGA CTTCACCAGC 
CCCTTCTTCT CCACCAGCCT GGGCATCATG GTGCGGGCAC GGGACACGGC CTCACCCATC 
GGTGCCTTTA TGTGGCCCCT GCACTGGTCC ACGTGGCTGG GCGTCTTTGC GGCCCTGCAC 
CTCACCGCGC TCTTCCTCAC CGTGTACGAG TGGCGTAGCC CCTACGGCCT CACGCCACGT 
GGCCGCAACC GCAGCACCGT CTTCTCCTAC TCCTCAGCCC TCAACCTGTG CTACGCCATC 
CTCTTCAGAC GCACCGTGTC CAGCAAGACG CCCAAGTGCC CCACGGGCCG CCTGCTCATG 
AACCTCTGGG CCATCTTCTG CCTGCTGGTG CTGTCCAGCT ACACGGCCAA CCTGGCTGCC 
GTCATGGTCG GGGACAAGAC CTTCGAGGAG CTGTCGGGGA TCCACGACCC CAAGCTGCAC 
CACCCGGCGC AGGGCTTCCG CTTCGGCACC GTGTGGGAGA GCAGCGCCGA GGCGTACATC 
AAGAAGAGCT TCCCCGACAT GCACGCACAC ATGCGGCGCC ACAGCGCGCC CACCACGCCC 
CGCGGCGTCG CCATGCTCAC GAGCGACCCC CCCAAGCTCA ACGCCTTCAT CATGGACAAG 
TCGCTCCTGG ACTACGAGGT CTCCATCGAC GCCGACTGCA AACTGCTGAC CGTGGGAAAG 
CCCTTCGCCA TTGAGGGCTA TGGGATCGGA CTGCCCCAGA ACTCGCCGCT CACCTCCAAC 
CTGTCCGAGT TCATCAGCCG CTACAAGTCC TCCGGCTTCA TCGACCTGCT CCACGACAAG 
TGGTACAAGA TGGTGCCTTG CGGCAAGCGG GTCTTTGCGG TTACAGAGAC CCTGCAGATG 
AGCATCTACC ACTTCGCGGG CCTCTTCGTG TTGCTGTGCC TGGGCCTGGG CAGCGCTCTG 
CTCAGCTCGC TGGGCGAGCA CGCCTTCTTC CGCCTGGCGC TGCCGCGCAT CCGCAAGGGG 
AGCAGGCTGC AGTACTGGCT GCACACCAGC CAGGTGGGGA GCGGGTGGGC GGCGGGCGGC 
CCCACCCCCC CCGCCTCCTC GCCAACCGGG TCTGTCTGGG GTCTTAGAAA ATCCACCGCG 
CCCTCAACAC GGAGCCACCA GAGGGGTCGA AGGAGGAGAC GGCAGAGGCG GAGCCCAGCG 
GCCCCGAGGT GGAGCAGCAG CAGCAGCAGC AGGACCAGCC AACGGCTCCG GAGGGCTGGA 
AACGGGCGCG CCGGGCCGTG GACAAGGAGC GCCGCGTGCG CTTCCTGCTG GAGCCCGCCG 
TGGTTGTGGC ACCCGAAGCG GACGCGGAGG CGGAGGCTGC GCCGCGAGAG GGCCCCGTCT 
GGCTGTGCTC CTACGGCCGC CCGCCCGCCG CAAGGCCCAC GGGGGCCCCC CAGCCCGGGG 
AGCTGCAGGA GCTGGAGCGC CGCATCGAAG TCGCGCGTGA GCGGCTCCGC CAGGCCCTGG 
TGCGGCGCGG CCAGCTCCTG GCACAGCTCG GGGACAGCGC ACGTCACCGG CCTCGGCGCT 
TGCTTCAGGC CAGAGCGGCC CCCGCGGAGG CCCCACCACA CTCTGGCCGA CCGGGGAGCC 
AGGAATGAGG CGGCAGCCGG GCCGTTTGGG CTCAAGACAC ACACACAGCG CAGTGAGCCG 
CTGTCAACAG ACAGTTTATT CTATATACAA ACACAATTTT GTACACTGCA ATTAAATAGA 
ATGGAATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_016881732.1
CDS	844..2592
Translation	MAVTSFSINSARSQVVDFTSPFFSTSLGIMVRARDTASPIGAFMWPLHWSTWLGVFAALHLTALFLTVYEWRSPYGLTPRGRNRSTVFSYSSALNLCYAILFRRTVSSKTPKCPTGRLLMNLWAIFCLLVLSSYTANLAAVMVGDKTFEELSGIHDPKLHHPAQGFRFGTVWESSAEAYIKKSFPDMHAHMRRHSAPTTPRGVAMLTSDPPKLNAFIMDKSLLDYEVSIDADCKLLTVGKPFAIEGYGIGLPQNSPLTSNLSEFISRYKSSGFIDLLHDKWYKMVPCGKRVFAVTETLQMSIYHFAGLFVLLCLGLGSALLSSLGEHAFFRLALPRIRKGSRLQYWLHTSQVGSGWAAGGPTPPASSPTGSVWGLRKSTAPSTRSHQRGRRRRRQRRSPAAPRWSSSSSSRTSQRLRRAGNGRAGPWTRSAACASCWSPPWLWHPKRTRRRRLRRERAPSGCAPTAARPPQGPRGPPSPGSCRSWSAASKSRVSGSARPWCGAASSWHSSGTAHVTGLGACFRPERPPRRPHHTLADRGARNEAAAGPFGLKTHTQRSEPLSTDSLFYIQTQFCTLQLNRME

Target ORF information:

RefSeq Version	XM_017026243.1
Organism	Homo sapiens(human)
Definition	Homo sapiens glutamate ionotropic receptor NMDA type subunit 3B (GRIN3B), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017026243.1

ORF Insert Sequence:

ATGGCGGTCA CCAGCTTCAG TATCAACTCC GCCCGCTCAC AGGTGGTGGA CTTCACCAGC 
CCCTTCTTCT CCACCAGCCT GGGCATCATG GTGCGGGCAC GGGACACGGC CTCACCCATC 
GGTGCCTTTA TGTGGCCCCT GCACTGGTCC ACGTGGCTGG GCGTCTTTGC GGCCCTGCAC 
CTCACCGCGC TCTTCCTCAC CGTGTACGAG TGGCGTAGCC CCTACGGCCT CACGCCACGT 
GGCCGCAACC GCAGCACCGT CTTCTCCTAC TCCTCAGCCC TCAACCTGTG CTACGCCATC 
CTCTTCAGAC GCACCGTGTC CAGCAAGACG CCCAAGTGCC CCACGGGCCG CCTGCTCATG 
AACCTCTGGG CCATCTTCTG CCTGCTGGTG CTGTCCAGCT ACACGGCCAA CCTGGCTGCC 
GTCATGGTCG GGGACAAGAC CTTCGAGGAG CTGTCGGGGA TCCACGACCC CAAGCTGCAC 
CACCCGGCGC AGGGCTTCCG CTTCGGCACC GTGTGGGAGA GCAGCGCCGA GGCGTACATC 
AAGAAGAGCT TCCCCGACAT GCACGCACAC ATGCGGCGCC ACAGCGCGCC CACCACGCCC 
CGCGGCGTCG CCATGCTCAC GAGCGACCCC CCCAAGCTCA ACGCCTTCAT CATGGACAAG 
TCGCTCCTGG ACTACGAGGT CTCCATCGAC GCCGACTGCA AACTGCTGAC CGTGGGAAAG 
CCCTTCGCCA TTGAGGGCTA TGGGATCGGA CTGCCCCAGA ACTCGCCGCT CACCTCCAAC 
CTGTCCGAGT TCATCAGCCG CTACAAGTCC TCCGGCTTCA TCGACCTGCT CCACGACAAG 
TGGTACAAGA TGGTGCCTTG CGGCAAGCGG GTCTTTGCGG TTACAGAGAC CCTGCAGATG 
AGCATCTACC ACTTCGCGGG CCTCTTCGTG TTGCTGTGCC TGGGCCTGGG CAGCGCTCTG 
CTCAGCTCGC TGGGCGAGCA CGCCTTCTTC CGCCTGGCGC TGCCGCGCAT CCGCAAGGGG 
AGCAGGCTGC AGTACTGGCT GCACACCAGC CAGGTGGGGA GCGGGTGGGC GGCGGGCGGC 
CCCACCCCCC CCGCCTCCTC GCCAACCGGG TCTGTCTGGG GTCTTAGAAA ATCCACCGCG 
CCCTCAACAC GGAGCCACCA GAGGGGTCGA AGGAGGAGAC GGCAGAGGCG GAGCCCAGCG 
GCCCCGAGGT GGAGCAGCAG CAGCAGCAGC AGGACCAGCC AACGGCTCCG GAGGGCTGGA 
AACGGGCGCG CCGGGCCGTG GACAAGGAGC GCCGCGTGCG CTTCCTGCTG GAGCCCGCCG 
TGGTTGTGGC ACCCGAAGCG GACGCGGAGG CGGAGGCTGC GCCGCGAGAG GGCCCCGTCT 
GGCTGTGCTC CTACGGCCGC CCGCCCGCCG CAAGGCCCAC GGGGGCCCCC CAGCCCGGGG 
AGCTGCAGGA GCTGGAGCGC CGCATCGAAG TCGCGCGTGA GCGGCTCCGC CAGGCCCTGG 
TGCGGCGCGG CCAGCTCCTG GCACAGCTCG GGGACAGCGC ACGTCACCGG CCTCGGCGCT 
TGCTTCAGGC CAGAGCGGCC CCCGCGGAGG CCCCACCACA CTCTGGCCGA CCGGGGAGCC 
AGGAATGAGG CGGCAGCCGG GCCGTTTGGG CTCAAGACAC ACACACAGCG CAGTGAGCCG 
CTGTCAACAG ACAGTTTATT CTATATACAA ACACAATTTT GTACACTGCA ATTAAATAGA 
ATGGAATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

GRIN3B ( XM_017026243.2 ) cDNA ORF clone, Homo sapiens(human) -> XP_016881732.1 Homo sapiens glutamate ionotropic receptor NMDA type subunit 3B (GRIN3B), transcript variant X1, mRNA.

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CloneID	OHu88181
Clone ID Related Accession (Same CDS sequence)	XM_017026243.1 , XM_017026243.2
Accession Version	XM_017026243.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1749bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	glutamate receptor ionotropic, NMDA 3B isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000019.10) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Mar 26, 2018 this sequence version replaced XM_017026243.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGCGGTCA CCAGCTTCAG TATCAACTCC GCCCGCTCAC AGGTGGTGGA CTTCACCAGC 
CCCTTCTTCT CCACCAGCCT GGGCATCATG GTGCGGGCAC GGGACACGGC CTCACCCATC 
GGTGCCTTTA TGTGGCCCCT GCACTGGTCC ACGTGGCTGG GCGTCTTTGC GGCCCTGCAC 
CTCACCGCGC TCTTCCTCAC CGTGTACGAG TGGCGTAGCC CCTACGGCCT CACGCCACGT 
GGCCGCAACC GCAGCACCGT CTTCTCCTAC TCCTCAGCCC TCAACCTGTG CTACGCCATC 
CTCTTCAGAC GCACCGTGTC CAGCAAGACG CCCAAGTGCC CCACGGGCCG CCTGCTCATG 
AACCTCTGGG CCATCTTCTG CCTGCTGGTG CTGTCCAGCT ACACGGCCAA CCTGGCTGCC 
GTCATGGTCG GGGACAAGAC CTTCGAGGAG CTGTCGGGGA TCCACGACCC CAAGCTGCAC 
CACCCGGCGC AGGGCTTCCG CTTCGGCACC GTGTGGGAGA GCAGCGCCGA GGCGTACATC 
AAGAAGAGCT TCCCCGACAT GCACGCACAC ATGCGGCGCC ACAGCGCGCC CACCACGCCC 
CGCGGCGTCG CCATGCTCAC GAGCGACCCC CCCAAGCTCA ACGCCTTCAT CATGGACAAG 
TCGCTCCTGG ACTACGAGGT CTCCATCGAC GCCGACTGCA AACTGCTGAC CGTGGGAAAG 
CCCTTCGCCA TTGAGGGCTA TGGGATCGGA CTGCCCCAGA ACTCGCCGCT CACCTCCAAC 
CTGTCCGAGT TCATCAGCCG CTACAAGTCC TCCGGCTTCA TCGACCTGCT CCACGACAAG 
TGGTACAAGA TGGTGCCTTG CGGCAAGCGG GTCTTTGCGG TTACAGAGAC CCTGCAGATG 
AGCATCTACC ACTTCGCGGG CCTCTTCGTG TTGCTGTGCC TGGGCCTGGG CAGCGCTCTG 
CTCAGCTCGC TGGGCGAGCA CGCCTTCTTC CGCCTGGCGC TGCCGCGCAT CCGCAAGGGG 
AGCAGGCTGC AGTACTGGCT GCACACCAGC CAGGTGGGGA GCGGGTGGGC GGCGGGCGGC 
CCCACCCCCC CCGCCTCCTC GCCAACCGGG TCTGTCTGGG GTCTTAGAAA ATCCACCGCG 
CCCTCAACAC GGAGCCACCA GAGGGGTCGA AGGAGGAGAC GGCAGAGGCG GAGCCCAGCG 
GCCCCGAGGT GGAGCAGCAG CAGCAGCAGC AGGACCAGCC AACGGCTCCG GAGGGCTGGA 
AACGGGCGCG CCGGGCCGTG GACAAGGAGC GCCGCGTGCG CTTCCTGCTG GAGCCCGCCG 
TGGTTGTGGC ACCCGAAGCG GACGCGGAGG CGGAGGCTGC GCCGCGAGAG GGCCCCGTCT 
GGCTGTGCTC CTACGGCCGC CCGCCCGCCG CAAGGCCCAC GGGGGCCCCC CAGCCCGGGG 
AGCTGCAGGA GCTGGAGCGC CGCATCGAAG TCGCGCGTGA GCGGCTCCGC CAGGCCCTGG 
TGCGGCGCGG CCAGCTCCTG GCACAGCTCG GGGACAGCGC ACGTCACCGG CCTCGGCGCT 
TGCTTCAGGC CAGAGCGGCC CCCGCGGAGG CCCCACCACA CTCTGGCCGA CCGGGGAGCC 
AGGAATGAGG CGGCAGCCGG GCCGTTTGGG CTCAAGACAC ACACACAGCG CAGTGAGCCG 
CTGTCAACAG ACAGTTTATT CTATATACAA ACACAATTTT GTACACTGCA ATTAAATAGA 
ATGGAATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_016881732.1
CDS	844..2592
Translation	MAVTSFSINSARSQVVDFTSPFFSTSLGIMVRARDTASPIGAFMWPLHWSTWLGVFAALHLTALFLTVYEWRSPYGLTPRGRNRSTVFSYSSALNLCYAILFRRTVSSKTPKCPTGRLLMNLWAIFCLLVLSSYTANLAAVMVGDKTFEELSGIHDPKLHHPAQGFRFGTVWESSAEAYIKKSFPDMHAHMRRHSAPTTPRGVAMLTSDPPKLNAFIMDKSLLDYEVSIDADCKLLTVGKPFAIEGYGIGLPQNSPLTSNLSEFISRYKSSGFIDLLHDKWYKMVPCGKRVFAVTETLQMSIYHFAGLFVLLCLGLGSALLSSLGEHAFFRLALPRIRKGSRLQYWLHTSQVGSGWAAGGPTPPASSPTGSVWGLRKSTAPSTRSHQRGRRRRRQRRSPAAPRWSSSSSSRTSQRLRRAGNGRAGPWTRSAACASCWSPPWLWHPKRTRRRRLRRERAPSGCAPTAARPPQGPRGPPSPGSCRSWSAASKSRVSGSARPWCGAASSWHSSGTAHVTGLGACFRPERPPRRPHHTLADRGARNEAAAGPFGLKTHTQRSEPLSTDSLFYIQTQFCTLQLNRME

Target ORF information:

RefSeq Version	XM_017026243.2
Organism	Homo sapiens(human)
Definition	Homo sapiens glutamate ionotropic receptor NMDA type subunit 3B (GRIN3B), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017026243.2

ORF Insert Sequence:

ATGGCGGTCA CCAGCTTCAG TATCAACTCC GCCCGCTCAC AGGTGGTGGA CTTCACCAGC 
CCCTTCTTCT CCACCAGCCT GGGCATCATG GTGCGGGCAC GGGACACGGC CTCACCCATC 
GGTGCCTTTA TGTGGCCCCT GCACTGGTCC ACGTGGCTGG GCGTCTTTGC GGCCCTGCAC 
CTCACCGCGC TCTTCCTCAC CGTGTACGAG TGGCGTAGCC CCTACGGCCT CACGCCACGT 
GGCCGCAACC GCAGCACCGT CTTCTCCTAC TCCTCAGCCC TCAACCTGTG CTACGCCATC 
CTCTTCAGAC GCACCGTGTC CAGCAAGACG CCCAAGTGCC CCACGGGCCG CCTGCTCATG 
AACCTCTGGG CCATCTTCTG CCTGCTGGTG CTGTCCAGCT ACACGGCCAA CCTGGCTGCC 
GTCATGGTCG GGGACAAGAC CTTCGAGGAG CTGTCGGGGA TCCACGACCC CAAGCTGCAC 
CACCCGGCGC AGGGCTTCCG CTTCGGCACC GTGTGGGAGA GCAGCGCCGA GGCGTACATC 
AAGAAGAGCT TCCCCGACAT GCACGCACAC ATGCGGCGCC ACAGCGCGCC CACCACGCCC 
CGCGGCGTCG CCATGCTCAC GAGCGACCCC CCCAAGCTCA ACGCCTTCAT CATGGACAAG 
TCGCTCCTGG ACTACGAGGT CTCCATCGAC GCCGACTGCA AACTGCTGAC CGTGGGAAAG 
CCCTTCGCCA TTGAGGGCTA TGGGATCGGA CTGCCCCAGA ACTCGCCGCT CACCTCCAAC 
CTGTCCGAGT TCATCAGCCG CTACAAGTCC TCCGGCTTCA TCGACCTGCT CCACGACAAG 
TGGTACAAGA TGGTGCCTTG CGGCAAGCGG GTCTTTGCGG TTACAGAGAC CCTGCAGATG 
AGCATCTACC ACTTCGCGGG CCTCTTCGTG TTGCTGTGCC TGGGCCTGGG CAGCGCTCTG 
CTCAGCTCGC TGGGCGAGCA CGCCTTCTTC CGCCTGGCGC TGCCGCGCAT CCGCAAGGGG 
AGCAGGCTGC AGTACTGGCT GCACACCAGC CAGGTGGGGA GCGGGTGGGC GGCGGGCGGC 
CCCACCCCCC CCGCCTCCTC GCCAACCGGG TCTGTCTGGG GTCTTAGAAA ATCCACCGCG 
CCCTCAACAC GGAGCCACCA GAGGGGTCGA AGGAGGAGAC GGCAGAGGCG GAGCCCAGCG 
GCCCCGAGGT GGAGCAGCAG CAGCAGCAGC AGGACCAGCC AACGGCTCCG GAGGGCTGGA 
AACGGGCGCG CCGGGCCGTG GACAAGGAGC GCCGCGTGCG CTTCCTGCTG GAGCCCGCCG 
TGGTTGTGGC ACCCGAAGCG GACGCGGAGG CGGAGGCTGC GCCGCGAGAG GGCCCCGTCT 
GGCTGTGCTC CTACGGCCGC CCGCCCGCCG CAAGGCCCAC GGGGGCCCCC CAGCCCGGGG 
AGCTGCAGGA GCTGGAGCGC CGCATCGAAG TCGCGCGTGA GCGGCTCCGC CAGGCCCTGG 
TGCGGCGCGG CCAGCTCCTG GCACAGCTCG GGGACAGCGC ACGTCACCGG CCTCGGCGCT 
TGCTTCAGGC CAGAGCGGCC CCCGCGGAGG CCCCACCACA CTCTGGCCGA CCGGGGAGCC 
AGGAATGAGG CGGCAGCCGG GCCGTTTGGG CTCAAGACAC ACACACAGCG CAGTGAGCCG 
CTGTCAACAG ACAGTTTATT CTATATACAA ACACAATTTT GTACACTGCA ATTAAATAGA 
ATGGAATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

GRIN3B missense mutation as an inherited risk factor for schizophrenia: whole-exome sequencing in a family with a familiar history of psychotic disorders.
Genetics research99e1(2017 01)
Hornig T,Gr?ning B,Kundu K,Houwaart T,Backofen R,Biber K,Normann C

Novel and rare functional genomic variants in multiple autoimmune syndrome and Sj?gren's syndrome.
Journal of translational medicine13173(2015 Jun)
Johar AS,Mastronardi C,Rojas-Villarraga A,Patel HR,Chuah A,Peng K,Higgins A,Milburn P,Palmer S,Silva-Lara MF,Velez JI,Andrews D,Field M,Huttley G,Goodnow C,Anaya JM,Arcos-Burgos M

A naturally occurring null variant of the NMDA type glutamate receptor NR3B subunit is a risk factor of schizophrenia.
PloS one10(3)e0116319(2015)
Matsuno H,Ohi K,Hashimoto R,Yamamori H,Yasuda Y,Fujimoto M,Yano-Umeda S,Saneyoshi T,Takeda M,Hayashi Y

A recently-discovered NMDA receptor gene, GRIN3B, is associated with duration mismatch negativity.
Psychiatry research218(3)356-8(2014 Aug)
Lin YT,Hsieh MH,Liu CC,Hwang TJ,Chien YL,Hwu HG,Liu CM

Variants in the ATP-binding cassette transporter (ABCA7), apolipoprotein E ?4,and the risk of late-onset Alzheimer disease in African Americans.
JAMA309(14)1483-92(2013 Apr)
Reitz C,Jun G,Naj A,Rajbhandary R,Vardarajan BN,Wang LS,Valladares O,Lin CF,Larson EB,Graff-Radford NR,Evans D,De Jager PL,Crane PK,Buxbaum JD,Murrell JR,Raj T,Ertekin-Taner N,Logue M,Baldwin CT,Green RC,Barnes LL,Cantwell LB,Fallin MD,Go RC,Griffith P,Obisesan TO,Manly JJ,Lunetta KL,Kamboh MI,Lopez OL,Bennett DA,Hendrie H,Hall KS,Goate AM,Byrd GS,Kukull WA,Foroud TM,Haines JL,Farrer LA,Pericak-Vance MA,Schellenberg GD,Mayeux R,

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GRIN3B cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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