WDFY2 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	WDFY2
Entrez Gene ID	115825
Full Name	WD repeat and FYVE domain containing 2
Synonyms	PROF,WDF2,ZFYVE22
General protein information	Preferred Names WD repeat and FYVE domain containing 2 Names WD repeat and FYVE domain-containing protein 2 WD40 and FYVE domain containing 2 WD40- and FYVE domain-containing protein 2 propeller-FYVE protein zinc finger FYVE domain-containing protein 22
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 13 Map Location: 13q14.3
Summary	This gene encodes a protein that contains two WD domains and an FYVE zinc finger region. The function of this gene is unknown. An alternatively spliced transcript variant of this gene may exist. [provided by RefSeq, Jul 2008].
Disorder MIM:	610418

mRNA and Protein(s)

mRNA	Protein	Name
XM_024449316.1	XP_024305084.1	WD repeat and FYVE domain-containing protein 2 isoform X2
XM_017020386.1	XP_016875875.1	WD repeat and FYVE domain-containing protein 2 isoform X3
NM_052950.3	NP_443182.1	WD repeat and FYVE domain-containing protein 2
XM_011534914.1	XP_011533216.1	WD repeat and FYVE domain-containing protein 2 isoform X1
XM_011534915.2	XP_011533217.1	WD repeat and FYVE domain-containing protein 2 isoform X3
NM_052950.4	NP_443182.1	WD repeat and FYVE domain-containing protein 2
XM_024449317.1	XP_024305085.1	WD repeat and FYVE domain-containing protein 2 isoform X2

Pathways from BioSystems

Homologies

Homo sapiens (human)	WDFY2	NP_443182.1
Canis lupus familiaris (dog)	WDFY2	XP_848495.3
Mus musculus (house mouse)	Wdfy2	NP_780755.2
Rattus norvegicus (Norway rat)	Wdfy2	NP_001100739.1
Danio rerio (zebrafish)	wdfy2	NP_991308.1
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP008932	XP_319687.1
Xenopus tropicalis (tropical clawed frog)	wdfy2	XP_002936770.1
Gallus gallus (chicken)	WDFY2	NP_001073218.1
Pan troglodytes (chimpanzee)	WDFY2	XP_001158979.1
Caenorhabditis elegans (roundworm)	wdfy-2	NP_495983.1
	LOC708929	XP_001106117.2
Drosophila melanogaster (fruit fly)	CG5168	NP_609400.1

Gene Ontology
Bibliography

Related articles in PubMed

Overexpression of WDFY2 inhibits prostate cancer cell growth and migration via inactivation of Akt pathway.
Wang J, Chen X, Tong S, Zhou H, Sun J, Gou Y, Wu F, Hu J, Xu J, Ding G
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine39(6)1010428317704821(2017 Jun)

CDKN2D-WDFY2 is a cancer-specific fusion gene recurrent in high-grade serous ovarian carcinoma.
Kannan K, Coarfa C, Rajapakshe K, Hawkins SM, Matzuk MM, Milosavljevic A, Yen L
PLoS genetics10(3)e1004216(2014 Mar)

Akt- and Foxo1-interacting WD-repeat-FYVE protein promotes adipogenesis.
Fritzius T, Moelling K
The EMBO journal27(9)1399-410(2008 May)

WD-repeat-propeller-FYVE protein, ProF, binds VAMP2 and protein kinase Czeta.
Fritzius T, Frey AD, Schweneker M, Mayer D, Moelling K
The FEBS journal274(6)1552-66(2007 Mar)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Our results showed that WDFY2 inhibited cancer cell colony formation and migration via suppressing Akt pathway, making it a potential new therapeutic target in prostate cancer.
Title: Overexpression of WDFY2 inhibits prostate cancer cell growth and migration via inactivation of Akt pathway.

CDKN2D-WDFY2 fusion could be an important molecular signature for understanding and classifying sub-lineages among heterogeneous high-grade serous ovarian carcinomas.
Title: CDKN2D-WDFY2 is a cancer-specific fusion gene recurrent in high-grade serous ovarian carcinoma.

presence of ProF increases the PKCzeta-dependent phosphorylation of VAMP2 in vitro
Title: WD-repeat-propeller-FYVE protein, ProF, binds VAMP2 and protein kinase Czeta.

The ProF protein partially co-localizes with EEA1 on vesicular structures and binds to the protein kinases Akt and PKCzeta/lambda (protein kinase Czeta/lambda) via its WD-repeat propeller.
Title: A WD-FYVE protein binds to the kinases Akt and PKCzeta/lambda.

WDFY2, the WD40 and FYVE domain containing protein 2, has roles in endocytosis
Title: The WD40 and FYVE domain containing protein 2 defines a class of early endosomes necessary for endocytosis.

The following WDFY2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the WDFY2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu13513	NM_052950.4 Latest version!	Homo sapiens WD repeat and FYVE domain containing 2 (WDFY2), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$189.50-$265.30 $379.00
OHu74945	XM_011534914.1 Latest version!	Homo sapiens WD repeat and FYVE domain containing 2 (WDFY2), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$223.30 $319.00
OHu74946	XM_011534915.2 Latest version!	Homo sapiens WD repeat and FYVE domain containing 2 (WDFY2), transcript variant X5, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$139.30 $199.00
OHu74946	XM_017020386.1 Latest version!	Homo sapiens WD repeat and FYVE domain containing 2 (WDFY2), transcript variant X6, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$139.30 $199.00
OHu103817	XM_024449316.1 Latest version!	Homo sapiens WD repeat and FYVE domain containing 2 (WDFY2), transcript variant X3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$223.30 $319.00
OHu103817	XM_024449317.1 Latest version!	Homo sapiens WD repeat and FYVE domain containing 2 (WDFY2), transcript variant X4, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$223.30 $319.00
View Old Accession Versions >>
OHu13513	NM_052950.3	Homo sapiens WD repeat and FYVE domain containing 2 (WDFY2), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$189.50-$265.30 $379.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

WDFY2 ( NM_052950.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_443182.1 Homo sapiens WD repeat and FYVE domain containing 2 (WDFY2), mRNA.

Price & Availability↑

CloneID	OHu13513
Clone ID Related Accession (Same CDS sequence)	NM_052950.3 , NM_052950.4
Accession Version	NM_052950.3	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1203bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-10-01
Organism	Homo sapiens(human)
Product	WD repeat and FYVE domain-containing protein 2
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DA124107.1, BC014004.2 and AL136525.17. On Sep 22, 2006 this sequence version replaced NM_052950.2. ##Evidence-Data-START## Transcript exon combination :: SRR1803615.11536.1, SRR1660809.125525.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGCGGCGG AGATCCAGCC CAAGCCTCTG ACCCGCAAGC CGATCCTGCT GCAGCGGATG 
GAGGGGTCCC AGGAGGTGGT GAATATGGCC GTGATCGTGC CCAAAGAGGA GGGCGTCATC 
AGCGTCTCCG AGGACAGGAC AGTTCGTGTT TGGTTAAAGA GAGACAGTGG ACAGTATTGG 
CCAAGCGTAT ACCATGCAAT GCCTTCTCCA TGTTCATGCA TGTCTTTTAA CCCGGAAACA 
AGAAGACTGT CCATAGGTCT AGACAATGGT ACAATCTCAG AGTTTATATT GTCAGAAGAT 
TATAACAAGA TGACTCCTGT GAAAAACTAT CAAGCGCATC AGAGCAGAGT GACGATGATC 
CTGTTTGTCC TGGAGCTGGA GTGGGTGCTG AGCACAGGAC AGGACAAGCA ATTTGCCTGG 
CACTGCTCTG AGAGTGGGCA GCGCCTGGGA GGTTATCGGA CCAGTGCTGT GGCCTCAGGC 
CTGCAATTTG ATGTTGAAAC CCGGCATGTG TTTATCGGTG ACCACTCAGG CCAAGTAACA 
ATCCTCAAAC TGGAGCAAGA AAACTGCACC CTGGTCACAA CATTCAGAGG ACACACAGGT 
GGGGTGACCG CTCTCTGTTG GGACCCAGTC CAGCGGGTGT TGTTCTCAGG CAGTTCAGAT 
CACTCTGTCA TCATGTGGGA CATCGGTGGG AGAAAAGGAA CAGCCATCGA GCTCCAAGGA 
CACAACGACA GAGTCCAGGC CCTCTCCTAT GCACAGCACA CGCGACAATT GATCTCCTGT 
GGCGGTGATG GTGGGATTGT CGTCTGGAAC ATGGACGTGG AGAGGCAGGA GACCCCTGAA 
TGGTTGGACA GTGATTCCTG CCAAAAGTGT GATCAGCCTT TCTTCTGGAA CTTCAAGCAA 
ATGTGGGACA GTAAGAAAAT TGGTCTAAGA CAGCACCACT GCCGCAAGTG TGGGAAGGCC 
GTCTGTGGCA AGTGCAGCTC CAAGCGCTCC TCCATCCCCC TGATGGGCTT CGAGTTTGAA 
GTGAGGGTCT GTGACAGCTG CCACGAGGCC ATCACAGATG AAGAACGTGC ACCCACAGCC 
ACCTTCCATG ACAGTAAACA TAACATTGTG CATGTGCATT TCGATGCAAC CAGAGGATGG 
TTACTGACTT CTGGAACTGA CAAGGTTATT AAGTTGTGGG ATATGACCCC AGTCGTGTCT 
TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_443182.1
CDS	341..1543
Translation	MAAEIQPKPLTRKPILLQRMEGSQEVVNMAVIVPKEEGVISVSEDRTVRVWLKRDSGQYWPSVYHAMPSPCSCMSFNPETRRLSIGLDNGTISEFILSEDYNKMTPVKNYQAHQSRVTMILFVLELEWVLSTGQDKQFAWHCSESGQRLGGYRTSAVASGLQFDVETRHVFIGDHSGQVTILKLEQENCTLVTTFRGHTGGVTALCWDPVQRVLFSGSSDHSVIMWDIGGRKGTAIELQGHNDRVQALSYAQHTRQLISCGGDGGIVVWNMDVERQETPEWLDSDSCQKCDQPFFWNFKQMWDSKKIGLRQHHCRKCGKAVCGKCSSKRSSIPLMGFEFEVRVCDSCHEAITDEERAPTATFHDSKHNIVHVHFDATRGWLLTSGTDKVIKLWDMTPVVS

Target ORF information:

RefSeq Version	NM_052950.3
Organism	Homo sapiens(human)
Definition	Homo sapiens WD repeat and FYVE domain containing 2 (WDFY2), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_052950.3

ORF Insert Sequence:

ATGGCGGCGG AGATCCAGCC CAAGCCTCTG ACCCGCAAGC CGATCCTGCT GCAGCGGATG 
GAGGGGTCCC AGGAGGTGGT GAATATGGCC GTGATCGTGC CCAAAGAGGA GGGCGTCATC 
AGCGTCTCCG AGGACAGGAC AGTTCGTGTT TGGTTAAAGA GAGACAGTGG ACAGTATTGG 
CCAAGCGTAT ACCATGCAAT GCCTTCTCCA TGTTCATGCA TGTCTTTTAA CCCGGAAACA 
AGAAGACTGT CCATAGGTCT AGACAATGGT ACAATCTCAG AGTTTATATT GTCAGAAGAT 
TATAACAAGA TGACTCCTGT GAAAAACTAT CAAGCGCATC AGAGCAGAGT GACGATGATC 
CTGTTTGTCC TGGAGCTGGA GTGGGTGCTG AGCACAGGAC AGGACAAGCA ATTTGCCTGG 
CACTGCTCTG AGAGTGGGCA GCGCCTGGGA GGTTATCGGA CCAGTGCTGT GGCCTCAGGC 
CTGCAATTTG ATGTTGAAAC CCGGCATGTG TTTATCGGTG ACCACTCAGG CCAAGTAACA 
ATCCTCAAAC TGGAGCAAGA AAACTGCACC CTGGTCACAA CATTCAGAGG ACACACAGGT 
GGGGTGACCG CTCTCTGTTG GGACCCAGTC CAGCGGGTGT TGTTCTCAGG CAGTTCAGAT 
CACTCTGTCA TCATGTGGGA CATCGGTGGG AGAAAAGGAA CAGCCATCGA GCTCCAAGGA 
CACAACGACA GAGTCCAGGC CCTCTCCTAT GCACAGCACA CGCGACAATT GATCTCCTGT 
GGCGGTGATG GTGGGATTGT CGTCTGGAAC ATGGACGTGG AGAGGCAGGA GACCCCTGAA 
TGGTTGGACA GTGATTCCTG CCAAAAGTGT GATCAGCCTT TCTTCTGGAA CTTCAAGCAA 
ATGTGGGACA GTAAGAAAAT TGGTCTAAGA CAGCACCACT GCCGCAAGTG TGGGAAGGCC 
GTCTGTGGCA AGTGCAGCTC CAAGCGCTCC TCCATCCCCC TGATGGGCTT CGAGTTTGAA 
GTGAGGGTCT GTGACAGCTG CCACGAGGCC ATCACAGATG AAGAACGTGC ACCCACAGCC 
ACCTTCCATG ACAGTAAACA TAACATTGTG CATGTGCATT TCGATGCAAC CAGAGGATGG 
TTACTGACTT CTGGAACTGA CAAGGTTATT AAGTTGTGGG ATATGACCCC AGTCGTGTCT 
TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

WDFY2 ( NM_052950.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_443182.1 Homo sapiens WD repeat and FYVE domain containing 2 (WDFY2), mRNA.

Price & Availability↑

CloneID	OHu13513
Clone ID Related Accession (Same CDS sequence)	NM_052950.3 , NM_052950.4
Accession Version	NM_052950.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1203bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-08-26
Organism	Homo sapiens(human)
Product	WD repeat and FYVE domain-containing protein 2
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DA124107.1, BC014004.2 and AL136525.17. On Nov 22, 2018 this sequence version replaced NM_052950.3. ##Evidence-Data-START## Transcript exon combination :: SRR1803615.11536.1, SRR1803611.69395.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000298125.7/ ENSP00000298125.4 RefSeq Select criteria :: based on conservation, expression, longest protein ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGGCGGCGG AGATCCAGCC CAAGCCTCTG ACCCGCAAGC CGATCCTGCT GCAGCGGATG 
GAGGGGTCCC AGGAGGTGGT GAATATGGCC GTGATCGTGC CCAAAGAGGA GGGCGTCATC 
AGCGTCTCCG AGGACAGGAC AGTTCGTGTT TGGTTAAAGA GAGACAGTGG ACAGTATTGG 
CCAAGCGTAT ACCATGCAAT GCCTTCTCCA TGTTCATGCA TGTCTTTTAA CCCGGAAACA 
AGAAGACTGT CCATAGGTCT AGACAATGGT ACAATCTCAG AGTTTATATT GTCAGAAGAT 
TATAACAAGA TGACTCCTGT GAAAAACTAT CAAGCGCATC AGAGCAGAGT GACGATGATC 
CTGTTTGTCC TGGAGCTGGA GTGGGTGCTG AGCACAGGAC AGGACAAGCA ATTTGCCTGG 
CACTGCTCTG AGAGTGGGCA GCGCCTGGGA GGTTATCGGA CCAGTGCTGT GGCCTCAGGC 
CTGCAATTTG ATGTTGAAAC CCGGCATGTG TTTATCGGTG ACCACTCAGG CCAAGTAACA 
ATCCTCAAAC TGGAGCAAGA AAACTGCACC CTGGTCACAA CATTCAGAGG ACACACAGGT 
GGGGTGACCG CTCTCTGTTG GGACCCAGTC CAGCGGGTGT TGTTCTCAGG CAGTTCAGAT 
CACTCTGTCA TCATGTGGGA CATCGGTGGG AGAAAAGGAA CAGCCATCGA GCTCCAAGGA 
CACAACGACA GAGTCCAGGC CCTCTCCTAT GCACAGCACA CGCGACAATT GATCTCCTGT 
GGCGGTGATG GTGGGATTGT CGTCTGGAAC ATGGACGTGG AGAGGCAGGA GACCCCTGAA 
TGGTTGGACA GTGATTCCTG CCAAAAGTGT GATCAGCCTT TCTTCTGGAA CTTCAAGCAA 
ATGTGGGACA GTAAGAAAAT TGGTCTAAGA CAGCACCACT GCCGCAAGTG TGGGAAGGCC 
GTCTGTGGCA AGTGCAGCTC CAAGCGCTCC TCCATCCCCC TGATGGGCTT CGAGTTTGAA 
GTGAGGGTCT GTGACAGCTG CCACGAGGCC ATCACAGATG AAGAACGTGC ACCCACAGCC 
ACCTTCCATG ACAGTAAACA TAACATTGTG CATGTGCATT TCGATGCAAC CAGAGGATGG 
TTACTGACTT CTGGAACTGA CAAGGTTATT AAGTTGTGGG ATATGACCCC AGTCGTGTCT 
TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_443182.1
CDS	227..1429
Translation	MAAEIQPKPLTRKPILLQRMEGSQEVVNMAVIVPKEEGVISVSEDRTVRVWLKRDSGQYWPSVYHAMPSPCSCMSFNPETRRLSIGLDNGTISEFILSEDYNKMTPVKNYQAHQSRVTMILFVLELEWVLSTGQDKQFAWHCSESGQRLGGYRTSAVASGLQFDVETRHVFIGDHSGQVTILKLEQENCTLVTTFRGHTGGVTALCWDPVQRVLFSGSSDHSVIMWDIGGRKGTAIELQGHNDRVQALSYAQHTRQLISCGGDGGIVVWNMDVERQETPEWLDSDSCQKCDQPFFWNFKQMWDSKKIGLRQHHCRKCGKAVCGKCSSKRSSIPLMGFEFEVRVCDSCHEAITDEERAPTATFHDSKHNIVHVHFDATRGWLLTSGTDKVIKLWDMTPVVS

Target ORF information:

RefSeq Version	NM_052950.4
Organism	Homo sapiens(human)
Definition	Homo sapiens WD repeat and FYVE domain containing 2 (WDFY2), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_052950.4

ORF Insert Sequence:

ATGGCGGCGG AGATCCAGCC CAAGCCTCTG ACCCGCAAGC CGATCCTGCT GCAGCGGATG 
GAGGGGTCCC AGGAGGTGGT GAATATGGCC GTGATCGTGC CCAAAGAGGA GGGCGTCATC 
AGCGTCTCCG AGGACAGGAC AGTTCGTGTT TGGTTAAAGA GAGACAGTGG ACAGTATTGG 
CCAAGCGTAT ACCATGCAAT GCCTTCTCCA TGTTCATGCA TGTCTTTTAA CCCGGAAACA 
AGAAGACTGT CCATAGGTCT AGACAATGGT ACAATCTCAG AGTTTATATT GTCAGAAGAT 
TATAACAAGA TGACTCCTGT GAAAAACTAT CAAGCGCATC AGAGCAGAGT GACGATGATC 
CTGTTTGTCC TGGAGCTGGA GTGGGTGCTG AGCACAGGAC AGGACAAGCA ATTTGCCTGG 
CACTGCTCTG AGAGTGGGCA GCGCCTGGGA GGTTATCGGA CCAGTGCTGT GGCCTCAGGC 
CTGCAATTTG ATGTTGAAAC CCGGCATGTG TTTATCGGTG ACCACTCAGG CCAAGTAACA 
ATCCTCAAAC TGGAGCAAGA AAACTGCACC CTGGTCACAA CATTCAGAGG ACACACAGGT 
GGGGTGACCG CTCTCTGTTG GGACCCAGTC CAGCGGGTGT TGTTCTCAGG CAGTTCAGAT 
CACTCTGTCA TCATGTGGGA CATCGGTGGG AGAAAAGGAA CAGCCATCGA GCTCCAAGGA 
CACAACGACA GAGTCCAGGC CCTCTCCTAT GCACAGCACA CGCGACAATT GATCTCCTGT 
GGCGGTGATG GTGGGATTGT CGTCTGGAAC ATGGACGTGG AGAGGCAGGA GACCCCTGAA 
TGGTTGGACA GTGATTCCTG CCAAAAGTGT GATCAGCCTT TCTTCTGGAA CTTCAAGCAA 
ATGTGGGACA GTAAGAAAAT TGGTCTAAGA CAGCACCACT GCCGCAAGTG TGGGAAGGCC 
GTCTGTGGCA AGTGCAGCTC CAAGCGCTCC TCCATCCCCC TGATGGGCTT CGAGTTTGAA 
GTGAGGGTCT GTGACAGCTG CCACGAGGCC ATCACAGATG AAGAACGTGC ACCCACAGCC 
ACCTTCCATG ACAGTAAACA TAACATTGTG CATGTGCATT TCGATGCAAC CAGAGGATGG 
TTACTGACTT CTGGAACTGA CAAGGTTATT AAGTTGTGGG ATATGACCCC AGTCGTGTCT 
TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

WDFY2 ( XM_011534914.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_011533216.1 Homo sapiens WD repeat and FYVE domain containing 2 (WDFY2), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OHu74945
Clone ID Related Accession (Same CDS sequence)	XM_011534914.1
Accession Version	XM_011534914.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1197bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	WD repeat and FYVE domain-containing protein 2 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000013.11) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGCGGCGG AGATCCAGCC CAAGCCTCTG ACCCGCAAGC CGATCCTGCT GCAGCGGATG 
GAGGGGTCCC AGGAGGTGGT GAATATGGCC GTGATCGTGC CCAAAGAGGA GGGCGTCATC 
AGCGTCTCCG AGGACAGGAC AGTTCGTGTT TGGTTAAAGA GAGACAGTGG ACAGTATTGG 
CCAAGCGTAT ACCATGCAAT GCCTTCTCCA TGTTCATGCA TGTCTTTTAA CCCGGAAACA 
AGAAGACTGT CCATAGGTCT AGACAATGGT ACAATCTCAG AGTTTATATT GTCAGAAGAT 
TATAACAAGA TGACTCCTGT GAAAAACTAT CAAGCGCATC AGAGCAGAGT GACGATGATC 
CTGTTTGTCC TGGAGCTGGA GTGGGTGCTG AGCACAGGAC AGGACAAGCA ATTTGCCTGG 
CACTGCTCTG AGAGTGGGCA GCGCCTGGGA GGTTATCGGA CCAGTGCTGT GGCCTCAGGC 
CTGCAATTTG ATGTTGAAAC CCGGCATGTG TTTATCGGTG ACCACTCAGG CCAAGTAACA 
ATCCTCAAAC TGGAGCAAGA AAACTGCACC CTGGTCACAA CATTCAGAGG ACACACAGGT 
GGGGTGACCG CTCTCTGTTG GGACCCAGTC CAGCGGGTGT TGTTCTCAGG CAGTTCAGAT 
CACTCTGTCA TCATGTGGGA CATCGGTGGG AGAAAAGGAA CAGCCATCGA GCTCCAAGGA 
CACAACGACA GAGTCCAGGC CCTCTCCTAT GCACAGCACA CGCGACAATT GATCTCCTGT 
GGCGGTGATG GTGGGATTGT CGTCTGGAAC ATGGACGTGG AGAGGCAGGA GACCCCTGAA 
TGGTTGGACA GTGATTCCTG CCAAAAGTGT GATCAGCCTT TCTTCTGGAA CTTCAAGCAA 
ATGTGGGACA GTAAGAAAAT TGGTCTAAGA CAGCACCACT GCCGCAAGTG TGGGAAGGCC 
GTCTGTGGCA AGTGCAGCTC CAAGCGCTCC TCCATCCCCC TGATGGGCTT CGAGTTTGAA 
GTGAGGGTCT GTGACAGCTG CCACGAGGCC ATCACAGATG AAGAACGTGC ACCCACAGCC 
ACCTTCCATG ACAGTAAACA TAACATTGTG CATGTGCATT TCGATGCAAC CAGAGGATGG 
TTACTGACTT CTGGAACTGA CAAGGTTATT AAGCCCACAG AGCCACTCAG AGGCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_011533216.1
CDS	232..1428
Translation	MAAEIQPKPLTRKPILLQRMEGSQEVVNMAVIVPKEEGVISVSEDRTVRVWLKRDSGQYWPSVYHAMPSPCSCMSFNPETRRLSIGLDNGTISEFILSEDYNKMTPVKNYQAHQSRVTMILFVLELEWVLSTGQDKQFAWHCSESGQRLGGYRTSAVASGLQFDVETRHVFIGDHSGQVTILKLEQENCTLVTTFRGHTGGVTALCWDPVQRVLFSGSSDHSVIMWDIGGRKGTAIELQGHNDRVQALSYAQHTRQLISCGGDGGIVVWNMDVERQETPEWLDSDSCQKCDQPFFWNFKQMWDSKKIGLRQHHCRKCGKAVCGKCSSKRSSIPLMGFEFEVRVCDSCHEAITDEERAPTATFHDSKHNIVHVHFDATRGWLLTSGTDKVIKPTEPLRG

Target ORF information:

RefSeq Version	XM_011534914.1
Organism	Homo sapiens(human)
Definition	Homo sapiens WD repeat and FYVE domain containing 2 (WDFY2), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011534914.1

ORF Insert Sequence:

ATGGCGGCGG AGATCCAGCC CAAGCCTCTG ACCCGCAAGC CGATCCTGCT GCAGCGGATG 
GAGGGGTCCC AGGAGGTGGT GAATATGGCC GTGATCGTGC CCAAAGAGGA GGGCGTCATC 
AGCGTCTCCG AGGACAGGAC AGTTCGTGTT TGGTTAAAGA GAGACAGTGG ACAGTATTGG 
CCAAGCGTAT ACCATGCAAT GCCTTCTCCA TGTTCATGCA TGTCTTTTAA CCCGGAAACA 
AGAAGACTGT CCATAGGTCT AGACAATGGT ACAATCTCAG AGTTTATATT GTCAGAAGAT 
TATAACAAGA TGACTCCTGT GAAAAACTAT CAAGCGCATC AGAGCAGAGT GACGATGATC 
CTGTTTGTCC TGGAGCTGGA GTGGGTGCTG AGCACAGGAC AGGACAAGCA ATTTGCCTGG 
CACTGCTCTG AGAGTGGGCA GCGCCTGGGA GGTTATCGGA CCAGTGCTGT GGCCTCAGGC 
CTGCAATTTG ATGTTGAAAC CCGGCATGTG TTTATCGGTG ACCACTCAGG CCAAGTAACA 
ATCCTCAAAC TGGAGCAAGA AAACTGCACC CTGGTCACAA CATTCAGAGG ACACACAGGT 
GGGGTGACCG CTCTCTGTTG GGACCCAGTC CAGCGGGTGT TGTTCTCAGG CAGTTCAGAT 
CACTCTGTCA TCATGTGGGA CATCGGTGGG AGAAAAGGAA CAGCCATCGA GCTCCAAGGA 
CACAACGACA GAGTCCAGGC CCTCTCCTAT GCACAGCACA CGCGACAATT GATCTCCTGT 
GGCGGTGATG GTGGGATTGT CGTCTGGAAC ATGGACGTGG AGAGGCAGGA GACCCCTGAA 
TGGTTGGACA GTGATTCCTG CCAAAAGTGT GATCAGCCTT TCTTCTGGAA CTTCAAGCAA 
ATGTGGGACA GTAAGAAAAT TGGTCTAAGA CAGCACCACT GCCGCAAGTG TGGGAAGGCC 
GTCTGTGGCA AGTGCAGCTC CAAGCGCTCC TCCATCCCCC TGATGGGCTT CGAGTTTGAA 
GTGAGGGTCT GTGACAGCTG CCACGAGGCC ATCACAGATG AAGAACGTGC ACCCACAGCC 
ACCTTCCATG ACAGTAAACA TAACATTGTG CATGTGCATT TCGATGCAAC CAGAGGATGG 
TTACTGACTT CTGGAACTGA CAAGGTTATT AAGCCCACAG AGCCACTCAG AGGCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

WDFY2 ( XM_017020386.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_016875875.1 Homo sapiens WD repeat and FYVE domain containing 2 (WDFY2), transcript variant X6, mRNA.

Price & Availability↑

CloneID	OHu74946
Clone ID Related Accession (Same CDS sequence)	XM_017020386.1 , XM_011534915.2
Accession Version	XM_017020386.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 936bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	WD repeat and FYVE domain-containing protein 2 isoform X3
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000013.11) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGCAATGCC TTGAGTTTAT ATTGTCAGAA GATTATAACA AGATGACTCC TGTGAAAAAC 
TATCAAGCGC ATCAGAGCAG AGTGACGATG ATCCTGTTTG TCCTGGAGCT GGAGTGGGTG 
CTGAGCACAG GACAGGACAA GCAATTTGCC TGGCACTGCT CTGAGAGTGG GCAGCGCCTG 
GGAGGTTATC GGACCAGTGC TGTGGCCTCA GGCCTGCAAT TTGATGTTGA AACCCGGCAT 
GTGTTTATCG GTGACCACTC AGGCCAAGTA ACAATCCTCA AACTGGAGCA AGAAAACTGC 
ACCCTGGTCA CAACATTCAG AGGACACACA GGTGGGGTGA CCGCTCTCTG TTGGGACCCA 
GTCCAGCGGG TGTTGTTCTC AGGCAGTTCA GATCACTCTG TCATCATGTG GGACATCGGT 
GGGAGAAAAG GAACAGCCAT CGAGCTCCAA GGACACAACG ACAGAGTCCA GGCCCTCTCC 
TATGCACAGC ACACGCGACA ATTGATCTCC TGTGGCGGTG ATGGTGGGAT TGTCGTCTGG 
AACATGGACG TGGAGAGGCA GGAGACCCCT GAATGGTTGG ACAGTGATTC CTGCCAAAAG 
TGTGATCAGC CTTTCTTCTG GAACTTCAAG CAAATGTGGG ACAGTAAGAA AATTGGTCTA 
AGACAGCACC ACTGCCGCAA GTGTGGGAAG GCCGTCTGTG GCAAGTGCAG CTCCAAGCGC 
TCCTCCATCC CCCTGATGGG CTTCGAGTTT GAAGTGAGGG TCTGTGACAG CTGCCACGAG 
GCCATCACAG ATGAAGAACG TGCACCCACA GCCACCTTCC ATGACAGTAA ACATAACATT 
GTGCATGTGC ATTTCGATGC AACCAGAGGA TGGTTACTGA CTTCTGGAAC TGACAAGGTT 
ATTAAGTTGT GGGATATGAC CCCAGTCGTG TCTTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_016875875.1
CDS	6412..7347
Translation	MQCLEFILSEDYNKMTPVKNYQAHQSRVTMILFVLELEWVLSTGQDKQFAWHCSESGQRLGGYRTSAVASGLQFDVETRHVFIGDHSGQVTILKLEQENCTLVTTFRGHTGGVTALCWDPVQRVLFSGSSDHSVIMWDIGGRKGTAIELQGHNDRVQALSYAQHTRQLISCGGDGGIVVWNMDVERQETPEWLDSDSCQKCDQPFFWNFKQMWDSKKIGLRQHHCRKCGKAVCGKCSSKRSSIPLMGFEFEVRVCDSCHEAITDEERAPTATFHDSKHNIVHVHFDATRGWLLTSGTDKVIKLWDMTPVVS

Target ORF information:

RefSeq Version	XM_017020386.1
Organism	Homo sapiens(human)
Definition	Homo sapiens WD repeat and FYVE domain containing 2 (WDFY2), transcript variant X6, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017020386.1

ORF Insert Sequence:

ATGCAATGCC TTGAGTTTAT ATTGTCAGAA GATTATAACA AGATGACTCC TGTGAAAAAC 
TATCAAGCGC ATCAGAGCAG AGTGACGATG ATCCTGTTTG TCCTGGAGCT GGAGTGGGTG 
CTGAGCACAG GACAGGACAA GCAATTTGCC TGGCACTGCT CTGAGAGTGG GCAGCGCCTG 
GGAGGTTATC GGACCAGTGC TGTGGCCTCA GGCCTGCAAT TTGATGTTGA AACCCGGCAT 
GTGTTTATCG GTGACCACTC AGGCCAAGTA ACAATCCTCA AACTGGAGCA AGAAAACTGC 
ACCCTGGTCA CAACATTCAG AGGACACACA GGTGGGGTGA CCGCTCTCTG TTGGGACCCA 
GTCCAGCGGG TGTTGTTCTC AGGCAGTTCA GATCACTCTG TCATCATGTG GGACATCGGT 
GGGAGAAAAG GAACAGCCAT CGAGCTCCAA GGACACAACG ACAGAGTCCA GGCCCTCTCC 
TATGCACAGC ACACGCGACA ATTGATCTCC TGTGGCGGTG ATGGTGGGAT TGTCGTCTGG 
AACATGGACG TGGAGAGGCA GGAGACCCCT GAATGGTTGG ACAGTGATTC CTGCCAAAAG 
TGTGATCAGC CTTTCTTCTG GAACTTCAAG CAAATGTGGG ACAGTAAGAA AATTGGTCTA 
AGACAGCACC ACTGCCGCAA GTGTGGGAAG GCCGTCTGTG GCAAGTGCAG CTCCAAGCGC 
TCCTCCATCC CCCTGATGGG CTTCGAGTTT GAAGTGAGGG TCTGTGACAG CTGCCACGAG 
GCCATCACAG ATGAAGAACG TGCACCCACA GCCACCTTCC ATGACAGTAA ACATAACATT 
GTGCATGTGC ATTTCGATGC AACCAGAGGA TGGTTACTGA CTTCTGGAAC TGACAAGGTT 
ATTAAGTTGT GGGATATGAC CCCAGTCGTG TCTTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

WDFY2 ( XM_011534915.2 ) cDNA ORF clone, Homo sapiens(human) -> XP_011533217.1 Homo sapiens WD repeat and FYVE domain containing 2 (WDFY2), transcript variant X5, mRNA.

Price & Availability↑

CloneID	OHu74946
Clone ID Related Accession (Same CDS sequence)	XM_017020386.1 , XM_011534915.2
Accession Version	XM_011534915.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 936bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	WD repeat and FYVE domain-containing protein 2 isoform X3
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000013.11) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 6, 2016 this sequence version replaced XM_011534915.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGCAATGCC TTGAGTTTAT ATTGTCAGAA GATTATAACA AGATGACTCC TGTGAAAAAC 
TATCAAGCGC ATCAGAGCAG AGTGACGATG ATCCTGTTTG TCCTGGAGCT GGAGTGGGTG 
CTGAGCACAG GACAGGACAA GCAATTTGCC TGGCACTGCT CTGAGAGTGG GCAGCGCCTG 
GGAGGTTATC GGACCAGTGC TGTGGCCTCA GGCCTGCAAT TTGATGTTGA AACCCGGCAT 
GTGTTTATCG GTGACCACTC AGGCCAAGTA ACAATCCTCA AACTGGAGCA AGAAAACTGC 
ACCCTGGTCA CAACATTCAG AGGACACACA GGTGGGGTGA CCGCTCTCTG TTGGGACCCA 
GTCCAGCGGG TGTTGTTCTC AGGCAGTTCA GATCACTCTG TCATCATGTG GGACATCGGT 
GGGAGAAAAG GAACAGCCAT CGAGCTCCAA GGACACAACG ACAGAGTCCA GGCCCTCTCC 
TATGCACAGC ACACGCGACA ATTGATCTCC TGTGGCGGTG ATGGTGGGAT TGTCGTCTGG 
AACATGGACG TGGAGAGGCA GGAGACCCCT GAATGGTTGG ACAGTGATTC CTGCCAAAAG 
TGTGATCAGC CTTTCTTCTG GAACTTCAAG CAAATGTGGG ACAGTAAGAA AATTGGTCTA 
AGACAGCACC ACTGCCGCAA GTGTGGGAAG GCCGTCTGTG GCAAGTGCAG CTCCAAGCGC 
TCCTCCATCC CCCTGATGGG CTTCGAGTTT GAAGTGAGGG TCTGTGACAG CTGCCACGAG 
GCCATCACAG ATGAAGAACG TGCACCCACA GCCACCTTCC ATGACAGTAA ACATAACATT 
GTGCATGTGC ATTTCGATGC AACCAGAGGA TGGTTACTGA CTTCTGGAAC TGACAAGGTT 
ATTAAGTTGT GGGATATGAC CCCAGTCGTG TCTTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_011533217.1
CDS	688..1623
Translation	MQCLEFILSEDYNKMTPVKNYQAHQSRVTMILFVLELEWVLSTGQDKQFAWHCSESGQRLGGYRTSAVASGLQFDVETRHVFIGDHSGQVTILKLEQENCTLVTTFRGHTGGVTALCWDPVQRVLFSGSSDHSVIMWDIGGRKGTAIELQGHNDRVQALSYAQHTRQLISCGGDGGIVVWNMDVERQETPEWLDSDSCQKCDQPFFWNFKQMWDSKKIGLRQHHCRKCGKAVCGKCSSKRSSIPLMGFEFEVRVCDSCHEAITDEERAPTATFHDSKHNIVHVHFDATRGWLLTSGTDKVIKLWDMTPVVS

Target ORF information:

RefSeq Version	XM_011534915.2
Organism	Homo sapiens(human)
Definition	Homo sapiens WD repeat and FYVE domain containing 2 (WDFY2), transcript variant X5, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011534915.2

ORF Insert Sequence:

ATGCAATGCC TTGAGTTTAT ATTGTCAGAA GATTATAACA AGATGACTCC TGTGAAAAAC 
TATCAAGCGC ATCAGAGCAG AGTGACGATG ATCCTGTTTG TCCTGGAGCT GGAGTGGGTG 
CTGAGCACAG GACAGGACAA GCAATTTGCC TGGCACTGCT CTGAGAGTGG GCAGCGCCTG 
GGAGGTTATC GGACCAGTGC TGTGGCCTCA GGCCTGCAAT TTGATGTTGA AACCCGGCAT 
GTGTTTATCG GTGACCACTC AGGCCAAGTA ACAATCCTCA AACTGGAGCA AGAAAACTGC 
ACCCTGGTCA CAACATTCAG AGGACACACA GGTGGGGTGA CCGCTCTCTG TTGGGACCCA 
GTCCAGCGGG TGTTGTTCTC AGGCAGTTCA GATCACTCTG TCATCATGTG GGACATCGGT 
GGGAGAAAAG GAACAGCCAT CGAGCTCCAA GGACACAACG ACAGAGTCCA GGCCCTCTCC 
TATGCACAGC ACACGCGACA ATTGATCTCC TGTGGCGGTG ATGGTGGGAT TGTCGTCTGG 
AACATGGACG TGGAGAGGCA GGAGACCCCT GAATGGTTGG ACAGTGATTC CTGCCAAAAG 
TGTGATCAGC CTTTCTTCTG GAACTTCAAG CAAATGTGGG ACAGTAAGAA AATTGGTCTA 
AGACAGCACC ACTGCCGCAA GTGTGGGAAG GCCGTCTGTG GCAAGTGCAG CTCCAAGCGC 
TCCTCCATCC CCCTGATGGG CTTCGAGTTT GAAGTGAGGG TCTGTGACAG CTGCCACGAG 
GCCATCACAG ATGAAGAACG TGCACCCACA GCCACCTTCC ATGACAGTAA ACATAACATT 
GTGCATGTGC ATTTCGATGC AACCAGAGGA TGGTTACTGA CTTCTGGAAC TGACAAGGTT 
ATTAAGTTGT GGGATATGAC CCCAGTCGTG TCTTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

WDFY2 ( XM_024449316.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_024305084.1 Homo sapiens WD repeat and FYVE domain containing 2 (WDFY2), transcript variant X3, mRNA.

Price & Availability↑

CloneID	OHu103817
Clone ID Related Accession (Same CDS sequence)	XM_024449316.1 , XM_024449317.1
Accession Version	XM_024449316.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1005bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	WD repeat and FYVE domain-containing protein 2 isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000013.11) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGCCTTCTC CATGTTCATG CATGTCTTTT AACCCGGAAA CAAGAAGACT GTCCATAGGT 
CTAGACAATG GTACAATCTC AGAGTTTATA TTGTCAGAAG ATTATAACAA GATGACTCCT 
GTGAAAAACT ATCAAGCGCA TCAGAGCAGA GTGACGATGA TCCTGTTTGT CCTGGAGCTG 
GAGTGGGTGC TGAGCACAGG ACAGGACAAG CAATTTGCCT GGCACTGCTC TGAGAGTGGG 
CAGCGCCTGG GAGGTTATCG GACCAGTGCT GTGGCCTCAG GCCTGCAATT TGATGTTGAA 
ACCCGGCATG TGTTTATCGG TGACCACTCA GGCCAAGTAA CAATCCTCAA ACTGGAGCAA 
GAAAACTGCA CCCTGGTCAC AACATTCAGA GGACACACAG GTGGGGTGAC CGCTCTCTGT 
TGGGACCCAG TCCAGCGGGT GTTGTTCTCA GGCAGTTCAG ATCACTCTGT CATCATGTGG 
GACATCGGTG GGAGAAAAGG AACAGCCATC GAGCTCCAAG GACACAACGA CAGAGTCCAG 
GCCCTCTCCT ATGCACAGCA CACGCGACAA TTGATCTCCT GTGGCGGTGA TGGTGGGATT 
GTCGTCTGGA ACATGGACGT GGAGAGGCAG GAGACCCCTG AATGGTTGGA CAGTGATTCC 
TGCCAAAAGT GTGATCAGCC TTTCTTCTGG AACTTCAAGC AAATGTGGGA CAGTAAGAAA 
ATTGGTCTAA GACAGCACCA CTGCCGCAAG TGTGGGAAGG CCGTCTGTGG CAAGTGCAGC 
TCCAAGCGCT CCTCCATCCC CCTGATGGGC TTCGAGTTTG AAGTGAGGGT CTGTGACAGC 
TGCCACGAGG CCATCACAGA TGAAGAACGT GCACCCACAG CCACCTTCCA TGACAGTAAA 
CATAACATTG TGCATGTGCA TTTCGATGCA ACCAGAGGAT GGTTACTGAC TTCTGGAACT 
GACAAGGTTA TTAAGTTGTG GGATATGACC CCAGTCGTGT CTTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_024305084.1
CDS	6417..7421
Translation	MPSPCSCMSFNPETRRLSIGLDNGTISEFILSEDYNKMTPVKNYQAHQSRVTMILFVLELEWVLSTGQDKQFAWHCSESGQRLGGYRTSAVASGLQFDVETRHVFIGDHSGQVTILKLEQENCTLVTTFRGHTGGVTALCWDPVQRVLFSGSSDHSVIMWDIGGRKGTAIELQGHNDRVQALSYAQHTRQLISCGGDGGIVVWNMDVERQETPEWLDSDSCQKCDQPFFWNFKQMWDSKKIGLRQHHCRKCGKAVCGKCSSKRSSIPLMGFEFEVRVCDSCHEAITDEERAPTATFHDSKHNIVHVHFDATRGWLLTSGTDKVIKLWDMTPVVS

Target ORF information:

RefSeq Version	XM_024449316.1
Organism	Homo sapiens(human)
Definition	Homo sapiens WD repeat and FYVE domain containing 2 (WDFY2), transcript variant X3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_024449316.1

ORF Insert Sequence:

ATGCCTTCTC CATGTTCATG CATGTCTTTT AACCCGGAAA CAAGAAGACT GTCCATAGGT 
CTAGACAATG GTACAATCTC AGAGTTTATA TTGTCAGAAG ATTATAACAA GATGACTCCT 
GTGAAAAACT ATCAAGCGCA TCAGAGCAGA GTGACGATGA TCCTGTTTGT CCTGGAGCTG 
GAGTGGGTGC TGAGCACAGG ACAGGACAAG CAATTTGCCT GGCACTGCTC TGAGAGTGGG 
CAGCGCCTGG GAGGTTATCG GACCAGTGCT GTGGCCTCAG GCCTGCAATT TGATGTTGAA 
ACCCGGCATG TGTTTATCGG TGACCACTCA GGCCAAGTAA CAATCCTCAA ACTGGAGCAA 
GAAAACTGCA CCCTGGTCAC AACATTCAGA GGACACACAG GTGGGGTGAC CGCTCTCTGT 
TGGGACCCAG TCCAGCGGGT GTTGTTCTCA GGCAGTTCAG ATCACTCTGT CATCATGTGG 
GACATCGGTG GGAGAAAAGG AACAGCCATC GAGCTCCAAG GACACAACGA CAGAGTCCAG 
GCCCTCTCCT ATGCACAGCA CACGCGACAA TTGATCTCCT GTGGCGGTGA TGGTGGGATT 
GTCGTCTGGA ACATGGACGT GGAGAGGCAG GAGACCCCTG AATGGTTGGA CAGTGATTCC 
TGCCAAAAGT GTGATCAGCC TTTCTTCTGG AACTTCAAGC AAATGTGGGA CAGTAAGAAA 
ATTGGTCTAA GACAGCACCA CTGCCGCAAG TGTGGGAAGG CCGTCTGTGG CAAGTGCAGC 
TCCAAGCGCT CCTCCATCCC CCTGATGGGC TTCGAGTTTG AAGTGAGGGT CTGTGACAGC 
TGCCACGAGG CCATCACAGA TGAAGAACGT GCACCCACAG CCACCTTCCA TGACAGTAAA 
CATAACATTG TGCATGTGCA TTTCGATGCA ACCAGAGGAT GGTTACTGAC TTCTGGAACT 
GACAAGGTTA TTAAGTTGTG GGATATGACC CCAGTCGTGT CTTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

WDFY2 ( XM_024449317.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_024305085.1 Homo sapiens WD repeat and FYVE domain containing 2 (WDFY2), transcript variant X4, mRNA.

Price & Availability↑

CloneID	OHu103817
Clone ID Related Accession (Same CDS sequence)	XM_024449316.1 , XM_024449317.1
Accession Version	XM_024449317.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1005bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	WD repeat and FYVE domain-containing protein 2 isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000013.11) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGCCTTCTC CATGTTCATG CATGTCTTTT AACCCGGAAA CAAGAAGACT GTCCATAGGT 
CTAGACAATG GTACAATCTC AGAGTTTATA TTGTCAGAAG ATTATAACAA GATGACTCCT 
GTGAAAAACT ATCAAGCGCA TCAGAGCAGA GTGACGATGA TCCTGTTTGT CCTGGAGCTG 
GAGTGGGTGC TGAGCACAGG ACAGGACAAG CAATTTGCCT GGCACTGCTC TGAGAGTGGG 
CAGCGCCTGG GAGGTTATCG GACCAGTGCT GTGGCCTCAG GCCTGCAATT TGATGTTGAA 
ACCCGGCATG TGTTTATCGG TGACCACTCA GGCCAAGTAA CAATCCTCAA ACTGGAGCAA 
GAAAACTGCA CCCTGGTCAC AACATTCAGA GGACACACAG GTGGGGTGAC CGCTCTCTGT 
TGGGACCCAG TCCAGCGGGT GTTGTTCTCA GGCAGTTCAG ATCACTCTGT CATCATGTGG 
GACATCGGTG GGAGAAAAGG AACAGCCATC GAGCTCCAAG GACACAACGA CAGAGTCCAG 
GCCCTCTCCT ATGCACAGCA CACGCGACAA TTGATCTCCT GTGGCGGTGA TGGTGGGATT 
GTCGTCTGGA ACATGGACGT GGAGAGGCAG GAGACCCCTG AATGGTTGGA CAGTGATTCC 
TGCCAAAAGT GTGATCAGCC TTTCTTCTGG AACTTCAAGC AAATGTGGGA CAGTAAGAAA 
ATTGGTCTAA GACAGCACCA CTGCCGCAAG TGTGGGAAGG CCGTCTGTGG CAAGTGCAGC 
TCCAAGCGCT CCTCCATCCC CCTGATGGGC TTCGAGTTTG AAGTGAGGGT CTGTGACAGC 
TGCCACGAGG CCATCACAGA TGAAGAACGT GCACCCACAG CCACCTTCCA TGACAGTAAA 
CATAACATTG TGCATGTGCA TTTCGATGCA ACCAGAGGAT GGTTACTGAC TTCTGGAACT 
GACAAGGTTA TTAAGTTGTG GGATATGACC CCAGTCGTGT CTTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_024305085.1
CDS	268..1272
Translation	MPSPCSCMSFNPETRRLSIGLDNGTISEFILSEDYNKMTPVKNYQAHQSRVTMILFVLELEWVLSTGQDKQFAWHCSESGQRLGGYRTSAVASGLQFDVETRHVFIGDHSGQVTILKLEQENCTLVTTFRGHTGGVTALCWDPVQRVLFSGSSDHSVIMWDIGGRKGTAIELQGHNDRVQALSYAQHTRQLISCGGDGGIVVWNMDVERQETPEWLDSDSCQKCDQPFFWNFKQMWDSKKIGLRQHHCRKCGKAVCGKCSSKRSSIPLMGFEFEVRVCDSCHEAITDEERAPTATFHDSKHNIVHVHFDATRGWLLTSGTDKVIKLWDMTPVVS

Target ORF information:

RefSeq Version	XM_024449317.1
Organism	Homo sapiens(human)
Definition	Homo sapiens WD repeat and FYVE domain containing 2 (WDFY2), transcript variant X4, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_024449317.1

ORF Insert Sequence:

ATGCCTTCTC CATGTTCATG CATGTCTTTT AACCCGGAAA CAAGAAGACT GTCCATAGGT 
CTAGACAATG GTACAATCTC AGAGTTTATA TTGTCAGAAG ATTATAACAA GATGACTCCT 
GTGAAAAACT ATCAAGCGCA TCAGAGCAGA GTGACGATGA TCCTGTTTGT CCTGGAGCTG 
GAGTGGGTGC TGAGCACAGG ACAGGACAAG CAATTTGCCT GGCACTGCTC TGAGAGTGGG 
CAGCGCCTGG GAGGTTATCG GACCAGTGCT GTGGCCTCAG GCCTGCAATT TGATGTTGAA 
ACCCGGCATG TGTTTATCGG TGACCACTCA GGCCAAGTAA CAATCCTCAA ACTGGAGCAA 
GAAAACTGCA CCCTGGTCAC AACATTCAGA GGACACACAG GTGGGGTGAC CGCTCTCTGT 
TGGGACCCAG TCCAGCGGGT GTTGTTCTCA GGCAGTTCAG ATCACTCTGT CATCATGTGG 
GACATCGGTG GGAGAAAAGG AACAGCCATC GAGCTCCAAG GACACAACGA CAGAGTCCAG 
GCCCTCTCCT ATGCACAGCA CACGCGACAA TTGATCTCCT GTGGCGGTGA TGGTGGGATT 
GTCGTCTGGA ACATGGACGT GGAGAGGCAG GAGACCCCTG AATGGTTGGA CAGTGATTCC 
TGCCAAAAGT GTGATCAGCC TTTCTTCTGG AACTTCAAGC AAATGTGGGA CAGTAAGAAA 
ATTGGTCTAA GACAGCACCA CTGCCGCAAG TGTGGGAAGG CCGTCTGTGG CAAGTGCAGC 
TCCAAGCGCT CCTCCATCCC CCTGATGGGC TTCGAGTTTG AAGTGAGGGT CTGTGACAGC 
TGCCACGAGG CCATCACAGA TGAAGAACGT GCACCCACAG CCACCTTCCA TGACAGTAAA 
CATAACATTG TGCATGTGCA TTTCGATGCA ACCAGAGGAT GGTTACTGAC TTCTGGAACT 
GACAAGGTTA TTAAGTTGTG GGATATGACC CCAGTCGTGT CTTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Overexpression of WDFY2 inhibits prostate cancer cell growth and migration via inactivation of Akt pathway.
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine39(6)1010428317704821(2017 Jun)
Wang J,Chen X,Tong S,Zhou H,Sun J,Gou Y,Wu F,Hu J,Xu J,Ding G

CDKN2D-WDFY2 is a cancer-specific fusion gene recurrent in high-grade serous ovarian carcinoma.
PLoS genetics10(3)e1004216(2014 Mar)
Kannan K,Coarfa C,Rajapakshe K,Hawkins SM,Matzuk MM,Milosavljevic A,Yen L

Akt- and Foxo1-interacting WD-repeat-FYVE protein promotes adipogenesis.
The EMBO journal27(9)1399-410(2008 May)
Fritzius T,Moelling K

WD-repeat-propeller-FYVE protein, ProF, binds VAMP2 and protein kinase Czeta.
The FEBS journal274(6)1552-66(2007 Mar)
Fritzius T,Frey AD,Schweneker M,Mayer D,Moelling K

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WDFY2 cDNA ORF clone, Homo sapiens(human)

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Clones

gRNAs

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Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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