DIS3L cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	DIS3L
Entrez Gene ID	115752
Full Name	DIS3 like exosome 3'-5' exoribonuclease
Synonyms	DIS3L1
General protein information	Preferred Names DIS3 like exosome 3'-5' exoribonuclease Names DIS3-like exonuclease 1 DIS3 mitotic control homolog-like
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 15 Map Location: 15q22.31
Summary	The cytoplasmic RNA exosome complex degrades unstable mRNAs and is involved in the regular turnover of other mRNAs. The protein encoded by this gene contains 3'-5' exoribonuclease activity and is a catalytic component of this complex. [provided by RefSeq, May 2016].
Disorder MIM:	614183

mRNA and Protein(s)

mRNA	Protein	Name
NM_001323937.1	NP_001310866.1	DIS3-like exonuclease 1 isoform 5
NM_001323940.1	NP_001310869.1	DIS3-like exonuclease 1 isoform 4
NM_001323941.2	NP_001310870.1	DIS3-like exonuclease 1 isoform 3
NM_001323945.2	NP_001310874.1	DIS3-like exonuclease 1 isoform 2
NM_001323938.2	NP_001310867.1	DIS3-like exonuclease 1 isoform 3
NM_001323937.2	NP_001310866.1	DIS3-like exonuclease 1 isoform 5
XM_005254147.3	XP_005254204.1	DIS3-like exonuclease 1 isoform X1
XM_005254145.2	XP_005254202.1	DIS3-like exonuclease 1 isoform X1
NM_001323946.1	NP_001310875.1	DIS3-like exonuclease 1 isoform 3
NM_001323936.2	NP_001310865.1	DIS3-like exonuclease 1 isoform 2
NM_001143688.3	NP_001137160.1	DIS3-like exonuclease 1 isoform 1
NM_133375.5	NP_588616.1	DIS3-like exonuclease 1 isoform 2
NM_001323943.2	NP_001310872.1	DIS3-like exonuclease 1 isoform 4
XM_005254146.4	XP_005254203.1	DIS3-like exonuclease 1 isoform X1
NM_001143688.2	NP_001137160.1	DIS3-like exonuclease 1 isoform 1
NM_001323939.1	NP_001310868.1	DIS3-like exonuclease 1 isoform 3
NM_001323943.1	NP_001310872.1	DIS3-like exonuclease 1 isoform 4
NM_133375.4	NP_588616.1	DIS3-like exonuclease 1 isoform 2
NM_001323944.1	NP_001310873.1	DIS3-like exonuclease 1 isoform 6
NM_001323945.1	NP_001310874.1	DIS3-like exonuclease 1 isoform 2
NM_001323940.2	NP_001310869.1	DIS3-like exonuclease 1 isoform 4
NM_001323939.2	NP_001310868.1	DIS3-like exonuclease 1 isoform 3
NM_001143688.1	NP_001137160.1	DIS3-like exonuclease 1 isoform 1
XM_005254146.3	XP_005254203.1	DIS3-like exonuclease 1 isoform X1
NM_001323938.1	NP_001310867.1	DIS3-like exonuclease 1 isoform 3
NM_001323936.1	NP_001310865.1	DIS3-like exonuclease 1 isoform 2
NM_001323948.1	NP_001310877.1	DIS3-like exonuclease 1 isoform 7
NM_001323948.2	NP_001310877.1	DIS3-like exonuclease 1 isoform 7
NM_001323946.2	NP_001310875.1	DIS3-like exonuclease 1 isoform 3
NM_001323944.2	NP_001310873.1	DIS3-like exonuclease 1 isoform 6
NM_133375.3	NP_588616.1	DIS3-like exonuclease 1 isoform 2
NM_001323941.1	NP_001310870.1	DIS3-like exonuclease 1 isoform 3

Pathways from BioSystems

Homologies

	DIS3L	XP_001110092.1
Bos taurus (cattle)	DIS3L	NP_001071624.1
Mus musculus (house mouse)	Dis3l	NP_001001295.2
Canis lupus familiaris (dog)	DIS3L	XP_005638760.1
Rattus norvegicus (Norway rat)	Dis3l	NP_001008381.1
Danio rerio (zebrafish)	dis3l	NP_001103928.1
Gallus gallus (chicken)	DIS3L	XP_003641875.2
Xenopus tropicalis (tropical clawed frog)	dis3l	NP_001072835.1
Homo sapiens (human)	DIS3L	NP_001137160.1
Pan troglodytes (chimpanzee)	DIS3L	XP_001174669.1

Gene Ontology
Bibliography

Related articles in PubMed

Genome-based exome sequencing analysis identifies GYG1, DIS3L and DDRGK1 are associated with myocardial infarction in Koreans.
Lee JY, Moon S, Kim YK, Lee SH, Lee BS, Park MY, Park JE, Jang Y, Han BG
Journal of genetics96(6)1041-1046(2017 Dec)

Discovery of genetic biomarkers contributing to variation in drug response of cytidine analogues using human lymphoblastoid cell lines.
Li L, Fridley BL, Kalari K, Niu N, Jenkins G, Batzler A, Abo RP, Schaid D, Wang L
BMC genomics1593(2014 Feb)

Exonuclease hDIS3L2 specifies an exosome-independent 3'-5' degradation pathway of human cytoplasmic mRNA.
Lubas M, Damgaard CK, Tomecki R, Cysewski D, Jensen TH, Dziembowski A
The EMBO journal32(13)1855-68(2013 Jul)

The human core exosome interacts with differentially localized processive RNases: hDIS3 and hDIS3L.
Tomecki R, Kristiansen MS, Lykke-Andersen S, Chlebowski A, Larsen KM, Szczesny RJ, Drazkowska K, Pastula A, Andersen JS, Stepien PP, Dziembowski A, Jensen TH
The EMBO journal29(14)2342-57(2010 Jul)

Dis3-like 1: a novel exoribonuclease associated with the human exosome.
Staals RH, Bronkhorst AW, Schilders G, Slomovic S, Schuster G, Heck AJ, Raijmakers R, Pruijn GJ
The EMBO journal29(14)2358-67(2010 Jul)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Data show that hDIS3 and hDIS3L are active exonucleases, but only hDIS3 has retained endonucleolytic activity, and suggest that three different ribonucleases can serve as catalytic subunits for the exosome in human cells.
Title: The human core exosome interacts with differentially localized processive RNases: hDIS3 and hDIS3L.

Data indicate that hDis3L1 is a novel exosome-associated exoribonuclease in the cytoplasm of human cells.
Title: Dis3-like 1: a novel exoribonuclease associated with the human exosome.

The following DIS3L gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the DIS3L cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu09540	NM_001143688.3 Latest version!	Homo sapiens DIS3 like exosome 3'-5' exoribonuclease (DIS3L), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$399.50-$559.30 $799.00
OHu09544	NM_001323936.2 Latest version!	Homo sapiens DIS3 like exosome 3'-5' exoribonuclease (DIS3L), transcript variant 3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$339.50-$475.30 $679.00
OHu09544	NM_001323945.2 Latest version!	Homo sapiens DIS3 like exosome 3'-5' exoribonuclease (DIS3L), transcript variant 11, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$339.50-$475.30 $679.00
OHu09544	NM_133375.5 Latest version!	Homo sapiens DIS3 like exosome 3'-5' exoribonuclease (DIS3L), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$339.50-$475.30 $679.00
OHu09544	XM_005254147.3 Latest version!	Homo sapiens DIS3 like exosome 3'-5' exoribonuclease (DIS3L), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$339.50-$475.30 $679.00
OHu09544	XM_005254145.2 Latest version!	Homo sapiens DIS3 like exosome 3'-5' exoribonuclease (DIS3L), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$339.50-$475.30 $679.00
OHu82920	NM_001323939.2 Latest version!	Homo sapiens DIS3 like exosome 3'-5' exoribonuclease (DIS3L), transcript variant 6, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	10-12	$475.30 $679.00
OHu82920	NM_001323938.2 Latest version!	Homo sapiens DIS3 like exosome 3'-5' exoribonuclease (DIS3L), transcript variant 5, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	10-12	$475.30 $679.00
OHu82920	NM_001323941.2 Latest version!	Homo sapiens DIS3 like exosome 3'-5' exoribonuclease (DIS3L), transcript variant 8, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	10-12	$475.30 $679.00
OHu82920	NM_001323946.2 Latest version!	Homo sapiens DIS3 like exosome 3'-5' exoribonuclease (DIS3L), transcript variant 12, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	10-12	$475.30 $679.00
OHu48095	XM_005254146.4 Latest version!	Homo sapiens DIS3 like exosome 3'-5' exoribonuclease (DIS3L), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	12-14	$475.30 $679.00
OHu82921	NM_001323937.2 Latest version!	Homo sapiens DIS3 like exosome 3'-5' exoribonuclease (DIS3L), transcript variant 4, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	14-16	$475.30 $679.00
OHu82922	NM_001323948.2 Latest version!	Homo sapiens DIS3 like exosome 3'-5' exoribonuclease (DIS3L), transcript variant 13, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	14-16	$475.30 $679.00
OHu82923	NM_001323943.2 Latest version!	Homo sapiens DIS3 like exosome 3'-5' exoribonuclease (DIS3L), transcript variant 9, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	14-16	$391.30 $559.00
OHu82923	NM_001323940.2 Latest version!	Homo sapiens DIS3 like exosome 3'-5' exoribonuclease (DIS3L), transcript variant 7, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	14-16	$391.30 $559.00
OHu48094	NM_001323944.2 Latest version!	Homo sapiens DIS3 like exosome 3'-5' exoribonuclease (DIS3L), transcript variant 10, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	20	$559.30 $799.00
View Old Accession Versions >>
OHu82921	NM_001323937.1	Homo sapiens DIS3 like exosome 3'-5' exoribonuclease (DIS3L), transcript variant 4, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	14-16	$475.30 $679.00
OHu09540	NM_001143688.2	Homo sapiens DIS3 like exosome 3'-5' exoribonuclease (DIS3L), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$399.50-$559.30 $799.00
OHu82923	NM_001323943.1	Homo sapiens DIS3 like exosome 3'-5' exoribonuclease (DIS3L), transcript variant 9, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	14-16	$391.30 $559.00
OHu09544	NM_133375.4	Homo sapiens DIS3 like exosome 3'-5' exoribonuclease (DIS3L), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$339.50-$475.30 $679.00
OHu09544	NM_001323945.1	Homo sapiens DIS3 like exosome 3'-5' exoribonuclease (DIS3L), transcript variant 11, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$339.50-$475.30 $679.00
OHu82923	NM_001323940.1	Homo sapiens DIS3 like exosome 3'-5' exoribonuclease (DIS3L), transcript variant 7, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	14-16	$391.30 $559.00
OHu82920	NM_001323939.1	Homo sapiens DIS3 like exosome 3'-5' exoribonuclease (DIS3L), transcript variant 6, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	10-12	$475.30 $679.00
OHu09540	NM_001143688.1	Homo sapiens DIS3 like exosome 3'-5' exoribonuclease (DIS3L), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$399.50-$559.30 $799.00
OHu48095	XM_005254146.3	Homo sapiens DIS3 like exosome 3'-5' exoribonuclease (DIS3L), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	12-14	$475.30 $679.00
OHu82920	NM_001323938.1	Homo sapiens DIS3 like exosome 3'-5' exoribonuclease (DIS3L), transcript variant 5, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	10-12	$475.30 $679.00
OHu09544	NM_001323936.1	Homo sapiens DIS3 like exosome 3'-5' exoribonuclease (DIS3L), transcript variant 3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$339.50-$475.30 $679.00
OHu82922	NM_001323948.1	Homo sapiens DIS3 like exosome 3'-5' exoribonuclease (DIS3L), transcript variant 13, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	14-16	$475.30 $679.00
OHu82920	NM_001323946.1	Homo sapiens DIS3 like exosome 3'-5' exoribonuclease (DIS3L), transcript variant 12, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	10-12	$475.30 $679.00
OHu48094	NM_001323944.1	Homo sapiens DIS3 like exosome 3'-5' exoribonuclease (DIS3L), transcript variant 10, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	20	$559.30 $799.00
OHu09544	NM_133375.3	Homo sapiens DIS3 like exosome 3'-5' exoribonuclease (DIS3L), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$339.50-$475.30 $679.00
OHu82920	NM_001323941.1	Homo sapiens DIS3 like exosome 3'-5' exoribonuclease (DIS3L), transcript variant 8, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	10-12	$475.30 $679.00
Hide Old Accession Versions >>

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***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

DIS3L ( NM_001143688.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_001137160.1 Homo sapiens DIS3 like exosome 3'-5' exoribonuclease (DIS3L), transcript variant 1, mRNA.

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CloneID	OHu09540
Clone ID Related Accession (Same CDS sequence)	NM_001143688.3 , NM_001143688.2 , NM_001143688.1
Accession Version	NM_001143688.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 3165bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-09-24
Organism	Homo sapiens(human)
Product	DIS3-like exonuclease 1 isoform 1
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AC055855.9. On Nov 22, 2018 this sequence version replaced NM_001143688.2. Transcript Variant: This variant (1) encodes the longest isoform (1). Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. ##Evidence-Data-START## Transcript exon combination :: SRR1803611.129073.1, SRR1660807.228454.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000319212.9/ ENSP00000321711.4 RefSeq Select criteria :: based on conservation, expression, longest protein ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGCTGCAGA AGCGGGAGAA GGTGCTGCTG CTGAGGACCT TCCAGGGCCG CACGCTGCGG 
ATCGTGCGCG AGCACTACCT GCGGCCCTGC GTGCCCTGCC ACAGCCCGCT CTGCCCGCAG 
CCCGCCGCCT GCAGCCACGA TGGGAAACTC TTGTCTAGTG ATGTGACTCA TTACGTGATC 
CCAGACTGGA AAGTTGTTCA AGATTATCTT GAGATCCTTG AGTTTCCTGA GTTGAAGGGA 
ATTATTTTCA TGCAGACAGC TTGTCAAGCT GTGCAGCATC AAAGAGGCAG GAGACAGTAT 
AACAAACTGC GAAACCTGCT GAAGGATGCG CGTCATGATT GCATTCTCTT TGCTAATGAA 
TTCCAGCAAT GCTGCTATCT GCCACGGGAA AGAGGAGAGT CCATGGAGAA GTGGCAGACC 
AGGAGCATAT ACAACGCAGC TGTTTGGTAC TATCATCACT GCCAGGACAG GATGCCAATT 
GTTATGGTGA CAGAAGATGA AGAGGCAATT CAGCAGTATG GAAGTGAAAC AGAAGGAGTA 
TTCGTGATTA CTTTCAAGAA TTACCTGGAC AATTTCTGGC CTGATTTAAA AGCTGCCCAC 
GAGCTTTGTG ATTCTATCCT TCAGTCTCGA CGGGAGAGAG AGAATGAGAG TCAGGAGAGC 
CATGGGAAGG AGTACCCAGA ACATCTTCCC CTGGAAGTGT TAGAAGCTGG GATTAAATCT 
GGACGCTATA TCCAGGGAAT TCTGAATGTC AACAAACACA GAGCCCAAAT AGAAGCTTTT 
GTTCGACTTC AAGGAGCCAG CAGTAAAGAT TCAGATTTAG TCAGTGACAT CCTAATCCAC 
GGGATGAAGG CTCGAAACCG CTCAATTCAT GGAGATGTGG TAGTTGTGGA GCTGCTTCCT 
AAAAATGAAT GGAAAGGAAG AACCGTAGCC CTGTGTGAGA ATGACTGTGA CGACAAGGCT 
TCGGGCGAGT CCCCAAGTGA GCCCATGCCT ACAGGTCGAG TGGTGGGCAT ACTTCAGAAG 
AACTGGCGGG ATTATGTGGT GACATTTCCG TCCAAAGAAG AGGTCCAATC TCAGGGCAAA 
AATGCTCAGA AAATCCTGGT TACACCTTGG GATTACAGAA TTCCCAAAAT TCGAATTAGC 
ACTCAGCAAG CAGAAACCCT CCAGGACTTC AGGGTGGTCG TGCGCATCGA TTCCTGGGAG 
TCAACATCTG TGTATCCAAA TGGACATTTT GTGCGTGTTT TAGGAAGAAT CGGAGATCTG 
GAAGGGGAAA TTGCAACCAT CCTGGTGGAA AACAGTATTT CAGTTATTCC TTTCTCAGAA 
GCTCAGATGT GTGAGATGCC AGTAAACACA CCAGAAAGTC CCTGGAAGGT GAGTCCTGAA 
GAGGAACAAA AACGTAAAGA CTTGAGGAAA AGCCATCTCG TATTCAGCAT TGACCCCAAA 
GGTTGTGAAG ATGTGGATGA CACACTCTCA GTCAGAACCT TAAATAATGG CAACCTGGAA 
CTTGGGGTCC ACATCGCAGA TGTAACACAC TTTGTGGCAC CAAATTCTTA CATTGATATT 
GAAGCTAGAA CAAGGGCCAC CACTTATTAT CTAGCAGATC GTCGCTATGA CATGCTGCCT 
TCCGTCCTCA GTGCAGATTT GTGTTCCCTT CTGGGAGGCG TTGATAGGTA TGCTGTAAGC 
ATCATGTGGG AACTGGATAA AGCCTCTTAT GAAATTAAGA AAGTGTGGTA TGGCAGAACC 
ATTATTCGAT CAGCATACAA ACTGTTCTAT GAAGCAGCCC AAGAACTACT GGATGGAAAC 
TTAAGCGTTG TTGATGATAT TCCAGAATTC AAAGACTTGG ATGAGAAGAG CAGACAAGCC 
AAGCTGGAGG AGTTGGTGTG GGCAATTGGA AAGCTGACCG ACATAGCTCG CCATGTCAGA 
GCTAAACGAG ACGGATGTGG TGCCCTGGAA CTGGAAGGGG TAGAGGTTTG CGTACAGCTA 
GATGACAAAA AGAACATTCA CGACCTCATC CCCAAGCAGC CCCTGGAAGT CCACGAGACA 
GTGGCTGAAT GCATGATCCT GGCCAACCAC TGGGTCGCCA AAAAGATCTG GGAGAGCTTC 
CCTCATCAGG CCTTGCTGCG CCAGCACCCT CCTCCACACC AGGAGTTCTT TTCAGAACTC 
CGGGAATGTG CTAAAGCCAA AGGCTTCTTC ATAGATACAC GGTCCAATAA AACACTGGCT 
GATTCTCTGG ATAATGCGAA CGACCCCCAC GATCCCATTG TGAACAGGCT ACTGCGCTCC 
ATGGCCACGC AGGCCATGTC GAATGCTCTG TACTTCTCCA CCGGATCCTG TGCGGAGGAG 
GAGTTCCATC ATTACGGTCT TGCATTAGAT AAATATACCC ACTTTACTTC TCCAATAAGA 
AGATATTCAG ATATTGTAGT ACACCGCTTG TTAATGGCAG CCATTTCAAA AGATAAGAAA 
ATGGAAATTA AGGGAAATCT GTTCAGCAAC AAAGATCTTG AGGAATTATG CAGACATATC 
AACAACAGAA ACCAAGCAGC ACAGCATTCT CAGAAGCAGT CTACTGAGCT CTTCCAGTGC 
ATGTACTTCA AAGACAAAGA CCCTGCCACC GAGGAGCGTT GCATATCTGA CGGAGTTATT 
TATTCAATTA GAACAAATGG TGTGCTTCTA TTTATACCAA GGTTTGGGAT TAAAGGTGCT 
GCTTATCTAA AAAATAAAGA TGGTTTAGTC ATCTCATGTG GCCCAGATAG CTGTTCTGAA 
TGGAAACCAG GATCCCTTCA ACGATTTCAA AACAAAATTA CCTCTACTAC AACAGATGGG 
GAATCTGTTA CGTTCCATTT GTTTGACCAT GTAACCGTAA GAATATCCAT ACAGGCCTCA 
CGTTGCCATT CTGATACAAT CAGACTTGAA ATAATTAGTA ACAAACCATA CAAGATACCA 
AATACAGAAC TTATTCATCA GAGTTCCCCC TTGCTGAAGA GTGAGTTAGT GAAAGAAGTA 
ACTAAATCTG TGGAAGAAGC TCAGCTTGCC CAAGAAGTCA AAGTAAACAT CATTCAGGAG 
GAATATCAAG AATATCGCCA AACAAAGGGA AGGAGCCTAT ACACACTTCT AGAGGAGATA 
CGGGACCTAG CTCTCCTGGA TGTTTCAAAC AATTATGGAA TATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001137160.1
CDS	30..3194
Translation	MLQKREKVLLLRTFQGRTLRIVREHYLRPCVPCHSPLCPQPAACSHDGKLLSSDVTHYVIPDWKVVQDYLEILEFPELKGIIFMQTACQAVQHQRGRRQYNKLRNLLKDARHDCILFANEFQQCCYLPRERGESMEKWQTRSIYNAAVWYYHHCQDRMPIVMVTEDEEAIQQYGSETEGVFVITFKNYLDNFWPDLKAAHELCDSILQSRRERENESQESHGKEYPEHLPLEVLEAGIKSGRYIQGILNVNKHRAQIEAFVRLQGASSKDSDLVSDILIHGMKARNRSIHGDVVVVELLPKNEWKGRTVALCENDCDDKASGESPSEPMPTGRVVGILQKNWRDYVVTFPSKEEVQSQGKNAQKILVTPWDYRIPKIRISTQQAETLQDFRVVVRIDSWESTSVYPNGHFVRVLGRIGDLEGEIATILVENSISVIPFSEAQMCEMPVNTPESPWKVSPEEEQKRKDLRKSHLVFSIDPKGCEDVDDTLSVRTLNNGNLELGVHIADVTHFVAPNSYIDIEARTRATTYYLADRRYDMLPSVLSADLCSLLGGVDRYAVSIMWELDKASYEIKKVWYGRTIIRSAYKLFYEAAQELLDGNLSVVDDIPEFKDLDEKSRQAKLEELVWAIGKLTDIARHVRAKRDGCGALELEGVEVCVQLDDKKNIHDLIPKQPLEVHETVAECMILANHWVAKKIWESFPHQALLRQHPPPHQEFFSELRECAKAKGFFIDTRSNKTLADSLDNANDPHDPIVNRLLRSMATQAMSNALYFSTGSCAEEEFHHYGLALDKYTHFTSPIRRYSDIVVHRLLMAAISKDKKMEIKGNLFSNKDLEELCRHINNRNQAAQHSQKQSTELFQCMYFKDKDPATEERCISDGVIYSIRTNGVLLFIPRFGIKGAAYLKNKDGLVISCGPDSCSEWKPGSLQRFQNKITSTTTDGESVTFHLFDHVTVRISIQASRCHSDTIRLEIISNKPYKIPNTELIHQSSPLLKSELVKEVTKSVEEAQLAQEVKVNIIQEEYQEYRQTKGRSLYTLLEEIRDLALLDVSNNYGI

Target ORF information:

RefSeq Version	NM_001143688.3
Organism	Homo sapiens(human)
Definition	Homo sapiens DIS3 like exosome 3'-5' exoribonuclease (DIS3L), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001143688.3

ORF Insert Sequence:

ATGCTGCAGA AGCGGGAGAA GGTGCTGCTG CTGAGGACCT TCCAGGGCCG CACGCTGCGG 
ATCGTGCGCG AGCACTACCT GCGGCCCTGC GTGCCCTGCC ACAGCCCGCT CTGCCCGCAG 
CCCGCCGCCT GCAGCCACGA TGGGAAACTC TTGTCTAGTG ATGTGACTCA TTACGTGATC 
CCAGACTGGA AAGTTGTTCA AGATTATCTT GAGATCCTTG AGTTTCCTGA GTTGAAGGGA 
ATTATTTTCA TGCAGACAGC TTGTCAAGCT GTGCAGCATC AAAGAGGCAG GAGACAGTAT 
AACAAACTGC GAAACCTGCT GAAGGATGCG CGTCATGATT GCATTCTCTT TGCTAATGAA 
TTCCAGCAAT GCTGCTATCT GCCACGGGAA AGAGGAGAGT CCATGGAGAA GTGGCAGACC 
AGGAGCATAT ACAACGCAGC TGTTTGGTAC TATCATCACT GCCAGGACAG GATGCCAATT 
GTTATGGTGA CAGAAGATGA AGAGGCAATT CAGCAGTATG GAAGTGAAAC AGAAGGAGTA 
TTCGTGATTA CTTTCAAGAA TTACCTGGAC AATTTCTGGC CTGATTTAAA AGCTGCCCAC 
GAGCTTTGTG ATTCTATCCT TCAGTCTCGA CGGGAGAGAG AGAATGAGAG TCAGGAGAGC 
CATGGGAAGG AGTACCCAGA ACATCTTCCC CTGGAAGTGT TAGAAGCTGG GATTAAATCT 
GGACGCTATA TCCAGGGAAT TCTGAATGTC AACAAACACA GAGCCCAAAT AGAAGCTTTT 
GTTCGACTTC AAGGAGCCAG CAGTAAAGAT TCAGATTTAG TCAGTGACAT CCTAATCCAC 
GGGATGAAGG CTCGAAACCG CTCAATTCAT GGAGATGTGG TAGTTGTGGA GCTGCTTCCT 
AAAAATGAAT GGAAAGGAAG AACCGTAGCC CTGTGTGAGA ATGACTGTGA CGACAAGGCT 
TCGGGCGAGT CCCCAAGTGA GCCCATGCCT ACAGGTCGAG TGGTGGGCAT ACTTCAGAAG 
AACTGGCGGG ATTATGTGGT GACATTTCCG TCCAAAGAAG AGGTCCAATC TCAGGGCAAA 
AATGCTCAGA AAATCCTGGT TACACCTTGG GATTACAGAA TTCCCAAAAT TCGAATTAGC 
ACTCAGCAAG CAGAAACCCT CCAGGACTTC AGGGTGGTCG TGCGCATCGA TTCCTGGGAG 
TCAACATCTG TGTATCCAAA TGGACATTTT GTGCGTGTTT TAGGAAGAAT CGGAGATCTG 
GAAGGGGAAA TTGCAACCAT CCTGGTGGAA AACAGTATTT CAGTTATTCC TTTCTCAGAA 
GCTCAGATGT GTGAGATGCC AGTAAACACA CCAGAAAGTC CCTGGAAGGT GAGTCCTGAA 
GAGGAACAAA AACGTAAAGA CTTGAGGAAA AGCCATCTCG TATTCAGCAT TGACCCCAAA 
GGTTGTGAAG ATGTGGATGA CACACTCTCA GTCAGAACCT TAAATAATGG CAACCTGGAA 
CTTGGGGTCC ACATCGCAGA TGTAACACAC TTTGTGGCAC CAAATTCTTA CATTGATATT 
GAAGCTAGAA CAAGGGCCAC CACTTATTAT CTAGCAGATC GTCGCTATGA CATGCTGCCT 
TCCGTCCTCA GTGCAGATTT GTGTTCCCTT CTGGGAGGCG TTGATAGGTA TGCTGTAAGC 
ATCATGTGGG AACTGGATAA AGCCTCTTAT GAAATTAAGA AAGTGTGGTA TGGCAGAACC 
ATTATTCGAT CAGCATACAA ACTGTTCTAT GAAGCAGCCC AAGAACTACT GGATGGAAAC 
TTAAGCGTTG TTGATGATAT TCCAGAATTC AAAGACTTGG ATGAGAAGAG CAGACAAGCC 
AAGCTGGAGG AGTTGGTGTG GGCAATTGGA AAGCTGACCG ACATAGCTCG CCATGTCAGA 
GCTAAACGAG ACGGATGTGG TGCCCTGGAA CTGGAAGGGG TAGAGGTTTG CGTACAGCTA 
GATGACAAAA AGAACATTCA CGACCTCATC CCCAAGCAGC CCCTGGAAGT CCACGAGACA 
GTGGCTGAAT GCATGATCCT GGCCAACCAC TGGGTCGCCA AAAAGATCTG GGAGAGCTTC 
CCTCATCAGG CCTTGCTGCG CCAGCACCCT CCTCCACACC AGGAGTTCTT TTCAGAACTC 
CGGGAATGTG CTAAAGCCAA AGGCTTCTTC ATAGATACAC GGTCCAATAA AACACTGGCT 
GATTCTCTGG ATAATGCGAA CGACCCCCAC GATCCCATTG TGAACAGGCT ACTGCGCTCC 
ATGGCCACGC AGGCCATGTC GAATGCTCTG TACTTCTCCA CCGGATCCTG TGCGGAGGAG 
GAGTTCCATC ATTACGGTCT TGCATTAGAT AAATATACCC ACTTTACTTC TCCAATAAGA 
AGATATTCAG ATATTGTAGT ACACCGCTTG TTAATGGCAG CCATTTCAAA AGATAAGAAA 
ATGGAAATTA AGGGAAATCT GTTCAGCAAC AAAGATCTTG AGGAATTATG CAGACATATC 
AACAACAGAA ACCAAGCAGC ACAGCATTCT CAGAAGCAGT CTACTGAGCT CTTCCAGTGC 
ATGTACTTCA AAGACAAAGA CCCTGCCACC GAGGAGCGTT GCATATCTGA CGGAGTTATT 
TATTCAATTA GAACAAATGG TGTGCTTCTA TTTATACCAA GGTTTGGGAT TAAAGGTGCT 
GCTTATCTAA AAAATAAAGA TGGTTTAGTC ATCTCATGTG GCCCAGATAG CTGTTCTGAA 
TGGAAACCAG GATCCCTTCA ACGATTTCAA AACAAAATTA CCTCTACTAC AACAGATGGG 
GAATCTGTTA CGTTCCATTT GTTTGACCAT GTAACCGTAA GAATATCCAT ACAGGCCTCA 
CGTTGCCATT CTGATACAAT CAGACTTGAA ATAATTAGTA ACAAACCATA CAAGATACCA 
AATACAGAAC TTATTCATCA GAGTTCCCCC TTGCTGAAGA GTGAGTTAGT GAAAGAAGTA 
ACTAAATCTG TGGAAGAAGC TCAGCTTGCC CAAGAAGTCA AAGTAAACAT CATTCAGGAG 
GAATATCAAG AATATCGCCA AACAAAGGGA AGGAGCCTAT ACACACTTCT AGAGGAGATA 
CGGGACCTAG CTCTCCTGGA TGTTTCAAAC AATTATGGAA TATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

DIS3L ( NM_001143688.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_001137160.1 Homo sapiens DIS3 like exosome 3'-5' exoribonuclease (DIS3L), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu09540
Clone ID Related Accession (Same CDS sequence)	NM_001143688.3 , NM_001143688.2 , NM_001143688.1
Accession Version	NM_001143688.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 3165bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-09-09
Organism	Homo sapiens(human)
Product	DIS3-like exonuclease 1 isoform 1
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AC055855.9. On Apr 23, 2016 this sequence version replaced NM_001143688.1. Transcript Variant: This variant (1) encodes the longest isoform (1). Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. ##Evidence-Data-START## RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END##

ATGCTGCAGA AGCGGGAGAA GGTGCTGCTG CTGAGGACCT TCCAGGGCCG CACGCTGCGG 
ATCGTGCGCG AGCACTACCT GCGGCCCTGC GTGCCCTGCC ACAGCCCGCT CTGCCCGCAG 
CCCGCCGCCT GCAGCCACGA TGGGAAACTC TTGTCTAGTG ATGTGACTCA TTACGTGATC 
CCAGACTGGA AAGTTGTTCA AGATTATCTT GAGATCCTTG AGTTTCCTGA GTTGAAGGGA 
ATTATTTTCA TGCAGACAGC TTGTCAAGCT GTGCAGCATC AAAGAGGCAG GAGACAGTAT 
AACAAACTGC GAAACCTGCT GAAGGATGCG CGTCATGATT GCATTCTCTT TGCTAATGAA 
TTCCAGCAAT GCTGCTATCT GCCACGGGAA AGAGGAGAGT CCATGGAGAA GTGGCAGACC 
AGGAGCATAT ACAACGCAGC TGTTTGGTAC TATCATCACT GCCAGGACAG GATGCCAATT 
GTTATGGTGA CAGAAGATGA AGAGGCAATT CAGCAGTATG GAAGTGAAAC AGAAGGAGTA 
TTCGTGATTA CTTTCAAGAA TTACCTGGAC AATTTCTGGC CTGATTTAAA AGCTGCCCAC 
GAGCTTTGTG ATTCTATCCT TCAGTCTCGA CGGGAGAGAG AGAATGAGAG TCAGGAGAGC 
CATGGGAAGG AGTACCCAGA ACATCTTCCC CTGGAAGTGT TAGAAGCTGG GATTAAATCT 
GGACGCTATA TCCAGGGAAT TCTGAATGTC AACAAACACA GAGCCCAAAT AGAAGCTTTT 
GTTCGACTTC AAGGAGCCAG CAGTAAAGAT TCAGATTTAG TCAGTGACAT CCTAATCCAC 
GGGATGAAGG CTCGAAACCG CTCAATTCAT GGAGATGTGG TAGTTGTGGA GCTGCTTCCT 
AAAAATGAAT GGAAAGGAAG AACCGTAGCC CTGTGTGAGA ATGACTGTGA CGACAAGGCT 
TCGGGCGAGT CCCCAAGTGA GCCCATGCCT ACAGGTCGAG TGGTGGGCAT ACTTCAGAAG 
AACTGGCGGG ATTATGTGGT GACATTTCCG TCCAAAGAAG AGGTCCAATC TCAGGGCAAA 
AATGCTCAGA AAATCCTGGT TACACCTTGG GATTACAGAA TTCCCAAAAT TCGAATTAGC 
ACTCAGCAAG CAGAAACCCT CCAGGACTTC AGGGTGGTCG TGCGCATCGA TTCCTGGGAG 
TCAACATCTG TGTATCCAAA TGGACATTTT GTGCGTGTTT TAGGAAGAAT CGGAGATCTG 
GAAGGGGAAA TTGCAACCAT CCTGGTGGAA AACAGTATTT CAGTTATTCC TTTCTCAGAA 
GCTCAGATGT GTGAGATGCC AGTAAACACA CCAGAAAGTC CCTGGAAGGT GAGTCCTGAA 
GAGGAACAAA AACGTAAAGA CTTGAGGAAA AGCCATCTCG TATTCAGCAT TGACCCCAAA 
GGTTGTGAAG ATGTGGATGA CACACTCTCA GTCAGAACCT TAAATAATGG CAACCTGGAA 
CTTGGGGTCC ACATCGCAGA TGTAACACAC TTTGTGGCAC CAAATTCTTA CATTGATATT 
GAAGCTAGAA CAAGGGCCAC CACTTATTAT CTAGCAGATC GTCGCTATGA CATGCTGCCT 
TCCGTCCTCA GTGCAGATTT GTGTTCCCTT CTGGGAGGCG TTGATAGGTA TGCTGTAAGC 
ATCATGTGGG AACTGGATAA AGCCTCTTAT GAAATTAAGA AAGTGTGGTA TGGCAGAACC 
ATTATTCGAT CAGCATACAA ACTGTTCTAT GAAGCAGCCC AAGAACTACT GGATGGAAAC 
TTAAGCGTTG TTGATGATAT TCCAGAATTC AAAGACTTGG ATGAGAAGAG CAGACAAGCC 
AAGCTGGAGG AGTTGGTGTG GGCAATTGGA AAGCTGACCG ACATAGCTCG CCATGTCAGA 
GCTAAACGAG ACGGATGTGG TGCCCTGGAA CTGGAAGGGG TAGAGGTTTG CGTACAGCTA 
GATGACAAAA AGAACATTCA CGACCTCATC CCCAAGCAGC CCCTGGAAGT CCACGAGACA 
GTGGCTGAAT GCATGATCCT GGCCAACCAC TGGGTCGCCA AAAAGATCTG GGAGAGCTTC 
CCTCATCAGG CCTTGCTGCG CCAGCACCCT CCTCCACACC AGGAGTTCTT TTCAGAACTC 
CGGGAATGTG CTAAAGCCAA AGGCTTCTTC ATAGATACAC GGTCCAATAA AACACTGGCT 
GATTCTCTGG ATAATGCGAA CGACCCCCAC GATCCCATTG TGAACAGGCT ACTGCGCTCC 
ATGGCCACGC AGGCCATGTC GAATGCTCTG TACTTCTCCA CCGGATCCTG TGCGGAGGAG 
GAGTTCCATC ATTACGGTCT TGCATTAGAT AAATATACCC ACTTTACTTC TCCAATAAGA 
AGATATTCAG ATATTGTAGT ACACCGCTTG TTAATGGCAG CCATTTCAAA AGATAAGAAA 
ATGGAAATTA AGGGAAATCT GTTCAGCAAC AAAGATCTTG AGGAATTATG CAGACATATC 
AACAACAGAA ACCAAGCAGC ACAGCATTCT CAGAAGCAGT CTACTGAGCT CTTCCAGTGC 
ATGTACTTCA AAGACAAAGA CCCTGCCACC GAGGAGCGTT GCATATCTGA CGGAGTTATT 
TATTCAATTA GAACAAATGG TGTGCTTCTA TTTATACCAA GGTTTGGGAT TAAAGGTGCT 
GCTTATCTAA AAAATAAAGA TGGTTTAGTC ATCTCATGTG GCCCAGATAG CTGTTCTGAA 
TGGAAACCAG GATCCCTTCA ACGATTTCAA AACAAAATTA CCTCTACTAC AACAGATGGG 
GAATCTGTTA CGTTCCATTT GTTTGACCAT GTAACCGTAA GAATATCCAT ACAGGCCTCA 
CGTTGCCATT CTGATACAAT CAGACTTGAA ATAATTAGTA ACAAACCATA CAAGATACCA 
AATACAGAAC TTATTCATCA GAGTTCCCCC TTGCTGAAGA GTGAGTTAGT GAAAGAAGTA 
ACTAAATCTG TGGAAGAAGC TCAGCTTGCC CAAGAAGTCA AAGTAAACAT CATTCAGGAG 
GAATATCAAG AATATCGCCA AACAAAGGGA AGGAGCCTAT ACACACTTCT AGAGGAGATA 
CGGGACCTAG CTCTCCTGGA TGTTTCAAAC AATTATGGAA TATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001137160.1
CDS	23..3187
Translation	MLQKREKVLLLRTFQGRTLRIVREHYLRPCVPCHSPLCPQPAACSHDGKLLSSDVTHYVIPDWKVVQDYLEILEFPELKGIIFMQTACQAVQHQRGRRQYNKLRNLLKDARHDCILFANEFQQCCYLPRERGESMEKWQTRSIYNAAVWYYHHCQDRMPIVMVTEDEEAIQQYGSETEGVFVITFKNYLDNFWPDLKAAHELCDSILQSRRERENESQESHGKEYPEHLPLEVLEAGIKSGRYIQGILNVNKHRAQIEAFVRLQGASSKDSDLVSDILIHGMKARNRSIHGDVVVVELLPKNEWKGRTVALCENDCDDKASGESPSEPMPTGRVVGILQKNWRDYVVTFPSKEEVQSQGKNAQKILVTPWDYRIPKIRISTQQAETLQDFRVVVRIDSWESTSVYPNGHFVRVLGRIGDLEGEIATILVENSISVIPFSEAQMCEMPVNTPESPWKVSPEEEQKRKDLRKSHLVFSIDPKGCEDVDDTLSVRTLNNGNLELGVHIADVTHFVAPNSYIDIEARTRATTYYLADRRYDMLPSVLSADLCSLLGGVDRYAVSIMWELDKASYEIKKVWYGRTIIRSAYKLFYEAAQELLDGNLSVVDDIPEFKDLDEKSRQAKLEELVWAIGKLTDIARHVRAKRDGCGALELEGVEVCVQLDDKKNIHDLIPKQPLEVHETVAECMILANHWVAKKIWESFPHQALLRQHPPPHQEFFSELRECAKAKGFFIDTRSNKTLADSLDNANDPHDPIVNRLLRSMATQAMSNALYFSTGSCAEEEFHHYGLALDKYTHFTSPIRRYSDIVVHRLLMAAISKDKKMEIKGNLFSNKDLEELCRHINNRNQAAQHSQKQSTELFQCMYFKDKDPATEERCISDGVIYSIRTNGVLLFIPRFGIKGAAYLKNKDGLVISCGPDSCSEWKPGSLQRFQNKITSTTTDGESVTFHLFDHVTVRISIQASRCHSDTIRLEIISNKPYKIPNTELIHQSSPLLKSELVKEVTKSVEEAQLAQEVKVNIIQEEYQEYRQTKGRSLYTLLEEIRDLALLDVSNNYGI

Target ORF information:

RefSeq Version	NM_001143688.2
Organism	Homo sapiens(human)
Definition	Homo sapiens DIS3 like exosome 3'-5' exoribonuclease (DIS3L), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001143688.2

ORF Insert Sequence:

ATGCTGCAGA AGCGGGAGAA GGTGCTGCTG CTGAGGACCT TCCAGGGCCG CACGCTGCGG 
ATCGTGCGCG AGCACTACCT GCGGCCCTGC GTGCCCTGCC ACAGCCCGCT CTGCCCGCAG 
CCCGCCGCCT GCAGCCACGA TGGGAAACTC TTGTCTAGTG ATGTGACTCA TTACGTGATC 
CCAGACTGGA AAGTTGTTCA AGATTATCTT GAGATCCTTG AGTTTCCTGA GTTGAAGGGA 
ATTATTTTCA TGCAGACAGC TTGTCAAGCT GTGCAGCATC AAAGAGGCAG GAGACAGTAT 
AACAAACTGC GAAACCTGCT GAAGGATGCG CGTCATGATT GCATTCTCTT TGCTAATGAA 
TTCCAGCAAT GCTGCTATCT GCCACGGGAA AGAGGAGAGT CCATGGAGAA GTGGCAGACC 
AGGAGCATAT ACAACGCAGC TGTTTGGTAC TATCATCACT GCCAGGACAG GATGCCAATT 
GTTATGGTGA CAGAAGATGA AGAGGCAATT CAGCAGTATG GAAGTGAAAC AGAAGGAGTA 
TTCGTGATTA CTTTCAAGAA TTACCTGGAC AATTTCTGGC CTGATTTAAA AGCTGCCCAC 
GAGCTTTGTG ATTCTATCCT TCAGTCTCGA CGGGAGAGAG AGAATGAGAG TCAGGAGAGC 
CATGGGAAGG AGTACCCAGA ACATCTTCCC CTGGAAGTGT TAGAAGCTGG GATTAAATCT 
GGACGCTATA TCCAGGGAAT TCTGAATGTC AACAAACACA GAGCCCAAAT AGAAGCTTTT 
GTTCGACTTC AAGGAGCCAG CAGTAAAGAT TCAGATTTAG TCAGTGACAT CCTAATCCAC 
GGGATGAAGG CTCGAAACCG CTCAATTCAT GGAGATGTGG TAGTTGTGGA GCTGCTTCCT 
AAAAATGAAT GGAAAGGAAG AACCGTAGCC CTGTGTGAGA ATGACTGTGA CGACAAGGCT 
TCGGGCGAGT CCCCAAGTGA GCCCATGCCT ACAGGTCGAG TGGTGGGCAT ACTTCAGAAG 
AACTGGCGGG ATTATGTGGT GACATTTCCG TCCAAAGAAG AGGTCCAATC TCAGGGCAAA 
AATGCTCAGA AAATCCTGGT TACACCTTGG GATTACAGAA TTCCCAAAAT TCGAATTAGC 
ACTCAGCAAG CAGAAACCCT CCAGGACTTC AGGGTGGTCG TGCGCATCGA TTCCTGGGAG 
TCAACATCTG TGTATCCAAA TGGACATTTT GTGCGTGTTT TAGGAAGAAT CGGAGATCTG 
GAAGGGGAAA TTGCAACCAT CCTGGTGGAA AACAGTATTT CAGTTATTCC TTTCTCAGAA 
GCTCAGATGT GTGAGATGCC AGTAAACACA CCAGAAAGTC CCTGGAAGGT GAGTCCTGAA 
GAGGAACAAA AACGTAAAGA CTTGAGGAAA AGCCATCTCG TATTCAGCAT TGACCCCAAA 
GGTTGTGAAG ATGTGGATGA CACACTCTCA GTCAGAACCT TAAATAATGG CAACCTGGAA 
CTTGGGGTCC ACATCGCAGA TGTAACACAC TTTGTGGCAC CAAATTCTTA CATTGATATT 
GAAGCTAGAA CAAGGGCCAC CACTTATTAT CTAGCAGATC GTCGCTATGA CATGCTGCCT 
TCCGTCCTCA GTGCAGATTT GTGTTCCCTT CTGGGAGGCG TTGATAGGTA TGCTGTAAGC 
ATCATGTGGG AACTGGATAA AGCCTCTTAT GAAATTAAGA AAGTGTGGTA TGGCAGAACC 
ATTATTCGAT CAGCATACAA ACTGTTCTAT GAAGCAGCCC AAGAACTACT GGATGGAAAC 
TTAAGCGTTG TTGATGATAT TCCAGAATTC AAAGACTTGG ATGAGAAGAG CAGACAAGCC 
AAGCTGGAGG AGTTGGTGTG GGCAATTGGA AAGCTGACCG ACATAGCTCG CCATGTCAGA 
GCTAAACGAG ACGGATGTGG TGCCCTGGAA CTGGAAGGGG TAGAGGTTTG CGTACAGCTA 
GATGACAAAA AGAACATTCA CGACCTCATC CCCAAGCAGC CCCTGGAAGT CCACGAGACA 
GTGGCTGAAT GCATGATCCT GGCCAACCAC TGGGTCGCCA AAAAGATCTG GGAGAGCTTC 
CCTCATCAGG CCTTGCTGCG CCAGCACCCT CCTCCACACC AGGAGTTCTT TTCAGAACTC 
CGGGAATGTG CTAAAGCCAA AGGCTTCTTC ATAGATACAC GGTCCAATAA AACACTGGCT 
GATTCTCTGG ATAATGCGAA CGACCCCCAC GATCCCATTG TGAACAGGCT ACTGCGCTCC 
ATGGCCACGC AGGCCATGTC GAATGCTCTG TACTTCTCCA CCGGATCCTG TGCGGAGGAG 
GAGTTCCATC ATTACGGTCT TGCATTAGAT AAATATACCC ACTTTACTTC TCCAATAAGA 
AGATATTCAG ATATTGTAGT ACACCGCTTG TTAATGGCAG CCATTTCAAA AGATAAGAAA 
ATGGAAATTA AGGGAAATCT GTTCAGCAAC AAAGATCTTG AGGAATTATG CAGACATATC 
AACAACAGAA ACCAAGCAGC ACAGCATTCT CAGAAGCAGT CTACTGAGCT CTTCCAGTGC 
ATGTACTTCA AAGACAAAGA CCCTGCCACC GAGGAGCGTT GCATATCTGA CGGAGTTATT 
TATTCAATTA GAACAAATGG TGTGCTTCTA TTTATACCAA GGTTTGGGAT TAAAGGTGCT 
GCTTATCTAA AAAATAAAGA TGGTTTAGTC ATCTCATGTG GCCCAGATAG CTGTTCTGAA 
TGGAAACCAG GATCCCTTCA ACGATTTCAA AACAAAATTA CCTCTACTAC AACAGATGGG 
GAATCTGTTA CGTTCCATTT GTTTGACCAT GTAACCGTAA GAATATCCAT ACAGGCCTCA 
CGTTGCCATT CTGATACAAT CAGACTTGAA ATAATTAGTA ACAAACCATA CAAGATACCA 
AATACAGAAC TTATTCATCA GAGTTCCCCC TTGCTGAAGA GTGAGTTAGT GAAAGAAGTA 
ACTAAATCTG TGGAAGAAGC TCAGCTTGCC CAAGAAGTCA AAGTAAACAT CATTCAGGAG 
GAATATCAAG AATATCGCCA AACAAAGGGA AGGAGCCTAT ACACACTTCT AGAGGAGATA 
CGGGACCTAG CTCTCCTGGA TGTTTCAAAC AATTATGGAA TATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

DIS3L ( NM_001143688.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001137160.1 Homo sapiens DIS3 like exosome 3'-5' exoribonuclease (DIS3L), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu09540
Clone ID Related Accession (Same CDS sequence)	NM_001143688.3 , NM_001143688.2 , NM_001143688.1
Accession Version	NM_001143688.1	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 3165bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2015-03-14
Organism	Homo sapiens(Human)
Product	DIS3-like exonuclease 1 isoform 1
Comment

ATGCTGCAGA AGCGGGAGAA GGTGCTGCTG CTGAGGACCT TCCAGGGCCG CACGCTGCGG 
ATCGTGCGCG AGCACTACCT GCGGCCCTGC GTGCCCTGCC ACAGCCCGCT CTGCCCGCAG 
CCCGCCGCCT GCAGCCACGA TGGGAAACTC TTGTCTAGTG ATGTGACTCA TTACGTGATC 
CCAGACTGGA AAGTTGTTCA AGATTATCTT GAGATCCTTG AGTTTCCTGA GTTGAAGGGA 
ATTATTTTCA TGCAGACAGC TTGTCAAGCT GTGCAGCATC AAAGAGGCAG GAGACAGTAT 
AACAAACTGC GAAACCTGCT GAAGGATGCG CGTCATGATT GCATTCTCTT TGCTAATGAA 
TTCCAGCAAT GCTGCTATCT GCCACGGGAA AGAGGAGAGT CCATGGAGAA GTGGCAGACC 
AGGAGCATAT ACAACGCAGC TGTTTGGTAC TATCATCACT GCCAGGACAG GATGCCAATT 
GTTATGGTGA CAGAAGATGA AGAGGCAATT CAGCAGTATG GAAGTGAAAC AGAAGGAGTA 
TTCGTGATTA CTTTCAAGAA TTACCTGGAC AATTTCTGGC CTGATTTAAA AGCTGCCCAC 
GAGCTTTGTG ATTCTATCCT TCAGTCTCGA CGGGAGAGAG AGAATGAGAG TCAGGAGAGC 
CATGGGAAGG AGTACCCAGA ACATCTTCCC CTGGAAGTGT TAGAAGCTGG GATTAAATCT 
GGACGCTATA TCCAGGGAAT TCTGAATGTC AACAAACACA GAGCCCAAAT AGAAGCTTTT 
GTTCGACTTC AAGGAGCCAG CAGTAAAGAT TCAGATTTAG TCAGTGACAT CCTAATCCAC 
GGGATGAAGG CTCGAAACCG CTCAATTCAT GGAGATGTGG TAGTTGTGGA GCTGCTTCCT 
AAAAATGAAT GGAAAGGAAG AACCGTAGCC CTGTGTGAGA ATGACTGTGA CGACAAGGCT 
TCGGGCGAGT CCCCAAGTGA GCCCATGCCT ACAGGTCGAG TGGTGGGCAT ACTTCAGAAG 
AACTGGCGGG ATTATGTGGT GACATTTCCG TCCAAAGAAG AGGTCCAATC TCAGGGCAAA 
AATGCTCAGA AAATCCTGGT TACACCTTGG GATTACAGAA TTCCCAAAAT TCGAATTAGC 
ACTCAGCAAG CAGAAACCCT CCAGGACTTC AGGGTGGTCG TGCGCATCGA TTCCTGGGAG 
TCAACATCTG TGTATCCAAA TGGACATTTT GTGCGTGTTT TAGGAAGAAT CGGAGATCTG 
GAAGGGGAAA TTGCAACCAT CCTGGTGGAA AACAGTATTT CAGTTATTCC TTTCTCAGAA 
GCTCAGATGT GTGAGATGCC AGTAAACACA CCAGAAAGTC CCTGGAAGGT GAGTCCTGAA 
GAGGAACAAA AACGTAAAGA CTTGAGGAAA AGCCATCTCG TATTCAGCAT TGACCCCAAA 
GGTTGTGAAG ATGTGGATGA CACACTCTCA GTCAGAACCT TAAATAATGG CAACCTGGAA 
CTTGGGGTCC ACATCGCAGA TGTAACACAC TTTGTGGCAC CAAATTCTTA CATTGATATT 
GAAGCTAGAA CAAGGGCCAC CACTTATTAT CTAGCAGATC GTCGCTATGA CATGCTGCCT 
TCCGTCCTCA GTGCAGATTT GTGTTCCCTT CTGGGAGGCG TTGATAGGTA TGCTGTAAGC 
ATCATGTGGG AACTGGATAA AGCCTCTTAT GAAATTAAGA AAGTGTGGTA TGGCAGAACC 
ATTATTCGAT CAGCATACAA ACTGTTCTAT GAAGCAGCCC AAGAACTACT GGATGGAAAC 
TTAAGCGTTG TTGATGATAT TCCAGAATTC AAAGACTTGG ATGAGAAGAG CAGACAAGCC 
AAGCTGGAGG AGTTGGTGTG GGCAATTGGA AAGCTGACCG ACATAGCTCG CCATGTCAGA 
GCTAAACGAG ACGGATGTGG TGCCCTGGAA CTGGAAGGGG TAGAGGTTTG CGTACAGCTA 
GATGACAAAA AGAACATTCA CGACCTCATC CCCAAGCAGC CCCTGGAAGT CCACGAGACA 
GTGGCTGAAT GCATGATCCT GGCCAACCAC TGGGTCGCCA AAAAGATCTG GGAGAGCTTC 
CCTCATCAGG CCTTGCTGCG CCAGCACCCT CCTCCACACC AGGAGTTCTT TTCAGAACTC 
CGGGAATGTG CTAAAGCCAA AGGCTTCTTC ATAGATACAC GGTCCAATAA AACACTGGCT 
GATTCTCTGG ATAATGCGAA CGACCCCCAC GATCCCATTG TGAACAGGCT ACTGCGCTCC 
ATGGCCACGC AGGCCATGTC GAATGCTCTG TACTTCTCCA CCGGATCCTG TGCGGAGGAG 
GAGTTCCATC ATTACGGTCT TGCATTAGAT AAATATACCC ACTTTACTTC TCCAATAAGA 
AGATATTCAG ATATTGTAGT ACACCGCTTG TTAATGGCAG CCATTTCAAA AGATAAGAAA 
ATGGAAATTA AGGGAAATCT GTTCAGCAAC AAAGATCTTG AGGAATTATG CAGACATATC 
AACAACAGAA ACCAAGCAGC ACAGCATTCT CAGAAGCAGT CTACTGAGCT CTTCCAGTGC 
ATGTACTTCA AAGACAAAGA CCCTGCCACC GAGGAGCGTT GCATATCTGA CGGAGTTATT 
TATTCAATTA GAACAAATGG TGTGCTTCTA TTTATACCAA GGTTTGGGAT TAAAGGTGCT 
GCTTATCTAA AAAATAAAGA TGGTTTAGTC ATCTCATGTG GCCCAGATAG CTGTTCTGAA 
TGGAAACCAG GATCCCTTCA ACGATTTCAA AACAAAATTA CCTCTACTAC AACAGATGGG 
GAATCTGTTA CGTTCCATTT GTTTGACCAT GTAACCGTAA GAATATCCAT ACAGGCCTCA 
CGTTGCCATT CTGATACAAT CAGACTTGAA ATAATTAGTA ACAAACCATA CAAGATACCA 
AATACAGAAC TTATTCATCA GAGTTCCCCC TTGCTGAAGA GTGAGTTAGT GAAAGAAGTA 
ACTAAATCTG TGGAAGAAGC TCAGCTTGCC CAAGAAGTCA AAGTAAACAT CATTCAGGAG 
GAATATCAAG AATATCGCCA AACAAAGGGA AGGAGCCTAT ACACACTTCT AGAGGAGATA 
CGGGACCTAG CTCTCCTGGA TGTTTCAAAC AATTATGGAA TATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq

NP_001137160.1

Translation

MLQKREKVLLLRTFQGRTLRIVREHYLRPCVPCHSPLCPQPAACSHDGKLLSSDVTHYVIPDWKVVQDYLEILEFPELKGIIFMQTACQAVQHQRGRRQYNKLRNLLKDARHDCILFANEFQQCCYLPRERGESMEKWQTRSIYNAAVWYYHHCQDRMPIVMVTEDEEAIQQYGSETEGVFVITFKNYLDNFWPDLKAAHELCDSILQSRRERENESQESHGKEYPEHLPLEVLEAGIKSGRYIQGILNVNKHRAQIEAFVRLQGASSKDSDLVSDILIHGMKARNRSIHGDVVVVELLPKNEWKGRTVALCENDCDDKASGESPSEPMPTGRVVGILQKNWRDYVVTFPSKEEVQSQGKNAQKILVTPWDYRIPKIRISTQQAETLQDFRVVVRIDSWESTSVYPNGHFVRVLGRIGDLEGEIATILVENSISVIPFSEAQMCEMPVNTPESPWKVSPEEEQKRKDLRKSHLVFSIDPKGCEDVDDTLSVRTLNNGNLELGVHIADVTHFVAPNSYIDIEARTRATTYYLADRRYDMLPSVLSADLCSLLGGVDRYAVSIMWELDKASYEIKKVWYGRTIIRSAYKLFYEAAQELLDGNLSVVDDIPEFKDLDEKSRQAKLEELVWAIGKLTDIARHVRAKRDGCGALELEGVEVCVQLDDKKNIHDLIPKQPLEVHETVAECMILANHWVAKKIWESFPHQALLRQHPPPHQEFFSELRECAKAKGFFIDTRSNKTLADSLDNANDPHDPIVNRLLRSMATQAMSNALYFSTGSCAEEEFHHYGLALDKYTHFTSPIRRYSDIVVHRLLMAAISKDKKMEIKGNLFSNKDLEELCRHINNRNQAAQHSQKQSTELFQCMYFKDKDPATEERCISDGVIYSIRTNGVLLFIPRFGIKGAAYLKNKDGLVISCGPDSCSEWKPGSLQRFQNKITSTTTDGESVTFHLFDHVTVRISIQASRCHSDTIRLEIISNKPYKIPNTELIHQSSPLLKSELVKEVTKSVEEAQLAQEVKVNIIQEEYQEYRQTKGRSLYTLLEEIRDLALLDVSNNYGI

Target ORF information:

RefSeq Version	NM_001143688.1
Organism	Homo sapiens(Human)
Definition	Homo sapiens DIS3 like exosome 3'-5' exoribonuclease (DIS3L), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001143688.1

ORF Insert Sequence:

ATGCTGCAGA AGCGGGAGAA GGTGCTGCTG CTGAGGACCT TCCAGGGCCG CACGCTGCGG 
ATCGTGCGCG AGCACTACCT GCGGCCCTGC GTGCCCTGCC ACAGCCCGCT CTGCCCGCAG 
CCCGCCGCCT GCAGCCACGA TGGGAAACTC TTGTCTAGTG ATGTGACTCA TTACGTGATC 
CCAGACTGGA AAGTTGTTCA AGATTATCTT GAGATCCTTG AGTTTCCTGA GTTGAAGGGA 
ATTATTTTCA TGCAGACAGC TTGTCAAGCT GTGCAGCATC AAAGAGGCAG GAGACAGTAT 
AACAAACTGC GAAACCTGCT GAAGGATGCG CGTCATGATT GCATTCTCTT TGCTAATGAA 
TTCCAGCAAT GCTGCTATCT GCCACGGGAA AGAGGAGAGT CCATGGAGAA GTGGCAGACC 
AGGAGCATAT ACAACGCAGC TGTTTGGTAC TATCATCACT GCCAGGACAG GATGCCAATT 
GTTATGGTGA CAGAAGATGA AGAGGCAATT CAGCAGTATG GAAGTGAAAC AGAAGGAGTA 
TTCGTGATTA CTTTCAAGAA TTACCTGGAC AATTTCTGGC CTGATTTAAA AGCTGCCCAC 
GAGCTTTGTG ATTCTATCCT TCAGTCTCGA CGGGAGAGAG AGAATGAGAG TCAGGAGAGC 
CATGGGAAGG AGTACCCAGA ACATCTTCCC CTGGAAGTGT TAGAAGCTGG GATTAAATCT 
GGACGCTATA TCCAGGGAAT TCTGAATGTC AACAAACACA GAGCCCAAAT AGAAGCTTTT 
GTTCGACTTC AAGGAGCCAG CAGTAAAGAT TCAGATTTAG TCAGTGACAT CCTAATCCAC 
GGGATGAAGG CTCGAAACCG CTCAATTCAT GGAGATGTGG TAGTTGTGGA GCTGCTTCCT 
AAAAATGAAT GGAAAGGAAG AACCGTAGCC CTGTGTGAGA ATGACTGTGA CGACAAGGCT 
TCGGGCGAGT CCCCAAGTGA GCCCATGCCT ACAGGTCGAG TGGTGGGCAT ACTTCAGAAG 
AACTGGCGGG ATTATGTGGT GACATTTCCG TCCAAAGAAG AGGTCCAATC TCAGGGCAAA 
AATGCTCAGA AAATCCTGGT TACACCTTGG GATTACAGAA TTCCCAAAAT TCGAATTAGC 
ACTCAGCAAG CAGAAACCCT CCAGGACTTC AGGGTGGTCG TGCGCATCGA TTCCTGGGAG 
TCAACATCTG TGTATCCAAA TGGACATTTT GTGCGTGTTT TAGGAAGAAT CGGAGATCTG 
GAAGGGGAAA TTGCAACCAT CCTGGTGGAA AACAGTATTT CAGTTATTCC TTTCTCAGAA 
GCTCAGATGT GTGAGATGCC AGTAAACACA CCAGAAAGTC CCTGGAAGGT GAGTCCTGAA 
GAGGAACAAA AACGTAAAGA CTTGAGGAAA AGCCATCTCG TATTCAGCAT TGACCCCAAA 
GGTTGTGAAG ATGTGGATGA CACACTCTCA GTCAGAACCT TAAATAATGG CAACCTGGAA 
CTTGGGGTCC ACATCGCAGA TGTAACACAC TTTGTGGCAC CAAATTCTTA CATTGATATT 
GAAGCTAGAA CAAGGGCCAC CACTTATTAT CTAGCAGATC GTCGCTATGA CATGCTGCCT 
TCCGTCCTCA GTGCAGATTT GTGTTCCCTT CTGGGAGGCG TTGATAGGTA TGCTGTAAGC 
ATCATGTGGG AACTGGATAA AGCCTCTTAT GAAATTAAGA AAGTGTGGTA TGGCAGAACC 
ATTATTCGAT CAGCATACAA ACTGTTCTAT GAAGCAGCCC AAGAACTACT GGATGGAAAC 
TTAAGCGTTG TTGATGATAT TCCAGAATTC AAAGACTTGG ATGAGAAGAG CAGACAAGCC 
AAGCTGGAGG AGTTGGTGTG GGCAATTGGA AAGCTGACCG ACATAGCTCG CCATGTCAGA 
GCTAAACGAG ACGGATGTGG TGCCCTGGAA CTGGAAGGGG TAGAGGTTTG CGTACAGCTA 
GATGACAAAA AGAACATTCA CGACCTCATC CCCAAGCAGC CCCTGGAAGT CCACGAGACA 
GTGGCTGAAT GCATGATCCT GGCCAACCAC TGGGTCGCCA AAAAGATCTG GGAGAGCTTC 
CCTCATCAGG CCTTGCTGCG CCAGCACCCT CCTCCACACC AGGAGTTCTT TTCAGAACTC 
CGGGAATGTG CTAAAGCCAA AGGCTTCTTC ATAGATACAC GGTCCAATAA AACACTGGCT 
GATTCTCTGG ATAATGCGAA CGACCCCCAC GATCCCATTG TGAACAGGCT ACTGCGCTCC 
ATGGCCACGC AGGCCATGTC GAATGCTCTG TACTTCTCCA CCGGATCCTG TGCGGAGGAG 
GAGTTCCATC ATTACGGTCT TGCATTAGAT AAATATACCC ACTTTACTTC TCCAATAAGA 
AGATATTCAG ATATTGTAGT ACACCGCTTG TTAATGGCAG CCATTTCAAA AGATAAGAAA 
ATGGAAATTA AGGGAAATCT GTTCAGCAAC AAAGATCTTG AGGAATTATG CAGACATATC 
AACAACAGAA ACCAAGCAGC ACAGCATTCT CAGAAGCAGT CTACTGAGCT CTTCCAGTGC 
ATGTACTTCA AAGACAAAGA CCCTGCCACC GAGGAGCGTT GCATATCTGA CGGAGTTATT 
TATTCAATTA GAACAAATGG TGTGCTTCTA TTTATACCAA GGTTTGGGAT TAAAGGTGCT 
GCTTATCTAA AAAATAAAGA TGGTTTAGTC ATCTCATGTG GCCCAGATAG CTGTTCTGAA 
TGGAAACCAG GATCCCTTCA ACGATTTCAA AACAAAATTA CCTCTACTAC AACAGATGGG 
GAATCTGTTA CGTTCCATTT GTTTGACCAT GTAACCGTAA GAATATCCAT ACAGGCCTCA 
CGTTGCCATT CTGATACAAT CAGACTTGAA ATAATTAGTA ACAAACCATA CAAGATACCA 
AATACAGAAC TTATTCATCA GAGTTCCCCC TTGCTGAAGA GTGAGTTAGT GAAAGAAGTA 
ACTAAATCTG TGGAAGAAGC TCAGCTTGCC CAAGAAGTCA AAGTAAACAT CATTCAGGAG 
GAATATCAAG AATATCGCCA AACAAAGGGA AGGAGCCTAT ACACACTTCT AGAGGAGATA 
CGGGACCTAG CTCTCCTGGA TGTTTCAAAC AATTATGGAA TATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

DIS3L ( NM_001323945.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_001310874.1 Homo sapiens DIS3 like exosome 3'-5' exoribonuclease (DIS3L), transcript variant 11, mRNA.

Price & Availability↑

CloneID	OHu09544
Clone ID Related Accession (Same CDS sequence)	NM_001323945.2 , XM_005254147.3 , XM_005254145.2 , NM_001323936.2 , NM_133375.5 , NM_133375.4 , NM_001323945.1 , NM_001323936.1 , NM_133375.3
Accession Version	NM_001323945.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2916bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-09-27
Organism	Homo sapiens(human)
Product	DIS3-like exonuclease 1 isoform 2
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AC055855.9. On May 31, 2019 this sequence version replaced NM_001323945.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. ##Evidence-Data-START## Transcript exon combination :: SRR1803614.103133.1, SRR1803614.277865.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1966682, SAMEA1968189 [ECO:0000348] ##Evidence-Data-END##

ATGCAGACAG CTTGTCAAGC TGTGCAGCAT CAAAGAGGCA GGAGACAGTA TAACAAACTG 
CGAAACCTGC TGAAGGATGC GCGTCATGAT TGCATTCTCT TTGCTAATGA ATTCCAGCAA 
TGCTGCTATC TGCCACGGGA AAGAGGAGAG TCCATGGAGA AGTGGCAGAC CAGGAGCATA 
TACAACGCAG CTGTTTGGTA CTATCATCAC TGCCAGGACA GGATGCCAAT TGTTATGGTG 
ACAGAAGATG AAGAGGCAAT TCAGCAGTAT GGAAGTGAAA CAGAAGGAGT ATTCGTGATT 
ACTTTCAAGA ATTACCTGGA CAATTTCTGG CCTGATTTAA AAGCTGCCCA CGAGCTTTGT 
GATTCTATCC TTCAGTCTCG ACGGGAGAGA GAGAATGAGA GTCAGGAGAG CCATGGGAAG 
GAGTACCCAG AACATCTTCC CCTGGAAGTG TTAGAAGCTG GGATTAAATC TGGACGCTAT 
ATCCAGGGAA TTCTGAATGT CAACAAACAC AGAGCCCAAA TAGAAGCTTT TGTTCGACTT 
CAAGGAGCCA GCAGTAAAGA TTCAGATTTA GTCAGTGACA TCCTAATCCA CGGGATGAAG 
GCTCGAAACC GCTCAATTCA TGGAGATGTG GTAGTTGTGG AGCTGCTTCC TAAAAATGAA 
TGGAAAGGAA GAACCGTAGC CCTGTGTGAG AATGACTGTG ACGACAAGGC TTCGGGCGAG 
TCCCCAAGTG AGCCCATGCC TACAGGTCGA GTGGTGGGCA TACTTCAGAA GAACTGGCGG 
GATTATGTGG TGACATTTCC GTCCAAAGAA GAGGTCCAAT CTCAGGGCAA AAATGCTCAG 
AAAATCCTGG TTACACCTTG GGATTACAGA ATTCCCAAAA TTCGAATTAG CACTCAGCAA 
GCAGAAACCC TCCAGGACTT CAGGGTGGTC GTGCGCATCG ATTCCTGGGA GTCAACATCT 
GTGTATCCAA ATGGACATTT TGTGCGTGTT TTAGGAAGAA TCGGAGATCT GGAAGGGGAA 
ATTGCAACCA TCCTGGTGGA AAACAGTATT TCAGTTATTC CTTTCTCAGA AGCTCAGATG 
TGTGAGATGC CAGTAAACAC ACCAGAAAGT CCCTGGAAGG TGAGTCCTGA AGAGGAACAA 
AAACGTAAAG ACTTGAGGAA AAGCCATCTC GTATTCAGCA TTGACCCCAA AGGTTGTGAA 
GATGTGGATG ACACACTCTC AGTCAGAACC TTAAATAATG GCAACCTGGA ACTTGGGGTC 
CACATCGCAG ATGTAACACA CTTTGTGGCA CCAAATTCTT ACATTGATAT TGAAGCTAGA 
ACAAGGGCCA CCACTTATTA TCTAGCAGAT CGTCGCTATG ACATGCTGCC TTCCGTCCTC 
AGTGCAGATT TGTGTTCCCT TCTGGGAGGC GTTGATAGGT ATGCTGTAAG CATCATGTGG 
GAACTGGATA AAGCCTCTTA TGAAATTAAG AAAGTGTGGT ATGGCAGAAC CATTATTCGA 
TCAGCATACA AACTGTTCTA TGAAGCAGCC CAAGAACTAC TGGATGGAAA CTTAAGCGTT 
GTTGATGATA TTCCAGAATT CAAAGACTTG GATGAGAAGA GCAGACAAGC CAAGCTGGAG 
GAGTTGGTGT GGGCAATTGG AAAGCTGACC GACATAGCTC GCCATGTCAG AGCTAAACGA 
GACGGATGTG GTGCCCTGGA ACTGGAAGGG GTAGAGGTTT GCGTACAGCT AGATGACAAA 
AAGAACATTC ACGACCTCAT CCCCAAGCAG CCCCTGGAAG TCCACGAGAC AGTGGCTGAA 
TGCATGATCC TGGCCAACCA CTGGGTCGCC AAAAAGATCT GGGAGAGCTT CCCTCATCAG 
GCCTTGCTGC GCCAGCACCC TCCTCCACAC CAGGAGTTCT TTTCAGAACT CCGGGAATGT 
GCTAAAGCCA AAGGCTTCTT CATAGATACA CGGTCCAATA AAACACTGGC TGATTCTCTG 
GATAATGCGA ACGACCCCCA CGATCCCATT GTGAACAGGC TACTGCGCTC CATGGCCACG 
CAGGCCATGT CGAATGCTCT GTACTTCTCC ACCGGATCCT GTGCGGAGGA GGAGTTCCAT 
CATTACGGTC TTGCATTAGA TAAATATACC CACTTTACTT CTCCAATAAG AAGATATTCA 
GATATTGTAG TACACCGCTT GTTAATGGCA GCCATTTCAA AAGATAAGAA AATGGAAATT 
AAGGGAAATC TGTTCAGCAA CAAAGATCTT GAGGAATTAT GCAGACATAT CAACAACAGA 
AACCAAGCAG CACAGCATTC TCAGAAGCAG TCTACTGAGC TCTTCCAGTG CATGTACTTC 
AAAGACAAAG ACCCTGCCAC CGAGGAGCGT TGCATATCTG ACGGAGTTAT TTATTCAATT 
AGAACAAATG GTGTGCTTCT ATTTATACCA AGGTTTGGGA TTAAAGGTGC TGCTTATCTA 
AAAAATAAAG ATGGTTTAGT CATCTCATGT GGCCCAGATA GCTGTTCTGA ATGGAAACCA 
GGATCCCTTC AACGATTTCA AAACAAAATT ACCTCTACTA CAACAGATGG GGAATCTGTT 
ACGTTCCATT TGTTTGACCA TGTAACCGTA AGAATATCCA TACAGGCCTC ACGTTGCCAT 
TCTGATACAA TCAGACTTGA AATAATTAGT AACAAACCAT ACAAGATACC AAATACAGAA 
CTTATTCATC AGAGTTCCCC CTTGCTGAAG AGTGAGTTAG TGAAAGAAGT AACTAAATCT 
GTGGAAGAAG CTCAGCTTGC CCAAGAAGTC AAAGTAAACA TCATTCAGGA GGAATATCAA 
GAATATCGCC AAACAAAGGG AAGGAGCCTA TACACACTTC TAGAGGAGAT ACGGGACCTA 
GCTCTCCTGG ATGTTTCAAA CAATTATGGA ATATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001310874.1
CDS	745..3660
Translation	MQTACQAVQHQRGRRQYNKLRNLLKDARHDCILFANEFQQCCYLPRERGESMEKWQTRSIYNAAVWYYHHCQDRMPIVMVTEDEEAIQQYGSETEGVFVITFKNYLDNFWPDLKAAHELCDSILQSRRERENESQESHGKEYPEHLPLEVLEAGIKSGRYIQGILNVNKHRAQIEAFVRLQGASSKDSDLVSDILIHGMKARNRSIHGDVVVVELLPKNEWKGRTVALCENDCDDKASGESPSEPMPTGRVVGILQKNWRDYVVTFPSKEEVQSQGKNAQKILVTPWDYRIPKIRISTQQAETLQDFRVVVRIDSWESTSVYPNGHFVRVLGRIGDLEGEIATILVENSISVIPFSEAQMCEMPVNTPESPWKVSPEEEQKRKDLRKSHLVFSIDPKGCEDVDDTLSVRTLNNGNLELGVHIADVTHFVAPNSYIDIEARTRATTYYLADRRYDMLPSVLSADLCSLLGGVDRYAVSIMWELDKASYEIKKVWYGRTIIRSAYKLFYEAAQELLDGNLSVVDDIPEFKDLDEKSRQAKLEELVWAIGKLTDIARHVRAKRDGCGALELEGVEVCVQLDDKKNIHDLIPKQPLEVHETVAECMILANHWVAKKIWESFPHQALLRQHPPPHQEFFSELRECAKAKGFFIDTRSNKTLADSLDNANDPHDPIVNRLLRSMATQAMSNALYFSTGSCAEEEFHHYGLALDKYTHFTSPIRRYSDIVVHRLLMAAISKDKKMEIKGNLFSNKDLEELCRHINNRNQAAQHSQKQSTELFQCMYFKDKDPATEERCISDGVIYSIRTNGVLLFIPRFGIKGAAYLKNKDGLVISCGPDSCSEWKPGSLQRFQNKITSTTTDGESVTFHLFDHVTVRISIQASRCHSDTIRLEIISNKPYKIPNTELIHQSSPLLKSELVKEVTKSVEEAQLAQEVKVNIIQEEYQEYRQTKGRSLYTLLEEIRDLALLDVSNNYGI

Target ORF information:

RefSeq Version	NM_001323945.2
Organism	Homo sapiens(human)
Definition	Homo sapiens DIS3 like exosome 3'-5' exoribonuclease (DIS3L), transcript variant 11, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001323945.2

ORF Insert Sequence:

ATGCAGACAG CTTGTCAAGC TGTGCAGCAT CAAAGAGGCA GGAGACAGTA TAACAAACTG 
CGAAACCTGC TGAAGGATGC GCGTCATGAT TGCATTCTCT TTGCTAATGA ATTCCAGCAA 
TGCTGCTATC TGCCACGGGA AAGAGGAGAG TCCATGGAGA AGTGGCAGAC CAGGAGCATA 
TACAACGCAG CTGTTTGGTA CTATCATCAC TGCCAGGACA GGATGCCAAT TGTTATGGTG 
ACAGAAGATG AAGAGGCAAT TCAGCAGTAT GGAAGTGAAA CAGAAGGAGT ATTCGTGATT 
ACTTTCAAGA ATTACCTGGA CAATTTCTGG CCTGATTTAA AAGCTGCCCA CGAGCTTTGT 
GATTCTATCC TTCAGTCTCG ACGGGAGAGA GAGAATGAGA GTCAGGAGAG CCATGGGAAG 
GAGTACCCAG AACATCTTCC CCTGGAAGTG TTAGAAGCTG GGATTAAATC TGGACGCTAT 
ATCCAGGGAA TTCTGAATGT CAACAAACAC AGAGCCCAAA TAGAAGCTTT TGTTCGACTT 
CAAGGAGCCA GCAGTAAAGA TTCAGATTTA GTCAGTGACA TCCTAATCCA CGGGATGAAG 
GCTCGAAACC GCTCAATTCA TGGAGATGTG GTAGTTGTGG AGCTGCTTCC TAAAAATGAA 
TGGAAAGGAA GAACCGTAGC CCTGTGTGAG AATGACTGTG ACGACAAGGC TTCGGGCGAG 
TCCCCAAGTG AGCCCATGCC TACAGGTCGA GTGGTGGGCA TACTTCAGAA GAACTGGCGG 
GATTATGTGG TGACATTTCC GTCCAAAGAA GAGGTCCAAT CTCAGGGCAA AAATGCTCAG 
AAAATCCTGG TTACACCTTG GGATTACAGA ATTCCCAAAA TTCGAATTAG CACTCAGCAA 
GCAGAAACCC TCCAGGACTT CAGGGTGGTC GTGCGCATCG ATTCCTGGGA GTCAACATCT 
GTGTATCCAA ATGGACATTT TGTGCGTGTT TTAGGAAGAA TCGGAGATCT GGAAGGGGAA 
ATTGCAACCA TCCTGGTGGA AAACAGTATT TCAGTTATTC CTTTCTCAGA AGCTCAGATG 
TGTGAGATGC CAGTAAACAC ACCAGAAAGT CCCTGGAAGG TGAGTCCTGA AGAGGAACAA 
AAACGTAAAG ACTTGAGGAA AAGCCATCTC GTATTCAGCA TTGACCCCAA AGGTTGTGAA 
GATGTGGATG ACACACTCTC AGTCAGAACC TTAAATAATG GCAACCTGGA ACTTGGGGTC 
CACATCGCAG ATGTAACACA CTTTGTGGCA CCAAATTCTT ACATTGATAT TGAAGCTAGA 
ACAAGGGCCA CCACTTATTA TCTAGCAGAT CGTCGCTATG ACATGCTGCC TTCCGTCCTC 
AGTGCAGATT TGTGTTCCCT TCTGGGAGGC GTTGATAGGT ATGCTGTAAG CATCATGTGG 
GAACTGGATA AAGCCTCTTA TGAAATTAAG AAAGTGTGGT ATGGCAGAAC CATTATTCGA 
TCAGCATACA AACTGTTCTA TGAAGCAGCC CAAGAACTAC TGGATGGAAA CTTAAGCGTT 
GTTGATGATA TTCCAGAATT CAAAGACTTG GATGAGAAGA GCAGACAAGC CAAGCTGGAG 
GAGTTGGTGT GGGCAATTGG AAAGCTGACC GACATAGCTC GCCATGTCAG AGCTAAACGA 
GACGGATGTG GTGCCCTGGA ACTGGAAGGG GTAGAGGTTT GCGTACAGCT AGATGACAAA 
AAGAACATTC ACGACCTCAT CCCCAAGCAG CCCCTGGAAG TCCACGAGAC AGTGGCTGAA 
TGCATGATCC TGGCCAACCA CTGGGTCGCC AAAAAGATCT GGGAGAGCTT CCCTCATCAG 
GCCTTGCTGC GCCAGCACCC TCCTCCACAC CAGGAGTTCT TTTCAGAACT CCGGGAATGT 
GCTAAAGCCA AAGGCTTCTT CATAGATACA CGGTCCAATA AAACACTGGC TGATTCTCTG 
GATAATGCGA ACGACCCCCA CGATCCCATT GTGAACAGGC TACTGCGCTC CATGGCCACG 
CAGGCCATGT CGAATGCTCT GTACTTCTCC ACCGGATCCT GTGCGGAGGA GGAGTTCCAT 
CATTACGGTC TTGCATTAGA TAAATATACC CACTTTACTT CTCCAATAAG AAGATATTCA 
GATATTGTAG TACACCGCTT GTTAATGGCA GCCATTTCAA AAGATAAGAA AATGGAAATT 
AAGGGAAATC TGTTCAGCAA CAAAGATCTT GAGGAATTAT GCAGACATAT CAACAACAGA 
AACCAAGCAG CACAGCATTC TCAGAAGCAG TCTACTGAGC TCTTCCAGTG CATGTACTTC 
AAAGACAAAG ACCCTGCCAC CGAGGAGCGT TGCATATCTG ACGGAGTTAT TTATTCAATT 
AGAACAAATG GTGTGCTTCT ATTTATACCA AGGTTTGGGA TTAAAGGTGC TGCTTATCTA 
AAAAATAAAG ATGGTTTAGT CATCTCATGT GGCCCAGATA GCTGTTCTGA ATGGAAACCA 
GGATCCCTTC AACGATTTCA AAACAAAATT ACCTCTACTA CAACAGATGG GGAATCTGTT 
ACGTTCCATT TGTTTGACCA TGTAACCGTA AGAATATCCA TACAGGCCTC ACGTTGCCAT 
TCTGATACAA TCAGACTTGA AATAATTAGT AACAAACCAT ACAAGATACC AAATACAGAA 
CTTATTCATC AGAGTTCCCC CTTGCTGAAG AGTGAGTTAG TGAAAGAAGT AACTAAATCT 
GTGGAAGAAG CTCAGCTTGC CCAAGAAGTC AAAGTAAACA TCATTCAGGA GGAATATCAA 
GAATATCGCC AAACAAAGGG AAGGAGCCTA TACACACTTC TAGAGGAGAT ACGGGACCTA 
GCTCTCCTGG ATGTTTCAAA CAATTATGGA ATATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

DIS3L ( NM_001323936.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_001310865.1 Homo sapiens DIS3 like exosome 3'-5' exoribonuclease (DIS3L), transcript variant 3, mRNA.

Price & Availability↑

CloneID	OHu09544
Clone ID Related Accession (Same CDS sequence)	NM_001323945.2 , XM_005254147.3 , XM_005254145.2 , NM_001323936.2 , NM_133375.5 , NM_133375.4 , NM_001323945.1 , NM_001323936.1 , NM_133375.3
Accession Version	NM_001323936.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2916bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-09-27
Organism	Homo sapiens(human)
Product	DIS3-like exonuclease 1 isoform 2
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AC055855.9. On May 31, 2019 this sequence version replaced NM_001323936.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. ##Evidence-Data-START## Transcript exon combination :: SRR1660809.51129.1, SRR1660803.119786.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1968540 [ECO:0000348] ##Evidence-Data-END##

ATGCAGACAG CTTGTCAAGC TGTGCAGCAT CAAAGAGGCA GGAGACAGTA TAACAAACTG 
CGAAACCTGC TGAAGGATGC GCGTCATGAT TGCATTCTCT TTGCTAATGA ATTCCAGCAA 
TGCTGCTATC TGCCACGGGA AAGAGGAGAG TCCATGGAGA AGTGGCAGAC CAGGAGCATA 
TACAACGCAG CTGTTTGGTA CTATCATCAC TGCCAGGACA GGATGCCAAT TGTTATGGTG 
ACAGAAGATG AAGAGGCAAT TCAGCAGTAT GGAAGTGAAA CAGAAGGAGT ATTCGTGATT 
ACTTTCAAGA ATTACCTGGA CAATTTCTGG CCTGATTTAA AAGCTGCCCA CGAGCTTTGT 
GATTCTATCC TTCAGTCTCG ACGGGAGAGA GAGAATGAGA GTCAGGAGAG CCATGGGAAG 
GAGTACCCAG AACATCTTCC CCTGGAAGTG TTAGAAGCTG GGATTAAATC TGGACGCTAT 
ATCCAGGGAA TTCTGAATGT CAACAAACAC AGAGCCCAAA TAGAAGCTTT TGTTCGACTT 
CAAGGAGCCA GCAGTAAAGA TTCAGATTTA GTCAGTGACA TCCTAATCCA CGGGATGAAG 
GCTCGAAACC GCTCAATTCA TGGAGATGTG GTAGTTGTGG AGCTGCTTCC TAAAAATGAA 
TGGAAAGGAA GAACCGTAGC CCTGTGTGAG AATGACTGTG ACGACAAGGC TTCGGGCGAG 
TCCCCAAGTG AGCCCATGCC TACAGGTCGA GTGGTGGGCA TACTTCAGAA GAACTGGCGG 
GATTATGTGG TGACATTTCC GTCCAAAGAA GAGGTCCAAT CTCAGGGCAA AAATGCTCAG 
AAAATCCTGG TTACACCTTG GGATTACAGA ATTCCCAAAA TTCGAATTAG CACTCAGCAA 
GCAGAAACCC TCCAGGACTT CAGGGTGGTC GTGCGCATCG ATTCCTGGGA GTCAACATCT 
GTGTATCCAA ATGGACATTT TGTGCGTGTT TTAGGAAGAA TCGGAGATCT GGAAGGGGAA 
ATTGCAACCA TCCTGGTGGA AAACAGTATT TCAGTTATTC CTTTCTCAGA AGCTCAGATG 
TGTGAGATGC CAGTAAACAC ACCAGAAAGT CCCTGGAAGG TGAGTCCTGA AGAGGAACAA 
AAACGTAAAG ACTTGAGGAA AAGCCATCTC GTATTCAGCA TTGACCCCAA AGGTTGTGAA 
GATGTGGATG ACACACTCTC AGTCAGAACC TTAAATAATG GCAACCTGGA ACTTGGGGTC 
CACATCGCAG ATGTAACACA CTTTGTGGCA CCAAATTCTT ACATTGATAT TGAAGCTAGA 
ACAAGGGCCA CCACTTATTA TCTAGCAGAT CGTCGCTATG ACATGCTGCC TTCCGTCCTC 
AGTGCAGATT TGTGTTCCCT TCTGGGAGGC GTTGATAGGT ATGCTGTAAG CATCATGTGG 
GAACTGGATA AAGCCTCTTA TGAAATTAAG AAAGTGTGGT ATGGCAGAAC CATTATTCGA 
TCAGCATACA AACTGTTCTA TGAAGCAGCC CAAGAACTAC TGGATGGAAA CTTAAGCGTT 
GTTGATGATA TTCCAGAATT CAAAGACTTG GATGAGAAGA GCAGACAAGC CAAGCTGGAG 
GAGTTGGTGT GGGCAATTGG AAAGCTGACC GACATAGCTC GCCATGTCAG AGCTAAACGA 
GACGGATGTG GTGCCCTGGA ACTGGAAGGG GTAGAGGTTT GCGTACAGCT AGATGACAAA 
AAGAACATTC ACGACCTCAT CCCCAAGCAG CCCCTGGAAG TCCACGAGAC AGTGGCTGAA 
TGCATGATCC TGGCCAACCA CTGGGTCGCC AAAAAGATCT GGGAGAGCTT CCCTCATCAG 
GCCTTGCTGC GCCAGCACCC TCCTCCACAC CAGGAGTTCT TTTCAGAACT CCGGGAATGT 
GCTAAAGCCA AAGGCTTCTT CATAGATACA CGGTCCAATA AAACACTGGC TGATTCTCTG 
GATAATGCGA ACGACCCCCA CGATCCCATT GTGAACAGGC TACTGCGCTC CATGGCCACG 
CAGGCCATGT CGAATGCTCT GTACTTCTCC ACCGGATCCT GTGCGGAGGA GGAGTTCCAT 
CATTACGGTC TTGCATTAGA TAAATATACC CACTTTACTT CTCCAATAAG AAGATATTCA 
GATATTGTAG TACACCGCTT GTTAATGGCA GCCATTTCAA AAGATAAGAA AATGGAAATT 
AAGGGAAATC TGTTCAGCAA CAAAGATCTT GAGGAATTAT GCAGACATAT CAACAACAGA 
AACCAAGCAG CACAGCATTC TCAGAAGCAG TCTACTGAGC TCTTCCAGTG CATGTACTTC 
AAAGACAAAG ACCCTGCCAC CGAGGAGCGT TGCATATCTG ACGGAGTTAT TTATTCAATT 
AGAACAAATG GTGTGCTTCT ATTTATACCA AGGTTTGGGA TTAAAGGTGC TGCTTATCTA 
AAAAATAAAG ATGGTTTAGT CATCTCATGT GGCCCAGATA GCTGTTCTGA ATGGAAACCA 
GGATCCCTTC AACGATTTCA AAACAAAATT ACCTCTACTA CAACAGATGG GGAATCTGTT 
ACGTTCCATT TGTTTGACCA TGTAACCGTA AGAATATCCA TACAGGCCTC ACGTTGCCAT 
TCTGATACAA TCAGACTTGA AATAATTAGT AACAAACCAT ACAAGATACC AAATACAGAA 
CTTATTCATC AGAGTTCCCC CTTGCTGAAG AGTGAGTTAG TGAAAGAAGT AACTAAATCT 
GTGGAAGAAG CTCAGCTTGC CCAAGAAGTC AAAGTAAACA TCATTCAGGA GGAATATCAA 
GAATATCGCC AAACAAAGGG AAGGAGCCTA TACACACTTC TAGAGGAGAT ACGGGACCTA 
GCTCTCCTGG ATGTTTCAAA CAATTATGGA ATATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001310865.1
CDS	139..3054
Translation	MQTACQAVQHQRGRRQYNKLRNLLKDARHDCILFANEFQQCCYLPRERGESMEKWQTRSIYNAAVWYYHHCQDRMPIVMVTEDEEAIQQYGSETEGVFVITFKNYLDNFWPDLKAAHELCDSILQSRRERENESQESHGKEYPEHLPLEVLEAGIKSGRYIQGILNVNKHRAQIEAFVRLQGASSKDSDLVSDILIHGMKARNRSIHGDVVVVELLPKNEWKGRTVALCENDCDDKASGESPSEPMPTGRVVGILQKNWRDYVVTFPSKEEVQSQGKNAQKILVTPWDYRIPKIRISTQQAETLQDFRVVVRIDSWESTSVYPNGHFVRVLGRIGDLEGEIATILVENSISVIPFSEAQMCEMPVNTPESPWKVSPEEEQKRKDLRKSHLVFSIDPKGCEDVDDTLSVRTLNNGNLELGVHIADVTHFVAPNSYIDIEARTRATTYYLADRRYDMLPSVLSADLCSLLGGVDRYAVSIMWELDKASYEIKKVWYGRTIIRSAYKLFYEAAQELLDGNLSVVDDIPEFKDLDEKSRQAKLEELVWAIGKLTDIARHVRAKRDGCGALELEGVEVCVQLDDKKNIHDLIPKQPLEVHETVAECMILANHWVAKKIWESFPHQALLRQHPPPHQEFFSELRECAKAKGFFIDTRSNKTLADSLDNANDPHDPIVNRLLRSMATQAMSNALYFSTGSCAEEEFHHYGLALDKYTHFTSPIRRYSDIVVHRLLMAAISKDKKMEIKGNLFSNKDLEELCRHINNRNQAAQHSQKQSTELFQCMYFKDKDPATEERCISDGVIYSIRTNGVLLFIPRFGIKGAAYLKNKDGLVISCGPDSCSEWKPGSLQRFQNKITSTTTDGESVTFHLFDHVTVRISIQASRCHSDTIRLEIISNKPYKIPNTELIHQSSPLLKSELVKEVTKSVEEAQLAQEVKVNIIQEEYQEYRQTKGRSLYTLLEEIRDLALLDVSNNYGI

Target ORF information:

RefSeq Version	NM_001323936.2
Organism	Homo sapiens(human)
Definition	Homo sapiens DIS3 like exosome 3'-5' exoribonuclease (DIS3L), transcript variant 3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001323936.2

ORF Insert Sequence:

ATGCAGACAG CTTGTCAAGC TGTGCAGCAT CAAAGAGGCA GGAGACAGTA TAACAAACTG 
CGAAACCTGC TGAAGGATGC GCGTCATGAT TGCATTCTCT TTGCTAATGA ATTCCAGCAA 
TGCTGCTATC TGCCACGGGA AAGAGGAGAG TCCATGGAGA AGTGGCAGAC CAGGAGCATA 
TACAACGCAG CTGTTTGGTA CTATCATCAC TGCCAGGACA GGATGCCAAT TGTTATGGTG 
ACAGAAGATG AAGAGGCAAT TCAGCAGTAT GGAAGTGAAA CAGAAGGAGT ATTCGTGATT 
ACTTTCAAGA ATTACCTGGA CAATTTCTGG CCTGATTTAA AAGCTGCCCA CGAGCTTTGT 
GATTCTATCC TTCAGTCTCG ACGGGAGAGA GAGAATGAGA GTCAGGAGAG CCATGGGAAG 
GAGTACCCAG AACATCTTCC CCTGGAAGTG TTAGAAGCTG GGATTAAATC TGGACGCTAT 
ATCCAGGGAA TTCTGAATGT CAACAAACAC AGAGCCCAAA TAGAAGCTTT TGTTCGACTT 
CAAGGAGCCA GCAGTAAAGA TTCAGATTTA GTCAGTGACA TCCTAATCCA CGGGATGAAG 
GCTCGAAACC GCTCAATTCA TGGAGATGTG GTAGTTGTGG AGCTGCTTCC TAAAAATGAA 
TGGAAAGGAA GAACCGTAGC CCTGTGTGAG AATGACTGTG ACGACAAGGC TTCGGGCGAG 
TCCCCAAGTG AGCCCATGCC TACAGGTCGA GTGGTGGGCA TACTTCAGAA GAACTGGCGG 
GATTATGTGG TGACATTTCC GTCCAAAGAA GAGGTCCAAT CTCAGGGCAA AAATGCTCAG 
AAAATCCTGG TTACACCTTG GGATTACAGA ATTCCCAAAA TTCGAATTAG CACTCAGCAA 
GCAGAAACCC TCCAGGACTT CAGGGTGGTC GTGCGCATCG ATTCCTGGGA GTCAACATCT 
GTGTATCCAA ATGGACATTT TGTGCGTGTT TTAGGAAGAA TCGGAGATCT GGAAGGGGAA 
ATTGCAACCA TCCTGGTGGA AAACAGTATT TCAGTTATTC CTTTCTCAGA AGCTCAGATG 
TGTGAGATGC CAGTAAACAC ACCAGAAAGT CCCTGGAAGG TGAGTCCTGA AGAGGAACAA 
AAACGTAAAG ACTTGAGGAA AAGCCATCTC GTATTCAGCA TTGACCCCAA AGGTTGTGAA 
GATGTGGATG ACACACTCTC AGTCAGAACC TTAAATAATG GCAACCTGGA ACTTGGGGTC 
CACATCGCAG ATGTAACACA CTTTGTGGCA CCAAATTCTT ACATTGATAT TGAAGCTAGA 
ACAAGGGCCA CCACTTATTA TCTAGCAGAT CGTCGCTATG ACATGCTGCC TTCCGTCCTC 
AGTGCAGATT TGTGTTCCCT TCTGGGAGGC GTTGATAGGT ATGCTGTAAG CATCATGTGG 
GAACTGGATA AAGCCTCTTA TGAAATTAAG AAAGTGTGGT ATGGCAGAAC CATTATTCGA 
TCAGCATACA AACTGTTCTA TGAAGCAGCC CAAGAACTAC TGGATGGAAA CTTAAGCGTT 
GTTGATGATA TTCCAGAATT CAAAGACTTG GATGAGAAGA GCAGACAAGC CAAGCTGGAG 
GAGTTGGTGT GGGCAATTGG AAAGCTGACC GACATAGCTC GCCATGTCAG AGCTAAACGA 
GACGGATGTG GTGCCCTGGA ACTGGAAGGG GTAGAGGTTT GCGTACAGCT AGATGACAAA 
AAGAACATTC ACGACCTCAT CCCCAAGCAG CCCCTGGAAG TCCACGAGAC AGTGGCTGAA 
TGCATGATCC TGGCCAACCA CTGGGTCGCC AAAAAGATCT GGGAGAGCTT CCCTCATCAG 
GCCTTGCTGC GCCAGCACCC TCCTCCACAC CAGGAGTTCT TTTCAGAACT CCGGGAATGT 
GCTAAAGCCA AAGGCTTCTT CATAGATACA CGGTCCAATA AAACACTGGC TGATTCTCTG 
GATAATGCGA ACGACCCCCA CGATCCCATT GTGAACAGGC TACTGCGCTC CATGGCCACG 
CAGGCCATGT CGAATGCTCT GTACTTCTCC ACCGGATCCT GTGCGGAGGA GGAGTTCCAT 
CATTACGGTC TTGCATTAGA TAAATATACC CACTTTACTT CTCCAATAAG AAGATATTCA 
GATATTGTAG TACACCGCTT GTTAATGGCA GCCATTTCAA AAGATAAGAA AATGGAAATT 
AAGGGAAATC TGTTCAGCAA CAAAGATCTT GAGGAATTAT GCAGACATAT CAACAACAGA 
AACCAAGCAG CACAGCATTC TCAGAAGCAG TCTACTGAGC TCTTCCAGTG CATGTACTTC 
AAAGACAAAG ACCCTGCCAC CGAGGAGCGT TGCATATCTG ACGGAGTTAT TTATTCAATT 
AGAACAAATG GTGTGCTTCT ATTTATACCA AGGTTTGGGA TTAAAGGTGC TGCTTATCTA 
AAAAATAAAG ATGGTTTAGT CATCTCATGT GGCCCAGATA GCTGTTCTGA ATGGAAACCA 
GGATCCCTTC AACGATTTCA AAACAAAATT ACCTCTACTA CAACAGATGG GGAATCTGTT 
ACGTTCCATT TGTTTGACCA TGTAACCGTA AGAATATCCA TACAGGCCTC ACGTTGCCAT 
TCTGATACAA TCAGACTTGA AATAATTAGT AACAAACCAT ACAAGATACC AAATACAGAA 
CTTATTCATC AGAGTTCCCC CTTGCTGAAG AGTGAGTTAG TGAAAGAAGT AACTAAATCT 
GTGGAAGAAG CTCAGCTTGC CCAAGAAGTC AAAGTAAACA TCATTCAGGA GGAATATCAA 
GAATATCGCC AAACAAAGGG AAGGAGCCTA TACACACTTC TAGAGGAGAT ACGGGACCTA 
GCTCTCCTGG ATGTTTCAAA CAATTATGGA ATATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

DIS3L ( NM_133375.5 ) cDNA ORF clone, Homo sapiens(human) -> NP_588616.1 Homo sapiens DIS3 like exosome 3'-5' exoribonuclease (DIS3L), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu09544
Clone ID Related Accession (Same CDS sequence)	NM_001323945.2 , XM_005254147.3 , XM_005254145.2 , NM_001323936.2 , NM_133375.5 , NM_133375.4 , NM_001323945.1 , NM_001323936.1 , NM_133375.3
Accession Version	NM_133375.5 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2916bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-09-27
Organism	Homo sapiens(human)
Product	DIS3-like exonuclease 1 isoform 2
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AC055855.9. This sequence is a reference standard in the RefSeqGene project. On May 31, 2019 this sequence version replaced NM_133375.4. Transcript Variant: This variant (2) represents an alternate first exon and the transcript has a smaller open reading frame compared to variant 1. The resulting protein isoform (2) has a shorter N-terminus than isoform 1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. ##Evidence-Data-START## Transcript exon combination :: BC022089.2, SRR1803616.59524.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END##

ATGCAGACAG CTTGTCAAGC TGTGCAGCAT CAAAGAGGCA GGAGACAGTA TAACAAACTG 
CGAAACCTGC TGAAGGATGC GCGTCATGAT TGCATTCTCT TTGCTAATGA ATTCCAGCAA 
TGCTGCTATC TGCCACGGGA AAGAGGAGAG TCCATGGAGA AGTGGCAGAC CAGGAGCATA 
TACAACGCAG CTGTTTGGTA CTATCATCAC TGCCAGGACA GGATGCCAAT TGTTATGGTG 
ACAGAAGATG AAGAGGCAAT TCAGCAGTAT GGAAGTGAAA CAGAAGGAGT ATTCGTGATT 
ACTTTCAAGA ATTACCTGGA CAATTTCTGG CCTGATTTAA AAGCTGCCCA CGAGCTTTGT 
GATTCTATCC TTCAGTCTCG ACGGGAGAGA GAGAATGAGA GTCAGGAGAG CCATGGGAAG 
GAGTACCCAG AACATCTTCC CCTGGAAGTG TTAGAAGCTG GGATTAAATC TGGACGCTAT 
ATCCAGGGAA TTCTGAATGT CAACAAACAC AGAGCCCAAA TAGAAGCTTT TGTTCGACTT 
CAAGGAGCCA GCAGTAAAGA TTCAGATTTA GTCAGTGACA TCCTAATCCA CGGGATGAAG 
GCTCGAAACC GCTCAATTCA TGGAGATGTG GTAGTTGTGG AGCTGCTTCC TAAAAATGAA 
TGGAAAGGAA GAACCGTAGC CCTGTGTGAG AATGACTGTG ACGACAAGGC TTCGGGCGAG 
TCCCCAAGTG AGCCCATGCC TACAGGTCGA GTGGTGGGCA TACTTCAGAA GAACTGGCGG 
GATTATGTGG TGACATTTCC GTCCAAAGAA GAGGTCCAAT CTCAGGGCAA AAATGCTCAG 
AAAATCCTGG TTACACCTTG GGATTACAGA ATTCCCAAAA TTCGAATTAG CACTCAGCAA 
GCAGAAACCC TCCAGGACTT CAGGGTGGTC GTGCGCATCG ATTCCTGGGA GTCAACATCT 
GTGTATCCAA ATGGACATTT TGTGCGTGTT TTAGGAAGAA TCGGAGATCT GGAAGGGGAA 
ATTGCAACCA TCCTGGTGGA AAACAGTATT TCAGTTATTC CTTTCTCAGA AGCTCAGATG 
TGTGAGATGC CAGTAAACAC ACCAGAAAGT CCCTGGAAGG TGAGTCCTGA AGAGGAACAA 
AAACGTAAAG ACTTGAGGAA AAGCCATCTC GTATTCAGCA TTGACCCCAA AGGTTGTGAA 
GATGTGGATG ACACACTCTC AGTCAGAACC TTAAATAATG GCAACCTGGA ACTTGGGGTC 
CACATCGCAG ATGTAACACA CTTTGTGGCA CCAAATTCTT ACATTGATAT TGAAGCTAGA 
ACAAGGGCCA CCACTTATTA TCTAGCAGAT CGTCGCTATG ACATGCTGCC TTCCGTCCTC 
AGTGCAGATT TGTGTTCCCT TCTGGGAGGC GTTGATAGGT ATGCTGTAAG CATCATGTGG 
GAACTGGATA AAGCCTCTTA TGAAATTAAG AAAGTGTGGT ATGGCAGAAC CATTATTCGA 
TCAGCATACA AACTGTTCTA TGAAGCAGCC CAAGAACTAC TGGATGGAAA CTTAAGCGTT 
GTTGATGATA TTCCAGAATT CAAAGACTTG GATGAGAAGA GCAGACAAGC CAAGCTGGAG 
GAGTTGGTGT GGGCAATTGG AAAGCTGACC GACATAGCTC GCCATGTCAG AGCTAAACGA 
GACGGATGTG GTGCCCTGGA ACTGGAAGGG GTAGAGGTTT GCGTACAGCT AGATGACAAA 
AAGAACATTC ACGACCTCAT CCCCAAGCAG CCCCTGGAAG TCCACGAGAC AGTGGCTGAA 
TGCATGATCC TGGCCAACCA CTGGGTCGCC AAAAAGATCT GGGAGAGCTT CCCTCATCAG 
GCCTTGCTGC GCCAGCACCC TCCTCCACAC CAGGAGTTCT TTTCAGAACT CCGGGAATGT 
GCTAAAGCCA AAGGCTTCTT CATAGATACA CGGTCCAATA AAACACTGGC TGATTCTCTG 
GATAATGCGA ACGACCCCCA CGATCCCATT GTGAACAGGC TACTGCGCTC CATGGCCACG 
CAGGCCATGT CGAATGCTCT GTACTTCTCC ACCGGATCCT GTGCGGAGGA GGAGTTCCAT 
CATTACGGTC TTGCATTAGA TAAATATACC CACTTTACTT CTCCAATAAG AAGATATTCA 
GATATTGTAG TACACCGCTT GTTAATGGCA GCCATTTCAA AAGATAAGAA AATGGAAATT 
AAGGGAAATC TGTTCAGCAA CAAAGATCTT GAGGAATTAT GCAGACATAT CAACAACAGA 
AACCAAGCAG CACAGCATTC TCAGAAGCAG TCTACTGAGC TCTTCCAGTG CATGTACTTC 
AAAGACAAAG ACCCTGCCAC CGAGGAGCGT TGCATATCTG ACGGAGTTAT TTATTCAATT 
AGAACAAATG GTGTGCTTCT ATTTATACCA AGGTTTGGGA TTAAAGGTGC TGCTTATCTA 
AAAAATAAAG ATGGTTTAGT CATCTCATGT GGCCCAGATA GCTGTTCTGA ATGGAAACCA 
GGATCCCTTC AACGATTTCA AAACAAAATT ACCTCTACTA CAACAGATGG GGAATCTGTT 
ACGTTCCATT TGTTTGACCA TGTAACCGTA AGAATATCCA TACAGGCCTC ACGTTGCCAT 
TCTGATACAA TCAGACTTGA AATAATTAGT AACAAACCAT ACAAGATACC AAATACAGAA 
CTTATTCATC AGAGTTCCCC CTTGCTGAAG AGTGAGTTAG TGAAAGAAGT AACTAAATCT 
GTGGAAGAAG CTCAGCTTGC CCAAGAAGTC AAAGTAAACA TCATTCAGGA GGAATATCAA 
GAATATCGCC AAACAAAGGG AAGGAGCCTA TACACACTTC TAGAGGAGAT ACGGGACCTA 
GCTCTCCTGG ATGTTTCAAA CAATTATGGA ATATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_588616.1
CDS	170..3085
Translation	MQTACQAVQHQRGRRQYNKLRNLLKDARHDCILFANEFQQCCYLPRERGESMEKWQTRSIYNAAVWYYHHCQDRMPIVMVTEDEEAIQQYGSETEGVFVITFKNYLDNFWPDLKAAHELCDSILQSRRERENESQESHGKEYPEHLPLEVLEAGIKSGRYIQGILNVNKHRAQIEAFVRLQGASSKDSDLVSDILIHGMKARNRSIHGDVVVVELLPKNEWKGRTVALCENDCDDKASGESPSEPMPTGRVVGILQKNWRDYVVTFPSKEEVQSQGKNAQKILVTPWDYRIPKIRISTQQAETLQDFRVVVRIDSWESTSVYPNGHFVRVLGRIGDLEGEIATILVENSISVIPFSEAQMCEMPVNTPESPWKVSPEEEQKRKDLRKSHLVFSIDPKGCEDVDDTLSVRTLNNGNLELGVHIADVTHFVAPNSYIDIEARTRATTYYLADRRYDMLPSVLSADLCSLLGGVDRYAVSIMWELDKASYEIKKVWYGRTIIRSAYKLFYEAAQELLDGNLSVVDDIPEFKDLDEKSRQAKLEELVWAIGKLTDIARHVRAKRDGCGALELEGVEVCVQLDDKKNIHDLIPKQPLEVHETVAECMILANHWVAKKIWESFPHQALLRQHPPPHQEFFSELRECAKAKGFFIDTRSNKTLADSLDNANDPHDPIVNRLLRSMATQAMSNALYFSTGSCAEEEFHHYGLALDKYTHFTSPIRRYSDIVVHRLLMAAISKDKKMEIKGNLFSNKDLEELCRHINNRNQAAQHSQKQSTELFQCMYFKDKDPATEERCISDGVIYSIRTNGVLLFIPRFGIKGAAYLKNKDGLVISCGPDSCSEWKPGSLQRFQNKITSTTTDGESVTFHLFDHVTVRISIQASRCHSDTIRLEIISNKPYKIPNTELIHQSSPLLKSELVKEVTKSVEEAQLAQEVKVNIIQEEYQEYRQTKGRSLYTLLEEIRDLALLDVSNNYGI

Target ORF information:

RefSeq Version	NM_133375.5
Organism	Homo sapiens(human)
Definition	Homo sapiens DIS3 like exosome 3'-5' exoribonuclease (DIS3L), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_133375.5

ORF Insert Sequence:

ATGCAGACAG CTTGTCAAGC TGTGCAGCAT CAAAGAGGCA GGAGACAGTA TAACAAACTG 
CGAAACCTGC TGAAGGATGC GCGTCATGAT TGCATTCTCT TTGCTAATGA ATTCCAGCAA 
TGCTGCTATC TGCCACGGGA AAGAGGAGAG TCCATGGAGA AGTGGCAGAC CAGGAGCATA 
TACAACGCAG CTGTTTGGTA CTATCATCAC TGCCAGGACA GGATGCCAAT TGTTATGGTG 
ACAGAAGATG AAGAGGCAAT TCAGCAGTAT GGAAGTGAAA CAGAAGGAGT ATTCGTGATT 
ACTTTCAAGA ATTACCTGGA CAATTTCTGG CCTGATTTAA AAGCTGCCCA CGAGCTTTGT 
GATTCTATCC TTCAGTCTCG ACGGGAGAGA GAGAATGAGA GTCAGGAGAG CCATGGGAAG 
GAGTACCCAG AACATCTTCC CCTGGAAGTG TTAGAAGCTG GGATTAAATC TGGACGCTAT 
ATCCAGGGAA TTCTGAATGT CAACAAACAC AGAGCCCAAA TAGAAGCTTT TGTTCGACTT 
CAAGGAGCCA GCAGTAAAGA TTCAGATTTA GTCAGTGACA TCCTAATCCA CGGGATGAAG 
GCTCGAAACC GCTCAATTCA TGGAGATGTG GTAGTTGTGG AGCTGCTTCC TAAAAATGAA 
TGGAAAGGAA GAACCGTAGC CCTGTGTGAG AATGACTGTG ACGACAAGGC TTCGGGCGAG 
TCCCCAAGTG AGCCCATGCC TACAGGTCGA GTGGTGGGCA TACTTCAGAA GAACTGGCGG 
GATTATGTGG TGACATTTCC GTCCAAAGAA GAGGTCCAAT CTCAGGGCAA AAATGCTCAG 
AAAATCCTGG TTACACCTTG GGATTACAGA ATTCCCAAAA TTCGAATTAG CACTCAGCAA 
GCAGAAACCC TCCAGGACTT CAGGGTGGTC GTGCGCATCG ATTCCTGGGA GTCAACATCT 
GTGTATCCAA ATGGACATTT TGTGCGTGTT TTAGGAAGAA TCGGAGATCT GGAAGGGGAA 
ATTGCAACCA TCCTGGTGGA AAACAGTATT TCAGTTATTC CTTTCTCAGA AGCTCAGATG 
TGTGAGATGC CAGTAAACAC ACCAGAAAGT CCCTGGAAGG TGAGTCCTGA AGAGGAACAA 
AAACGTAAAG ACTTGAGGAA AAGCCATCTC GTATTCAGCA TTGACCCCAA AGGTTGTGAA 
GATGTGGATG ACACACTCTC AGTCAGAACC TTAAATAATG GCAACCTGGA ACTTGGGGTC 
CACATCGCAG ATGTAACACA CTTTGTGGCA CCAAATTCTT ACATTGATAT TGAAGCTAGA 
ACAAGGGCCA CCACTTATTA TCTAGCAGAT CGTCGCTATG ACATGCTGCC TTCCGTCCTC 
AGTGCAGATT TGTGTTCCCT TCTGGGAGGC GTTGATAGGT ATGCTGTAAG CATCATGTGG 
GAACTGGATA AAGCCTCTTA TGAAATTAAG AAAGTGTGGT ATGGCAGAAC CATTATTCGA 
TCAGCATACA AACTGTTCTA TGAAGCAGCC CAAGAACTAC TGGATGGAAA CTTAAGCGTT 
GTTGATGATA TTCCAGAATT CAAAGACTTG GATGAGAAGA GCAGACAAGC CAAGCTGGAG 
GAGTTGGTGT GGGCAATTGG AAAGCTGACC GACATAGCTC GCCATGTCAG AGCTAAACGA 
GACGGATGTG GTGCCCTGGA ACTGGAAGGG GTAGAGGTTT GCGTACAGCT AGATGACAAA 
AAGAACATTC ACGACCTCAT CCCCAAGCAG CCCCTGGAAG TCCACGAGAC AGTGGCTGAA 
TGCATGATCC TGGCCAACCA CTGGGTCGCC AAAAAGATCT GGGAGAGCTT CCCTCATCAG 
GCCTTGCTGC GCCAGCACCC TCCTCCACAC CAGGAGTTCT TTTCAGAACT CCGGGAATGT 
GCTAAAGCCA AAGGCTTCTT CATAGATACA CGGTCCAATA AAACACTGGC TGATTCTCTG 
GATAATGCGA ACGACCCCCA CGATCCCATT GTGAACAGGC TACTGCGCTC CATGGCCACG 
CAGGCCATGT CGAATGCTCT GTACTTCTCC ACCGGATCCT GTGCGGAGGA GGAGTTCCAT 
CATTACGGTC TTGCATTAGA TAAATATACC CACTTTACTT CTCCAATAAG AAGATATTCA 
GATATTGTAG TACACCGCTT GTTAATGGCA GCCATTTCAA AAGATAAGAA AATGGAAATT 
AAGGGAAATC TGTTCAGCAA CAAAGATCTT GAGGAATTAT GCAGACATAT CAACAACAGA 
AACCAAGCAG CACAGCATTC TCAGAAGCAG TCTACTGAGC TCTTCCAGTG CATGTACTTC 
AAAGACAAAG ACCCTGCCAC CGAGGAGCGT TGCATATCTG ACGGAGTTAT TTATTCAATT 
AGAACAAATG GTGTGCTTCT ATTTATACCA AGGTTTGGGA TTAAAGGTGC TGCTTATCTA 
AAAAATAAAG ATGGTTTAGT CATCTCATGT GGCCCAGATA GCTGTTCTGA ATGGAAACCA 
GGATCCCTTC AACGATTTCA AAACAAAATT ACCTCTACTA CAACAGATGG GGAATCTGTT 
ACGTTCCATT TGTTTGACCA TGTAACCGTA AGAATATCCA TACAGGCCTC ACGTTGCCAT 
TCTGATACAA TCAGACTTGA AATAATTAGT AACAAACCAT ACAAGATACC AAATACAGAA 
CTTATTCATC AGAGTTCCCC CTTGCTGAAG AGTGAGTTAG TGAAAGAAGT AACTAAATCT 
GTGGAAGAAG CTCAGCTTGC CCAAGAAGTC AAAGTAAACA TCATTCAGGA GGAATATCAA 
GAATATCGCC AAACAAAGGG AAGGAGCCTA TACACACTTC TAGAGGAGAT ACGGGACCTA 
GCTCTCCTGG ATGTTTCAAA CAATTATGGA ATATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

DIS3L ( NM_133375.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_588616.1 Homo sapiens DIS3 like exosome 3'-5' exoribonuclease (DIS3L), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu09544
Clone ID Related Accession (Same CDS sequence)	NM_001323945.2 , XM_005254147.3 , XM_005254145.2 , NM_001323936.2 , NM_133375.5 , NM_133375.4 , NM_001323945.1 , NM_001323936.1 , NM_133375.3
Accession Version	NM_133375.4	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2916bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2018-08-04
Organism	Homo sapiens(human)
Product	DIS3-like exonuclease 1 isoform 2
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AC055855.9. This sequence is a reference standard in the RefSeqGene project. On Apr 23, 2016 this sequence version replaced NM_133375.3. Transcript Variant: This variant (2) represents an alternate first exon and the transcript has a smaller open reading frame compared to variant 1. The resulting protein isoform (2) has a shorter N-terminus than isoform 1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. ##Evidence-Data-START## Transcript exon combination :: BC022089.2, SRR1803615.273867.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END##

ATGCAGACAG CTTGTCAAGC TGTGCAGCAT CAAAGAGGCA GGAGACAGTA TAACAAACTG 
CGAAACCTGC TGAAGGATGC GCGTCATGAT TGCATTCTCT TTGCTAATGA ATTCCAGCAA 
TGCTGCTATC TGCCACGGGA AAGAGGAGAG TCCATGGAGA AGTGGCAGAC CAGGAGCATA 
TACAACGCAG CTGTTTGGTA CTATCATCAC TGCCAGGACA GGATGCCAAT TGTTATGGTG 
ACAGAAGATG AAGAGGCAAT TCAGCAGTAT GGAAGTGAAA CAGAAGGAGT ATTCGTGATT 
ACTTTCAAGA ATTACCTGGA CAATTTCTGG CCTGATTTAA AAGCTGCCCA CGAGCTTTGT 
GATTCTATCC TTCAGTCTCG ACGGGAGAGA GAGAATGAGA GTCAGGAGAG CCATGGGAAG 
GAGTACCCAG AACATCTTCC CCTGGAAGTG TTAGAAGCTG GGATTAAATC TGGACGCTAT 
ATCCAGGGAA TTCTGAATGT CAACAAACAC AGAGCCCAAA TAGAAGCTTT TGTTCGACTT 
CAAGGAGCCA GCAGTAAAGA TTCAGATTTA GTCAGTGACA TCCTAATCCA CGGGATGAAG 
GCTCGAAACC GCTCAATTCA TGGAGATGTG GTAGTTGTGG AGCTGCTTCC TAAAAATGAA 
TGGAAAGGAA GAACCGTAGC CCTGTGTGAG AATGACTGTG ACGACAAGGC TTCGGGCGAG 
TCCCCAAGTG AGCCCATGCC TACAGGTCGA GTGGTGGGCA TACTTCAGAA GAACTGGCGG 
GATTATGTGG TGACATTTCC GTCCAAAGAA GAGGTCCAAT CTCAGGGCAA AAATGCTCAG 
AAAATCCTGG TTACACCTTG GGATTACAGA ATTCCCAAAA TTCGAATTAG CACTCAGCAA 
GCAGAAACCC TCCAGGACTT CAGGGTGGTC GTGCGCATCG ATTCCTGGGA GTCAACATCT 
GTGTATCCAA ATGGACATTT TGTGCGTGTT TTAGGAAGAA TCGGAGATCT GGAAGGGGAA 
ATTGCAACCA TCCTGGTGGA AAACAGTATT TCAGTTATTC CTTTCTCAGA AGCTCAGATG 
TGTGAGATGC CAGTAAACAC ACCAGAAAGT CCCTGGAAGG TGAGTCCTGA AGAGGAACAA 
AAACGTAAAG ACTTGAGGAA AAGCCATCTC GTATTCAGCA TTGACCCCAA AGGTTGTGAA 
GATGTGGATG ACACACTCTC AGTCAGAACC TTAAATAATG GCAACCTGGA ACTTGGGGTC 
CACATCGCAG ATGTAACACA CTTTGTGGCA CCAAATTCTT ACATTGATAT TGAAGCTAGA 
ACAAGGGCCA CCACTTATTA TCTAGCAGAT CGTCGCTATG ACATGCTGCC TTCCGTCCTC 
AGTGCAGATT TGTGTTCCCT TCTGGGAGGC GTTGATAGGT ATGCTGTAAG CATCATGTGG 
GAACTGGATA AAGCCTCTTA TGAAATTAAG AAAGTGTGGT ATGGCAGAAC CATTATTCGA 
TCAGCATACA AACTGTTCTA TGAAGCAGCC CAAGAACTAC TGGATGGAAA CTTAAGCGTT 
GTTGATGATA TTCCAGAATT CAAAGACTTG GATGAGAAGA GCAGACAAGC CAAGCTGGAG 
GAGTTGGTGT GGGCAATTGG AAAGCTGACC GACATAGCTC GCCATGTCAG AGCTAAACGA 
GACGGATGTG GTGCCCTGGA ACTGGAAGGG GTAGAGGTTT GCGTACAGCT AGATGACAAA 
AAGAACATTC ACGACCTCAT CCCCAAGCAG CCCCTGGAAG TCCACGAGAC AGTGGCTGAA 
TGCATGATCC TGGCCAACCA CTGGGTCGCC AAAAAGATCT GGGAGAGCTT CCCTCATCAG 
GCCTTGCTGC GCCAGCACCC TCCTCCACAC CAGGAGTTCT TTTCAGAACT CCGGGAATGT 
GCTAAAGCCA AAGGCTTCTT CATAGATACA CGGTCCAATA AAACACTGGC TGATTCTCTG 
GATAATGCGA ACGACCCCCA CGATCCCATT GTGAACAGGC TACTGCGCTC CATGGCCACG 
CAGGCCATGT CGAATGCTCT GTACTTCTCC ACCGGATCCT GTGCGGAGGA GGAGTTCCAT 
CATTACGGTC TTGCATTAGA TAAATATACC CACTTTACTT CTCCAATAAG AAGATATTCA 
GATATTGTAG TACACCGCTT GTTAATGGCA GCCATTTCAA AAGATAAGAA AATGGAAATT 
AAGGGAAATC TGTTCAGCAA CAAAGATCTT GAGGAATTAT GCAGACATAT CAACAACAGA 
AACCAAGCAG CACAGCATTC TCAGAAGCAG TCTACTGAGC TCTTCCAGTG CATGTACTTC 
AAAGACAAAG ACCCTGCCAC CGAGGAGCGT TGCATATCTG ACGGAGTTAT TTATTCAATT 
AGAACAAATG GTGTGCTTCT ATTTATACCA AGGTTTGGGA TTAAAGGTGC TGCTTATCTA 
AAAAATAAAG ATGGTTTAGT CATCTCATGT GGCCCAGATA GCTGTTCTGA ATGGAAACCA 
GGATCCCTTC AACGATTTCA AAACAAAATT ACCTCTACTA CAACAGATGG GGAATCTGTT 
ACGTTCCATT TGTTTGACCA TGTAACCGTA AGAATATCCA TACAGGCCTC ACGTTGCCAT 
TCTGATACAA TCAGACTTGA AATAATTAGT AACAAACCAT ACAAGATACC AAATACAGAA 
CTTATTCATC AGAGTTCCCC CTTGCTGAAG AGTGAGTTAG TGAAAGAAGT AACTAAATCT 
GTGGAAGAAG CTCAGCTTGC CCAAGAAGTC AAAGTAAACA TCATTCAGGA GGAATATCAA 
GAATATCGCC AAACAAAGGG AAGGAGCCTA TACACACTTC TAGAGGAGAT ACGGGACCTA 
GCTCTCCTGG ATGTTTCAAA CAATTATGGA ATATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_588616.1
CDS	222..3137
Translation	MQTACQAVQHQRGRRQYNKLRNLLKDARHDCILFANEFQQCCYLPRERGESMEKWQTRSIYNAAVWYYHHCQDRMPIVMVTEDEEAIQQYGSETEGVFVITFKNYLDNFWPDLKAAHELCDSILQSRRERENESQESHGKEYPEHLPLEVLEAGIKSGRYIQGILNVNKHRAQIEAFVRLQGASSKDSDLVSDILIHGMKARNRSIHGDVVVVELLPKNEWKGRTVALCENDCDDKASGESPSEPMPTGRVVGILQKNWRDYVVTFPSKEEVQSQGKNAQKILVTPWDYRIPKIRISTQQAETLQDFRVVVRIDSWESTSVYPNGHFVRVLGRIGDLEGEIATILVENSISVIPFSEAQMCEMPVNTPESPWKVSPEEEQKRKDLRKSHLVFSIDPKGCEDVDDTLSVRTLNNGNLELGVHIADVTHFVAPNSYIDIEARTRATTYYLADRRYDMLPSVLSADLCSLLGGVDRYAVSIMWELDKASYEIKKVWYGRTIIRSAYKLFYEAAQELLDGNLSVVDDIPEFKDLDEKSRQAKLEELVWAIGKLTDIARHVRAKRDGCGALELEGVEVCVQLDDKKNIHDLIPKQPLEVHETVAECMILANHWVAKKIWESFPHQALLRQHPPPHQEFFSELRECAKAKGFFIDTRSNKTLADSLDNANDPHDPIVNRLLRSMATQAMSNALYFSTGSCAEEEFHHYGLALDKYTHFTSPIRRYSDIVVHRLLMAAISKDKKMEIKGNLFSNKDLEELCRHINNRNQAAQHSQKQSTELFQCMYFKDKDPATEERCISDGVIYSIRTNGVLLFIPRFGIKGAAYLKNKDGLVISCGPDSCSEWKPGSLQRFQNKITSTTTDGESVTFHLFDHVTVRISIQASRCHSDTIRLEIISNKPYKIPNTELIHQSSPLLKSELVKEVTKSVEEAQLAQEVKVNIIQEEYQEYRQTKGRSLYTLLEEIRDLALLDVSNNYGI

Target ORF information:

RefSeq Version	NM_133375.4
Organism	Homo sapiens(human)
Definition	Homo sapiens DIS3 like exosome 3'-5' exoribonuclease (DIS3L), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_133375.4

ORF Insert Sequence:

ATGCAGACAG CTTGTCAAGC TGTGCAGCAT CAAAGAGGCA GGAGACAGTA TAACAAACTG 
CGAAACCTGC TGAAGGATGC GCGTCATGAT TGCATTCTCT TTGCTAATGA ATTCCAGCAA 
TGCTGCTATC TGCCACGGGA AAGAGGAGAG TCCATGGAGA AGTGGCAGAC CAGGAGCATA 
TACAACGCAG CTGTTTGGTA CTATCATCAC TGCCAGGACA GGATGCCAAT TGTTATGGTG 
ACAGAAGATG AAGAGGCAAT TCAGCAGTAT GGAAGTGAAA CAGAAGGAGT ATTCGTGATT 
ACTTTCAAGA ATTACCTGGA CAATTTCTGG CCTGATTTAA AAGCTGCCCA CGAGCTTTGT 
GATTCTATCC TTCAGTCTCG ACGGGAGAGA GAGAATGAGA GTCAGGAGAG CCATGGGAAG 
GAGTACCCAG AACATCTTCC CCTGGAAGTG TTAGAAGCTG GGATTAAATC TGGACGCTAT 
ATCCAGGGAA TTCTGAATGT CAACAAACAC AGAGCCCAAA TAGAAGCTTT TGTTCGACTT 
CAAGGAGCCA GCAGTAAAGA TTCAGATTTA GTCAGTGACA TCCTAATCCA CGGGATGAAG 
GCTCGAAACC GCTCAATTCA TGGAGATGTG GTAGTTGTGG AGCTGCTTCC TAAAAATGAA 
TGGAAAGGAA GAACCGTAGC CCTGTGTGAG AATGACTGTG ACGACAAGGC TTCGGGCGAG 
TCCCCAAGTG AGCCCATGCC TACAGGTCGA GTGGTGGGCA TACTTCAGAA GAACTGGCGG 
GATTATGTGG TGACATTTCC GTCCAAAGAA GAGGTCCAAT CTCAGGGCAA AAATGCTCAG 
AAAATCCTGG TTACACCTTG GGATTACAGA ATTCCCAAAA TTCGAATTAG CACTCAGCAA 
GCAGAAACCC TCCAGGACTT CAGGGTGGTC GTGCGCATCG ATTCCTGGGA GTCAACATCT 
GTGTATCCAA ATGGACATTT TGTGCGTGTT TTAGGAAGAA TCGGAGATCT GGAAGGGGAA 
ATTGCAACCA TCCTGGTGGA AAACAGTATT TCAGTTATTC CTTTCTCAGA AGCTCAGATG 
TGTGAGATGC CAGTAAACAC ACCAGAAAGT CCCTGGAAGG TGAGTCCTGA AGAGGAACAA 
AAACGTAAAG ACTTGAGGAA AAGCCATCTC GTATTCAGCA TTGACCCCAA AGGTTGTGAA 
GATGTGGATG ACACACTCTC AGTCAGAACC TTAAATAATG GCAACCTGGA ACTTGGGGTC 
CACATCGCAG ATGTAACACA CTTTGTGGCA CCAAATTCTT ACATTGATAT TGAAGCTAGA 
ACAAGGGCCA CCACTTATTA TCTAGCAGAT CGTCGCTATG ACATGCTGCC TTCCGTCCTC 
AGTGCAGATT TGTGTTCCCT TCTGGGAGGC GTTGATAGGT ATGCTGTAAG CATCATGTGG 
GAACTGGATA AAGCCTCTTA TGAAATTAAG AAAGTGTGGT ATGGCAGAAC CATTATTCGA 
TCAGCATACA AACTGTTCTA TGAAGCAGCC CAAGAACTAC TGGATGGAAA CTTAAGCGTT 
GTTGATGATA TTCCAGAATT CAAAGACTTG GATGAGAAGA GCAGACAAGC CAAGCTGGAG 
GAGTTGGTGT GGGCAATTGG AAAGCTGACC GACATAGCTC GCCATGTCAG AGCTAAACGA 
GACGGATGTG GTGCCCTGGA ACTGGAAGGG GTAGAGGTTT GCGTACAGCT AGATGACAAA 
AAGAACATTC ACGACCTCAT CCCCAAGCAG CCCCTGGAAG TCCACGAGAC AGTGGCTGAA 
TGCATGATCC TGGCCAACCA CTGGGTCGCC AAAAAGATCT GGGAGAGCTT CCCTCATCAG 
GCCTTGCTGC GCCAGCACCC TCCTCCACAC CAGGAGTTCT TTTCAGAACT CCGGGAATGT 
GCTAAAGCCA AAGGCTTCTT CATAGATACA CGGTCCAATA AAACACTGGC TGATTCTCTG 
GATAATGCGA ACGACCCCCA CGATCCCATT GTGAACAGGC TACTGCGCTC CATGGCCACG 
CAGGCCATGT CGAATGCTCT GTACTTCTCC ACCGGATCCT GTGCGGAGGA GGAGTTCCAT 
CATTACGGTC TTGCATTAGA TAAATATACC CACTTTACTT CTCCAATAAG AAGATATTCA 
GATATTGTAG TACACCGCTT GTTAATGGCA GCCATTTCAA AAGATAAGAA AATGGAAATT 
AAGGGAAATC TGTTCAGCAA CAAAGATCTT GAGGAATTAT GCAGACATAT CAACAACAGA 
AACCAAGCAG CACAGCATTC TCAGAAGCAG TCTACTGAGC TCTTCCAGTG CATGTACTTC 
AAAGACAAAG ACCCTGCCAC CGAGGAGCGT TGCATATCTG ACGGAGTTAT TTATTCAATT 
AGAACAAATG GTGTGCTTCT ATTTATACCA AGGTTTGGGA TTAAAGGTGC TGCTTATCTA 
AAAAATAAAG ATGGTTTAGT CATCTCATGT GGCCCAGATA GCTGTTCTGA ATGGAAACCA 
GGATCCCTTC AACGATTTCA AAACAAAATT ACCTCTACTA CAACAGATGG GGAATCTGTT 
ACGTTCCATT TGTTTGACCA TGTAACCGTA AGAATATCCA TACAGGCCTC ACGTTGCCAT 
TCTGATACAA TCAGACTTGA AATAATTAGT AACAAACCAT ACAAGATACC AAATACAGAA 
CTTATTCATC AGAGTTCCCC CTTGCTGAAG AGTGAGTTAG TGAAAGAAGT AACTAAATCT 
GTGGAAGAAG CTCAGCTTGC CCAAGAAGTC AAAGTAAACA TCATTCAGGA GGAATATCAA 
GAATATCGCC AAACAAAGGG AAGGAGCCTA TACACACTTC TAGAGGAGAT ACGGGACCTA 
GCTCTCCTGG ATGTTTCAAA CAATTATGGA ATATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

DIS3L ( NM_001323945.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001310874.1 Homo sapiens DIS3 like exosome 3'-5' exoribonuclease (DIS3L), transcript variant 11, mRNA.

Price & Availability↑

CloneID	OHu09544
Clone ID Related Accession (Same CDS sequence)	NM_001323945.2 , XM_005254147.3 , XM_005254145.2 , NM_001323936.2 , NM_133375.5 , NM_133375.4 , NM_001323945.1 , NM_001323936.1 , NM_133375.3
Accession Version	NM_001323945.1	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2916bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2018-12-04
Organism	Homo sapiens(human)
Product	DIS3-like exonuclease 1 isoform 2
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AC055855.9. On Apr 23, 2016 this sequence version replaced XM_005254145.2. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. ##Evidence-Data-START## Transcript exon combination :: SRR1803615.128867.1, SRR1803614.277865.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1966682, SAMEA1968189 [ECO:0000348] ##Evidence-Data-END##

ATGCAGACAG CTTGTCAAGC TGTGCAGCAT CAAAGAGGCA GGAGACAGTA TAACAAACTG 
CGAAACCTGC TGAAGGATGC GCGTCATGAT TGCATTCTCT TTGCTAATGA ATTCCAGCAA 
TGCTGCTATC TGCCACGGGA AAGAGGAGAG TCCATGGAGA AGTGGCAGAC CAGGAGCATA 
TACAACGCAG CTGTTTGGTA CTATCATCAC TGCCAGGACA GGATGCCAAT TGTTATGGTG 
ACAGAAGATG AAGAGGCAAT TCAGCAGTAT GGAAGTGAAA CAGAAGGAGT ATTCGTGATT 
ACTTTCAAGA ATTACCTGGA CAATTTCTGG CCTGATTTAA AAGCTGCCCA CGAGCTTTGT 
GATTCTATCC TTCAGTCTCG ACGGGAGAGA GAGAATGAGA GTCAGGAGAG CCATGGGAAG 
GAGTACCCAG AACATCTTCC CCTGGAAGTG TTAGAAGCTG GGATTAAATC TGGACGCTAT 
ATCCAGGGAA TTCTGAATGT CAACAAACAC AGAGCCCAAA TAGAAGCTTT TGTTCGACTT 
CAAGGAGCCA GCAGTAAAGA TTCAGATTTA GTCAGTGACA TCCTAATCCA CGGGATGAAG 
GCTCGAAACC GCTCAATTCA TGGAGATGTG GTAGTTGTGG AGCTGCTTCC TAAAAATGAA 
TGGAAAGGAA GAACCGTAGC CCTGTGTGAG AATGACTGTG ACGACAAGGC TTCGGGCGAG 
TCCCCAAGTG AGCCCATGCC TACAGGTCGA GTGGTGGGCA TACTTCAGAA GAACTGGCGG 
GATTATGTGG TGACATTTCC GTCCAAAGAA GAGGTCCAAT CTCAGGGCAA AAATGCTCAG 
AAAATCCTGG TTACACCTTG GGATTACAGA ATTCCCAAAA TTCGAATTAG CACTCAGCAA 
GCAGAAACCC TCCAGGACTT CAGGGTGGTC GTGCGCATCG ATTCCTGGGA GTCAACATCT 
GTGTATCCAA ATGGACATTT TGTGCGTGTT TTAGGAAGAA TCGGAGATCT GGAAGGGGAA 
ATTGCAACCA TCCTGGTGGA AAACAGTATT TCAGTTATTC CTTTCTCAGA AGCTCAGATG 
TGTGAGATGC CAGTAAACAC ACCAGAAAGT CCCTGGAAGG TGAGTCCTGA AGAGGAACAA 
AAACGTAAAG ACTTGAGGAA AAGCCATCTC GTATTCAGCA TTGACCCCAA AGGTTGTGAA 
GATGTGGATG ACACACTCTC AGTCAGAACC TTAAATAATG GCAACCTGGA ACTTGGGGTC 
CACATCGCAG ATGTAACACA CTTTGTGGCA CCAAATTCTT ACATTGATAT TGAAGCTAGA 
ACAAGGGCCA CCACTTATTA TCTAGCAGAT CGTCGCTATG ACATGCTGCC TTCCGTCCTC 
AGTGCAGATT TGTGTTCCCT TCTGGGAGGC GTTGATAGGT ATGCTGTAAG CATCATGTGG 
GAACTGGATA AAGCCTCTTA TGAAATTAAG AAAGTGTGGT ATGGCAGAAC CATTATTCGA 
TCAGCATACA AACTGTTCTA TGAAGCAGCC CAAGAACTAC TGGATGGAAA CTTAAGCGTT 
GTTGATGATA TTCCAGAATT CAAAGACTTG GATGAGAAGA GCAGACAAGC CAAGCTGGAG 
GAGTTGGTGT GGGCAATTGG AAAGCTGACC GACATAGCTC GCCATGTCAG AGCTAAACGA 
GACGGATGTG GTGCCCTGGA ACTGGAAGGG GTAGAGGTTT GCGTACAGCT AGATGACAAA 
AAGAACATTC ACGACCTCAT CCCCAAGCAG CCCCTGGAAG TCCACGAGAC AGTGGCTGAA 
TGCATGATCC TGGCCAACCA CTGGGTCGCC AAAAAGATCT GGGAGAGCTT CCCTCATCAG 
GCCTTGCTGC GCCAGCACCC TCCTCCACAC CAGGAGTTCT TTTCAGAACT CCGGGAATGT 
GCTAAAGCCA AAGGCTTCTT CATAGATACA CGGTCCAATA AAACACTGGC TGATTCTCTG 
GATAATGCGA ACGACCCCCA CGATCCCATT GTGAACAGGC TACTGCGCTC CATGGCCACG 
CAGGCCATGT CGAATGCTCT GTACTTCTCC ACCGGATCCT GTGCGGAGGA GGAGTTCCAT 
CATTACGGTC TTGCATTAGA TAAATATACC CACTTTACTT CTCCAATAAG AAGATATTCA 
GATATTGTAG TACACCGCTT GTTAATGGCA GCCATTTCAA AAGATAAGAA AATGGAAATT 
AAGGGAAATC TGTTCAGCAA CAAAGATCTT GAGGAATTAT GCAGACATAT CAACAACAGA 
AACCAAGCAG CACAGCATTC TCAGAAGCAG TCTACTGAGC TCTTCCAGTG CATGTACTTC 
AAAGACAAAG ACCCTGCCAC CGAGGAGCGT TGCATATCTG ACGGAGTTAT TTATTCAATT 
AGAACAAATG GTGTGCTTCT ATTTATACCA AGGTTTGGGA TTAAAGGTGC TGCTTATCTA 
AAAAATAAAG ATGGTTTAGT CATCTCATGT GGCCCAGATA GCTGTTCTGA ATGGAAACCA 
GGATCCCTTC AACGATTTCA AAACAAAATT ACCTCTACTA CAACAGATGG GGAATCTGTT 
ACGTTCCATT TGTTTGACCA TGTAACCGTA AGAATATCCA TACAGGCCTC ACGTTGCCAT 
TCTGATACAA TCAGACTTGA AATAATTAGT AACAAACCAT ACAAGATACC AAATACAGAA 
CTTATTCATC AGAGTTCCCC CTTGCTGAAG AGTGAGTTAG TGAAAGAAGT AACTAAATCT 
GTGGAAGAAG CTCAGCTTGC CCAAGAAGTC AAAGTAAACA TCATTCAGGA GGAATATCAA 
GAATATCGCC AAACAAAGGG AAGGAGCCTA TACACACTTC TAGAGGAGAT ACGGGACCTA 
GCTCTCCTGG ATGTTTCAAA CAATTATGGA ATATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001310874.1
CDS	740..3655
Translation	MQTACQAVQHQRGRRQYNKLRNLLKDARHDCILFANEFQQCCYLPRERGESMEKWQTRSIYNAAVWYYHHCQDRMPIVMVTEDEEAIQQYGSETEGVFVITFKNYLDNFWPDLKAAHELCDSILQSRRERENESQESHGKEYPEHLPLEVLEAGIKSGRYIQGILNVNKHRAQIEAFVRLQGASSKDSDLVSDILIHGMKARNRSIHGDVVVVELLPKNEWKGRTVALCENDCDDKASGESPSEPMPTGRVVGILQKNWRDYVVTFPSKEEVQSQGKNAQKILVTPWDYRIPKIRISTQQAETLQDFRVVVRIDSWESTSVYPNGHFVRVLGRIGDLEGEIATILVENSISVIPFSEAQMCEMPVNTPESPWKVSPEEEQKRKDLRKSHLVFSIDPKGCEDVDDTLSVRTLNNGNLELGVHIADVTHFVAPNSYIDIEARTRATTYYLADRRYDMLPSVLSADLCSLLGGVDRYAVSIMWELDKASYEIKKVWYGRTIIRSAYKLFYEAAQELLDGNLSVVDDIPEFKDLDEKSRQAKLEELVWAIGKLTDIARHVRAKRDGCGALELEGVEVCVQLDDKKNIHDLIPKQPLEVHETVAECMILANHWVAKKIWESFPHQALLRQHPPPHQEFFSELRECAKAKGFFIDTRSNKTLADSLDNANDPHDPIVNRLLRSMATQAMSNALYFSTGSCAEEEFHHYGLALDKYTHFTSPIRRYSDIVVHRLLMAAISKDKKMEIKGNLFSNKDLEELCRHINNRNQAAQHSQKQSTELFQCMYFKDKDPATEERCISDGVIYSIRTNGVLLFIPRFGIKGAAYLKNKDGLVISCGPDSCSEWKPGSLQRFQNKITSTTTDGESVTFHLFDHVTVRISIQASRCHSDTIRLEIISNKPYKIPNTELIHQSSPLLKSELVKEVTKSVEEAQLAQEVKVNIIQEEYQEYRQTKGRSLYTLLEEIRDLALLDVSNNYGI

Target ORF information:

RefSeq Version	NM_001323945.1
Organism	Homo sapiens(human)
Definition	Homo sapiens DIS3 like exosome 3'-5' exoribonuclease (DIS3L), transcript variant 11, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001323945.1

ORF Insert Sequence:

ATGCAGACAG CTTGTCAAGC TGTGCAGCAT CAAAGAGGCA GGAGACAGTA TAACAAACTG 
CGAAACCTGC TGAAGGATGC GCGTCATGAT TGCATTCTCT TTGCTAATGA ATTCCAGCAA 
TGCTGCTATC TGCCACGGGA AAGAGGAGAG TCCATGGAGA AGTGGCAGAC CAGGAGCATA 
TACAACGCAG CTGTTTGGTA CTATCATCAC TGCCAGGACA GGATGCCAAT TGTTATGGTG 
ACAGAAGATG AAGAGGCAAT TCAGCAGTAT GGAAGTGAAA CAGAAGGAGT ATTCGTGATT 
ACTTTCAAGA ATTACCTGGA CAATTTCTGG CCTGATTTAA AAGCTGCCCA CGAGCTTTGT 
GATTCTATCC TTCAGTCTCG ACGGGAGAGA GAGAATGAGA GTCAGGAGAG CCATGGGAAG 
GAGTACCCAG AACATCTTCC CCTGGAAGTG TTAGAAGCTG GGATTAAATC TGGACGCTAT 
ATCCAGGGAA TTCTGAATGT CAACAAACAC AGAGCCCAAA TAGAAGCTTT TGTTCGACTT 
CAAGGAGCCA GCAGTAAAGA TTCAGATTTA GTCAGTGACA TCCTAATCCA CGGGATGAAG 
GCTCGAAACC GCTCAATTCA TGGAGATGTG GTAGTTGTGG AGCTGCTTCC TAAAAATGAA 
TGGAAAGGAA GAACCGTAGC CCTGTGTGAG AATGACTGTG ACGACAAGGC TTCGGGCGAG 
TCCCCAAGTG AGCCCATGCC TACAGGTCGA GTGGTGGGCA TACTTCAGAA GAACTGGCGG 
GATTATGTGG TGACATTTCC GTCCAAAGAA GAGGTCCAAT CTCAGGGCAA AAATGCTCAG 
AAAATCCTGG TTACACCTTG GGATTACAGA ATTCCCAAAA TTCGAATTAG CACTCAGCAA 
GCAGAAACCC TCCAGGACTT CAGGGTGGTC GTGCGCATCG ATTCCTGGGA GTCAACATCT 
GTGTATCCAA ATGGACATTT TGTGCGTGTT TTAGGAAGAA TCGGAGATCT GGAAGGGGAA 
ATTGCAACCA TCCTGGTGGA AAACAGTATT TCAGTTATTC CTTTCTCAGA AGCTCAGATG 
TGTGAGATGC CAGTAAACAC ACCAGAAAGT CCCTGGAAGG TGAGTCCTGA AGAGGAACAA 
AAACGTAAAG ACTTGAGGAA AAGCCATCTC GTATTCAGCA TTGACCCCAA AGGTTGTGAA 
GATGTGGATG ACACACTCTC AGTCAGAACC TTAAATAATG GCAACCTGGA ACTTGGGGTC 
CACATCGCAG ATGTAACACA CTTTGTGGCA CCAAATTCTT ACATTGATAT TGAAGCTAGA 
ACAAGGGCCA CCACTTATTA TCTAGCAGAT CGTCGCTATG ACATGCTGCC TTCCGTCCTC 
AGTGCAGATT TGTGTTCCCT TCTGGGAGGC GTTGATAGGT ATGCTGTAAG CATCATGTGG 
GAACTGGATA AAGCCTCTTA TGAAATTAAG AAAGTGTGGT ATGGCAGAAC CATTATTCGA 
TCAGCATACA AACTGTTCTA TGAAGCAGCC CAAGAACTAC TGGATGGAAA CTTAAGCGTT 
GTTGATGATA TTCCAGAATT CAAAGACTTG GATGAGAAGA GCAGACAAGC CAAGCTGGAG 
GAGTTGGTGT GGGCAATTGG AAAGCTGACC GACATAGCTC GCCATGTCAG AGCTAAACGA 
GACGGATGTG GTGCCCTGGA ACTGGAAGGG GTAGAGGTTT GCGTACAGCT AGATGACAAA 
AAGAACATTC ACGACCTCAT CCCCAAGCAG CCCCTGGAAG TCCACGAGAC AGTGGCTGAA 
TGCATGATCC TGGCCAACCA CTGGGTCGCC AAAAAGATCT GGGAGAGCTT CCCTCATCAG 
GCCTTGCTGC GCCAGCACCC TCCTCCACAC CAGGAGTTCT TTTCAGAACT CCGGGAATGT 
GCTAAAGCCA AAGGCTTCTT CATAGATACA CGGTCCAATA AAACACTGGC TGATTCTCTG 
GATAATGCGA ACGACCCCCA CGATCCCATT GTGAACAGGC TACTGCGCTC CATGGCCACG 
CAGGCCATGT CGAATGCTCT GTACTTCTCC ACCGGATCCT GTGCGGAGGA GGAGTTCCAT 
CATTACGGTC TTGCATTAGA TAAATATACC CACTTTACTT CTCCAATAAG AAGATATTCA 
GATATTGTAG TACACCGCTT GTTAATGGCA GCCATTTCAA AAGATAAGAA AATGGAAATT 
AAGGGAAATC TGTTCAGCAA CAAAGATCTT GAGGAATTAT GCAGACATAT CAACAACAGA 
AACCAAGCAG CACAGCATTC TCAGAAGCAG TCTACTGAGC TCTTCCAGTG CATGTACTTC 
AAAGACAAAG ACCCTGCCAC CGAGGAGCGT TGCATATCTG ACGGAGTTAT TTATTCAATT 
AGAACAAATG GTGTGCTTCT ATTTATACCA AGGTTTGGGA TTAAAGGTGC TGCTTATCTA 
AAAAATAAAG ATGGTTTAGT CATCTCATGT GGCCCAGATA GCTGTTCTGA ATGGAAACCA 
GGATCCCTTC AACGATTTCA AAACAAAATT ACCTCTACTA CAACAGATGG GGAATCTGTT 
ACGTTCCATT TGTTTGACCA TGTAACCGTA AGAATATCCA TACAGGCCTC ACGTTGCCAT 
TCTGATACAA TCAGACTTGA AATAATTAGT AACAAACCAT ACAAGATACC AAATACAGAA 
CTTATTCATC AGAGTTCCCC CTTGCTGAAG AGTGAGTTAG TGAAAGAAGT AACTAAATCT 
GTGGAAGAAG CTCAGCTTGC CCAAGAAGTC AAAGTAAACA TCATTCAGGA GGAATATCAA 
GAATATCGCC AAACAAAGGG AAGGAGCCTA TACACACTTC TAGAGGAGAT ACGGGACCTA 
GCTCTCCTGG ATGTTTCAAA CAATTATGGA ATATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

DIS3L ( NM_001323936.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001310865.1 Homo sapiens DIS3 like exosome 3'-5' exoribonuclease (DIS3L), transcript variant 3, mRNA.

Price & Availability↑

CloneID	OHu09544
Clone ID Related Accession (Same CDS sequence)	NM_001323945.2 , XM_005254147.3 , XM_005254145.2 , NM_001323936.2 , NM_133375.5 , NM_133375.4 , NM_001323945.1 , NM_001323936.1 , NM_133375.3
Accession Version	NM_001323936.1	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2916bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2018-12-04
Organism	Homo sapiens(human)
Product	DIS3-like exonuclease 1 isoform 2
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AC055855.9. On Apr 23, 2016 this sequence version replaced XM_005254147.3. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. ##Evidence-Data-START## Transcript exon combination :: SRR1660807.225743.1, SRR1660803.119786.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1968540 [ECO:0000348] ##Evidence-Data-END##

ATGCAGACAG CTTGTCAAGC TGTGCAGCAT CAAAGAGGCA GGAGACAGTA TAACAAACTG 
CGAAACCTGC TGAAGGATGC GCGTCATGAT TGCATTCTCT TTGCTAATGA ATTCCAGCAA 
TGCTGCTATC TGCCACGGGA AAGAGGAGAG TCCATGGAGA AGTGGCAGAC CAGGAGCATA 
TACAACGCAG CTGTTTGGTA CTATCATCAC TGCCAGGACA GGATGCCAAT TGTTATGGTG 
ACAGAAGATG AAGAGGCAAT TCAGCAGTAT GGAAGTGAAA CAGAAGGAGT ATTCGTGATT 
ACTTTCAAGA ATTACCTGGA CAATTTCTGG CCTGATTTAA AAGCTGCCCA CGAGCTTTGT 
GATTCTATCC TTCAGTCTCG ACGGGAGAGA GAGAATGAGA GTCAGGAGAG CCATGGGAAG 
GAGTACCCAG AACATCTTCC CCTGGAAGTG TTAGAAGCTG GGATTAAATC TGGACGCTAT 
ATCCAGGGAA TTCTGAATGT CAACAAACAC AGAGCCCAAA TAGAAGCTTT TGTTCGACTT 
CAAGGAGCCA GCAGTAAAGA TTCAGATTTA GTCAGTGACA TCCTAATCCA CGGGATGAAG 
GCTCGAAACC GCTCAATTCA TGGAGATGTG GTAGTTGTGG AGCTGCTTCC TAAAAATGAA 
TGGAAAGGAA GAACCGTAGC CCTGTGTGAG AATGACTGTG ACGACAAGGC TTCGGGCGAG 
TCCCCAAGTG AGCCCATGCC TACAGGTCGA GTGGTGGGCA TACTTCAGAA GAACTGGCGG 
GATTATGTGG TGACATTTCC GTCCAAAGAA GAGGTCCAAT CTCAGGGCAA AAATGCTCAG 
AAAATCCTGG TTACACCTTG GGATTACAGA ATTCCCAAAA TTCGAATTAG CACTCAGCAA 
GCAGAAACCC TCCAGGACTT CAGGGTGGTC GTGCGCATCG ATTCCTGGGA GTCAACATCT 
GTGTATCCAA ATGGACATTT TGTGCGTGTT TTAGGAAGAA TCGGAGATCT GGAAGGGGAA 
ATTGCAACCA TCCTGGTGGA AAACAGTATT TCAGTTATTC CTTTCTCAGA AGCTCAGATG 
TGTGAGATGC CAGTAAACAC ACCAGAAAGT CCCTGGAAGG TGAGTCCTGA AGAGGAACAA 
AAACGTAAAG ACTTGAGGAA AAGCCATCTC GTATTCAGCA TTGACCCCAA AGGTTGTGAA 
GATGTGGATG ACACACTCTC AGTCAGAACC TTAAATAATG GCAACCTGGA ACTTGGGGTC 
CACATCGCAG ATGTAACACA CTTTGTGGCA CCAAATTCTT ACATTGATAT TGAAGCTAGA 
ACAAGGGCCA CCACTTATTA TCTAGCAGAT CGTCGCTATG ACATGCTGCC TTCCGTCCTC 
AGTGCAGATT TGTGTTCCCT TCTGGGAGGC GTTGATAGGT ATGCTGTAAG CATCATGTGG 
GAACTGGATA AAGCCTCTTA TGAAATTAAG AAAGTGTGGT ATGGCAGAAC CATTATTCGA 
TCAGCATACA AACTGTTCTA TGAAGCAGCC CAAGAACTAC TGGATGGAAA CTTAAGCGTT 
GTTGATGATA TTCCAGAATT CAAAGACTTG GATGAGAAGA GCAGACAAGC CAAGCTGGAG 
GAGTTGGTGT GGGCAATTGG AAAGCTGACC GACATAGCTC GCCATGTCAG AGCTAAACGA 
GACGGATGTG GTGCCCTGGA ACTGGAAGGG GTAGAGGTTT GCGTACAGCT AGATGACAAA 
AAGAACATTC ACGACCTCAT CCCCAAGCAG CCCCTGGAAG TCCACGAGAC AGTGGCTGAA 
TGCATGATCC TGGCCAACCA CTGGGTCGCC AAAAAGATCT GGGAGAGCTT CCCTCATCAG 
GCCTTGCTGC GCCAGCACCC TCCTCCACAC CAGGAGTTCT TTTCAGAACT CCGGGAATGT 
GCTAAAGCCA AAGGCTTCTT CATAGATACA CGGTCCAATA AAACACTGGC TGATTCTCTG 
GATAATGCGA ACGACCCCCA CGATCCCATT GTGAACAGGC TACTGCGCTC CATGGCCACG 
CAGGCCATGT CGAATGCTCT GTACTTCTCC ACCGGATCCT GTGCGGAGGA GGAGTTCCAT 
CATTACGGTC TTGCATTAGA TAAATATACC CACTTTACTT CTCCAATAAG AAGATATTCA 
GATATTGTAG TACACCGCTT GTTAATGGCA GCCATTTCAA AAGATAAGAA AATGGAAATT 
AAGGGAAATC TGTTCAGCAA CAAAGATCTT GAGGAATTAT GCAGACATAT CAACAACAGA 
AACCAAGCAG CACAGCATTC TCAGAAGCAG TCTACTGAGC TCTTCCAGTG CATGTACTTC 
AAAGACAAAG ACCCTGCCAC CGAGGAGCGT TGCATATCTG ACGGAGTTAT TTATTCAATT 
AGAACAAATG GTGTGCTTCT ATTTATACCA AGGTTTGGGA TTAAAGGTGC TGCTTATCTA 
AAAAATAAAG ATGGTTTAGT CATCTCATGT GGCCCAGATA GCTGTTCTGA ATGGAAACCA 
GGATCCCTTC AACGATTTCA AAACAAAATT ACCTCTACTA CAACAGATGG GGAATCTGTT 
ACGTTCCATT TGTTTGACCA TGTAACCGTA AGAATATCCA TACAGGCCTC ACGTTGCCAT 
TCTGATACAA TCAGACTTGA AATAATTAGT AACAAACCAT ACAAGATACC AAATACAGAA 
CTTATTCATC AGAGTTCCCC CTTGCTGAAG AGTGAGTTAG TGAAAGAAGT AACTAAATCT 
GTGGAAGAAG CTCAGCTTGC CCAAGAAGTC AAAGTAAACA TCATTCAGGA GGAATATCAA 
GAATATCGCC AAACAAAGGG AAGGAGCCTA TACACACTTC TAGAGGAGAT ACGGGACCTA 
GCTCTCCTGG ATGTTTCAAA CAATTATGGA ATATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001310865.1
CDS	191..3106
Translation	MQTACQAVQHQRGRRQYNKLRNLLKDARHDCILFANEFQQCCYLPRERGESMEKWQTRSIYNAAVWYYHHCQDRMPIVMVTEDEEAIQQYGSETEGVFVITFKNYLDNFWPDLKAAHELCDSILQSRRERENESQESHGKEYPEHLPLEVLEAGIKSGRYIQGILNVNKHRAQIEAFVRLQGASSKDSDLVSDILIHGMKARNRSIHGDVVVVELLPKNEWKGRTVALCENDCDDKASGESPSEPMPTGRVVGILQKNWRDYVVTFPSKEEVQSQGKNAQKILVTPWDYRIPKIRISTQQAETLQDFRVVVRIDSWESTSVYPNGHFVRVLGRIGDLEGEIATILVENSISVIPFSEAQMCEMPVNTPESPWKVSPEEEQKRKDLRKSHLVFSIDPKGCEDVDDTLSVRTLNNGNLELGVHIADVTHFVAPNSYIDIEARTRATTYYLADRRYDMLPSVLSADLCSLLGGVDRYAVSIMWELDKASYEIKKVWYGRTIIRSAYKLFYEAAQELLDGNLSVVDDIPEFKDLDEKSRQAKLEELVWAIGKLTDIARHVRAKRDGCGALELEGVEVCVQLDDKKNIHDLIPKQPLEVHETVAECMILANHWVAKKIWESFPHQALLRQHPPPHQEFFSELRECAKAKGFFIDTRSNKTLADSLDNANDPHDPIVNRLLRSMATQAMSNALYFSTGSCAEEEFHHYGLALDKYTHFTSPIRRYSDIVVHRLLMAAISKDKKMEIKGNLFSNKDLEELCRHINNRNQAAQHSQKQSTELFQCMYFKDKDPATEERCISDGVIYSIRTNGVLLFIPRFGIKGAAYLKNKDGLVISCGPDSCSEWKPGSLQRFQNKITSTTTDGESVTFHLFDHVTVRISIQASRCHSDTIRLEIISNKPYKIPNTELIHQSSPLLKSELVKEVTKSVEEAQLAQEVKVNIIQEEYQEYRQTKGRSLYTLLEEIRDLALLDVSNNYGI

Target ORF information:

RefSeq Version	NM_001323936.1
Organism	Homo sapiens(human)
Definition	Homo sapiens DIS3 like exosome 3'-5' exoribonuclease (DIS3L), transcript variant 3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001323936.1

ORF Insert Sequence:

ATGCAGACAG CTTGTCAAGC TGTGCAGCAT CAAAGAGGCA GGAGACAGTA TAACAAACTG 
CGAAACCTGC TGAAGGATGC GCGTCATGAT TGCATTCTCT TTGCTAATGA ATTCCAGCAA 
TGCTGCTATC TGCCACGGGA AAGAGGAGAG TCCATGGAGA AGTGGCAGAC CAGGAGCATA 
TACAACGCAG CTGTTTGGTA CTATCATCAC TGCCAGGACA GGATGCCAAT TGTTATGGTG 
ACAGAAGATG AAGAGGCAAT TCAGCAGTAT GGAAGTGAAA CAGAAGGAGT ATTCGTGATT 
ACTTTCAAGA ATTACCTGGA CAATTTCTGG CCTGATTTAA AAGCTGCCCA CGAGCTTTGT 
GATTCTATCC TTCAGTCTCG ACGGGAGAGA GAGAATGAGA GTCAGGAGAG CCATGGGAAG 
GAGTACCCAG AACATCTTCC CCTGGAAGTG TTAGAAGCTG GGATTAAATC TGGACGCTAT 
ATCCAGGGAA TTCTGAATGT CAACAAACAC AGAGCCCAAA TAGAAGCTTT TGTTCGACTT 
CAAGGAGCCA GCAGTAAAGA TTCAGATTTA GTCAGTGACA TCCTAATCCA CGGGATGAAG 
GCTCGAAACC GCTCAATTCA TGGAGATGTG GTAGTTGTGG AGCTGCTTCC TAAAAATGAA 
TGGAAAGGAA GAACCGTAGC CCTGTGTGAG AATGACTGTG ACGACAAGGC TTCGGGCGAG 
TCCCCAAGTG AGCCCATGCC TACAGGTCGA GTGGTGGGCA TACTTCAGAA GAACTGGCGG 
GATTATGTGG TGACATTTCC GTCCAAAGAA GAGGTCCAAT CTCAGGGCAA AAATGCTCAG 
AAAATCCTGG TTACACCTTG GGATTACAGA ATTCCCAAAA TTCGAATTAG CACTCAGCAA 
GCAGAAACCC TCCAGGACTT CAGGGTGGTC GTGCGCATCG ATTCCTGGGA GTCAACATCT 
GTGTATCCAA ATGGACATTT TGTGCGTGTT TTAGGAAGAA TCGGAGATCT GGAAGGGGAA 
ATTGCAACCA TCCTGGTGGA AAACAGTATT TCAGTTATTC CTTTCTCAGA AGCTCAGATG 
TGTGAGATGC CAGTAAACAC ACCAGAAAGT CCCTGGAAGG TGAGTCCTGA AGAGGAACAA 
AAACGTAAAG ACTTGAGGAA AAGCCATCTC GTATTCAGCA TTGACCCCAA AGGTTGTGAA 
GATGTGGATG ACACACTCTC AGTCAGAACC TTAAATAATG GCAACCTGGA ACTTGGGGTC 
CACATCGCAG ATGTAACACA CTTTGTGGCA CCAAATTCTT ACATTGATAT TGAAGCTAGA 
ACAAGGGCCA CCACTTATTA TCTAGCAGAT CGTCGCTATG ACATGCTGCC TTCCGTCCTC 
AGTGCAGATT TGTGTTCCCT TCTGGGAGGC GTTGATAGGT ATGCTGTAAG CATCATGTGG 
GAACTGGATA AAGCCTCTTA TGAAATTAAG AAAGTGTGGT ATGGCAGAAC CATTATTCGA 
TCAGCATACA AACTGTTCTA TGAAGCAGCC CAAGAACTAC TGGATGGAAA CTTAAGCGTT 
GTTGATGATA TTCCAGAATT CAAAGACTTG GATGAGAAGA GCAGACAAGC CAAGCTGGAG 
GAGTTGGTGT GGGCAATTGG AAAGCTGACC GACATAGCTC GCCATGTCAG AGCTAAACGA 
GACGGATGTG GTGCCCTGGA ACTGGAAGGG GTAGAGGTTT GCGTACAGCT AGATGACAAA 
AAGAACATTC ACGACCTCAT CCCCAAGCAG CCCCTGGAAG TCCACGAGAC AGTGGCTGAA 
TGCATGATCC TGGCCAACCA CTGGGTCGCC AAAAAGATCT GGGAGAGCTT CCCTCATCAG 
GCCTTGCTGC GCCAGCACCC TCCTCCACAC CAGGAGTTCT TTTCAGAACT CCGGGAATGT 
GCTAAAGCCA AAGGCTTCTT CATAGATACA CGGTCCAATA AAACACTGGC TGATTCTCTG 
GATAATGCGA ACGACCCCCA CGATCCCATT GTGAACAGGC TACTGCGCTC CATGGCCACG 
CAGGCCATGT CGAATGCTCT GTACTTCTCC ACCGGATCCT GTGCGGAGGA GGAGTTCCAT 
CATTACGGTC TTGCATTAGA TAAATATACC CACTTTACTT CTCCAATAAG AAGATATTCA 
GATATTGTAG TACACCGCTT GTTAATGGCA GCCATTTCAA AAGATAAGAA AATGGAAATT 
AAGGGAAATC TGTTCAGCAA CAAAGATCTT GAGGAATTAT GCAGACATAT CAACAACAGA 
AACCAAGCAG CACAGCATTC TCAGAAGCAG TCTACTGAGC TCTTCCAGTG CATGTACTTC 
AAAGACAAAG ACCCTGCCAC CGAGGAGCGT TGCATATCTG ACGGAGTTAT TTATTCAATT 
AGAACAAATG GTGTGCTTCT ATTTATACCA AGGTTTGGGA TTAAAGGTGC TGCTTATCTA 
AAAAATAAAG ATGGTTTAGT CATCTCATGT GGCCCAGATA GCTGTTCTGA ATGGAAACCA 
GGATCCCTTC AACGATTTCA AAACAAAATT ACCTCTACTA CAACAGATGG GGAATCTGTT 
ACGTTCCATT TGTTTGACCA TGTAACCGTA AGAATATCCA TACAGGCCTC ACGTTGCCAT 
TCTGATACAA TCAGACTTGA AATAATTAGT AACAAACCAT ACAAGATACC AAATACAGAA 
CTTATTCATC AGAGTTCCCC CTTGCTGAAG AGTGAGTTAG TGAAAGAAGT AACTAAATCT 
GTGGAAGAAG CTCAGCTTGC CCAAGAAGTC AAAGTAAACA TCATTCAGGA GGAATATCAA 
GAATATCGCC AAACAAAGGG AAGGAGCCTA TACACACTTC TAGAGGAGAT ACGGGACCTA 
GCTCTCCTGG ATGTTTCAAA CAATTATGGA ATATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

DIS3L ( NM_133375.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_588616.1 Homo sapiens DIS3 like exosome 3'-5' exoribonuclease (DIS3L), transcript variant 2, mRNA.

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CloneID	OHu09544
Clone ID Related Accession (Same CDS sequence)	NM_001323945.2 , XM_005254147.3 , XM_005254145.2 , NM_001323936.2 , NM_133375.5 , NM_133375.4 , NM_001323945.1 , NM_001323936.1 , NM_133375.3
Accession Version	NM_133375.3	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2916bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2015-03-14
Organism	Homo sapiens(Human)
Product	DIS3-like exonuclease 1 isoform 2
Comment

ATGCAGACAG CTTGTCAAGC TGTGCAGCAT CAAAGAGGCA GGAGACAGTA TAACAAACTG 
CGAAACCTGC TGAAGGATGC GCGTCATGAT TGCATTCTCT TTGCTAATGA ATTCCAGCAA 
TGCTGCTATC TGCCACGGGA AAGAGGAGAG TCCATGGAGA AGTGGCAGAC CAGGAGCATA 
TACAACGCAG CTGTTTGGTA CTATCATCAC TGCCAGGACA GGATGCCAAT TGTTATGGTG 
ACAGAAGATG AAGAGGCAAT TCAGCAGTAT GGAAGTGAAA CAGAAGGAGT ATTCGTGATT 
ACTTTCAAGA ATTACCTGGA CAATTTCTGG CCTGATTTAA AAGCTGCCCA CGAGCTTTGT 
GATTCTATCC TTCAGTCTCG ACGGGAGAGA GAGAATGAGA GTCAGGAGAG CCATGGGAAG 
GAGTACCCAG AACATCTTCC CCTGGAAGTG TTAGAAGCTG GGATTAAATC TGGACGCTAT 
ATCCAGGGAA TTCTGAATGT CAACAAACAC AGAGCCCAAA TAGAAGCTTT TGTTCGACTT 
CAAGGAGCCA GCAGTAAAGA TTCAGATTTA GTCAGTGACA TCCTAATCCA CGGGATGAAG 
GCTCGAAACC GCTCAATTCA TGGAGATGTG GTAGTTGTGG AGCTGCTTCC TAAAAATGAA 
TGGAAAGGAA GAACCGTAGC CCTGTGTGAG AATGACTGTG ACGACAAGGC TTCGGGCGAG 
TCCCCAAGTG AGCCCATGCC TACAGGTCGA GTGGTGGGCA TACTTCAGAA GAACTGGCGG 
GATTATGTGG TGACATTTCC GTCCAAAGAA GAGGTCCAAT CTCAGGGCAA AAATGCTCAG 
AAAATCCTGG TTACACCTTG GGATTACAGA ATTCCCAAAA TTCGAATTAG CACTCAGCAA 
GCAGAAACCC TCCAGGACTT CAGGGTGGTC GTGCGCATCG ATTCCTGGGA GTCAACATCT 
GTGTATCCAA ATGGACATTT TGTGCGTGTT TTAGGAAGAA TCGGAGATCT GGAAGGGGAA 
ATTGCAACCA TCCTGGTGGA AAACAGTATT TCAGTTATTC CTTTCTCAGA AGCTCAGATG 
TGTGAGATGC CAGTAAACAC ACCAGAAAGT CCCTGGAAGG TGAGTCCTGA AGAGGAACAA 
AAACGTAAAG ACTTGAGGAA AAGCCATCTC GTATTCAGCA TTGACCCCAA AGGTTGTGAA 
GATGTGGATG ACACACTCTC AGTCAGAACC TTAAATAATG GCAACCTGGA ACTTGGGGTC 
CACATCGCAG ATGTAACACA CTTTGTGGCA CCAAATTCTT ACATTGATAT TGAAGCTAGA 
ACAAGGGCCA CCACTTATTA TCTAGCAGAT CGTCGCTATG ACATGCTGCC TTCCGTCCTC 
AGTGCAGATT TGTGTTCCCT TCTGGGAGGC GTTGATAGGT ATGCTGTAAG CATCATGTGG 
GAACTGGATA AAGCCTCTTA TGAAATTAAG AAAGTGTGGT ATGGCAGAAC CATTATTCGA 
TCAGCATACA AACTGTTCTA TGAAGCAGCC CAAGAACTAC TGGATGGAAA CTTAAGCGTT 
GTTGATGATA TTCCAGAATT CAAAGACTTG GATGAGAAGA GCAGACAAGC CAAGCTGGAG 
GAGTTGGTGT GGGCAATTGG AAAGCTGACC GACATAGCTC GCCATGTCAG AGCTAAACGA 
GACGGATGTG GTGCCCTGGA ACTGGAAGGG GTAGAGGTTT GCGTACAGCT AGATGACAAA 
AAGAACATTC ACGACCTCAT CCCCAAGCAG CCCCTGGAAG TCCACGAGAC AGTGGCTGAA 
TGCATGATCC TGGCCAACCA CTGGGTCGCC AAAAAGATCT GGGAGAGCTT CCCTCATCAG 
GCCTTGCTGC GCCAGCACCC TCCTCCACAC CAGGAGTTCT TTTCAGAACT CCGGGAATGT 
GCTAAAGCCA AAGGCTTCTT CATAGATACA CGGTCCAATA AAACACTGGC TGATTCTCTG 
GATAATGCGA ACGACCCCCA CGATCCCATT GTGAACAGGC TACTGCGCTC CATGGCCACG 
CAGGCCATGT CGAATGCTCT GTACTTCTCC ACCGGATCCT GTGCGGAGGA GGAGTTCCAT 
CATTACGGTC TTGCATTAGA TAAATATACC CACTTTACTT CTCCAATAAG AAGATATTCA 
GATATTGTAG TACACCGCTT GTTAATGGCA GCCATTTCAA AAGATAAGAA AATGGAAATT 
AAGGGAAATC TGTTCAGCAA CAAAGATCTT GAGGAATTAT GCAGACATAT CAACAACAGA 
AACCAAGCAG CACAGCATTC TCAGAAGCAG TCTACTGAGC TCTTCCAGTG CATGTACTTC 
AAAGACAAAG ACCCTGCCAC CGAGGAGCGT TGCATATCTG ACGGAGTTAT TTATTCAATT 
AGAACAAATG GTGTGCTTCT ATTTATACCA AGGTTTGGGA TTAAAGGTGC TGCTTATCTA 
AAAAATAAAG ATGGTTTAGT CATCTCATGT GGCCCAGATA GCTGTTCTGA ATGGAAACCA 
GGATCCCTTC AACGATTTCA AAACAAAATT ACCTCTACTA CAACAGATGG GGAATCTGTT 
ACGTTCCATT TGTTTGACCA TGTAACCGTA AGAATATCCA TACAGGCCTC ACGTTGCCAT 
TCTGATACAA TCAGACTTGA AATAATTAGT AACAAACCAT ACAAGATACC AAATACAGAA 
CTTATTCATC AGAGTTCCCC CTTGCTGAAG AGTGAGTTAG TGAAAGAAGT AACTAAATCT 
GTGGAAGAAG CTCAGCTTGC CCAAGAAGTC AAAGTAAACA TCATTCAGGA GGAATATCAA 
GAATATCGCC AAACAAAGGG AAGGAGCCTA TACACACTTC TAGAGGAGAT ACGGGACCTA 
GCTCTCCTGG ATGTTTCAAA CAATTATGGA ATATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq

NP_588616.1

Translation

MQTACQAVQHQRGRRQYNKLRNLLKDARHDCILFANEFQQCCYLPRERGESMEKWQTRSIYNAAVWYYHHCQDRMPIVMVTEDEEAIQQYGSETEGVFVITFKNYLDNFWPDLKAAHELCDSILQSRRERENESQESHGKEYPEHLPLEVLEAGIKSGRYIQGILNVNKHRAQIEAFVRLQGASSKDSDLVSDILIHGMKARNRSIHGDVVVVELLPKNEWKGRTVALCENDCDDKASGESPSEPMPTGRVVGILQKNWRDYVVTFPSKEEVQSQGKNAQKILVTPWDYRIPKIRISTQQAETLQDFRVVVRIDSWESTSVYPNGHFVRVLGRIGDLEGEIATILVENSISVIPFSEAQMCEMPVNTPESPWKVSPEEEQKRKDLRKSHLVFSIDPKGCEDVDDTLSVRTLNNGNLELGVHIADVTHFVAPNSYIDIEARTRATTYYLADRRYDMLPSVLSADLCSLLGGVDRYAVSIMWELDKASYEIKKVWYGRTIIRSAYKLFYEAAQELLDGNLSVVDDIPEFKDLDEKSRQAKLEELVWAIGKLTDIARHVRAKRDGCGALELEGVEVCVQLDDKKNIHDLIPKQPLEVHETVAECMILANHWVAKKIWESFPHQALLRQHPPPHQEFFSELRECAKAKGFFIDTRSNKTLADSLDNANDPHDPIVNRLLRSMATQAMSNALYFSTGSCAEEEFHHYGLALDKYTHFTSPIRRYSDIVVHRLLMAAISKDKKMEIKGNLFSNKDLEELCRHINNRNQAAQHSQKQSTELFQCMYFKDKDPATEERCISDGVIYSIRTNGVLLFIPRFGIKGAAYLKNKDGLVISCGPDSCSEWKPGSLQRFQNKITSTTTDGESVTFHLFDHVTVRISIQASRCHSDTIRLEIISNKPYKIPNTELIHQSSPLLKSELVKEVTKSVEEAQLAQEVKVNIIQEEYQEYRQTKGRSLYTLLEEIRDLALLDVSNNYGI

Target ORF information:

RefSeq Version	NM_133375.3
Organism	Homo sapiens(Human)
Definition	Homo sapiens DIS3 like exosome 3'-5' exoribonuclease (DIS3L), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_133375.3

ORF Insert Sequence:

ATGCAGACAG CTTGTCAAGC TGTGCAGCAT CAAAGAGGCA GGAGACAGTA TAACAAACTG 
CGAAACCTGC TGAAGGATGC GCGTCATGAT TGCATTCTCT TTGCTAATGA ATTCCAGCAA 
TGCTGCTATC TGCCACGGGA AAGAGGAGAG TCCATGGAGA AGTGGCAGAC CAGGAGCATA 
TACAACGCAG CTGTTTGGTA CTATCATCAC TGCCAGGACA GGATGCCAAT TGTTATGGTG 
ACAGAAGATG AAGAGGCAAT TCAGCAGTAT GGAAGTGAAA CAGAAGGAGT ATTCGTGATT 
ACTTTCAAGA ATTACCTGGA CAATTTCTGG CCTGATTTAA AAGCTGCCCA CGAGCTTTGT 
GATTCTATCC TTCAGTCTCG ACGGGAGAGA GAGAATGAGA GTCAGGAGAG CCATGGGAAG 
GAGTACCCAG AACATCTTCC CCTGGAAGTG TTAGAAGCTG GGATTAAATC TGGACGCTAT 
ATCCAGGGAA TTCTGAATGT CAACAAACAC AGAGCCCAAA TAGAAGCTTT TGTTCGACTT 
CAAGGAGCCA GCAGTAAAGA TTCAGATTTA GTCAGTGACA TCCTAATCCA CGGGATGAAG 
GCTCGAAACC GCTCAATTCA TGGAGATGTG GTAGTTGTGG AGCTGCTTCC TAAAAATGAA 
TGGAAAGGAA GAACCGTAGC CCTGTGTGAG AATGACTGTG ACGACAAGGC TTCGGGCGAG 
TCCCCAAGTG AGCCCATGCC TACAGGTCGA GTGGTGGGCA TACTTCAGAA GAACTGGCGG 
GATTATGTGG TGACATTTCC GTCCAAAGAA GAGGTCCAAT CTCAGGGCAA AAATGCTCAG 
AAAATCCTGG TTACACCTTG GGATTACAGA ATTCCCAAAA TTCGAATTAG CACTCAGCAA 
GCAGAAACCC TCCAGGACTT CAGGGTGGTC GTGCGCATCG ATTCCTGGGA GTCAACATCT 
GTGTATCCAA ATGGACATTT TGTGCGTGTT TTAGGAAGAA TCGGAGATCT GGAAGGGGAA 
ATTGCAACCA TCCTGGTGGA AAACAGTATT TCAGTTATTC CTTTCTCAGA AGCTCAGATG 
TGTGAGATGC CAGTAAACAC ACCAGAAAGT CCCTGGAAGG TGAGTCCTGA AGAGGAACAA 
AAACGTAAAG ACTTGAGGAA AAGCCATCTC GTATTCAGCA TTGACCCCAA AGGTTGTGAA 
GATGTGGATG ACACACTCTC AGTCAGAACC TTAAATAATG GCAACCTGGA ACTTGGGGTC 
CACATCGCAG ATGTAACACA CTTTGTGGCA CCAAATTCTT ACATTGATAT TGAAGCTAGA 
ACAAGGGCCA CCACTTATTA TCTAGCAGAT CGTCGCTATG ACATGCTGCC TTCCGTCCTC 
AGTGCAGATT TGTGTTCCCT TCTGGGAGGC GTTGATAGGT ATGCTGTAAG CATCATGTGG 
GAACTGGATA AAGCCTCTTA TGAAATTAAG AAAGTGTGGT ATGGCAGAAC CATTATTCGA 
TCAGCATACA AACTGTTCTA TGAAGCAGCC CAAGAACTAC TGGATGGAAA CTTAAGCGTT 
GTTGATGATA TTCCAGAATT CAAAGACTTG GATGAGAAGA GCAGACAAGC CAAGCTGGAG 
GAGTTGGTGT GGGCAATTGG AAAGCTGACC GACATAGCTC GCCATGTCAG AGCTAAACGA 
GACGGATGTG GTGCCCTGGA ACTGGAAGGG GTAGAGGTTT GCGTACAGCT AGATGACAAA 
AAGAACATTC ACGACCTCAT CCCCAAGCAG CCCCTGGAAG TCCACGAGAC AGTGGCTGAA 
TGCATGATCC TGGCCAACCA CTGGGTCGCC AAAAAGATCT GGGAGAGCTT CCCTCATCAG 
GCCTTGCTGC GCCAGCACCC TCCTCCACAC CAGGAGTTCT TTTCAGAACT CCGGGAATGT 
GCTAAAGCCA AAGGCTTCTT CATAGATACA CGGTCCAATA AAACACTGGC TGATTCTCTG 
GATAATGCGA ACGACCCCCA CGATCCCATT GTGAACAGGC TACTGCGCTC CATGGCCACG 
CAGGCCATGT CGAATGCTCT GTACTTCTCC ACCGGATCCT GTGCGGAGGA GGAGTTCCAT 
CATTACGGTC TTGCATTAGA TAAATATACC CACTTTACTT CTCCAATAAG AAGATATTCA 
GATATTGTAG TACACCGCTT GTTAATGGCA GCCATTTCAA AAGATAAGAA AATGGAAATT 
AAGGGAAATC TGTTCAGCAA CAAAGATCTT GAGGAATTAT GCAGACATAT CAACAACAGA 
AACCAAGCAG CACAGCATTC TCAGAAGCAG TCTACTGAGC TCTTCCAGTG CATGTACTTC 
AAAGACAAAG ACCCTGCCAC CGAGGAGCGT TGCATATCTG ACGGAGTTAT TTATTCAATT 
AGAACAAATG GTGTGCTTCT ATTTATACCA AGGTTTGGGA TTAAAGGTGC TGCTTATCTA 
AAAAATAAAG ATGGTTTAGT CATCTCATGT GGCCCAGATA GCTGTTCTGA ATGGAAACCA 
GGATCCCTTC AACGATTTCA AAACAAAATT ACCTCTACTA CAACAGATGG GGAATCTGTT 
ACGTTCCATT TGTTTGACCA TGTAACCGTA AGAATATCCA TACAGGCCTC ACGTTGCCAT 
TCTGATACAA TCAGACTTGA AATAATTAGT AACAAACCAT ACAAGATACC AAATACAGAA 
CTTATTCATC AGAGTTCCCC CTTGCTGAAG AGTGAGTTAG TGAAAGAAGT AACTAAATCT 
GTGGAAGAAG CTCAGCTTGC CCAAGAAGTC AAAGTAAACA TCATTCAGGA GGAATATCAA 
GAATATCGCC AAACAAAGGG AAGGAGCCTA TACACACTTC TAGAGGAGAT ACGGGACCTA 
GCTCTCCTGG ATGTTTCAAA CAATTATGGA ATATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

DIS3L ( XM_005254147.3 ) cDNA ORF clone, Homo sapiens(human) -> XP_005254204.1 Homo sapiens DIS3 like exosome 3'-5' exoribonuclease (DIS3L), transcript variant X2, mRNA.

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CloneID	OHu09544
Clone ID Related Accession (Same CDS sequence)	NM_001323945.2 , XM_005254147.3 , XM_005254145.2 , NM_001323936.2 , NM_133375.5 , NM_133375.4 , NM_001323945.1 , NM_001323936.1 , NM_133375.3
Accession Version	XM_005254147.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2916bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2015-03-11
Organism	Homo sapiens(Human)
Product	DIS3-like exonuclease 1 isoform X1
Comment

ATGCAGACAG CTTGTCAAGC TGTGCAGCAT CAAAGAGGCA GGAGACAGTA TAACAAACTG 
CGAAACCTGC TGAAGGATGC GCGTCATGAT TGCATTCTCT TTGCTAATGA ATTCCAGCAA 
TGCTGCTATC TGCCACGGGA AAGAGGAGAG TCCATGGAGA AGTGGCAGAC CAGGAGCATA 
TACAACGCAG CTGTTTGGTA CTATCATCAC TGCCAGGACA GGATGCCAAT TGTTATGGTG 
ACAGAAGATG AAGAGGCAAT TCAGCAGTAT GGAAGTGAAA CAGAAGGAGT ATTCGTGATT 
ACTTTCAAGA ATTACCTGGA CAATTTCTGG CCTGATTTAA AAGCTGCCCA CGAGCTTTGT 
GATTCTATCC TTCAGTCTCG ACGGGAGAGA GAGAATGAGA GTCAGGAGAG CCATGGGAAG 
GAGTACCCAG AACATCTTCC CCTGGAAGTG TTAGAAGCTG GGATTAAATC TGGACGCTAT 
ATCCAGGGAA TTCTGAATGT CAACAAACAC AGAGCCCAAA TAGAAGCTTT TGTTCGACTT 
CAAGGAGCCA GCAGTAAAGA TTCAGATTTA GTCAGTGACA TCCTAATCCA CGGGATGAAG 
GCTCGAAACC GCTCAATTCA TGGAGATGTG GTAGTTGTGG AGCTGCTTCC TAAAAATGAA 
TGGAAAGGAA GAACCGTAGC CCTGTGTGAG AATGACTGTG ACGACAAGGC TTCGGGCGAG 
TCCCCAAGTG AGCCCATGCC TACAGGTCGA GTGGTGGGCA TACTTCAGAA GAACTGGCGG 
GATTATGTGG TGACATTTCC GTCCAAAGAA GAGGTCCAAT CTCAGGGCAA AAATGCTCAG 
AAAATCCTGG TTACACCTTG GGATTACAGA ATTCCCAAAA TTCGAATTAG CACTCAGCAA 
GCAGAAACCC TCCAGGACTT CAGGGTGGTC GTGCGCATCG ATTCCTGGGA GTCAACATCT 
GTGTATCCAA ATGGACATTT TGTGCGTGTT TTAGGAAGAA TCGGAGATCT GGAAGGGGAA 
ATTGCAACCA TCCTGGTGGA AAACAGTATT TCAGTTATTC CTTTCTCAGA AGCTCAGATG 
TGTGAGATGC CAGTAAACAC ACCAGAAAGT CCCTGGAAGG TGAGTCCTGA AGAGGAACAA 
AAACGTAAAG ACTTGAGGAA AAGCCATCTC GTATTCAGCA TTGACCCCAA AGGTTGTGAA 
GATGTGGATG ACACACTCTC AGTCAGAACC TTAAATAATG GCAACCTGGA ACTTGGGGTC 
CACATCGCAG ATGTAACACA CTTTGTGGCA CCAAATTCTT ACATTGATAT TGAAGCTAGA 
ACAAGGGCCA CCACTTATTA TCTAGCAGAT CGTCGCTATG ACATGCTGCC TTCCGTCCTC 
AGTGCAGATT TGTGTTCCCT TCTGGGAGGC GTTGATAGGT ATGCTGTAAG CATCATGTGG 
GAACTGGATA AAGCCTCTTA TGAAATTAAG AAAGTGTGGT ATGGCAGAAC CATTATTCGA 
TCAGCATACA AACTGTTCTA TGAAGCAGCC CAAGAACTAC TGGATGGAAA CTTAAGCGTT 
GTTGATGATA TTCCAGAATT CAAAGACTTG GATGAGAAGA GCAGACAAGC CAAGCTGGAG 
GAGTTGGTGT GGGCAATTGG AAAGCTGACC GACATAGCTC GCCATGTCAG AGCTAAACGA 
GACGGATGTG GTGCCCTGGA ACTGGAAGGG GTAGAGGTTT GCGTACAGCT AGATGACAAA 
AAGAACATTC ACGACCTCAT CCCCAAGCAG CCCCTGGAAG TCCACGAGAC AGTGGCTGAA 
TGCATGATCC TGGCCAACCA CTGGGTCGCC AAAAAGATCT GGGAGAGCTT CCCTCATCAG 
GCCTTGCTGC GCCAGCACCC TCCTCCACAC CAGGAGTTCT TTTCAGAACT CCGGGAATGT 
GCTAAAGCCA AAGGCTTCTT CATAGATACA CGGTCCAATA AAACACTGGC TGATTCTCTG 
GATAATGCGA ACGACCCCCA CGATCCCATT GTGAACAGGC TACTGCGCTC CATGGCCACG 
CAGGCCATGT CGAATGCTCT GTACTTCTCC ACCGGATCCT GTGCGGAGGA GGAGTTCCAT 
CATTACGGTC TTGCATTAGA TAAATATACC CACTTTACTT CTCCAATAAG AAGATATTCA 
GATATTGTAG TACACCGCTT GTTAATGGCA GCCATTTCAA AAGATAAGAA AATGGAAATT 
AAGGGAAATC TGTTCAGCAA CAAAGATCTT GAGGAATTAT GCAGACATAT CAACAACAGA 
AACCAAGCAG CACAGCATTC TCAGAAGCAG TCTACTGAGC TCTTCCAGTG CATGTACTTC 
AAAGACAAAG ACCCTGCCAC CGAGGAGCGT TGCATATCTG ACGGAGTTAT TTATTCAATT 
AGAACAAATG GTGTGCTTCT ATTTATACCA AGGTTTGGGA TTAAAGGTGC TGCTTATCTA 
AAAAATAAAG ATGGTTTAGT CATCTCATGT GGCCCAGATA GCTGTTCTGA ATGGAAACCA 
GGATCCCTTC AACGATTTCA AAACAAAATT ACCTCTACTA CAACAGATGG GGAATCTGTT 
ACGTTCCATT TGTTTGACCA TGTAACCGTA AGAATATCCA TACAGGCCTC ACGTTGCCAT 
TCTGATACAA TCAGACTTGA AATAATTAGT AACAAACCAT ACAAGATACC AAATACAGAA 
CTTATTCATC AGAGTTCCCC CTTGCTGAAG AGTGAGTTAG TGAAAGAAGT AACTAAATCT 
GTGGAAGAAG CTCAGCTTGC CCAAGAAGTC AAAGTAAACA TCATTCAGGA GGAATATCAA 
GAATATCGCC AAACAAAGGG AAGGAGCCTA TACACACTTC TAGAGGAGAT ACGGGACCTA 
GCTCTCCTGG ATGTTTCAAA CAATTATGGA ATATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq

XP_005254204.1

Translation

MQTACQAVQHQRGRRQYNKLRNLLKDARHDCILFANEFQQCCYLPRERGESMEKWQTRSIYNAAVWYYHHCQDRMPIVMVTEDEEAIQQYGSETEGVFVITFKNYLDNFWPDLKAAHELCDSILQSRRERENESQESHGKEYPEHLPLEVLEAGIKSGRYIQGILNVNKHRAQIEAFVRLQGASSKDSDLVSDILIHGMKARNRSIHGDVVVVELLPKNEWKGRTVALCENDCDDKASGESPSEPMPTGRVVGILQKNWRDYVVTFPSKEEVQSQGKNAQKILVTPWDYRIPKIRISTQQAETLQDFRVVVRIDSWESTSVYPNGHFVRVLGRIGDLEGEIATILVENSISVIPFSEAQMCEMPVNTPESPWKVSPEEEQKRKDLRKSHLVFSIDPKGCEDVDDTLSVRTLNNGNLELGVHIADVTHFVAPNSYIDIEARTRATTYYLADRRYDMLPSVLSADLCSLLGGVDRYAVSIMWELDKASYEIKKVWYGRTIIRSAYKLFYEAAQELLDGNLSVVDDIPEFKDLDEKSRQAKLEELVWAIGKLTDIARHVRAKRDGCGALELEGVEVCVQLDDKKNIHDLIPKQPLEVHETVAECMILANHWVAKKIWESFPHQALLRQHPPPHQEFFSELRECAKAKGFFIDTRSNKTLADSLDNANDPHDPIVNRLLRSMATQAMSNALYFSTGSCAEEEFHHYGLALDKYTHFTSPIRRYSDIVVHRLLMAAISKDKKMEIKGNLFSNKDLEELCRHINNRNQAAQHSQKQSTELFQCMYFKDKDPATEERCISDGVIYSIRTNGVLLFIPRFGIKGAAYLKNKDGLVISCGPDSCSEWKPGSLQRFQNKITSTTTDGESVTFHLFDHVTVRISIQASRCHSDTIRLEIISNKPYKIPNTELIHQSSPLLKSELVKEVTKSVEEAQLAQEVKVNIIQEEYQEYRQTKGRSLYTLLEEIRDLALLDVSNNYGI

Target ORF information:

RefSeq Version	XM_005254147.3
Organism	Homo sapiens(Human)
Definition	Homo sapiens DIS3 like exosome 3'-5' exoribonuclease (DIS3L), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_005254147.3

ORF Insert Sequence:

ATGCAGACAG CTTGTCAAGC TGTGCAGCAT CAAAGAGGCA GGAGACAGTA TAACAAACTG 
CGAAACCTGC TGAAGGATGC GCGTCATGAT TGCATTCTCT TTGCTAATGA ATTCCAGCAA 
TGCTGCTATC TGCCACGGGA AAGAGGAGAG TCCATGGAGA AGTGGCAGAC CAGGAGCATA 
TACAACGCAG CTGTTTGGTA CTATCATCAC TGCCAGGACA GGATGCCAAT TGTTATGGTG 
ACAGAAGATG AAGAGGCAAT TCAGCAGTAT GGAAGTGAAA CAGAAGGAGT ATTCGTGATT 
ACTTTCAAGA ATTACCTGGA CAATTTCTGG CCTGATTTAA AAGCTGCCCA CGAGCTTTGT 
GATTCTATCC TTCAGTCTCG ACGGGAGAGA GAGAATGAGA GTCAGGAGAG CCATGGGAAG 
GAGTACCCAG AACATCTTCC CCTGGAAGTG TTAGAAGCTG GGATTAAATC TGGACGCTAT 
ATCCAGGGAA TTCTGAATGT CAACAAACAC AGAGCCCAAA TAGAAGCTTT TGTTCGACTT 
CAAGGAGCCA GCAGTAAAGA TTCAGATTTA GTCAGTGACA TCCTAATCCA CGGGATGAAG 
GCTCGAAACC GCTCAATTCA TGGAGATGTG GTAGTTGTGG AGCTGCTTCC TAAAAATGAA 
TGGAAAGGAA GAACCGTAGC CCTGTGTGAG AATGACTGTG ACGACAAGGC TTCGGGCGAG 
TCCCCAAGTG AGCCCATGCC TACAGGTCGA GTGGTGGGCA TACTTCAGAA GAACTGGCGG 
GATTATGTGG TGACATTTCC GTCCAAAGAA GAGGTCCAAT CTCAGGGCAA AAATGCTCAG 
AAAATCCTGG TTACACCTTG GGATTACAGA ATTCCCAAAA TTCGAATTAG CACTCAGCAA 
GCAGAAACCC TCCAGGACTT CAGGGTGGTC GTGCGCATCG ATTCCTGGGA GTCAACATCT 
GTGTATCCAA ATGGACATTT TGTGCGTGTT TTAGGAAGAA TCGGAGATCT GGAAGGGGAA 
ATTGCAACCA TCCTGGTGGA AAACAGTATT TCAGTTATTC CTTTCTCAGA AGCTCAGATG 
TGTGAGATGC CAGTAAACAC ACCAGAAAGT CCCTGGAAGG TGAGTCCTGA AGAGGAACAA 
AAACGTAAAG ACTTGAGGAA AAGCCATCTC GTATTCAGCA TTGACCCCAA AGGTTGTGAA 
GATGTGGATG ACACACTCTC AGTCAGAACC TTAAATAATG GCAACCTGGA ACTTGGGGTC 
CACATCGCAG ATGTAACACA CTTTGTGGCA CCAAATTCTT ACATTGATAT TGAAGCTAGA 
ACAAGGGCCA CCACTTATTA TCTAGCAGAT CGTCGCTATG ACATGCTGCC TTCCGTCCTC 
AGTGCAGATT TGTGTTCCCT TCTGGGAGGC GTTGATAGGT ATGCTGTAAG CATCATGTGG 
GAACTGGATA AAGCCTCTTA TGAAATTAAG AAAGTGTGGT ATGGCAGAAC CATTATTCGA 
TCAGCATACA AACTGTTCTA TGAAGCAGCC CAAGAACTAC TGGATGGAAA CTTAAGCGTT 
GTTGATGATA TTCCAGAATT CAAAGACTTG GATGAGAAGA GCAGACAAGC CAAGCTGGAG 
GAGTTGGTGT GGGCAATTGG AAAGCTGACC GACATAGCTC GCCATGTCAG AGCTAAACGA 
GACGGATGTG GTGCCCTGGA ACTGGAAGGG GTAGAGGTTT GCGTACAGCT AGATGACAAA 
AAGAACATTC ACGACCTCAT CCCCAAGCAG CCCCTGGAAG TCCACGAGAC AGTGGCTGAA 
TGCATGATCC TGGCCAACCA CTGGGTCGCC AAAAAGATCT GGGAGAGCTT CCCTCATCAG 
GCCTTGCTGC GCCAGCACCC TCCTCCACAC CAGGAGTTCT TTTCAGAACT CCGGGAATGT 
GCTAAAGCCA AAGGCTTCTT CATAGATACA CGGTCCAATA AAACACTGGC TGATTCTCTG 
GATAATGCGA ACGACCCCCA CGATCCCATT GTGAACAGGC TACTGCGCTC CATGGCCACG 
CAGGCCATGT CGAATGCTCT GTACTTCTCC ACCGGATCCT GTGCGGAGGA GGAGTTCCAT 
CATTACGGTC TTGCATTAGA TAAATATACC CACTTTACTT CTCCAATAAG AAGATATTCA 
GATATTGTAG TACACCGCTT GTTAATGGCA GCCATTTCAA AAGATAAGAA AATGGAAATT 
AAGGGAAATC TGTTCAGCAA CAAAGATCTT GAGGAATTAT GCAGACATAT CAACAACAGA 
AACCAAGCAG CACAGCATTC TCAGAAGCAG TCTACTGAGC TCTTCCAGTG CATGTACTTC 
AAAGACAAAG ACCCTGCCAC CGAGGAGCGT TGCATATCTG ACGGAGTTAT TTATTCAATT 
AGAACAAATG GTGTGCTTCT ATTTATACCA AGGTTTGGGA TTAAAGGTGC TGCTTATCTA 
AAAAATAAAG ATGGTTTAGT CATCTCATGT GGCCCAGATA GCTGTTCTGA ATGGAAACCA 
GGATCCCTTC AACGATTTCA AAACAAAATT ACCTCTACTA CAACAGATGG GGAATCTGTT 
ACGTTCCATT TGTTTGACCA TGTAACCGTA AGAATATCCA TACAGGCCTC ACGTTGCCAT 
TCTGATACAA TCAGACTTGA AATAATTAGT AACAAACCAT ACAAGATACC AAATACAGAA 
CTTATTCATC AGAGTTCCCC CTTGCTGAAG AGTGAGTTAG TGAAAGAAGT AACTAAATCT 
GTGGAAGAAG CTCAGCTTGC CCAAGAAGTC AAAGTAAACA TCATTCAGGA GGAATATCAA 
GAATATCGCC AAACAAAGGG AAGGAGCCTA TACACACTTC TAGAGGAGAT ACGGGACCTA 
GCTCTCCTGG ATGTTTCAAA CAATTATGGA ATATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

DIS3L ( XM_005254145.2 ) cDNA ORF clone, Homo sapiens(human) -> XP_005254202.1 Homo sapiens DIS3 like exosome 3'-5' exoribonuclease (DIS3L), transcript variant X1, mRNA.

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CloneID	OHu09544
Clone ID Related Accession (Same CDS sequence)	NM_001323945.2 , XM_005254147.3 , XM_005254145.2 , NM_001323936.2 , NM_133375.5 , NM_133375.4 , NM_001323945.1 , NM_001323936.1 , NM_133375.3
Accession Version	XM_005254145.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2916bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2015-03-11
Organism	Homo sapiens(Human)
Product	DIS3-like exonuclease 1 isoform X1
Comment

ATGCAGACAG CTTGTCAAGC TGTGCAGCAT CAAAGAGGCA GGAGACAGTA TAACAAACTG 
CGAAACCTGC TGAAGGATGC GCGTCATGAT TGCATTCTCT TTGCTAATGA ATTCCAGCAA 
TGCTGCTATC TGCCACGGGA AAGAGGAGAG TCCATGGAGA AGTGGCAGAC CAGGAGCATA 
TACAACGCAG CTGTTTGGTA CTATCATCAC TGCCAGGACA GGATGCCAAT TGTTATGGTG 
ACAGAAGATG AAGAGGCAAT TCAGCAGTAT GGAAGTGAAA CAGAAGGAGT ATTCGTGATT 
ACTTTCAAGA ATTACCTGGA CAATTTCTGG CCTGATTTAA AAGCTGCCCA CGAGCTTTGT 
GATTCTATCC TTCAGTCTCG ACGGGAGAGA GAGAATGAGA GTCAGGAGAG CCATGGGAAG 
GAGTACCCAG AACATCTTCC CCTGGAAGTG TTAGAAGCTG GGATTAAATC TGGACGCTAT 
ATCCAGGGAA TTCTGAATGT CAACAAACAC AGAGCCCAAA TAGAAGCTTT TGTTCGACTT 
CAAGGAGCCA GCAGTAAAGA TTCAGATTTA GTCAGTGACA TCCTAATCCA CGGGATGAAG 
GCTCGAAACC GCTCAATTCA TGGAGATGTG GTAGTTGTGG AGCTGCTTCC TAAAAATGAA 
TGGAAAGGAA GAACCGTAGC CCTGTGTGAG AATGACTGTG ACGACAAGGC TTCGGGCGAG 
TCCCCAAGTG AGCCCATGCC TACAGGTCGA GTGGTGGGCA TACTTCAGAA GAACTGGCGG 
GATTATGTGG TGACATTTCC GTCCAAAGAA GAGGTCCAAT CTCAGGGCAA AAATGCTCAG 
AAAATCCTGG TTACACCTTG GGATTACAGA ATTCCCAAAA TTCGAATTAG CACTCAGCAA 
GCAGAAACCC TCCAGGACTT CAGGGTGGTC GTGCGCATCG ATTCCTGGGA GTCAACATCT 
GTGTATCCAA ATGGACATTT TGTGCGTGTT TTAGGAAGAA TCGGAGATCT GGAAGGGGAA 
ATTGCAACCA TCCTGGTGGA AAACAGTATT TCAGTTATTC CTTTCTCAGA AGCTCAGATG 
TGTGAGATGC CAGTAAACAC ACCAGAAAGT CCCTGGAAGG TGAGTCCTGA AGAGGAACAA 
AAACGTAAAG ACTTGAGGAA AAGCCATCTC GTATTCAGCA TTGACCCCAA AGGTTGTGAA 
GATGTGGATG ACACACTCTC AGTCAGAACC TTAAATAATG GCAACCTGGA ACTTGGGGTC 
CACATCGCAG ATGTAACACA CTTTGTGGCA CCAAATTCTT ACATTGATAT TGAAGCTAGA 
ACAAGGGCCA CCACTTATTA TCTAGCAGAT CGTCGCTATG ACATGCTGCC TTCCGTCCTC 
AGTGCAGATT TGTGTTCCCT TCTGGGAGGC GTTGATAGGT ATGCTGTAAG CATCATGTGG 
GAACTGGATA AAGCCTCTTA TGAAATTAAG AAAGTGTGGT ATGGCAGAAC CATTATTCGA 
TCAGCATACA AACTGTTCTA TGAAGCAGCC CAAGAACTAC TGGATGGAAA CTTAAGCGTT 
GTTGATGATA TTCCAGAATT CAAAGACTTG GATGAGAAGA GCAGACAAGC CAAGCTGGAG 
GAGTTGGTGT GGGCAATTGG AAAGCTGACC GACATAGCTC GCCATGTCAG AGCTAAACGA 
GACGGATGTG GTGCCCTGGA ACTGGAAGGG GTAGAGGTTT GCGTACAGCT AGATGACAAA 
AAGAACATTC ACGACCTCAT CCCCAAGCAG CCCCTGGAAG TCCACGAGAC AGTGGCTGAA 
TGCATGATCC TGGCCAACCA CTGGGTCGCC AAAAAGATCT GGGAGAGCTT CCCTCATCAG 
GCCTTGCTGC GCCAGCACCC TCCTCCACAC CAGGAGTTCT TTTCAGAACT CCGGGAATGT 
GCTAAAGCCA AAGGCTTCTT CATAGATACA CGGTCCAATA AAACACTGGC TGATTCTCTG 
GATAATGCGA ACGACCCCCA CGATCCCATT GTGAACAGGC TACTGCGCTC CATGGCCACG 
CAGGCCATGT CGAATGCTCT GTACTTCTCC ACCGGATCCT GTGCGGAGGA GGAGTTCCAT 
CATTACGGTC TTGCATTAGA TAAATATACC CACTTTACTT CTCCAATAAG AAGATATTCA 
GATATTGTAG TACACCGCTT GTTAATGGCA GCCATTTCAA AAGATAAGAA AATGGAAATT 
AAGGGAAATC TGTTCAGCAA CAAAGATCTT GAGGAATTAT GCAGACATAT CAACAACAGA 
AACCAAGCAG CACAGCATTC TCAGAAGCAG TCTACTGAGC TCTTCCAGTG CATGTACTTC 
AAAGACAAAG ACCCTGCCAC CGAGGAGCGT TGCATATCTG ACGGAGTTAT TTATTCAATT 
AGAACAAATG GTGTGCTTCT ATTTATACCA AGGTTTGGGA TTAAAGGTGC TGCTTATCTA 
AAAAATAAAG ATGGTTTAGT CATCTCATGT GGCCCAGATA GCTGTTCTGA ATGGAAACCA 
GGATCCCTTC AACGATTTCA AAACAAAATT ACCTCTACTA CAACAGATGG GGAATCTGTT 
ACGTTCCATT TGTTTGACCA TGTAACCGTA AGAATATCCA TACAGGCCTC ACGTTGCCAT 
TCTGATACAA TCAGACTTGA AATAATTAGT AACAAACCAT ACAAGATACC AAATACAGAA 
CTTATTCATC AGAGTTCCCC CTTGCTGAAG AGTGAGTTAG TGAAAGAAGT AACTAAATCT 
GTGGAAGAAG CTCAGCTTGC CCAAGAAGTC AAAGTAAACA TCATTCAGGA GGAATATCAA 
GAATATCGCC AAACAAAGGG AAGGAGCCTA TACACACTTC TAGAGGAGAT ACGGGACCTA 
GCTCTCCTGG ATGTTTCAAA CAATTATGGA ATATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq

XP_005254202.1

Translation

MQTACQAVQHQRGRRQYNKLRNLLKDARHDCILFANEFQQCCYLPRERGESMEKWQTRSIYNAAVWYYHHCQDRMPIVMVTEDEEAIQQYGSETEGVFVITFKNYLDNFWPDLKAAHELCDSILQSRRERENESQESHGKEYPEHLPLEVLEAGIKSGRYIQGILNVNKHRAQIEAFVRLQGASSKDSDLVSDILIHGMKARNRSIHGDVVVVELLPKNEWKGRTVALCENDCDDKASGESPSEPMPTGRVVGILQKNWRDYVVTFPSKEEVQSQGKNAQKILVTPWDYRIPKIRISTQQAETLQDFRVVVRIDSWESTSVYPNGHFVRVLGRIGDLEGEIATILVENSISVIPFSEAQMCEMPVNTPESPWKVSPEEEQKRKDLRKSHLVFSIDPKGCEDVDDTLSVRTLNNGNLELGVHIADVTHFVAPNSYIDIEARTRATTYYLADRRYDMLPSVLSADLCSLLGGVDRYAVSIMWELDKASYEIKKVWYGRTIIRSAYKLFYEAAQELLDGNLSVVDDIPEFKDLDEKSRQAKLEELVWAIGKLTDIARHVRAKRDGCGALELEGVEVCVQLDDKKNIHDLIPKQPLEVHETVAECMILANHWVAKKIWESFPHQALLRQHPPPHQEFFSELRECAKAKGFFIDTRSNKTLADSLDNANDPHDPIVNRLLRSMATQAMSNALYFSTGSCAEEEFHHYGLALDKYTHFTSPIRRYSDIVVHRLLMAAISKDKKMEIKGNLFSNKDLEELCRHINNRNQAAQHSQKQSTELFQCMYFKDKDPATEERCISDGVIYSIRTNGVLLFIPRFGIKGAAYLKNKDGLVISCGPDSCSEWKPGSLQRFQNKITSTTTDGESVTFHLFDHVTVRISIQASRCHSDTIRLEIISNKPYKIPNTELIHQSSPLLKSELVKEVTKSVEEAQLAQEVKVNIIQEEYQEYRQTKGRSLYTLLEEIRDLALLDVSNNYGI

Target ORF information:

RefSeq Version	XM_005254145.2
Organism	Homo sapiens(Human)
Definition	Homo sapiens DIS3 like exosome 3'-5' exoribonuclease (DIS3L), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_005254145.2

ORF Insert Sequence:

ATGCAGACAG CTTGTCAAGC TGTGCAGCAT CAAAGAGGCA GGAGACAGTA TAACAAACTG 
CGAAACCTGC TGAAGGATGC GCGTCATGAT TGCATTCTCT TTGCTAATGA ATTCCAGCAA 
TGCTGCTATC TGCCACGGGA AAGAGGAGAG TCCATGGAGA AGTGGCAGAC CAGGAGCATA 
TACAACGCAG CTGTTTGGTA CTATCATCAC TGCCAGGACA GGATGCCAAT TGTTATGGTG 
ACAGAAGATG AAGAGGCAAT TCAGCAGTAT GGAAGTGAAA CAGAAGGAGT ATTCGTGATT 
ACTTTCAAGA ATTACCTGGA CAATTTCTGG CCTGATTTAA AAGCTGCCCA CGAGCTTTGT 
GATTCTATCC TTCAGTCTCG ACGGGAGAGA GAGAATGAGA GTCAGGAGAG CCATGGGAAG 
GAGTACCCAG AACATCTTCC CCTGGAAGTG TTAGAAGCTG GGATTAAATC TGGACGCTAT 
ATCCAGGGAA TTCTGAATGT CAACAAACAC AGAGCCCAAA TAGAAGCTTT TGTTCGACTT 
CAAGGAGCCA GCAGTAAAGA TTCAGATTTA GTCAGTGACA TCCTAATCCA CGGGATGAAG 
GCTCGAAACC GCTCAATTCA TGGAGATGTG GTAGTTGTGG AGCTGCTTCC TAAAAATGAA 
TGGAAAGGAA GAACCGTAGC CCTGTGTGAG AATGACTGTG ACGACAAGGC TTCGGGCGAG 
TCCCCAAGTG AGCCCATGCC TACAGGTCGA GTGGTGGGCA TACTTCAGAA GAACTGGCGG 
GATTATGTGG TGACATTTCC GTCCAAAGAA GAGGTCCAAT CTCAGGGCAA AAATGCTCAG 
AAAATCCTGG TTACACCTTG GGATTACAGA ATTCCCAAAA TTCGAATTAG CACTCAGCAA 
GCAGAAACCC TCCAGGACTT CAGGGTGGTC GTGCGCATCG ATTCCTGGGA GTCAACATCT 
GTGTATCCAA ATGGACATTT TGTGCGTGTT TTAGGAAGAA TCGGAGATCT GGAAGGGGAA 
ATTGCAACCA TCCTGGTGGA AAACAGTATT TCAGTTATTC CTTTCTCAGA AGCTCAGATG 
TGTGAGATGC CAGTAAACAC ACCAGAAAGT CCCTGGAAGG TGAGTCCTGA AGAGGAACAA 
AAACGTAAAG ACTTGAGGAA AAGCCATCTC GTATTCAGCA TTGACCCCAA AGGTTGTGAA 
GATGTGGATG ACACACTCTC AGTCAGAACC TTAAATAATG GCAACCTGGA ACTTGGGGTC 
CACATCGCAG ATGTAACACA CTTTGTGGCA CCAAATTCTT ACATTGATAT TGAAGCTAGA 
ACAAGGGCCA CCACTTATTA TCTAGCAGAT CGTCGCTATG ACATGCTGCC TTCCGTCCTC 
AGTGCAGATT TGTGTTCCCT TCTGGGAGGC GTTGATAGGT ATGCTGTAAG CATCATGTGG 
GAACTGGATA AAGCCTCTTA TGAAATTAAG AAAGTGTGGT ATGGCAGAAC CATTATTCGA 
TCAGCATACA AACTGTTCTA TGAAGCAGCC CAAGAACTAC TGGATGGAAA CTTAAGCGTT 
GTTGATGATA TTCCAGAATT CAAAGACTTG GATGAGAAGA GCAGACAAGC CAAGCTGGAG 
GAGTTGGTGT GGGCAATTGG AAAGCTGACC GACATAGCTC GCCATGTCAG AGCTAAACGA 
GACGGATGTG GTGCCCTGGA ACTGGAAGGG GTAGAGGTTT GCGTACAGCT AGATGACAAA 
AAGAACATTC ACGACCTCAT CCCCAAGCAG CCCCTGGAAG TCCACGAGAC AGTGGCTGAA 
TGCATGATCC TGGCCAACCA CTGGGTCGCC AAAAAGATCT GGGAGAGCTT CCCTCATCAG 
GCCTTGCTGC GCCAGCACCC TCCTCCACAC CAGGAGTTCT TTTCAGAACT CCGGGAATGT 
GCTAAAGCCA AAGGCTTCTT CATAGATACA CGGTCCAATA AAACACTGGC TGATTCTCTG 
GATAATGCGA ACGACCCCCA CGATCCCATT GTGAACAGGC TACTGCGCTC CATGGCCACG 
CAGGCCATGT CGAATGCTCT GTACTTCTCC ACCGGATCCT GTGCGGAGGA GGAGTTCCAT 
CATTACGGTC TTGCATTAGA TAAATATACC CACTTTACTT CTCCAATAAG AAGATATTCA 
GATATTGTAG TACACCGCTT GTTAATGGCA GCCATTTCAA AAGATAAGAA AATGGAAATT 
AAGGGAAATC TGTTCAGCAA CAAAGATCTT GAGGAATTAT GCAGACATAT CAACAACAGA 
AACCAAGCAG CACAGCATTC TCAGAAGCAG TCTACTGAGC TCTTCCAGTG CATGTACTTC 
AAAGACAAAG ACCCTGCCAC CGAGGAGCGT TGCATATCTG ACGGAGTTAT TTATTCAATT 
AGAACAAATG GTGTGCTTCT ATTTATACCA AGGTTTGGGA TTAAAGGTGC TGCTTATCTA 
AAAAATAAAG ATGGTTTAGT CATCTCATGT GGCCCAGATA GCTGTTCTGA ATGGAAACCA 
GGATCCCTTC AACGATTTCA AAACAAAATT ACCTCTACTA CAACAGATGG GGAATCTGTT 
ACGTTCCATT TGTTTGACCA TGTAACCGTA AGAATATCCA TACAGGCCTC ACGTTGCCAT 
TCTGATACAA TCAGACTTGA AATAATTAGT AACAAACCAT ACAAGATACC AAATACAGAA 
CTTATTCATC AGAGTTCCCC CTTGCTGAAG AGTGAGTTAG TGAAAGAAGT AACTAAATCT 
GTGGAAGAAG CTCAGCTTGC CCAAGAAGTC AAAGTAAACA TCATTCAGGA GGAATATCAA 
GAATATCGCC AAACAAAGGG AAGGAGCCTA TACACACTTC TAGAGGAGAT ACGGGACCTA 
GCTCTCCTGG ATGTTTCAAA CAATTATGGA ATATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

DIS3L ( NM_001323941.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_001310870.1 Homo sapiens DIS3 like exosome 3'-5' exoribonuclease (DIS3L), transcript variant 8, mRNA.

Price & Availability↑

CloneID	OHu82920
Clone ID Related Accession (Same CDS sequence)	NM_001323941.2 , NM_001323938.2 , NM_001323946.1 , NM_001323939.1 , NM_001323939.2 , NM_001323938.1 , NM_001323946.2 , NM_001323941.1
Accession Version	NM_001323941.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2763bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-09-27
Organism	Homo sapiens(human)
Product	DIS3-like exonuclease 1 isoform 3
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AC055855.9. On May 31, 2019 this sequence version replaced NM_001323941.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. ##Evidence-Data-START## Transcript exon combination :: SRR1803614.28200.1, SRR1803611.181681.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968968, SAMEA2144120 [ECO:0000348] ##Evidence-Data-END##

ATGGAGAAGT GGCAGACCAG GAGCATATAC AACGCAGCTG TTTGGTACTA TCATCACTGC 
CAGGACAGGA TGCCAATTGT TATGGTGACA GAAGATGAAG AGGCAATTCA GCAGTATGGA 
AGTGAAACAG AAGGAGTATT CGTGATTACT TTCAAGAATT ACCTGGACAA TTTCTGGCCT 
GATTTAAAAG CTGCCCACGA GCTTTGTGAT TCTATCCTTC AGTCTCGACG GGAGAGAGAG 
AATGAGAGTC AGGAGAGCCA TGGGAAGGAG TACCCAGAAC ATCTTCCCCT GGAAGTGTTA 
GAAGCTGGGA TTAAATCTGG ACGCTATATC CAGGGAATTC TGAATGTCAA CAAACACAGA 
GCCCAAATAG AAGCTTTTGT TCGACTTCAA GGAGCCAGCA GTAAAGATTC AGATTTAGTC 
AGTGACATCC TAATCCACGG GATGAAGGCT CGAAACCGCT CAATTCATGG AGATGTGGTA 
GTTGTGGAGC TGCTTCCTAA AAATGAATGG AAAGGAAGAA CCGTAGCCCT GTGTGAGAAT 
GACTGTGACG ACAAGGCTTC GGGCGAGTCC CCAAGTGAGC CCATGCCTAC AGGTCGAGTG 
GTGGGCATAC TTCAGAAGAA CTGGCGGGAT TATGTGGTGA CATTTCCGTC CAAAGAAGAG 
GTCCAATCTC AGGGCAAAAA TGCTCAGAAA ATCCTGGTTA CACCTTGGGA TTACAGAATT 
CCCAAAATTC GAATTAGCAC TCAGCAAGCA GAAACCCTCC AGGACTTCAG GGTGGTCGTG 
CGCATCGATT CCTGGGAGTC AACATCTGTG TATCCAAATG GACATTTTGT GCGTGTTTTA 
GGAAGAATCG GAGATCTGGA AGGGGAAATT GCAACCATCC TGGTGGAAAA CAGTATTTCA 
GTTATTCCTT TCTCAGAAGC TCAGATGTGT GAGATGCCAG TAAACACACC AGAAAGTCCC 
TGGAAGGTGA GTCCTGAAGA GGAACAAAAA CGTAAAGACT TGAGGAAAAG CCATCTCGTA 
TTCAGCATTG ACCCCAAAGG TTGTGAAGAT GTGGATGACA CACTCTCAGT CAGAACCTTA 
AATAATGGCA ACCTGGAACT TGGGGTCCAC ATCGCAGATG TAACACACTT TGTGGCACCA 
AATTCTTACA TTGATATTGA AGCTAGAACA AGGGCCACCA CTTATTATCT AGCAGATCGT 
CGCTATGACA TGCTGCCTTC CGTCCTCAGT GCAGATTTGT GTTCCCTTCT GGGAGGCGTT 
GATAGGTATG CTGTAAGCAT CATGTGGGAA CTGGATAAAG CCTCTTATGA AATTAAGAAA 
GTGTGGTATG GCAGAACCAT TATTCGATCA GCATACAAAC TGTTCTATGA AGCAGCCCAA 
GAACTACTGG ATGGAAACTT AAGCGTTGTT GATGATATTC CAGAATTCAA AGACTTGGAT 
GAGAAGAGCA GACAAGCCAA GCTGGAGGAG TTGGTGTGGG CAATTGGAAA GCTGACCGAC 
ATAGCTCGCC ATGTCAGAGC TAAACGAGAC GGATGTGGTG CCCTGGAACT GGAAGGGGTA 
GAGGTTTGCG TACAGCTAGA TGACAAAAAG AACATTCACG ACCTCATCCC CAAGCAGCCC 
CTGGAAGTCC ACGAGACAGT GGCTGAATGC ATGATCCTGG CCAACCACTG GGTCGCCAAA 
AAGATCTGGG AGAGCTTCCC TCATCAGGCC TTGCTGCGCC AGCACCCTCC TCCACACCAG 
GAGTTCTTTT CAGAACTCCG GGAATGTGCT AAAGCCAAAG GCTTCTTCAT AGATACACGG 
TCCAATAAAA CACTGGCTGA TTCTCTGGAT AATGCGAACG ACCCCCACGA TCCCATTGTG 
AACAGGCTAC TGCGCTCCAT GGCCACGCAG GCCATGTCGA ATGCTCTGTA CTTCTCCACC 
GGATCCTGTG CGGAGGAGGA GTTCCATCAT TACGGTCTTG CATTAGATAA ATATACCCAC 
TTTACTTCTC CAATAAGAAG ATATTCAGAT ATTGTAGTAC ACCGCTTGTT AATGGCAGCC 
ATTTCAAAAG ATAAGAAAAT GGAAATTAAG GGAAATCTGT TCAGCAACAA AGATCTTGAG 
GAATTATGCA GACATATCAA CAACAGAAAC CAAGCAGCAC AGCATTCTCA GAAGCAGTCT 
ACTGAGCTCT TCCAGTGCAT GTACTTCAAA GACAAAGACC CTGCCACCGA GGAGCGTTGC 
ATATCTGACG GAGTTATTTA TTCAATTAGA ACAAATGGTG TGCTTCTATT TATACCAAGG 
TTTGGGATTA AAGGTGCTGC TTATCTAAAA AATAAAGATG GTTTAGTCAT CTCATGTGGC 
CCAGATAGCT GTTCTGAATG GAAACCAGGA TCCCTTCAAC GATTTCAAAA CAAAATTACC 
TCTACTACAA CAGATGGGGA ATCTGTTACG TTCCATTTGT TTGACCATGT AACCGTAAGA 
ATATCCATAC AGGCCTCACG TTGCCATTCT GATACAATCA GACTTGAAAT AATTAGTAAC 
AAACCATACA AGATACCAAA TACAGAACTT ATTCATCAGA GTTCCCCCTT GCTGAAGAGT 
GAGTTAGTGA AAGAAGTAAC TAAATCTGTG GAAGAAGCTC AGCTTGCCCA AGAAGTCAAA 
GTAAACATCA TTCAGGAGGA ATATCAAGAA TATCGCCAAA CAAAGGGAAG GAGCCTATAC 
ACACTTCTAG AGGAGATACG GGACCTAGCT CTCCTGGATG TTTCAAACAA TTATGGAATA 
TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001310870.1
CDS	825..3587
Translation	MEKWQTRSIYNAAVWYYHHCQDRMPIVMVTEDEEAIQQYGSETEGVFVITFKNYLDNFWPDLKAAHELCDSILQSRRERENESQESHGKEYPEHLPLEVLEAGIKSGRYIQGILNVNKHRAQIEAFVRLQGASSKDSDLVSDILIHGMKARNRSIHGDVVVVELLPKNEWKGRTVALCENDCDDKASGESPSEPMPTGRVVGILQKNWRDYVVTFPSKEEVQSQGKNAQKILVTPWDYRIPKIRISTQQAETLQDFRVVVRIDSWESTSVYPNGHFVRVLGRIGDLEGEIATILVENSISVIPFSEAQMCEMPVNTPESPWKVSPEEEQKRKDLRKSHLVFSIDPKGCEDVDDTLSVRTLNNGNLELGVHIADVTHFVAPNSYIDIEARTRATTYYLADRRYDMLPSVLSADLCSLLGGVDRYAVSIMWELDKASYEIKKVWYGRTIIRSAYKLFYEAAQELLDGNLSVVDDIPEFKDLDEKSRQAKLEELVWAIGKLTDIARHVRAKRDGCGALELEGVEVCVQLDDKKNIHDLIPKQPLEVHETVAECMILANHWVAKKIWESFPHQALLRQHPPPHQEFFSELRECAKAKGFFIDTRSNKTLADSLDNANDPHDPIVNRLLRSMATQAMSNALYFSTGSCAEEEFHHYGLALDKYTHFTSPIRRYSDIVVHRLLMAAISKDKKMEIKGNLFSNKDLEELCRHINNRNQAAQHSQKQSTELFQCMYFKDKDPATEERCISDGVIYSIRTNGVLLFIPRFGIKGAAYLKNKDGLVISCGPDSCSEWKPGSLQRFQNKITSTTTDGESVTFHLFDHVTVRISIQASRCHSDTIRLEIISNKPYKIPNTELIHQSSPLLKSELVKEVTKSVEEAQLAQEVKVNIIQEEYQEYRQTKGRSLYTLLEEIRDLALLDVSNNYGI

Target ORF information:

RefSeq Version	NM_001323941.2
Organism	Homo sapiens(human)
Definition	Homo sapiens DIS3 like exosome 3'-5' exoribonuclease (DIS3L), transcript variant 8, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001323941.2

ORF Insert Sequence:

ATGGAGAAGT GGCAGACCAG GAGCATATAC AACGCAGCTG TTTGGTACTA TCATCACTGC 
CAGGACAGGA TGCCAATTGT TATGGTGACA GAAGATGAAG AGGCAATTCA GCAGTATGGA 
AGTGAAACAG AAGGAGTATT CGTGATTACT TTCAAGAATT ACCTGGACAA TTTCTGGCCT 
GATTTAAAAG CTGCCCACGA GCTTTGTGAT TCTATCCTTC AGTCTCGACG GGAGAGAGAG 
AATGAGAGTC AGGAGAGCCA TGGGAAGGAG TACCCAGAAC ATCTTCCCCT GGAAGTGTTA 
GAAGCTGGGA TTAAATCTGG ACGCTATATC CAGGGAATTC TGAATGTCAA CAAACACAGA 
GCCCAAATAG AAGCTTTTGT TCGACTTCAA GGAGCCAGCA GTAAAGATTC AGATTTAGTC 
AGTGACATCC TAATCCACGG GATGAAGGCT CGAAACCGCT CAATTCATGG AGATGTGGTA 
GTTGTGGAGC TGCTTCCTAA AAATGAATGG AAAGGAAGAA CCGTAGCCCT GTGTGAGAAT 
GACTGTGACG ACAAGGCTTC GGGCGAGTCC CCAAGTGAGC CCATGCCTAC AGGTCGAGTG 
GTGGGCATAC TTCAGAAGAA CTGGCGGGAT TATGTGGTGA CATTTCCGTC CAAAGAAGAG 
GTCCAATCTC AGGGCAAAAA TGCTCAGAAA ATCCTGGTTA CACCTTGGGA TTACAGAATT 
CCCAAAATTC GAATTAGCAC TCAGCAAGCA GAAACCCTCC AGGACTTCAG GGTGGTCGTG 
CGCATCGATT CCTGGGAGTC AACATCTGTG TATCCAAATG GACATTTTGT GCGTGTTTTA 
GGAAGAATCG GAGATCTGGA AGGGGAAATT GCAACCATCC TGGTGGAAAA CAGTATTTCA 
GTTATTCCTT TCTCAGAAGC TCAGATGTGT GAGATGCCAG TAAACACACC AGAAAGTCCC 
TGGAAGGTGA GTCCTGAAGA GGAACAAAAA CGTAAAGACT TGAGGAAAAG CCATCTCGTA 
TTCAGCATTG ACCCCAAAGG TTGTGAAGAT GTGGATGACA CACTCTCAGT CAGAACCTTA 
AATAATGGCA ACCTGGAACT TGGGGTCCAC ATCGCAGATG TAACACACTT TGTGGCACCA 
AATTCTTACA TTGATATTGA AGCTAGAACA AGGGCCACCA CTTATTATCT AGCAGATCGT 
CGCTATGACA TGCTGCCTTC CGTCCTCAGT GCAGATTTGT GTTCCCTTCT GGGAGGCGTT 
GATAGGTATG CTGTAAGCAT CATGTGGGAA CTGGATAAAG CCTCTTATGA AATTAAGAAA 
GTGTGGTATG GCAGAACCAT TATTCGATCA GCATACAAAC TGTTCTATGA AGCAGCCCAA 
GAACTACTGG ATGGAAACTT AAGCGTTGTT GATGATATTC CAGAATTCAA AGACTTGGAT 
GAGAAGAGCA GACAAGCCAA GCTGGAGGAG TTGGTGTGGG CAATTGGAAA GCTGACCGAC 
ATAGCTCGCC ATGTCAGAGC TAAACGAGAC GGATGTGGTG CCCTGGAACT GGAAGGGGTA 
GAGGTTTGCG TACAGCTAGA TGACAAAAAG AACATTCACG ACCTCATCCC CAAGCAGCCC 
CTGGAAGTCC ACGAGACAGT GGCTGAATGC ATGATCCTGG CCAACCACTG GGTCGCCAAA 
AAGATCTGGG AGAGCTTCCC TCATCAGGCC TTGCTGCGCC AGCACCCTCC TCCACACCAG 
GAGTTCTTTT CAGAACTCCG GGAATGTGCT AAAGCCAAAG GCTTCTTCAT AGATACACGG 
TCCAATAAAA CACTGGCTGA TTCTCTGGAT AATGCGAACG ACCCCCACGA TCCCATTGTG 
AACAGGCTAC TGCGCTCCAT GGCCACGCAG GCCATGTCGA ATGCTCTGTA CTTCTCCACC 
GGATCCTGTG CGGAGGAGGA GTTCCATCAT TACGGTCTTG CATTAGATAA ATATACCCAC 
TTTACTTCTC CAATAAGAAG ATATTCAGAT ATTGTAGTAC ACCGCTTGTT AATGGCAGCC 
ATTTCAAAAG ATAAGAAAAT GGAAATTAAG GGAAATCTGT TCAGCAACAA AGATCTTGAG 
GAATTATGCA GACATATCAA CAACAGAAAC CAAGCAGCAC AGCATTCTCA GAAGCAGTCT 
ACTGAGCTCT TCCAGTGCAT GTACTTCAAA GACAAAGACC CTGCCACCGA GGAGCGTTGC 
ATATCTGACG GAGTTATTTA TTCAATTAGA ACAAATGGTG TGCTTCTATT TATACCAAGG 
TTTGGGATTA AAGGTGCTGC TTATCTAAAA AATAAAGATG GTTTAGTCAT CTCATGTGGC 
CCAGATAGCT GTTCTGAATG GAAACCAGGA TCCCTTCAAC GATTTCAAAA CAAAATTACC 
TCTACTACAA CAGATGGGGA ATCTGTTACG TTCCATTTGT TTGACCATGT AACCGTAAGA 
ATATCCATAC AGGCCTCACG TTGCCATTCT GATACAATCA GACTTGAAAT AATTAGTAAC 
AAACCATACA AGATACCAAA TACAGAACTT ATTCATCAGA GTTCCCCCTT GCTGAAGAGT 
GAGTTAGTGA AAGAAGTAAC TAAATCTGTG GAAGAAGCTC AGCTTGCCCA AGAAGTCAAA 
GTAAACATCA TTCAGGAGGA ATATCAAGAA TATCGCCAAA CAAAGGGAAG GAGCCTATAC 
ACACTTCTAG AGGAGATACG GGACCTAGCT CTCCTGGATG TTTCAAACAA TTATGGAATA 
TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

DIS3L ( NM_001323938.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_001310867.1 Homo sapiens DIS3 like exosome 3'-5' exoribonuclease (DIS3L), transcript variant 5, mRNA.

Price & Availability↑

CloneID	OHu82920
Clone ID Related Accession (Same CDS sequence)	NM_001323941.2 , NM_001323938.2 , NM_001323946.1 , NM_001323939.1 , NM_001323939.2 , NM_001323938.1 , NM_001323946.2 , NM_001323941.1
Accession Version	NM_001323938.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2763bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-09-27
Organism	Homo sapiens(human)
Product	DIS3-like exonuclease 1 isoform 3
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AC055855.9. On May 31, 2019 this sequence version replaced NM_001323938.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. ##Evidence-Data-START## Transcript exon combination :: SRR1803612.183177.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1968540 [ECO:0000348] ##Evidence-Data-END##

ATGGAGAAGT GGCAGACCAG GAGCATATAC AACGCAGCTG TTTGGTACTA TCATCACTGC 
CAGGACAGGA TGCCAATTGT TATGGTGACA GAAGATGAAG AGGCAATTCA GCAGTATGGA 
AGTGAAACAG AAGGAGTATT CGTGATTACT TTCAAGAATT ACCTGGACAA TTTCTGGCCT 
GATTTAAAAG CTGCCCACGA GCTTTGTGAT TCTATCCTTC AGTCTCGACG GGAGAGAGAG 
AATGAGAGTC AGGAGAGCCA TGGGAAGGAG TACCCAGAAC ATCTTCCCCT GGAAGTGTTA 
GAAGCTGGGA TTAAATCTGG ACGCTATATC CAGGGAATTC TGAATGTCAA CAAACACAGA 
GCCCAAATAG AAGCTTTTGT TCGACTTCAA GGAGCCAGCA GTAAAGATTC AGATTTAGTC 
AGTGACATCC TAATCCACGG GATGAAGGCT CGAAACCGCT CAATTCATGG AGATGTGGTA 
GTTGTGGAGC TGCTTCCTAA AAATGAATGG AAAGGAAGAA CCGTAGCCCT GTGTGAGAAT 
GACTGTGACG ACAAGGCTTC GGGCGAGTCC CCAAGTGAGC CCATGCCTAC AGGTCGAGTG 
GTGGGCATAC TTCAGAAGAA CTGGCGGGAT TATGTGGTGA CATTTCCGTC CAAAGAAGAG 
GTCCAATCTC AGGGCAAAAA TGCTCAGAAA ATCCTGGTTA CACCTTGGGA TTACAGAATT 
CCCAAAATTC GAATTAGCAC TCAGCAAGCA GAAACCCTCC AGGACTTCAG GGTGGTCGTG 
CGCATCGATT CCTGGGAGTC AACATCTGTG TATCCAAATG GACATTTTGT GCGTGTTTTA 
GGAAGAATCG GAGATCTGGA AGGGGAAATT GCAACCATCC TGGTGGAAAA CAGTATTTCA 
GTTATTCCTT TCTCAGAAGC TCAGATGTGT GAGATGCCAG TAAACACACC AGAAAGTCCC 
TGGAAGGTGA GTCCTGAAGA GGAACAAAAA CGTAAAGACT TGAGGAAAAG CCATCTCGTA 
TTCAGCATTG ACCCCAAAGG TTGTGAAGAT GTGGATGACA CACTCTCAGT CAGAACCTTA 
AATAATGGCA ACCTGGAACT TGGGGTCCAC ATCGCAGATG TAACACACTT TGTGGCACCA 
AATTCTTACA TTGATATTGA AGCTAGAACA AGGGCCACCA CTTATTATCT AGCAGATCGT 
CGCTATGACA TGCTGCCTTC CGTCCTCAGT GCAGATTTGT GTTCCCTTCT GGGAGGCGTT 
GATAGGTATG CTGTAAGCAT CATGTGGGAA CTGGATAAAG CCTCTTATGA AATTAAGAAA 
GTGTGGTATG GCAGAACCAT TATTCGATCA GCATACAAAC TGTTCTATGA AGCAGCCCAA 
GAACTACTGG ATGGAAACTT AAGCGTTGTT GATGATATTC CAGAATTCAA AGACTTGGAT 
GAGAAGAGCA GACAAGCCAA GCTGGAGGAG TTGGTGTGGG CAATTGGAAA GCTGACCGAC 
ATAGCTCGCC ATGTCAGAGC TAAACGAGAC GGATGTGGTG CCCTGGAACT GGAAGGGGTA 
GAGGTTTGCG TACAGCTAGA TGACAAAAAG AACATTCACG ACCTCATCCC CAAGCAGCCC 
CTGGAAGTCC ACGAGACAGT GGCTGAATGC ATGATCCTGG CCAACCACTG GGTCGCCAAA 
AAGATCTGGG AGAGCTTCCC TCATCAGGCC TTGCTGCGCC AGCACCCTCC TCCACACCAG 
GAGTTCTTTT CAGAACTCCG GGAATGTGCT AAAGCCAAAG GCTTCTTCAT AGATACACGG 
TCCAATAAAA CACTGGCTGA TTCTCTGGAT AATGCGAACG ACCCCCACGA TCCCATTGTG 
AACAGGCTAC TGCGCTCCAT GGCCACGCAG GCCATGTCGA ATGCTCTGTA CTTCTCCACC 
GGATCCTGTG CGGAGGAGGA GTTCCATCAT TACGGTCTTG CATTAGATAA ATATACCCAC 
TTTACTTCTC CAATAAGAAG ATATTCAGAT ATTGTAGTAC ACCGCTTGTT AATGGCAGCC 
ATTTCAAAAG ATAAGAAAAT GGAAATTAAG GGAAATCTGT TCAGCAACAA AGATCTTGAG 
GAATTATGCA GACATATCAA CAACAGAAAC CAAGCAGCAC AGCATTCTCA GAAGCAGTCT 
ACTGAGCTCT TCCAGTGCAT GTACTTCAAA GACAAAGACC CTGCCACCGA GGAGCGTTGC 
ATATCTGACG GAGTTATTTA TTCAATTAGA ACAAATGGTG TGCTTCTATT TATACCAAGG 
TTTGGGATTA AAGGTGCTGC TTATCTAAAA AATAAAGATG GTTTAGTCAT CTCATGTGGC 
CCAGATAGCT GTTCTGAATG GAAACCAGGA TCCCTTCAAC GATTTCAAAA CAAAATTACC 
TCTACTACAA CAGATGGGGA ATCTGTTACG TTCCATTTGT TTGACCATGT AACCGTAAGA 
ATATCCATAC AGGCCTCACG TTGCCATTCT GATACAATCA GACTTGAAAT AATTAGTAAC 
AAACCATACA AGATACCAAA TACAGAACTT ATTCATCAGA GTTCCCCCTT GCTGAAGAGT 
GAGTTAGTGA AAGAAGTAAC TAAATCTGTG GAAGAAGCTC AGCTTGCCCA AGAAGTCAAA 
GTAAACATCA TTCAGGAGGA ATATCAAGAA TATCGCCAAA CAAAGGGAAG GAGCCTATAC 
ACACTTCTAG AGGAGATACG GGACCTAGCT CTCCTGGATG TTTCAAACAA TTATGGAATA 
TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001310867.1
CDS	359..3121
Translation	MEKWQTRSIYNAAVWYYHHCQDRMPIVMVTEDEEAIQQYGSETEGVFVITFKNYLDNFWPDLKAAHELCDSILQSRRERENESQESHGKEYPEHLPLEVLEAGIKSGRYIQGILNVNKHRAQIEAFVRLQGASSKDSDLVSDILIHGMKARNRSIHGDVVVVELLPKNEWKGRTVALCENDCDDKASGESPSEPMPTGRVVGILQKNWRDYVVTFPSKEEVQSQGKNAQKILVTPWDYRIPKIRISTQQAETLQDFRVVVRIDSWESTSVYPNGHFVRVLGRIGDLEGEIATILVENSISVIPFSEAQMCEMPVNTPESPWKVSPEEEQKRKDLRKSHLVFSIDPKGCEDVDDTLSVRTLNNGNLELGVHIADVTHFVAPNSYIDIEARTRATTYYLADRRYDMLPSVLSADLCSLLGGVDRYAVSIMWELDKASYEIKKVWYGRTIIRSAYKLFYEAAQELLDGNLSVVDDIPEFKDLDEKSRQAKLEELVWAIGKLTDIARHVRAKRDGCGALELEGVEVCVQLDDKKNIHDLIPKQPLEVHETVAECMILANHWVAKKIWESFPHQALLRQHPPPHQEFFSELRECAKAKGFFIDTRSNKTLADSLDNANDPHDPIVNRLLRSMATQAMSNALYFSTGSCAEEEFHHYGLALDKYTHFTSPIRRYSDIVVHRLLMAAISKDKKMEIKGNLFSNKDLEELCRHINNRNQAAQHSQKQSTELFQCMYFKDKDPATEERCISDGVIYSIRTNGVLLFIPRFGIKGAAYLKNKDGLVISCGPDSCSEWKPGSLQRFQNKITSTTTDGESVTFHLFDHVTVRISIQASRCHSDTIRLEIISNKPYKIPNTELIHQSSPLLKSELVKEVTKSVEEAQLAQEVKVNIIQEEYQEYRQTKGRSLYTLLEEIRDLALLDVSNNYGI

Target ORF information:

RefSeq Version	NM_001323938.2
Organism	Homo sapiens(human)
Definition	Homo sapiens DIS3 like exosome 3'-5' exoribonuclease (DIS3L), transcript variant 5, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001323938.2

ORF Insert Sequence:

ATGGAGAAGT GGCAGACCAG GAGCATATAC AACGCAGCTG TTTGGTACTA TCATCACTGC 
CAGGACAGGA TGCCAATTGT TATGGTGACA GAAGATGAAG AGGCAATTCA GCAGTATGGA 
AGTGAAACAG AAGGAGTATT CGTGATTACT TTCAAGAATT ACCTGGACAA TTTCTGGCCT 
GATTTAAAAG CTGCCCACGA GCTTTGTGAT TCTATCCTTC AGTCTCGACG GGAGAGAGAG 
AATGAGAGTC AGGAGAGCCA TGGGAAGGAG TACCCAGAAC ATCTTCCCCT GGAAGTGTTA 
GAAGCTGGGA TTAAATCTGG ACGCTATATC CAGGGAATTC TGAATGTCAA CAAACACAGA 
GCCCAAATAG AAGCTTTTGT TCGACTTCAA GGAGCCAGCA GTAAAGATTC AGATTTAGTC 
AGTGACATCC TAATCCACGG GATGAAGGCT CGAAACCGCT CAATTCATGG AGATGTGGTA 
GTTGTGGAGC TGCTTCCTAA AAATGAATGG AAAGGAAGAA CCGTAGCCCT GTGTGAGAAT 
GACTGTGACG ACAAGGCTTC GGGCGAGTCC CCAAGTGAGC CCATGCCTAC AGGTCGAGTG 
GTGGGCATAC TTCAGAAGAA CTGGCGGGAT TATGTGGTGA CATTTCCGTC CAAAGAAGAG 
GTCCAATCTC AGGGCAAAAA TGCTCAGAAA ATCCTGGTTA CACCTTGGGA TTACAGAATT 
CCCAAAATTC GAATTAGCAC TCAGCAAGCA GAAACCCTCC AGGACTTCAG GGTGGTCGTG 
CGCATCGATT CCTGGGAGTC AACATCTGTG TATCCAAATG GACATTTTGT GCGTGTTTTA 
GGAAGAATCG GAGATCTGGA AGGGGAAATT GCAACCATCC TGGTGGAAAA CAGTATTTCA 
GTTATTCCTT TCTCAGAAGC TCAGATGTGT GAGATGCCAG TAAACACACC AGAAAGTCCC 
TGGAAGGTGA GTCCTGAAGA GGAACAAAAA CGTAAAGACT TGAGGAAAAG CCATCTCGTA 
TTCAGCATTG ACCCCAAAGG TTGTGAAGAT GTGGATGACA CACTCTCAGT CAGAACCTTA 
AATAATGGCA ACCTGGAACT TGGGGTCCAC ATCGCAGATG TAACACACTT TGTGGCACCA 
AATTCTTACA TTGATATTGA AGCTAGAACA AGGGCCACCA CTTATTATCT AGCAGATCGT 
CGCTATGACA TGCTGCCTTC CGTCCTCAGT GCAGATTTGT GTTCCCTTCT GGGAGGCGTT 
GATAGGTATG CTGTAAGCAT CATGTGGGAA CTGGATAAAG CCTCTTATGA AATTAAGAAA 
GTGTGGTATG GCAGAACCAT TATTCGATCA GCATACAAAC TGTTCTATGA AGCAGCCCAA 
GAACTACTGG ATGGAAACTT AAGCGTTGTT GATGATATTC CAGAATTCAA AGACTTGGAT 
GAGAAGAGCA GACAAGCCAA GCTGGAGGAG TTGGTGTGGG CAATTGGAAA GCTGACCGAC 
ATAGCTCGCC ATGTCAGAGC TAAACGAGAC GGATGTGGTG CCCTGGAACT GGAAGGGGTA 
GAGGTTTGCG TACAGCTAGA TGACAAAAAG AACATTCACG ACCTCATCCC CAAGCAGCCC 
CTGGAAGTCC ACGAGACAGT GGCTGAATGC ATGATCCTGG CCAACCACTG GGTCGCCAAA 
AAGATCTGGG AGAGCTTCCC TCATCAGGCC TTGCTGCGCC AGCACCCTCC TCCACACCAG 
GAGTTCTTTT CAGAACTCCG GGAATGTGCT AAAGCCAAAG GCTTCTTCAT AGATACACGG 
TCCAATAAAA CACTGGCTGA TTCTCTGGAT AATGCGAACG ACCCCCACGA TCCCATTGTG 
AACAGGCTAC TGCGCTCCAT GGCCACGCAG GCCATGTCGA ATGCTCTGTA CTTCTCCACC 
GGATCCTGTG CGGAGGAGGA GTTCCATCAT TACGGTCTTG CATTAGATAA ATATACCCAC 
TTTACTTCTC CAATAAGAAG ATATTCAGAT ATTGTAGTAC ACCGCTTGTT AATGGCAGCC 
ATTTCAAAAG ATAAGAAAAT GGAAATTAAG GGAAATCTGT TCAGCAACAA AGATCTTGAG 
GAATTATGCA GACATATCAA CAACAGAAAC CAAGCAGCAC AGCATTCTCA GAAGCAGTCT 
ACTGAGCTCT TCCAGTGCAT GTACTTCAAA GACAAAGACC CTGCCACCGA GGAGCGTTGC 
ATATCTGACG GAGTTATTTA TTCAATTAGA ACAAATGGTG TGCTTCTATT TATACCAAGG 
TTTGGGATTA AAGGTGCTGC TTATCTAAAA AATAAAGATG GTTTAGTCAT CTCATGTGGC 
CCAGATAGCT GTTCTGAATG GAAACCAGGA TCCCTTCAAC GATTTCAAAA CAAAATTACC 
TCTACTACAA CAGATGGGGA ATCTGTTACG TTCCATTTGT TTGACCATGT AACCGTAAGA 
ATATCCATAC AGGCCTCACG TTGCCATTCT GATACAATCA GACTTGAAAT AATTAGTAAC 
AAACCATACA AGATACCAAA TACAGAACTT ATTCATCAGA GTTCCCCCTT GCTGAAGAGT 
GAGTTAGTGA AAGAAGTAAC TAAATCTGTG GAAGAAGCTC AGCTTGCCCA AGAAGTCAAA 
GTAAACATCA TTCAGGAGGA ATATCAAGAA TATCGCCAAA CAAAGGGAAG GAGCCTATAC 
ACACTTCTAG AGGAGATACG GGACCTAGCT CTCCTGGATG TTTCAAACAA TTATGGAATA 
TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

DIS3L ( NM_001323946.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001310875.1 Homo sapiens DIS3 like exosome 3'-5' exoribonuclease (DIS3L), transcript variant 12, mRNA.

Price & Availability↑

CloneID	OHu82920
Clone ID Related Accession (Same CDS sequence)	NM_001323941.2 , NM_001323938.2 , NM_001323946.1 , NM_001323939.1 , NM_001323939.2 , NM_001323938.1 , NM_001323946.2 , NM_001323941.1
Accession Version	NM_001323946.1	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2763bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2018-12-04
Organism	Homo sapiens(human)
Product	DIS3-like exonuclease 1 isoform 3
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AC055855.9. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. ##Evidence-Data-START## Transcript exon combination :: SRR1803614.213107.1, SRR1803614.58121.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1968540 [ECO:0000348] ##Evidence-Data-END##

ATGGAGAAGT GGCAGACCAG GAGCATATAC AACGCAGCTG TTTGGTACTA TCATCACTGC 
CAGGACAGGA TGCCAATTGT TATGGTGACA GAAGATGAAG AGGCAATTCA GCAGTATGGA 
AGTGAAACAG AAGGAGTATT CGTGATTACT TTCAAGAATT ACCTGGACAA TTTCTGGCCT 
GATTTAAAAG CTGCCCACGA GCTTTGTGAT TCTATCCTTC AGTCTCGACG GGAGAGAGAG 
AATGAGAGTC AGGAGAGCCA TGGGAAGGAG TACCCAGAAC ATCTTCCCCT GGAAGTGTTA 
GAAGCTGGGA TTAAATCTGG ACGCTATATC CAGGGAATTC TGAATGTCAA CAAACACAGA 
GCCCAAATAG AAGCTTTTGT TCGACTTCAA GGAGCCAGCA GTAAAGATTC AGATTTAGTC 
AGTGACATCC TAATCCACGG GATGAAGGCT CGAAACCGCT CAATTCATGG AGATGTGGTA 
GTTGTGGAGC TGCTTCCTAA AAATGAATGG AAAGGAAGAA CCGTAGCCCT GTGTGAGAAT 
GACTGTGACG ACAAGGCTTC GGGCGAGTCC CCAAGTGAGC CCATGCCTAC AGGTCGAGTG 
GTGGGCATAC TTCAGAAGAA CTGGCGGGAT TATGTGGTGA CATTTCCGTC CAAAGAAGAG 
GTCCAATCTC AGGGCAAAAA TGCTCAGAAA ATCCTGGTTA CACCTTGGGA TTACAGAATT 
CCCAAAATTC GAATTAGCAC TCAGCAAGCA GAAACCCTCC AGGACTTCAG GGTGGTCGTG 
CGCATCGATT CCTGGGAGTC AACATCTGTG TATCCAAATG GACATTTTGT GCGTGTTTTA 
GGAAGAATCG GAGATCTGGA AGGGGAAATT GCAACCATCC TGGTGGAAAA CAGTATTTCA 
GTTATTCCTT TCTCAGAAGC TCAGATGTGT GAGATGCCAG TAAACACACC AGAAAGTCCC 
TGGAAGGTGA GTCCTGAAGA GGAACAAAAA CGTAAAGACT TGAGGAAAAG CCATCTCGTA 
TTCAGCATTG ACCCCAAAGG TTGTGAAGAT GTGGATGACA CACTCTCAGT CAGAACCTTA 
AATAATGGCA ACCTGGAACT TGGGGTCCAC ATCGCAGATG TAACACACTT TGTGGCACCA 
AATTCTTACA TTGATATTGA AGCTAGAACA AGGGCCACCA CTTATTATCT AGCAGATCGT 
CGCTATGACA TGCTGCCTTC CGTCCTCAGT GCAGATTTGT GTTCCCTTCT GGGAGGCGTT 
GATAGGTATG CTGTAAGCAT CATGTGGGAA CTGGATAAAG CCTCTTATGA AATTAAGAAA 
GTGTGGTATG GCAGAACCAT TATTCGATCA GCATACAAAC TGTTCTATGA AGCAGCCCAA 
GAACTACTGG ATGGAAACTT AAGCGTTGTT GATGATATTC CAGAATTCAA AGACTTGGAT 
GAGAAGAGCA GACAAGCCAA GCTGGAGGAG TTGGTGTGGG CAATTGGAAA GCTGACCGAC 
ATAGCTCGCC ATGTCAGAGC TAAACGAGAC GGATGTGGTG CCCTGGAACT GGAAGGGGTA 
GAGGTTTGCG TACAGCTAGA TGACAAAAAG AACATTCACG ACCTCATCCC CAAGCAGCCC 
CTGGAAGTCC ACGAGACAGT GGCTGAATGC ATGATCCTGG CCAACCACTG GGTCGCCAAA 
AAGATCTGGG AGAGCTTCCC TCATCAGGCC TTGCTGCGCC AGCACCCTCC TCCACACCAG 
GAGTTCTTTT CAGAACTCCG GGAATGTGCT AAAGCCAAAG GCTTCTTCAT AGATACACGG 
TCCAATAAAA CACTGGCTGA TTCTCTGGAT AATGCGAACG ACCCCCACGA TCCCATTGTG 
AACAGGCTAC TGCGCTCCAT GGCCACGCAG GCCATGTCGA ATGCTCTGTA CTTCTCCACC 
GGATCCTGTG CGGAGGAGGA GTTCCATCAT TACGGTCTTG CATTAGATAA ATATACCCAC 
TTTACTTCTC CAATAAGAAG ATATTCAGAT ATTGTAGTAC ACCGCTTGTT AATGGCAGCC 
ATTTCAAAAG ATAAGAAAAT GGAAATTAAG GGAAATCTGT TCAGCAACAA AGATCTTGAG 
GAATTATGCA GACATATCAA CAACAGAAAC CAAGCAGCAC AGCATTCTCA GAAGCAGTCT 
ACTGAGCTCT TCCAGTGCAT GTACTTCAAA GACAAAGACC CTGCCACCGA GGAGCGTTGC 
ATATCTGACG GAGTTATTTA TTCAATTAGA ACAAATGGTG TGCTTCTATT TATACCAAGG 
TTTGGGATTA AAGGTGCTGC TTATCTAAAA AATAAAGATG GTTTAGTCAT CTCATGTGGC 
CCAGATAGCT GTTCTGAATG GAAACCAGGA TCCCTTCAAC GATTTCAAAA CAAAATTACC 
TCTACTACAA CAGATGGGGA ATCTGTTACG TTCCATTTGT TTGACCATGT AACCGTAAGA 
ATATCCATAC AGGCCTCACG TTGCCATTCT GATACAATCA GACTTGAAAT AATTAGTAAC 
AAACCATACA AGATACCAAA TACAGAACTT ATTCATCAGA GTTCCCCCTT GCTGAAGAGT 
GAGTTAGTGA AAGAAGTAAC TAAATCTGTG GAAGAAGCTC AGCTTGCCCA AGAAGTCAAA 
GTAAACATCA TTCAGGAGGA ATATCAAGAA TATCGCCAAA CAAAGGGAAG GAGCCTATAC 
ACACTTCTAG AGGAGATACG GGACCTAGCT CTCCTGGATG TTTCAAACAA TTATGGAATA 
TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001310875.1
CDS	546..3308
Translation	MEKWQTRSIYNAAVWYYHHCQDRMPIVMVTEDEEAIQQYGSETEGVFVITFKNYLDNFWPDLKAAHELCDSILQSRRERENESQESHGKEYPEHLPLEVLEAGIKSGRYIQGILNVNKHRAQIEAFVRLQGASSKDSDLVSDILIHGMKARNRSIHGDVVVVELLPKNEWKGRTVALCENDCDDKASGESPSEPMPTGRVVGILQKNWRDYVVTFPSKEEVQSQGKNAQKILVTPWDYRIPKIRISTQQAETLQDFRVVVRIDSWESTSVYPNGHFVRVLGRIGDLEGEIATILVENSISVIPFSEAQMCEMPVNTPESPWKVSPEEEQKRKDLRKSHLVFSIDPKGCEDVDDTLSVRTLNNGNLELGVHIADVTHFVAPNSYIDIEARTRATTYYLADRRYDMLPSVLSADLCSLLGGVDRYAVSIMWELDKASYEIKKVWYGRTIIRSAYKLFYEAAQELLDGNLSVVDDIPEFKDLDEKSRQAKLEELVWAIGKLTDIARHVRAKRDGCGALELEGVEVCVQLDDKKNIHDLIPKQPLEVHETVAECMILANHWVAKKIWESFPHQALLRQHPPPHQEFFSELRECAKAKGFFIDTRSNKTLADSLDNANDPHDPIVNRLLRSMATQAMSNALYFSTGSCAEEEFHHYGLALDKYTHFTSPIRRYSDIVVHRLLMAAISKDKKMEIKGNLFSNKDLEELCRHINNRNQAAQHSQKQSTELFQCMYFKDKDPATEERCISDGVIYSIRTNGVLLFIPRFGIKGAAYLKNKDGLVISCGPDSCSEWKPGSLQRFQNKITSTTTDGESVTFHLFDHVTVRISIQASRCHSDTIRLEIISNKPYKIPNTELIHQSSPLLKSELVKEVTKSVEEAQLAQEVKVNIIQEEYQEYRQTKGRSLYTLLEEIRDLALLDVSNNYGI

Target ORF information:

RefSeq Version	NM_001323946.1
Organism	Homo sapiens(human)
Definition	Homo sapiens DIS3 like exosome 3'-5' exoribonuclease (DIS3L), transcript variant 12, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001323946.1

ORF Insert Sequence:

ATGGAGAAGT GGCAGACCAG GAGCATATAC AACGCAGCTG TTTGGTACTA TCATCACTGC 
CAGGACAGGA TGCCAATTGT TATGGTGACA GAAGATGAAG AGGCAATTCA GCAGTATGGA 
AGTGAAACAG AAGGAGTATT CGTGATTACT TTCAAGAATT ACCTGGACAA TTTCTGGCCT 
GATTTAAAAG CTGCCCACGA GCTTTGTGAT TCTATCCTTC AGTCTCGACG GGAGAGAGAG 
AATGAGAGTC AGGAGAGCCA TGGGAAGGAG TACCCAGAAC ATCTTCCCCT GGAAGTGTTA 
GAAGCTGGGA TTAAATCTGG ACGCTATATC CAGGGAATTC TGAATGTCAA CAAACACAGA 
GCCCAAATAG AAGCTTTTGT TCGACTTCAA GGAGCCAGCA GTAAAGATTC AGATTTAGTC 
AGTGACATCC TAATCCACGG GATGAAGGCT CGAAACCGCT CAATTCATGG AGATGTGGTA 
GTTGTGGAGC TGCTTCCTAA AAATGAATGG AAAGGAAGAA CCGTAGCCCT GTGTGAGAAT 
GACTGTGACG ACAAGGCTTC GGGCGAGTCC CCAAGTGAGC CCATGCCTAC AGGTCGAGTG 
GTGGGCATAC TTCAGAAGAA CTGGCGGGAT TATGTGGTGA CATTTCCGTC CAAAGAAGAG 
GTCCAATCTC AGGGCAAAAA TGCTCAGAAA ATCCTGGTTA CACCTTGGGA TTACAGAATT 
CCCAAAATTC GAATTAGCAC TCAGCAAGCA GAAACCCTCC AGGACTTCAG GGTGGTCGTG 
CGCATCGATT CCTGGGAGTC AACATCTGTG TATCCAAATG GACATTTTGT GCGTGTTTTA 
GGAAGAATCG GAGATCTGGA AGGGGAAATT GCAACCATCC TGGTGGAAAA CAGTATTTCA 
GTTATTCCTT TCTCAGAAGC TCAGATGTGT GAGATGCCAG TAAACACACC AGAAAGTCCC 
TGGAAGGTGA GTCCTGAAGA GGAACAAAAA CGTAAAGACT TGAGGAAAAG CCATCTCGTA 
TTCAGCATTG ACCCCAAAGG TTGTGAAGAT GTGGATGACA CACTCTCAGT CAGAACCTTA 
AATAATGGCA ACCTGGAACT TGGGGTCCAC ATCGCAGATG TAACACACTT TGTGGCACCA 
AATTCTTACA TTGATATTGA AGCTAGAACA AGGGCCACCA CTTATTATCT AGCAGATCGT 
CGCTATGACA TGCTGCCTTC CGTCCTCAGT GCAGATTTGT GTTCCCTTCT GGGAGGCGTT 
GATAGGTATG CTGTAAGCAT CATGTGGGAA CTGGATAAAG CCTCTTATGA AATTAAGAAA 
GTGTGGTATG GCAGAACCAT TATTCGATCA GCATACAAAC TGTTCTATGA AGCAGCCCAA 
GAACTACTGG ATGGAAACTT AAGCGTTGTT GATGATATTC CAGAATTCAA AGACTTGGAT 
GAGAAGAGCA GACAAGCCAA GCTGGAGGAG TTGGTGTGGG CAATTGGAAA GCTGACCGAC 
ATAGCTCGCC ATGTCAGAGC TAAACGAGAC GGATGTGGTG CCCTGGAACT GGAAGGGGTA 
GAGGTTTGCG TACAGCTAGA TGACAAAAAG AACATTCACG ACCTCATCCC CAAGCAGCCC 
CTGGAAGTCC ACGAGACAGT GGCTGAATGC ATGATCCTGG CCAACCACTG GGTCGCCAAA 
AAGATCTGGG AGAGCTTCCC TCATCAGGCC TTGCTGCGCC AGCACCCTCC TCCACACCAG 
GAGTTCTTTT CAGAACTCCG GGAATGTGCT AAAGCCAAAG GCTTCTTCAT AGATACACGG 
TCCAATAAAA CACTGGCTGA TTCTCTGGAT AATGCGAACG ACCCCCACGA TCCCATTGTG 
AACAGGCTAC TGCGCTCCAT GGCCACGCAG GCCATGTCGA ATGCTCTGTA CTTCTCCACC 
GGATCCTGTG CGGAGGAGGA GTTCCATCAT TACGGTCTTG CATTAGATAA ATATACCCAC 
TTTACTTCTC CAATAAGAAG ATATTCAGAT ATTGTAGTAC ACCGCTTGTT AATGGCAGCC 
ATTTCAAAAG ATAAGAAAAT GGAAATTAAG GGAAATCTGT TCAGCAACAA AGATCTTGAG 
GAATTATGCA GACATATCAA CAACAGAAAC CAAGCAGCAC AGCATTCTCA GAAGCAGTCT 
ACTGAGCTCT TCCAGTGCAT GTACTTCAAA GACAAAGACC CTGCCACCGA GGAGCGTTGC 
ATATCTGACG GAGTTATTTA TTCAATTAGA ACAAATGGTG TGCTTCTATT TATACCAAGG 
TTTGGGATTA AAGGTGCTGC TTATCTAAAA AATAAAGATG GTTTAGTCAT CTCATGTGGC 
CCAGATAGCT GTTCTGAATG GAAACCAGGA TCCCTTCAAC GATTTCAAAA CAAAATTACC 
TCTACTACAA CAGATGGGGA ATCTGTTACG TTCCATTTGT TTGACCATGT AACCGTAAGA 
ATATCCATAC AGGCCTCACG TTGCCATTCT GATACAATCA GACTTGAAAT AATTAGTAAC 
AAACCATACA AGATACCAAA TACAGAACTT ATTCATCAGA GTTCCCCCTT GCTGAAGAGT 
GAGTTAGTGA AAGAAGTAAC TAAATCTGTG GAAGAAGCTC AGCTTGCCCA AGAAGTCAAA 
GTAAACATCA TTCAGGAGGA ATATCAAGAA TATCGCCAAA CAAAGGGAAG GAGCCTATAC 
ACACTTCTAG AGGAGATACG GGACCTAGCT CTCCTGGATG TTTCAAACAA TTATGGAATA 
TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

DIS3L ( NM_001323939.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001310868.1 Homo sapiens DIS3 like exosome 3'-5' exoribonuclease (DIS3L), transcript variant 6, mRNA.

Price & Availability↑

CloneID	OHu82920
Clone ID Related Accession (Same CDS sequence)	NM_001323941.2 , NM_001323938.2 , NM_001323946.1 , NM_001323939.1 , NM_001323939.2 , NM_001323938.1 , NM_001323946.2 , NM_001323941.1
Accession Version	NM_001323939.1	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2763bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2018-12-04
Organism	Homo sapiens(human)
Product	DIS3-like exonuclease 1 isoform 3
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AC055855.9. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. ##Evidence-Data-START## Transcript exon combination :: SRR1803617.25742.1, SRR1803613.56410.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968968, SAMEA2147920 [ECO:0000348] ##Evidence-Data-END##

ATGGAGAAGT GGCAGACCAG GAGCATATAC AACGCAGCTG TTTGGTACTA TCATCACTGC 
CAGGACAGGA TGCCAATTGT TATGGTGACA GAAGATGAAG AGGCAATTCA GCAGTATGGA 
AGTGAAACAG AAGGAGTATT CGTGATTACT TTCAAGAATT ACCTGGACAA TTTCTGGCCT 
GATTTAAAAG CTGCCCACGA GCTTTGTGAT TCTATCCTTC AGTCTCGACG GGAGAGAGAG 
AATGAGAGTC AGGAGAGCCA TGGGAAGGAG TACCCAGAAC ATCTTCCCCT GGAAGTGTTA 
GAAGCTGGGA TTAAATCTGG ACGCTATATC CAGGGAATTC TGAATGTCAA CAAACACAGA 
GCCCAAATAG AAGCTTTTGT TCGACTTCAA GGAGCCAGCA GTAAAGATTC AGATTTAGTC 
AGTGACATCC TAATCCACGG GATGAAGGCT CGAAACCGCT CAATTCATGG AGATGTGGTA 
GTTGTGGAGC TGCTTCCTAA AAATGAATGG AAAGGAAGAA CCGTAGCCCT GTGTGAGAAT 
GACTGTGACG ACAAGGCTTC GGGCGAGTCC CCAAGTGAGC CCATGCCTAC AGGTCGAGTG 
GTGGGCATAC TTCAGAAGAA CTGGCGGGAT TATGTGGTGA CATTTCCGTC CAAAGAAGAG 
GTCCAATCTC AGGGCAAAAA TGCTCAGAAA ATCCTGGTTA CACCTTGGGA TTACAGAATT 
CCCAAAATTC GAATTAGCAC TCAGCAAGCA GAAACCCTCC AGGACTTCAG GGTGGTCGTG 
CGCATCGATT CCTGGGAGTC AACATCTGTG TATCCAAATG GACATTTTGT GCGTGTTTTA 
GGAAGAATCG GAGATCTGGA AGGGGAAATT GCAACCATCC TGGTGGAAAA CAGTATTTCA 
GTTATTCCTT TCTCAGAAGC TCAGATGTGT GAGATGCCAG TAAACACACC AGAAAGTCCC 
TGGAAGGTGA GTCCTGAAGA GGAACAAAAA CGTAAAGACT TGAGGAAAAG CCATCTCGTA 
TTCAGCATTG ACCCCAAAGG TTGTGAAGAT GTGGATGACA CACTCTCAGT CAGAACCTTA 
AATAATGGCA ACCTGGAACT TGGGGTCCAC ATCGCAGATG TAACACACTT TGTGGCACCA 
AATTCTTACA TTGATATTGA AGCTAGAACA AGGGCCACCA CTTATTATCT AGCAGATCGT 
CGCTATGACA TGCTGCCTTC CGTCCTCAGT GCAGATTTGT GTTCCCTTCT GGGAGGCGTT 
GATAGGTATG CTGTAAGCAT CATGTGGGAA CTGGATAAAG CCTCTTATGA AATTAAGAAA 
GTGTGGTATG GCAGAACCAT TATTCGATCA GCATACAAAC TGTTCTATGA AGCAGCCCAA 
GAACTACTGG ATGGAAACTT AAGCGTTGTT GATGATATTC CAGAATTCAA AGACTTGGAT 
GAGAAGAGCA GACAAGCCAA GCTGGAGGAG TTGGTGTGGG CAATTGGAAA GCTGACCGAC 
ATAGCTCGCC ATGTCAGAGC TAAACGAGAC GGATGTGGTG CCCTGGAACT GGAAGGGGTA 
GAGGTTTGCG TACAGCTAGA TGACAAAAAG AACATTCACG ACCTCATCCC CAAGCAGCCC 
CTGGAAGTCC ACGAGACAGT GGCTGAATGC ATGATCCTGG CCAACCACTG GGTCGCCAAA 
AAGATCTGGG AGAGCTTCCC TCATCAGGCC TTGCTGCGCC AGCACCCTCC TCCACACCAG 
GAGTTCTTTT CAGAACTCCG GGAATGTGCT AAAGCCAAAG GCTTCTTCAT AGATACACGG 
TCCAATAAAA CACTGGCTGA TTCTCTGGAT AATGCGAACG ACCCCCACGA TCCCATTGTG 
AACAGGCTAC TGCGCTCCAT GGCCACGCAG GCCATGTCGA ATGCTCTGTA CTTCTCCACC 
GGATCCTGTG CGGAGGAGGA GTTCCATCAT TACGGTCTTG CATTAGATAA ATATACCCAC 
TTTACTTCTC CAATAAGAAG ATATTCAGAT ATTGTAGTAC ACCGCTTGTT AATGGCAGCC 
ATTTCAAAAG ATAAGAAAAT GGAAATTAAG GGAAATCTGT TCAGCAACAA AGATCTTGAG 
GAATTATGCA GACATATCAA CAACAGAAAC CAAGCAGCAC AGCATTCTCA GAAGCAGTCT 
ACTGAGCTCT TCCAGTGCAT GTACTTCAAA GACAAAGACC CTGCCACCGA GGAGCGTTGC 
ATATCTGACG GAGTTATTTA TTCAATTAGA ACAAATGGTG TGCTTCTATT TATACCAAGG 
TTTGGGATTA AAGGTGCTGC TTATCTAAAA AATAAAGATG GTTTAGTCAT CTCATGTGGC 
CCAGATAGCT GTTCTGAATG GAAACCAGGA TCCCTTCAAC GATTTCAAAA CAAAATTACC 
TCTACTACAA CAGATGGGGA ATCTGTTACG TTCCATTTGT TTGACCATGT AACCGTAAGA 
ATATCCATAC AGGCCTCACG TTGCCATTCT GATACAATCA GACTTGAAAT AATTAGTAAC 
AAACCATACA AGATACCAAA TACAGAACTT ATTCATCAGA GTTCCCCCTT GCTGAAGAGT 
GAGTTAGTGA AAGAAGTAAC TAAATCTGTG GAAGAAGCTC AGCTTGCCCA AGAAGTCAAA 
GTAAACATCA TTCAGGAGGA ATATCAAGAA TATCGCCAAA CAAAGGGAAG GAGCCTATAC 
ACACTTCTAG AGGAGATACG GGACCTAGCT CTCCTGGATG TTTCAAACAA TTATGGAATA 
TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001310868.1
CDS	549..3311
Translation	MEKWQTRSIYNAAVWYYHHCQDRMPIVMVTEDEEAIQQYGSETEGVFVITFKNYLDNFWPDLKAAHELCDSILQSRRERENESQESHGKEYPEHLPLEVLEAGIKSGRYIQGILNVNKHRAQIEAFVRLQGASSKDSDLVSDILIHGMKARNRSIHGDVVVVELLPKNEWKGRTVALCENDCDDKASGESPSEPMPTGRVVGILQKNWRDYVVTFPSKEEVQSQGKNAQKILVTPWDYRIPKIRISTQQAETLQDFRVVVRIDSWESTSVYPNGHFVRVLGRIGDLEGEIATILVENSISVIPFSEAQMCEMPVNTPESPWKVSPEEEQKRKDLRKSHLVFSIDPKGCEDVDDTLSVRTLNNGNLELGVHIADVTHFVAPNSYIDIEARTRATTYYLADRRYDMLPSVLSADLCSLLGGVDRYAVSIMWELDKASYEIKKVWYGRTIIRSAYKLFYEAAQELLDGNLSVVDDIPEFKDLDEKSRQAKLEELVWAIGKLTDIARHVRAKRDGCGALELEGVEVCVQLDDKKNIHDLIPKQPLEVHETVAECMILANHWVAKKIWESFPHQALLRQHPPPHQEFFSELRECAKAKGFFIDTRSNKTLADSLDNANDPHDPIVNRLLRSMATQAMSNALYFSTGSCAEEEFHHYGLALDKYTHFTSPIRRYSDIVVHRLLMAAISKDKKMEIKGNLFSNKDLEELCRHINNRNQAAQHSQKQSTELFQCMYFKDKDPATEERCISDGVIYSIRTNGVLLFIPRFGIKGAAYLKNKDGLVISCGPDSCSEWKPGSLQRFQNKITSTTTDGESVTFHLFDHVTVRISIQASRCHSDTIRLEIISNKPYKIPNTELIHQSSPLLKSELVKEVTKSVEEAQLAQEVKVNIIQEEYQEYRQTKGRSLYTLLEEIRDLALLDVSNNYGI

Target ORF information:

RefSeq Version	NM_001323939.1
Organism	Homo sapiens(human)
Definition	Homo sapiens DIS3 like exosome 3'-5' exoribonuclease (DIS3L), transcript variant 6, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001323939.1

ORF Insert Sequence:

ATGGAGAAGT GGCAGACCAG GAGCATATAC AACGCAGCTG TTTGGTACTA TCATCACTGC 
CAGGACAGGA TGCCAATTGT TATGGTGACA GAAGATGAAG AGGCAATTCA GCAGTATGGA 
AGTGAAACAG AAGGAGTATT CGTGATTACT TTCAAGAATT ACCTGGACAA TTTCTGGCCT 
GATTTAAAAG CTGCCCACGA GCTTTGTGAT TCTATCCTTC AGTCTCGACG GGAGAGAGAG 
AATGAGAGTC AGGAGAGCCA TGGGAAGGAG TACCCAGAAC ATCTTCCCCT GGAAGTGTTA 
GAAGCTGGGA TTAAATCTGG ACGCTATATC CAGGGAATTC TGAATGTCAA CAAACACAGA 
GCCCAAATAG AAGCTTTTGT TCGACTTCAA GGAGCCAGCA GTAAAGATTC AGATTTAGTC 
AGTGACATCC TAATCCACGG GATGAAGGCT CGAAACCGCT CAATTCATGG AGATGTGGTA 
GTTGTGGAGC TGCTTCCTAA AAATGAATGG AAAGGAAGAA CCGTAGCCCT GTGTGAGAAT 
GACTGTGACG ACAAGGCTTC GGGCGAGTCC CCAAGTGAGC CCATGCCTAC AGGTCGAGTG 
GTGGGCATAC TTCAGAAGAA CTGGCGGGAT TATGTGGTGA CATTTCCGTC CAAAGAAGAG 
GTCCAATCTC AGGGCAAAAA TGCTCAGAAA ATCCTGGTTA CACCTTGGGA TTACAGAATT 
CCCAAAATTC GAATTAGCAC TCAGCAAGCA GAAACCCTCC AGGACTTCAG GGTGGTCGTG 
CGCATCGATT CCTGGGAGTC AACATCTGTG TATCCAAATG GACATTTTGT GCGTGTTTTA 
GGAAGAATCG GAGATCTGGA AGGGGAAATT GCAACCATCC TGGTGGAAAA CAGTATTTCA 
GTTATTCCTT TCTCAGAAGC TCAGATGTGT GAGATGCCAG TAAACACACC AGAAAGTCCC 
TGGAAGGTGA GTCCTGAAGA GGAACAAAAA CGTAAAGACT TGAGGAAAAG CCATCTCGTA 
TTCAGCATTG ACCCCAAAGG TTGTGAAGAT GTGGATGACA CACTCTCAGT CAGAACCTTA 
AATAATGGCA ACCTGGAACT TGGGGTCCAC ATCGCAGATG TAACACACTT TGTGGCACCA 
AATTCTTACA TTGATATTGA AGCTAGAACA AGGGCCACCA CTTATTATCT AGCAGATCGT 
CGCTATGACA TGCTGCCTTC CGTCCTCAGT GCAGATTTGT GTTCCCTTCT GGGAGGCGTT 
GATAGGTATG CTGTAAGCAT CATGTGGGAA CTGGATAAAG CCTCTTATGA AATTAAGAAA 
GTGTGGTATG GCAGAACCAT TATTCGATCA GCATACAAAC TGTTCTATGA AGCAGCCCAA 
GAACTACTGG ATGGAAACTT AAGCGTTGTT GATGATATTC CAGAATTCAA AGACTTGGAT 
GAGAAGAGCA GACAAGCCAA GCTGGAGGAG TTGGTGTGGG CAATTGGAAA GCTGACCGAC 
ATAGCTCGCC ATGTCAGAGC TAAACGAGAC GGATGTGGTG CCCTGGAACT GGAAGGGGTA 
GAGGTTTGCG TACAGCTAGA TGACAAAAAG AACATTCACG ACCTCATCCC CAAGCAGCCC 
CTGGAAGTCC ACGAGACAGT GGCTGAATGC ATGATCCTGG CCAACCACTG GGTCGCCAAA 
AAGATCTGGG AGAGCTTCCC TCATCAGGCC TTGCTGCGCC AGCACCCTCC TCCACACCAG 
GAGTTCTTTT CAGAACTCCG GGAATGTGCT AAAGCCAAAG GCTTCTTCAT AGATACACGG 
TCCAATAAAA CACTGGCTGA TTCTCTGGAT AATGCGAACG ACCCCCACGA TCCCATTGTG 
AACAGGCTAC TGCGCTCCAT GGCCACGCAG GCCATGTCGA ATGCTCTGTA CTTCTCCACC 
GGATCCTGTG CGGAGGAGGA GTTCCATCAT TACGGTCTTG CATTAGATAA ATATACCCAC 
TTTACTTCTC CAATAAGAAG ATATTCAGAT ATTGTAGTAC ACCGCTTGTT AATGGCAGCC 
ATTTCAAAAG ATAAGAAAAT GGAAATTAAG GGAAATCTGT TCAGCAACAA AGATCTTGAG 
GAATTATGCA GACATATCAA CAACAGAAAC CAAGCAGCAC AGCATTCTCA GAAGCAGTCT 
ACTGAGCTCT TCCAGTGCAT GTACTTCAAA GACAAAGACC CTGCCACCGA GGAGCGTTGC 
ATATCTGACG GAGTTATTTA TTCAATTAGA ACAAATGGTG TGCTTCTATT TATACCAAGG 
TTTGGGATTA AAGGTGCTGC TTATCTAAAA AATAAAGATG GTTTAGTCAT CTCATGTGGC 
CCAGATAGCT GTTCTGAATG GAAACCAGGA TCCCTTCAAC GATTTCAAAA CAAAATTACC 
TCTACTACAA CAGATGGGGA ATCTGTTACG TTCCATTTGT TTGACCATGT AACCGTAAGA 
ATATCCATAC AGGCCTCACG TTGCCATTCT GATACAATCA GACTTGAAAT AATTAGTAAC 
AAACCATACA AGATACCAAA TACAGAACTT ATTCATCAGA GTTCCCCCTT GCTGAAGAGT 
GAGTTAGTGA AAGAAGTAAC TAAATCTGTG GAAGAAGCTC AGCTTGCCCA AGAAGTCAAA 
GTAAACATCA TTCAGGAGGA ATATCAAGAA TATCGCCAAA CAAAGGGAAG GAGCCTATAC 
ACACTTCTAG AGGAGATACG GGACCTAGCT CTCCTGGATG TTTCAAACAA TTATGGAATA 
TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

DIS3L ( NM_001323939.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_001310868.1 Homo sapiens DIS3 like exosome 3'-5' exoribonuclease (DIS3L), transcript variant 6, mRNA.

Price & Availability↑

CloneID	OHu82920
Clone ID Related Accession (Same CDS sequence)	NM_001323941.2 , NM_001323938.2 , NM_001323946.1 , NM_001323939.1 , NM_001323939.2 , NM_001323938.1 , NM_001323946.2 , NM_001323941.1
Accession Version	NM_001323939.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2763bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-09-27
Organism	Homo sapiens(human)
Product	DIS3-like exonuclease 1 isoform 3
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AC055855.9. On May 31, 2019 this sequence version replaced NM_001323939.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. ##Evidence-Data-START## Transcript exon combination :: SRR1803613.56410.1, SRR1803616.228445.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968968, SAMEA2147920 [ECO:0000348] ##Evidence-Data-END##

ATGGAGAAGT GGCAGACCAG GAGCATATAC AACGCAGCTG TTTGGTACTA TCATCACTGC 
CAGGACAGGA TGCCAATTGT TATGGTGACA GAAGATGAAG AGGCAATTCA GCAGTATGGA 
AGTGAAACAG AAGGAGTATT CGTGATTACT TTCAAGAATT ACCTGGACAA TTTCTGGCCT 
GATTTAAAAG CTGCCCACGA GCTTTGTGAT TCTATCCTTC AGTCTCGACG GGAGAGAGAG 
AATGAGAGTC AGGAGAGCCA TGGGAAGGAG TACCCAGAAC ATCTTCCCCT GGAAGTGTTA 
GAAGCTGGGA TTAAATCTGG ACGCTATATC CAGGGAATTC TGAATGTCAA CAAACACAGA 
GCCCAAATAG AAGCTTTTGT TCGACTTCAA GGAGCCAGCA GTAAAGATTC AGATTTAGTC 
AGTGACATCC TAATCCACGG GATGAAGGCT CGAAACCGCT CAATTCATGG AGATGTGGTA 
GTTGTGGAGC TGCTTCCTAA AAATGAATGG AAAGGAAGAA CCGTAGCCCT GTGTGAGAAT 
GACTGTGACG ACAAGGCTTC GGGCGAGTCC CCAAGTGAGC CCATGCCTAC AGGTCGAGTG 
GTGGGCATAC TTCAGAAGAA CTGGCGGGAT TATGTGGTGA CATTTCCGTC CAAAGAAGAG 
GTCCAATCTC AGGGCAAAAA TGCTCAGAAA ATCCTGGTTA CACCTTGGGA TTACAGAATT 
CCCAAAATTC GAATTAGCAC TCAGCAAGCA GAAACCCTCC AGGACTTCAG GGTGGTCGTG 
CGCATCGATT CCTGGGAGTC AACATCTGTG TATCCAAATG GACATTTTGT GCGTGTTTTA 
GGAAGAATCG GAGATCTGGA AGGGGAAATT GCAACCATCC TGGTGGAAAA CAGTATTTCA 
GTTATTCCTT TCTCAGAAGC TCAGATGTGT GAGATGCCAG TAAACACACC AGAAAGTCCC 
TGGAAGGTGA GTCCTGAAGA GGAACAAAAA CGTAAAGACT TGAGGAAAAG CCATCTCGTA 
TTCAGCATTG ACCCCAAAGG TTGTGAAGAT GTGGATGACA CACTCTCAGT CAGAACCTTA 
AATAATGGCA ACCTGGAACT TGGGGTCCAC ATCGCAGATG TAACACACTT TGTGGCACCA 
AATTCTTACA TTGATATTGA AGCTAGAACA AGGGCCACCA CTTATTATCT AGCAGATCGT 
CGCTATGACA TGCTGCCTTC CGTCCTCAGT GCAGATTTGT GTTCCCTTCT GGGAGGCGTT 
GATAGGTATG CTGTAAGCAT CATGTGGGAA CTGGATAAAG CCTCTTATGA AATTAAGAAA 
GTGTGGTATG GCAGAACCAT TATTCGATCA GCATACAAAC TGTTCTATGA AGCAGCCCAA 
GAACTACTGG ATGGAAACTT AAGCGTTGTT GATGATATTC CAGAATTCAA AGACTTGGAT 
GAGAAGAGCA GACAAGCCAA GCTGGAGGAG TTGGTGTGGG CAATTGGAAA GCTGACCGAC 
ATAGCTCGCC ATGTCAGAGC TAAACGAGAC GGATGTGGTG CCCTGGAACT GGAAGGGGTA 
GAGGTTTGCG TACAGCTAGA TGACAAAAAG AACATTCACG ACCTCATCCC CAAGCAGCCC 
CTGGAAGTCC ACGAGACAGT GGCTGAATGC ATGATCCTGG CCAACCACTG GGTCGCCAAA 
AAGATCTGGG AGAGCTTCCC TCATCAGGCC TTGCTGCGCC AGCACCCTCC TCCACACCAG 
GAGTTCTTTT CAGAACTCCG GGAATGTGCT AAAGCCAAAG GCTTCTTCAT AGATACACGG 
TCCAATAAAA CACTGGCTGA TTCTCTGGAT AATGCGAACG ACCCCCACGA TCCCATTGTG 
AACAGGCTAC TGCGCTCCAT GGCCACGCAG GCCATGTCGA ATGCTCTGTA CTTCTCCACC 
GGATCCTGTG CGGAGGAGGA GTTCCATCAT TACGGTCTTG CATTAGATAA ATATACCCAC 
TTTACTTCTC CAATAAGAAG ATATTCAGAT ATTGTAGTAC ACCGCTTGTT AATGGCAGCC 
ATTTCAAAAG ATAAGAAAAT GGAAATTAAG GGAAATCTGT TCAGCAACAA AGATCTTGAG 
GAATTATGCA GACATATCAA CAACAGAAAC CAAGCAGCAC AGCATTCTCA GAAGCAGTCT 
ACTGAGCTCT TCCAGTGCAT GTACTTCAAA GACAAAGACC CTGCCACCGA GGAGCGTTGC 
ATATCTGACG GAGTTATTTA TTCAATTAGA ACAAATGGTG TGCTTCTATT TATACCAAGG 
TTTGGGATTA AAGGTGCTGC TTATCTAAAA AATAAAGATG GTTTAGTCAT CTCATGTGGC 
CCAGATAGCT GTTCTGAATG GAAACCAGGA TCCCTTCAAC GATTTCAAAA CAAAATTACC 
TCTACTACAA CAGATGGGGA ATCTGTTACG TTCCATTTGT TTGACCATGT AACCGTAAGA 
ATATCCATAC AGGCCTCACG TTGCCATTCT GATACAATCA GACTTGAAAT AATTAGTAAC 
AAACCATACA AGATACCAAA TACAGAACTT ATTCATCAGA GTTCCCCCTT GCTGAAGAGT 
GAGTTAGTGA AAGAAGTAAC TAAATCTGTG GAAGAAGCTC AGCTTGCCCA AGAAGTCAAA 
GTAAACATCA TTCAGGAGGA ATATCAAGAA TATCGCCAAA CAAAGGGAAG GAGCCTATAC 
ACACTTCTAG AGGAGATACG GGACCTAGCT CTCCTGGATG TTTCAAACAA TTATGGAATA 
TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001310868.1
CDS	556..3318
Translation	MEKWQTRSIYNAAVWYYHHCQDRMPIVMVTEDEEAIQQYGSETEGVFVITFKNYLDNFWPDLKAAHELCDSILQSRRERENESQESHGKEYPEHLPLEVLEAGIKSGRYIQGILNVNKHRAQIEAFVRLQGASSKDSDLVSDILIHGMKARNRSIHGDVVVVELLPKNEWKGRTVALCENDCDDKASGESPSEPMPTGRVVGILQKNWRDYVVTFPSKEEVQSQGKNAQKILVTPWDYRIPKIRISTQQAETLQDFRVVVRIDSWESTSVYPNGHFVRVLGRIGDLEGEIATILVENSISVIPFSEAQMCEMPVNTPESPWKVSPEEEQKRKDLRKSHLVFSIDPKGCEDVDDTLSVRTLNNGNLELGVHIADVTHFVAPNSYIDIEARTRATTYYLADRRYDMLPSVLSADLCSLLGGVDRYAVSIMWELDKASYEIKKVWYGRTIIRSAYKLFYEAAQELLDGNLSVVDDIPEFKDLDEKSRQAKLEELVWAIGKLTDIARHVRAKRDGCGALELEGVEVCVQLDDKKNIHDLIPKQPLEVHETVAECMILANHWVAKKIWESFPHQALLRQHPPPHQEFFSELRECAKAKGFFIDTRSNKTLADSLDNANDPHDPIVNRLLRSMATQAMSNALYFSTGSCAEEEFHHYGLALDKYTHFTSPIRRYSDIVVHRLLMAAISKDKKMEIKGNLFSNKDLEELCRHINNRNQAAQHSQKQSTELFQCMYFKDKDPATEERCISDGVIYSIRTNGVLLFIPRFGIKGAAYLKNKDGLVISCGPDSCSEWKPGSLQRFQNKITSTTTDGESVTFHLFDHVTVRISIQASRCHSDTIRLEIISNKPYKIPNTELIHQSSPLLKSELVKEVTKSVEEAQLAQEVKVNIIQEEYQEYRQTKGRSLYTLLEEIRDLALLDVSNNYGI

Target ORF information:

RefSeq Version	NM_001323939.2
Organism	Homo sapiens(human)
Definition	Homo sapiens DIS3 like exosome 3'-5' exoribonuclease (DIS3L), transcript variant 6, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001323939.2

ORF Insert Sequence:

ATGGAGAAGT GGCAGACCAG GAGCATATAC AACGCAGCTG TTTGGTACTA TCATCACTGC 
CAGGACAGGA TGCCAATTGT TATGGTGACA GAAGATGAAG AGGCAATTCA GCAGTATGGA 
AGTGAAACAG AAGGAGTATT CGTGATTACT TTCAAGAATT ACCTGGACAA TTTCTGGCCT 
GATTTAAAAG CTGCCCACGA GCTTTGTGAT TCTATCCTTC AGTCTCGACG GGAGAGAGAG 
AATGAGAGTC AGGAGAGCCA TGGGAAGGAG TACCCAGAAC ATCTTCCCCT GGAAGTGTTA 
GAAGCTGGGA TTAAATCTGG ACGCTATATC CAGGGAATTC TGAATGTCAA CAAACACAGA 
GCCCAAATAG AAGCTTTTGT TCGACTTCAA GGAGCCAGCA GTAAAGATTC AGATTTAGTC 
AGTGACATCC TAATCCACGG GATGAAGGCT CGAAACCGCT CAATTCATGG AGATGTGGTA 
GTTGTGGAGC TGCTTCCTAA AAATGAATGG AAAGGAAGAA CCGTAGCCCT GTGTGAGAAT 
GACTGTGACG ACAAGGCTTC GGGCGAGTCC CCAAGTGAGC CCATGCCTAC AGGTCGAGTG 
GTGGGCATAC TTCAGAAGAA CTGGCGGGAT TATGTGGTGA CATTTCCGTC CAAAGAAGAG 
GTCCAATCTC AGGGCAAAAA TGCTCAGAAA ATCCTGGTTA CACCTTGGGA TTACAGAATT 
CCCAAAATTC GAATTAGCAC TCAGCAAGCA GAAACCCTCC AGGACTTCAG GGTGGTCGTG 
CGCATCGATT CCTGGGAGTC AACATCTGTG TATCCAAATG GACATTTTGT GCGTGTTTTA 
GGAAGAATCG GAGATCTGGA AGGGGAAATT GCAACCATCC TGGTGGAAAA CAGTATTTCA 
GTTATTCCTT TCTCAGAAGC TCAGATGTGT GAGATGCCAG TAAACACACC AGAAAGTCCC 
TGGAAGGTGA GTCCTGAAGA GGAACAAAAA CGTAAAGACT TGAGGAAAAG CCATCTCGTA 
TTCAGCATTG ACCCCAAAGG TTGTGAAGAT GTGGATGACA CACTCTCAGT CAGAACCTTA 
AATAATGGCA ACCTGGAACT TGGGGTCCAC ATCGCAGATG TAACACACTT TGTGGCACCA 
AATTCTTACA TTGATATTGA AGCTAGAACA AGGGCCACCA CTTATTATCT AGCAGATCGT 
CGCTATGACA TGCTGCCTTC CGTCCTCAGT GCAGATTTGT GTTCCCTTCT GGGAGGCGTT 
GATAGGTATG CTGTAAGCAT CATGTGGGAA CTGGATAAAG CCTCTTATGA AATTAAGAAA 
GTGTGGTATG GCAGAACCAT TATTCGATCA GCATACAAAC TGTTCTATGA AGCAGCCCAA 
GAACTACTGG ATGGAAACTT AAGCGTTGTT GATGATATTC CAGAATTCAA AGACTTGGAT 
GAGAAGAGCA GACAAGCCAA GCTGGAGGAG TTGGTGTGGG CAATTGGAAA GCTGACCGAC 
ATAGCTCGCC ATGTCAGAGC TAAACGAGAC GGATGTGGTG CCCTGGAACT GGAAGGGGTA 
GAGGTTTGCG TACAGCTAGA TGACAAAAAG AACATTCACG ACCTCATCCC CAAGCAGCCC 
CTGGAAGTCC ACGAGACAGT GGCTGAATGC ATGATCCTGG CCAACCACTG GGTCGCCAAA 
AAGATCTGGG AGAGCTTCCC TCATCAGGCC TTGCTGCGCC AGCACCCTCC TCCACACCAG 
GAGTTCTTTT CAGAACTCCG GGAATGTGCT AAAGCCAAAG GCTTCTTCAT AGATACACGG 
TCCAATAAAA CACTGGCTGA TTCTCTGGAT AATGCGAACG ACCCCCACGA TCCCATTGTG 
AACAGGCTAC TGCGCTCCAT GGCCACGCAG GCCATGTCGA ATGCTCTGTA CTTCTCCACC 
GGATCCTGTG CGGAGGAGGA GTTCCATCAT TACGGTCTTG CATTAGATAA ATATACCCAC 
TTTACTTCTC CAATAAGAAG ATATTCAGAT ATTGTAGTAC ACCGCTTGTT AATGGCAGCC 
ATTTCAAAAG ATAAGAAAAT GGAAATTAAG GGAAATCTGT TCAGCAACAA AGATCTTGAG 
GAATTATGCA GACATATCAA CAACAGAAAC CAAGCAGCAC AGCATTCTCA GAAGCAGTCT 
ACTGAGCTCT TCCAGTGCAT GTACTTCAAA GACAAAGACC CTGCCACCGA GGAGCGTTGC 
ATATCTGACG GAGTTATTTA TTCAATTAGA ACAAATGGTG TGCTTCTATT TATACCAAGG 
TTTGGGATTA AAGGTGCTGC TTATCTAAAA AATAAAGATG GTTTAGTCAT CTCATGTGGC 
CCAGATAGCT GTTCTGAATG GAAACCAGGA TCCCTTCAAC GATTTCAAAA CAAAATTACC 
TCTACTACAA CAGATGGGGA ATCTGTTACG TTCCATTTGT TTGACCATGT AACCGTAAGA 
ATATCCATAC AGGCCTCACG TTGCCATTCT GATACAATCA GACTTGAAAT AATTAGTAAC 
AAACCATACA AGATACCAAA TACAGAACTT ATTCATCAGA GTTCCCCCTT GCTGAAGAGT 
GAGTTAGTGA AAGAAGTAAC TAAATCTGTG GAAGAAGCTC AGCTTGCCCA AGAAGTCAAA 
GTAAACATCA TTCAGGAGGA ATATCAAGAA TATCGCCAAA CAAAGGGAAG GAGCCTATAC 
ACACTTCTAG AGGAGATACG GGACCTAGCT CTCCTGGATG TTTCAAACAA TTATGGAATA 
TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

DIS3L ( NM_001323938.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001310867.1 Homo sapiens DIS3 like exosome 3'-5' exoribonuclease (DIS3L), transcript variant 5, mRNA.

Price & Availability↑

CloneID	OHu82920
Clone ID Related Accession (Same CDS sequence)	NM_001323941.2 , NM_001323938.2 , NM_001323946.1 , NM_001323939.1 , NM_001323939.2 , NM_001323938.1 , NM_001323946.2 , NM_001323941.1
Accession Version	NM_001323938.1	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2763bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2018-12-04
Organism	Homo sapiens(human)
Product	DIS3-like exonuclease 1 isoform 3
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AC055855.9. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. ##Evidence-Data-START## Transcript exon combination :: SRR1803612.183177.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1968540 [ECO:0000348] ##Evidence-Data-END##

ATGGAGAAGT GGCAGACCAG GAGCATATAC AACGCAGCTG TTTGGTACTA TCATCACTGC 
CAGGACAGGA TGCCAATTGT TATGGTGACA GAAGATGAAG AGGCAATTCA GCAGTATGGA 
AGTGAAACAG AAGGAGTATT CGTGATTACT TTCAAGAATT ACCTGGACAA TTTCTGGCCT 
GATTTAAAAG CTGCCCACGA GCTTTGTGAT TCTATCCTTC AGTCTCGACG GGAGAGAGAG 
AATGAGAGTC AGGAGAGCCA TGGGAAGGAG TACCCAGAAC ATCTTCCCCT GGAAGTGTTA 
GAAGCTGGGA TTAAATCTGG ACGCTATATC CAGGGAATTC TGAATGTCAA CAAACACAGA 
GCCCAAATAG AAGCTTTTGT TCGACTTCAA GGAGCCAGCA GTAAAGATTC AGATTTAGTC 
AGTGACATCC TAATCCACGG GATGAAGGCT CGAAACCGCT CAATTCATGG AGATGTGGTA 
GTTGTGGAGC TGCTTCCTAA AAATGAATGG AAAGGAAGAA CCGTAGCCCT GTGTGAGAAT 
GACTGTGACG ACAAGGCTTC GGGCGAGTCC CCAAGTGAGC CCATGCCTAC AGGTCGAGTG 
GTGGGCATAC TTCAGAAGAA CTGGCGGGAT TATGTGGTGA CATTTCCGTC CAAAGAAGAG 
GTCCAATCTC AGGGCAAAAA TGCTCAGAAA ATCCTGGTTA CACCTTGGGA TTACAGAATT 
CCCAAAATTC GAATTAGCAC TCAGCAAGCA GAAACCCTCC AGGACTTCAG GGTGGTCGTG 
CGCATCGATT CCTGGGAGTC AACATCTGTG TATCCAAATG GACATTTTGT GCGTGTTTTA 
GGAAGAATCG GAGATCTGGA AGGGGAAATT GCAACCATCC TGGTGGAAAA CAGTATTTCA 
GTTATTCCTT TCTCAGAAGC TCAGATGTGT GAGATGCCAG TAAACACACC AGAAAGTCCC 
TGGAAGGTGA GTCCTGAAGA GGAACAAAAA CGTAAAGACT TGAGGAAAAG CCATCTCGTA 
TTCAGCATTG ACCCCAAAGG TTGTGAAGAT GTGGATGACA CACTCTCAGT CAGAACCTTA 
AATAATGGCA ACCTGGAACT TGGGGTCCAC ATCGCAGATG TAACACACTT TGTGGCACCA 
AATTCTTACA TTGATATTGA AGCTAGAACA AGGGCCACCA CTTATTATCT AGCAGATCGT 
CGCTATGACA TGCTGCCTTC CGTCCTCAGT GCAGATTTGT GTTCCCTTCT GGGAGGCGTT 
GATAGGTATG CTGTAAGCAT CATGTGGGAA CTGGATAAAG CCTCTTATGA AATTAAGAAA 
GTGTGGTATG GCAGAACCAT TATTCGATCA GCATACAAAC TGTTCTATGA AGCAGCCCAA 
GAACTACTGG ATGGAAACTT AAGCGTTGTT GATGATATTC CAGAATTCAA AGACTTGGAT 
GAGAAGAGCA GACAAGCCAA GCTGGAGGAG TTGGTGTGGG CAATTGGAAA GCTGACCGAC 
ATAGCTCGCC ATGTCAGAGC TAAACGAGAC GGATGTGGTG CCCTGGAACT GGAAGGGGTA 
GAGGTTTGCG TACAGCTAGA TGACAAAAAG AACATTCACG ACCTCATCCC CAAGCAGCCC 
CTGGAAGTCC ACGAGACAGT GGCTGAATGC ATGATCCTGG CCAACCACTG GGTCGCCAAA 
AAGATCTGGG AGAGCTTCCC TCATCAGGCC TTGCTGCGCC AGCACCCTCC TCCACACCAG 
GAGTTCTTTT CAGAACTCCG GGAATGTGCT AAAGCCAAAG GCTTCTTCAT AGATACACGG 
TCCAATAAAA CACTGGCTGA TTCTCTGGAT AATGCGAACG ACCCCCACGA TCCCATTGTG 
AACAGGCTAC TGCGCTCCAT GGCCACGCAG GCCATGTCGA ATGCTCTGTA CTTCTCCACC 
GGATCCTGTG CGGAGGAGGA GTTCCATCAT TACGGTCTTG CATTAGATAA ATATACCCAC 
TTTACTTCTC CAATAAGAAG ATATTCAGAT ATTGTAGTAC ACCGCTTGTT AATGGCAGCC 
ATTTCAAAAG ATAAGAAAAT GGAAATTAAG GGAAATCTGT TCAGCAACAA AGATCTTGAG 
GAATTATGCA GACATATCAA CAACAGAAAC CAAGCAGCAC AGCATTCTCA GAAGCAGTCT 
ACTGAGCTCT TCCAGTGCAT GTACTTCAAA GACAAAGACC CTGCCACCGA GGAGCGTTGC 
ATATCTGACG GAGTTATTTA TTCAATTAGA ACAAATGGTG TGCTTCTATT TATACCAAGG 
TTTGGGATTA AAGGTGCTGC TTATCTAAAA AATAAAGATG GTTTAGTCAT CTCATGTGGC 
CCAGATAGCT GTTCTGAATG GAAACCAGGA TCCCTTCAAC GATTTCAAAA CAAAATTACC 
TCTACTACAA CAGATGGGGA ATCTGTTACG TTCCATTTGT TTGACCATGT AACCGTAAGA 
ATATCCATAC AGGCCTCACG TTGCCATTCT GATACAATCA GACTTGAAAT AATTAGTAAC 
AAACCATACA AGATACCAAA TACAGAACTT ATTCATCAGA GTTCCCCCTT GCTGAAGAGT 
GAGTTAGTGA AAGAAGTAAC TAAATCTGTG GAAGAAGCTC AGCTTGCCCA AGAAGTCAAA 
GTAAACATCA TTCAGGAGGA ATATCAAGAA TATCGCCAAA CAAAGGGAAG GAGCCTATAC 
ACACTTCTAG AGGAGATACG GGACCTAGCT CTCCTGGATG TTTCAAACAA TTATGGAATA 
TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001310867.1
CDS	352..3114
Translation	MEKWQTRSIYNAAVWYYHHCQDRMPIVMVTEDEEAIQQYGSETEGVFVITFKNYLDNFWPDLKAAHELCDSILQSRRERENESQESHGKEYPEHLPLEVLEAGIKSGRYIQGILNVNKHRAQIEAFVRLQGASSKDSDLVSDILIHGMKARNRSIHGDVVVVELLPKNEWKGRTVALCENDCDDKASGESPSEPMPTGRVVGILQKNWRDYVVTFPSKEEVQSQGKNAQKILVTPWDYRIPKIRISTQQAETLQDFRVVVRIDSWESTSVYPNGHFVRVLGRIGDLEGEIATILVENSISVIPFSEAQMCEMPVNTPESPWKVSPEEEQKRKDLRKSHLVFSIDPKGCEDVDDTLSVRTLNNGNLELGVHIADVTHFVAPNSYIDIEARTRATTYYLADRRYDMLPSVLSADLCSLLGGVDRYAVSIMWELDKASYEIKKVWYGRTIIRSAYKLFYEAAQELLDGNLSVVDDIPEFKDLDEKSRQAKLEELVWAIGKLTDIARHVRAKRDGCGALELEGVEVCVQLDDKKNIHDLIPKQPLEVHETVAECMILANHWVAKKIWESFPHQALLRQHPPPHQEFFSELRECAKAKGFFIDTRSNKTLADSLDNANDPHDPIVNRLLRSMATQAMSNALYFSTGSCAEEEFHHYGLALDKYTHFTSPIRRYSDIVVHRLLMAAISKDKKMEIKGNLFSNKDLEELCRHINNRNQAAQHSQKQSTELFQCMYFKDKDPATEERCISDGVIYSIRTNGVLLFIPRFGIKGAAYLKNKDGLVISCGPDSCSEWKPGSLQRFQNKITSTTTDGESVTFHLFDHVTVRISIQASRCHSDTIRLEIISNKPYKIPNTELIHQSSPLLKSELVKEVTKSVEEAQLAQEVKVNIIQEEYQEYRQTKGRSLYTLLEEIRDLALLDVSNNYGI

Target ORF information:

RefSeq Version	NM_001323938.1
Organism	Homo sapiens(human)
Definition	Homo sapiens DIS3 like exosome 3'-5' exoribonuclease (DIS3L), transcript variant 5, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001323938.1

ORF Insert Sequence:

ATGGAGAAGT GGCAGACCAG GAGCATATAC AACGCAGCTG TTTGGTACTA TCATCACTGC 
CAGGACAGGA TGCCAATTGT TATGGTGACA GAAGATGAAG AGGCAATTCA GCAGTATGGA 
AGTGAAACAG AAGGAGTATT CGTGATTACT TTCAAGAATT ACCTGGACAA TTTCTGGCCT 
GATTTAAAAG CTGCCCACGA GCTTTGTGAT TCTATCCTTC AGTCTCGACG GGAGAGAGAG 
AATGAGAGTC AGGAGAGCCA TGGGAAGGAG TACCCAGAAC ATCTTCCCCT GGAAGTGTTA 
GAAGCTGGGA TTAAATCTGG ACGCTATATC CAGGGAATTC TGAATGTCAA CAAACACAGA 
GCCCAAATAG AAGCTTTTGT TCGACTTCAA GGAGCCAGCA GTAAAGATTC AGATTTAGTC 
AGTGACATCC TAATCCACGG GATGAAGGCT CGAAACCGCT CAATTCATGG AGATGTGGTA 
GTTGTGGAGC TGCTTCCTAA AAATGAATGG AAAGGAAGAA CCGTAGCCCT GTGTGAGAAT 
GACTGTGACG ACAAGGCTTC GGGCGAGTCC CCAAGTGAGC CCATGCCTAC AGGTCGAGTG 
GTGGGCATAC TTCAGAAGAA CTGGCGGGAT TATGTGGTGA CATTTCCGTC CAAAGAAGAG 
GTCCAATCTC AGGGCAAAAA TGCTCAGAAA ATCCTGGTTA CACCTTGGGA TTACAGAATT 
CCCAAAATTC GAATTAGCAC TCAGCAAGCA GAAACCCTCC AGGACTTCAG GGTGGTCGTG 
CGCATCGATT CCTGGGAGTC AACATCTGTG TATCCAAATG GACATTTTGT GCGTGTTTTA 
GGAAGAATCG GAGATCTGGA AGGGGAAATT GCAACCATCC TGGTGGAAAA CAGTATTTCA 
GTTATTCCTT TCTCAGAAGC TCAGATGTGT GAGATGCCAG TAAACACACC AGAAAGTCCC 
TGGAAGGTGA GTCCTGAAGA GGAACAAAAA CGTAAAGACT TGAGGAAAAG CCATCTCGTA 
TTCAGCATTG ACCCCAAAGG TTGTGAAGAT GTGGATGACA CACTCTCAGT CAGAACCTTA 
AATAATGGCA ACCTGGAACT TGGGGTCCAC ATCGCAGATG TAACACACTT TGTGGCACCA 
AATTCTTACA TTGATATTGA AGCTAGAACA AGGGCCACCA CTTATTATCT AGCAGATCGT 
CGCTATGACA TGCTGCCTTC CGTCCTCAGT GCAGATTTGT GTTCCCTTCT GGGAGGCGTT 
GATAGGTATG CTGTAAGCAT CATGTGGGAA CTGGATAAAG CCTCTTATGA AATTAAGAAA 
GTGTGGTATG GCAGAACCAT TATTCGATCA GCATACAAAC TGTTCTATGA AGCAGCCCAA 
GAACTACTGG ATGGAAACTT AAGCGTTGTT GATGATATTC CAGAATTCAA AGACTTGGAT 
GAGAAGAGCA GACAAGCCAA GCTGGAGGAG TTGGTGTGGG CAATTGGAAA GCTGACCGAC 
ATAGCTCGCC ATGTCAGAGC TAAACGAGAC GGATGTGGTG CCCTGGAACT GGAAGGGGTA 
GAGGTTTGCG TACAGCTAGA TGACAAAAAG AACATTCACG ACCTCATCCC CAAGCAGCCC 
CTGGAAGTCC ACGAGACAGT GGCTGAATGC ATGATCCTGG CCAACCACTG GGTCGCCAAA 
AAGATCTGGG AGAGCTTCCC TCATCAGGCC TTGCTGCGCC AGCACCCTCC TCCACACCAG 
GAGTTCTTTT CAGAACTCCG GGAATGTGCT AAAGCCAAAG GCTTCTTCAT AGATACACGG 
TCCAATAAAA CACTGGCTGA TTCTCTGGAT AATGCGAACG ACCCCCACGA TCCCATTGTG 
AACAGGCTAC TGCGCTCCAT GGCCACGCAG GCCATGTCGA ATGCTCTGTA CTTCTCCACC 
GGATCCTGTG CGGAGGAGGA GTTCCATCAT TACGGTCTTG CATTAGATAA ATATACCCAC 
TTTACTTCTC CAATAAGAAG ATATTCAGAT ATTGTAGTAC ACCGCTTGTT AATGGCAGCC 
ATTTCAAAAG ATAAGAAAAT GGAAATTAAG GGAAATCTGT TCAGCAACAA AGATCTTGAG 
GAATTATGCA GACATATCAA CAACAGAAAC CAAGCAGCAC AGCATTCTCA GAAGCAGTCT 
ACTGAGCTCT TCCAGTGCAT GTACTTCAAA GACAAAGACC CTGCCACCGA GGAGCGTTGC 
ATATCTGACG GAGTTATTTA TTCAATTAGA ACAAATGGTG TGCTTCTATT TATACCAAGG 
TTTGGGATTA AAGGTGCTGC TTATCTAAAA AATAAAGATG GTTTAGTCAT CTCATGTGGC 
CCAGATAGCT GTTCTGAATG GAAACCAGGA TCCCTTCAAC GATTTCAAAA CAAAATTACC 
TCTACTACAA CAGATGGGGA ATCTGTTACG TTCCATTTGT TTGACCATGT AACCGTAAGA 
ATATCCATAC AGGCCTCACG TTGCCATTCT GATACAATCA GACTTGAAAT AATTAGTAAC 
AAACCATACA AGATACCAAA TACAGAACTT ATTCATCAGA GTTCCCCCTT GCTGAAGAGT 
GAGTTAGTGA AAGAAGTAAC TAAATCTGTG GAAGAAGCTC AGCTTGCCCA AGAAGTCAAA 
GTAAACATCA TTCAGGAGGA ATATCAAGAA TATCGCCAAA CAAAGGGAAG GAGCCTATAC 
ACACTTCTAG AGGAGATACG GGACCTAGCT CTCCTGGATG TTTCAAACAA TTATGGAATA 
TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

DIS3L ( NM_001323946.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_001310875.1 Homo sapiens DIS3 like exosome 3'-5' exoribonuclease (DIS3L), transcript variant 12, mRNA.

Price & Availability↑

CloneID	OHu82920
Clone ID Related Accession (Same CDS sequence)	NM_001323941.2 , NM_001323938.2 , NM_001323946.1 , NM_001323939.1 , NM_001323939.2 , NM_001323938.1 , NM_001323946.2 , NM_001323941.1
Accession Version	NM_001323946.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2763bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-09-27
Organism	Homo sapiens(human)
Product	DIS3-like exonuclease 1 isoform 3
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AC055855.9. On May 31, 2019 this sequence version replaced NM_001323946.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. ##Evidence-Data-START## Transcript exon combination :: SRR1803614.58121.1, SRR1803614.213107.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1968540 [ECO:0000348] ##Evidence-Data-END##

ATGGAGAAGT GGCAGACCAG GAGCATATAC AACGCAGCTG TTTGGTACTA TCATCACTGC 
CAGGACAGGA TGCCAATTGT TATGGTGACA GAAGATGAAG AGGCAATTCA GCAGTATGGA 
AGTGAAACAG AAGGAGTATT CGTGATTACT TTCAAGAATT ACCTGGACAA TTTCTGGCCT 
GATTTAAAAG CTGCCCACGA GCTTTGTGAT TCTATCCTTC AGTCTCGACG GGAGAGAGAG 
AATGAGAGTC AGGAGAGCCA TGGGAAGGAG TACCCAGAAC ATCTTCCCCT GGAAGTGTTA 
GAAGCTGGGA TTAAATCTGG ACGCTATATC CAGGGAATTC TGAATGTCAA CAAACACAGA 
GCCCAAATAG AAGCTTTTGT TCGACTTCAA GGAGCCAGCA GTAAAGATTC AGATTTAGTC 
AGTGACATCC TAATCCACGG GATGAAGGCT CGAAACCGCT CAATTCATGG AGATGTGGTA 
GTTGTGGAGC TGCTTCCTAA AAATGAATGG AAAGGAAGAA CCGTAGCCCT GTGTGAGAAT 
GACTGTGACG ACAAGGCTTC GGGCGAGTCC CCAAGTGAGC CCATGCCTAC AGGTCGAGTG 
GTGGGCATAC TTCAGAAGAA CTGGCGGGAT TATGTGGTGA CATTTCCGTC CAAAGAAGAG 
GTCCAATCTC AGGGCAAAAA TGCTCAGAAA ATCCTGGTTA CACCTTGGGA TTACAGAATT 
CCCAAAATTC GAATTAGCAC TCAGCAAGCA GAAACCCTCC AGGACTTCAG GGTGGTCGTG 
CGCATCGATT CCTGGGAGTC AACATCTGTG TATCCAAATG GACATTTTGT GCGTGTTTTA 
GGAAGAATCG GAGATCTGGA AGGGGAAATT GCAACCATCC TGGTGGAAAA CAGTATTTCA 
GTTATTCCTT TCTCAGAAGC TCAGATGTGT GAGATGCCAG TAAACACACC AGAAAGTCCC 
TGGAAGGTGA GTCCTGAAGA GGAACAAAAA CGTAAAGACT TGAGGAAAAG CCATCTCGTA 
TTCAGCATTG ACCCCAAAGG TTGTGAAGAT GTGGATGACA CACTCTCAGT CAGAACCTTA 
AATAATGGCA ACCTGGAACT TGGGGTCCAC ATCGCAGATG TAACACACTT TGTGGCACCA 
AATTCTTACA TTGATATTGA AGCTAGAACA AGGGCCACCA CTTATTATCT AGCAGATCGT 
CGCTATGACA TGCTGCCTTC CGTCCTCAGT GCAGATTTGT GTTCCCTTCT GGGAGGCGTT 
GATAGGTATG CTGTAAGCAT CATGTGGGAA CTGGATAAAG CCTCTTATGA AATTAAGAAA 
GTGTGGTATG GCAGAACCAT TATTCGATCA GCATACAAAC TGTTCTATGA AGCAGCCCAA 
GAACTACTGG ATGGAAACTT AAGCGTTGTT GATGATATTC CAGAATTCAA AGACTTGGAT 
GAGAAGAGCA GACAAGCCAA GCTGGAGGAG TTGGTGTGGG CAATTGGAAA GCTGACCGAC 
ATAGCTCGCC ATGTCAGAGC TAAACGAGAC GGATGTGGTG CCCTGGAACT GGAAGGGGTA 
GAGGTTTGCG TACAGCTAGA TGACAAAAAG AACATTCACG ACCTCATCCC CAAGCAGCCC 
CTGGAAGTCC ACGAGACAGT GGCTGAATGC ATGATCCTGG CCAACCACTG GGTCGCCAAA 
AAGATCTGGG AGAGCTTCCC TCATCAGGCC TTGCTGCGCC AGCACCCTCC TCCACACCAG 
GAGTTCTTTT CAGAACTCCG GGAATGTGCT AAAGCCAAAG GCTTCTTCAT AGATACACGG 
TCCAATAAAA CACTGGCTGA TTCTCTGGAT AATGCGAACG ACCCCCACGA TCCCATTGTG 
AACAGGCTAC TGCGCTCCAT GGCCACGCAG GCCATGTCGA ATGCTCTGTA CTTCTCCACC 
GGATCCTGTG CGGAGGAGGA GTTCCATCAT TACGGTCTTG CATTAGATAA ATATACCCAC 
TTTACTTCTC CAATAAGAAG ATATTCAGAT ATTGTAGTAC ACCGCTTGTT AATGGCAGCC 
ATTTCAAAAG ATAAGAAAAT GGAAATTAAG GGAAATCTGT TCAGCAACAA AGATCTTGAG 
GAATTATGCA GACATATCAA CAACAGAAAC CAAGCAGCAC AGCATTCTCA GAAGCAGTCT 
ACTGAGCTCT TCCAGTGCAT GTACTTCAAA GACAAAGACC CTGCCACCGA GGAGCGTTGC 
ATATCTGACG GAGTTATTTA TTCAATTAGA ACAAATGGTG TGCTTCTATT TATACCAAGG 
TTTGGGATTA AAGGTGCTGC TTATCTAAAA AATAAAGATG GTTTAGTCAT CTCATGTGGC 
CCAGATAGCT GTTCTGAATG GAAACCAGGA TCCCTTCAAC GATTTCAAAA CAAAATTACC 
TCTACTACAA CAGATGGGGA ATCTGTTACG TTCCATTTGT TTGACCATGT AACCGTAAGA 
ATATCCATAC AGGCCTCACG TTGCCATTCT GATACAATCA GACTTGAAAT AATTAGTAAC 
AAACCATACA AGATACCAAA TACAGAACTT ATTCATCAGA GTTCCCCCTT GCTGAAGAGT 
GAGTTAGTGA AAGAAGTAAC TAAATCTGTG GAAGAAGCTC AGCTTGCCCA AGAAGTCAAA 
GTAAACATCA TTCAGGAGGA ATATCAAGAA TATCGCCAAA CAAAGGGAAG GAGCCTATAC 
ACACTTCTAG AGGAGATACG GGACCTAGCT CTCCTGGATG TTTCAAACAA TTATGGAATA 
TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001310875.1
CDS	551..3313
Translation	MEKWQTRSIYNAAVWYYHHCQDRMPIVMVTEDEEAIQQYGSETEGVFVITFKNYLDNFWPDLKAAHELCDSILQSRRERENESQESHGKEYPEHLPLEVLEAGIKSGRYIQGILNVNKHRAQIEAFVRLQGASSKDSDLVSDILIHGMKARNRSIHGDVVVVELLPKNEWKGRTVALCENDCDDKASGESPSEPMPTGRVVGILQKNWRDYVVTFPSKEEVQSQGKNAQKILVTPWDYRIPKIRISTQQAETLQDFRVVVRIDSWESTSVYPNGHFVRVLGRIGDLEGEIATILVENSISVIPFSEAQMCEMPVNTPESPWKVSPEEEQKRKDLRKSHLVFSIDPKGCEDVDDTLSVRTLNNGNLELGVHIADVTHFVAPNSYIDIEARTRATTYYLADRRYDMLPSVLSADLCSLLGGVDRYAVSIMWELDKASYEIKKVWYGRTIIRSAYKLFYEAAQELLDGNLSVVDDIPEFKDLDEKSRQAKLEELVWAIGKLTDIARHVRAKRDGCGALELEGVEVCVQLDDKKNIHDLIPKQPLEVHETVAECMILANHWVAKKIWESFPHQALLRQHPPPHQEFFSELRECAKAKGFFIDTRSNKTLADSLDNANDPHDPIVNRLLRSMATQAMSNALYFSTGSCAEEEFHHYGLALDKYTHFTSPIRRYSDIVVHRLLMAAISKDKKMEIKGNLFSNKDLEELCRHINNRNQAAQHSQKQSTELFQCMYFKDKDPATEERCISDGVIYSIRTNGVLLFIPRFGIKGAAYLKNKDGLVISCGPDSCSEWKPGSLQRFQNKITSTTTDGESVTFHLFDHVTVRISIQASRCHSDTIRLEIISNKPYKIPNTELIHQSSPLLKSELVKEVTKSVEEAQLAQEVKVNIIQEEYQEYRQTKGRSLYTLLEEIRDLALLDVSNNYGI

Target ORF information:

RefSeq Version	NM_001323946.2
Organism	Homo sapiens(human)
Definition	Homo sapiens DIS3 like exosome 3'-5' exoribonuclease (DIS3L), transcript variant 12, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001323946.2

ORF Insert Sequence:

ATGGAGAAGT GGCAGACCAG GAGCATATAC AACGCAGCTG TTTGGTACTA TCATCACTGC 
CAGGACAGGA TGCCAATTGT TATGGTGACA GAAGATGAAG AGGCAATTCA GCAGTATGGA 
AGTGAAACAG AAGGAGTATT CGTGATTACT TTCAAGAATT ACCTGGACAA TTTCTGGCCT 
GATTTAAAAG CTGCCCACGA GCTTTGTGAT TCTATCCTTC AGTCTCGACG GGAGAGAGAG 
AATGAGAGTC AGGAGAGCCA TGGGAAGGAG TACCCAGAAC ATCTTCCCCT GGAAGTGTTA 
GAAGCTGGGA TTAAATCTGG ACGCTATATC CAGGGAATTC TGAATGTCAA CAAACACAGA 
GCCCAAATAG AAGCTTTTGT TCGACTTCAA GGAGCCAGCA GTAAAGATTC AGATTTAGTC 
AGTGACATCC TAATCCACGG GATGAAGGCT CGAAACCGCT CAATTCATGG AGATGTGGTA 
GTTGTGGAGC TGCTTCCTAA AAATGAATGG AAAGGAAGAA CCGTAGCCCT GTGTGAGAAT 
GACTGTGACG ACAAGGCTTC GGGCGAGTCC CCAAGTGAGC CCATGCCTAC AGGTCGAGTG 
GTGGGCATAC TTCAGAAGAA CTGGCGGGAT TATGTGGTGA CATTTCCGTC CAAAGAAGAG 
GTCCAATCTC AGGGCAAAAA TGCTCAGAAA ATCCTGGTTA CACCTTGGGA TTACAGAATT 
CCCAAAATTC GAATTAGCAC TCAGCAAGCA GAAACCCTCC AGGACTTCAG GGTGGTCGTG 
CGCATCGATT CCTGGGAGTC AACATCTGTG TATCCAAATG GACATTTTGT GCGTGTTTTA 
GGAAGAATCG GAGATCTGGA AGGGGAAATT GCAACCATCC TGGTGGAAAA CAGTATTTCA 
GTTATTCCTT TCTCAGAAGC TCAGATGTGT GAGATGCCAG TAAACACACC AGAAAGTCCC 
TGGAAGGTGA GTCCTGAAGA GGAACAAAAA CGTAAAGACT TGAGGAAAAG CCATCTCGTA 
TTCAGCATTG ACCCCAAAGG TTGTGAAGAT GTGGATGACA CACTCTCAGT CAGAACCTTA 
AATAATGGCA ACCTGGAACT TGGGGTCCAC ATCGCAGATG TAACACACTT TGTGGCACCA 
AATTCTTACA TTGATATTGA AGCTAGAACA AGGGCCACCA CTTATTATCT AGCAGATCGT 
CGCTATGACA TGCTGCCTTC CGTCCTCAGT GCAGATTTGT GTTCCCTTCT GGGAGGCGTT 
GATAGGTATG CTGTAAGCAT CATGTGGGAA CTGGATAAAG CCTCTTATGA AATTAAGAAA 
GTGTGGTATG GCAGAACCAT TATTCGATCA GCATACAAAC TGTTCTATGA AGCAGCCCAA 
GAACTACTGG ATGGAAACTT AAGCGTTGTT GATGATATTC CAGAATTCAA AGACTTGGAT 
GAGAAGAGCA GACAAGCCAA GCTGGAGGAG TTGGTGTGGG CAATTGGAAA GCTGACCGAC 
ATAGCTCGCC ATGTCAGAGC TAAACGAGAC GGATGTGGTG CCCTGGAACT GGAAGGGGTA 
GAGGTTTGCG TACAGCTAGA TGACAAAAAG AACATTCACG ACCTCATCCC CAAGCAGCCC 
CTGGAAGTCC ACGAGACAGT GGCTGAATGC ATGATCCTGG CCAACCACTG GGTCGCCAAA 
AAGATCTGGG AGAGCTTCCC TCATCAGGCC TTGCTGCGCC AGCACCCTCC TCCACACCAG 
GAGTTCTTTT CAGAACTCCG GGAATGTGCT AAAGCCAAAG GCTTCTTCAT AGATACACGG 
TCCAATAAAA CACTGGCTGA TTCTCTGGAT AATGCGAACG ACCCCCACGA TCCCATTGTG 
AACAGGCTAC TGCGCTCCAT GGCCACGCAG GCCATGTCGA ATGCTCTGTA CTTCTCCACC 
GGATCCTGTG CGGAGGAGGA GTTCCATCAT TACGGTCTTG CATTAGATAA ATATACCCAC 
TTTACTTCTC CAATAAGAAG ATATTCAGAT ATTGTAGTAC ACCGCTTGTT AATGGCAGCC 
ATTTCAAAAG ATAAGAAAAT GGAAATTAAG GGAAATCTGT TCAGCAACAA AGATCTTGAG 
GAATTATGCA GACATATCAA CAACAGAAAC CAAGCAGCAC AGCATTCTCA GAAGCAGTCT 
ACTGAGCTCT TCCAGTGCAT GTACTTCAAA GACAAAGACC CTGCCACCGA GGAGCGTTGC 
ATATCTGACG GAGTTATTTA TTCAATTAGA ACAAATGGTG TGCTTCTATT TATACCAAGG 
TTTGGGATTA AAGGTGCTGC TTATCTAAAA AATAAAGATG GTTTAGTCAT CTCATGTGGC 
CCAGATAGCT GTTCTGAATG GAAACCAGGA TCCCTTCAAC GATTTCAAAA CAAAATTACC 
TCTACTACAA CAGATGGGGA ATCTGTTACG TTCCATTTGT TTGACCATGT AACCGTAAGA 
ATATCCATAC AGGCCTCACG TTGCCATTCT GATACAATCA GACTTGAAAT AATTAGTAAC 
AAACCATACA AGATACCAAA TACAGAACTT ATTCATCAGA GTTCCCCCTT GCTGAAGAGT 
GAGTTAGTGA AAGAAGTAAC TAAATCTGTG GAAGAAGCTC AGCTTGCCCA AGAAGTCAAA 
GTAAACATCA TTCAGGAGGA ATATCAAGAA TATCGCCAAA CAAAGGGAAG GAGCCTATAC 
ACACTTCTAG AGGAGATACG GGACCTAGCT CTCCTGGATG TTTCAAACAA TTATGGAATA 
TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

DIS3L ( NM_001323941.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001310870.1 Homo sapiens DIS3 like exosome 3'-5' exoribonuclease (DIS3L), transcript variant 8, mRNA.

Price & Availability↑

CloneID	OHu82920
Clone ID Related Accession (Same CDS sequence)	NM_001323941.2 , NM_001323938.2 , NM_001323946.1 , NM_001323939.1 , NM_001323939.2 , NM_001323938.1 , NM_001323946.2 , NM_001323941.1
Accession Version	NM_001323941.1	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2763bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2018-12-04
Organism	Homo sapiens(human)
Product	DIS3-like exonuclease 1 isoform 3
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AC055855.9. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. ##Evidence-Data-START## Transcript exon combination :: SRR1803614.28200.1, SRR1803611.181681.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968968, SAMEA2144120 [ECO:0000348] ##Evidence-Data-END##

ATGGAGAAGT GGCAGACCAG GAGCATATAC AACGCAGCTG TTTGGTACTA TCATCACTGC 
CAGGACAGGA TGCCAATTGT TATGGTGACA GAAGATGAAG AGGCAATTCA GCAGTATGGA 
AGTGAAACAG AAGGAGTATT CGTGATTACT TTCAAGAATT ACCTGGACAA TTTCTGGCCT 
GATTTAAAAG CTGCCCACGA GCTTTGTGAT TCTATCCTTC AGTCTCGACG GGAGAGAGAG 
AATGAGAGTC AGGAGAGCCA TGGGAAGGAG TACCCAGAAC ATCTTCCCCT GGAAGTGTTA 
GAAGCTGGGA TTAAATCTGG ACGCTATATC CAGGGAATTC TGAATGTCAA CAAACACAGA 
GCCCAAATAG AAGCTTTTGT TCGACTTCAA GGAGCCAGCA GTAAAGATTC AGATTTAGTC 
AGTGACATCC TAATCCACGG GATGAAGGCT CGAAACCGCT CAATTCATGG AGATGTGGTA 
GTTGTGGAGC TGCTTCCTAA AAATGAATGG AAAGGAAGAA CCGTAGCCCT GTGTGAGAAT 
GACTGTGACG ACAAGGCTTC GGGCGAGTCC CCAAGTGAGC CCATGCCTAC AGGTCGAGTG 
GTGGGCATAC TTCAGAAGAA CTGGCGGGAT TATGTGGTGA CATTTCCGTC CAAAGAAGAG 
GTCCAATCTC AGGGCAAAAA TGCTCAGAAA ATCCTGGTTA CACCTTGGGA TTACAGAATT 
CCCAAAATTC GAATTAGCAC TCAGCAAGCA GAAACCCTCC AGGACTTCAG GGTGGTCGTG 
CGCATCGATT CCTGGGAGTC AACATCTGTG TATCCAAATG GACATTTTGT GCGTGTTTTA 
GGAAGAATCG GAGATCTGGA AGGGGAAATT GCAACCATCC TGGTGGAAAA CAGTATTTCA 
GTTATTCCTT TCTCAGAAGC TCAGATGTGT GAGATGCCAG TAAACACACC AGAAAGTCCC 
TGGAAGGTGA GTCCTGAAGA GGAACAAAAA CGTAAAGACT TGAGGAAAAG CCATCTCGTA 
TTCAGCATTG ACCCCAAAGG TTGTGAAGAT GTGGATGACA CACTCTCAGT CAGAACCTTA 
AATAATGGCA ACCTGGAACT TGGGGTCCAC ATCGCAGATG TAACACACTT TGTGGCACCA 
AATTCTTACA TTGATATTGA AGCTAGAACA AGGGCCACCA CTTATTATCT AGCAGATCGT 
CGCTATGACA TGCTGCCTTC CGTCCTCAGT GCAGATTTGT GTTCCCTTCT GGGAGGCGTT 
GATAGGTATG CTGTAAGCAT CATGTGGGAA CTGGATAAAG CCTCTTATGA AATTAAGAAA 
GTGTGGTATG GCAGAACCAT TATTCGATCA GCATACAAAC TGTTCTATGA AGCAGCCCAA 
GAACTACTGG ATGGAAACTT AAGCGTTGTT GATGATATTC CAGAATTCAA AGACTTGGAT 
GAGAAGAGCA GACAAGCCAA GCTGGAGGAG TTGGTGTGGG CAATTGGAAA GCTGACCGAC 
ATAGCTCGCC ATGTCAGAGC TAAACGAGAC GGATGTGGTG CCCTGGAACT GGAAGGGGTA 
GAGGTTTGCG TACAGCTAGA TGACAAAAAG AACATTCACG ACCTCATCCC CAAGCAGCCC 
CTGGAAGTCC ACGAGACAGT GGCTGAATGC ATGATCCTGG CCAACCACTG GGTCGCCAAA 
AAGATCTGGG AGAGCTTCCC TCATCAGGCC TTGCTGCGCC AGCACCCTCC TCCACACCAG 
GAGTTCTTTT CAGAACTCCG GGAATGTGCT AAAGCCAAAG GCTTCTTCAT AGATACACGG 
TCCAATAAAA CACTGGCTGA TTCTCTGGAT AATGCGAACG ACCCCCACGA TCCCATTGTG 
AACAGGCTAC TGCGCTCCAT GGCCACGCAG GCCATGTCGA ATGCTCTGTA CTTCTCCACC 
GGATCCTGTG CGGAGGAGGA GTTCCATCAT TACGGTCTTG CATTAGATAA ATATACCCAC 
TTTACTTCTC CAATAAGAAG ATATTCAGAT ATTGTAGTAC ACCGCTTGTT AATGGCAGCC 
ATTTCAAAAG ATAAGAAAAT GGAAATTAAG GGAAATCTGT TCAGCAACAA AGATCTTGAG 
GAATTATGCA GACATATCAA CAACAGAAAC CAAGCAGCAC AGCATTCTCA GAAGCAGTCT 
ACTGAGCTCT TCCAGTGCAT GTACTTCAAA GACAAAGACC CTGCCACCGA GGAGCGTTGC 
ATATCTGACG GAGTTATTTA TTCAATTAGA ACAAATGGTG TGCTTCTATT TATACCAAGG 
TTTGGGATTA AAGGTGCTGC TTATCTAAAA AATAAAGATG GTTTAGTCAT CTCATGTGGC 
CCAGATAGCT GTTCTGAATG GAAACCAGGA TCCCTTCAAC GATTTCAAAA CAAAATTACC 
TCTACTACAA CAGATGGGGA ATCTGTTACG TTCCATTTGT TTGACCATGT AACCGTAAGA 
ATATCCATAC AGGCCTCACG TTGCCATTCT GATACAATCA GACTTGAAAT AATTAGTAAC 
AAACCATACA AGATACCAAA TACAGAACTT ATTCATCAGA GTTCCCCCTT GCTGAAGAGT 
GAGTTAGTGA AAGAAGTAAC TAAATCTGTG GAAGAAGCTC AGCTTGCCCA AGAAGTCAAA 
GTAAACATCA TTCAGGAGGA ATATCAAGAA TATCGCCAAA CAAAGGGAAG GAGCCTATAC 
ACACTTCTAG AGGAGATACG GGACCTAGCT CTCCTGGATG TTTCAAACAA TTATGGAATA 
TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001310870.1
CDS	820..3582
Translation	MEKWQTRSIYNAAVWYYHHCQDRMPIVMVTEDEEAIQQYGSETEGVFVITFKNYLDNFWPDLKAAHELCDSILQSRRERENESQESHGKEYPEHLPLEVLEAGIKSGRYIQGILNVNKHRAQIEAFVRLQGASSKDSDLVSDILIHGMKARNRSIHGDVVVVELLPKNEWKGRTVALCENDCDDKASGESPSEPMPTGRVVGILQKNWRDYVVTFPSKEEVQSQGKNAQKILVTPWDYRIPKIRISTQQAETLQDFRVVVRIDSWESTSVYPNGHFVRVLGRIGDLEGEIATILVENSISVIPFSEAQMCEMPVNTPESPWKVSPEEEQKRKDLRKSHLVFSIDPKGCEDVDDTLSVRTLNNGNLELGVHIADVTHFVAPNSYIDIEARTRATTYYLADRRYDMLPSVLSADLCSLLGGVDRYAVSIMWELDKASYEIKKVWYGRTIIRSAYKLFYEAAQELLDGNLSVVDDIPEFKDLDEKSRQAKLEELVWAIGKLTDIARHVRAKRDGCGALELEGVEVCVQLDDKKNIHDLIPKQPLEVHETVAECMILANHWVAKKIWESFPHQALLRQHPPPHQEFFSELRECAKAKGFFIDTRSNKTLADSLDNANDPHDPIVNRLLRSMATQAMSNALYFSTGSCAEEEFHHYGLALDKYTHFTSPIRRYSDIVVHRLLMAAISKDKKMEIKGNLFSNKDLEELCRHINNRNQAAQHSQKQSTELFQCMYFKDKDPATEERCISDGVIYSIRTNGVLLFIPRFGIKGAAYLKNKDGLVISCGPDSCSEWKPGSLQRFQNKITSTTTDGESVTFHLFDHVTVRISIQASRCHSDTIRLEIISNKPYKIPNTELIHQSSPLLKSELVKEVTKSVEEAQLAQEVKVNIIQEEYQEYRQTKGRSLYTLLEEIRDLALLDVSNNYGI

Target ORF information:

RefSeq Version	NM_001323941.1
Organism	Homo sapiens(human)
Definition	Homo sapiens DIS3 like exosome 3'-5' exoribonuclease (DIS3L), transcript variant 8, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001323941.1

ORF Insert Sequence:

ATGGAGAAGT GGCAGACCAG GAGCATATAC AACGCAGCTG TTTGGTACTA TCATCACTGC 
CAGGACAGGA TGCCAATTGT TATGGTGACA GAAGATGAAG AGGCAATTCA GCAGTATGGA 
AGTGAAACAG AAGGAGTATT CGTGATTACT TTCAAGAATT ACCTGGACAA TTTCTGGCCT 
GATTTAAAAG CTGCCCACGA GCTTTGTGAT TCTATCCTTC AGTCTCGACG GGAGAGAGAG 
AATGAGAGTC AGGAGAGCCA TGGGAAGGAG TACCCAGAAC ATCTTCCCCT GGAAGTGTTA 
GAAGCTGGGA TTAAATCTGG ACGCTATATC CAGGGAATTC TGAATGTCAA CAAACACAGA 
GCCCAAATAG AAGCTTTTGT TCGACTTCAA GGAGCCAGCA GTAAAGATTC AGATTTAGTC 
AGTGACATCC TAATCCACGG GATGAAGGCT CGAAACCGCT CAATTCATGG AGATGTGGTA 
GTTGTGGAGC TGCTTCCTAA AAATGAATGG AAAGGAAGAA CCGTAGCCCT GTGTGAGAAT 
GACTGTGACG ACAAGGCTTC GGGCGAGTCC CCAAGTGAGC CCATGCCTAC AGGTCGAGTG 
GTGGGCATAC TTCAGAAGAA CTGGCGGGAT TATGTGGTGA CATTTCCGTC CAAAGAAGAG 
GTCCAATCTC AGGGCAAAAA TGCTCAGAAA ATCCTGGTTA CACCTTGGGA TTACAGAATT 
CCCAAAATTC GAATTAGCAC TCAGCAAGCA GAAACCCTCC AGGACTTCAG GGTGGTCGTG 
CGCATCGATT CCTGGGAGTC AACATCTGTG TATCCAAATG GACATTTTGT GCGTGTTTTA 
GGAAGAATCG GAGATCTGGA AGGGGAAATT GCAACCATCC TGGTGGAAAA CAGTATTTCA 
GTTATTCCTT TCTCAGAAGC TCAGATGTGT GAGATGCCAG TAAACACACC AGAAAGTCCC 
TGGAAGGTGA GTCCTGAAGA GGAACAAAAA CGTAAAGACT TGAGGAAAAG CCATCTCGTA 
TTCAGCATTG ACCCCAAAGG TTGTGAAGAT GTGGATGACA CACTCTCAGT CAGAACCTTA 
AATAATGGCA ACCTGGAACT TGGGGTCCAC ATCGCAGATG TAACACACTT TGTGGCACCA 
AATTCTTACA TTGATATTGA AGCTAGAACA AGGGCCACCA CTTATTATCT AGCAGATCGT 
CGCTATGACA TGCTGCCTTC CGTCCTCAGT GCAGATTTGT GTTCCCTTCT GGGAGGCGTT 
GATAGGTATG CTGTAAGCAT CATGTGGGAA CTGGATAAAG CCTCTTATGA AATTAAGAAA 
GTGTGGTATG GCAGAACCAT TATTCGATCA GCATACAAAC TGTTCTATGA AGCAGCCCAA 
GAACTACTGG ATGGAAACTT AAGCGTTGTT GATGATATTC CAGAATTCAA AGACTTGGAT 
GAGAAGAGCA GACAAGCCAA GCTGGAGGAG TTGGTGTGGG CAATTGGAAA GCTGACCGAC 
ATAGCTCGCC ATGTCAGAGC TAAACGAGAC GGATGTGGTG CCCTGGAACT GGAAGGGGTA 
GAGGTTTGCG TACAGCTAGA TGACAAAAAG AACATTCACG ACCTCATCCC CAAGCAGCCC 
CTGGAAGTCC ACGAGACAGT GGCTGAATGC ATGATCCTGG CCAACCACTG GGTCGCCAAA 
AAGATCTGGG AGAGCTTCCC TCATCAGGCC TTGCTGCGCC AGCACCCTCC TCCACACCAG 
GAGTTCTTTT CAGAACTCCG GGAATGTGCT AAAGCCAAAG GCTTCTTCAT AGATACACGG 
TCCAATAAAA CACTGGCTGA TTCTCTGGAT AATGCGAACG ACCCCCACGA TCCCATTGTG 
AACAGGCTAC TGCGCTCCAT GGCCACGCAG GCCATGTCGA ATGCTCTGTA CTTCTCCACC 
GGATCCTGTG CGGAGGAGGA GTTCCATCAT TACGGTCTTG CATTAGATAA ATATACCCAC 
TTTACTTCTC CAATAAGAAG ATATTCAGAT ATTGTAGTAC ACCGCTTGTT AATGGCAGCC 
ATTTCAAAAG ATAAGAAAAT GGAAATTAAG GGAAATCTGT TCAGCAACAA AGATCTTGAG 
GAATTATGCA GACATATCAA CAACAGAAAC CAAGCAGCAC AGCATTCTCA GAAGCAGTCT 
ACTGAGCTCT TCCAGTGCAT GTACTTCAAA GACAAAGACC CTGCCACCGA GGAGCGTTGC 
ATATCTGACG GAGTTATTTA TTCAATTAGA ACAAATGGTG TGCTTCTATT TATACCAAGG 
TTTGGGATTA AAGGTGCTGC TTATCTAAAA AATAAAGATG GTTTAGTCAT CTCATGTGGC 
CCAGATAGCT GTTCTGAATG GAAACCAGGA TCCCTTCAAC GATTTCAAAA CAAAATTACC 
TCTACTACAA CAGATGGGGA ATCTGTTACG TTCCATTTGT TTGACCATGT AACCGTAAGA 
ATATCCATAC AGGCCTCACG TTGCCATTCT GATACAATCA GACTTGAAAT AATTAGTAAC 
AAACCATACA AGATACCAAA TACAGAACTT ATTCATCAGA GTTCCCCCTT GCTGAAGAGT 
GAGTTAGTGA AAGAAGTAAC TAAATCTGTG GAAGAAGCTC AGCTTGCCCA AGAAGTCAAA 
GTAAACATCA TTCAGGAGGA ATATCAAGAA TATCGCCAAA CAAAGGGAAG GAGCCTATAC 
ACACTTCTAG AGGAGATACG GGACCTAGCT CTCCTGGATG TTTCAAACAA TTATGGAATA 
TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

DIS3L ( XM_005254146.4 ) cDNA ORF clone, Homo sapiens(human) -> XP_005254203.1 Homo sapiens DIS3 like exosome 3'-5' exoribonuclease (DIS3L), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OHu48095
Clone ID Related Accession (Same CDS sequence)	XM_005254146.4 , XM_005254146.3
Accession Version	XM_005254146.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2547bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	DIS3-like exonuclease 1 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000015.10) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Mar 26, 2018 this sequence version replaced XM_005254146.3. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGCTGCAGA AGCGGGAGAA GGTGCTGCTG CTGAGGACCT TCCAGGGCCG CACGCTGCGG 
ATCGTGCGCG AGCACTACCT GCGGCCCTGC GTGCCCTGCC ACAGCCCGCT CTGCCCGCAG 
CCCGCCGCCT GCAGCCACGA TGGGAAACTC TTGTCTAGTG ATGTGACTCA TTACGTGATC 
CCAGACTGGA AAGTTGTTCA AGATTATCTT GAGATCCTTG AGTTTCCTGA GTTGAAGGGA 
ATTATTTTCA TGCAGACAGC TTGTCAAGCT GTGCAGCATC AAAGAGGCAG GAGACAGTAT 
AACAAACTGC GAAACCTGCT GAAGGATGCG CGTCATGATT GCATTCTCTT TGCTAATGAA 
TTCCAGCAAT GCTGCTATCT GCCACGGGAA AGAGGAGAGT CCATGGAGAA GTGGCAGACC 
AGGAGCATAT ACAACGCAGC TGTTTGGTAC TATCATCACT GCCAGGACAG GATGCCAATT 
GTTATGGTGA CAGAAGATGA AGAGGCAATT CAGCAGTATG GAAGTGAAAC AGAAGGAGTA 
TTCGTGATTA CTTTCAAGAA TTACCTGGAC AATTTCTGGC CTGATTTAAA AGCTGCCCAC 
GAGCTTTGTG ATTCTATCCT TCAGTCTCGA CGGGAGAGAG AGAATGAGAG TCAGGAGAGC 
CATGGGAAGG AGTACCCAGA ACATCTTCCC CTGGAAGTGT TAGAAGCTGG GATTAAATCT 
GGACGCTATA TCCAGGGAAT TCTGAATGTC AACAAACACA GAGCCCAAAT AGAAGCTTTT 
GTTCGACTTC AAGGAGCCAG CAGTAAAGAT TCAGATTTAG TCAGTGACAT CCTAATCCAC 
GGGATGAAGG CTCGAAACCG CTCAATTCAT GGAGATGTGG TAGTTGTGGA GCTGCTTCCT 
AAAAATGAAT GGAAAGGAAG AACCGTAGCC CTGTGTGAGA ATGACTGTGA CGACAAGGCT 
TCGGGCGAGT CCCCAAGTGA GCCCATGCCT ACAGGTCGAG TGGTGGGCAT ACTTCAGAAG 
AACTGGCGGG ATTATGTGGT GACATTTCCG TCCAAAGAAG AGGTCCAATC TCAGGGCAAA 
AATGCTCAGA AAATCCTGGT TACACCTTGG GATTACAGAA TTCCCAAAAT TCGAATTAGC 
ACTCAGCAAG CAGAAACCCT CCAGGACTTC AGGGTGGTCG TGCGCATCGA TTCCTGGGAG 
TCAACATCTG TGTATCCAAA TGGACATTTT GTGCGTGTTT TAGGAAGAAT CGGAGATCTG 
GAAGGGGAAA TTGCAACCAT CCTGGTGGAA AACAGTATTT CAGTTATTCC TTTCTCAGAA 
GCTCAGATGT GTGAGATGCC AGTAAACACA CCAGAAAGTC CCTGGAAGGT GAGTCCTGAA 
GAGGAACAAA AACGTAAAGA CTTGAGGAAA AGCCATCTCG TATTCAGCAT TGACCCCAAA 
GGTTGTGAAG ATGTGGATGA CACACTCTCA GTCAGAACCT TAAATAATGG CAACCTGGAA 
CTTGGGGTCC ACATCGCAGA TGTAACACAC TTTGTGGCAC CAAATTCTTA CATTGATATT 
GAAGCTAGAA CAAGGGCCAC CACTTATTAT CTAGCAGATC GTCGCTATGA CATGCTGCCT 
TCCGTCCTCA GTGCAGATTT GTGTTCCCTT CTGGGAGGCG TTGATAGGTA TGCTGTAAGC 
ATCATGTGGG AACTGGATAA AGCCTCTTAT GAAATTAAGA AAGTGTGGTA TGGCAGAACC 
ATTATTCGAT CAGCATACAA ACTGTTCTAT GAAGCAGCCC AAGAACTACT GGATGGAAAC 
TTAAGCGTTG TTGATGATAT TCCAGAATTC AAAGACTTGG ATGAGAAGAG CAGACAAGCC 
AAGCTGGAGG AGTTGGTGTG GGCAATTGGA AAGCTGACCG ACATAGCTCG CCATGTCAGA 
GCTAAACGAG ACGGATGTGG TGCCCTGGAA CTGGAAGGGG TAGAGGTTTG CGTACAGCTA 
GATGACAAAA AGAACATTCA CGACCTCATC CCCAAGCAGC CCCTGGAAGT CCACGAGACA 
GTGGCTGAAT GCATGATCCT GGCCAACCAC TGGGTCGCCA AAAAGATCTG GGAGAGCTTC 
CCTCATCAGG CCTTGCTGCG CCAGCACCCT CCTCCACACC AGGAGTTCTT TTCAGAACTC 
CGGGAATGTG CTAAAGCCAA AGGCTTCTTC ATAGATACAC GGTCCAATAA AACACTGGCT 
GATTCTCTGG ATAATGCGAA CGACCCCCAC GATCCCATTG TGAACAGGCT ACTGCGCTCC 
ATGGCCACGC AGGCCATGTC GAATGCTCTG TACTTCTCCA CCGGATCCTG TGCGGAGGAG 
GAGTTCCATC ATTACGGTCT TGCATTAGAT AAATATACCC ACTTTACTTC TCCAATAAGA 
AGATATTCAG ATATTGTAGT ACACCGCTTG TTAATGGCAG CCATTTCAAA AGATAAGAAA 
ATGGAAATTA AGGGAAATCT GTTCAGCAAC AAAGATCTTG AGGAATTATG CAGACATATC 
AACAACAGAA ACCAAGTGGA AATGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_005254203.1
CDS	2..2548
Translation	MLQKREKVLLLRTFQGRTLRIVREHYLRPCVPCHSPLCPQPAACSHDGKLLSSDVTHYVIPDWKVVQDYLEILEFPELKGIIFMQTACQAVQHQRGRRQYNKLRNLLKDARHDCILFANEFQQCCYLPRERGESMEKWQTRSIYNAAVWYYHHCQDRMPIVMVTEDEEAIQQYGSETEGVFVITFKNYLDNFWPDLKAAHELCDSILQSRRERENESQESHGKEYPEHLPLEVLEAGIKSGRYIQGILNVNKHRAQIEAFVRLQGASSKDSDLVSDILIHGMKARNRSIHGDVVVVELLPKNEWKGRTVALCENDCDDKASGESPSEPMPTGRVVGILQKNWRDYVVTFPSKEEVQSQGKNAQKILVTPWDYRIPKIRISTQQAETLQDFRVVVRIDSWESTSVYPNGHFVRVLGRIGDLEGEIATILVENSISVIPFSEAQMCEMPVNTPESPWKVSPEEEQKRKDLRKSHLVFSIDPKGCEDVDDTLSVRTLNNGNLELGVHIADVTHFVAPNSYIDIEARTRATTYYLADRRYDMLPSVLSADLCSLLGGVDRYAVSIMWELDKASYEIKKVWYGRTIIRSAYKLFYEAAQELLDGNLSVVDDIPEFKDLDEKSRQAKLEELVWAIGKLTDIARHVRAKRDGCGALELEGVEVCVQLDDKKNIHDLIPKQPLEVHETVAECMILANHWVAKKIWESFPHQALLRQHPPPHQEFFSELRECAKAKGFFIDTRSNKTLADSLDNANDPHDPIVNRLLRSMATQAMSNALYFSTGSCAEEEFHHYGLALDKYTHFTSPIRRYSDIVVHRLLMAAISKDKKMEIKGNLFSNKDLEELCRHINNRNQVEM

Target ORF information:

RefSeq Version	XM_005254146.4
Organism	Homo sapiens(human)
Definition	Homo sapiens DIS3 like exosome 3'-5' exoribonuclease (DIS3L), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_005254146.4

ORF Insert Sequence:

ATGCTGCAGA AGCGGGAGAA GGTGCTGCTG CTGAGGACCT TCCAGGGCCG CACGCTGCGG 
ATCGTGCGCG AGCACTACCT GCGGCCCTGC GTGCCCTGCC ACAGCCCGCT CTGCCCGCAG 
CCCGCCGCCT GCAGCCACGA TGGGAAACTC TTGTCTAGTG ATGTGACTCA TTACGTGATC 
CCAGACTGGA AAGTTGTTCA AGATTATCTT GAGATCCTTG AGTTTCCTGA GTTGAAGGGA 
ATTATTTTCA TGCAGACAGC TTGTCAAGCT GTGCAGCATC AAAGAGGCAG GAGACAGTAT 
AACAAACTGC GAAACCTGCT GAAGGATGCG CGTCATGATT GCATTCTCTT TGCTAATGAA 
TTCCAGCAAT GCTGCTATCT GCCACGGGAA AGAGGAGAGT CCATGGAGAA GTGGCAGACC 
AGGAGCATAT ACAACGCAGC TGTTTGGTAC TATCATCACT GCCAGGACAG GATGCCAATT 
GTTATGGTGA CAGAAGATGA AGAGGCAATT CAGCAGTATG GAAGTGAAAC AGAAGGAGTA 
TTCGTGATTA CTTTCAAGAA TTACCTGGAC AATTTCTGGC CTGATTTAAA AGCTGCCCAC 
GAGCTTTGTG ATTCTATCCT TCAGTCTCGA CGGGAGAGAG AGAATGAGAG TCAGGAGAGC 
CATGGGAAGG AGTACCCAGA ACATCTTCCC CTGGAAGTGT TAGAAGCTGG GATTAAATCT 
GGACGCTATA TCCAGGGAAT TCTGAATGTC AACAAACACA GAGCCCAAAT AGAAGCTTTT 
GTTCGACTTC AAGGAGCCAG CAGTAAAGAT TCAGATTTAG TCAGTGACAT CCTAATCCAC 
GGGATGAAGG CTCGAAACCG CTCAATTCAT GGAGATGTGG TAGTTGTGGA GCTGCTTCCT 
AAAAATGAAT GGAAAGGAAG AACCGTAGCC CTGTGTGAGA ATGACTGTGA CGACAAGGCT 
TCGGGCGAGT CCCCAAGTGA GCCCATGCCT ACAGGTCGAG TGGTGGGCAT ACTTCAGAAG 
AACTGGCGGG ATTATGTGGT GACATTTCCG TCCAAAGAAG AGGTCCAATC TCAGGGCAAA 
AATGCTCAGA AAATCCTGGT TACACCTTGG GATTACAGAA TTCCCAAAAT TCGAATTAGC 
ACTCAGCAAG CAGAAACCCT CCAGGACTTC AGGGTGGTCG TGCGCATCGA TTCCTGGGAG 
TCAACATCTG TGTATCCAAA TGGACATTTT GTGCGTGTTT TAGGAAGAAT CGGAGATCTG 
GAAGGGGAAA TTGCAACCAT CCTGGTGGAA AACAGTATTT CAGTTATTCC TTTCTCAGAA 
GCTCAGATGT GTGAGATGCC AGTAAACACA CCAGAAAGTC CCTGGAAGGT GAGTCCTGAA 
GAGGAACAAA AACGTAAAGA CTTGAGGAAA AGCCATCTCG TATTCAGCAT TGACCCCAAA 
GGTTGTGAAG ATGTGGATGA CACACTCTCA GTCAGAACCT TAAATAATGG CAACCTGGAA 
CTTGGGGTCC ACATCGCAGA TGTAACACAC TTTGTGGCAC CAAATTCTTA CATTGATATT 
GAAGCTAGAA CAAGGGCCAC CACTTATTAT CTAGCAGATC GTCGCTATGA CATGCTGCCT 
TCCGTCCTCA GTGCAGATTT GTGTTCCCTT CTGGGAGGCG TTGATAGGTA TGCTGTAAGC 
ATCATGTGGG AACTGGATAA AGCCTCTTAT GAAATTAAGA AAGTGTGGTA TGGCAGAACC 
ATTATTCGAT CAGCATACAA ACTGTTCTAT GAAGCAGCCC AAGAACTACT GGATGGAAAC 
TTAAGCGTTG TTGATGATAT TCCAGAATTC AAAGACTTGG ATGAGAAGAG CAGACAAGCC 
AAGCTGGAGG AGTTGGTGTG GGCAATTGGA AAGCTGACCG ACATAGCTCG CCATGTCAGA 
GCTAAACGAG ACGGATGTGG TGCCCTGGAA CTGGAAGGGG TAGAGGTTTG CGTACAGCTA 
GATGACAAAA AGAACATTCA CGACCTCATC CCCAAGCAGC CCCTGGAAGT CCACGAGACA 
GTGGCTGAAT GCATGATCCT GGCCAACCAC TGGGTCGCCA AAAAGATCTG GGAGAGCTTC 
CCTCATCAGG CCTTGCTGCG CCAGCACCCT CCTCCACACC AGGAGTTCTT TTCAGAACTC 
CGGGAATGTG CTAAAGCCAA AGGCTTCTTC ATAGATACAC GGTCCAATAA AACACTGGCT 
GATTCTCTGG ATAATGCGAA CGACCCCCAC GATCCCATTG TGAACAGGCT ACTGCGCTCC 
ATGGCCACGC AGGCCATGTC GAATGCTCTG TACTTCTCCA CCGGATCCTG TGCGGAGGAG 
GAGTTCCATC ATTACGGTCT TGCATTAGAT AAATATACCC ACTTTACTTC TCCAATAAGA 
AGATATTCAG ATATTGTAGT ACACCGCTTG TTAATGGCAG CCATTTCAAA AGATAAGAAA 
ATGGAAATTA AGGGAAATCT GTTCAGCAAC AAAGATCTTG AGGAATTATG CAGACATATC 
AACAACAGAA ACCAAGTGGA AATGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

DIS3L ( XM_005254146.3 ) cDNA ORF clone, Homo sapiens(human) -> XP_005254203.1 Homo sapiens DIS3 like exosome 3'-5' exoribonuclease (DIS3L), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OHu48095
Clone ID Related Accession (Same CDS sequence)	XM_005254146.4 , XM_005254146.3
Accession Version	XM_005254146.3	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2547bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-06-05
Organism	Homo sapiens(human)
Product	DIS3-like exonuclease 1 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000015.10) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 6, 2016 this sequence version replaced XM_005254146.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGCTGCAGA AGCGGGAGAA GGTGCTGCTG CTGAGGACCT TCCAGGGCCG CACGCTGCGG 
ATCGTGCGCG AGCACTACCT GCGGCCCTGC GTGCCCTGCC ACAGCCCGCT CTGCCCGCAG 
CCCGCCGCCT GCAGCCACGA TGGGAAACTC TTGTCTAGTG ATGTGACTCA TTACGTGATC 
CCAGACTGGA AAGTTGTTCA AGATTATCTT GAGATCCTTG AGTTTCCTGA GTTGAAGGGA 
ATTATTTTCA TGCAGACAGC TTGTCAAGCT GTGCAGCATC AAAGAGGCAG GAGACAGTAT 
AACAAACTGC GAAACCTGCT GAAGGATGCG CGTCATGATT GCATTCTCTT TGCTAATGAA 
TTCCAGCAAT GCTGCTATCT GCCACGGGAA AGAGGAGAGT CCATGGAGAA GTGGCAGACC 
AGGAGCATAT ACAACGCAGC TGTTTGGTAC TATCATCACT GCCAGGACAG GATGCCAATT 
GTTATGGTGA CAGAAGATGA AGAGGCAATT CAGCAGTATG GAAGTGAAAC AGAAGGAGTA 
TTCGTGATTA CTTTCAAGAA TTACCTGGAC AATTTCTGGC CTGATTTAAA AGCTGCCCAC 
GAGCTTTGTG ATTCTATCCT TCAGTCTCGA CGGGAGAGAG AGAATGAGAG TCAGGAGAGC 
CATGGGAAGG AGTACCCAGA ACATCTTCCC CTGGAAGTGT TAGAAGCTGG GATTAAATCT 
GGACGCTATA TCCAGGGAAT TCTGAATGTC AACAAACACA GAGCCCAAAT AGAAGCTTTT 
GTTCGACTTC AAGGAGCCAG CAGTAAAGAT TCAGATTTAG TCAGTGACAT CCTAATCCAC 
GGGATGAAGG CTCGAAACCG CTCAATTCAT GGAGATGTGG TAGTTGTGGA GCTGCTTCCT 
AAAAATGAAT GGAAAGGAAG AACCGTAGCC CTGTGTGAGA ATGACTGTGA CGACAAGGCT 
TCGGGCGAGT CCCCAAGTGA GCCCATGCCT ACAGGTCGAG TGGTGGGCAT ACTTCAGAAG 
AACTGGCGGG ATTATGTGGT GACATTTCCG TCCAAAGAAG AGGTCCAATC TCAGGGCAAA 
AATGCTCAGA AAATCCTGGT TACACCTTGG GATTACAGAA TTCCCAAAAT TCGAATTAGC 
ACTCAGCAAG CAGAAACCCT CCAGGACTTC AGGGTGGTCG TGCGCATCGA TTCCTGGGAG 
TCAACATCTG TGTATCCAAA TGGACATTTT GTGCGTGTTT TAGGAAGAAT CGGAGATCTG 
GAAGGGGAAA TTGCAACCAT CCTGGTGGAA AACAGTATTT CAGTTATTCC TTTCTCAGAA 
GCTCAGATGT GTGAGATGCC AGTAAACACA CCAGAAAGTC CCTGGAAGGT GAGTCCTGAA 
GAGGAACAAA AACGTAAAGA CTTGAGGAAA AGCCATCTCG TATTCAGCAT TGACCCCAAA 
GGTTGTGAAG ATGTGGATGA CACACTCTCA GTCAGAACCT TAAATAATGG CAACCTGGAA 
CTTGGGGTCC ACATCGCAGA TGTAACACAC TTTGTGGCAC CAAATTCTTA CATTGATATT 
GAAGCTAGAA CAAGGGCCAC CACTTATTAT CTAGCAGATC GTCGCTATGA CATGCTGCCT 
TCCGTCCTCA GTGCAGATTT GTGTTCCCTT CTGGGAGGCG TTGATAGGTA TGCTGTAAGC 
ATCATGTGGG AACTGGATAA AGCCTCTTAT GAAATTAAGA AAGTGTGGTA TGGCAGAACC 
ATTATTCGAT CAGCATACAA ACTGTTCTAT GAAGCAGCCC AAGAACTACT GGATGGAAAC 
TTAAGCGTTG TTGATGATAT TCCAGAATTC AAAGACTTGG ATGAGAAGAG CAGACAAGCC 
AAGCTGGAGG AGTTGGTGTG GGCAATTGGA AAGCTGACCG ACATAGCTCG CCATGTCAGA 
GCTAAACGAG ACGGATGTGG TGCCCTGGAA CTGGAAGGGG TAGAGGTTTG CGTACAGCTA 
GATGACAAAA AGAACATTCA CGACCTCATC CCCAAGCAGC CCCTGGAAGT CCACGAGACA 
GTGGCTGAAT GCATGATCCT GGCCAACCAC TGGGTCGCCA AAAAGATCTG GGAGAGCTTC 
CCTCATCAGG CCTTGCTGCG CCAGCACCCT CCTCCACACC AGGAGTTCTT TTCAGAACTC 
CGGGAATGTG CTAAAGCCAA AGGCTTCTTC ATAGATACAC GGTCCAATAA AACACTGGCT 
GATTCTCTGG ATAATGCGAA CGACCCCCAC GATCCCATTG TGAACAGGCT ACTGCGCTCC 
ATGGCCACGC AGGCCATGTC GAATGCTCTG TACTTCTCCA CCGGATCCTG TGCGGAGGAG 
GAGTTCCATC ATTACGGTCT TGCATTAGAT AAATATACCC ACTTTACTTC TCCAATAAGA 
AGATATTCAG ATATTGTAGT ACACCGCTTG TTAATGGCAG CCATTTCAAA AGATAAGAAA 
ATGGAAATTA AGGGAAATCT GTTCAGCAAC AAAGATCTTG AGGAATTATG CAGACATATC 
AACAACAGAA ACCAAGTGGA AATGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_005254203.1
CDS	91..2637
Translation	MLQKREKVLLLRTFQGRTLRIVREHYLRPCVPCHSPLCPQPAACSHDGKLLSSDVTHYVIPDWKVVQDYLEILEFPELKGIIFMQTACQAVQHQRGRRQYNKLRNLLKDARHDCILFANEFQQCCYLPRERGESMEKWQTRSIYNAAVWYYHHCQDRMPIVMVTEDEEAIQQYGSETEGVFVITFKNYLDNFWPDLKAAHELCDSILQSRRERENESQESHGKEYPEHLPLEVLEAGIKSGRYIQGILNVNKHRAQIEAFVRLQGASSKDSDLVSDILIHGMKARNRSIHGDVVVVELLPKNEWKGRTVALCENDCDDKASGESPSEPMPTGRVVGILQKNWRDYVVTFPSKEEVQSQGKNAQKILVTPWDYRIPKIRISTQQAETLQDFRVVVRIDSWESTSVYPNGHFVRVLGRIGDLEGEIATILVENSISVIPFSEAQMCEMPVNTPESPWKVSPEEEQKRKDLRKSHLVFSIDPKGCEDVDDTLSVRTLNNGNLELGVHIADVTHFVAPNSYIDIEARTRATTYYLADRRYDMLPSVLSADLCSLLGGVDRYAVSIMWELDKASYEIKKVWYGRTIIRSAYKLFYEAAQELLDGNLSVVDDIPEFKDLDEKSRQAKLEELVWAIGKLTDIARHVRAKRDGCGALELEGVEVCVQLDDKKNIHDLIPKQPLEVHETVAECMILANHWVAKKIWESFPHQALLRQHPPPHQEFFSELRECAKAKGFFIDTRSNKTLADSLDNANDPHDPIVNRLLRSMATQAMSNALYFSTGSCAEEEFHHYGLALDKYTHFTSPIRRYSDIVVHRLLMAAISKDKKMEIKGNLFSNKDLEELCRHINNRNQVEM

Target ORF information:

RefSeq Version	XM_005254146.3
Organism	Homo sapiens(human)
Definition	Homo sapiens DIS3 like exosome 3'-5' exoribonuclease (DIS3L), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_005254146.3

ORF Insert Sequence:

ATGCTGCAGA AGCGGGAGAA GGTGCTGCTG CTGAGGACCT TCCAGGGCCG CACGCTGCGG 
ATCGTGCGCG AGCACTACCT GCGGCCCTGC GTGCCCTGCC ACAGCCCGCT CTGCCCGCAG 
CCCGCCGCCT GCAGCCACGA TGGGAAACTC TTGTCTAGTG ATGTGACTCA TTACGTGATC 
CCAGACTGGA AAGTTGTTCA AGATTATCTT GAGATCCTTG AGTTTCCTGA GTTGAAGGGA 
ATTATTTTCA TGCAGACAGC TTGTCAAGCT GTGCAGCATC AAAGAGGCAG GAGACAGTAT 
AACAAACTGC GAAACCTGCT GAAGGATGCG CGTCATGATT GCATTCTCTT TGCTAATGAA 
TTCCAGCAAT GCTGCTATCT GCCACGGGAA AGAGGAGAGT CCATGGAGAA GTGGCAGACC 
AGGAGCATAT ACAACGCAGC TGTTTGGTAC TATCATCACT GCCAGGACAG GATGCCAATT 
GTTATGGTGA CAGAAGATGA AGAGGCAATT CAGCAGTATG GAAGTGAAAC AGAAGGAGTA 
TTCGTGATTA CTTTCAAGAA TTACCTGGAC AATTTCTGGC CTGATTTAAA AGCTGCCCAC 
GAGCTTTGTG ATTCTATCCT TCAGTCTCGA CGGGAGAGAG AGAATGAGAG TCAGGAGAGC 
CATGGGAAGG AGTACCCAGA ACATCTTCCC CTGGAAGTGT TAGAAGCTGG GATTAAATCT 
GGACGCTATA TCCAGGGAAT TCTGAATGTC AACAAACACA GAGCCCAAAT AGAAGCTTTT 
GTTCGACTTC AAGGAGCCAG CAGTAAAGAT TCAGATTTAG TCAGTGACAT CCTAATCCAC 
GGGATGAAGG CTCGAAACCG CTCAATTCAT GGAGATGTGG TAGTTGTGGA GCTGCTTCCT 
AAAAATGAAT GGAAAGGAAG AACCGTAGCC CTGTGTGAGA ATGACTGTGA CGACAAGGCT 
TCGGGCGAGT CCCCAAGTGA GCCCATGCCT ACAGGTCGAG TGGTGGGCAT ACTTCAGAAG 
AACTGGCGGG ATTATGTGGT GACATTTCCG TCCAAAGAAG AGGTCCAATC TCAGGGCAAA 
AATGCTCAGA AAATCCTGGT TACACCTTGG GATTACAGAA TTCCCAAAAT TCGAATTAGC 
ACTCAGCAAG CAGAAACCCT CCAGGACTTC AGGGTGGTCG TGCGCATCGA TTCCTGGGAG 
TCAACATCTG TGTATCCAAA TGGACATTTT GTGCGTGTTT TAGGAAGAAT CGGAGATCTG 
GAAGGGGAAA TTGCAACCAT CCTGGTGGAA AACAGTATTT CAGTTATTCC TTTCTCAGAA 
GCTCAGATGT GTGAGATGCC AGTAAACACA CCAGAAAGTC CCTGGAAGGT GAGTCCTGAA 
GAGGAACAAA AACGTAAAGA CTTGAGGAAA AGCCATCTCG TATTCAGCAT TGACCCCAAA 
GGTTGTGAAG ATGTGGATGA CACACTCTCA GTCAGAACCT TAAATAATGG CAACCTGGAA 
CTTGGGGTCC ACATCGCAGA TGTAACACAC TTTGTGGCAC CAAATTCTTA CATTGATATT 
GAAGCTAGAA CAAGGGCCAC CACTTATTAT CTAGCAGATC GTCGCTATGA CATGCTGCCT 
TCCGTCCTCA GTGCAGATTT GTGTTCCCTT CTGGGAGGCG TTGATAGGTA TGCTGTAAGC 
ATCATGTGGG AACTGGATAA AGCCTCTTAT GAAATTAAGA AAGTGTGGTA TGGCAGAACC 
ATTATTCGAT CAGCATACAA ACTGTTCTAT GAAGCAGCCC AAGAACTACT GGATGGAAAC 
TTAAGCGTTG TTGATGATAT TCCAGAATTC AAAGACTTGG ATGAGAAGAG CAGACAAGCC 
AAGCTGGAGG AGTTGGTGTG GGCAATTGGA AAGCTGACCG ACATAGCTCG CCATGTCAGA 
GCTAAACGAG ACGGATGTGG TGCCCTGGAA CTGGAAGGGG TAGAGGTTTG CGTACAGCTA 
GATGACAAAA AGAACATTCA CGACCTCATC CCCAAGCAGC CCCTGGAAGT CCACGAGACA 
GTGGCTGAAT GCATGATCCT GGCCAACCAC TGGGTCGCCA AAAAGATCTG GGAGAGCTTC 
CCTCATCAGG CCTTGCTGCG CCAGCACCCT CCTCCACACC AGGAGTTCTT TTCAGAACTC 
CGGGAATGTG CTAAAGCCAA AGGCTTCTTC ATAGATACAC GGTCCAATAA AACACTGGCT 
GATTCTCTGG ATAATGCGAA CGACCCCCAC GATCCCATTG TGAACAGGCT ACTGCGCTCC 
ATGGCCACGC AGGCCATGTC GAATGCTCTG TACTTCTCCA CCGGATCCTG TGCGGAGGAG 
GAGTTCCATC ATTACGGTCT TGCATTAGAT AAATATACCC ACTTTACTTC TCCAATAAGA 
AGATATTCAG ATATTGTAGT ACACCGCTTG TTAATGGCAG CCATTTCAAA AGATAAGAAA 
ATGGAAATTA AGGGAAATCT GTTCAGCAAC AAAGATCTTG AGGAATTATG CAGACATATC 
AACAACAGAA ACCAAGTGGA AATGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

DIS3L ( NM_001323937.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001310866.1 Homo sapiens DIS3 like exosome 3'-5' exoribonuclease (DIS3L), transcript variant 4, mRNA.

Price & Availability↑

CloneID	OHu82921
Clone ID Related Accession (Same CDS sequence)	NM_001323937.1 , NM_001323937.2
Accession Version	NM_001323937.1	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2787bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2018-12-04
Organism	Homo sapiens(human)
Product	DIS3-like exonuclease 1 isoform 5
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AC055855.9. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. ##Evidence-Data-START## Transcript exon combination :: SRR1803613.279618.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968968, SAMEA1970526 [ECO:0000348] ##Evidence-Data-END##

ATGCAGACAG CTTGTCAAGC TGTGCAGCAT CAAAGAGGCA GGAGGAGCAT ATACAACGCA 
GCTGTTTGGT ACTATCATCA CTGCCAGGAC AGGATGCCAA TTGTTATGGT GACAGAAGAT 
GAAGAGGCAA TTCAGCAGTA TGGAAGTGAA ACAGAAGGAG TATTCGTGAT TACTTTCAAG 
AATTACCTGG ACAATTTCTG GCCTGATTTA AAAGCTGCCC ACGAGCTTTG TGATTCTATC 
CTTCAGTCTC GACGGGAGAG AGAGAATGAG AGTCAGGAGA GCCATGGGAA GGAGTACCCA 
GAACATCTTC CCCTGGAAGT GTTAGAAGCT GGGATTAAAT CTGGACGCTA TATCCAGGGA 
ATTCTGAATG TCAACAAACA CAGAGCCCAA ATAGAAGCTT TTGTTCGACT TCAAGGAGCC 
AGCAGTAAAG ATTCAGATTT AGTCAGTGAC ATCCTAATCC ACGGGATGAA GGCTCGAAAC 
CGCTCAATTC ATGGAGATGT GGTAGTTGTG GAGCTGCTTC CTAAAAATGA ATGGAAAGGA 
AGAACCGTAG CCCTGTGTGA GAATGACTGT GACGACAAGG CTTCGGGCGA GTCCCCAAGT 
GAGCCCATGC CTACAGGTCG AGTGGTGGGC ATACTTCAGA AGAACTGGCG GGATTATGTG 
GTGACATTTC CGTCCAAAGA AGAGGTCCAA TCTCAGGGCA AAAATGCTCA GAAAATCCTG 
GTTACACCTT GGGATTACAG AATTCCCAAA ATTCGAATTA GCACTCAGCA AGCAGAAACC 
CTCCAGGACT TCAGGGTGGT CGTGCGCATC GATTCCTGGG AGTCAACATC TGTGTATCCA 
AATGGACATT TTGTGCGTGT TTTAGGAAGA ATCGGAGATC TGGAAGGGGA AATTGCAACC 
ATCCTGGTGG AAAACAGTAT TTCAGTTATT CCTTTCTCAG AAGCTCAGAT GTGTGAGATG 
CCAGTAAACA CACCAGAAAG TCCCTGGAAG GTGAGTCCTG AAGAGGAACA AAAACGTAAA 
GACTTGAGGA AAAGCCATCT CGTATTCAGC ATTGACCCCA AAGGTTGTGA AGATGTGGAT 
GACACACTCT CAGTCAGAAC CTTAAATAAT GGCAACCTGG AACTTGGGGT CCACATCGCA 
GATGTAACAC ACTTTGTGGC ACCAAATTCT TACATTGATA TTGAAGCTAG AACAAGGGCC 
ACCACTTATT ATCTAGCAGA TCGTCGCTAT GACATGCTGC CTTCCGTCCT CAGTGCAGAT 
TTGTGTTCCC TTCTGGGAGG CGTTGATAGG TATGCTGTAA GCATCATGTG GGAACTGGAT 
AAAGCCTCTT ATGAAATTAA GAAAGTGTGG TATGGCAGAA CCATTATTCG ATCAGCATAC 
AAACTGTTCT ATGAAGCAGC CCAAGAACTA CTGGATGGAA ACTTAAGCGT TGTTGATGAT 
ATTCCAGAAT TCAAAGACTT GGATGAGAAG AGCAGACAAG CCAAGCTGGA GGAGTTGGTG 
TGGGCAATTG GAAAGCTGAC CGACATAGCT CGCCATGTCA GAGCTAAACG AGACGGATGT 
GGTGCCCTGG AACTGGAAGG GGTAGAGGTT TGCGTACAGC TAGATGACAA AAAGAACATT 
CACGACCTCA TCCCCAAGCA GCCCCTGGAA GTCCACGAGA CAGTGGCTGA ATGCATGATC 
CTGGCCAACC ACTGGGTCGC CAAAAAGATC TGGGAGAGCT TCCCTCATCA GGCCTTGCTG 
CGCCAGCACC CTCCTCCACA CCAGGAGTTC TTTTCAGAAC TCCGGGAATG TGCTAAAGCC 
AAAGGCTTCT TCATAGATAC ACGGTCCAAT AAAACACTGG CTGATTCTCT GGATAATGCG 
AACGACCCCC ACGATCCCAT TGTGAACAGG CTACTGCGCT CCATGGCCAC GCAGGCCATG 
TCGAATGCTC TGTACTTCTC CACCGGATCC TGTGCGGAGG AGGAGTTCCA TCATTACGGT 
CTTGCATTAG ATAAATATAC CCACTTTACT TCTCCAATAA GAAGATATTC AGATATTGTA 
GTACACCGCT TGTTAATGGC AGCCATTTCA AAAGATAAGA AAATGGAAAT TAAGGGAAAT 
CTGTTCAGCA ACAAAGATCT TGAGGAATTA TGCAGACATA TCAACAACAG AAACCAAGCA 
GCACAGCATT CTCAGAAGCA GTCTACTGAG CTCTTCCAGT GCATGTACTT CAAAGACAAA 
GACCCTGCCA CCGAGGAGCG TTGCATATCT GACGGAGTTA TTTATTCAAT TAGAACAAAT 
GGTGTGCTTC TATTTATACC AAGGTTTGGG ATTAAAGGTG CTGCTTATCT AAAAAATAAA 
GATGGTTTAG TCATCTCATG TGGCCCAGAT AGCTGTTCTG AATGGAAACC AGGATCCCTT 
CAACGATTTC AAAACAAAAT TACCTCTACT ACAACAGATG GGGAATCTGT TACGTTCCAT 
TTGTTTGACC ATGTAACCGT AAGAATATCC ATACAGGCCT CACGTTGCCA TTCTGATACA 
ATCAGACTTG AAATAATTAG TAACAAACCA TACAAGATAC CAAATACAGA ACTTATTCAT 
CAGAGTTCCC CCTTGCTGAA GAGTGAGTTA GTGAAAGAAG TAACTAAATC TGTGGAAGAA 
GCTCAGCTTG CCCAAGAAGT CAAAGTAAAC ATCATTCAGG AGGAATATCA AGAATATCGC 
CAAACAAAGG GAAGGAGCCT ATACACACTT CTAGAGGAGA TACGGGACCT AGCTCTCCTG 
GATGTTTCAA ACAATTATGG AATATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001310866.1
CDS	222..3008
Translation	MQTACQAVQHQRGRRSIYNAAVWYYHHCQDRMPIVMVTEDEEAIQQYGSETEGVFVITFKNYLDNFWPDLKAAHELCDSILQSRRERENESQESHGKEYPEHLPLEVLEAGIKSGRYIQGILNVNKHRAQIEAFVRLQGASSKDSDLVSDILIHGMKARNRSIHGDVVVVELLPKNEWKGRTVALCENDCDDKASGESPSEPMPTGRVVGILQKNWRDYVVTFPSKEEVQSQGKNAQKILVTPWDYRIPKIRISTQQAETLQDFRVVVRIDSWESTSVYPNGHFVRVLGRIGDLEGEIATILVENSISVIPFSEAQMCEMPVNTPESPWKVSPEEEQKRKDLRKSHLVFSIDPKGCEDVDDTLSVRTLNNGNLELGVHIADVTHFVAPNSYIDIEARTRATTYYLADRRYDMLPSVLSADLCSLLGGVDRYAVSIMWELDKASYEIKKVWYGRTIIRSAYKLFYEAAQELLDGNLSVVDDIPEFKDLDEKSRQAKLEELVWAIGKLTDIARHVRAKRDGCGALELEGVEVCVQLDDKKNIHDLIPKQPLEVHETVAECMILANHWVAKKIWESFPHQALLRQHPPPHQEFFSELRECAKAKGFFIDTRSNKTLADSLDNANDPHDPIVNRLLRSMATQAMSNALYFSTGSCAEEEFHHYGLALDKYTHFTSPIRRYSDIVVHRLLMAAISKDKKMEIKGNLFSNKDLEELCRHINNRNQAAQHSQKQSTELFQCMYFKDKDPATEERCISDGVIYSIRTNGVLLFIPRFGIKGAAYLKNKDGLVISCGPDSCSEWKPGSLQRFQNKITSTTTDGESVTFHLFDHVTVRISIQASRCHSDTIRLEIISNKPYKIPNTELIHQSSPLLKSELVKEVTKSVEEAQLAQEVKVNIIQEEYQEYRQTKGRSLYTLLEEIRDLALLDVSNNYGI

Target ORF information:

RefSeq Version	NM_001323937.1
Organism	Homo sapiens(human)
Definition	Homo sapiens DIS3 like exosome 3'-5' exoribonuclease (DIS3L), transcript variant 4, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001323937.1

ORF Insert Sequence:

ATGCAGACAG CTTGTCAAGC TGTGCAGCAT CAAAGAGGCA GGAGGAGCAT ATACAACGCA 
GCTGTTTGGT ACTATCATCA CTGCCAGGAC AGGATGCCAA TTGTTATGGT GACAGAAGAT 
GAAGAGGCAA TTCAGCAGTA TGGAAGTGAA ACAGAAGGAG TATTCGTGAT TACTTTCAAG 
AATTACCTGG ACAATTTCTG GCCTGATTTA AAAGCTGCCC ACGAGCTTTG TGATTCTATC 
CTTCAGTCTC GACGGGAGAG AGAGAATGAG AGTCAGGAGA GCCATGGGAA GGAGTACCCA 
GAACATCTTC CCCTGGAAGT GTTAGAAGCT GGGATTAAAT CTGGACGCTA TATCCAGGGA 
ATTCTGAATG TCAACAAACA CAGAGCCCAA ATAGAAGCTT TTGTTCGACT TCAAGGAGCC 
AGCAGTAAAG ATTCAGATTT AGTCAGTGAC ATCCTAATCC ACGGGATGAA GGCTCGAAAC 
CGCTCAATTC ATGGAGATGT GGTAGTTGTG GAGCTGCTTC CTAAAAATGA ATGGAAAGGA 
AGAACCGTAG CCCTGTGTGA GAATGACTGT GACGACAAGG CTTCGGGCGA GTCCCCAAGT 
GAGCCCATGC CTACAGGTCG AGTGGTGGGC ATACTTCAGA AGAACTGGCG GGATTATGTG 
GTGACATTTC CGTCCAAAGA AGAGGTCCAA TCTCAGGGCA AAAATGCTCA GAAAATCCTG 
GTTACACCTT GGGATTACAG AATTCCCAAA ATTCGAATTA GCACTCAGCA AGCAGAAACC 
CTCCAGGACT TCAGGGTGGT CGTGCGCATC GATTCCTGGG AGTCAACATC TGTGTATCCA 
AATGGACATT TTGTGCGTGT TTTAGGAAGA ATCGGAGATC TGGAAGGGGA AATTGCAACC 
ATCCTGGTGG AAAACAGTAT TTCAGTTATT CCTTTCTCAG AAGCTCAGAT GTGTGAGATG 
CCAGTAAACA CACCAGAAAG TCCCTGGAAG GTGAGTCCTG AAGAGGAACA AAAACGTAAA 
GACTTGAGGA AAAGCCATCT CGTATTCAGC ATTGACCCCA AAGGTTGTGA AGATGTGGAT 
GACACACTCT CAGTCAGAAC CTTAAATAAT GGCAACCTGG AACTTGGGGT CCACATCGCA 
GATGTAACAC ACTTTGTGGC ACCAAATTCT TACATTGATA TTGAAGCTAG AACAAGGGCC 
ACCACTTATT ATCTAGCAGA TCGTCGCTAT GACATGCTGC CTTCCGTCCT CAGTGCAGAT 
TTGTGTTCCC TTCTGGGAGG CGTTGATAGG TATGCTGTAA GCATCATGTG GGAACTGGAT 
AAAGCCTCTT ATGAAATTAA GAAAGTGTGG TATGGCAGAA CCATTATTCG ATCAGCATAC 
AAACTGTTCT ATGAAGCAGC CCAAGAACTA CTGGATGGAA ACTTAAGCGT TGTTGATGAT 
ATTCCAGAAT TCAAAGACTT GGATGAGAAG AGCAGACAAG CCAAGCTGGA GGAGTTGGTG 
TGGGCAATTG GAAAGCTGAC CGACATAGCT CGCCATGTCA GAGCTAAACG AGACGGATGT 
GGTGCCCTGG AACTGGAAGG GGTAGAGGTT TGCGTACAGC TAGATGACAA AAAGAACATT 
CACGACCTCA TCCCCAAGCA GCCCCTGGAA GTCCACGAGA CAGTGGCTGA ATGCATGATC 
CTGGCCAACC ACTGGGTCGC CAAAAAGATC TGGGAGAGCT TCCCTCATCA GGCCTTGCTG 
CGCCAGCACC CTCCTCCACA CCAGGAGTTC TTTTCAGAAC TCCGGGAATG TGCTAAAGCC 
AAAGGCTTCT TCATAGATAC ACGGTCCAAT AAAACACTGG CTGATTCTCT GGATAATGCG 
AACGACCCCC ACGATCCCAT TGTGAACAGG CTACTGCGCT CCATGGCCAC GCAGGCCATG 
TCGAATGCTC TGTACTTCTC CACCGGATCC TGTGCGGAGG AGGAGTTCCA TCATTACGGT 
CTTGCATTAG ATAAATATAC CCACTTTACT TCTCCAATAA GAAGATATTC AGATATTGTA 
GTACACCGCT TGTTAATGGC AGCCATTTCA AAAGATAAGA AAATGGAAAT TAAGGGAAAT 
CTGTTCAGCA ACAAAGATCT TGAGGAATTA TGCAGACATA TCAACAACAG AAACCAAGCA 
GCACAGCATT CTCAGAAGCA GTCTACTGAG CTCTTCCAGT GCATGTACTT CAAAGACAAA 
GACCCTGCCA CCGAGGAGCG TTGCATATCT GACGGAGTTA TTTATTCAAT TAGAACAAAT 
GGTGTGCTTC TATTTATACC AAGGTTTGGG ATTAAAGGTG CTGCTTATCT AAAAAATAAA 
GATGGTTTAG TCATCTCATG TGGCCCAGAT AGCTGTTCTG AATGGAAACC AGGATCCCTT 
CAACGATTTC AAAACAAAAT TACCTCTACT ACAACAGATG GGGAATCTGT TACGTTCCAT 
TTGTTTGACC ATGTAACCGT AAGAATATCC ATACAGGCCT CACGTTGCCA TTCTGATACA 
ATCAGACTTG AAATAATTAG TAACAAACCA TACAAGATAC CAAATACAGA ACTTATTCAT 
CAGAGTTCCC CCTTGCTGAA GAGTGAGTTA GTGAAAGAAG TAACTAAATC TGTGGAAGAA 
GCTCAGCTTG CCCAAGAAGT CAAAGTAAAC ATCATTCAGG AGGAATATCA AGAATATCGC 
CAAACAAAGG GAAGGAGCCT ATACACACTT CTAGAGGAGA TACGGGACCT AGCTCTCCTG 
GATGTTTCAA ACAATTATGG AATATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

DIS3L ( NM_001323937.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_001310866.1 Homo sapiens DIS3 like exosome 3'-5' exoribonuclease (DIS3L), transcript variant 4, mRNA.

Price & Availability↑

CloneID	OHu82921
Clone ID Related Accession (Same CDS sequence)	NM_001323937.1 , NM_001323937.2
Accession Version	NM_001323937.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2787bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-09-27
Organism	Homo sapiens(human)
Product	DIS3-like exonuclease 1 isoform 5
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AC055855.9. On May 31, 2019 this sequence version replaced NM_001323937.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. ##Evidence-Data-START## Transcript exon combination :: SRR1803613.279618.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968968, SAMEA1970526 [ECO:0000348] ##Evidence-Data-END##

ATGCAGACAG CTTGTCAAGC TGTGCAGCAT CAAAGAGGCA GGAGGAGCAT ATACAACGCA 
GCTGTTTGGT ACTATCATCA CTGCCAGGAC AGGATGCCAA TTGTTATGGT GACAGAAGAT 
GAAGAGGCAA TTCAGCAGTA TGGAAGTGAA ACAGAAGGAG TATTCGTGAT TACTTTCAAG 
AATTACCTGG ACAATTTCTG GCCTGATTTA AAAGCTGCCC ACGAGCTTTG TGATTCTATC 
CTTCAGTCTC GACGGGAGAG AGAGAATGAG AGTCAGGAGA GCCATGGGAA GGAGTACCCA 
GAACATCTTC CCCTGGAAGT GTTAGAAGCT GGGATTAAAT CTGGACGCTA TATCCAGGGA 
ATTCTGAATG TCAACAAACA CAGAGCCCAA ATAGAAGCTT TTGTTCGACT TCAAGGAGCC 
AGCAGTAAAG ATTCAGATTT AGTCAGTGAC ATCCTAATCC ACGGGATGAA GGCTCGAAAC 
CGCTCAATTC ATGGAGATGT GGTAGTTGTG GAGCTGCTTC CTAAAAATGA ATGGAAAGGA 
AGAACCGTAG CCCTGTGTGA GAATGACTGT GACGACAAGG CTTCGGGCGA GTCCCCAAGT 
GAGCCCATGC CTACAGGTCG AGTGGTGGGC ATACTTCAGA AGAACTGGCG GGATTATGTG 
GTGACATTTC CGTCCAAAGA AGAGGTCCAA TCTCAGGGCA AAAATGCTCA GAAAATCCTG 
GTTACACCTT GGGATTACAG AATTCCCAAA ATTCGAATTA GCACTCAGCA AGCAGAAACC 
CTCCAGGACT TCAGGGTGGT CGTGCGCATC GATTCCTGGG AGTCAACATC TGTGTATCCA 
AATGGACATT TTGTGCGTGT TTTAGGAAGA ATCGGAGATC TGGAAGGGGA AATTGCAACC 
ATCCTGGTGG AAAACAGTAT TTCAGTTATT CCTTTCTCAG AAGCTCAGAT GTGTGAGATG 
CCAGTAAACA CACCAGAAAG TCCCTGGAAG GTGAGTCCTG AAGAGGAACA AAAACGTAAA 
GACTTGAGGA AAAGCCATCT CGTATTCAGC ATTGACCCCA AAGGTTGTGA AGATGTGGAT 
GACACACTCT CAGTCAGAAC CTTAAATAAT GGCAACCTGG AACTTGGGGT CCACATCGCA 
GATGTAACAC ACTTTGTGGC ACCAAATTCT TACATTGATA TTGAAGCTAG AACAAGGGCC 
ACCACTTATT ATCTAGCAGA TCGTCGCTAT GACATGCTGC CTTCCGTCCT CAGTGCAGAT 
TTGTGTTCCC TTCTGGGAGG CGTTGATAGG TATGCTGTAA GCATCATGTG GGAACTGGAT 
AAAGCCTCTT ATGAAATTAA GAAAGTGTGG TATGGCAGAA CCATTATTCG ATCAGCATAC 
AAACTGTTCT ATGAAGCAGC CCAAGAACTA CTGGATGGAA ACTTAAGCGT TGTTGATGAT 
ATTCCAGAAT TCAAAGACTT GGATGAGAAG AGCAGACAAG CCAAGCTGGA GGAGTTGGTG 
TGGGCAATTG GAAAGCTGAC CGACATAGCT CGCCATGTCA GAGCTAAACG AGACGGATGT 
GGTGCCCTGG AACTGGAAGG GGTAGAGGTT TGCGTACAGC TAGATGACAA AAAGAACATT 
CACGACCTCA TCCCCAAGCA GCCCCTGGAA GTCCACGAGA CAGTGGCTGA ATGCATGATC 
CTGGCCAACC ACTGGGTCGC CAAAAAGATC TGGGAGAGCT TCCCTCATCA GGCCTTGCTG 
CGCCAGCACC CTCCTCCACA CCAGGAGTTC TTTTCAGAAC TCCGGGAATG TGCTAAAGCC 
AAAGGCTTCT TCATAGATAC ACGGTCCAAT AAAACACTGG CTGATTCTCT GGATAATGCG 
AACGACCCCC ACGATCCCAT TGTGAACAGG CTACTGCGCT CCATGGCCAC GCAGGCCATG 
TCGAATGCTC TGTACTTCTC CACCGGATCC TGTGCGGAGG AGGAGTTCCA TCATTACGGT 
CTTGCATTAG ATAAATATAC CCACTTTACT TCTCCAATAA GAAGATATTC AGATATTGTA 
GTACACCGCT TGTTAATGGC AGCCATTTCA AAAGATAAGA AAATGGAAAT TAAGGGAAAT 
CTGTTCAGCA ACAAAGATCT TGAGGAATTA TGCAGACATA TCAACAACAG AAACCAAGCA 
GCACAGCATT CTCAGAAGCA GTCTACTGAG CTCTTCCAGT GCATGTACTT CAAAGACAAA 
GACCCTGCCA CCGAGGAGCG TTGCATATCT GACGGAGTTA TTTATTCAAT TAGAACAAAT 
GGTGTGCTTC TATTTATACC AAGGTTTGGG ATTAAAGGTG CTGCTTATCT AAAAAATAAA 
GATGGTTTAG TCATCTCATG TGGCCCAGAT AGCTGTTCTG AATGGAAACC AGGATCCCTT 
CAACGATTTC AAAACAAAAT TACCTCTACT ACAACAGATG GGGAATCTGT TACGTTCCAT 
TTGTTTGACC ATGTAACCGT AAGAATATCC ATACAGGCCT CACGTTGCCA TTCTGATACA 
ATCAGACTTG AAATAATTAG TAACAAACCA TACAAGATAC CAAATACAGA ACTTATTCAT 
CAGAGTTCCC CCTTGCTGAA GAGTGAGTTA GTGAAAGAAG TAACTAAATC TGTGGAAGAA 
GCTCAGCTTG CCCAAGAAGT CAAAGTAAAC ATCATTCAGG AGGAATATCA AGAATATCGC 
CAAACAAAGG GAAGGAGCCT ATACACACTT CTAGAGGAGA TACGGGACCT AGCTCTCCTG 
GATGTTTCAA ACAATTATGG AATATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001310866.1
CDS	170..2956
Translation	MQTACQAVQHQRGRRSIYNAAVWYYHHCQDRMPIVMVTEDEEAIQQYGSETEGVFVITFKNYLDNFWPDLKAAHELCDSILQSRRERENESQESHGKEYPEHLPLEVLEAGIKSGRYIQGILNVNKHRAQIEAFVRLQGASSKDSDLVSDILIHGMKARNRSIHGDVVVVELLPKNEWKGRTVALCENDCDDKASGESPSEPMPTGRVVGILQKNWRDYVVTFPSKEEVQSQGKNAQKILVTPWDYRIPKIRISTQQAETLQDFRVVVRIDSWESTSVYPNGHFVRVLGRIGDLEGEIATILVENSISVIPFSEAQMCEMPVNTPESPWKVSPEEEQKRKDLRKSHLVFSIDPKGCEDVDDTLSVRTLNNGNLELGVHIADVTHFVAPNSYIDIEARTRATTYYLADRRYDMLPSVLSADLCSLLGGVDRYAVSIMWELDKASYEIKKVWYGRTIIRSAYKLFYEAAQELLDGNLSVVDDIPEFKDLDEKSRQAKLEELVWAIGKLTDIARHVRAKRDGCGALELEGVEVCVQLDDKKNIHDLIPKQPLEVHETVAECMILANHWVAKKIWESFPHQALLRQHPPPHQEFFSELRECAKAKGFFIDTRSNKTLADSLDNANDPHDPIVNRLLRSMATQAMSNALYFSTGSCAEEEFHHYGLALDKYTHFTSPIRRYSDIVVHRLLMAAISKDKKMEIKGNLFSNKDLEELCRHINNRNQAAQHSQKQSTELFQCMYFKDKDPATEERCISDGVIYSIRTNGVLLFIPRFGIKGAAYLKNKDGLVISCGPDSCSEWKPGSLQRFQNKITSTTTDGESVTFHLFDHVTVRISIQASRCHSDTIRLEIISNKPYKIPNTELIHQSSPLLKSELVKEVTKSVEEAQLAQEVKVNIIQEEYQEYRQTKGRSLYTLLEEIRDLALLDVSNNYGI

Target ORF information:

RefSeq Version	NM_001323937.2
Organism	Homo sapiens(human)
Definition	Homo sapiens DIS3 like exosome 3'-5' exoribonuclease (DIS3L), transcript variant 4, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001323937.2

ORF Insert Sequence:

ATGCAGACAG CTTGTCAAGC TGTGCAGCAT CAAAGAGGCA GGAGGAGCAT ATACAACGCA 
GCTGTTTGGT ACTATCATCA CTGCCAGGAC AGGATGCCAA TTGTTATGGT GACAGAAGAT 
GAAGAGGCAA TTCAGCAGTA TGGAAGTGAA ACAGAAGGAG TATTCGTGAT TACTTTCAAG 
AATTACCTGG ACAATTTCTG GCCTGATTTA AAAGCTGCCC ACGAGCTTTG TGATTCTATC 
CTTCAGTCTC GACGGGAGAG AGAGAATGAG AGTCAGGAGA GCCATGGGAA GGAGTACCCA 
GAACATCTTC CCCTGGAAGT GTTAGAAGCT GGGATTAAAT CTGGACGCTA TATCCAGGGA 
ATTCTGAATG TCAACAAACA CAGAGCCCAA ATAGAAGCTT TTGTTCGACT TCAAGGAGCC 
AGCAGTAAAG ATTCAGATTT AGTCAGTGAC ATCCTAATCC ACGGGATGAA GGCTCGAAAC 
CGCTCAATTC ATGGAGATGT GGTAGTTGTG GAGCTGCTTC CTAAAAATGA ATGGAAAGGA 
AGAACCGTAG CCCTGTGTGA GAATGACTGT GACGACAAGG CTTCGGGCGA GTCCCCAAGT 
GAGCCCATGC CTACAGGTCG AGTGGTGGGC ATACTTCAGA AGAACTGGCG GGATTATGTG 
GTGACATTTC CGTCCAAAGA AGAGGTCCAA TCTCAGGGCA AAAATGCTCA GAAAATCCTG 
GTTACACCTT GGGATTACAG AATTCCCAAA ATTCGAATTA GCACTCAGCA AGCAGAAACC 
CTCCAGGACT TCAGGGTGGT CGTGCGCATC GATTCCTGGG AGTCAACATC TGTGTATCCA 
AATGGACATT TTGTGCGTGT TTTAGGAAGA ATCGGAGATC TGGAAGGGGA AATTGCAACC 
ATCCTGGTGG AAAACAGTAT TTCAGTTATT CCTTTCTCAG AAGCTCAGAT GTGTGAGATG 
CCAGTAAACA CACCAGAAAG TCCCTGGAAG GTGAGTCCTG AAGAGGAACA AAAACGTAAA 
GACTTGAGGA AAAGCCATCT CGTATTCAGC ATTGACCCCA AAGGTTGTGA AGATGTGGAT 
GACACACTCT CAGTCAGAAC CTTAAATAAT GGCAACCTGG AACTTGGGGT CCACATCGCA 
GATGTAACAC ACTTTGTGGC ACCAAATTCT TACATTGATA TTGAAGCTAG AACAAGGGCC 
ACCACTTATT ATCTAGCAGA TCGTCGCTAT GACATGCTGC CTTCCGTCCT CAGTGCAGAT 
TTGTGTTCCC TTCTGGGAGG CGTTGATAGG TATGCTGTAA GCATCATGTG GGAACTGGAT 
AAAGCCTCTT ATGAAATTAA GAAAGTGTGG TATGGCAGAA CCATTATTCG ATCAGCATAC 
AAACTGTTCT ATGAAGCAGC CCAAGAACTA CTGGATGGAA ACTTAAGCGT TGTTGATGAT 
ATTCCAGAAT TCAAAGACTT GGATGAGAAG AGCAGACAAG CCAAGCTGGA GGAGTTGGTG 
TGGGCAATTG GAAAGCTGAC CGACATAGCT CGCCATGTCA GAGCTAAACG AGACGGATGT 
GGTGCCCTGG AACTGGAAGG GGTAGAGGTT TGCGTACAGC TAGATGACAA AAAGAACATT 
CACGACCTCA TCCCCAAGCA GCCCCTGGAA GTCCACGAGA CAGTGGCTGA ATGCATGATC 
CTGGCCAACC ACTGGGTCGC CAAAAAGATC TGGGAGAGCT TCCCTCATCA GGCCTTGCTG 
CGCCAGCACC CTCCTCCACA CCAGGAGTTC TTTTCAGAAC TCCGGGAATG TGCTAAAGCC 
AAAGGCTTCT TCATAGATAC ACGGTCCAAT AAAACACTGG CTGATTCTCT GGATAATGCG 
AACGACCCCC ACGATCCCAT TGTGAACAGG CTACTGCGCT CCATGGCCAC GCAGGCCATG 
TCGAATGCTC TGTACTTCTC CACCGGATCC TGTGCGGAGG AGGAGTTCCA TCATTACGGT 
CTTGCATTAG ATAAATATAC CCACTTTACT TCTCCAATAA GAAGATATTC AGATATTGTA 
GTACACCGCT TGTTAATGGC AGCCATTTCA AAAGATAAGA AAATGGAAAT TAAGGGAAAT 
CTGTTCAGCA ACAAAGATCT TGAGGAATTA TGCAGACATA TCAACAACAG AAACCAAGCA 
GCACAGCATT CTCAGAAGCA GTCTACTGAG CTCTTCCAGT GCATGTACTT CAAAGACAAA 
GACCCTGCCA CCGAGGAGCG TTGCATATCT GACGGAGTTA TTTATTCAAT TAGAACAAAT 
GGTGTGCTTC TATTTATACC AAGGTTTGGG ATTAAAGGTG CTGCTTATCT AAAAAATAAA 
GATGGTTTAG TCATCTCATG TGGCCCAGAT AGCTGTTCTG AATGGAAACC AGGATCCCTT 
CAACGATTTC AAAACAAAAT TACCTCTACT ACAACAGATG GGGAATCTGT TACGTTCCAT 
TTGTTTGACC ATGTAACCGT AAGAATATCC ATACAGGCCT CACGTTGCCA TTCTGATACA 
ATCAGACTTG AAATAATTAG TAACAAACCA TACAAGATAC CAAATACAGA ACTTATTCAT 
CAGAGTTCCC CCTTGCTGAA GAGTGAGTTA GTGAAAGAAG TAACTAAATC TGTGGAAGAA 
GCTCAGCTTG CCCAAGAAGT CAAAGTAAAC ATCATTCAGG AGGAATATCA AGAATATCGC 
CAAACAAAGG GAAGGAGCCT ATACACACTT CTAGAGGAGA TACGGGACCT AGCTCTCCTG 
GATGTTTCAA ACAATTATGG AATATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

DIS3L ( NM_001323948.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001310877.1 Homo sapiens DIS3 like exosome 3'-5' exoribonuclease (DIS3L), transcript variant 13, mRNA.

Price & Availability↑

CloneID	OHu82922
Clone ID Related Accession (Same CDS sequence)	NM_001323948.1 , NM_001323948.2
Accession Version	NM_001323948.1	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2985bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2018-12-04
Organism	Homo sapiens(human)
Product	DIS3-like exonuclease 1 isoform 7
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AC055855.9. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. ##Evidence-Data-START## Transcript exon combination :: SRR1660807.172342.1, SRR1803614.61928.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968968, SAMEA1970526 [ECO:0000348] ##Evidence-Data-END##

ATGGGGAGGT CCCGAGCTGG GAGCCCCCGG GAGCTACAGG CCAGCTGCTG CCGCTGCGAA 
GCTGACATCG CCTGCTTTGC AGCCACAGAT GGGAAACTCT TGTCTAGTGA TGTGACTCAT 
TACGTGATCC CAGACTGGAA AGTTGTTCAA GATTATCTTG AGATCCTTGA GTTTCCTGAG 
TTGAAGGGAA TTATTTTCAT GCAGACAGCT TGTCAAGCTG TGCAGCATCA AAGAGGCAGG 
AGGAGCATAT ACAACGCAGC TGTTTGGTAC TATCATCACT GCCAGGACAG GATGCCAATT 
GTTATGGTGA CAGAAGATGA AGAGGCAATT CAGCAGTATG GAAGTGAAAC AGAAGGAGTA 
TTCGTGATTA CTTTCAAGAA TTACCTGGAC AATTTCTGGC CTGATTTAAA AGCTGCCCAC 
GAGCTTTGTG ATTCTATCCT TCAGTCTCGA CGGGAGAGAG AGAATGAGAG TCAGGAGAGC 
CATGGGAAGG AGTACCCAGA ACATCTTCCC CTGGAAGTGT TAGAAGCTGG GATTAAATCT 
GGACGCTATA TCCAGGGAAT TCTGAATGTC AACAAACACA GAGCCCAAAT AGAAGCTTTT 
GTTCGACTTC AAGGAGCCAG CAGTAAAGAT TCAGATTTAG TCAGTGACAT CCTAATCCAC 
GGGATGAAGG CTCGAAACCG CTCAATTCAT GGAGATGTGG TAGTTGTGGA GCTGCTTCCT 
AAAAATGAAT GGAAAGGAAG AACCGTAGCC CTGTGTGAGA ATGACTGTGA CGACAAGGCT 
TCGGGCGAGT CCCCAAGTGA GCCCATGCCT ACAGGTCGAG TGGTGGGCAT ACTTCAGAAG 
AACTGGCGGG ATTATGTGGT GACATTTCCG TCCAAAGAAG AGGTCCAATC TCAGGGCAAA 
AATGCTCAGA AAATCCTGGT TACACCTTGG GATTACAGAA TTCCCAAAAT TCGAATTAGC 
ACTCAGCAAG CAGAAACCCT CCAGGACTTC AGGGTGGTCG TGCGCATCGA TTCCTGGGAG 
TCAACATCTG TGTATCCAAA TGGACATTTT GTGCGTGTTT TAGGAAGAAT CGGAGATCTG 
GAAGGGGAAA TTGCAACCAT CCTGGTGGAA AACAGTATTT CAGTTATTCC TTTCTCAGAA 
GCTCAGATGT GTGAGATGCC AGTAAACACA CCAGAAAGTC CCTGGAAGGT GAGTCCTGAA 
GAGGAACAAA AACGTAAAGA CTTGAGGAAA AGCCATCTCG TATTCAGCAT TGACCCCAAA 
GGTTGTGAAG ATGTGGATGA CACACTCTCA GTCAGAACCT TAAATAATGG CAACCTGGAA 
CTTGGGGTCC ACATCGCAGA TGTAACACAC TTTGTGGCAC CAAATTCTTA CATTGATATT 
GAAGCTAGAA CAAGGGCCAC CACTTATTAT CTAGCAGATC GTCGCTATGA CATGCTGCCT 
TCCGTCCTCA GTGCAGATTT GTGTTCCCTT CTGGGAGGCG TTGATAGGTA TGCTGTAAGC 
ATCATGTGGG AACTGGATAA AGCCTCTTAT GAAATTAAGA AAGTGTGGTA TGGCAGAACC 
ATTATTCGAT CAGCATACAA ACTGTTCTAT GAAGCAGCCC AAGAACTACT GGATGGAAAC 
TTAAGCGTTG TTGATGATAT TCCAGAATTC AAAGACTTGG ATGAGAAGAG CAGACAAGCC 
AAGCTGGAGG AGTTGGTGTG GGCAATTGGA AAGCTGACCG ACATAGCTCG CCATGTCAGA 
GCTAAACGAG ACGGATGTGG TGCCCTGGAA CTGGAAGGGG TAGAGGTTTG CGTACAGCTA 
GATGACAAAA AGAACATTCA CGACCTCATC CCCAAGCAGC CCCTGGAAGT CCACGAGACA 
GTGGCTGAAT GCATGATCCT GGCCAACCAC TGGGTCGCCA AAAAGATCTG GGAGAGCTTC 
CCTCATCAGG CCTTGCTGCG CCAGCACCCT CCTCCACACC AGGAGTTCTT TTCAGAACTC 
CGGGAATGTG CTAAAGCCAA AGGCTTCTTC ATAGATACAC GGTCCAATAA AACACTGGCT 
GATTCTCTGG ATAATGCGAA CGACCCCCAC GATCCCATTG TGAACAGGCT ACTGCGCTCC 
ATGGCCACGC AGGCCATGTC GAATGCTCTG TACTTCTCCA CCGGATCCTG TGCGGAGGAG 
GAGTTCCATC ATTACGGTCT TGCATTAGAT AAATATACCC ACTTTACTTC TCCAATAAGA 
AGATATTCAG ATATTGTAGT ACACCGCTTG TTAATGGCAG CCATTTCAAA AGATAAGAAA 
ATGGAAATTA AGGGAAATCT GTTCAGCAAC AAAGATCTTG AGGAATTATG CAGACATATC 
AACAACAGAA ACCAAGCAGC ACAGCATTCT CAGAAGCAGT CTACTGAGCT CTTCCAGTGC 
ATGTACTTCA AAGACAAAGA CCCTGCCACC GAGGAGCGTT GCATATCTGA CGGAGTTATT 
TATTCAATTA GAACAAATGG TGTGCTTCTA TTTATACCAA GGTTTGGGAT TAAAGGTGCT 
GCTTATCTAA AAAATAAAGA TGGTTTAGTC ATCTCATGTG GCCCAGATAG CTGTTCTGAA 
TGGAAACCAG GATCCCTTCA ACGATTTCAA AACAAAATTA CCTCTACTAC AACAGATGGG 
GAATCTGTTA CGTTCCATTT GTTTGACCAT GTAACCGTAA GAATATCCAT ACAGGCCTCA 
CGTTGCCATT CTGATACAAT CAGACTTGAA ATAATTAGTA ACAAACCATA CAAGATACCA 
AATACAGAAC TTATTCATCA GAGTTCCCCC TTGCTGAAGA GTGAGTTAGT GAAAGAAGTA 
ACTAAATCTG TGGAAGAAGC TCAGCTTGCC CAAGAAGTCA AAGTAAACAT CATTCAGGAG 
GAATATCAAG AATATCGCCA AACAAAGGGA AGGAGCCTAT ACACACTTCT AGAGGAGATA 
CGGGACCTAG CTCTCCTGGA TGTTTCAAAC AATTATGGAA TATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001310877.1
CDS	268..3252
Translation	MGRSRAGSPRELQASCCRCEADIACFAATDGKLLSSDVTHYVIPDWKVVQDYLEILEFPELKGIIFMQTACQAVQHQRGRRSIYNAAVWYYHHCQDRMPIVMVTEDEEAIQQYGSETEGVFVITFKNYLDNFWPDLKAAHELCDSILQSRRERENESQESHGKEYPEHLPLEVLEAGIKSGRYIQGILNVNKHRAQIEAFVRLQGASSKDSDLVSDILIHGMKARNRSIHGDVVVVELLPKNEWKGRTVALCENDCDDKASGESPSEPMPTGRVVGILQKNWRDYVVTFPSKEEVQSQGKNAQKILVTPWDYRIPKIRISTQQAETLQDFRVVVRIDSWESTSVYPNGHFVRVLGRIGDLEGEIATILVENSISVIPFSEAQMCEMPVNTPESPWKVSPEEEQKRKDLRKSHLVFSIDPKGCEDVDDTLSVRTLNNGNLELGVHIADVTHFVAPNSYIDIEARTRATTYYLADRRYDMLPSVLSADLCSLLGGVDRYAVSIMWELDKASYEIKKVWYGRTIIRSAYKLFYEAAQELLDGNLSVVDDIPEFKDLDEKSRQAKLEELVWAIGKLTDIARHVRAKRDGCGALELEGVEVCVQLDDKKNIHDLIPKQPLEVHETVAECMILANHWVAKKIWESFPHQALLRQHPPPHQEFFSELRECAKAKGFFIDTRSNKTLADSLDNANDPHDPIVNRLLRSMATQAMSNALYFSTGSCAEEEFHHYGLALDKYTHFTSPIRRYSDIVVHRLLMAAISKDKKMEIKGNLFSNKDLEELCRHINNRNQAAQHSQKQSTELFQCMYFKDKDPATEERCISDGVIYSIRTNGVLLFIPRFGIKGAAYLKNKDGLVISCGPDSCSEWKPGSLQRFQNKITSTTTDGESVTFHLFDHVTVRISIQASRCHSDTIRLEIISNKPYKIPNTELIHQSSPLLKSELVKEVTKSVEEAQLAQEVKVNIIQEEYQEYRQTKGRSLYTLLEEIRDLALLDVSNNYGI

Target ORF information:

RefSeq Version	NM_001323948.1
Organism	Homo sapiens(human)
Definition	Homo sapiens DIS3 like exosome 3'-5' exoribonuclease (DIS3L), transcript variant 13, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001323948.1

ORF Insert Sequence:

ATGGGGAGGT CCCGAGCTGG GAGCCCCCGG GAGCTACAGG CCAGCTGCTG CCGCTGCGAA 
GCTGACATCG CCTGCTTTGC AGCCACAGAT GGGAAACTCT TGTCTAGTGA TGTGACTCAT 
TACGTGATCC CAGACTGGAA AGTTGTTCAA GATTATCTTG AGATCCTTGA GTTTCCTGAG 
TTGAAGGGAA TTATTTTCAT GCAGACAGCT TGTCAAGCTG TGCAGCATCA AAGAGGCAGG 
AGGAGCATAT ACAACGCAGC TGTTTGGTAC TATCATCACT GCCAGGACAG GATGCCAATT 
GTTATGGTGA CAGAAGATGA AGAGGCAATT CAGCAGTATG GAAGTGAAAC AGAAGGAGTA 
TTCGTGATTA CTTTCAAGAA TTACCTGGAC AATTTCTGGC CTGATTTAAA AGCTGCCCAC 
GAGCTTTGTG ATTCTATCCT TCAGTCTCGA CGGGAGAGAG AGAATGAGAG TCAGGAGAGC 
CATGGGAAGG AGTACCCAGA ACATCTTCCC CTGGAAGTGT TAGAAGCTGG GATTAAATCT 
GGACGCTATA TCCAGGGAAT TCTGAATGTC AACAAACACA GAGCCCAAAT AGAAGCTTTT 
GTTCGACTTC AAGGAGCCAG CAGTAAAGAT TCAGATTTAG TCAGTGACAT CCTAATCCAC 
GGGATGAAGG CTCGAAACCG CTCAATTCAT GGAGATGTGG TAGTTGTGGA GCTGCTTCCT 
AAAAATGAAT GGAAAGGAAG AACCGTAGCC CTGTGTGAGA ATGACTGTGA CGACAAGGCT 
TCGGGCGAGT CCCCAAGTGA GCCCATGCCT ACAGGTCGAG TGGTGGGCAT ACTTCAGAAG 
AACTGGCGGG ATTATGTGGT GACATTTCCG TCCAAAGAAG AGGTCCAATC TCAGGGCAAA 
AATGCTCAGA AAATCCTGGT TACACCTTGG GATTACAGAA TTCCCAAAAT TCGAATTAGC 
ACTCAGCAAG CAGAAACCCT CCAGGACTTC AGGGTGGTCG TGCGCATCGA TTCCTGGGAG 
TCAACATCTG TGTATCCAAA TGGACATTTT GTGCGTGTTT TAGGAAGAAT CGGAGATCTG 
GAAGGGGAAA TTGCAACCAT CCTGGTGGAA AACAGTATTT CAGTTATTCC TTTCTCAGAA 
GCTCAGATGT GTGAGATGCC AGTAAACACA CCAGAAAGTC CCTGGAAGGT GAGTCCTGAA 
GAGGAACAAA AACGTAAAGA CTTGAGGAAA AGCCATCTCG TATTCAGCAT TGACCCCAAA 
GGTTGTGAAG ATGTGGATGA CACACTCTCA GTCAGAACCT TAAATAATGG CAACCTGGAA 
CTTGGGGTCC ACATCGCAGA TGTAACACAC TTTGTGGCAC CAAATTCTTA CATTGATATT 
GAAGCTAGAA CAAGGGCCAC CACTTATTAT CTAGCAGATC GTCGCTATGA CATGCTGCCT 
TCCGTCCTCA GTGCAGATTT GTGTTCCCTT CTGGGAGGCG TTGATAGGTA TGCTGTAAGC 
ATCATGTGGG AACTGGATAA AGCCTCTTAT GAAATTAAGA AAGTGTGGTA TGGCAGAACC 
ATTATTCGAT CAGCATACAA ACTGTTCTAT GAAGCAGCCC AAGAACTACT GGATGGAAAC 
TTAAGCGTTG TTGATGATAT TCCAGAATTC AAAGACTTGG ATGAGAAGAG CAGACAAGCC 
AAGCTGGAGG AGTTGGTGTG GGCAATTGGA AAGCTGACCG ACATAGCTCG CCATGTCAGA 
GCTAAACGAG ACGGATGTGG TGCCCTGGAA CTGGAAGGGG TAGAGGTTTG CGTACAGCTA 
GATGACAAAA AGAACATTCA CGACCTCATC CCCAAGCAGC CCCTGGAAGT CCACGAGACA 
GTGGCTGAAT GCATGATCCT GGCCAACCAC TGGGTCGCCA AAAAGATCTG GGAGAGCTTC 
CCTCATCAGG CCTTGCTGCG CCAGCACCCT CCTCCACACC AGGAGTTCTT TTCAGAACTC 
CGGGAATGTG CTAAAGCCAA AGGCTTCTTC ATAGATACAC GGTCCAATAA AACACTGGCT 
GATTCTCTGG ATAATGCGAA CGACCCCCAC GATCCCATTG TGAACAGGCT ACTGCGCTCC 
ATGGCCACGC AGGCCATGTC GAATGCTCTG TACTTCTCCA CCGGATCCTG TGCGGAGGAG 
GAGTTCCATC ATTACGGTCT TGCATTAGAT AAATATACCC ACTTTACTTC TCCAATAAGA 
AGATATTCAG ATATTGTAGT ACACCGCTTG TTAATGGCAG CCATTTCAAA AGATAAGAAA 
ATGGAAATTA AGGGAAATCT GTTCAGCAAC AAAGATCTTG AGGAATTATG CAGACATATC 
AACAACAGAA ACCAAGCAGC ACAGCATTCT CAGAAGCAGT CTACTGAGCT CTTCCAGTGC 
ATGTACTTCA AAGACAAAGA CCCTGCCACC GAGGAGCGTT GCATATCTGA CGGAGTTATT 
TATTCAATTA GAACAAATGG TGTGCTTCTA TTTATACCAA GGTTTGGGAT TAAAGGTGCT 
GCTTATCTAA AAAATAAAGA TGGTTTAGTC ATCTCATGTG GCCCAGATAG CTGTTCTGAA 
TGGAAACCAG GATCCCTTCA ACGATTTCAA AACAAAATTA CCTCTACTAC AACAGATGGG 
GAATCTGTTA CGTTCCATTT GTTTGACCAT GTAACCGTAA GAATATCCAT ACAGGCCTCA 
CGTTGCCATT CTGATACAAT CAGACTTGAA ATAATTAGTA ACAAACCATA CAAGATACCA 
AATACAGAAC TTATTCATCA GAGTTCCCCC TTGCTGAAGA GTGAGTTAGT GAAAGAAGTA 
ACTAAATCTG TGGAAGAAGC TCAGCTTGCC CAAGAAGTCA AAGTAAACAT CATTCAGGAG 
GAATATCAAG AATATCGCCA AACAAAGGGA AGGAGCCTAT ACACACTTCT AGAGGAGATA 
CGGGACCTAG CTCTCCTGGA TGTTTCAAAC AATTATGGAA TATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

DIS3L ( NM_001323948.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_001310877.1 Homo sapiens DIS3 like exosome 3'-5' exoribonuclease (DIS3L), transcript variant 13, mRNA.

Price & Availability↑

CloneID	OHu82922
Clone ID Related Accession (Same CDS sequence)	NM_001323948.1 , NM_001323948.2
Accession Version	NM_001323948.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2985bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-09-28
Organism	Homo sapiens(human)
Product	DIS3-like exonuclease 1 isoform 7
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AC055855.9. On Jun 1, 2019 this sequence version replaced NM_001323948.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. ##Evidence-Data-START## Transcript exon combination :: SRR1803614.61928.1, SRR1660807.172342.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968968, SAMEA1970526 [ECO:0000348] ##Evidence-Data-END##

ATGGGGAGGT CCCGAGCTGG GAGCCCCCGG GAGCTACAGG CCAGCTGCTG CCGCTGCGAA 
GCTGACATCG CCTGCTTTGC AGCCACAGAT GGGAAACTCT TGTCTAGTGA TGTGACTCAT 
TACGTGATCC CAGACTGGAA AGTTGTTCAA GATTATCTTG AGATCCTTGA GTTTCCTGAG 
TTGAAGGGAA TTATTTTCAT GCAGACAGCT TGTCAAGCTG TGCAGCATCA AAGAGGCAGG 
AGGAGCATAT ACAACGCAGC TGTTTGGTAC TATCATCACT GCCAGGACAG GATGCCAATT 
GTTATGGTGA CAGAAGATGA AGAGGCAATT CAGCAGTATG GAAGTGAAAC AGAAGGAGTA 
TTCGTGATTA CTTTCAAGAA TTACCTGGAC AATTTCTGGC CTGATTTAAA AGCTGCCCAC 
GAGCTTTGTG ATTCTATCCT TCAGTCTCGA CGGGAGAGAG AGAATGAGAG TCAGGAGAGC 
CATGGGAAGG AGTACCCAGA ACATCTTCCC CTGGAAGTGT TAGAAGCTGG GATTAAATCT 
GGACGCTATA TCCAGGGAAT TCTGAATGTC AACAAACACA GAGCCCAAAT AGAAGCTTTT 
GTTCGACTTC AAGGAGCCAG CAGTAAAGAT TCAGATTTAG TCAGTGACAT CCTAATCCAC 
GGGATGAAGG CTCGAAACCG CTCAATTCAT GGAGATGTGG TAGTTGTGGA GCTGCTTCCT 
AAAAATGAAT GGAAAGGAAG AACCGTAGCC CTGTGTGAGA ATGACTGTGA CGACAAGGCT 
TCGGGCGAGT CCCCAAGTGA GCCCATGCCT ACAGGTCGAG TGGTGGGCAT ACTTCAGAAG 
AACTGGCGGG ATTATGTGGT GACATTTCCG TCCAAAGAAG AGGTCCAATC TCAGGGCAAA 
AATGCTCAGA AAATCCTGGT TACACCTTGG GATTACAGAA TTCCCAAAAT TCGAATTAGC 
ACTCAGCAAG CAGAAACCCT CCAGGACTTC AGGGTGGTCG TGCGCATCGA TTCCTGGGAG 
TCAACATCTG TGTATCCAAA TGGACATTTT GTGCGTGTTT TAGGAAGAAT CGGAGATCTG 
GAAGGGGAAA TTGCAACCAT CCTGGTGGAA AACAGTATTT CAGTTATTCC TTTCTCAGAA 
GCTCAGATGT GTGAGATGCC AGTAAACACA CCAGAAAGTC CCTGGAAGGT GAGTCCTGAA 
GAGGAACAAA AACGTAAAGA CTTGAGGAAA AGCCATCTCG TATTCAGCAT TGACCCCAAA 
GGTTGTGAAG ATGTGGATGA CACACTCTCA GTCAGAACCT TAAATAATGG CAACCTGGAA 
CTTGGGGTCC ACATCGCAGA TGTAACACAC TTTGTGGCAC CAAATTCTTA CATTGATATT 
GAAGCTAGAA CAAGGGCCAC CACTTATTAT CTAGCAGATC GTCGCTATGA CATGCTGCCT 
TCCGTCCTCA GTGCAGATTT GTGTTCCCTT CTGGGAGGCG TTGATAGGTA TGCTGTAAGC 
ATCATGTGGG AACTGGATAA AGCCTCTTAT GAAATTAAGA AAGTGTGGTA TGGCAGAACC 
ATTATTCGAT CAGCATACAA ACTGTTCTAT GAAGCAGCCC AAGAACTACT GGATGGAAAC 
TTAAGCGTTG TTGATGATAT TCCAGAATTC AAAGACTTGG ATGAGAAGAG CAGACAAGCC 
AAGCTGGAGG AGTTGGTGTG GGCAATTGGA AAGCTGACCG ACATAGCTCG CCATGTCAGA 
GCTAAACGAG ACGGATGTGG TGCCCTGGAA CTGGAAGGGG TAGAGGTTTG CGTACAGCTA 
GATGACAAAA AGAACATTCA CGACCTCATC CCCAAGCAGC CCCTGGAAGT CCACGAGACA 
GTGGCTGAAT GCATGATCCT GGCCAACCAC TGGGTCGCCA AAAAGATCTG GGAGAGCTTC 
CCTCATCAGG CCTTGCTGCG CCAGCACCCT CCTCCACACC AGGAGTTCTT TTCAGAACTC 
CGGGAATGTG CTAAAGCCAA AGGCTTCTTC ATAGATACAC GGTCCAATAA AACACTGGCT 
GATTCTCTGG ATAATGCGAA CGACCCCCAC GATCCCATTG TGAACAGGCT ACTGCGCTCC 
ATGGCCACGC AGGCCATGTC GAATGCTCTG TACTTCTCCA CCGGATCCTG TGCGGAGGAG 
GAGTTCCATC ATTACGGTCT TGCATTAGAT AAATATACCC ACTTTACTTC TCCAATAAGA 
AGATATTCAG ATATTGTAGT ACACCGCTTG TTAATGGCAG CCATTTCAAA AGATAAGAAA 
ATGGAAATTA AGGGAAATCT GTTCAGCAAC AAAGATCTTG AGGAATTATG CAGACATATC 
AACAACAGAA ACCAAGCAGC ACAGCATTCT CAGAAGCAGT CTACTGAGCT CTTCCAGTGC 
ATGTACTTCA AAGACAAAGA CCCTGCCACC GAGGAGCGTT GCATATCTGA CGGAGTTATT 
TATTCAATTA GAACAAATGG TGTGCTTCTA TTTATACCAA GGTTTGGGAT TAAAGGTGCT 
GCTTATCTAA AAAATAAAGA TGGTTTAGTC ATCTCATGTG GCCCAGATAG CTGTTCTGAA 
TGGAAACCAG GATCCCTTCA ACGATTTCAA AACAAAATTA CCTCTACTAC AACAGATGGG 
GAATCTGTTA CGTTCCATTT GTTTGACCAT GTAACCGTAA GAATATCCAT ACAGGCCTCA 
CGTTGCCATT CTGATACAAT CAGACTTGAA ATAATTAGTA ACAAACCATA CAAGATACCA 
AATACAGAAC TTATTCATCA GAGTTCCCCC TTGCTGAAGA GTGAGTTAGT GAAAGAAGTA 
ACTAAATCTG TGGAAGAAGC TCAGCTTGCC CAAGAAGTCA AAGTAAACAT CATTCAGGAG 
GAATATCAAG AATATCGCCA AACAAAGGGA AGGAGCCTAT ACACACTTCT AGAGGAGATA 
CGGGACCTAG CTCTCCTGGA TGTTTCAAAC AATTATGGAA TATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001310877.1
CDS	273..3257
Translation	MGRSRAGSPRELQASCCRCEADIACFAATDGKLLSSDVTHYVIPDWKVVQDYLEILEFPELKGIIFMQTACQAVQHQRGRRSIYNAAVWYYHHCQDRMPIVMVTEDEEAIQQYGSETEGVFVITFKNYLDNFWPDLKAAHELCDSILQSRRERENESQESHGKEYPEHLPLEVLEAGIKSGRYIQGILNVNKHRAQIEAFVRLQGASSKDSDLVSDILIHGMKARNRSIHGDVVVVELLPKNEWKGRTVALCENDCDDKASGESPSEPMPTGRVVGILQKNWRDYVVTFPSKEEVQSQGKNAQKILVTPWDYRIPKIRISTQQAETLQDFRVVVRIDSWESTSVYPNGHFVRVLGRIGDLEGEIATILVENSISVIPFSEAQMCEMPVNTPESPWKVSPEEEQKRKDLRKSHLVFSIDPKGCEDVDDTLSVRTLNNGNLELGVHIADVTHFVAPNSYIDIEARTRATTYYLADRRYDMLPSVLSADLCSLLGGVDRYAVSIMWELDKASYEIKKVWYGRTIIRSAYKLFYEAAQELLDGNLSVVDDIPEFKDLDEKSRQAKLEELVWAIGKLTDIARHVRAKRDGCGALELEGVEVCVQLDDKKNIHDLIPKQPLEVHETVAECMILANHWVAKKIWESFPHQALLRQHPPPHQEFFSELRECAKAKGFFIDTRSNKTLADSLDNANDPHDPIVNRLLRSMATQAMSNALYFSTGSCAEEEFHHYGLALDKYTHFTSPIRRYSDIVVHRLLMAAISKDKKMEIKGNLFSNKDLEELCRHINNRNQAAQHSQKQSTELFQCMYFKDKDPATEERCISDGVIYSIRTNGVLLFIPRFGIKGAAYLKNKDGLVISCGPDSCSEWKPGSLQRFQNKITSTTTDGESVTFHLFDHVTVRISIQASRCHSDTIRLEIISNKPYKIPNTELIHQSSPLLKSELVKEVTKSVEEAQLAQEVKVNIIQEEYQEYRQTKGRSLYTLLEEIRDLALLDVSNNYGI

Target ORF information:

RefSeq Version	NM_001323948.2
Organism	Homo sapiens(human)
Definition	Homo sapiens DIS3 like exosome 3'-5' exoribonuclease (DIS3L), transcript variant 13, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001323948.2

ORF Insert Sequence:

ATGGGGAGGT CCCGAGCTGG GAGCCCCCGG GAGCTACAGG CCAGCTGCTG CCGCTGCGAA 
GCTGACATCG CCTGCTTTGC AGCCACAGAT GGGAAACTCT TGTCTAGTGA TGTGACTCAT 
TACGTGATCC CAGACTGGAA AGTTGTTCAA GATTATCTTG AGATCCTTGA GTTTCCTGAG 
TTGAAGGGAA TTATTTTCAT GCAGACAGCT TGTCAAGCTG TGCAGCATCA AAGAGGCAGG 
AGGAGCATAT ACAACGCAGC TGTTTGGTAC TATCATCACT GCCAGGACAG GATGCCAATT 
GTTATGGTGA CAGAAGATGA AGAGGCAATT CAGCAGTATG GAAGTGAAAC AGAAGGAGTA 
TTCGTGATTA CTTTCAAGAA TTACCTGGAC AATTTCTGGC CTGATTTAAA AGCTGCCCAC 
GAGCTTTGTG ATTCTATCCT TCAGTCTCGA CGGGAGAGAG AGAATGAGAG TCAGGAGAGC 
CATGGGAAGG AGTACCCAGA ACATCTTCCC CTGGAAGTGT TAGAAGCTGG GATTAAATCT 
GGACGCTATA TCCAGGGAAT TCTGAATGTC AACAAACACA GAGCCCAAAT AGAAGCTTTT 
GTTCGACTTC AAGGAGCCAG CAGTAAAGAT TCAGATTTAG TCAGTGACAT CCTAATCCAC 
GGGATGAAGG CTCGAAACCG CTCAATTCAT GGAGATGTGG TAGTTGTGGA GCTGCTTCCT 
AAAAATGAAT GGAAAGGAAG AACCGTAGCC CTGTGTGAGA ATGACTGTGA CGACAAGGCT 
TCGGGCGAGT CCCCAAGTGA GCCCATGCCT ACAGGTCGAG TGGTGGGCAT ACTTCAGAAG 
AACTGGCGGG ATTATGTGGT GACATTTCCG TCCAAAGAAG AGGTCCAATC TCAGGGCAAA 
AATGCTCAGA AAATCCTGGT TACACCTTGG GATTACAGAA TTCCCAAAAT TCGAATTAGC 
ACTCAGCAAG CAGAAACCCT CCAGGACTTC AGGGTGGTCG TGCGCATCGA TTCCTGGGAG 
TCAACATCTG TGTATCCAAA TGGACATTTT GTGCGTGTTT TAGGAAGAAT CGGAGATCTG 
GAAGGGGAAA TTGCAACCAT CCTGGTGGAA AACAGTATTT CAGTTATTCC TTTCTCAGAA 
GCTCAGATGT GTGAGATGCC AGTAAACACA CCAGAAAGTC CCTGGAAGGT GAGTCCTGAA 
GAGGAACAAA AACGTAAAGA CTTGAGGAAA AGCCATCTCG TATTCAGCAT TGACCCCAAA 
GGTTGTGAAG ATGTGGATGA CACACTCTCA GTCAGAACCT TAAATAATGG CAACCTGGAA 
CTTGGGGTCC ACATCGCAGA TGTAACACAC TTTGTGGCAC CAAATTCTTA CATTGATATT 
GAAGCTAGAA CAAGGGCCAC CACTTATTAT CTAGCAGATC GTCGCTATGA CATGCTGCCT 
TCCGTCCTCA GTGCAGATTT GTGTTCCCTT CTGGGAGGCG TTGATAGGTA TGCTGTAAGC 
ATCATGTGGG AACTGGATAA AGCCTCTTAT GAAATTAAGA AAGTGTGGTA TGGCAGAACC 
ATTATTCGAT CAGCATACAA ACTGTTCTAT GAAGCAGCCC AAGAACTACT GGATGGAAAC 
TTAAGCGTTG TTGATGATAT TCCAGAATTC AAAGACTTGG ATGAGAAGAG CAGACAAGCC 
AAGCTGGAGG AGTTGGTGTG GGCAATTGGA AAGCTGACCG ACATAGCTCG CCATGTCAGA 
GCTAAACGAG ACGGATGTGG TGCCCTGGAA CTGGAAGGGG TAGAGGTTTG CGTACAGCTA 
GATGACAAAA AGAACATTCA CGACCTCATC CCCAAGCAGC CCCTGGAAGT CCACGAGACA 
GTGGCTGAAT GCATGATCCT GGCCAACCAC TGGGTCGCCA AAAAGATCTG GGAGAGCTTC 
CCTCATCAGG CCTTGCTGCG CCAGCACCCT CCTCCACACC AGGAGTTCTT TTCAGAACTC 
CGGGAATGTG CTAAAGCCAA AGGCTTCTTC ATAGATACAC GGTCCAATAA AACACTGGCT 
GATTCTCTGG ATAATGCGAA CGACCCCCAC GATCCCATTG TGAACAGGCT ACTGCGCTCC 
ATGGCCACGC AGGCCATGTC GAATGCTCTG TACTTCTCCA CCGGATCCTG TGCGGAGGAG 
GAGTTCCATC ATTACGGTCT TGCATTAGAT AAATATACCC ACTTTACTTC TCCAATAAGA 
AGATATTCAG ATATTGTAGT ACACCGCTTG TTAATGGCAG CCATTTCAAA AGATAAGAAA 
ATGGAAATTA AGGGAAATCT GTTCAGCAAC AAAGATCTTG AGGAATTATG CAGACATATC 
AACAACAGAA ACCAAGCAGC ACAGCATTCT CAGAAGCAGT CTACTGAGCT CTTCCAGTGC 
ATGTACTTCA AAGACAAAGA CCCTGCCACC GAGGAGCGTT GCATATCTGA CGGAGTTATT 
TATTCAATTA GAACAAATGG TGTGCTTCTA TTTATACCAA GGTTTGGGAT TAAAGGTGCT 
GCTTATCTAA AAAATAAAGA TGGTTTAGTC ATCTCATGTG GCCCAGATAG CTGTTCTGAA 
TGGAAACCAG GATCCCTTCA ACGATTTCAA AACAAAATTA CCTCTACTAC AACAGATGGG 
GAATCTGTTA CGTTCCATTT GTTTGACCAT GTAACCGTAA GAATATCCAT ACAGGCCTCA 
CGTTGCCATT CTGATACAAT CAGACTTGAA ATAATTAGTA ACAAACCATA CAAGATACCA 
AATACAGAAC TTATTCATCA GAGTTCCCCC TTGCTGAAGA GTGAGTTAGT GAAAGAAGTA 
ACTAAATCTG TGGAAGAAGC TCAGCTTGCC CAAGAAGTCA AAGTAAACAT CATTCAGGAG 
GAATATCAAG AATATCGCCA AACAAAGGGA AGGAGCCTAT ACACACTTCT AGAGGAGATA 
CGGGACCTAG CTCTCCTGGA TGTTTCAAAC AATTATGGAA TATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

DIS3L ( NM_001323940.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001310869.1 Homo sapiens DIS3 like exosome 3'-5' exoribonuclease (DIS3L), transcript variant 7, mRNA.

Price & Availability↑

CloneID	OHu82923
Clone ID Related Accession (Same CDS sequence)	NM_001323940.1 , NM_001323943.2 , NM_001323943.1 , NM_001323940.2
Accession Version	NM_001323940.1	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2055bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2018-12-04
Organism	Homo sapiens(human)
Product	DIS3-like exonuclease 1 isoform 4
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AC055855.9. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. ##Evidence-Data-START## Transcript exon combination :: SRR1803616.243516.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968968, SAMEA2142586 [ECO:0000348] ##Evidence-Data-END##

ATGACTGTGA CGACAAGGCT TCGGGCGAGT CCCCAAGTGA GCCCATGCCT ACAGGACTTC 
AGGGTGGTCG TGCGCATCGA TTCCTGGGAG TCAACATCTG TGTATCCAAA TGGACATTTT 
GTGCGTGTTT TAGGAAGAAT CGGAGATCTG GAAGGGGAAA TTGCAACCAT CCTGGTGGAA 
AACAGTATTT CAGTTATTCC TTTCTCAGAA GCTCAGATGT GTGAGATGCC AGTAAACACA 
CCAGAAAGTC CCTGGAAGGT GAGTCCTGAA GAGGAACAAA AACGTAAAGA CTTGAGGAAA 
AGCCATCTCG TATTCAGCAT TGACCCCAAA GGTTGTGAAG ATGTGGATGA CACACTCTCA 
GTCAGAACCT TAAATAATGG CAACCTGGAA CTTGGGGTCC ACATCGCAGA TGTAACACAC 
TTTGTGGCAC CAAATTCTTA CATTGATATT GAAGCTAGAA CAAGGGCCAC CACTTATTAT 
CTAGCAGATC GTCGCTATGA CATGCTGCCT TCCGTCCTCA GTGCAGATTT GTGTTCCCTT 
CTGGGAGGCG TTGATAGGTA TGCTGTAAGC ATCATGTGGG AACTGGATAA AGCCTCTTAT 
GAAATTAAGA AAGTGTGGTA TGGCAGAACC ATTATTCGAT CAGCATACAA ACTGTTCTAT 
GAAGCAGCCC AAGAACTACT GGATGGAAAC TTAAGCGTTG TTGATGATAT TCCAGAATTC 
AAAGACTTGG ATGAGAAGAG CAGACAAGCC AAGCTGGAGG AGTTGGTGTG GGCAATTGGA 
AAGCTGACCG ACATAGCTCG CCATGTCAGA GCTAAACGAG ACGGATGTGG TGCCCTGGAA 
CTGGAAGGGG TAGAGGTTTG CGTACAGCTA GATGACAAAA AGAACATTCA CGACCTCATC 
CCCAAGCAGC CCCTGGAAGT CCACGAGACA GTGGCTGAAT GCATGATCCT GGCCAACCAC 
TGGGTCGCCA AAAAGATCTG GGAGAGCTTC CCTCATCAGG CCTTGCTGCG CCAGCACCCT 
CCTCCACACC AGGAGTTCTT TTCAGAACTC CGGGAATGTG CTAAAGCCAA AGGCTTCTTC 
ATAGATACAC GGTCCAATAA AACACTGGCT GATTCTCTGG ATAATGCGAA CGACCCCCAC 
GATCCCATTG TGAACAGGCT ACTGCGCTCC ATGGCCACGC AGGCCATGTC GAATGCTCTG 
TACTTCTCCA CCGGATCCTG TGCGGAGGAG GAGTTCCATC ATTACGGTCT TGCATTAGAT 
AAATATACCC ACTTTACTTC TCCAATAAGA AGATATTCAG ATATTGTAGT ACACCGCTTG 
TTAATGGCAG CCATTTCAAA AGATAAGAAA ATGGAAATTA AGGGAAATCT GTTCAGCAAC 
AAAGATCTTG AGGAATTATG CAGACATATC AACAACAGAA ACCAAGCAGC ACAGCATTCT 
CAGAAGCAGT CTACTGAGCT CTTCCAGTGC ATGTACTTCA AAGACAAAGA CCCTGCCACC 
GAGGAGCGTT GCATATCTGA CGGAGTTATT TATTCAATTA GAACAAATGG TGTGCTTCTA 
TTTATACCAA GGTTTGGGAT TAAAGGTGCT GCTTATCTAA AAAATAAAGA TGGTTTAGTC 
ATCTCATGTG GCCCAGATAG CTGTTCTGAA TGGAAACCAG GATCCCTTCA ACGATTTCAA 
AACAAAATTA CCTCTACTAC AACAGATGGG GAATCTGTTA CGTTCCATTT GTTTGACCAT 
GTAACCGTAA GAATATCCAT ACAGGCCTCA CGTTGCCATT CTGATACAAT CAGACTTGAA 
ATAATTAGTA ACAAACCATA CAAGATACCA AATACAGAAC TTATTCATCA GAGTTCCCCC 
TTGCTGAAGA GTGAGTTAGT GAAAGAAGTA ACTAAATCTG TGGAAGAAGC TCAGCTTGCC 
CAAGAAGTCA AAGTAAACAT CATTCAGGAG GAATATCAAG AATATCGCCA AACAAAGGGA 
AGGAGCCTAT ACACACTTCT AGAGGAGATA CGGGACCTAG CTCTCCTGGA TGTTTCAAAC 
AATTATGGAA TATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001310869.1
CDS	963..3017
Translation	MTVTTRLRASPQVSPCLQDFRVVVRIDSWESTSVYPNGHFVRVLGRIGDLEGEIATILVENSISVIPFSEAQMCEMPVNTPESPWKVSPEEEQKRKDLRKSHLVFSIDPKGCEDVDDTLSVRTLNNGNLELGVHIADVTHFVAPNSYIDIEARTRATTYYLADRRYDMLPSVLSADLCSLLGGVDRYAVSIMWELDKASYEIKKVWYGRTIIRSAYKLFYEAAQELLDGNLSVVDDIPEFKDLDEKSRQAKLEELVWAIGKLTDIARHVRAKRDGCGALELEGVEVCVQLDDKKNIHDLIPKQPLEVHETVAECMILANHWVAKKIWESFPHQALLRQHPPPHQEFFSELRECAKAKGFFIDTRSNKTLADSLDNANDPHDPIVNRLLRSMATQAMSNALYFSTGSCAEEEFHHYGLALDKYTHFTSPIRRYSDIVVHRLLMAAISKDKKMEIKGNLFSNKDLEELCRHINNRNQAAQHSQKQSTELFQCMYFKDKDPATEERCISDGVIYSIRTNGVLLFIPRFGIKGAAYLKNKDGLVISCGPDSCSEWKPGSLQRFQNKITSTTTDGESVTFHLFDHVTVRISIQASRCHSDTIRLEIISNKPYKIPNTELIHQSSPLLKSELVKEVTKSVEEAQLAQEVKVNIIQEEYQEYRQTKGRSLYTLLEEIRDLALLDVSNNYGI

Target ORF information:

RefSeq Version	NM_001323940.1
Organism	Homo sapiens(human)
Definition	Homo sapiens DIS3 like exosome 3'-5' exoribonuclease (DIS3L), transcript variant 7, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001323940.1

ORF Insert Sequence:

ATGACTGTGA CGACAAGGCT TCGGGCGAGT CCCCAAGTGA GCCCATGCCT ACAGGACTTC 
AGGGTGGTCG TGCGCATCGA TTCCTGGGAG TCAACATCTG TGTATCCAAA TGGACATTTT 
GTGCGTGTTT TAGGAAGAAT CGGAGATCTG GAAGGGGAAA TTGCAACCAT CCTGGTGGAA 
AACAGTATTT CAGTTATTCC TTTCTCAGAA GCTCAGATGT GTGAGATGCC AGTAAACACA 
CCAGAAAGTC CCTGGAAGGT GAGTCCTGAA GAGGAACAAA AACGTAAAGA CTTGAGGAAA 
AGCCATCTCG TATTCAGCAT TGACCCCAAA GGTTGTGAAG ATGTGGATGA CACACTCTCA 
GTCAGAACCT TAAATAATGG CAACCTGGAA CTTGGGGTCC ACATCGCAGA TGTAACACAC 
TTTGTGGCAC CAAATTCTTA CATTGATATT GAAGCTAGAA CAAGGGCCAC CACTTATTAT 
CTAGCAGATC GTCGCTATGA CATGCTGCCT TCCGTCCTCA GTGCAGATTT GTGTTCCCTT 
CTGGGAGGCG TTGATAGGTA TGCTGTAAGC ATCATGTGGG AACTGGATAA AGCCTCTTAT 
GAAATTAAGA AAGTGTGGTA TGGCAGAACC ATTATTCGAT CAGCATACAA ACTGTTCTAT 
GAAGCAGCCC AAGAACTACT GGATGGAAAC TTAAGCGTTG TTGATGATAT TCCAGAATTC 
AAAGACTTGG ATGAGAAGAG CAGACAAGCC AAGCTGGAGG AGTTGGTGTG GGCAATTGGA 
AAGCTGACCG ACATAGCTCG CCATGTCAGA GCTAAACGAG ACGGATGTGG TGCCCTGGAA 
CTGGAAGGGG TAGAGGTTTG CGTACAGCTA GATGACAAAA AGAACATTCA CGACCTCATC 
CCCAAGCAGC CCCTGGAAGT CCACGAGACA GTGGCTGAAT GCATGATCCT GGCCAACCAC 
TGGGTCGCCA AAAAGATCTG GGAGAGCTTC CCTCATCAGG CCTTGCTGCG CCAGCACCCT 
CCTCCACACC AGGAGTTCTT TTCAGAACTC CGGGAATGTG CTAAAGCCAA AGGCTTCTTC 
ATAGATACAC GGTCCAATAA AACACTGGCT GATTCTCTGG ATAATGCGAA CGACCCCCAC 
GATCCCATTG TGAACAGGCT ACTGCGCTCC ATGGCCACGC AGGCCATGTC GAATGCTCTG 
TACTTCTCCA CCGGATCCTG TGCGGAGGAG GAGTTCCATC ATTACGGTCT TGCATTAGAT 
AAATATACCC ACTTTACTTC TCCAATAAGA AGATATTCAG ATATTGTAGT ACACCGCTTG 
TTAATGGCAG CCATTTCAAA AGATAAGAAA ATGGAAATTA AGGGAAATCT GTTCAGCAAC 
AAAGATCTTG AGGAATTATG CAGACATATC AACAACAGAA ACCAAGCAGC ACAGCATTCT 
CAGAAGCAGT CTACTGAGCT CTTCCAGTGC ATGTACTTCA AAGACAAAGA CCCTGCCACC 
GAGGAGCGTT GCATATCTGA CGGAGTTATT TATTCAATTA GAACAAATGG TGTGCTTCTA 
TTTATACCAA GGTTTGGGAT TAAAGGTGCT GCTTATCTAA AAAATAAAGA TGGTTTAGTC 
ATCTCATGTG GCCCAGATAG CTGTTCTGAA TGGAAACCAG GATCCCTTCA ACGATTTCAA 
AACAAAATTA CCTCTACTAC AACAGATGGG GAATCTGTTA CGTTCCATTT GTTTGACCAT 
GTAACCGTAA GAATATCCAT ACAGGCCTCA CGTTGCCATT CTGATACAAT CAGACTTGAA 
ATAATTAGTA ACAAACCATA CAAGATACCA AATACAGAAC TTATTCATCA GAGTTCCCCC 
TTGCTGAAGA GTGAGTTAGT GAAAGAAGTA ACTAAATCTG TGGAAGAAGC TCAGCTTGCC 
CAAGAAGTCA AAGTAAACAT CATTCAGGAG GAATATCAAG AATATCGCCA AACAAAGGGA 
AGGAGCCTAT ACACACTTCT AGAGGAGATA CGGGACCTAG CTCTCCTGGA TGTTTCAAAC 
AATTATGGAA TATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

DIS3L ( NM_001323943.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_001310872.1 Homo sapiens DIS3 like exosome 3'-5' exoribonuclease (DIS3L), transcript variant 9, mRNA.

Price & Availability↑

CloneID	OHu82923
Clone ID Related Accession (Same CDS sequence)	NM_001323940.1 , NM_001323943.2 , NM_001323943.1 , NM_001323940.2
Accession Version	NM_001323943.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2055bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-09-27
Organism	Homo sapiens(human)
Product	DIS3-like exonuclease 1 isoform 4
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AC055855.9. On May 31, 2019 this sequence version replaced NM_001323943.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. ##Evidence-Data-START## Transcript exon combination :: SRR1803614.29892.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968968, SAMEA2142586 [ECO:0000348] ##Evidence-Data-END##

ATGACTGTGA CGACAAGGCT TCGGGCGAGT CCCCAAGTGA GCCCATGCCT ACAGGACTTC 
AGGGTGGTCG TGCGCATCGA TTCCTGGGAG TCAACATCTG TGTATCCAAA TGGACATTTT 
GTGCGTGTTT TAGGAAGAAT CGGAGATCTG GAAGGGGAAA TTGCAACCAT CCTGGTGGAA 
AACAGTATTT CAGTTATTCC TTTCTCAGAA GCTCAGATGT GTGAGATGCC AGTAAACACA 
CCAGAAAGTC CCTGGAAGGT GAGTCCTGAA GAGGAACAAA AACGTAAAGA CTTGAGGAAA 
AGCCATCTCG TATTCAGCAT TGACCCCAAA GGTTGTGAAG ATGTGGATGA CACACTCTCA 
GTCAGAACCT TAAATAATGG CAACCTGGAA CTTGGGGTCC ACATCGCAGA TGTAACACAC 
TTTGTGGCAC CAAATTCTTA CATTGATATT GAAGCTAGAA CAAGGGCCAC CACTTATTAT 
CTAGCAGATC GTCGCTATGA CATGCTGCCT TCCGTCCTCA GTGCAGATTT GTGTTCCCTT 
CTGGGAGGCG TTGATAGGTA TGCTGTAAGC ATCATGTGGG AACTGGATAA AGCCTCTTAT 
GAAATTAAGA AAGTGTGGTA TGGCAGAACC ATTATTCGAT CAGCATACAA ACTGTTCTAT 
GAAGCAGCCC AAGAACTACT GGATGGAAAC TTAAGCGTTG TTGATGATAT TCCAGAATTC 
AAAGACTTGG ATGAGAAGAG CAGACAAGCC AAGCTGGAGG AGTTGGTGTG GGCAATTGGA 
AAGCTGACCG ACATAGCTCG CCATGTCAGA GCTAAACGAG ACGGATGTGG TGCCCTGGAA 
CTGGAAGGGG TAGAGGTTTG CGTACAGCTA GATGACAAAA AGAACATTCA CGACCTCATC 
CCCAAGCAGC CCCTGGAAGT CCACGAGACA GTGGCTGAAT GCATGATCCT GGCCAACCAC 
TGGGTCGCCA AAAAGATCTG GGAGAGCTTC CCTCATCAGG CCTTGCTGCG CCAGCACCCT 
CCTCCACACC AGGAGTTCTT TTCAGAACTC CGGGAATGTG CTAAAGCCAA AGGCTTCTTC 
ATAGATACAC GGTCCAATAA AACACTGGCT GATTCTCTGG ATAATGCGAA CGACCCCCAC 
GATCCCATTG TGAACAGGCT ACTGCGCTCC ATGGCCACGC AGGCCATGTC GAATGCTCTG 
TACTTCTCCA CCGGATCCTG TGCGGAGGAG GAGTTCCATC ATTACGGTCT TGCATTAGAT 
AAATATACCC ACTTTACTTC TCCAATAAGA AGATATTCAG ATATTGTAGT ACACCGCTTG 
TTAATGGCAG CCATTTCAAA AGATAAGAAA ATGGAAATTA AGGGAAATCT GTTCAGCAAC 
AAAGATCTTG AGGAATTATG CAGACATATC AACAACAGAA ACCAAGCAGC ACAGCATTCT 
CAGAAGCAGT CTACTGAGCT CTTCCAGTGC ATGTACTTCA AAGACAAAGA CCCTGCCACC 
GAGGAGCGTT GCATATCTGA CGGAGTTATT TATTCAATTA GAACAAATGG TGTGCTTCTA 
TTTATACCAA GGTTTGGGAT TAAAGGTGCT GCTTATCTAA AAAATAAAGA TGGTTTAGTC 
ATCTCATGTG GCCCAGATAG CTGTTCTGAA TGGAAACCAG GATCCCTTCA ACGATTTCAA 
AACAAAATTA CCTCTACTAC AACAGATGGG GAATCTGTTA CGTTCCATTT GTTTGACCAT 
GTAACCGTAA GAATATCCAT ACAGGCCTCA CGTTGCCATT CTGATACAAT CAGACTTGAA 
ATAATTAGTA ACAAACCATA CAAGATACCA AATACAGAAC TTATTCATCA GAGTTCCCCC 
TTGCTGAAGA GTGAGTTAGT GAAAGAAGTA ACTAAATCTG TGGAAGAAGC TCAGCTTGCC 
CAAGAAGTCA AAGTAAACAT CATTCAGGAG GAATATCAAG AATATCGCCA AACAAAGGGA 
AGGAGCCTAT ACACACTTCT AGAGGAGATA CGGGACCTAG CTCTCCTGGA TGTTTCAAAC 
AATTATGGAA TATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001310872.1
CDS	1162..3216
Translation	MTVTTRLRASPQVSPCLQDFRVVVRIDSWESTSVYPNGHFVRVLGRIGDLEGEIATILVENSISVIPFSEAQMCEMPVNTPESPWKVSPEEEQKRKDLRKSHLVFSIDPKGCEDVDDTLSVRTLNNGNLELGVHIADVTHFVAPNSYIDIEARTRATTYYLADRRYDMLPSVLSADLCSLLGGVDRYAVSIMWELDKASYEIKKVWYGRTIIRSAYKLFYEAAQELLDGNLSVVDDIPEFKDLDEKSRQAKLEELVWAIGKLTDIARHVRAKRDGCGALELEGVEVCVQLDDKKNIHDLIPKQPLEVHETVAECMILANHWVAKKIWESFPHQALLRQHPPPHQEFFSELRECAKAKGFFIDTRSNKTLADSLDNANDPHDPIVNRLLRSMATQAMSNALYFSTGSCAEEEFHHYGLALDKYTHFTSPIRRYSDIVVHRLLMAAISKDKKMEIKGNLFSNKDLEELCRHINNRNQAAQHSQKQSTELFQCMYFKDKDPATEERCISDGVIYSIRTNGVLLFIPRFGIKGAAYLKNKDGLVISCGPDSCSEWKPGSLQRFQNKITSTTTDGESVTFHLFDHVTVRISIQASRCHSDTIRLEIISNKPYKIPNTELIHQSSPLLKSELVKEVTKSVEEAQLAQEVKVNIIQEEYQEYRQTKGRSLYTLLEEIRDLALLDVSNNYGI

Target ORF information:

RefSeq Version	NM_001323943.2
Organism	Homo sapiens(human)
Definition	Homo sapiens DIS3 like exosome 3'-5' exoribonuclease (DIS3L), transcript variant 9, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001323943.2

ORF Insert Sequence:

ATGACTGTGA CGACAAGGCT TCGGGCGAGT CCCCAAGTGA GCCCATGCCT ACAGGACTTC 
AGGGTGGTCG TGCGCATCGA TTCCTGGGAG TCAACATCTG TGTATCCAAA TGGACATTTT 
GTGCGTGTTT TAGGAAGAAT CGGAGATCTG GAAGGGGAAA TTGCAACCAT CCTGGTGGAA 
AACAGTATTT CAGTTATTCC TTTCTCAGAA GCTCAGATGT GTGAGATGCC AGTAAACACA 
CCAGAAAGTC CCTGGAAGGT GAGTCCTGAA GAGGAACAAA AACGTAAAGA CTTGAGGAAA 
AGCCATCTCG TATTCAGCAT TGACCCCAAA GGTTGTGAAG ATGTGGATGA CACACTCTCA 
GTCAGAACCT TAAATAATGG CAACCTGGAA CTTGGGGTCC ACATCGCAGA TGTAACACAC 
TTTGTGGCAC CAAATTCTTA CATTGATATT GAAGCTAGAA CAAGGGCCAC CACTTATTAT 
CTAGCAGATC GTCGCTATGA CATGCTGCCT TCCGTCCTCA GTGCAGATTT GTGTTCCCTT 
CTGGGAGGCG TTGATAGGTA TGCTGTAAGC ATCATGTGGG AACTGGATAA AGCCTCTTAT 
GAAATTAAGA AAGTGTGGTA TGGCAGAACC ATTATTCGAT CAGCATACAA ACTGTTCTAT 
GAAGCAGCCC AAGAACTACT GGATGGAAAC TTAAGCGTTG TTGATGATAT TCCAGAATTC 
AAAGACTTGG ATGAGAAGAG CAGACAAGCC AAGCTGGAGG AGTTGGTGTG GGCAATTGGA 
AAGCTGACCG ACATAGCTCG CCATGTCAGA GCTAAACGAG ACGGATGTGG TGCCCTGGAA 
CTGGAAGGGG TAGAGGTTTG CGTACAGCTA GATGACAAAA AGAACATTCA CGACCTCATC 
CCCAAGCAGC CCCTGGAAGT CCACGAGACA GTGGCTGAAT GCATGATCCT GGCCAACCAC 
TGGGTCGCCA AAAAGATCTG GGAGAGCTTC CCTCATCAGG CCTTGCTGCG CCAGCACCCT 
CCTCCACACC AGGAGTTCTT TTCAGAACTC CGGGAATGTG CTAAAGCCAA AGGCTTCTTC 
ATAGATACAC GGTCCAATAA AACACTGGCT GATTCTCTGG ATAATGCGAA CGACCCCCAC 
GATCCCATTG TGAACAGGCT ACTGCGCTCC ATGGCCACGC AGGCCATGTC GAATGCTCTG 
TACTTCTCCA CCGGATCCTG TGCGGAGGAG GAGTTCCATC ATTACGGTCT TGCATTAGAT 
AAATATACCC ACTTTACTTC TCCAATAAGA AGATATTCAG ATATTGTAGT ACACCGCTTG 
TTAATGGCAG CCATTTCAAA AGATAAGAAA ATGGAAATTA AGGGAAATCT GTTCAGCAAC 
AAAGATCTTG AGGAATTATG CAGACATATC AACAACAGAA ACCAAGCAGC ACAGCATTCT 
CAGAAGCAGT CTACTGAGCT CTTCCAGTGC ATGTACTTCA AAGACAAAGA CCCTGCCACC 
GAGGAGCGTT GCATATCTGA CGGAGTTATT TATTCAATTA GAACAAATGG TGTGCTTCTA 
TTTATACCAA GGTTTGGGAT TAAAGGTGCT GCTTATCTAA AAAATAAAGA TGGTTTAGTC 
ATCTCATGTG GCCCAGATAG CTGTTCTGAA TGGAAACCAG GATCCCTTCA ACGATTTCAA 
AACAAAATTA CCTCTACTAC AACAGATGGG GAATCTGTTA CGTTCCATTT GTTTGACCAT 
GTAACCGTAA GAATATCCAT ACAGGCCTCA CGTTGCCATT CTGATACAAT CAGACTTGAA 
ATAATTAGTA ACAAACCATA CAAGATACCA AATACAGAAC TTATTCATCA GAGTTCCCCC 
TTGCTGAAGA GTGAGTTAGT GAAAGAAGTA ACTAAATCTG TGGAAGAAGC TCAGCTTGCC 
CAAGAAGTCA AAGTAAACAT CATTCAGGAG GAATATCAAG AATATCGCCA AACAAAGGGA 
AGGAGCCTAT ACACACTTCT AGAGGAGATA CGGGACCTAG CTCTCCTGGA TGTTTCAAAC 
AATTATGGAA TATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

DIS3L ( NM_001323943.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001310872.1 Homo sapiens DIS3 like exosome 3'-5' exoribonuclease (DIS3L), transcript variant 9, mRNA.

Price & Availability↑

CloneID	OHu82923
Clone ID Related Accession (Same CDS sequence)	NM_001323940.1 , NM_001323943.2 , NM_001323943.1 , NM_001323940.2
Accession Version	NM_001323943.1	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2055bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2018-12-04
Organism	Homo sapiens(human)
Product	DIS3-like exonuclease 1 isoform 4
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AC055855.9. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. ##Evidence-Data-START## Transcript exon combination :: SRR1803614.29892.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968968, SAMEA2142586 [ECO:0000348] ##Evidence-Data-END##

ATGACTGTGA CGACAAGGCT TCGGGCGAGT CCCCAAGTGA GCCCATGCCT ACAGGACTTC 
AGGGTGGTCG TGCGCATCGA TTCCTGGGAG TCAACATCTG TGTATCCAAA TGGACATTTT 
GTGCGTGTTT TAGGAAGAAT CGGAGATCTG GAAGGGGAAA TTGCAACCAT CCTGGTGGAA 
AACAGTATTT CAGTTATTCC TTTCTCAGAA GCTCAGATGT GTGAGATGCC AGTAAACACA 
CCAGAAAGTC CCTGGAAGGT GAGTCCTGAA GAGGAACAAA AACGTAAAGA CTTGAGGAAA 
AGCCATCTCG TATTCAGCAT TGACCCCAAA GGTTGTGAAG ATGTGGATGA CACACTCTCA 
GTCAGAACCT TAAATAATGG CAACCTGGAA CTTGGGGTCC ACATCGCAGA TGTAACACAC 
TTTGTGGCAC CAAATTCTTA CATTGATATT GAAGCTAGAA CAAGGGCCAC CACTTATTAT 
CTAGCAGATC GTCGCTATGA CATGCTGCCT TCCGTCCTCA GTGCAGATTT GTGTTCCCTT 
CTGGGAGGCG TTGATAGGTA TGCTGTAAGC ATCATGTGGG AACTGGATAA AGCCTCTTAT 
GAAATTAAGA AAGTGTGGTA TGGCAGAACC ATTATTCGAT CAGCATACAA ACTGTTCTAT 
GAAGCAGCCC AAGAACTACT GGATGGAAAC TTAAGCGTTG TTGATGATAT TCCAGAATTC 
AAAGACTTGG ATGAGAAGAG CAGACAAGCC AAGCTGGAGG AGTTGGTGTG GGCAATTGGA 
AAGCTGACCG ACATAGCTCG CCATGTCAGA GCTAAACGAG ACGGATGTGG TGCCCTGGAA 
CTGGAAGGGG TAGAGGTTTG CGTACAGCTA GATGACAAAA AGAACATTCA CGACCTCATC 
CCCAAGCAGC CCCTGGAAGT CCACGAGACA GTGGCTGAAT GCATGATCCT GGCCAACCAC 
TGGGTCGCCA AAAAGATCTG GGAGAGCTTC CCTCATCAGG CCTTGCTGCG CCAGCACCCT 
CCTCCACACC AGGAGTTCTT TTCAGAACTC CGGGAATGTG CTAAAGCCAA AGGCTTCTTC 
ATAGATACAC GGTCCAATAA AACACTGGCT GATTCTCTGG ATAATGCGAA CGACCCCCAC 
GATCCCATTG TGAACAGGCT ACTGCGCTCC ATGGCCACGC AGGCCATGTC GAATGCTCTG 
TACTTCTCCA CCGGATCCTG TGCGGAGGAG GAGTTCCATC ATTACGGTCT TGCATTAGAT 
AAATATACCC ACTTTACTTC TCCAATAAGA AGATATTCAG ATATTGTAGT ACACCGCTTG 
TTAATGGCAG CCATTTCAAA AGATAAGAAA ATGGAAATTA AGGGAAATCT GTTCAGCAAC 
AAAGATCTTG AGGAATTATG CAGACATATC AACAACAGAA ACCAAGCAGC ACAGCATTCT 
CAGAAGCAGT CTACTGAGCT CTTCCAGTGC ATGTACTTCA AAGACAAAGA CCCTGCCACC 
GAGGAGCGTT GCATATCTGA CGGAGTTATT TATTCAATTA GAACAAATGG TGTGCTTCTA 
TTTATACCAA GGTTTGGGAT TAAAGGTGCT GCTTATCTAA AAAATAAAGA TGGTTTAGTC 
ATCTCATGTG GCCCAGATAG CTGTTCTGAA TGGAAACCAG GATCCCTTCA ACGATTTCAA 
AACAAAATTA CCTCTACTAC AACAGATGGG GAATCTGTTA CGTTCCATTT GTTTGACCAT 
GTAACCGTAA GAATATCCAT ACAGGCCTCA CGTTGCCATT CTGATACAAT CAGACTTGAA 
ATAATTAGTA ACAAACCATA CAAGATACCA AATACAGAAC TTATTCATCA GAGTTCCCCC 
TTGCTGAAGA GTGAGTTAGT GAAAGAAGTA ACTAAATCTG TGGAAGAAGC TCAGCTTGCC 
CAAGAAGTCA AAGTAAACAT CATTCAGGAG GAATATCAAG AATATCGCCA AACAAAGGGA 
AGGAGCCTAT ACACACTTCT AGAGGAGATA CGGGACCTAG CTCTCCTGGA TGTTTCAAAC 
AATTATGGAA TATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001310872.1
CDS	1157..3211
Translation	MTVTTRLRASPQVSPCLQDFRVVVRIDSWESTSVYPNGHFVRVLGRIGDLEGEIATILVENSISVIPFSEAQMCEMPVNTPESPWKVSPEEEQKRKDLRKSHLVFSIDPKGCEDVDDTLSVRTLNNGNLELGVHIADVTHFVAPNSYIDIEARTRATTYYLADRRYDMLPSVLSADLCSLLGGVDRYAVSIMWELDKASYEIKKVWYGRTIIRSAYKLFYEAAQELLDGNLSVVDDIPEFKDLDEKSRQAKLEELVWAIGKLTDIARHVRAKRDGCGALELEGVEVCVQLDDKKNIHDLIPKQPLEVHETVAECMILANHWVAKKIWESFPHQALLRQHPPPHQEFFSELRECAKAKGFFIDTRSNKTLADSLDNANDPHDPIVNRLLRSMATQAMSNALYFSTGSCAEEEFHHYGLALDKYTHFTSPIRRYSDIVVHRLLMAAISKDKKMEIKGNLFSNKDLEELCRHINNRNQAAQHSQKQSTELFQCMYFKDKDPATEERCISDGVIYSIRTNGVLLFIPRFGIKGAAYLKNKDGLVISCGPDSCSEWKPGSLQRFQNKITSTTTDGESVTFHLFDHVTVRISIQASRCHSDTIRLEIISNKPYKIPNTELIHQSSPLLKSELVKEVTKSVEEAQLAQEVKVNIIQEEYQEYRQTKGRSLYTLLEEIRDLALLDVSNNYGI

Target ORF information:

RefSeq Version	NM_001323943.1
Organism	Homo sapiens(human)
Definition	Homo sapiens DIS3 like exosome 3'-5' exoribonuclease (DIS3L), transcript variant 9, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001323943.1

ORF Insert Sequence:

ATGACTGTGA CGACAAGGCT TCGGGCGAGT CCCCAAGTGA GCCCATGCCT ACAGGACTTC 
AGGGTGGTCG TGCGCATCGA TTCCTGGGAG TCAACATCTG TGTATCCAAA TGGACATTTT 
GTGCGTGTTT TAGGAAGAAT CGGAGATCTG GAAGGGGAAA TTGCAACCAT CCTGGTGGAA 
AACAGTATTT CAGTTATTCC TTTCTCAGAA GCTCAGATGT GTGAGATGCC AGTAAACACA 
CCAGAAAGTC CCTGGAAGGT GAGTCCTGAA GAGGAACAAA AACGTAAAGA CTTGAGGAAA 
AGCCATCTCG TATTCAGCAT TGACCCCAAA GGTTGTGAAG ATGTGGATGA CACACTCTCA 
GTCAGAACCT TAAATAATGG CAACCTGGAA CTTGGGGTCC ACATCGCAGA TGTAACACAC 
TTTGTGGCAC CAAATTCTTA CATTGATATT GAAGCTAGAA CAAGGGCCAC CACTTATTAT 
CTAGCAGATC GTCGCTATGA CATGCTGCCT TCCGTCCTCA GTGCAGATTT GTGTTCCCTT 
CTGGGAGGCG TTGATAGGTA TGCTGTAAGC ATCATGTGGG AACTGGATAA AGCCTCTTAT 
GAAATTAAGA AAGTGTGGTA TGGCAGAACC ATTATTCGAT CAGCATACAA ACTGTTCTAT 
GAAGCAGCCC AAGAACTACT GGATGGAAAC TTAAGCGTTG TTGATGATAT TCCAGAATTC 
AAAGACTTGG ATGAGAAGAG CAGACAAGCC AAGCTGGAGG AGTTGGTGTG GGCAATTGGA 
AAGCTGACCG ACATAGCTCG CCATGTCAGA GCTAAACGAG ACGGATGTGG TGCCCTGGAA 
CTGGAAGGGG TAGAGGTTTG CGTACAGCTA GATGACAAAA AGAACATTCA CGACCTCATC 
CCCAAGCAGC CCCTGGAAGT CCACGAGACA GTGGCTGAAT GCATGATCCT GGCCAACCAC 
TGGGTCGCCA AAAAGATCTG GGAGAGCTTC CCTCATCAGG CCTTGCTGCG CCAGCACCCT 
CCTCCACACC AGGAGTTCTT TTCAGAACTC CGGGAATGTG CTAAAGCCAA AGGCTTCTTC 
ATAGATACAC GGTCCAATAA AACACTGGCT GATTCTCTGG ATAATGCGAA CGACCCCCAC 
GATCCCATTG TGAACAGGCT ACTGCGCTCC ATGGCCACGC AGGCCATGTC GAATGCTCTG 
TACTTCTCCA CCGGATCCTG TGCGGAGGAG GAGTTCCATC ATTACGGTCT TGCATTAGAT 
AAATATACCC ACTTTACTTC TCCAATAAGA AGATATTCAG ATATTGTAGT ACACCGCTTG 
TTAATGGCAG CCATTTCAAA AGATAAGAAA ATGGAAATTA AGGGAAATCT GTTCAGCAAC 
AAAGATCTTG AGGAATTATG CAGACATATC AACAACAGAA ACCAAGCAGC ACAGCATTCT 
CAGAAGCAGT CTACTGAGCT CTTCCAGTGC ATGTACTTCA AAGACAAAGA CCCTGCCACC 
GAGGAGCGTT GCATATCTGA CGGAGTTATT TATTCAATTA GAACAAATGG TGTGCTTCTA 
TTTATACCAA GGTTTGGGAT TAAAGGTGCT GCTTATCTAA AAAATAAAGA TGGTTTAGTC 
ATCTCATGTG GCCCAGATAG CTGTTCTGAA TGGAAACCAG GATCCCTTCA ACGATTTCAA 
AACAAAATTA CCTCTACTAC AACAGATGGG GAATCTGTTA CGTTCCATTT GTTTGACCAT 
GTAACCGTAA GAATATCCAT ACAGGCCTCA CGTTGCCATT CTGATACAAT CAGACTTGAA 
ATAATTAGTA ACAAACCATA CAAGATACCA AATACAGAAC TTATTCATCA GAGTTCCCCC 
TTGCTGAAGA GTGAGTTAGT GAAAGAAGTA ACTAAATCTG TGGAAGAAGC TCAGCTTGCC 
CAAGAAGTCA AAGTAAACAT CATTCAGGAG GAATATCAAG AATATCGCCA AACAAAGGGA 
AGGAGCCTAT ACACACTTCT AGAGGAGATA CGGGACCTAG CTCTCCTGGA TGTTTCAAAC 
AATTATGGAA TATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

DIS3L ( NM_001323940.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_001310869.1 Homo sapiens DIS3 like exosome 3'-5' exoribonuclease (DIS3L), transcript variant 7, mRNA.

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CloneID	OHu82923
Clone ID Related Accession (Same CDS sequence)	NM_001323940.1 , NM_001323943.2 , NM_001323943.1 , NM_001323940.2
Accession Version	NM_001323940.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2055bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-09-27
Organism	Homo sapiens(human)
Product	DIS3-like exonuclease 1 isoform 4
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AC055855.9. On May 31, 2019 this sequence version replaced NM_001323940.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. ##Evidence-Data-START## Transcript exon combination :: SRR1803616.243516.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968968, SAMEA2142586 [ECO:0000348] ##Evidence-Data-END##

ATGACTGTGA CGACAAGGCT TCGGGCGAGT CCCCAAGTGA GCCCATGCCT ACAGGACTTC 
AGGGTGGTCG TGCGCATCGA TTCCTGGGAG TCAACATCTG TGTATCCAAA TGGACATTTT 
GTGCGTGTTT TAGGAAGAAT CGGAGATCTG GAAGGGGAAA TTGCAACCAT CCTGGTGGAA 
AACAGTATTT CAGTTATTCC TTTCTCAGAA GCTCAGATGT GTGAGATGCC AGTAAACACA 
CCAGAAAGTC CCTGGAAGGT GAGTCCTGAA GAGGAACAAA AACGTAAAGA CTTGAGGAAA 
AGCCATCTCG TATTCAGCAT TGACCCCAAA GGTTGTGAAG ATGTGGATGA CACACTCTCA 
GTCAGAACCT TAAATAATGG CAACCTGGAA CTTGGGGTCC ACATCGCAGA TGTAACACAC 
TTTGTGGCAC CAAATTCTTA CATTGATATT GAAGCTAGAA CAAGGGCCAC CACTTATTAT 
CTAGCAGATC GTCGCTATGA CATGCTGCCT TCCGTCCTCA GTGCAGATTT GTGTTCCCTT 
CTGGGAGGCG TTGATAGGTA TGCTGTAAGC ATCATGTGGG AACTGGATAA AGCCTCTTAT 
GAAATTAAGA AAGTGTGGTA TGGCAGAACC ATTATTCGAT CAGCATACAA ACTGTTCTAT 
GAAGCAGCCC AAGAACTACT GGATGGAAAC TTAAGCGTTG TTGATGATAT TCCAGAATTC 
AAAGACTTGG ATGAGAAGAG CAGACAAGCC AAGCTGGAGG AGTTGGTGTG GGCAATTGGA 
AAGCTGACCG ACATAGCTCG CCATGTCAGA GCTAAACGAG ACGGATGTGG TGCCCTGGAA 
CTGGAAGGGG TAGAGGTTTG CGTACAGCTA GATGACAAAA AGAACATTCA CGACCTCATC 
CCCAAGCAGC CCCTGGAAGT CCACGAGACA GTGGCTGAAT GCATGATCCT GGCCAACCAC 
TGGGTCGCCA AAAAGATCTG GGAGAGCTTC CCTCATCAGG CCTTGCTGCG CCAGCACCCT 
CCTCCACACC AGGAGTTCTT TTCAGAACTC CGGGAATGTG CTAAAGCCAA AGGCTTCTTC 
ATAGATACAC GGTCCAATAA AACACTGGCT GATTCTCTGG ATAATGCGAA CGACCCCCAC 
GATCCCATTG TGAACAGGCT ACTGCGCTCC ATGGCCACGC AGGCCATGTC GAATGCTCTG 
TACTTCTCCA CCGGATCCTG TGCGGAGGAG GAGTTCCATC ATTACGGTCT TGCATTAGAT 
AAATATACCC ACTTTACTTC TCCAATAAGA AGATATTCAG ATATTGTAGT ACACCGCTTG 
TTAATGGCAG CCATTTCAAA AGATAAGAAA ATGGAAATTA AGGGAAATCT GTTCAGCAAC 
AAAGATCTTG AGGAATTATG CAGACATATC AACAACAGAA ACCAAGCAGC ACAGCATTCT 
CAGAAGCAGT CTACTGAGCT CTTCCAGTGC ATGTACTTCA AAGACAAAGA CCCTGCCACC 
GAGGAGCGTT GCATATCTGA CGGAGTTATT TATTCAATTA GAACAAATGG TGTGCTTCTA 
TTTATACCAA GGTTTGGGAT TAAAGGTGCT GCTTATCTAA AAAATAAAGA TGGTTTAGTC 
ATCTCATGTG GCCCAGATAG CTGTTCTGAA TGGAAACCAG GATCCCTTCA ACGATTTCAA 
AACAAAATTA CCTCTACTAC AACAGATGGG GAATCTGTTA CGTTCCATTT GTTTGACCAT 
GTAACCGTAA GAATATCCAT ACAGGCCTCA CGTTGCCATT CTGATACAAT CAGACTTGAA 
ATAATTAGTA ACAAACCATA CAAGATACCA AATACAGAAC TTATTCATCA GAGTTCCCCC 
TTGCTGAAGA GTGAGTTAGT GAAAGAAGTA ACTAAATCTG TGGAAGAAGC TCAGCTTGCC 
CAAGAAGTCA AAGTAAACAT CATTCAGGAG GAATATCAAG AATATCGCCA AACAAAGGGA 
AGGAGCCTAT ACACACTTCT AGAGGAGATA CGGGACCTAG CTCTCCTGGA TGTTTCAAAC 
AATTATGGAA TATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001310869.1
CDS	970..3024
Translation	MTVTTRLRASPQVSPCLQDFRVVVRIDSWESTSVYPNGHFVRVLGRIGDLEGEIATILVENSISVIPFSEAQMCEMPVNTPESPWKVSPEEEQKRKDLRKSHLVFSIDPKGCEDVDDTLSVRTLNNGNLELGVHIADVTHFVAPNSYIDIEARTRATTYYLADRRYDMLPSVLSADLCSLLGGVDRYAVSIMWELDKASYEIKKVWYGRTIIRSAYKLFYEAAQELLDGNLSVVDDIPEFKDLDEKSRQAKLEELVWAIGKLTDIARHVRAKRDGCGALELEGVEVCVQLDDKKNIHDLIPKQPLEVHETVAECMILANHWVAKKIWESFPHQALLRQHPPPHQEFFSELRECAKAKGFFIDTRSNKTLADSLDNANDPHDPIVNRLLRSMATQAMSNALYFSTGSCAEEEFHHYGLALDKYTHFTSPIRRYSDIVVHRLLMAAISKDKKMEIKGNLFSNKDLEELCRHINNRNQAAQHSQKQSTELFQCMYFKDKDPATEERCISDGVIYSIRTNGVLLFIPRFGIKGAAYLKNKDGLVISCGPDSCSEWKPGSLQRFQNKITSTTTDGESVTFHLFDHVTVRISIQASRCHSDTIRLEIISNKPYKIPNTELIHQSSPLLKSELVKEVTKSVEEAQLAQEVKVNIIQEEYQEYRQTKGRSLYTLLEEIRDLALLDVSNNYGI

Target ORF information:

RefSeq Version	NM_001323940.2
Organism	Homo sapiens(human)
Definition	Homo sapiens DIS3 like exosome 3'-5' exoribonuclease (DIS3L), transcript variant 7, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001323940.2

ORF Insert Sequence:

ATGACTGTGA CGACAAGGCT TCGGGCGAGT CCCCAAGTGA GCCCATGCCT ACAGGACTTC 
AGGGTGGTCG TGCGCATCGA TTCCTGGGAG TCAACATCTG TGTATCCAAA TGGACATTTT 
GTGCGTGTTT TAGGAAGAAT CGGAGATCTG GAAGGGGAAA TTGCAACCAT CCTGGTGGAA 
AACAGTATTT CAGTTATTCC TTTCTCAGAA GCTCAGATGT GTGAGATGCC AGTAAACACA 
CCAGAAAGTC CCTGGAAGGT GAGTCCTGAA GAGGAACAAA AACGTAAAGA CTTGAGGAAA 
AGCCATCTCG TATTCAGCAT TGACCCCAAA GGTTGTGAAG ATGTGGATGA CACACTCTCA 
GTCAGAACCT TAAATAATGG CAACCTGGAA CTTGGGGTCC ACATCGCAGA TGTAACACAC 
TTTGTGGCAC CAAATTCTTA CATTGATATT GAAGCTAGAA CAAGGGCCAC CACTTATTAT 
CTAGCAGATC GTCGCTATGA CATGCTGCCT TCCGTCCTCA GTGCAGATTT GTGTTCCCTT 
CTGGGAGGCG TTGATAGGTA TGCTGTAAGC ATCATGTGGG AACTGGATAA AGCCTCTTAT 
GAAATTAAGA AAGTGTGGTA TGGCAGAACC ATTATTCGAT CAGCATACAA ACTGTTCTAT 
GAAGCAGCCC AAGAACTACT GGATGGAAAC TTAAGCGTTG TTGATGATAT TCCAGAATTC 
AAAGACTTGG ATGAGAAGAG CAGACAAGCC AAGCTGGAGG AGTTGGTGTG GGCAATTGGA 
AAGCTGACCG ACATAGCTCG CCATGTCAGA GCTAAACGAG ACGGATGTGG TGCCCTGGAA 
CTGGAAGGGG TAGAGGTTTG CGTACAGCTA GATGACAAAA AGAACATTCA CGACCTCATC 
CCCAAGCAGC CCCTGGAAGT CCACGAGACA GTGGCTGAAT GCATGATCCT GGCCAACCAC 
TGGGTCGCCA AAAAGATCTG GGAGAGCTTC CCTCATCAGG CCTTGCTGCG CCAGCACCCT 
CCTCCACACC AGGAGTTCTT TTCAGAACTC CGGGAATGTG CTAAAGCCAA AGGCTTCTTC 
ATAGATACAC GGTCCAATAA AACACTGGCT GATTCTCTGG ATAATGCGAA CGACCCCCAC 
GATCCCATTG TGAACAGGCT ACTGCGCTCC ATGGCCACGC AGGCCATGTC GAATGCTCTG 
TACTTCTCCA CCGGATCCTG TGCGGAGGAG GAGTTCCATC ATTACGGTCT TGCATTAGAT 
AAATATACCC ACTTTACTTC TCCAATAAGA AGATATTCAG ATATTGTAGT ACACCGCTTG 
TTAATGGCAG CCATTTCAAA AGATAAGAAA ATGGAAATTA AGGGAAATCT GTTCAGCAAC 
AAAGATCTTG AGGAATTATG CAGACATATC AACAACAGAA ACCAAGCAGC ACAGCATTCT 
CAGAAGCAGT CTACTGAGCT CTTCCAGTGC ATGTACTTCA AAGACAAAGA CCCTGCCACC 
GAGGAGCGTT GCATATCTGA CGGAGTTATT TATTCAATTA GAACAAATGG TGTGCTTCTA 
TTTATACCAA GGTTTGGGAT TAAAGGTGCT GCTTATCTAA AAAATAAAGA TGGTTTAGTC 
ATCTCATGTG GCCCAGATAG CTGTTCTGAA TGGAAACCAG GATCCCTTCA ACGATTTCAA 
AACAAAATTA CCTCTACTAC AACAGATGGG GAATCTGTTA CGTTCCATTT GTTTGACCAT 
GTAACCGTAA GAATATCCAT ACAGGCCTCA CGTTGCCATT CTGATACAAT CAGACTTGAA 
ATAATTAGTA ACAAACCATA CAAGATACCA AATACAGAAC TTATTCATCA GAGTTCCCCC 
TTGCTGAAGA GTGAGTTAGT GAAAGAAGTA ACTAAATCTG TGGAAGAAGC TCAGCTTGCC 
CAAGAAGTCA AAGTAAACAT CATTCAGGAG GAATATCAAG AATATCGCCA AACAAAGGGA 
AGGAGCCTAT ACACACTTCT AGAGGAGATA CGGGACCTAG CTCTCCTGGA TGTTTCAAAC 
AATTATGGAA TATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

DIS3L ( NM_001323944.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001310873.1 Homo sapiens DIS3 like exosome 3'-5' exoribonuclease (DIS3L), transcript variant 10, mRNA.

Price & Availability↑

CloneID	OHu48094
Clone ID Related Accession (Same CDS sequence)	NM_001323944.1 , NM_001323944.2
Accession Version	NM_001323944.1	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 3114bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2018-12-04
Organism	Homo sapiens(human)
Product	DIS3-like exonuclease 1 isoform 6
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AC055855.9. On Apr 23, 2016 this sequence version replaced XM_005254144.2. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. ##Evidence-Data-START## Transcript exon combination :: SRR1660805.41990.1, SRR1803613.45024.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END##

ATGGGGAGGT CCCGAGCTGG GAGCCCCCGG GAGCTACAGG CCAGCTGCTG CCGCTGCGAA 
GCTGACATCG CCTGCTTTGC AGCCACAGAT GGGAAACTCT TGTCTAGTGA TGTGACTCAT 
TACGTGATCC CAGACTGGAA AGTTGTTCAA GATTATCTTG AGATCCTTGA GTTTCCTGAG 
TTGAAGGGAA TTATTTTCAT GCAGACAGCT TGTCAAGCTG TGCAGCATCA AAGAGGCAGG 
AGACAGTATA ACAAACTGCG AAACCTGCTG AAGGATGCGC GTCATGATTG CATTCTCTTT 
GCTAATGAAT TCCAGCAATG CTGCTATCTG CCACGGGAAA GAGGAGAGTC CATGGAGAAG 
TGGCAGACCA GGAGCATATA CAACGCAGCT GTTTGGTACT ATCATCACTG CCAGGACAGG 
ATGCCAATTG TTATGGTGAC AGAAGATGAA GAGGCAATTC AGCAGTATGG AAGTGAAACA 
GAAGGAGTAT TCGTGATTAC TTTCAAGAAT TACCTGGACA ATTTCTGGCC TGATTTAAAA 
GCTGCCCACG AGCTTTGTGA TTCTATCCTT CAGTCTCGAC GGGAGAGAGA GAATGAGAGT 
CAGGAGAGCC ATGGGAAGGA GTACCCAGAA CATCTTCCCC TGGAAGTGTT AGAAGCTGGG 
ATTAAATCTG GACGCTATAT CCAGGGAATT CTGAATGTCA ACAAACACAG AGCCCAAATA 
GAAGCTTTTG TTCGACTTCA AGGAGCCAGC AGTAAAGATT CAGATTTAGT CAGTGACATC 
CTAATCCACG GGATGAAGGC TCGAAACCGC TCAATTCATG GAGATGTGGT AGTTGTGGAG 
CTGCTTCCTA AAAATGAATG GAAAGGAAGA ACCGTAGCCC TGTGTGAGAA TGACTGTGAC 
GACAAGGCTT CGGGCGAGTC CCCAAGTGAG CCCATGCCTA CAGGTCGAGT GGTGGGCATA 
CTTCAGAAGA ACTGGCGGGA TTATGTGGTG ACATTTCCGT CCAAAGAAGA GGTCCAATCT 
CAGGGCAAAA ATGCTCAGAA AATCCTGGTT ACACCTTGGG ATTACAGAAT TCCCAAAATT 
CGAATTAGCA CTCAGCAAGC AGAAACCCTC CAGGACTTCA GGGTGGTCGT GCGCATCGAT 
TCCTGGGAGT CAACATCTGT GTATCCAAAT GGACATTTTG TGCGTGTTTT AGGAAGAATC 
GGAGATCTGG AAGGGGAAAT TGCAACCATC CTGGTGGAAA ACAGTATTTC AGTTATTCCT 
TTCTCAGAAG CTCAGATGTG TGAGATGCCA GTAAACACAC CAGAAAGTCC CTGGAAGGTG 
AGTCCTGAAG AGGAACAAAA ACGTAAAGAC TTGAGGAAAA GCCATCTCGT ATTCAGCATT 
GACCCCAAAG GTTGTGAAGA TGTGGATGAC ACACTCTCAG TCAGAACCTT AAATAATGGC 
AACCTGGAAC TTGGGGTCCA CATCGCAGAT GTAACACACT TTGTGGCACC AAATTCTTAC 
ATTGATATTG AAGCTAGAAC AAGGGCCACC ACTTATTATC TAGCAGATCG TCGCTATGAC 
ATGCTGCCTT CCGTCCTCAG TGCAGATTTG TGTTCCCTTC TGGGAGGCGT TGATAGGTAT 
GCTGTAAGCA TCATGTGGGA ACTGGATAAA GCCTCTTATG AAATTAAGAA AGTGTGGTAT 
GGCAGAACCA TTATTCGATC AGCATACAAA CTGTTCTATG AAGCAGCCCA AGAACTACTG 
GATGGAAACT TAAGCGTTGT TGATGATATT CCAGAATTCA AAGACTTGGA TGAGAAGAGC 
AGACAAGCCA AGCTGGAGGA GTTGGTGTGG GCAATTGGAA AGCTGACCGA CATAGCTCGC 
CATGTCAGAG CTAAACGAGA CGGATGTGGT GCCCTGGAAC TGGAAGGGGT AGAGGTTTGC 
GTACAGCTAG ATGACAAAAA GAACATTCAC GACCTCATCC CCAAGCAGCC CCTGGAAGTC 
CACGAGACAG TGGCTGAATG CATGATCCTG GCCAACCACT GGGTCGCCAA AAAGATCTGG 
GAGAGCTTCC CTCATCAGGC CTTGCTGCGC CAGCACCCTC CTCCACACCA GGAGTTCTTT 
TCAGAACTCC GGGAATGTGC TAAAGCCAAA GGCTTCTTCA TAGATACACG GTCCAATAAA 
ACACTGGCTG ATTCTCTGGA TAATGCGAAC GACCCCCACG ATCCCATTGT GAACAGGCTA 
CTGCGCTCCA TGGCCACGCA GGCCATGTCG AATGCTCTGT ACTTCTCCAC CGGATCCTGT 
GCGGAGGAGG AGTTCCATCA TTACGGTCTT GCATTAGATA AATATACCCA CTTTACTTCT 
CCAATAAGAA GATATTCAGA TATTGTAGTA CACCGCTTGT TAATGGCAGC CATTTCAAAA 
GATAAGAAAA TGGAAATTAA GGGAAATCTG TTCAGCAACA AAGATCTTGA GGAATTATGC 
AGACATATCA ACAACAGAAA CCAAGCAGCA CAGCATTCTC AGAAGCAGTC TACTGAGCTC 
TTCCAGTGCA TGTACTTCAA AGACAAAGAC CCTGCCACCG AGGAGCGTTG CATATCTGAC 
GGAGTTATTT ATTCAATTAG AACAAATGGT GTGCTTCTAT TTATACCAAG GTTTGGGATT 
AAAGGTGCTG CTTATCTAAA AAATAAAGAT GGTTTAGTCA TCTCATGTGG CCCAGATAGC 
TGTTCTGAAT GGAAACCAGG ATCCCTTCAA CGATTTCAAA ACAAAATTAC CTCTACTACA 
ACAGATGGGG AATCTGTTAC GTTCCATTTG TTTGACCATG TAACCGTAAG AATATCCATA 
CAGGCCTCAC GTTGCCATTC TGATACAATC AGACTTGAAA TAATTAGTAA CAAACCATAC 
AAGATACCAA ATACAGAACT TATTCATCAG AGTTCCCCCT TGCTGAAGAG TGAGTTAGTG 
AAAGAAGTAA CTAAATCTGT GGAAGAAGCT CAGCTTGCCC AAGAAGTCAA AGTAAACATC 
ATTCAGGAGG AATATCAAGA ATATCGCCAA ACAAAGGGAA GGAGCCTATA CACACTTCTA 
GAGGAGATAC GGGACCTAGC TCTCCTGGAT GTTTCAAACA ATTATGGAAT ATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001310873.1
CDS	268..3381
Translation	MGRSRAGSPRELQASCCRCEADIACFAATDGKLLSSDVTHYVIPDWKVVQDYLEILEFPELKGIIFMQTACQAVQHQRGRRQYNKLRNLLKDARHDCILFANEFQQCCYLPRERGESMEKWQTRSIYNAAVWYYHHCQDRMPIVMVTEDEEAIQQYGSETEGVFVITFKNYLDNFWPDLKAAHELCDSILQSRRERENESQESHGKEYPEHLPLEVLEAGIKSGRYIQGILNVNKHRAQIEAFVRLQGASSKDSDLVSDILIHGMKARNRSIHGDVVVVELLPKNEWKGRTVALCENDCDDKASGESPSEPMPTGRVVGILQKNWRDYVVTFPSKEEVQSQGKNAQKILVTPWDYRIPKIRISTQQAETLQDFRVVVRIDSWESTSVYPNGHFVRVLGRIGDLEGEIATILVENSISVIPFSEAQMCEMPVNTPESPWKVSPEEEQKRKDLRKSHLVFSIDPKGCEDVDDTLSVRTLNNGNLELGVHIADVTHFVAPNSYIDIEARTRATTYYLADRRYDMLPSVLSADLCSLLGGVDRYAVSIMWELDKASYEIKKVWYGRTIIRSAYKLFYEAAQELLDGNLSVVDDIPEFKDLDEKSRQAKLEELVWAIGKLTDIARHVRAKRDGCGALELEGVEVCVQLDDKKNIHDLIPKQPLEVHETVAECMILANHWVAKKIWESFPHQALLRQHPPPHQEFFSELRECAKAKGFFIDTRSNKTLADSLDNANDPHDPIVNRLLRSMATQAMSNALYFSTGSCAEEEFHHYGLALDKYTHFTSPIRRYSDIVVHRLLMAAISKDKKMEIKGNLFSNKDLEELCRHINNRNQAAQHSQKQSTELFQCMYFKDKDPATEERCISDGVIYSIRTNGVLLFIPRFGIKGAAYLKNKDGLVISCGPDSCSEWKPGSLQRFQNKITSTTTDGESVTFHLFDHVTVRISIQASRCHSDTIRLEIISNKPYKIPNTELIHQSSPLLKSELVKEVTKSVEEAQLAQEVKVNIIQEEYQEYRQTKGRSLYTLLEEIRDLALLDVSNNYGI

Target ORF information:

RefSeq Version	NM_001323944.1
Organism	Homo sapiens(human)
Definition	Homo sapiens DIS3 like exosome 3'-5' exoribonuclease (DIS3L), transcript variant 10, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001323944.1

ORF Insert Sequence:

ATGGGGAGGT CCCGAGCTGG GAGCCCCCGG GAGCTACAGG CCAGCTGCTG CCGCTGCGAA 
GCTGACATCG CCTGCTTTGC AGCCACAGAT GGGAAACTCT TGTCTAGTGA TGTGACTCAT 
TACGTGATCC CAGACTGGAA AGTTGTTCAA GATTATCTTG AGATCCTTGA GTTTCCTGAG 
TTGAAGGGAA TTATTTTCAT GCAGACAGCT TGTCAAGCTG TGCAGCATCA AAGAGGCAGG 
AGACAGTATA ACAAACTGCG AAACCTGCTG AAGGATGCGC GTCATGATTG CATTCTCTTT 
GCTAATGAAT TCCAGCAATG CTGCTATCTG CCACGGGAAA GAGGAGAGTC CATGGAGAAG 
TGGCAGACCA GGAGCATATA CAACGCAGCT GTTTGGTACT ATCATCACTG CCAGGACAGG 
ATGCCAATTG TTATGGTGAC AGAAGATGAA GAGGCAATTC AGCAGTATGG AAGTGAAACA 
GAAGGAGTAT TCGTGATTAC TTTCAAGAAT TACCTGGACA ATTTCTGGCC TGATTTAAAA 
GCTGCCCACG AGCTTTGTGA TTCTATCCTT CAGTCTCGAC GGGAGAGAGA GAATGAGAGT 
CAGGAGAGCC ATGGGAAGGA GTACCCAGAA CATCTTCCCC TGGAAGTGTT AGAAGCTGGG 
ATTAAATCTG GACGCTATAT CCAGGGAATT CTGAATGTCA ACAAACACAG AGCCCAAATA 
GAAGCTTTTG TTCGACTTCA AGGAGCCAGC AGTAAAGATT CAGATTTAGT CAGTGACATC 
CTAATCCACG GGATGAAGGC TCGAAACCGC TCAATTCATG GAGATGTGGT AGTTGTGGAG 
CTGCTTCCTA AAAATGAATG GAAAGGAAGA ACCGTAGCCC TGTGTGAGAA TGACTGTGAC 
GACAAGGCTT CGGGCGAGTC CCCAAGTGAG CCCATGCCTA CAGGTCGAGT GGTGGGCATA 
CTTCAGAAGA ACTGGCGGGA TTATGTGGTG ACATTTCCGT CCAAAGAAGA GGTCCAATCT 
CAGGGCAAAA ATGCTCAGAA AATCCTGGTT ACACCTTGGG ATTACAGAAT TCCCAAAATT 
CGAATTAGCA CTCAGCAAGC AGAAACCCTC CAGGACTTCA GGGTGGTCGT GCGCATCGAT 
TCCTGGGAGT CAACATCTGT GTATCCAAAT GGACATTTTG TGCGTGTTTT AGGAAGAATC 
GGAGATCTGG AAGGGGAAAT TGCAACCATC CTGGTGGAAA ACAGTATTTC AGTTATTCCT 
TTCTCAGAAG CTCAGATGTG TGAGATGCCA GTAAACACAC CAGAAAGTCC CTGGAAGGTG 
AGTCCTGAAG AGGAACAAAA ACGTAAAGAC TTGAGGAAAA GCCATCTCGT ATTCAGCATT 
GACCCCAAAG GTTGTGAAGA TGTGGATGAC ACACTCTCAG TCAGAACCTT AAATAATGGC 
AACCTGGAAC TTGGGGTCCA CATCGCAGAT GTAACACACT TTGTGGCACC AAATTCTTAC 
ATTGATATTG AAGCTAGAAC AAGGGCCACC ACTTATTATC TAGCAGATCG TCGCTATGAC 
ATGCTGCCTT CCGTCCTCAG TGCAGATTTG TGTTCCCTTC TGGGAGGCGT TGATAGGTAT 
GCTGTAAGCA TCATGTGGGA ACTGGATAAA GCCTCTTATG AAATTAAGAA AGTGTGGTAT 
GGCAGAACCA TTATTCGATC AGCATACAAA CTGTTCTATG AAGCAGCCCA AGAACTACTG 
GATGGAAACT TAAGCGTTGT TGATGATATT CCAGAATTCA AAGACTTGGA TGAGAAGAGC 
AGACAAGCCA AGCTGGAGGA GTTGGTGTGG GCAATTGGAA AGCTGACCGA CATAGCTCGC 
CATGTCAGAG CTAAACGAGA CGGATGTGGT GCCCTGGAAC TGGAAGGGGT AGAGGTTTGC 
GTACAGCTAG ATGACAAAAA GAACATTCAC GACCTCATCC CCAAGCAGCC CCTGGAAGTC 
CACGAGACAG TGGCTGAATG CATGATCCTG GCCAACCACT GGGTCGCCAA AAAGATCTGG 
GAGAGCTTCC CTCATCAGGC CTTGCTGCGC CAGCACCCTC CTCCACACCA GGAGTTCTTT 
TCAGAACTCC GGGAATGTGC TAAAGCCAAA GGCTTCTTCA TAGATACACG GTCCAATAAA 
ACACTGGCTG ATTCTCTGGA TAATGCGAAC GACCCCCACG ATCCCATTGT GAACAGGCTA 
CTGCGCTCCA TGGCCACGCA GGCCATGTCG AATGCTCTGT ACTTCTCCAC CGGATCCTGT 
GCGGAGGAGG AGTTCCATCA TTACGGTCTT GCATTAGATA AATATACCCA CTTTACTTCT 
CCAATAAGAA GATATTCAGA TATTGTAGTA CACCGCTTGT TAATGGCAGC CATTTCAAAA 
GATAAGAAAA TGGAAATTAA GGGAAATCTG TTCAGCAACA AAGATCTTGA GGAATTATGC 
AGACATATCA ACAACAGAAA CCAAGCAGCA CAGCATTCTC AGAAGCAGTC TACTGAGCTC 
TTCCAGTGCA TGTACTTCAA AGACAAAGAC CCTGCCACCG AGGAGCGTTG CATATCTGAC 
GGAGTTATTT ATTCAATTAG AACAAATGGT GTGCTTCTAT TTATACCAAG GTTTGGGATT 
AAAGGTGCTG CTTATCTAAA AAATAAAGAT GGTTTAGTCA TCTCATGTGG CCCAGATAGC 
TGTTCTGAAT GGAAACCAGG ATCCCTTCAA CGATTTCAAA ACAAAATTAC CTCTACTACA 
ACAGATGGGG AATCTGTTAC GTTCCATTTG TTTGACCATG TAACCGTAAG AATATCCATA 
CAGGCCTCAC GTTGCCATTC TGATACAATC AGACTTGAAA TAATTAGTAA CAAACCATAC 
AAGATACCAA ATACAGAACT TATTCATCAG AGTTCCCCCT TGCTGAAGAG TGAGTTAGTG 
AAAGAAGTAA CTAAATCTGT GGAAGAAGCT CAGCTTGCCC AAGAAGTCAA AGTAAACATC 
ATTCAGGAGG AATATCAAGA ATATCGCCAA ACAAAGGGAA GGAGCCTATA CACACTTCTA 
GAGGAGATAC GGGACCTAGC TCTCCTGGAT GTTTCAAACA ATTATGGAAT ATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

DIS3L ( NM_001323944.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_001310873.1 Homo sapiens DIS3 like exosome 3'-5' exoribonuclease (DIS3L), transcript variant 10, mRNA.

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CloneID	OHu48094
Clone ID Related Accession (Same CDS sequence)	NM_001323944.1 , NM_001323944.2
Accession Version	NM_001323944.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 3114bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-09-27
Organism	Homo sapiens(human)
Product	DIS3-like exonuclease 1 isoform 6
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AC055855.9. On May 31, 2019 this sequence version replaced NM_001323944.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. ##Evidence-Data-START## Transcript exon combination :: SRR1803611.182580.1, SRR1803614.223921.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END##

ATGGGGAGGT CCCGAGCTGG GAGCCCCCGG GAGCTACAGG CCAGCTGCTG CCGCTGCGAA 
GCTGACATCG CCTGCTTTGC AGCCACAGAT GGGAAACTCT TGTCTAGTGA TGTGACTCAT 
TACGTGATCC CAGACTGGAA AGTTGTTCAA GATTATCTTG AGATCCTTGA GTTTCCTGAG 
TTGAAGGGAA TTATTTTCAT GCAGACAGCT TGTCAAGCTG TGCAGCATCA AAGAGGCAGG 
AGACAGTATA ACAAACTGCG AAACCTGCTG AAGGATGCGC GTCATGATTG CATTCTCTTT 
GCTAATGAAT TCCAGCAATG CTGCTATCTG CCACGGGAAA GAGGAGAGTC CATGGAGAAG 
TGGCAGACCA GGAGCATATA CAACGCAGCT GTTTGGTACT ATCATCACTG CCAGGACAGG 
ATGCCAATTG TTATGGTGAC AGAAGATGAA GAGGCAATTC AGCAGTATGG AAGTGAAACA 
GAAGGAGTAT TCGTGATTAC TTTCAAGAAT TACCTGGACA ATTTCTGGCC TGATTTAAAA 
GCTGCCCACG AGCTTTGTGA TTCTATCCTT CAGTCTCGAC GGGAGAGAGA GAATGAGAGT 
CAGGAGAGCC ATGGGAAGGA GTACCCAGAA CATCTTCCCC TGGAAGTGTT AGAAGCTGGG 
ATTAAATCTG GACGCTATAT CCAGGGAATT CTGAATGTCA ACAAACACAG AGCCCAAATA 
GAAGCTTTTG TTCGACTTCA AGGAGCCAGC AGTAAAGATT CAGATTTAGT CAGTGACATC 
CTAATCCACG GGATGAAGGC TCGAAACCGC TCAATTCATG GAGATGTGGT AGTTGTGGAG 
CTGCTTCCTA AAAATGAATG GAAAGGAAGA ACCGTAGCCC TGTGTGAGAA TGACTGTGAC 
GACAAGGCTT CGGGCGAGTC CCCAAGTGAG CCCATGCCTA CAGGTCGAGT GGTGGGCATA 
CTTCAGAAGA ACTGGCGGGA TTATGTGGTG ACATTTCCGT CCAAAGAAGA GGTCCAATCT 
CAGGGCAAAA ATGCTCAGAA AATCCTGGTT ACACCTTGGG ATTACAGAAT TCCCAAAATT 
CGAATTAGCA CTCAGCAAGC AGAAACCCTC CAGGACTTCA GGGTGGTCGT GCGCATCGAT 
TCCTGGGAGT CAACATCTGT GTATCCAAAT GGACATTTTG TGCGTGTTTT AGGAAGAATC 
GGAGATCTGG AAGGGGAAAT TGCAACCATC CTGGTGGAAA ACAGTATTTC AGTTATTCCT 
TTCTCAGAAG CTCAGATGTG TGAGATGCCA GTAAACACAC CAGAAAGTCC CTGGAAGGTG 
AGTCCTGAAG AGGAACAAAA ACGTAAAGAC TTGAGGAAAA GCCATCTCGT ATTCAGCATT 
GACCCCAAAG GTTGTGAAGA TGTGGATGAC ACACTCTCAG TCAGAACCTT AAATAATGGC 
AACCTGGAAC TTGGGGTCCA CATCGCAGAT GTAACACACT TTGTGGCACC AAATTCTTAC 
ATTGATATTG AAGCTAGAAC AAGGGCCACC ACTTATTATC TAGCAGATCG TCGCTATGAC 
ATGCTGCCTT CCGTCCTCAG TGCAGATTTG TGTTCCCTTC TGGGAGGCGT TGATAGGTAT 
GCTGTAAGCA TCATGTGGGA ACTGGATAAA GCCTCTTATG AAATTAAGAA AGTGTGGTAT 
GGCAGAACCA TTATTCGATC AGCATACAAA CTGTTCTATG AAGCAGCCCA AGAACTACTG 
GATGGAAACT TAAGCGTTGT TGATGATATT CCAGAATTCA AAGACTTGGA TGAGAAGAGC 
AGACAAGCCA AGCTGGAGGA GTTGGTGTGG GCAATTGGAA AGCTGACCGA CATAGCTCGC 
CATGTCAGAG CTAAACGAGA CGGATGTGGT GCCCTGGAAC TGGAAGGGGT AGAGGTTTGC 
GTACAGCTAG ATGACAAAAA GAACATTCAC GACCTCATCC CCAAGCAGCC CCTGGAAGTC 
CACGAGACAG TGGCTGAATG CATGATCCTG GCCAACCACT GGGTCGCCAA AAAGATCTGG 
GAGAGCTTCC CTCATCAGGC CTTGCTGCGC CAGCACCCTC CTCCACACCA GGAGTTCTTT 
TCAGAACTCC GGGAATGTGC TAAAGCCAAA GGCTTCTTCA TAGATACACG GTCCAATAAA 
ACACTGGCTG ATTCTCTGGA TAATGCGAAC GACCCCCACG ATCCCATTGT GAACAGGCTA 
CTGCGCTCCA TGGCCACGCA GGCCATGTCG AATGCTCTGT ACTTCTCCAC CGGATCCTGT 
GCGGAGGAGG AGTTCCATCA TTACGGTCTT GCATTAGATA AATATACCCA CTTTACTTCT 
CCAATAAGAA GATATTCAGA TATTGTAGTA CACCGCTTGT TAATGGCAGC CATTTCAAAA 
GATAAGAAAA TGGAAATTAA GGGAAATCTG TTCAGCAACA AAGATCTTGA GGAATTATGC 
AGACATATCA ACAACAGAAA CCAAGCAGCA CAGCATTCTC AGAAGCAGTC TACTGAGCTC 
TTCCAGTGCA TGTACTTCAA AGACAAAGAC CCTGCCACCG AGGAGCGTTG CATATCTGAC 
GGAGTTATTT ATTCAATTAG AACAAATGGT GTGCTTCTAT TTATACCAAG GTTTGGGATT 
AAAGGTGCTG CTTATCTAAA AAATAAAGAT GGTTTAGTCA TCTCATGTGG CCCAGATAGC 
TGTTCTGAAT GGAAACCAGG ATCCCTTCAA CGATTTCAAA ACAAAATTAC CTCTACTACA 
ACAGATGGGG AATCTGTTAC GTTCCATTTG TTTGACCATG TAACCGTAAG AATATCCATA 
CAGGCCTCAC GTTGCCATTC TGATACAATC AGACTTGAAA TAATTAGTAA CAAACCATAC 
AAGATACCAA ATACAGAACT TATTCATCAG AGTTCCCCCT TGCTGAAGAG TGAGTTAGTG 
AAAGAAGTAA CTAAATCTGT GGAAGAAGCT CAGCTTGCCC AAGAAGTCAA AGTAAACATC 
ATTCAGGAGG AATATCAAGA ATATCGCCAA ACAAAGGGAA GGAGCCTATA CACACTTCTA 
GAGGAGATAC GGGACCTAGC TCTCCTGGAT GTTTCAAACA ATTATGGAAT ATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001310873.1
CDS	273..3386
Translation	MGRSRAGSPRELQASCCRCEADIACFAATDGKLLSSDVTHYVIPDWKVVQDYLEILEFPELKGIIFMQTACQAVQHQRGRRQYNKLRNLLKDARHDCILFANEFQQCCYLPRERGESMEKWQTRSIYNAAVWYYHHCQDRMPIVMVTEDEEAIQQYGSETEGVFVITFKNYLDNFWPDLKAAHELCDSILQSRRERENESQESHGKEYPEHLPLEVLEAGIKSGRYIQGILNVNKHRAQIEAFVRLQGASSKDSDLVSDILIHGMKARNRSIHGDVVVVELLPKNEWKGRTVALCENDCDDKASGESPSEPMPTGRVVGILQKNWRDYVVTFPSKEEVQSQGKNAQKILVTPWDYRIPKIRISTQQAETLQDFRVVVRIDSWESTSVYPNGHFVRVLGRIGDLEGEIATILVENSISVIPFSEAQMCEMPVNTPESPWKVSPEEEQKRKDLRKSHLVFSIDPKGCEDVDDTLSVRTLNNGNLELGVHIADVTHFVAPNSYIDIEARTRATTYYLADRRYDMLPSVLSADLCSLLGGVDRYAVSIMWELDKASYEIKKVWYGRTIIRSAYKLFYEAAQELLDGNLSVVDDIPEFKDLDEKSRQAKLEELVWAIGKLTDIARHVRAKRDGCGALELEGVEVCVQLDDKKNIHDLIPKQPLEVHETVAECMILANHWVAKKIWESFPHQALLRQHPPPHQEFFSELRECAKAKGFFIDTRSNKTLADSLDNANDPHDPIVNRLLRSMATQAMSNALYFSTGSCAEEEFHHYGLALDKYTHFTSPIRRYSDIVVHRLLMAAISKDKKMEIKGNLFSNKDLEELCRHINNRNQAAQHSQKQSTELFQCMYFKDKDPATEERCISDGVIYSIRTNGVLLFIPRFGIKGAAYLKNKDGLVISCGPDSCSEWKPGSLQRFQNKITSTTTDGESVTFHLFDHVTVRISIQASRCHSDTIRLEIISNKPYKIPNTELIHQSSPLLKSELVKEVTKSVEEAQLAQEVKVNIIQEEYQEYRQTKGRSLYTLLEEIRDLALLDVSNNYGI

Target ORF information:

RefSeq Version	NM_001323944.2
Organism	Homo sapiens(human)
Definition	Homo sapiens DIS3 like exosome 3'-5' exoribonuclease (DIS3L), transcript variant 10, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001323944.2

ORF Insert Sequence:

ATGGGGAGGT CCCGAGCTGG GAGCCCCCGG GAGCTACAGG CCAGCTGCTG CCGCTGCGAA 
GCTGACATCG CCTGCTTTGC AGCCACAGAT GGGAAACTCT TGTCTAGTGA TGTGACTCAT 
TACGTGATCC CAGACTGGAA AGTTGTTCAA GATTATCTTG AGATCCTTGA GTTTCCTGAG 
TTGAAGGGAA TTATTTTCAT GCAGACAGCT TGTCAAGCTG TGCAGCATCA AAGAGGCAGG 
AGACAGTATA ACAAACTGCG AAACCTGCTG AAGGATGCGC GTCATGATTG CATTCTCTTT 
GCTAATGAAT TCCAGCAATG CTGCTATCTG CCACGGGAAA GAGGAGAGTC CATGGAGAAG 
TGGCAGACCA GGAGCATATA CAACGCAGCT GTTTGGTACT ATCATCACTG CCAGGACAGG 
ATGCCAATTG TTATGGTGAC AGAAGATGAA GAGGCAATTC AGCAGTATGG AAGTGAAACA 
GAAGGAGTAT TCGTGATTAC TTTCAAGAAT TACCTGGACA ATTTCTGGCC TGATTTAAAA 
GCTGCCCACG AGCTTTGTGA TTCTATCCTT CAGTCTCGAC GGGAGAGAGA GAATGAGAGT 
CAGGAGAGCC ATGGGAAGGA GTACCCAGAA CATCTTCCCC TGGAAGTGTT AGAAGCTGGG 
ATTAAATCTG GACGCTATAT CCAGGGAATT CTGAATGTCA ACAAACACAG AGCCCAAATA 
GAAGCTTTTG TTCGACTTCA AGGAGCCAGC AGTAAAGATT CAGATTTAGT CAGTGACATC 
CTAATCCACG GGATGAAGGC TCGAAACCGC TCAATTCATG GAGATGTGGT AGTTGTGGAG 
CTGCTTCCTA AAAATGAATG GAAAGGAAGA ACCGTAGCCC TGTGTGAGAA TGACTGTGAC 
GACAAGGCTT CGGGCGAGTC CCCAAGTGAG CCCATGCCTA CAGGTCGAGT GGTGGGCATA 
CTTCAGAAGA ACTGGCGGGA TTATGTGGTG ACATTTCCGT CCAAAGAAGA GGTCCAATCT 
CAGGGCAAAA ATGCTCAGAA AATCCTGGTT ACACCTTGGG ATTACAGAAT TCCCAAAATT 
CGAATTAGCA CTCAGCAAGC AGAAACCCTC CAGGACTTCA GGGTGGTCGT GCGCATCGAT 
TCCTGGGAGT CAACATCTGT GTATCCAAAT GGACATTTTG TGCGTGTTTT AGGAAGAATC 
GGAGATCTGG AAGGGGAAAT TGCAACCATC CTGGTGGAAA ACAGTATTTC AGTTATTCCT 
TTCTCAGAAG CTCAGATGTG TGAGATGCCA GTAAACACAC CAGAAAGTCC CTGGAAGGTG 
AGTCCTGAAG AGGAACAAAA ACGTAAAGAC TTGAGGAAAA GCCATCTCGT ATTCAGCATT 
GACCCCAAAG GTTGTGAAGA TGTGGATGAC ACACTCTCAG TCAGAACCTT AAATAATGGC 
AACCTGGAAC TTGGGGTCCA CATCGCAGAT GTAACACACT TTGTGGCACC AAATTCTTAC 
ATTGATATTG AAGCTAGAAC AAGGGCCACC ACTTATTATC TAGCAGATCG TCGCTATGAC 
ATGCTGCCTT CCGTCCTCAG TGCAGATTTG TGTTCCCTTC TGGGAGGCGT TGATAGGTAT 
GCTGTAAGCA TCATGTGGGA ACTGGATAAA GCCTCTTATG AAATTAAGAA AGTGTGGTAT 
GGCAGAACCA TTATTCGATC AGCATACAAA CTGTTCTATG AAGCAGCCCA AGAACTACTG 
GATGGAAACT TAAGCGTTGT TGATGATATT CCAGAATTCA AAGACTTGGA TGAGAAGAGC 
AGACAAGCCA AGCTGGAGGA GTTGGTGTGG GCAATTGGAA AGCTGACCGA CATAGCTCGC 
CATGTCAGAG CTAAACGAGA CGGATGTGGT GCCCTGGAAC TGGAAGGGGT AGAGGTTTGC 
GTACAGCTAG ATGACAAAAA GAACATTCAC GACCTCATCC CCAAGCAGCC CCTGGAAGTC 
CACGAGACAG TGGCTGAATG CATGATCCTG GCCAACCACT GGGTCGCCAA AAAGATCTGG 
GAGAGCTTCC CTCATCAGGC CTTGCTGCGC CAGCACCCTC CTCCACACCA GGAGTTCTTT 
TCAGAACTCC GGGAATGTGC TAAAGCCAAA GGCTTCTTCA TAGATACACG GTCCAATAAA 
ACACTGGCTG ATTCTCTGGA TAATGCGAAC GACCCCCACG ATCCCATTGT GAACAGGCTA 
CTGCGCTCCA TGGCCACGCA GGCCATGTCG AATGCTCTGT ACTTCTCCAC CGGATCCTGT 
GCGGAGGAGG AGTTCCATCA TTACGGTCTT GCATTAGATA AATATACCCA CTTTACTTCT 
CCAATAAGAA GATATTCAGA TATTGTAGTA CACCGCTTGT TAATGGCAGC CATTTCAAAA 
GATAAGAAAA TGGAAATTAA GGGAAATCTG TTCAGCAACA AAGATCTTGA GGAATTATGC 
AGACATATCA ACAACAGAAA CCAAGCAGCA CAGCATTCTC AGAAGCAGTC TACTGAGCTC 
TTCCAGTGCA TGTACTTCAA AGACAAAGAC CCTGCCACCG AGGAGCGTTG CATATCTGAC 
GGAGTTATTT ATTCAATTAG AACAAATGGT GTGCTTCTAT TTATACCAAG GTTTGGGATT 
AAAGGTGCTG CTTATCTAAA AAATAAAGAT GGTTTAGTCA TCTCATGTGG CCCAGATAGC 
TGTTCTGAAT GGAAACCAGG ATCCCTTCAA CGATTTCAAA ACAAAATTAC CTCTACTACA 
ACAGATGGGG AATCTGTTAC GTTCCATTTG TTTGACCATG TAACCGTAAG AATATCCATA 
CAGGCCTCAC GTTGCCATTC TGATACAATC AGACTTGAAA TAATTAGTAA CAAACCATAC 
AAGATACCAA ATACAGAACT TATTCATCAG AGTTCCCCCT TGCTGAAGAG TGAGTTAGTG 
AAAGAAGTAA CTAAATCTGT GGAAGAAGCT CAGCTTGCCC AAGAAGTCAA AGTAAACATC 
ATTCAGGAGG AATATCAAGA ATATCGCCAA ACAAAGGGAA GGAGCCTATA CACACTTCTA 
GAGGAGATAC GGGACCTAGC TCTCCTGGAT GTTTCAAACA ATTATGGAAT ATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Genome-based exome sequencing analysis identifies GYG1, DIS3L and DDRGK1 are associated with myocardial infarction in Koreans.
Journal of genetics96(6)1041-1046(2017 Dec)
Lee JY,Moon S,Kim YK,Lee SH,Lee BS,Park MY,Park JE,Jang Y,Han BG

Discovery of genetic biomarkers contributing to variation in drug response of cytidine analogues using human lymphoblastoid cell lines.
BMC genomics1593(2014 Feb)
Li L,Fridley BL,Kalari K,Niu N,Jenkins G,Batzler A,Abo RP,Schaid D,Wang L

Exonuclease hDIS3L2 specifies an exosome-independent 3'-5' degradation pathway of human cytoplasmic mRNA.
The EMBO journal32(13)1855-68(2013 Jul)
Lubas M,Damgaard CK,Tomecki R,Cysewski D,Jensen TH,Dziembowski A

The human core exosome interacts with differentially localized processive RNases: hDIS3 and hDIS3L.
The EMBO journal29(14)2342-57(2010 Jul)
Tomecki R,Kristiansen MS,Lykke-Andersen S,Chlebowski A,Larsen KM,Szczesny RJ,Drazkowska K,Pastula A,Andersen JS,Stepien PP,Dziembowski A,Jensen TH

Dis3-like 1: a novel exoribonuclease associated with the human exosome.
The EMBO journal29(14)2358-67(2010 Jul)
Staals RH,Bronkhorst AW,Schilders G,Slomovic S,Schuster G,Heck AJ,Raijmakers R,Pruijn GJ

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DIS3L cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

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