FBXO17 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	FBXO17
Entrez Gene ID	115290
Full Name	F-box protein 17
Synonyms	FBG4,FBX26,FBXO26,Fbx17
General protein information	Preferred Names F-box protein 17 Names F-box only protein 17 F-box only protein 26 F-box protein FBG4
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 19 Map Location: 19q13.2
Summary	This gene encodes a member of the F-box protein family which is characterized by the F-box motif. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class and it contains an F-box domain. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013].
Disorder MIM:	609094

mRNA and Protein(s)

mRNA	Protein	Name
NM_024907.7	NP_079183.4	F-box only protein 17 isoform 2
NM_024907.6	NP_079183.4	F-box only protein 17 isoform 2
NM_148169.2	NP_680474.1	F-box only protein 17 isoform 1

Pathways from BioSystems

Homologies

Rattus norvegicus (Norway rat)	Fbxo17	NP_001013082.2
Bos taurus (cattle)	FBXO17	NP_001096709.2
Pan troglodytes (chimpanzee)	FBXO27	XP_512645.3
Homo sapiens (human)	FBXO17	NP_680474.1
Canis lupus familiaris (dog)	FBXO17	XP_541630.4
Mus musculus (house mouse)	Fbxo17	NP_056611.2

Gene Ontology
Bibliography

Related articles in PubMed

Architecture of the human interactome defines protein communities and disease networks.
Huttlin EL, Bruckner RJ, Paulo JA, Cannon JR, Ting L, Baltier K, Colby G, Gebreab F, Gygi MP, Parzen H, Szpyt J, Tam S, Zarraga G, Pontano-Vaites L, Swarup S, White AE, Schweppe DK, Rad R, Erickson BK, Obar RA, Guruharsha KG, Li K, Artavanis-Tsakonas S, Gygi SP, Harper JW
Nature545(7655)505-509(2017 05)

SCF
Suber T, Wei J, Jacko AM, Nikolli I, Zhao Y, Zhao J, Mallampalli RK
The Journal of biological chemistry292(18)7452-7461(2017 05)

A Novel Function of F-Box Protein FBXO17 in Negative Regulation of Type I IFN Signaling by Recruiting PP2A for IFN Regulatory Factor 3 Deactivation.
Peng D, Wang Z, Huang A, Zhao Y, Qin FX
Journal of immunology (Baltimore, Md. : 1950)198(2)808-819(2017 Jan)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

identified FBXO17 as an F-box protein subunit that recognizes and mediates GSK3beta polyubiquitination.
Title: SCF

our studies identify a previously unreported role of FBXO17 in regulating IFN-I signaling
Title: A Novel Function of F-Box Protein FBXO17 in Negative Regulation of Type I IFN Signaling by Recruiting PP2A for IFN Regulatory Factor 3 Deactivation.

the apparent occurrence of an unusual TG 3' splice site in intron 3 is discussed
Title: Violating the splicing rules: TG dinucleotides function as alternative 3' splice sites in U2-dependent introns.

The following FBXO17 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the FBXO17 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu04278	NM_024907.7 Latest version!	Homo sapiens F-box protein 17 (FBXO17), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$139.30 $199.00
OHu06662	NM_148169.2 Latest version!	Homo sapiens F-box protein 17 (FBXO17), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$216.30 $309.00
View Old Accession Versions >>
OHu04278	NM_024907.6	Homo sapiens F-box protein 17 (FBXO17), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$139.30 $199.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

FBXO17 ( NM_024907.7 ) cDNA ORF clone, Homo sapiens(human) -> NP_079183.4 Homo sapiens F-box protein 17 (FBXO17), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu04278
Clone ID Related Accession (Same CDS sequence)	NM_024907.7 , NM_024907.6
Accession Version	NM_024907.7 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 837bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-10-09
Organism	Homo sapiens(human)
Product	F-box only protein 17 isoform 2
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from CF594009.1, AF386743.1, BM711851.1, CA429117.1 and AI050825.1. This sequence is a reference standard in the RefSeqGene project. On Nov 24, 2018 this sequence version replaced NM_024907.6. Transcript Variant: This variant (2) encodes the shorter isoform (2). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AF386743.1, SRR1660805.194695.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968189, SAMEA1968540 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000292852.9/ ENSP00000292852.3 RefSeq Select criteria :: based on conservation, expression ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGGGCGCCC GGCTATCGCG GCGACGGCTG CCGGCGGACC CATCCCTGGC CCTGGACGCG 
CTGCCCCCGG AGCTGCTGGT GCAGGTGCTG AGCCACGTGC CGCCACGCTC CTTGGTCACG 
CGATGCCGCC CAGTGTGCCG CGCCTGGCGC GACATAGTGG ACGGGCCCAC TGTGTGGCTG 
CTGCAGCTGG CCCGCGACCG CAGCGCCGAG GGCCGCGCAC TCTACGCAGT GGCTCAACGC 
TGCCTGCCCA GCAACGAAGA CAAGGAGGAG TTCCCGCTGT GCGCCCTGGC GCGCTACTGT 
CTGCGCGCGC CCTTCGGCCG CAATCTCATC TTCAACTCCT GCGGAGAGCA GGGCTTCAGA 
GGCTGGGAGG TGGAGCATGG CGGGAACGGC TGGGCCATAG AAAAGAACCT AACACCGGTG 
CCTGGGGCTC CTTCGCAGAC CTGCTTCGTG ACCTCTTTCG AATGGTGCTC CAAGAGGCAG 
CTTGTGGACC TGGTGATGGA AGGGGTGTGG CAGGAGCTGC TGGACAGCGC CCAGATTGAG 
ATCTGTGTGG CTGACTGGTG GGGCGCTCGA GAGAACTGCG GCTGCGTCTA CCAGCTCCGG 
GTCCGCCTTC TGGATGTGTA TGAAAAGGAA GTGGTCAAGT TCTCAGCCTC ACCTGACCCG 
GTCCTTCAGT GGACTGAGAG GGGCTGCCGA CAGGTCTCCC ACGTCTTCAC CAACTTTGGC 
AAGGGCATCC GCTACGTATC TTTTGAGCAG TACGGGAGAG ACGTGAGTTC CTGGGTGGGG 
CACTATGGCG CCCTTGTGAC CCACTCCAGT GTGAGGGTCA GGATCCGTCT GTCCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_079183.4
CDS	175..1011
Translation	MGARLSRRRLPADPSLALDALPPELLVQVLSHVPPRSLVTRCRPVCRAWRDIVDGPTVWLLQLARDRSAEGRALYAVAQRCLPSNEDKEEFPLCALARYCLRAPFGRNLIFNSCGEQGFRGWEVEHGGNGWAIEKNLTPVPGAPSQTCFVTSFEWCSKRQLVDLVMEGVWQELLDSAQIEICVADWWGARENCGCVYQLRVRLLDVYEKEVVKFSASPDPVLQWTERGCRQVSHVFTNFGKGIRYVSFEQYGRDVSSWVGHYGALVTHSSVRVRIRLS

Target ORF information:

RefSeq Version	NM_024907.7
Organism	Homo sapiens(human)
Definition	Homo sapiens F-box protein 17 (FBXO17), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_024907.7

ORF Insert Sequence:

ATGGGCGCCC GGCTATCGCG GCGACGGCTG CCGGCGGACC CATCCCTGGC CCTGGACGCG 
CTGCCCCCGG AGCTGCTGGT GCAGGTGCTG AGCCACGTGC CGCCACGCTC CTTGGTCACG 
CGATGCCGCC CAGTGTGCCG CGCCTGGCGC GACATAGTGG ACGGGCCCAC TGTGTGGCTG 
CTGCAGCTGG CCCGCGACCG CAGCGCCGAG GGCCGCGCAC TCTACGCAGT GGCTCAACGC 
TGCCTGCCCA GCAACGAAGA CAAGGAGGAG TTCCCGCTGT GCGCCCTGGC GCGCTACTGT 
CTGCGCGCGC CCTTCGGCCG CAATCTCATC TTCAACTCCT GCGGAGAGCA GGGCTTCAGA 
GGCTGGGAGG TGGAGCATGG CGGGAACGGC TGGGCCATAG AAAAGAACCT AACACCGGTG 
CCTGGGGCTC CTTCGCAGAC CTGCTTCGTG ACCTCTTTCG AATGGTGCTC CAAGAGGCAG 
CTTGTGGACC TGGTGATGGA AGGGGTGTGG CAGGAGCTGC TGGACAGCGC CCAGATTGAG 
ATCTGTGTGG CTGACTGGTG GGGCGCTCGA GAGAACTGCG GCTGCGTCTA CCAGCTCCGG 
GTCCGCCTTC TGGATGTGTA TGAAAAGGAA GTGGTCAAGT TCTCAGCCTC ACCTGACCCG 
GTCCTTCAGT GGACTGAGAG GGGCTGCCGA CAGGTCTCCC ACGTCTTCAC CAACTTTGGC 
AAGGGCATCC GCTACGTATC TTTTGAGCAG TACGGGAGAG ACGTGAGTTC CTGGGTGGGG 
CACTATGGCG CCCTTGTGAC CCACTCCAGT GTGAGGGTCA GGATCCGTCT GTCCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

FBXO17 ( NM_024907.6 ) cDNA ORF clone, Homo sapiens(human) -> NP_079183.4 Homo sapiens F-box protein 17 (FBXO17), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu04278
Clone ID Related Accession (Same CDS sequence)	NM_024907.7 , NM_024907.6
Accession Version	NM_024907.6	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 837bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-10-02
Organism	Homo sapiens(human)
Product	F-box only protein 17 isoform 2
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from CF594009.1, AF386743.1, BM711851.1, CA429117.1 and AI050825.1. This sequence is a reference standard in the RefSeqGene project. On Jul 31, 2013 this sequence version replaced NM_024907.5. Transcript Variant: This variant (2) encodes the shorter isoform (2). ##Evidence-Data-START## Transcript exon combination :: AF386743.1, SRR1660805.194695.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968189, SAMEA1968540 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGGCGCCC GGCTATCGCG GCGACGGCTG CCGGCGGACC CATCCCTGGC CCTGGACGCG 
CTGCCCCCGG AGCTGCTGGT GCAGGTGCTG AGCCACGTGC CGCCACGCTC CTTGGTCACG 
CGATGCCGCC CAGTGTGCCG CGCCTGGCGC GACATAGTGG ACGGGCCCAC TGTGTGGCTG 
CTGCAGCTGG CCCGCGACCG CAGCGCCGAG GGCCGCGCAC TCTACGCAGT GGCTCAACGC 
TGCCTGCCCA GCAACGAAGA CAAGGAGGAG TTCCCGCTGT GCGCCCTGGC GCGCTACTGT 
CTGCGCGCGC CCTTCGGCCG CAATCTCATC TTCAACTCCT GCGGAGAGCA GGGCTTCAGA 
GGCTGGGAGG TGGAGCATGG CGGGAACGGC TGGGCCATAG AAAAGAACCT AACACCGGTG 
CCTGGGGCTC CTTCGCAGAC CTGCTTCGTG ACCTCTTTCG AATGGTGCTC CAAGAGGCAG 
CTTGTGGACC TGGTGATGGA AGGGGTGTGG CAGGAGCTGC TGGACAGCGC CCAGATTGAG 
ATCTGTGTGG CTGACTGGTG GGGCGCTCGA GAGAACTGCG GCTGCGTCTA CCAGCTCCGG 
GTCCGCCTTC TGGATGTGTA TGAAAAGGAA GTGGTCAAGT TCTCAGCCTC ACCTGACCCG 
GTCCTTCAGT GGACTGAGAG GGGCTGCCGA CAGGTCTCCC ACGTCTTCAC CAACTTTGGC 
AAGGGCATCC GCTACGTATC TTTTGAGCAG TACGGGAGAG ACGTGAGTTC CTGGGTGGGG 
CACTATGGCG CCCTTGTGAC CCACTCCAGT GTGAGGGTCA GGATCCGTCT GTCCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_079183.4
CDS	246..1082
Translation	MGARLSRRRLPADPSLALDALPPELLVQVLSHVPPRSLVTRCRPVCRAWRDIVDGPTVWLLQLARDRSAEGRALYAVAQRCLPSNEDKEEFPLCALARYCLRAPFGRNLIFNSCGEQGFRGWEVEHGGNGWAIEKNLTPVPGAPSQTCFVTSFEWCSKRQLVDLVMEGVWQELLDSAQIEICVADWWGARENCGCVYQLRVRLLDVYEKEVVKFSASPDPVLQWTERGCRQVSHVFTNFGKGIRYVSFEQYGRDVSSWVGHYGALVTHSSVRVRIRLS

Target ORF information:

RefSeq Version	NM_024907.6
Organism	Homo sapiens(human)
Definition	Homo sapiens F-box protein 17 (FBXO17), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_024907.6

ORF Insert Sequence:

ATGGGCGCCC GGCTATCGCG GCGACGGCTG CCGGCGGACC CATCCCTGGC CCTGGACGCG 
CTGCCCCCGG AGCTGCTGGT GCAGGTGCTG AGCCACGTGC CGCCACGCTC CTTGGTCACG 
CGATGCCGCC CAGTGTGCCG CGCCTGGCGC GACATAGTGG ACGGGCCCAC TGTGTGGCTG 
CTGCAGCTGG CCCGCGACCG CAGCGCCGAG GGCCGCGCAC TCTACGCAGT GGCTCAACGC 
TGCCTGCCCA GCAACGAAGA CAAGGAGGAG TTCCCGCTGT GCGCCCTGGC GCGCTACTGT 
CTGCGCGCGC CCTTCGGCCG CAATCTCATC TTCAACTCCT GCGGAGAGCA GGGCTTCAGA 
GGCTGGGAGG TGGAGCATGG CGGGAACGGC TGGGCCATAG AAAAGAACCT AACACCGGTG 
CCTGGGGCTC CTTCGCAGAC CTGCTTCGTG ACCTCTTTCG AATGGTGCTC CAAGAGGCAG 
CTTGTGGACC TGGTGATGGA AGGGGTGTGG CAGGAGCTGC TGGACAGCGC CCAGATTGAG 
ATCTGTGTGG CTGACTGGTG GGGCGCTCGA GAGAACTGCG GCTGCGTCTA CCAGCTCCGG 
GTCCGCCTTC TGGATGTGTA TGAAAAGGAA GTGGTCAAGT TCTCAGCCTC ACCTGACCCG 
GTCCTTCAGT GGACTGAGAG GGGCTGCCGA CAGGTCTCCC ACGTCTTCAC CAACTTTGGC 
AAGGGCATCC GCTACGTATC TTTTGAGCAG TACGGGAGAG ACGTGAGTTC CTGGGTGGGG 
CACTATGGCG CCCTTGTGAC CCACTCCAGT GTGAGGGTCA GGATCCGTCT GTCCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

FBXO17 ( NM_148169.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_680474.1 Homo sapiens F-box protein 17 (FBXO17), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu06662
Clone ID Related Accession (Same CDS sequence)	NM_148169.2
Accession Version	NM_148169.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 864bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-10-09
Organism	Homo sapiens(human)
Product	F-box only protein 17 isoform 1
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AK057934.1, AF386743.1, BM711851.1, CA429117.1 and AI050825.1. On Jul 31, 2013 this sequence version replaced NM_148169.1. Transcript Variant: This variant (1) contains an alternate 5' terminal exon and initiates translation at an alternate start codon, compared to variant 2. It encodes isoform 1, which has a longer N-terminus, compared to isoform 2. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK057934.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2145774, SAMEA2159080 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGAAGCAAG GACTCTGGCT ACTGGAGATG GGCGCCCGGC TATCGCGGCG ACGGCTGCCG 
GCGGACCCAT CCCTGGCCCT GGACGCGCTG CCCCCGGAGC TGCTGGTGCA GGTGCTGAGC 
CACGTGCCGC CACGCTCCTT GGTCACGCGA TGCCGCCCAG TGTGCCGCGC CTGGCGCGAC 
ATAGTGGACG GGCCCACTGT GTGGCTGCTG CAGCTGGCCC GCGACCGCAG CGCCGAGGGC 
CGCGCACTCT ACGCAGTGGC TCAACGCTGC CTGCCCAGCA ACGAAGACAA GGAGGAGTTC 
CCGCTGTGCG CCCTGGCGCG CTACTGTCTG CGCGCGCCCT TCGGCCGCAA TCTCATCTTC 
AACTCCTGCG GAGAGCAGGG CTTCAGAGGC TGGGAGGTGG AGCATGGCGG GAACGGCTGG 
GCCATAGAAA AGAACCTAAC ACCGGTGCCT GGGGCTCCTT CGCAGACCTG CTTCGTGACC 
TCTTTCGAAT GGTGCTCCAA GAGGCAGCTT GTGGACCTGG TGATGGAAGG GGTGTGGCAG 
GAGCTGCTGG ACAGCGCCCA GATTGAGATC TGTGTGGCTG ACTGGTGGGG CGCTCGAGAG 
AACTGCGGCT GCGTCTACCA GCTCCGGGTC CGCCTTCTGG ATGTGTATGA AAAGGAAGTG 
GTCAAGTTCT CAGCCTCACC TGACCCGGTC CTTCAGTGGA CTGAGAGGGG CTGCCGACAG 
GTCTCCCACG TCTTCACCAA CTTTGGCAAG GGCATCCGCT ACGTATCTTT TGAGCAGTAC 
GGGAGAGACG TGAGTTCCTG GGTGGGGCAC TATGGCGCCC TTGTGACCCA CTCCAGTGTG 
AGGGTCAGGA TCCGTCTGTC CTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_680474.1
CDS	106..969
Translation	MKQGLWLLEMGARLSRRRLPADPSLALDALPPELLVQVLSHVPPRSLVTRCRPVCRAWRDIVDGPTVWLLQLARDRSAEGRALYAVAQRCLPSNEDKEEFPLCALARYCLRAPFGRNLIFNSCGEQGFRGWEVEHGGNGWAIEKNLTPVPGAPSQTCFVTSFEWCSKRQLVDLVMEGVWQELLDSAQIEICVADWWGARENCGCVYQLRVRLLDVYEKEVVKFSASPDPVLQWTERGCRQVSHVFTNFGKGIRYVSFEQYGRDVSSWVGHYGALVTHSSVRVRIRLS

Target ORF information:

RefSeq Version	NM_148169.2
Organism	Homo sapiens(human)
Definition	Homo sapiens F-box protein 17 (FBXO17), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_148169.2

ORF Insert Sequence:

ATGAAGCAAG GACTCTGGCT ACTGGAGATG GGCGCCCGGC TATCGCGGCG ACGGCTGCCG 
GCGGACCCAT CCCTGGCCCT GGACGCGCTG CCCCCGGAGC TGCTGGTGCA GGTGCTGAGC 
CACGTGCCGC CACGCTCCTT GGTCACGCGA TGCCGCCCAG TGTGCCGCGC CTGGCGCGAC 
ATAGTGGACG GGCCCACTGT GTGGCTGCTG CAGCTGGCCC GCGACCGCAG CGCCGAGGGC 
CGCGCACTCT ACGCAGTGGC TCAACGCTGC CTGCCCAGCA ACGAAGACAA GGAGGAGTTC 
CCGCTGTGCG CCCTGGCGCG CTACTGTCTG CGCGCGCCCT TCGGCCGCAA TCTCATCTTC 
AACTCCTGCG GAGAGCAGGG CTTCAGAGGC TGGGAGGTGG AGCATGGCGG GAACGGCTGG 
GCCATAGAAA AGAACCTAAC ACCGGTGCCT GGGGCTCCTT CGCAGACCTG CTTCGTGACC 
TCTTTCGAAT GGTGCTCCAA GAGGCAGCTT GTGGACCTGG TGATGGAAGG GGTGTGGCAG 
GAGCTGCTGG ACAGCGCCCA GATTGAGATC TGTGTGGCTG ACTGGTGGGG CGCTCGAGAG 
AACTGCGGCT GCGTCTACCA GCTCCGGGTC CGCCTTCTGG ATGTGTATGA AAAGGAAGTG 
GTCAAGTTCT CAGCCTCACC TGACCCGGTC CTTCAGTGGA CTGAGAGGGG CTGCCGACAG 
GTCTCCCACG TCTTCACCAA CTTTGGCAAG GGCATCCGCT ACGTATCTTT TGAGCAGTAC 
GGGAGAGACG TGAGTTCCTG GGTGGGGCAC TATGGCGCCC TTGTGACCCA CTCCAGTGTG 
AGGGTCAGGA TCCGTCTGTC CTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Architecture of the human interactome defines protein communities and disease networks.
Nature545(7655)505-509(2017 05)
Huttlin EL,Bruckner RJ,Paulo JA,Cannon JR,Ting L,Baltier K,Colby G,Gebreab F,Gygi MP,Parzen H,Szpyt J,Tam S,Zarraga G,Pontano-Vaites L,Swarup S,White AE,Schweppe DK,Rad R,Erickson BK,Obar RA,Guruharsha KG,Li K,Artavanis-Tsakonas S,Gygi SP,Harper JW

SCF
The Journal of biological chemistry292(18)7452-7461(2017 05)
Suber T,Wei J,Jacko AM,Nikolli I,Zhao Y,Zhao J,Mallampalli RK

A Novel Function of F-Box Protein FBXO17 in Negative Regulation of Type I IFN Signaling by Recruiting PP2A for IFN Regulatory Factor 3 Deactivation.
Journal of immunology (Baltimore, Md. : 1950)198(2)808-819(2017 Jan)
Peng D,Wang Z,Huang A,Zhao Y,Qin FX

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FBXO17 cDNA ORF clone, Homo sapiens(human)

Gene

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gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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