XKR4 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	XKR4
Entrez Gene ID	114786
Full Name	XK related 4
Synonyms	XRG4
General protein information	Preferred Names XK related 4 Names XK-related protein 4 X Kell blood group precursor-related family, member 4 X-linked Kx blood group related 4 XK, Kell blood group complex subunit-related family, member 4
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 8 Map Location: 8q12.1

mRNA and Protein(s)

mRNA	Protein	Name
NM_052898.1	NP_443130.1	XK-related protein 4
NM_052898.2	NP_443130.1	XK-related protein 4

Pathways from BioSystems

Homologies

Rattus norvegicus (Norway rat)	Xkr4	NP_001011971.1
Xenopus tropicalis (tropical clawed frog)	xkr4	NP_001027478.1
Mus musculus (house mouse)	Xkr4	NP_001011874.1
Gallus gallus (chicken)	LOC100858171	XP_004940021.1
Canis lupus familiaris (dog)	XKR4	XP_851429.2
Bos taurus (cattle)	XKR4	XP_002692696.1
Danio rerio (zebrafish)	zgc:123035	NP_001012258.1
Homo sapiens (human)	XKR4	NP_443130.1
Pan troglodytes (chimpanzee)	XKR4	NP_001028208.1

Gene Ontology
Bibliography

Related articles in PubMed

Genome-wide association study identifies a novel susceptibility gene for serum TSH levels in Chinese populations.
Zhan M, Chen G, Pan CM, Gu ZH, Zhao SX, Liu W, Wang HN, Ye XP, Xie HJ, Yu SS, Liang J, Gao GQ, Yuan GY, Zhang XM, Zuo CL, Su B, Huang W, Ning G, Chen SJ, Chen JL, Song HD,
Human molecular genetics23(20)5505-17(2014 Oct)

Genome-wide analysis of polymorphisms associated with cytokine responses in smallpox vaccine recipients.
Kennedy RB, Ovsyannikova IG, Pankratz VS, Haralambieva IH, Vierkant RA, Poland GA
Human genetics131(9)1403-21(2012 Sep)

Analysis of GWAS top hits in ADHD suggests association to two polymorphisms located in genes expressed in the cerebellum.
Lantieri F, Glessner JT, Hakonarson H, Elia J, Devoto M
American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics153B(6)1127-33(2010 Sep)

Association of the NPAS3 gene and five other loci with response to the antipsychotic iloperidone identified in a whole genome association study.
Lavedan C, Licamele L, Volpi S, Hamilton J, Heaton C, Mack K, Lannan R, Thompson A, Wolfgang CD, Polymeropoulos MH
Molecular psychiatry14(8)804-19(2009 Aug)

Applicability of a genetic signature for enhanced iloperidone efficacy in the treatment of schizophrenia.
Volpi S, Potkin SG, Malhotra AK, Licamele L, Lavedan C
The Journal of clinical psychiatry70(6)801-9(2009 Jun)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Findings suggest that the SNPs in XKR4 and near FOXE1 are involved in the regulation of TSH levels.
Title: Genome-wide association study identifies a novel susceptibility gene for serum TSH levels in Chinese populations.

Two SNPs located in genes coding for as yet uncharacterized proteins expressed in the cerebellum, XKR4 in 8q12.1, and FAM190A in 4q22.1 suggest association with association with attention deficit hyperactivity disorder. [XkR4]
Title: Analysis of GWAS top hits in ADHD suggests association to two polymorphisms located in genes expressed in the cerebellum.

Clinical trial of gene-disease association and gene-environment interaction. (HuGE Navigator)
Title: Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.

Genome-wide association study of gene-disease association. (HuGE Navigator)
Title: Association of the NPAS3 gene and five other loci with response to the antipsychotic iloperidone identified in a whole genome association study.

Clinical trial of gene-disease association, gene-gene interaction, gene-environment interaction, and pharmacogenomic / toxicogenomic. (HuGE Navigator)
Title: Applicability of a genetic signature for enhanced iloperidone efficacy in the treatment of schizophrenia.

The following XKR4 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the XKR4 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu29692	NM_052898.2 Latest version!	Homo sapiens XK related 4 (XKR4), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$384.30 $549.00
View Old Accession Versions >>
OHu29692	NM_052898.1	Homo sapiens XK related 4 (XKR4), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$384.30 $549.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

XKR4 ( NM_052898.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_443130.1 Homo sapiens XK related 4 (XKR4), mRNA.

Price & Availability↑

CloneID	OHu29692
Clone ID Related Accession (Same CDS sequence)	NM_052898.1 , NM_052898.2
Accession Version	NM_052898.1	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1953bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-02-16
Organism	Homo sapiens(human)
Product	XK-related protein 4
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AY534241.1. On Feb 14, 2005 this sequence version replaced XM_056298.6. ##Evidence-Data-START## Transcript exon combination :: AY534241.1, AB067476.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968540, SAMEA2142348 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGCCGCTA AATCAGACGG GAGGCTGAAA ATGAAGAAAA GCAGCGACGT GGCGTTCACC 
CCGCTGCAGA ACTCGGACCA CTCGGGCTCG GTGCAGGGAT TGGCTCCAGG CTTGCCGTCG 
GGGTCGGGAG CCGAGGACGA GGAGGCGGCC GGGGGCGGCT GCTGCCCGGA CGGCGGCGGC 
TGCTCGCGCT GCTGCTGCTG CTGCGCCGGG AGTGGCGGCT CCGCGGGCTC GGGCGGCTCC 
GGCGGCGTCG CCGGCCCGGG CGGCGGCGGG GCGGGCTCGG CTGCGCTGTG CCTGCGCCTG 
GGCAGGGAGC AGCGGCGCTA CTCACTGTGG GACTGCCTCT GGATCCTGGC CGCCGTGGCC 
GTGTACTTCG CGGACGTGGG CACAGACGTC TGGCTCGCCG TGGACTACTA CCTGCGCGGC 
CAGCGCTGGT GGTTCGGGCT CACGCTCTTC TTCGTGGTGC TCGGCTCTCT GTCGGTGCAA 
GTGTTCAGCT TCCGCTGGTT TGTGCACGAT TTCAGCACCG AGGACAGCGC CACGGCCGCT 
GCTGCCTCCA GCTGCCCGCA GCCTGGAGCC GATTGCAAGA CGGTGGTCGG CGGTGGGTCT 
GCAGCCGGGG AAGGCGAGGC TCGTCCTTCC ACGCCGCAAA GGCAAGCATC TAACGCCAGC 
AAGAGCAACA TCGCCGCGGC CAACAGCGGC AGCAACAGCA GCGGGGCTAC CCGGGCCAGT 
GGCAAGCACA GGTCTGCGTC CTGCTCCTTC TGCATCTGGC TCCTGCAGTC ACTCATCCAC 
ATCTTGCAGC TCGGGCAAAT CTGGAGATAT TTCCACACAA TATACTTAGG TATTCGAAGC 
CGACAGAGTG GGGAGAATGA CAGATGGAGG TTTTACTGGA AAATGGTATA TGAGTATGCG 
GATGTGAGTA TGCTGCATTT GCTAGCCACC TTTCTGGAAA GTGCTCCACA GCTGGTCCTG 
CAGCTCTGCA TTATCGTACA GACTCATAGC TTACAGGCCC TCCAAGGTTT CACAGCGGCA 
GCTTCCCTCG TGTCCCTGGC CTGGGCCTTG GCCTCCTACC AGAAGGCCCT CCGGGACTCT 
CGAGATGACA AGAAGCCCAT CAGCTACATG GCCGTCATCA TCCAGTTCTG CTGGCACTTC 
TTCACCATCG CCGCCAGGGT CATCACGTTT GCCCTCTTTG CCTCGGTTTT CCAGCTGTAC 
TTTGGGATCT TCATCGTCCT TCACTGGTGC ATCATGACCT TCTGGATCGT CCACTGTGAG 
ACAGAATTCT GTATCACCAA ATGGGAAGAG ATTGTGTTCG ACATGGTGGT GGGGATTATC 
TATATCTTCA GTTGGTTCAA TGTCAAGGAA GGCAGGACAC GCTGCAGGCT ATTCATTTAC 
TATTTTGTGA TCCTTTTGGA AAATACAGCC TTGAGTGCCC TCTGGTACCT CTACAAGGCT 
CCCCAGATTG CAGACGCATT TGCCATTCCA GCGCTGTGTG TGGTGTTCAG CAGCTTTTTA 
ACTGGCGTTG TTTTTATGCT GATGTATTAT GCCTTCTTTC ATCCCAATGG ACCCAGATTC 
GGGCAGTCAC CAAGTTGTGC TTGTGAGGAC CCAGCCGCTG CCTTCACTTT GCCCCCAGAC 
GTGGCCACAA GCACCCTACG GTCCATCTCC AACAACCGCA GTGTTGTCAG CGACCGCGAT 
CAGAAATTCG CAGAGCGGGA TGGGTGTGTA CCTGTCTTTC AAGTGAGGCC CACTGCCCCA 
TCCACCCCAT CATCTCGCCC ACCACGGATT GAAGAATCAG TCATTAAAAT TGACTTGTTC 
AGGAATAGGT ACCCAGCATG GGAGAGACAT GTTTTGGACC GAAGCCTCCG AAAGGCTATT 
TTAGCTTTTG AATGTTCCCC ATCTCCTCCA AGGCTGCAGT ACAAAGATGA TGCCCTTATT 
CAGGAGCGGT TGGAGTACGA AACCACTTTA TAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_443130.1
CDS	33..1985
Translation	MAAKSDGRLKMKKSSDVAFTPLQNSDHSGSVQGLAPGLPSGSGAEDEEAAGGGCCPDGGGCSRCCCCCAGSGGSAGSGGSGGVAGPGGGGAGSAALCLRLGREQRRYSLWDCLWILAAVAVYFADVGTDVWLAVDYYLRGQRWWFGLTLFFVVLGSLSVQVFSFRWFVHDFSTEDSATAAAASSCPQPGADCKTVVGGGSAAGEGEARPSTPQRQASNASKSNIAAANSGSNSSGATRASGKHRSASCSFCIWLLQSLIHILQLGQIWRYFHTIYLGIRSRQSGENDRWRFYWKMVYEYADVSMLHLLATFLESAPQLVLQLCIIVQTHSLQALQGFTAAASLVSLAWALASYQKALRDSRDDKKPISYMAVIIQFCWHFFTIAARVITFALFASVFQLYFGIFIVLHWCIMTFWIVHCETEFCITKWEEIVFDMVVGIIYIFSWFNVKEGRTRCRLFIYYFVILLENTALSALWYLYKAPQIADAFAIPALCVVFSSFLTGVVFMLMYYAFFHPNGPRFGQSPSCACEDPAAAFTLPPDVATSTLRSISNNRSVVSDRDQKFAERDGCVPVFQVRPTAPSTPSSRPPRIEESVIKIDLFRNRYPAWERHVLDRSLRKAILAFECSPSPPRLQYKDDALIQERLEYETTL

Target ORF information:

RefSeq Version	NM_052898.1
Organism	Homo sapiens(human)
Definition	Homo sapiens XK related 4 (XKR4), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_052898.1

ORF Insert Sequence:

ATGGCCGCTA AATCAGACGG GAGGCTGAAA ATGAAGAAAA GCAGCGACGT GGCGTTCACC 
CCGCTGCAGA ACTCGGACCA CTCGGGCTCG GTGCAGGGAT TGGCTCCAGG CTTGCCGTCG 
GGGTCGGGAG CCGAGGACGA GGAGGCGGCC GGGGGCGGCT GCTGCCCGGA CGGCGGCGGC 
TGCTCGCGCT GCTGCTGCTG CTGCGCCGGG AGTGGCGGCT CCGCGGGCTC GGGCGGCTCC 
GGCGGCGTCG CCGGCCCGGG CGGCGGCGGG GCGGGCTCGG CTGCGCTGTG CCTGCGCCTG 
GGCAGGGAGC AGCGGCGCTA CTCACTGTGG GACTGCCTCT GGATCCTGGC CGCCGTGGCC 
GTGTACTTCG CGGACGTGGG CACAGACGTC TGGCTCGCCG TGGACTACTA CCTGCGCGGC 
CAGCGCTGGT GGTTCGGGCT CACGCTCTTC TTCGTGGTGC TCGGCTCTCT GTCGGTGCAA 
GTGTTCAGCT TCCGCTGGTT TGTGCACGAT TTCAGCACCG AGGACAGCGC CACGGCCGCT 
GCTGCCTCCA GCTGCCCGCA GCCTGGAGCC GATTGCAAGA CGGTGGTCGG CGGTGGGTCT 
GCAGCCGGGG AAGGCGAGGC TCGTCCTTCC ACGCCGCAAA GGCAAGCATC TAACGCCAGC 
AAGAGCAACA TCGCCGCGGC CAACAGCGGC AGCAACAGCA GCGGGGCTAC CCGGGCCAGT 
GGCAAGCACA GGTCTGCGTC CTGCTCCTTC TGCATCTGGC TCCTGCAGTC ACTCATCCAC 
ATCTTGCAGC TCGGGCAAAT CTGGAGATAT TTCCACACAA TATACTTAGG TATTCGAAGC 
CGACAGAGTG GGGAGAATGA CAGATGGAGG TTTTACTGGA AAATGGTATA TGAGTATGCG 
GATGTGAGTA TGCTGCATTT GCTAGCCACC TTTCTGGAAA GTGCTCCACA GCTGGTCCTG 
CAGCTCTGCA TTATCGTACA GACTCATAGC TTACAGGCCC TCCAAGGTTT CACAGCGGCA 
GCTTCCCTCG TGTCCCTGGC CTGGGCCTTG GCCTCCTACC AGAAGGCCCT CCGGGACTCT 
CGAGATGACA AGAAGCCCAT CAGCTACATG GCCGTCATCA TCCAGTTCTG CTGGCACTTC 
TTCACCATCG CCGCCAGGGT CATCACGTTT GCCCTCTTTG CCTCGGTTTT CCAGCTGTAC 
TTTGGGATCT TCATCGTCCT TCACTGGTGC ATCATGACCT TCTGGATCGT CCACTGTGAG 
ACAGAATTCT GTATCACCAA ATGGGAAGAG ATTGTGTTCG ACATGGTGGT GGGGATTATC 
TATATCTTCA GTTGGTTCAA TGTCAAGGAA GGCAGGACAC GCTGCAGGCT ATTCATTTAC 
TATTTTGTGA TCCTTTTGGA AAATACAGCC TTGAGTGCCC TCTGGTACCT CTACAAGGCT 
CCCCAGATTG CAGACGCATT TGCCATTCCA GCGCTGTGTG TGGTGTTCAG CAGCTTTTTA 
ACTGGCGTTG TTTTTATGCT GATGTATTAT GCCTTCTTTC ATCCCAATGG ACCCAGATTC 
GGGCAGTCAC CAAGTTGTGC TTGTGAGGAC CCAGCCGCTG CCTTCACTTT GCCCCCAGAC 
GTGGCCACAA GCACCCTACG GTCCATCTCC AACAACCGCA GTGTTGTCAG CGACCGCGAT 
CAGAAATTCG CAGAGCGGGA TGGGTGTGTA CCTGTCTTTC AAGTGAGGCC CACTGCCCCA 
TCCACCCCAT CATCTCGCCC ACCACGGATT GAAGAATCAG TCATTAAAAT TGACTTGTTC 
AGGAATAGGT ACCCAGCATG GGAGAGACAT GTTTTGGACC GAAGCCTCCG AAAGGCTATT 
TTAGCTTTTG AATGTTCCCC ATCTCCTCCA AGGCTGCAGT ACAAAGATGA TGCCCTTATT 
CAGGAGCGGT TGGAGTACGA AACCACTTTA TAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

XKR4 ( NM_052898.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_443130.1 Homo sapiens XK related 4 (XKR4), mRNA.

Price & Availability↑

CloneID	OHu29692
Clone ID Related Accession (Same CDS sequence)	NM_052898.1 , NM_052898.2
Accession Version	NM_052898.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1953bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-10-25
Organism	Homo sapiens(human)
Product	XK-related protein 4
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC022679.9, AY534241.1 and AC090200.4. On May 17, 2019 this sequence version replaced NM_052898.1. ##Evidence-Data-START## Transcript exon combination :: AY534241.1, AB067476.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968540, SAMEA2142348 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000327381.7/ ENSP00000328326.5 RefSeq Select criteria :: based on single protein-coding transcript ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGGCCGCTA AATCAGACGG GAGGCTGAAA ATGAAGAAAA GCAGCGACGT GGCGTTCACC 
CCGCTGCAGA ACTCGGACCA CTCGGGCTCG GTGCAGGGAT TGGCTCCAGG CTTGCCGTCG 
GGGTCGGGAG CCGAGGACGA GGAGGCGGCC GGGGGCGGCT GCTGCCCGGA CGGCGGCGGC 
TGCTCGCGCT GCTGCTGCTG CTGCGCCGGG AGTGGCGGCT CCGCGGGCTC GGGCGGCTCC 
GGCGGCGTCG CCGGCCCGGG CGGCGGCGGG GCGGGCTCGG CTGCGCTGTG CCTGCGCCTG 
GGCAGGGAGC AGCGGCGCTA CTCACTGTGG GACTGCCTCT GGATCCTGGC CGCCGTGGCC 
GTGTACTTCG CGGACGTGGG CACAGACGTC TGGCTCGCCG TGGACTACTA CCTGCGCGGC 
CAGCGCTGGT GGTTCGGGCT CACGCTCTTC TTCGTGGTGC TCGGCTCTCT GTCGGTGCAA 
GTGTTCAGCT TCCGCTGGTT TGTGCACGAT TTCAGCACCG AGGACAGCGC CACGGCCGCT 
GCTGCCTCCA GCTGCCCGCA GCCTGGAGCC GATTGCAAGA CGGTGGTCGG CGGTGGGTCT 
GCAGCCGGGG AAGGCGAGGC TCGTCCTTCC ACGCCGCAAA GGCAAGCATC TAACGCCAGC 
AAGAGCAACA TCGCCGCGGC CAACAGCGGC AGCAACAGCA GCGGGGCTAC CCGGGCCAGT 
GGCAAGCACA GGTCTGCGTC CTGCTCCTTC TGCATCTGGC TCCTGCAGTC ACTCATCCAC 
ATCTTGCAGC TCGGGCAAAT CTGGAGATAT TTCCACACAA TATACTTAGG TATTCGAAGC 
CGACAGAGTG GGGAGAATGA CAGATGGAGG TTTTACTGGA AAATGGTATA TGAGTATGCG 
GATGTGAGTA TGCTGCATTT GCTAGCCACC TTTCTGGAAA GTGCTCCACA GCTGGTCCTG 
CAGCTCTGCA TTATCGTACA GACTCATAGC TTACAGGCCC TCCAAGGTTT CACAGCGGCA 
GCTTCCCTCG TGTCCCTGGC CTGGGCCTTG GCCTCCTACC AGAAGGCCCT CCGGGACTCT 
CGAGATGACA AGAAGCCCAT CAGCTACATG GCCGTCATCA TCCAGTTCTG CTGGCACTTC 
TTCACCATCG CCGCCAGGGT CATCACGTTT GCCCTCTTTG CCTCGGTTTT CCAGCTGTAC 
TTTGGGATCT TCATCGTCCT TCACTGGTGC ATCATGACCT TCTGGATCGT CCACTGTGAG 
ACAGAATTCT GTATCACCAA ATGGGAAGAG ATTGTGTTCG ACATGGTGGT GGGGATTATC 
TATATCTTCA GTTGGTTCAA TGTCAAGGAA GGCAGGACAC GCTGCAGGCT ATTCATTTAC 
TATTTTGTGA TCCTTTTGGA AAATACAGCC TTGAGTGCCC TCTGGTACCT CTACAAGGCT 
CCCCAGATTG CAGACGCATT TGCCATTCCA GCGCTGTGTG TGGTGTTCAG CAGCTTTTTA 
ACTGGCGTTG TTTTTATGCT GATGTATTAT GCCTTCTTTC ATCCCAATGG ACCCAGATTC 
GGGCAGTCAC CAAGTTGTGC TTGTGAGGAC CCAGCCGCTG CCTTCACTTT GCCCCCAGAC 
GTGGCCACAA GCACCCTACG GTCCATCTCC AACAACCGCA GTGTTGTCAG CGACCGCGAT 
CAGAAATTCG CAGAGCGGGA TGGGTGTGTA CCTGTCTTTC AAGTGAGGCC CACTGCCCCA 
TCCACCCCAT CATCTCGCCC ACCACGGATT GAAGAATCAG TCATTAAAAT TGACTTGTTC 
AGGAATAGGT ACCCAGCATG GGAGAGACAT GTTTTGGACC GAAGCCTCCG AAAGGCTATT 
TTAGCTTTTG AATGTTCCCC ATCTCCTCCA AGGCTGCAGT ACAAAGATGA TGCCCTTATT 
CAGGAGCGGT TGGAGTACGA AACCACTTTA TAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_443130.1
CDS	462..2414
Translation	MAAKSDGRLKMKKSSDVAFTPLQNSDHSGSVQGLAPGLPSGSGAEDEEAAGGGCCPDGGGCSRCCCCCAGSGGSAGSGGSGGVAGPGGGGAGSAALCLRLGREQRRYSLWDCLWILAAVAVYFADVGTDVWLAVDYYLRGQRWWFGLTLFFVVLGSLSVQVFSFRWFVHDFSTEDSATAAAASSCPQPGADCKTVVGGGSAAGEGEARPSTPQRQASNASKSNIAAANSGSNSSGATRASGKHRSASCSFCIWLLQSLIHILQLGQIWRYFHTIYLGIRSRQSGENDRWRFYWKMVYEYADVSMLHLLATFLESAPQLVLQLCIIVQTHSLQALQGFTAAASLVSLAWALASYQKALRDSRDDKKPISYMAVIIQFCWHFFTIAARVITFALFASVFQLYFGIFIVLHWCIMTFWIVHCETEFCITKWEEIVFDMVVGIIYIFSWFNVKEGRTRCRLFIYYFVILLENTALSALWYLYKAPQIADAFAIPALCVVFSSFLTGVVFMLMYYAFFHPNGPRFGQSPSCACEDPAAAFTLPPDVATSTLRSISNNRSVVSDRDQKFAERDGCVPVFQVRPTAPSTPSSRPPRIEESVIKIDLFRNRYPAWERHVLDRSLRKAILAFECSPSPPRLQYKDDALIQERLEYETTL

Target ORF information:

RefSeq Version	NM_052898.2
Organism	Homo sapiens(human)
Definition	Homo sapiens XK related 4 (XKR4), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_052898.2

ORF Insert Sequence:

ATGGCCGCTA AATCAGACGG GAGGCTGAAA ATGAAGAAAA GCAGCGACGT GGCGTTCACC 
CCGCTGCAGA ACTCGGACCA CTCGGGCTCG GTGCAGGGAT TGGCTCCAGG CTTGCCGTCG 
GGGTCGGGAG CCGAGGACGA GGAGGCGGCC GGGGGCGGCT GCTGCCCGGA CGGCGGCGGC 
TGCTCGCGCT GCTGCTGCTG CTGCGCCGGG AGTGGCGGCT CCGCGGGCTC GGGCGGCTCC 
GGCGGCGTCG CCGGCCCGGG CGGCGGCGGG GCGGGCTCGG CTGCGCTGTG CCTGCGCCTG 
GGCAGGGAGC AGCGGCGCTA CTCACTGTGG GACTGCCTCT GGATCCTGGC CGCCGTGGCC 
GTGTACTTCG CGGACGTGGG CACAGACGTC TGGCTCGCCG TGGACTACTA CCTGCGCGGC 
CAGCGCTGGT GGTTCGGGCT CACGCTCTTC TTCGTGGTGC TCGGCTCTCT GTCGGTGCAA 
GTGTTCAGCT TCCGCTGGTT TGTGCACGAT TTCAGCACCG AGGACAGCGC CACGGCCGCT 
GCTGCCTCCA GCTGCCCGCA GCCTGGAGCC GATTGCAAGA CGGTGGTCGG CGGTGGGTCT 
GCAGCCGGGG AAGGCGAGGC TCGTCCTTCC ACGCCGCAAA GGCAAGCATC TAACGCCAGC 
AAGAGCAACA TCGCCGCGGC CAACAGCGGC AGCAACAGCA GCGGGGCTAC CCGGGCCAGT 
GGCAAGCACA GGTCTGCGTC CTGCTCCTTC TGCATCTGGC TCCTGCAGTC ACTCATCCAC 
ATCTTGCAGC TCGGGCAAAT CTGGAGATAT TTCCACACAA TATACTTAGG TATTCGAAGC 
CGACAGAGTG GGGAGAATGA CAGATGGAGG TTTTACTGGA AAATGGTATA TGAGTATGCG 
GATGTGAGTA TGCTGCATTT GCTAGCCACC TTTCTGGAAA GTGCTCCACA GCTGGTCCTG 
CAGCTCTGCA TTATCGTACA GACTCATAGC TTACAGGCCC TCCAAGGTTT CACAGCGGCA 
GCTTCCCTCG TGTCCCTGGC CTGGGCCTTG GCCTCCTACC AGAAGGCCCT CCGGGACTCT 
CGAGATGACA AGAAGCCCAT CAGCTACATG GCCGTCATCA TCCAGTTCTG CTGGCACTTC 
TTCACCATCG CCGCCAGGGT CATCACGTTT GCCCTCTTTG CCTCGGTTTT CCAGCTGTAC 
TTTGGGATCT TCATCGTCCT TCACTGGTGC ATCATGACCT TCTGGATCGT CCACTGTGAG 
ACAGAATTCT GTATCACCAA ATGGGAAGAG ATTGTGTTCG ACATGGTGGT GGGGATTATC 
TATATCTTCA GTTGGTTCAA TGTCAAGGAA GGCAGGACAC GCTGCAGGCT ATTCATTTAC 
TATTTTGTGA TCCTTTTGGA AAATACAGCC TTGAGTGCCC TCTGGTACCT CTACAAGGCT 
CCCCAGATTG CAGACGCATT TGCCATTCCA GCGCTGTGTG TGGTGTTCAG CAGCTTTTTA 
ACTGGCGTTG TTTTTATGCT GATGTATTAT GCCTTCTTTC ATCCCAATGG ACCCAGATTC 
GGGCAGTCAC CAAGTTGTGC TTGTGAGGAC CCAGCCGCTG CCTTCACTTT GCCCCCAGAC 
GTGGCCACAA GCACCCTACG GTCCATCTCC AACAACCGCA GTGTTGTCAG CGACCGCGAT 
CAGAAATTCG CAGAGCGGGA TGGGTGTGTA CCTGTCTTTC AAGTGAGGCC CACTGCCCCA 
TCCACCCCAT CATCTCGCCC ACCACGGATT GAAGAATCAG TCATTAAAAT TGACTTGTTC 
AGGAATAGGT ACCCAGCATG GGAGAGACAT GTTTTGGACC GAAGCCTCCG AAAGGCTATT 
TTAGCTTTTG AATGTTCCCC ATCTCCTCCA AGGCTGCAGT ACAAAGATGA TGCCCTTATT 
CAGGAGCGGT TGGAGTACGA AACCACTTTA TAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Genome-wide association study identifies a novel susceptibility gene for serum TSH levels in Chinese populations.
Human molecular genetics23(20)5505-17(2014 Oct)
Zhan M,Chen G,Pan CM,Gu ZH,Zhao SX,Liu W,Wang HN,Ye XP,Xie HJ,Yu SS,Liang J,Gao GQ,Yuan GY,Zhang XM,Zuo CL,Su B,Huang W,Ning G,Chen SJ,Chen JL,Song HD,

Genome-wide analysis of polymorphisms associated with cytokine responses in smallpox vaccine recipients.
Human genetics131(9)1403-21(2012 Sep)
Kennedy RB,Ovsyannikova IG,Pankratz VS,Haralambieva IH,Vierkant RA,Poland GA

Analysis of GWAS top hits in ADHD suggests association to two polymorphisms located in genes expressed in the cerebellum.
American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics153B(6)1127-33(2010 Sep)
Lantieri F,Glessner JT,Hakonarson H,Elia J,Devoto M

Association of the NPAS3 gene and five other loci with response to the antipsychotic iloperidone identified in a whole genome association study.
Molecular psychiatry14(8)804-19(2009 Aug)
Lavedan C,Licamele L,Volpi S,Hamilton J,Heaton C,Mack K,Lannan R,Thompson A,Wolfgang CD,Polymeropoulos MH

Applicability of a genetic signature for enhanced iloperidone efficacy in the treatment of schizophrenia.
The Journal of clinical psychiatry70(6)801-9(2009 Jun)
Volpi S,Potkin SG,Malhotra AK,Licamele L,Lavedan C

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XKR4 cDNA ORF clone, Homo sapiens(human)

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ORF Insert Sequence:

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ORF Insert Sequence:

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