LMTK3 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	LMTK3
Entrez Gene ID	114783
Full Name	lemur tyrosine kinase 3
Synonyms	LMR3,PPP1R101,TYKLM3
General protein information	Preferred Names lemur tyrosine kinase 3 Names serine/threonine-protein kinase LMTK3 protein phosphatase 1, regulatory subunit 101
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 19 Map Location: 19q13.33

mRNA and Protein(s)

mRNA	Protein	Name
XM_011526411.2	XP_011524713.1	serine/threonine-protein kinase LMTK3 isoform X1
XM_011526412.2	XP_011524714.1	serine/threonine-protein kinase LMTK3 isoform X2
NM_001080434.1	NP_001073903.1	serine/threonine-protein kinase LMTK3

Pathways from BioSystems

Homologies

Homo sapiens (human)	LMTK3	NP_001073903.1
Bos taurus (cattle)	LMTK3	XP_002695242.3
Rattus norvegicus (Norway rat)	LOC691056	XP_006229275.1
Xenopus tropicalis (tropical clawed frog)	lmtk3	XP_002935029.2
Mus musculus (house mouse)	Lmtk3	NP_001005511.2
Canis lupus familiaris (dog)	LMTK3	XP_005616921.1
Pan troglodytes (chimpanzee)	LMTK3	XP_003954437.1

Gene Ontology
Bibliography

Related articles in PubMed

LMTK3 knockdown retards cell growth and invasion and promotes apoptosis in thyroid cancer.
Lu L, Yuan X, Zhang Q, Zhang H, Shen B
Molecular medicine reports15(4)2015-2022(2017 Apr)

Phosphorylation of Rab-coupling protein by LMTK3 controls Rab14-dependent EphA2 trafficking to promote cell:cell repulsion.
Gundry C, Marco S, Rainero E, Miller B, Dornier E, Mitchell L, Caswell PT, Campbell AD, Hogeweg A, Sansom OJ, Morton JP, Norman JC
Nature communications814646(2017 Mar)

Lemur Tyrosine Kinase-3 Suppresses Growth of Prostate Cancer Via the AKT and MAPK Signaling Pathways.
Sun P, Sun X, Zhao W, Ren M, Zhang C, Wang Z, Xu W
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology42(6)2582-2592(2017)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The serum LMTK3 level was significantly increased in 102 thyroid carcinoma patients compared with 52 benign thyroid tumor patients and 50 healthy volunteers (P=0.001). The protein and mRNA expression of LMTK3 was markedly higher in thyroid cancer patients compared with patients with benign thyroid tumors. LMTK3 knockdown retarded proliferation, invasion and migration in SW579 cells.
Title: LMTK3 knockdown retards cell growth and invasion and promotes apoptosis in thyroid cancer.

LMTK-3 increased phosphorylated p38 and JNK, but decreased phosphorylated ERK1/2 and AKT. Overexpression of LMTKs may contribute to biologic behavior changes of PCa, especially cell apoptosis.
Title: Lemur Tyrosine Kinase-3 Suppresses Growth of Prostate Cancer Via the AKT and MAPK Signaling Pathways.

LMTK3 escapes tumour suppressor miRNAs via sequestration of DDX5.
Title: LMTK3 escapes tumour suppressor miRNAs via sequestration of DDX5.

LMTK3 functions at distal regions in tethering the chromatin to the nuclear periphery, resulting in H3K9me3 modification and gene silencing.
Title: LMTK3 Represses Tumor Suppressor-like Genes through Chromatin Remodeling in Breast Cancer.

The serum LMTK3 level was significantly increased in human non-small cell lung cancer, and could be used as a potential and valuable biomarker
Title: Serum lemur tyrosine kinase-3: a novel biomarker for screening primary non-small cell lung cancer and predicting cancer progression.

The following LMTK3 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the LMTK3 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu28003	NM_001080434.1 Latest version!	Homo sapiens lemur tyrosine kinase 3 (LMTK3), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$659.50-$923.30 $1319.00
OHu74763	XM_011526411.2 Latest version!	Homo sapiens lemur tyrosine kinase 3 (LMTK3), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$727.30 $1039.00
OHu74764	XM_011526412.2 Latest version!	Homo sapiens lemur tyrosine kinase 3 (LMTK3), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$727.30 $1039.00

ORF Online Only Promotion

Next-day Shipping ORF Clones ( in default vector with tag)
1 Clone	30% OFF
2-4 Clone	40% OFF
5 or more Clone	50% OFF
All Other ORF Clones
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*Business Day

** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

LMTK3 ( NM_001080434.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001073903.1 Homo sapiens lemur tyrosine kinase 3 (LMTK3), mRNA.

Price & Availability↑

CloneID	OHu28003
Clone ID Related Accession (Same CDS sequence)	NM_001080434.1
Accession Version	NM_001080434.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 4470bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-04-30
Organism	Homo sapiens(human)
Product	serine/threonine-protein kinase LMTK3
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC008403.8. On Jan 18, 2007 this sequence version replaced XM_055866.8. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AB067470.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## ##RefSeq-Attributes-START## RefSeq Select criteria :: based on conservation, expression, longest protein ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGAGGCAAG TGCTGTGGTT GTGTAATGTC TGCGTAACCG CACGGGAAAC CCGCCACCAC 
CTCCACCTCC CTGCCATCCT CGACAAGATG CCTGCCCCCG GCGCCCTCAT CCTCCTTGCG 
GCCGTCTCCG CCTCCGGCTG CCTGGCGTCC CCGGCCCACC CCGATGGATT CGCCCTGGGC 
CGGGCTCCTC TGGCTCCTCC CTACGCTGTG GTCCTCATTT CCTGCTCCGG CCTGCTGGCC 
TTCATCTTCC TCCTCCTCAC CTGTCTGTGC TGCAAACGGG GCGATGTCGG CTTCAAGGAA 
TTTGAGAACC CTGAAGGGGA GGACTGCTCC GGGGAGTACA CTCCCCCTGC GGAGGAGACC 
TCCTCCTCAC AGTCGCTGCC TGATGTCTAC ATTCTCCCGC TGGCTGAGGT CTCCCTGCCA 
ATGCCTGCCC CGCAGCCTTC ACACTCAGAC ATGACCACCC CCCTGGGCCT TAGCCGGCAG 
CACCTGAGCT ACCTGCAGGA GATTGGGAGT GGCTGGTTTG GGAAGGTGAT CCTGGGAGAG 
ATTTTCTCCG ACTACACCCC CGCCCAGGTG GTGGTGAAGG AGCTCCGAGC CAGCGCGGGG 
CCCCTGGAGC AACGCAAGTT CATCTCGGAA GCACAGCCGT ACAGGAGCCT GCAGCACCCC 
AATGTCCTCC AGTGCCTGGG TCTGTGCGTG GAGACGCTGC CGTTTCTGCT GATTATGGAG 
TTCTGTCAAC TGGGGGACCT GAAGCGTTAC CTCCGAGCCC AGCGGCCCCC CGAGGGCCTG 
TCCCCTGAGC TACCCCCTCG AGACCTGCGG ACGCTGCAGA GGATGGGCCT GGAGATCGCC 
CGCGGGCTGG CGCACCTGCA TTCCCACAAC TACGTGCACA GCGACCTGGC CCTGCGCAAC 
TGCCTGCTGA CCTCTGACCT GACCGTGCGC ATCGGAGACT ACGGGCTGGC CCACAGCAAC 
TACAAGGAGG ACTACTACCT GACCCCAGAG CGCCTGTGGA TCCCACTGCG CTGGGCGGCG 
CCCGAGCTCC TCGGGGAGCT CCACGGGACC TTCATGGTGG TGGACCAGAG CCGCGAGAGC 
AACATCTGGT CCCTGGGGGT GACCCTGTGG GAGCTGTTTG AGTTTGGGGC CCAGCCCTAC 
CGCCACCTGT CAGACGAGGA GGTCCTCGCC TTCGTGGTCC GCCAGCAGCA TGTGAAGCTG 
GCCCGGCCGA GGCTCAAGCT GCCTTACGCG GACTACTGGT ATGACATTCT TCAGTCCTGC 
TGGCGGCCAC CTGCCCAGCG CCCTTCAGCC TCTGATCTCC AATTGCAGCT CACCTACTTG 
CTCTCCGAGC GGCCTCCCCG GCCCCCACCG CCGCCACCCC CACCCCGAGA CGGTCCCTTC 
CCCTGGCCCT GGCCCCCTGC ACACAGTGCG CCCCGCCCGG GGACCCTCTC CTCACCGTTC 
CCCCTACTGG ATGGCTTCCC TGGAGCCGAC CCCGACGATG TGCTCACGGT CACCGAGAGT 
AGCCGCGGCC TCAACCTCGA GTGCCTGTGG GAGAAGGCCC GGCGTGGGGC CGGCCGGGGT 
GGGGGGGCAC CTGCCTGGCA GCCGGCGTCG GCCCCCCCGG CCCCCCACGC CAACCCCTCC 
AACCCTTTCT ACGAGGCGCT GTCCACGCCC AGCGTGCTGC CTGTCATCAG CGCCCGCAGC 
CCCTCCGTGA GCAGCGAGTA CTACATCCGC TTGGAGGAGC ACGGCTCCCC TCCTGAGCCC 
CTCTTCCCCA ACGACTGGGA CCCCCTGGAC CCAGGAGTGC CCGCCCCTCA GGCCCCCCAG 
GCCCCCTCCG AGGTCCCCCA GCTGGTGTCC GAGACCTGGG CCTCCCCCCT CTTCCCTGCG 
CCCCGGCCCT TCCCAGCCCA GTCCTCAGCG TCAGGCAGCT TCCTGCTGAG CGGCTGGGAC 
CCCGAGGGCC GGGGCGCCGG GGAGACCCTG GCGGGAGACC CTGCCGAGGT CTTGGGGGAG 
CGGGGGACCG CCCCGTGGGT GGAAGAAGAA GAGGAGGAGG AGGAGGGCAG CTCCCCAGGG 
GAAGACAGCA GCAGCCTTGG AGGTGGCCCA AGCCGCCGGG GTCCCCTACC CTGTCCCCTG 
TGCAGCCGCG AGGGGGCCTG CTCCTGCCTG CCACTGGAGC GGGGGGACGC CGTAGCAGGC 
TGGGGAGGCC ACCCTGCTCT TGGCTGCCCC CACCCCCCCG AGGACGACTC CTCGCTGCGG 
GCAGAGCGGG GCTCCCTGGC CGACTTGCCC ATGGCCCCCC CCGCCTCGGC CCCCCCCGAG 
TTTCTGGACC CCCTCATGGG GGCGGCGGCG CCCCAGTACC CCGGGCGGGG GCCACCTCCC 
GCTCCCCCCC CCCCGCCGCC ACCTCCTCGG GCCCCCGCGG ACCCGGCCGC GTCCCCCGAC 
CCCCCTTCGG CCGTGGCCAG TCCCGGTTCA GGCCTCTCGT CGCCGGGCCC CAAGCCGGGG 
GACAGCGGCT ACGAGACCGA GACCCCTTTT TCCCCAGAGG GAGCCTTCCC AGGTGGGGGG 
GCGGCCGAGG AGGAAGGGGT CCCTCGGCCG CGGGCTCCCC CCGAGCCACC CGACCCAGGA 
GCGCCCCGGC CACCTCCAGA CCCGGGTCCG CTCCCACTCC CGGGGCCCCG GGAGAAGCCG 
ACCTTCGTGG TTCAAGTGAG CACGGAACAG CTGCTGATGT CCCTGCGGGA GGATGTGACA 
AGGAACCTCC TGGGGGAGAA GGGGGCGACA GCCCGGGAGA CAGGACCCAG GAAGGCGGGG 
AGAGGCCCCG GGAACAGAGA GAAAGTCCCG GGCCTGAACA GGGACCCGAC AGTCCTGGGC 
AACGGGAAAC AAGCCCCAAG CCTGAGCCTC CCAGTGAACG GGGTGACAGT GCTGGAGAAC 
GGGGACCAGA GAGCCCCAGG CATCGAGGAG AAGGCGGCGG AGAATGGGGC CCTGGGGTCC 
CCCGAGAGAG AAGAGAAAGT GCTGGAGAAT GGGGAGCTGA CACCCCCAAG GAGGGAGGAG 
AAAGCGCTGG AGAATGGGGA GCTGAGGTCC CCAGAGGCCG GGGAGAAGGT GCTGGTGAAT 
GGGGGCCTGA CACCCCCAAA GAGCGAGGAC AAGGTGTCAG AGAATGGGGG CCTGAGATTC 
CCCAGGAACA CGGAGAGGCC ACCAGAGACT GGGCCTTGGA GAGCCCCAGG GCCCTGGGAG 
AAGACGCCCG AGAGTTGGGG TCCAGCCCCC ACGATCGGGG AGCCAGCCCC AGAGACCTCT 
CTGGAGAGAG CCCCTGCACC CAGCGCAGTG GTCTCCTCCC GGAACGGCGG GGAGACAGCC 
CCTGGCCCCC TTGGCCCAGC CCCCAAGAAC GGGACGCTGG AACCCGGGAC CGAGAGGAGA 
GCCCCCGAGA CTGGGGGGGC GCCGAGAGCC CCAGGGGCTG GGAGGCTGGA CCTCGGGAGT 
GGGGGCCGAG CCCCAGTGGG CACGGGGACG GCCCCCGGCG GCGGCCCCGG AAGCGGCGTG 
GACGCAAAGG CCGGATGGGT AGACAACACG AGGCCGCAGC CACCGCCGCC ACCGCTGCCA 
CCGCCACCGG AGGCACAGCC GAGGAGGCTG GAGCCAGCGC CCCCGAGAGC CAGGCCGGAG 
GTGGCCCCCG AGGGAGAGCC CGGGGCCCCA GACAGCAGGG CCGGCGGAGA CACGGCACTC 
AGCGGAGACG GGGACCCCCC CAAGCCCGAG AGGAAGGGCC CCGAGATGCC ACGACTATTC 
TTGGACTTGG GACCCCCTCA GGGGAACAGC GAGCAGATCA AAGCCAGGCT CTCCCGGCTC 
TCGCTGGCGC TGCCGCCGCT CACGCTCACG CCATTCCCGG GGCCGGGCCC GCGGCGGCCC 
CCGTGGGAGG GCGCGGACGC CGGGGCGGCT GGCGGGGAGG CCGGCGGGGC GGGAGCGCCG 
GGGCCGGCGG AGGAGGACGG GGAGGACGAG GACGAGGACG AGGAGGAGGA CGAGGAGGCG 
GCGGCGCCGG GCGCGGCGGC GGGGCCGCGG GGCCCCGGGA GGGCGCGAGC AGCCCCGGTG 
CCCGTCGTGG TGAGCAGCGC CGACGCGGAC GCGGCCCGCC CGCTGCGGGG GCTGCTCAAG 
TCTCCGCGCG GGGCCGACGA GCCAGAGGAC AGCGAGCTGG AGAGGAAGCG CAAGATGGTC 
TCCTTCCACG GGGACGTGAC CGTCTACCTC TTCGACCAGG AGACGCCAAC CAACGAGCTG 
AGCGTCCAGG CCCCCCCCGA GGGGGACACG GACCCGTCAA CGCCTCCAGC GCCCCCGACA 
CCTCCCCACC CCGCCACCCC CGGAGATGGG TTTCCCAGCA ACGACAGCGG CTTTGGAGGC 
AGTTTCGAGT GGGCGGAGGA TTTCCCCCTC CTCCCCCCTC CAGGCCCCCC GCTGTGCTTC 
TCCCGCTTCT CCGTCTCGCC TGCGCTGGAG ACCCCGGGGC CACCCGCCCG GGCCCCCGAC 
GCCCGGCCCG CAGGCCCCGT GGAGAATTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001073903.1
CDS	1..4470
Translation	MRQVLWLCNVCVTARETRHHLHLPAILDKMPAPGALILLAAVSASGCLASPAHPDGFALGRAPLAPPYAVVLISCSGLLAFIFLLLTCLCCKRGDVGFKEFENPEGEDCSGEYTPPAEETSSSQSLPDVYILPLAEVSLPMPAPQPSHSDMTTPLGLSRQHLSYLQEIGSGWFGKVILGEIFSDYTPAQVVVKELRASAGPLEQRKFISEAQPYRSLQHPNVLQCLGLCVETLPFLLIMEFCQLGDLKRYLRAQRPPEGLSPELPPRDLRTLQRMGLEIARGLAHLHSHNYVHSDLALRNCLLTSDLTVRIGDYGLAHSNYKEDYYLTPERLWIPLRWAAPELLGELHGTFMVVDQSRESNIWSLGVTLWELFEFGAQPYRHLSDEEVLAFVVRQQHVKLARPRLKLPYADYWYDILQSCWRPPAQRPSASDLQLQLTYLLSERPPRPPPPPPPPRDGPFPWPWPPAHSAPRPGTLSSPFPLLDGFPGADPDDVLTVTESSRGLNLECLWEKARRGAGRGGGAPAWQPASAPPAPHANPSNPFYEALSTPSVLPVISARSPSVSSEYYIRLEEHGSPPEPLFPNDWDPLDPGVPAPQAPQAPSEVPQLVSETWASPLFPAPRPFPAQSSASGSFLLSGWDPEGRGAGETLAGDPAEVLGERGTAPWVEEEEEEEEGSSPGEDSSSLGGGPSRRGPLPCPLCSREGACSCLPLERGDAVAGWGGHPALGCPHPPEDDSSLRAERGSLADLPMAPPASAPPEFLDPLMGAAAPQYPGRGPPPAPPPPPPPPRAPADPAASPDPPSAVASPGSGLSSPGPKPGDSGYETETPFSPEGAFPGGGAAEEEGVPRPRAPPEPPDPGAPRPPPDPGPLPLPGPREKPTFVVQVSTEQLLMSLREDVTRNLLGEKGATARETGPRKAGRGPGNREKVPGLNRDPTVLGNGKQAPSLSLPVNGVTVLENGDQRAPGIEEKAAENGALGSPEREEKVLENGELTPPRREEKALENGELRSPEAGEKVLVNGGLTPPKSEDKVSENGGLRFPRNTERPPETGPWRAPGPWEKTPESWGPAPTIGEPAPETSLERAPAPSAVVSSRNGGETAPGPLGPAPKNGTLEPGTERRAPETGGAPRAPGAGRLDLGSGGRAPVGTGTAPGGGPGSGVDAKAGWVDNTRPQPPPPPLPPPPEAQPRRLEPAPPRARPEVAPEGEPGAPDSRAGGDTALSGDGDPPKPERKGPEMPRLFLDLGPPQGNSEQIKARLSRLSLALPPLTLTPFPGPGPRRPPWEGADAGAAGGEAGGAGAPGPAEEDGEDEDEDEEEDEEAAAPGAAAGPRGPGRARAAPVPVVVSSADADAARPLRGLLKSPRGADEPEDSELERKRKMVSFHGDVTVYLFDQETPTNELSVQAPPEGDTDPSTPPAPPTPPHPATPGDGFPSNDSGFGGSFEWAEDFPLLPPPGPPLCFSRFSVSPALETPGPPARAPDARPAGPVEN

Target ORF information:

RefSeq Version	NM_001080434.1
Organism	Homo sapiens(human)
Definition	Homo sapiens lemur tyrosine kinase 3 (LMTK3), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001080434.1

ORF Insert Sequence:

ATGAGGCAAG TGCTGTGGTT GTGTAATGTC TGCGTAACCG CACGGGAAAC CCGCCACCAC 
CTCCACCTCC CTGCCATCCT CGACAAGATG CCTGCCCCCG GCGCCCTCAT CCTCCTTGCG 
GCCGTCTCCG CCTCCGGCTG CCTGGCGTCC CCGGCCCACC CCGATGGATT CGCCCTGGGC 
CGGGCTCCTC TGGCTCCTCC CTACGCTGTG GTCCTCATTT CCTGCTCCGG CCTGCTGGCC 
TTCATCTTCC TCCTCCTCAC CTGTCTGTGC TGCAAACGGG GCGATGTCGG CTTCAAGGAA 
TTTGAGAACC CTGAAGGGGA GGACTGCTCC GGGGAGTACA CTCCCCCTGC GGAGGAGACC 
TCCTCCTCAC AGTCGCTGCC TGATGTCTAC ATTCTCCCGC TGGCTGAGGT CTCCCTGCCA 
ATGCCTGCCC CGCAGCCTTC ACACTCAGAC ATGACCACCC CCCTGGGCCT TAGCCGGCAG 
CACCTGAGCT ACCTGCAGGA GATTGGGAGT GGCTGGTTTG GGAAGGTGAT CCTGGGAGAG 
ATTTTCTCCG ACTACACCCC CGCCCAGGTG GTGGTGAAGG AGCTCCGAGC CAGCGCGGGG 
CCCCTGGAGC AACGCAAGTT CATCTCGGAA GCACAGCCGT ACAGGAGCCT GCAGCACCCC 
AATGTCCTCC AGTGCCTGGG TCTGTGCGTG GAGACGCTGC CGTTTCTGCT GATTATGGAG 
TTCTGTCAAC TGGGGGACCT GAAGCGTTAC CTCCGAGCCC AGCGGCCCCC CGAGGGCCTG 
TCCCCTGAGC TACCCCCTCG AGACCTGCGG ACGCTGCAGA GGATGGGCCT GGAGATCGCC 
CGCGGGCTGG CGCACCTGCA TTCCCACAAC TACGTGCACA GCGACCTGGC CCTGCGCAAC 
TGCCTGCTGA CCTCTGACCT GACCGTGCGC ATCGGAGACT ACGGGCTGGC CCACAGCAAC 
TACAAGGAGG ACTACTACCT GACCCCAGAG CGCCTGTGGA TCCCACTGCG CTGGGCGGCG 
CCCGAGCTCC TCGGGGAGCT CCACGGGACC TTCATGGTGG TGGACCAGAG CCGCGAGAGC 
AACATCTGGT CCCTGGGGGT GACCCTGTGG GAGCTGTTTG AGTTTGGGGC CCAGCCCTAC 
CGCCACCTGT CAGACGAGGA GGTCCTCGCC TTCGTGGTCC GCCAGCAGCA TGTGAAGCTG 
GCCCGGCCGA GGCTCAAGCT GCCTTACGCG GACTACTGGT ATGACATTCT TCAGTCCTGC 
TGGCGGCCAC CTGCCCAGCG CCCTTCAGCC TCTGATCTCC AATTGCAGCT CACCTACTTG 
CTCTCCGAGC GGCCTCCCCG GCCCCCACCG CCGCCACCCC CACCCCGAGA CGGTCCCTTC 
CCCTGGCCCT GGCCCCCTGC ACACAGTGCG CCCCGCCCGG GGACCCTCTC CTCACCGTTC 
CCCCTACTGG ATGGCTTCCC TGGAGCCGAC CCCGACGATG TGCTCACGGT CACCGAGAGT 
AGCCGCGGCC TCAACCTCGA GTGCCTGTGG GAGAAGGCCC GGCGTGGGGC CGGCCGGGGT 
GGGGGGGCAC CTGCCTGGCA GCCGGCGTCG GCCCCCCCGG CCCCCCACGC CAACCCCTCC 
AACCCTTTCT ACGAGGCGCT GTCCACGCCC AGCGTGCTGC CTGTCATCAG CGCCCGCAGC 
CCCTCCGTGA GCAGCGAGTA CTACATCCGC TTGGAGGAGC ACGGCTCCCC TCCTGAGCCC 
CTCTTCCCCA ACGACTGGGA CCCCCTGGAC CCAGGAGTGC CCGCCCCTCA GGCCCCCCAG 
GCCCCCTCCG AGGTCCCCCA GCTGGTGTCC GAGACCTGGG CCTCCCCCCT CTTCCCTGCG 
CCCCGGCCCT TCCCAGCCCA GTCCTCAGCG TCAGGCAGCT TCCTGCTGAG CGGCTGGGAC 
CCCGAGGGCC GGGGCGCCGG GGAGACCCTG GCGGGAGACC CTGCCGAGGT CTTGGGGGAG 
CGGGGGACCG CCCCGTGGGT GGAAGAAGAA GAGGAGGAGG AGGAGGGCAG CTCCCCAGGG 
GAAGACAGCA GCAGCCTTGG AGGTGGCCCA AGCCGCCGGG GTCCCCTACC CTGTCCCCTG 
TGCAGCCGCG AGGGGGCCTG CTCCTGCCTG CCACTGGAGC GGGGGGACGC CGTAGCAGGC 
TGGGGAGGCC ACCCTGCTCT TGGCTGCCCC CACCCCCCCG AGGACGACTC CTCGCTGCGG 
GCAGAGCGGG GCTCCCTGGC CGACTTGCCC ATGGCCCCCC CCGCCTCGGC CCCCCCCGAG 
TTTCTGGACC CCCTCATGGG GGCGGCGGCG CCCCAGTACC CCGGGCGGGG GCCACCTCCC 
GCTCCCCCCC CCCCGCCGCC ACCTCCTCGG GCCCCCGCGG ACCCGGCCGC GTCCCCCGAC 
CCCCCTTCGG CCGTGGCCAG TCCCGGTTCA GGCCTCTCGT CGCCGGGCCC CAAGCCGGGG 
GACAGCGGCT ACGAGACCGA GACCCCTTTT TCCCCAGAGG GAGCCTTCCC AGGTGGGGGG 
GCGGCCGAGG AGGAAGGGGT CCCTCGGCCG CGGGCTCCCC CCGAGCCACC CGACCCAGGA 
GCGCCCCGGC CACCTCCAGA CCCGGGTCCG CTCCCACTCC CGGGGCCCCG GGAGAAGCCG 
ACCTTCGTGG TTCAAGTGAG CACGGAACAG CTGCTGATGT CCCTGCGGGA GGATGTGACA 
AGGAACCTCC TGGGGGAGAA GGGGGCGACA GCCCGGGAGA CAGGACCCAG GAAGGCGGGG 
AGAGGCCCCG GGAACAGAGA GAAAGTCCCG GGCCTGAACA GGGACCCGAC AGTCCTGGGC 
AACGGGAAAC AAGCCCCAAG CCTGAGCCTC CCAGTGAACG GGGTGACAGT GCTGGAGAAC 
GGGGACCAGA GAGCCCCAGG CATCGAGGAG AAGGCGGCGG AGAATGGGGC CCTGGGGTCC 
CCCGAGAGAG AAGAGAAAGT GCTGGAGAAT GGGGAGCTGA CACCCCCAAG GAGGGAGGAG 
AAAGCGCTGG AGAATGGGGA GCTGAGGTCC CCAGAGGCCG GGGAGAAGGT GCTGGTGAAT 
GGGGGCCTGA CACCCCCAAA GAGCGAGGAC AAGGTGTCAG AGAATGGGGG CCTGAGATTC 
CCCAGGAACA CGGAGAGGCC ACCAGAGACT GGGCCTTGGA GAGCCCCAGG GCCCTGGGAG 
AAGACGCCCG AGAGTTGGGG TCCAGCCCCC ACGATCGGGG AGCCAGCCCC AGAGACCTCT 
CTGGAGAGAG CCCCTGCACC CAGCGCAGTG GTCTCCTCCC GGAACGGCGG GGAGACAGCC 
CCTGGCCCCC TTGGCCCAGC CCCCAAGAAC GGGACGCTGG AACCCGGGAC CGAGAGGAGA 
GCCCCCGAGA CTGGGGGGGC GCCGAGAGCC CCAGGGGCTG GGAGGCTGGA CCTCGGGAGT 
GGGGGCCGAG CCCCAGTGGG CACGGGGACG GCCCCCGGCG GCGGCCCCGG AAGCGGCGTG 
GACGCAAAGG CCGGATGGGT AGACAACACG AGGCCGCAGC CACCGCCGCC ACCGCTGCCA 
CCGCCACCGG AGGCACAGCC GAGGAGGCTG GAGCCAGCGC CCCCGAGAGC CAGGCCGGAG 
GTGGCCCCCG AGGGAGAGCC CGGGGCCCCA GACAGCAGGG CCGGCGGAGA CACGGCACTC 
AGCGGAGACG GGGACCCCCC CAAGCCCGAG AGGAAGGGCC CCGAGATGCC ACGACTATTC 
TTGGACTTGG GACCCCCTCA GGGGAACAGC GAGCAGATCA AAGCCAGGCT CTCCCGGCTC 
TCGCTGGCGC TGCCGCCGCT CACGCTCACG CCATTCCCGG GGCCGGGCCC GCGGCGGCCC 
CCGTGGGAGG GCGCGGACGC CGGGGCGGCT GGCGGGGAGG CCGGCGGGGC GGGAGCGCCG 
GGGCCGGCGG AGGAGGACGG GGAGGACGAG GACGAGGACG AGGAGGAGGA CGAGGAGGCG 
GCGGCGCCGG GCGCGGCGGC GGGGCCGCGG GGCCCCGGGA GGGCGCGAGC AGCCCCGGTG 
CCCGTCGTGG TGAGCAGCGC CGACGCGGAC GCGGCCCGCC CGCTGCGGGG GCTGCTCAAG 
TCTCCGCGCG GGGCCGACGA GCCAGAGGAC AGCGAGCTGG AGAGGAAGCG CAAGATGGTC 
TCCTTCCACG GGGACGTGAC CGTCTACCTC TTCGACCAGG AGACGCCAAC CAACGAGCTG 
AGCGTCCAGG CCCCCCCCGA GGGGGACACG GACCCGTCAA CGCCTCCAGC GCCCCCGACA 
CCTCCCCACC CCGCCACCCC CGGAGATGGG TTTCCCAGCA ACGACAGCGG CTTTGGAGGC 
AGTTTCGAGT GGGCGGAGGA TTTCCCCCTC CTCCCCCCTC CAGGCCCCCC GCTGTGCTTC 
TCCCGCTTCT CCGTCTCGCC TGCGCTGGAG ACCCCGGGGC CACCCGCCCG GGCCCCCGAC 
GCCCGGCCCG CAGGCCCCGT GGAGAATTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

LMTK3 ( XM_011526411.2 ) cDNA ORF clone, Homo sapiens(human) -> XP_011524713.1 Homo sapiens lemur tyrosine kinase 3 (LMTK3), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OHu74763
Clone ID Related Accession (Same CDS sequence)	XM_011526411.2
Accession Version	XM_011526411.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 4461bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	serine/threonine-protein kinase LMTK3 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000019.10) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 6, 2016 this sequence version replaced XM_011526411.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGAGAGGT CCGCGCCCAG GGTGGGAGTC CGCGCTTCCG GCCGCCACCA CCTCCACCTC 
CCTGCCATCC TCGACAAGAT GCCTGCCCCC GGCGCCCTCA TCCTCCTTGC GGCCGTCTCC 
GCCTCCGGCT GCCTGGCGTC CCCGGCCCAC CCCGATGGAT TCGCCCTGGG CCGGGCTCCT 
CTGGCTCCTC CCTACGCTGT GGTCCTCATT TCCTGCTCCG GCCTGCTGGC CTTCATCTTC 
CTCCTCCTCA CCTGTCTGTG CTGCAAACGG GGCGATGTCG GCTTCAAGGA ATTTGAGAAC 
CCTGAAGGGG AGGACTGCTC CGGGGAGTAC ACTCCCCCTG CGGAGGAGAC CTCCTCCTCA 
CAGTCGCTGC CTGATGTCTA CATTCTCCCG CTGGCTGAGG TCTCCCTGCC AATGCCTGCC 
CCGCAGCCTT CACACTCAGA CATGACCACC CCCCTGGGCC TTAGCCGGCA GCACCTGAGC 
TACCTGCAGG AGATTGGGAG TGGCTGGTTT GGGAAGGTGA TCCTGGGAGA GATTTTCTCC 
GACTACACCC CCGCCCAGGT GGTGGTGAAG GAGCTCCGAG CCAGCGCGGG GCCCCTGGAG 
CAACGCAAGT TCATCTCGGA AGCACAGCCG TACAGGAGCC TGCAGCACCC CAATGTCCTC 
CAGTGCCTGG GTCTGTGCGT GGAGACGCTG CCGTTTCTGC TGATTATGGA GTTCTGTCAA 
CTGGGGGACC TGAAGCGTTA CCTCCGAGCC CAGCGGCCCC CCGAGGGCCT GTCCCCTGAG 
CTACCCCCTC GAGACCTGCG GACGCTGCAG AGGATGGGCC TGGAGATCGC CCGCGGGCTG 
GCGCACCTGC ATTCCCACAA CTACGTGCAC AGCGACCTGG CCCTGCGCAA CTGCCTGCTG 
ACCTCTGACC TGACCGTGCG CATCGGAGAC TACGGGCTGG CCCACAGCAA CTACAAGGAG 
GACTACTACC TGACCCCAGA GCGCCTGTGG ATCCCACTGC GCTGGGCGGC GCCCGAGCTC 
CTCGGGGAGC TCCACGGGAC CTTCATGGTG GTGGACCAGA GCCGCGAGAG CAACATCTGG 
TCCCTGGGGG TGACCCTGTG GGAGCTGTTT GAGTTTGGGG CCCAGCCCTA CCGCCACCTG 
TCAGACGAGG AGGTCCTCGC CTTCGTGGTC CGCCAGCAGC ATGTGAAGCT GGCCCGGCCG 
AGGCTCAAGC TGCCTTACGC GGACTACTGG TATGACATTC TTCAGTCCTG CTGGCGGCCA 
CCTGCCCAGC GCCCTTCAGC CTCTGATCTC CAATTGCAGC TCACCTACTT GCTCTCCGAG 
CGGCCTCCCC GGCCCCCACC GCCGCCACCC CCACCCCGAG ACGGTCCCTT CCCCTGGCCC 
TGGCCCCCTG CACACAGTGC GCCCCGCCCG GGGACCCTCT CCTCACCGTT CCCCCTACTG 
GATGGCTTCC CTGGAGCCGA CCCCGACGAT GTGCTCACGG TCACCGAGAG TAGCCGCGGC 
CTCAACCTCG AGTGCCTGTG GGAGAAGGCC CGGCGTGGGG CCGGCCGGGG TGGGGGGGCA 
CCTGCCTGGC AGCCGGCGTC GGCCCCCCCG GCCCCCCACG CCAACCCCTC CAACCCTTTC 
TACGAGGCGC TGTCCACGCC CAGCGTGCTG CCTGTCATCA GCGCCCGCAG CCCCTCCGTG 
AGCAGCGAGT ACTACATCCG CTTGGAGGAG CACGGCTCCC CTCCTGAGCC CCTCTTCCCC 
AACGACTGGG ACCCCCTGGA CCCAGGAGTG CCCGCCCCTC AGGCCCCCCA GGCCCCCTCC 
GAGGTCCCCC AGCTGGTGTC CGAGACCTGG GCCTCCCCCC TCTTCCCTGC GCCCCGGCCC 
TTCCCAGCCC AGTCCTCAGC GTCAGGCAGC TTCCTGCTGA GCGGCTGGGA CCCCGAGGGC 
CGGGGCGCCG GGGAGACCCT GGCGGGAGAC CCTGCCGAGG TCTTGGGGGA GCGGGGGACC 
GCCCCGTGGG TGGAAGAAGA AGAGGAGGAG GAGGAGGGCA GCTCCCCAGG GGAAGACAGC 
AGCAGCCTTG GAGGTGGCCC AAGCCGCCGG GGTCCCCTAC CCTGTCCCCT GTGCAGCCGC 
GAGGGGGCCT GCTCCTGCCT GCCACTGGAG CGGGGGGACG CCGTAGCAGG CTGGGGAGGC 
CACCCTGCTC TTGGCTGCCC CCACCCCCCC GAGGACGACT CCTCGCTGCG GGCAGAGCGG 
GGCTCCCTGG CCGACTTGCC CATGGCCCCC CCCGCCTCGG CCCCCCCCGA GTTTCTGGAC 
CCCCTCATGG GGGCGGCGGC GCCCCAGTAC CCCGGGCGGG GGCCACCTCC CGCTCCCCCC 
CCCCCGCCGC CACCTCCTCG GGCCCCCGCG GACCCGGCCG CGTCCCCCGA CCCCCCTTCG 
GCCGTGGCCA GTCCCGGTTC AGGCCTCTCG TCGCCGGGCC CCAAGCCGGG GGACAGCGGC 
TACGAGACCG AGACCCCTTT TTCCCCAGAG GGAGCCTTCC CAGGTGGGGG GGCGGCCGAG 
GAGGAAGGGG TCCCTCGGCC GCGGGCTCCC CCCGAGCCAC CCGACCCAGG AGCGCCCCGG 
CCACCTCCAG ACCCGGGTCC GCTCCCACTC CCGGGGCCCC GGGAGAAGCC GACCTTCGTG 
GTTCAAGTGA GCACGGAACA GCTGCTGATG TCCCTGCGGG AGGATGTGAC AAGGAACCTC 
CTGGGGGAGA AGGGGGCGAC AGCCCGGGAG ACAGGACCCA GGAAGGCGGG GAGAGGCCCC 
GGGAACAGAG AGAAAGTCCC GGGCCTGAAC AGGGACCCGA CAGTCCTGGG CAACGGGAAA 
CAAGCCCCAA GCCTGAGCCT CCCAGTGAAC GGGGTGACAG TGCTGGAGAA CGGGGACCAG 
AGAGCCCCAG GCATCGAGGA GAAGGCGGCG GAGAATGGGG CCCTGGGGTC CCCCGAGAGA 
GAAGAGAAAG TGCTGGAGAA TGGGGAGCTG ACACCCCCAA GGAGGGAGGA GAAAGCGCTG 
GAGAATGGGG AGCTGAGGTC CCCAGAGGCC GGGGAGAAGG TGCTGGTGAA TGGGGGCCTG 
ACACCCCCAA AGAGCGAGGA CAAGGTGTCA GAGAATGGGG GCCTGAGATT CCCCAGGAAC 
ACGGAGAGGC CACCAGAGAC TGGGCCTTGG AGAGCCCCAG GGCCCTGGGA GAAGACGCCC 
GAGAGTTGGG GTCCAGCCCC CACGATCGGG GAGCCAGCCC CAGAGACCTC TCTGGAGAGA 
GCCCCTGCAC CCAGCGCAGT GGTCTCCTCC CGGAACGGCG GGGAGACAGC CCCTGGCCCC 
CTTGGCCCAG CCCCCAAGAA CGGGACGCTG GAACCCGGGA CCGAGAGGAG AGCCCCCGAG 
ACTGGGGGGG CGCCGAGAGC CCCAGGGGCT GGGAGGCTGG ACCTCGGGAG TGGGGGCCGA 
GCCCCAGTGG GCACGGGGAC GGCCCCCGGC GGCGGCCCCG GAAGCGGCGT GGACGCAAAG 
GCCGGATGGG TAGACAACAC GAGGCCGCAG CCACCGCCGC CACCGCTGCC ACCGCCACCG 
GAGGCACAGC CGAGGAGGCT GGAGCCAGCG CCCCCGAGAG CCAGGCCGGA GGTGGCCCCC 
GAGGGAGAGC CCGGGGCCCC AGACAGCAGG GCCGGCGGAG ACACGGCACT CAGCGGAGAC 
GGGGACCCCC CCAAGCCCGA GAGGAAGGGC CCCGAGATGC CACGACTATT CTTGGACTTG 
GGACCCCCTC AGGGGAACAG CGAGCAGATC AAAGCCAGGC TCTCCCGGCT CTCGCTGGCG 
CTGCCGCCGC TCACGCTCAC GCCATTCCCG GGGCCGGGCC CGCGGCGGCC CCCGTGGGAG 
GGCGCGGACG CCGGGGCGGC TGGCGGGGAG GCCGGCGGGG CGGGAGCGCC GGGGCCGGCG 
GAGGAGGACG GGGAGGACGA GGACGAGGAC GAGGAGGAGG ACGAGGAGGC GGCGGCGCCG 
GGCGCGGCGG CGGGGCCGCG GGGCCCCGGG AGGGCGCGAG CAGCCCCGGT GCCCGTCGTG 
GTGAGCAGCG CCGACGCGGA CGCGGCCCGC CCGCTGCGGG GGCTGCTCAA GTCTCCGCGC 
GGGGCCGACG AGCCAGAGGA CAGCGAGCTG GAGAGGAAGC GCAAGATGGT CTCCTTCCAC 
GGGGACGTGA CCGTCTACCT CTTCGACCAG GAGACGCCAA CCAACGAGCT GAGCGTCCAG 
GCCCCCCCCG AGGGGGACAC GGACCCGTCA ACGCCTCCAG CGCCCCCGAC ACCTCCCCAC 
CCCGCCACCC CCGGAGATGG GTTTCCCAGC AACGACAGCG GCTTTGGAGG CAGTTTCGAG 
TGGGCGGAGG ATTTCCCCCT CCTCCCCCCT CCAGGCCCCC CGCTGTGCTT CTCCCGCTTC 
TCCGTCTCGC CTGCGCTGGA GACCCCGGGG CCACCCGCCC GGGCCCCCGA CGCCCGGCCC 
GCAGGCCCCG TGGAGAATTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_011524713.1
CDS	341..4801
Translation	MERSAPRVGVRASGRHHLHLPAILDKMPAPGALILLAAVSASGCLASPAHPDGFALGRAPLAPPYAVVLISCSGLLAFIFLLLTCLCCKRGDVGFKEFENPEGEDCSGEYTPPAEETSSSQSLPDVYILPLAEVSLPMPAPQPSHSDMTTPLGLSRQHLSYLQEIGSGWFGKVILGEIFSDYTPAQVVVKELRASAGPLEQRKFISEAQPYRSLQHPNVLQCLGLCVETLPFLLIMEFCQLGDLKRYLRAQRPPEGLSPELPPRDLRTLQRMGLEIARGLAHLHSHNYVHSDLALRNCLLTSDLTVRIGDYGLAHSNYKEDYYLTPERLWIPLRWAAPELLGELHGTFMVVDQSRESNIWSLGVTLWELFEFGAQPYRHLSDEEVLAFVVRQQHVKLARPRLKLPYADYWYDILQSCWRPPAQRPSASDLQLQLTYLLSERPPRPPPPPPPPRDGPFPWPWPPAHSAPRPGTLSSPFPLLDGFPGADPDDVLTVTESSRGLNLECLWEKARRGAGRGGGAPAWQPASAPPAPHANPSNPFYEALSTPSVLPVISARSPSVSSEYYIRLEEHGSPPEPLFPNDWDPLDPGVPAPQAPQAPSEVPQLVSETWASPLFPAPRPFPAQSSASGSFLLSGWDPEGRGAGETLAGDPAEVLGERGTAPWVEEEEEEEEGSSPGEDSSSLGGGPSRRGPLPCPLCSREGACSCLPLERGDAVAGWGGHPALGCPHPPEDDSSLRAERGSLADLPMAPPASAPPEFLDPLMGAAAPQYPGRGPPPAPPPPPPPPRAPADPAASPDPPSAVASPGSGLSSPGPKPGDSGYETETPFSPEGAFPGGGAAEEEGVPRPRAPPEPPDPGAPRPPPDPGPLPLPGPREKPTFVVQVSTEQLLMSLREDVTRNLLGEKGATARETGPRKAGRGPGNREKVPGLNRDPTVLGNGKQAPSLSLPVNGVTVLENGDQRAPGIEEKAAENGALGSPEREEKVLENGELTPPRREEKALENGELRSPEAGEKVLVNGGLTPPKSEDKVSENGGLRFPRNTERPPETGPWRAPGPWEKTPESWGPAPTIGEPAPETSLERAPAPSAVVSSRNGGETAPGPLGPAPKNGTLEPGTERRAPETGGAPRAPGAGRLDLGSGGRAPVGTGTAPGGGPGSGVDAKAGWVDNTRPQPPPPPLPPPPEAQPRRLEPAPPRARPEVAPEGEPGAPDSRAGGDTALSGDGDPPKPERKGPEMPRLFLDLGPPQGNSEQIKARLSRLSLALPPLTLTPFPGPGPRRPPWEGADAGAAGGEAGGAGAPGPAEEDGEDEDEDEEEDEEAAAPGAAAGPRGPGRARAAPVPVVVSSADADAARPLRGLLKSPRGADEPEDSELERKRKMVSFHGDVTVYLFDQETPTNELSVQAPPEGDTDPSTPPAPPTPPHPATPGDGFPSNDSGFGGSFEWAEDFPLLPPPGPPLCFSRFSVSPALETPGPPARAPDARPAGPVEN

Target ORF information:

RefSeq Version	XM_011526411.2
Organism	Homo sapiens(human)
Definition	Homo sapiens lemur tyrosine kinase 3 (LMTK3), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011526411.2

ORF Insert Sequence:

ATGGAGAGGT CCGCGCCCAG GGTGGGAGTC CGCGCTTCCG GCCGCCACCA CCTCCACCTC 
CCTGCCATCC TCGACAAGAT GCCTGCCCCC GGCGCCCTCA TCCTCCTTGC GGCCGTCTCC 
GCCTCCGGCT GCCTGGCGTC CCCGGCCCAC CCCGATGGAT TCGCCCTGGG CCGGGCTCCT 
CTGGCTCCTC CCTACGCTGT GGTCCTCATT TCCTGCTCCG GCCTGCTGGC CTTCATCTTC 
CTCCTCCTCA CCTGTCTGTG CTGCAAACGG GGCGATGTCG GCTTCAAGGA ATTTGAGAAC 
CCTGAAGGGG AGGACTGCTC CGGGGAGTAC ACTCCCCCTG CGGAGGAGAC CTCCTCCTCA 
CAGTCGCTGC CTGATGTCTA CATTCTCCCG CTGGCTGAGG TCTCCCTGCC AATGCCTGCC 
CCGCAGCCTT CACACTCAGA CATGACCACC CCCCTGGGCC TTAGCCGGCA GCACCTGAGC 
TACCTGCAGG AGATTGGGAG TGGCTGGTTT GGGAAGGTGA TCCTGGGAGA GATTTTCTCC 
GACTACACCC CCGCCCAGGT GGTGGTGAAG GAGCTCCGAG CCAGCGCGGG GCCCCTGGAG 
CAACGCAAGT TCATCTCGGA AGCACAGCCG TACAGGAGCC TGCAGCACCC CAATGTCCTC 
CAGTGCCTGG GTCTGTGCGT GGAGACGCTG CCGTTTCTGC TGATTATGGA GTTCTGTCAA 
CTGGGGGACC TGAAGCGTTA CCTCCGAGCC CAGCGGCCCC CCGAGGGCCT GTCCCCTGAG 
CTACCCCCTC GAGACCTGCG GACGCTGCAG AGGATGGGCC TGGAGATCGC CCGCGGGCTG 
GCGCACCTGC ATTCCCACAA CTACGTGCAC AGCGACCTGG CCCTGCGCAA CTGCCTGCTG 
ACCTCTGACC TGACCGTGCG CATCGGAGAC TACGGGCTGG CCCACAGCAA CTACAAGGAG 
GACTACTACC TGACCCCAGA GCGCCTGTGG ATCCCACTGC GCTGGGCGGC GCCCGAGCTC 
CTCGGGGAGC TCCACGGGAC CTTCATGGTG GTGGACCAGA GCCGCGAGAG CAACATCTGG 
TCCCTGGGGG TGACCCTGTG GGAGCTGTTT GAGTTTGGGG CCCAGCCCTA CCGCCACCTG 
TCAGACGAGG AGGTCCTCGC CTTCGTGGTC CGCCAGCAGC ATGTGAAGCT GGCCCGGCCG 
AGGCTCAAGC TGCCTTACGC GGACTACTGG TATGACATTC TTCAGTCCTG CTGGCGGCCA 
CCTGCCCAGC GCCCTTCAGC CTCTGATCTC CAATTGCAGC TCACCTACTT GCTCTCCGAG 
CGGCCTCCCC GGCCCCCACC GCCGCCACCC CCACCCCGAG ACGGTCCCTT CCCCTGGCCC 
TGGCCCCCTG CACACAGTGC GCCCCGCCCG GGGACCCTCT CCTCACCGTT CCCCCTACTG 
GATGGCTTCC CTGGAGCCGA CCCCGACGAT GTGCTCACGG TCACCGAGAG TAGCCGCGGC 
CTCAACCTCG AGTGCCTGTG GGAGAAGGCC CGGCGTGGGG CCGGCCGGGG TGGGGGGGCA 
CCTGCCTGGC AGCCGGCGTC GGCCCCCCCG GCCCCCCACG CCAACCCCTC CAACCCTTTC 
TACGAGGCGC TGTCCACGCC CAGCGTGCTG CCTGTCATCA GCGCCCGCAG CCCCTCCGTG 
AGCAGCGAGT ACTACATCCG CTTGGAGGAG CACGGCTCCC CTCCTGAGCC CCTCTTCCCC 
AACGACTGGG ACCCCCTGGA CCCAGGAGTG CCCGCCCCTC AGGCCCCCCA GGCCCCCTCC 
GAGGTCCCCC AGCTGGTGTC CGAGACCTGG GCCTCCCCCC TCTTCCCTGC GCCCCGGCCC 
TTCCCAGCCC AGTCCTCAGC GTCAGGCAGC TTCCTGCTGA GCGGCTGGGA CCCCGAGGGC 
CGGGGCGCCG GGGAGACCCT GGCGGGAGAC CCTGCCGAGG TCTTGGGGGA GCGGGGGACC 
GCCCCGTGGG TGGAAGAAGA AGAGGAGGAG GAGGAGGGCA GCTCCCCAGG GGAAGACAGC 
AGCAGCCTTG GAGGTGGCCC AAGCCGCCGG GGTCCCCTAC CCTGTCCCCT GTGCAGCCGC 
GAGGGGGCCT GCTCCTGCCT GCCACTGGAG CGGGGGGACG CCGTAGCAGG CTGGGGAGGC 
CACCCTGCTC TTGGCTGCCC CCACCCCCCC GAGGACGACT CCTCGCTGCG GGCAGAGCGG 
GGCTCCCTGG CCGACTTGCC CATGGCCCCC CCCGCCTCGG CCCCCCCCGA GTTTCTGGAC 
CCCCTCATGG GGGCGGCGGC GCCCCAGTAC CCCGGGCGGG GGCCACCTCC CGCTCCCCCC 
CCCCCGCCGC CACCTCCTCG GGCCCCCGCG GACCCGGCCG CGTCCCCCGA CCCCCCTTCG 
GCCGTGGCCA GTCCCGGTTC AGGCCTCTCG TCGCCGGGCC CCAAGCCGGG GGACAGCGGC 
TACGAGACCG AGACCCCTTT TTCCCCAGAG GGAGCCTTCC CAGGTGGGGG GGCGGCCGAG 
GAGGAAGGGG TCCCTCGGCC GCGGGCTCCC CCCGAGCCAC CCGACCCAGG AGCGCCCCGG 
CCACCTCCAG ACCCGGGTCC GCTCCCACTC CCGGGGCCCC GGGAGAAGCC GACCTTCGTG 
GTTCAAGTGA GCACGGAACA GCTGCTGATG TCCCTGCGGG AGGATGTGAC AAGGAACCTC 
CTGGGGGAGA AGGGGGCGAC AGCCCGGGAG ACAGGACCCA GGAAGGCGGG GAGAGGCCCC 
GGGAACAGAG AGAAAGTCCC GGGCCTGAAC AGGGACCCGA CAGTCCTGGG CAACGGGAAA 
CAAGCCCCAA GCCTGAGCCT CCCAGTGAAC GGGGTGACAG TGCTGGAGAA CGGGGACCAG 
AGAGCCCCAG GCATCGAGGA GAAGGCGGCG GAGAATGGGG CCCTGGGGTC CCCCGAGAGA 
GAAGAGAAAG TGCTGGAGAA TGGGGAGCTG ACACCCCCAA GGAGGGAGGA GAAAGCGCTG 
GAGAATGGGG AGCTGAGGTC CCCAGAGGCC GGGGAGAAGG TGCTGGTGAA TGGGGGCCTG 
ACACCCCCAA AGAGCGAGGA CAAGGTGTCA GAGAATGGGG GCCTGAGATT CCCCAGGAAC 
ACGGAGAGGC CACCAGAGAC TGGGCCTTGG AGAGCCCCAG GGCCCTGGGA GAAGACGCCC 
GAGAGTTGGG GTCCAGCCCC CACGATCGGG GAGCCAGCCC CAGAGACCTC TCTGGAGAGA 
GCCCCTGCAC CCAGCGCAGT GGTCTCCTCC CGGAACGGCG GGGAGACAGC CCCTGGCCCC 
CTTGGCCCAG CCCCCAAGAA CGGGACGCTG GAACCCGGGA CCGAGAGGAG AGCCCCCGAG 
ACTGGGGGGG CGCCGAGAGC CCCAGGGGCT GGGAGGCTGG ACCTCGGGAG TGGGGGCCGA 
GCCCCAGTGG GCACGGGGAC GGCCCCCGGC GGCGGCCCCG GAAGCGGCGT GGACGCAAAG 
GCCGGATGGG TAGACAACAC GAGGCCGCAG CCACCGCCGC CACCGCTGCC ACCGCCACCG 
GAGGCACAGC CGAGGAGGCT GGAGCCAGCG CCCCCGAGAG CCAGGCCGGA GGTGGCCCCC 
GAGGGAGAGC CCGGGGCCCC AGACAGCAGG GCCGGCGGAG ACACGGCACT CAGCGGAGAC 
GGGGACCCCC CCAAGCCCGA GAGGAAGGGC CCCGAGATGC CACGACTATT CTTGGACTTG 
GGACCCCCTC AGGGGAACAG CGAGCAGATC AAAGCCAGGC TCTCCCGGCT CTCGCTGGCG 
CTGCCGCCGC TCACGCTCAC GCCATTCCCG GGGCCGGGCC CGCGGCGGCC CCCGTGGGAG 
GGCGCGGACG CCGGGGCGGC TGGCGGGGAG GCCGGCGGGG CGGGAGCGCC GGGGCCGGCG 
GAGGAGGACG GGGAGGACGA GGACGAGGAC GAGGAGGAGG ACGAGGAGGC GGCGGCGCCG 
GGCGCGGCGG CGGGGCCGCG GGGCCCCGGG AGGGCGCGAG CAGCCCCGGT GCCCGTCGTG 
GTGAGCAGCG CCGACGCGGA CGCGGCCCGC CCGCTGCGGG GGCTGCTCAA GTCTCCGCGC 
GGGGCCGACG AGCCAGAGGA CAGCGAGCTG GAGAGGAAGC GCAAGATGGT CTCCTTCCAC 
GGGGACGTGA CCGTCTACCT CTTCGACCAG GAGACGCCAA CCAACGAGCT GAGCGTCCAG 
GCCCCCCCCG AGGGGGACAC GGACCCGTCA ACGCCTCCAG CGCCCCCGAC ACCTCCCCAC 
CCCGCCACCC CCGGAGATGG GTTTCCCAGC AACGACAGCG GCTTTGGAGG CAGTTTCGAG 
TGGGCGGAGG ATTTCCCCCT CCTCCCCCCT CCAGGCCCCC CGCTGTGCTT CTCCCGCTTC 
TCCGTCTCGC CTGCGCTGGA GACCCCGGGG CCACCCGCCC GGGCCCCCGA CGCCCGGCCC 
GCAGGCCCCG TGGAGAATTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

LMTK3 ( XM_011526412.2 ) cDNA ORF clone, Homo sapiens(human) -> XP_011524714.1 Homo sapiens lemur tyrosine kinase 3 (LMTK3), transcript variant X2, mRNA.

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CloneID	OHu74764
Clone ID Related Accession (Same CDS sequence)	XM_011526412.2
Accession Version	XM_011526412.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 4428bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	serine/threonine-protein kinase LMTK3 isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000019.10) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 6, 2016 this sequence version replaced XM_011526412.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGAGAGCC GCCACCACCT CCACCTCCCT GCCATCCTCG ACAAGATGCC TGCCCCCGGC 
GCCCTCATCC TCCTTGCGGC CGTCTCCGCC TCCGGCTGCC TGGCGTCCCC GGCCCACCCC 
GATGGATTCG CCCTGGGCCG GGCTCCTCTG GCTCCTCCCT ACGCTGTGGT CCTCATTTCC 
TGCTCCGGCC TGCTGGCCTT CATCTTCCTC CTCCTCACCT GTCTGTGCTG CAAACGGGGC 
GATGTCGGCT TCAAGGAATT TGAGAACCCT GAAGGGGAGG ACTGCTCCGG GGAGTACACT 
CCCCCTGCGG AGGAGACCTC CTCCTCACAG TCGCTGCCTG ATGTCTACAT TCTCCCGCTG 
GCTGAGGTCT CCCTGCCAAT GCCTGCCCCG CAGCCTTCAC ACTCAGACAT GACCACCCCC 
CTGGGCCTTA GCCGGCAGCA CCTGAGCTAC CTGCAGGAGA TTGGGAGTGG CTGGTTTGGG 
AAGGTGATCC TGGGAGAGAT TTTCTCCGAC TACACCCCCG CCCAGGTGGT GGTGAAGGAG 
CTCCGAGCCA GCGCGGGGCC CCTGGAGCAA CGCAAGTTCA TCTCGGAAGC ACAGCCGTAC 
AGGAGCCTGC AGCACCCCAA TGTCCTCCAG TGCCTGGGTC TGTGCGTGGA GACGCTGCCG 
TTTCTGCTGA TTATGGAGTT CTGTCAACTG GGGGACCTGA AGCGTTACCT CCGAGCCCAG 
CGGCCCCCCG AGGGCCTGTC CCCTGAGCTA CCCCCTCGAG ACCTGCGGAC GCTGCAGAGG 
ATGGGCCTGG AGATCGCCCG CGGGCTGGCG CACCTGCATT CCCACAACTA CGTGCACAGC 
GACCTGGCCC TGCGCAACTG CCTGCTGACC TCTGACCTGA CCGTGCGCAT CGGAGACTAC 
GGGCTGGCCC ACAGCAACTA CAAGGAGGAC TACTACCTGA CCCCAGAGCG CCTGTGGATC 
CCACTGCGCT GGGCGGCGCC CGAGCTCCTC GGGGAGCTCC ACGGGACCTT CATGGTGGTG 
GACCAGAGCC GCGAGAGCAA CATCTGGTCC CTGGGGGTGA CCCTGTGGGA GCTGTTTGAG 
TTTGGGGCCC AGCCCTACCG CCACCTGTCA GACGAGGAGG TCCTCGCCTT CGTGGTCCGC 
CAGCAGCATG TGAAGCTGGC CCGGCCGAGG CTCAAGCTGC CTTACGCGGA CTACTGGTAT 
GACATTCTTC AGTCCTGCTG GCGGCCACCT GCCCAGCGCC CTTCAGCCTC TGATCTCCAA 
TTGCAGCTCA CCTACTTGCT CTCCGAGCGG CCTCCCCGGC CCCCACCGCC GCCACCCCCA 
CCCCGAGACG GTCCCTTCCC CTGGCCCTGG CCCCCTGCAC ACAGTGCGCC CCGCCCGGGG 
ACCCTCTCCT CACCGTTCCC CCTACTGGAT GGCTTCCCTG GAGCCGACCC CGACGATGTG 
CTCACGGTCA CCGAGAGTAG CCGCGGCCTC AACCTCGAGT GCCTGTGGGA GAAGGCCCGG 
CGTGGGGCCG GCCGGGGTGG GGGGGCACCT GCCTGGCAGC CGGCGTCGGC CCCCCCGGCC 
CCCCACGCCA ACCCCTCCAA CCCTTTCTAC GAGGCGCTGT CCACGCCCAG CGTGCTGCCT 
GTCATCAGCG CCCGCAGCCC CTCCGTGAGC AGCGAGTACT ACATCCGCTT GGAGGAGCAC 
GGCTCCCCTC CTGAGCCCCT CTTCCCCAAC GACTGGGACC CCCTGGACCC AGGAGTGCCC 
GCCCCTCAGG CCCCCCAGGC CCCCTCCGAG GTCCCCCAGC TGGTGTCCGA GACCTGGGCC 
TCCCCCCTCT TCCCTGCGCC CCGGCCCTTC CCAGCCCAGT CCTCAGCGTC AGGCAGCTTC 
CTGCTGAGCG GCTGGGACCC CGAGGGCCGG GGCGCCGGGG AGACCCTGGC GGGAGACCCT 
GCCGAGGTCT TGGGGGAGCG GGGGACCGCC CCGTGGGTGG AAGAAGAAGA GGAGGAGGAG 
GAGGGCAGCT CCCCAGGGGA AGACAGCAGC AGCCTTGGAG GTGGCCCAAG CCGCCGGGGT 
CCCCTACCCT GTCCCCTGTG CAGCCGCGAG GGGGCCTGCT CCTGCCTGCC ACTGGAGCGG 
GGGGACGCCG TAGCAGGCTG GGGAGGCCAC CCTGCTCTTG GCTGCCCCCA CCCCCCCGAG 
GACGACTCCT CGCTGCGGGC AGAGCGGGGC TCCCTGGCCG ACTTGCCCAT GGCCCCCCCC 
GCCTCGGCCC CCCCCGAGTT TCTGGACCCC CTCATGGGGG CGGCGGCGCC CCAGTACCCC 
GGGCGGGGGC CACCTCCCGC TCCCCCCCCC CCGCCGCCAC CTCCTCGGGC CCCCGCGGAC 
CCGGCCGCGT CCCCCGACCC CCCTTCGGCC GTGGCCAGTC CCGGTTCAGG CCTCTCGTCG 
CCGGGCCCCA AGCCGGGGGA CAGCGGCTAC GAGACCGAGA CCCCTTTTTC CCCAGAGGGA 
GCCTTCCCAG GTGGGGGGGC GGCCGAGGAG GAAGGGGTCC CTCGGCCGCG GGCTCCCCCC 
GAGCCACCCG ACCCAGGAGC GCCCCGGCCA CCTCCAGACC CGGGTCCGCT CCCACTCCCG 
GGGCCCCGGG AGAAGCCGAC CTTCGTGGTT CAAGTGAGCA CGGAACAGCT GCTGATGTCC 
CTGCGGGAGG ATGTGACAAG GAACCTCCTG GGGGAGAAGG GGGCGACAGC CCGGGAGACA 
GGACCCAGGA AGGCGGGGAG AGGCCCCGGG AACAGAGAGA AAGTCCCGGG CCTGAACAGG 
GACCCGACAG TCCTGGGCAA CGGGAAACAA GCCCCAAGCC TGAGCCTCCC AGTGAACGGG 
GTGACAGTGC TGGAGAACGG GGACCAGAGA GCCCCAGGCA TCGAGGAGAA GGCGGCGGAG 
AATGGGGCCC TGGGGTCCCC CGAGAGAGAA GAGAAAGTGC TGGAGAATGG GGAGCTGACA 
CCCCCAAGGA GGGAGGAGAA AGCGCTGGAG AATGGGGAGC TGAGGTCCCC AGAGGCCGGG 
GAGAAGGTGC TGGTGAATGG GGGCCTGACA CCCCCAAAGA GCGAGGACAA GGTGTCAGAG 
AATGGGGGCC TGAGATTCCC CAGGAACACG GAGAGGCCAC CAGAGACTGG GCCTTGGAGA 
GCCCCAGGGC CCTGGGAGAA GACGCCCGAG AGTTGGGGTC CAGCCCCCAC GATCGGGGAG 
CCAGCCCCAG AGACCTCTCT GGAGAGAGCC CCTGCACCCA GCGCAGTGGT CTCCTCCCGG 
AACGGCGGGG AGACAGCCCC TGGCCCCCTT GGCCCAGCCC CCAAGAACGG GACGCTGGAA 
CCCGGGACCG AGAGGAGAGC CCCCGAGACT GGGGGGGCGC CGAGAGCCCC AGGGGCTGGG 
AGGCTGGACC TCGGGAGTGG GGGCCGAGCC CCAGTGGGCA CGGGGACGGC CCCCGGCGGC 
GGCCCCGGAA GCGGCGTGGA CGCAAAGGCC GGATGGGTAG ACAACACGAG GCCGCAGCCA 
CCGCCGCCAC CGCTGCCACC GCCACCGGAG GCACAGCCGA GGAGGCTGGA GCCAGCGCCC 
CCGAGAGCCA GGCCGGAGGT GGCCCCCGAG GGAGAGCCCG GGGCCCCAGA CAGCAGGGCC 
GGCGGAGACA CGGCACTCAG CGGAGACGGG GACCCCCCCA AGCCCGAGAG GAAGGGCCCC 
GAGATGCCAC GACTATTCTT GGACTTGGGA CCCCCTCAGG GGAACAGCGA GCAGATCAAA 
GCCAGGCTCT CCCGGCTCTC GCTGGCGCTG CCGCCGCTCA CGCTCACGCC ATTCCCGGGG 
CCGGGCCCGC GGCGGCCCCC GTGGGAGGGC GCGGACGCCG GGGCGGCTGG CGGGGAGGCC 
GGCGGGGCGG GAGCGCCGGG GCCGGCGGAG GAGGACGGGG AGGACGAGGA CGAGGACGAG 
GAGGAGGACG AGGAGGCGGC GGCGCCGGGC GCGGCGGCGG GGCCGCGGGG CCCCGGGAGG 
GCGCGAGCAG CCCCGGTGCC CGTCGTGGTG AGCAGCGCCG ACGCGGACGC GGCCCGCCCG 
CTGCGGGGGC TGCTCAAGTC TCCGCGCGGG GCCGACGAGC CAGAGGACAG CGAGCTGGAG 
AGGAAGCGCA AGATGGTCTC CTTCCACGGG GACGTGACCG TCTACCTCTT CGACCAGGAG 
ACGCCAACCA ACGAGCTGAG CGTCCAGGCC CCCCCCGAGG GGGACACGGA CCCGTCAACG 
CCTCCAGCGC CCCCGACACC TCCCCACCCC GCCACCCCCG GAGATGGGTT TCCCAGCAAC 
GACAGCGGCT TTGGAGGCAG TTTCGAGTGG GCGGAGGATT TCCCCCTCCT CCCCCCTCCA 
GGCCCCCCGC TGTGCTTCTC CCGCTTCTCC GTCTCGCCTG CGCTGGAGAC CCCGGGGCCA 
CCCGCCCGGG CCCCCGACGC CCGGCCCGCA GGCCCCGTGG AGAATTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_011524714.1
CDS	341..4768
Translation	MESRHHLHLPAILDKMPAPGALILLAAVSASGCLASPAHPDGFALGRAPLAPPYAVVLISCSGLLAFIFLLLTCLCCKRGDVGFKEFENPEGEDCSGEYTPPAEETSSSQSLPDVYILPLAEVSLPMPAPQPSHSDMTTPLGLSRQHLSYLQEIGSGWFGKVILGEIFSDYTPAQVVVKELRASAGPLEQRKFISEAQPYRSLQHPNVLQCLGLCVETLPFLLIMEFCQLGDLKRYLRAQRPPEGLSPELPPRDLRTLQRMGLEIARGLAHLHSHNYVHSDLALRNCLLTSDLTVRIGDYGLAHSNYKEDYYLTPERLWIPLRWAAPELLGELHGTFMVVDQSRESNIWSLGVTLWELFEFGAQPYRHLSDEEVLAFVVRQQHVKLARPRLKLPYADYWYDILQSCWRPPAQRPSASDLQLQLTYLLSERPPRPPPPPPPPRDGPFPWPWPPAHSAPRPGTLSSPFPLLDGFPGADPDDVLTVTESSRGLNLECLWEKARRGAGRGGGAPAWQPASAPPAPHANPSNPFYEALSTPSVLPVISARSPSVSSEYYIRLEEHGSPPEPLFPNDWDPLDPGVPAPQAPQAPSEVPQLVSETWASPLFPAPRPFPAQSSASGSFLLSGWDPEGRGAGETLAGDPAEVLGERGTAPWVEEEEEEEEGSSPGEDSSSLGGGPSRRGPLPCPLCSREGACSCLPLERGDAVAGWGGHPALGCPHPPEDDSSLRAERGSLADLPMAPPASAPPEFLDPLMGAAAPQYPGRGPPPAPPPPPPPPRAPADPAASPDPPSAVASPGSGLSSPGPKPGDSGYETETPFSPEGAFPGGGAAEEEGVPRPRAPPEPPDPGAPRPPPDPGPLPLPGPREKPTFVVQVSTEQLLMSLREDVTRNLLGEKGATARETGPRKAGRGPGNREKVPGLNRDPTVLGNGKQAPSLSLPVNGVTVLENGDQRAPGIEEKAAENGALGSPEREEKVLENGELTPPRREEKALENGELRSPEAGEKVLVNGGLTPPKSEDKVSENGGLRFPRNTERPPETGPWRAPGPWEKTPESWGPAPTIGEPAPETSLERAPAPSAVVSSRNGGETAPGPLGPAPKNGTLEPGTERRAPETGGAPRAPGAGRLDLGSGGRAPVGTGTAPGGGPGSGVDAKAGWVDNTRPQPPPPPLPPPPEAQPRRLEPAPPRARPEVAPEGEPGAPDSRAGGDTALSGDGDPPKPERKGPEMPRLFLDLGPPQGNSEQIKARLSRLSLALPPLTLTPFPGPGPRRPPWEGADAGAAGGEAGGAGAPGPAEEDGEDEDEDEEEDEEAAAPGAAAGPRGPGRARAAPVPVVVSSADADAARPLRGLLKSPRGADEPEDSELERKRKMVSFHGDVTVYLFDQETPTNELSVQAPPEGDTDPSTPPAPPTPPHPATPGDGFPSNDSGFGGSFEWAEDFPLLPPPGPPLCFSRFSVSPALETPGPPARAPDARPAGPVEN

Target ORF information:

RefSeq Version	XM_011526412.2
Organism	Homo sapiens(human)
Definition	Homo sapiens lemur tyrosine kinase 3 (LMTK3), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011526412.2

ORF Insert Sequence:

ATGGAGAGCC GCCACCACCT CCACCTCCCT GCCATCCTCG ACAAGATGCC TGCCCCCGGC 
GCCCTCATCC TCCTTGCGGC CGTCTCCGCC TCCGGCTGCC TGGCGTCCCC GGCCCACCCC 
GATGGATTCG CCCTGGGCCG GGCTCCTCTG GCTCCTCCCT ACGCTGTGGT CCTCATTTCC 
TGCTCCGGCC TGCTGGCCTT CATCTTCCTC CTCCTCACCT GTCTGTGCTG CAAACGGGGC 
GATGTCGGCT TCAAGGAATT TGAGAACCCT GAAGGGGAGG ACTGCTCCGG GGAGTACACT 
CCCCCTGCGG AGGAGACCTC CTCCTCACAG TCGCTGCCTG ATGTCTACAT TCTCCCGCTG 
GCTGAGGTCT CCCTGCCAAT GCCTGCCCCG CAGCCTTCAC ACTCAGACAT GACCACCCCC 
CTGGGCCTTA GCCGGCAGCA CCTGAGCTAC CTGCAGGAGA TTGGGAGTGG CTGGTTTGGG 
AAGGTGATCC TGGGAGAGAT TTTCTCCGAC TACACCCCCG CCCAGGTGGT GGTGAAGGAG 
CTCCGAGCCA GCGCGGGGCC CCTGGAGCAA CGCAAGTTCA TCTCGGAAGC ACAGCCGTAC 
AGGAGCCTGC AGCACCCCAA TGTCCTCCAG TGCCTGGGTC TGTGCGTGGA GACGCTGCCG 
TTTCTGCTGA TTATGGAGTT CTGTCAACTG GGGGACCTGA AGCGTTACCT CCGAGCCCAG 
CGGCCCCCCG AGGGCCTGTC CCCTGAGCTA CCCCCTCGAG ACCTGCGGAC GCTGCAGAGG 
ATGGGCCTGG AGATCGCCCG CGGGCTGGCG CACCTGCATT CCCACAACTA CGTGCACAGC 
GACCTGGCCC TGCGCAACTG CCTGCTGACC TCTGACCTGA CCGTGCGCAT CGGAGACTAC 
GGGCTGGCCC ACAGCAACTA CAAGGAGGAC TACTACCTGA CCCCAGAGCG CCTGTGGATC 
CCACTGCGCT GGGCGGCGCC CGAGCTCCTC GGGGAGCTCC ACGGGACCTT CATGGTGGTG 
GACCAGAGCC GCGAGAGCAA CATCTGGTCC CTGGGGGTGA CCCTGTGGGA GCTGTTTGAG 
TTTGGGGCCC AGCCCTACCG CCACCTGTCA GACGAGGAGG TCCTCGCCTT CGTGGTCCGC 
CAGCAGCATG TGAAGCTGGC CCGGCCGAGG CTCAAGCTGC CTTACGCGGA CTACTGGTAT 
GACATTCTTC AGTCCTGCTG GCGGCCACCT GCCCAGCGCC CTTCAGCCTC TGATCTCCAA 
TTGCAGCTCA CCTACTTGCT CTCCGAGCGG CCTCCCCGGC CCCCACCGCC GCCACCCCCA 
CCCCGAGACG GTCCCTTCCC CTGGCCCTGG CCCCCTGCAC ACAGTGCGCC CCGCCCGGGG 
ACCCTCTCCT CACCGTTCCC CCTACTGGAT GGCTTCCCTG GAGCCGACCC CGACGATGTG 
CTCACGGTCA CCGAGAGTAG CCGCGGCCTC AACCTCGAGT GCCTGTGGGA GAAGGCCCGG 
CGTGGGGCCG GCCGGGGTGG GGGGGCACCT GCCTGGCAGC CGGCGTCGGC CCCCCCGGCC 
CCCCACGCCA ACCCCTCCAA CCCTTTCTAC GAGGCGCTGT CCACGCCCAG CGTGCTGCCT 
GTCATCAGCG CCCGCAGCCC CTCCGTGAGC AGCGAGTACT ACATCCGCTT GGAGGAGCAC 
GGCTCCCCTC CTGAGCCCCT CTTCCCCAAC GACTGGGACC CCCTGGACCC AGGAGTGCCC 
GCCCCTCAGG CCCCCCAGGC CCCCTCCGAG GTCCCCCAGC TGGTGTCCGA GACCTGGGCC 
TCCCCCCTCT TCCCTGCGCC CCGGCCCTTC CCAGCCCAGT CCTCAGCGTC AGGCAGCTTC 
CTGCTGAGCG GCTGGGACCC CGAGGGCCGG GGCGCCGGGG AGACCCTGGC GGGAGACCCT 
GCCGAGGTCT TGGGGGAGCG GGGGACCGCC CCGTGGGTGG AAGAAGAAGA GGAGGAGGAG 
GAGGGCAGCT CCCCAGGGGA AGACAGCAGC AGCCTTGGAG GTGGCCCAAG CCGCCGGGGT 
CCCCTACCCT GTCCCCTGTG CAGCCGCGAG GGGGCCTGCT CCTGCCTGCC ACTGGAGCGG 
GGGGACGCCG TAGCAGGCTG GGGAGGCCAC CCTGCTCTTG GCTGCCCCCA CCCCCCCGAG 
GACGACTCCT CGCTGCGGGC AGAGCGGGGC TCCCTGGCCG ACTTGCCCAT GGCCCCCCCC 
GCCTCGGCCC CCCCCGAGTT TCTGGACCCC CTCATGGGGG CGGCGGCGCC CCAGTACCCC 
GGGCGGGGGC CACCTCCCGC TCCCCCCCCC CCGCCGCCAC CTCCTCGGGC CCCCGCGGAC 
CCGGCCGCGT CCCCCGACCC CCCTTCGGCC GTGGCCAGTC CCGGTTCAGG CCTCTCGTCG 
CCGGGCCCCA AGCCGGGGGA CAGCGGCTAC GAGACCGAGA CCCCTTTTTC CCCAGAGGGA 
GCCTTCCCAG GTGGGGGGGC GGCCGAGGAG GAAGGGGTCC CTCGGCCGCG GGCTCCCCCC 
GAGCCACCCG ACCCAGGAGC GCCCCGGCCA CCTCCAGACC CGGGTCCGCT CCCACTCCCG 
GGGCCCCGGG AGAAGCCGAC CTTCGTGGTT CAAGTGAGCA CGGAACAGCT GCTGATGTCC 
CTGCGGGAGG ATGTGACAAG GAACCTCCTG GGGGAGAAGG GGGCGACAGC CCGGGAGACA 
GGACCCAGGA AGGCGGGGAG AGGCCCCGGG AACAGAGAGA AAGTCCCGGG CCTGAACAGG 
GACCCGACAG TCCTGGGCAA CGGGAAACAA GCCCCAAGCC TGAGCCTCCC AGTGAACGGG 
GTGACAGTGC TGGAGAACGG GGACCAGAGA GCCCCAGGCA TCGAGGAGAA GGCGGCGGAG 
AATGGGGCCC TGGGGTCCCC CGAGAGAGAA GAGAAAGTGC TGGAGAATGG GGAGCTGACA 
CCCCCAAGGA GGGAGGAGAA AGCGCTGGAG AATGGGGAGC TGAGGTCCCC AGAGGCCGGG 
GAGAAGGTGC TGGTGAATGG GGGCCTGACA CCCCCAAAGA GCGAGGACAA GGTGTCAGAG 
AATGGGGGCC TGAGATTCCC CAGGAACACG GAGAGGCCAC CAGAGACTGG GCCTTGGAGA 
GCCCCAGGGC CCTGGGAGAA GACGCCCGAG AGTTGGGGTC CAGCCCCCAC GATCGGGGAG 
CCAGCCCCAG AGACCTCTCT GGAGAGAGCC CCTGCACCCA GCGCAGTGGT CTCCTCCCGG 
AACGGCGGGG AGACAGCCCC TGGCCCCCTT GGCCCAGCCC CCAAGAACGG GACGCTGGAA 
CCCGGGACCG AGAGGAGAGC CCCCGAGACT GGGGGGGCGC CGAGAGCCCC AGGGGCTGGG 
AGGCTGGACC TCGGGAGTGG GGGCCGAGCC CCAGTGGGCA CGGGGACGGC CCCCGGCGGC 
GGCCCCGGAA GCGGCGTGGA CGCAAAGGCC GGATGGGTAG ACAACACGAG GCCGCAGCCA 
CCGCCGCCAC CGCTGCCACC GCCACCGGAG GCACAGCCGA GGAGGCTGGA GCCAGCGCCC 
CCGAGAGCCA GGCCGGAGGT GGCCCCCGAG GGAGAGCCCG GGGCCCCAGA CAGCAGGGCC 
GGCGGAGACA CGGCACTCAG CGGAGACGGG GACCCCCCCA AGCCCGAGAG GAAGGGCCCC 
GAGATGCCAC GACTATTCTT GGACTTGGGA CCCCCTCAGG GGAACAGCGA GCAGATCAAA 
GCCAGGCTCT CCCGGCTCTC GCTGGCGCTG CCGCCGCTCA CGCTCACGCC ATTCCCGGGG 
CCGGGCCCGC GGCGGCCCCC GTGGGAGGGC GCGGACGCCG GGGCGGCTGG CGGGGAGGCC 
GGCGGGGCGG GAGCGCCGGG GCCGGCGGAG GAGGACGGGG AGGACGAGGA CGAGGACGAG 
GAGGAGGACG AGGAGGCGGC GGCGCCGGGC GCGGCGGCGG GGCCGCGGGG CCCCGGGAGG 
GCGCGAGCAG CCCCGGTGCC CGTCGTGGTG AGCAGCGCCG ACGCGGACGC GGCCCGCCCG 
CTGCGGGGGC TGCTCAAGTC TCCGCGCGGG GCCGACGAGC CAGAGGACAG CGAGCTGGAG 
AGGAAGCGCA AGATGGTCTC CTTCCACGGG GACGTGACCG TCTACCTCTT CGACCAGGAG 
ACGCCAACCA ACGAGCTGAG CGTCCAGGCC CCCCCCGAGG GGGACACGGA CCCGTCAACG 
CCTCCAGCGC CCCCGACACC TCCCCACCCC GCCACCCCCG GAGATGGGTT TCCCAGCAAC 
GACAGCGGCT TTGGAGGCAG TTTCGAGTGG GCGGAGGATT TCCCCCTCCT CCCCCCTCCA 
GGCCCCCCGC TGTGCTTCTC CCGCTTCTCC GTCTCGCCTG CGCTGGAGAC CCCGGGGCCA 
CCCGCCCGGG CCCCCGACGC CCGGCCCGCA GGCCCCGTGG AGAATTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

LMTK3 knockdown retards cell growth and invasion and promotes apoptosis in thyroid cancer.
Molecular medicine reports15(4)2015-2022(2017 Apr)
Lu L,Yuan X,Zhang Q,Zhang H,Shen B

Phosphorylation of Rab-coupling protein by LMTK3 controls Rab14-dependent EphA2 trafficking to promote cell:cell repulsion.
Nature communications814646(2017 Mar)
Gundry C,Marco S,Rainero E,Miller B,Dornier E,Mitchell L,Caswell PT,Campbell AD,Hogeweg A,Sansom OJ,Morton JP,Norman JC

Lemur Tyrosine Kinase-3 Suppresses Growth of Prostate Cancer Via the AKT and MAPK Signaling Pathways.
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology42(6)2582-2592(2017)
Sun P,Sun X,Zhao W,Ren M,Zhang C,Wang Z,Xu W

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LMTK3 cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

見積依頼

Eメール

電話

FAX

オンラインフォーム

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