Gene Symbol | PARK7 |
Entrez Gene ID | 11315 |
Full Name | Parkinsonism associated deglycase |
Synonyms | DJ-1,DJ1,GATD2,HEL-S-67p |
General protein information |
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Gene Type | protein-coding |
Organism | Homo sapiens(human) |
Genome | |
Summary | The product of this gene belongs to the peptidase C56 family of proteins. It acts as a positive regulator of androgen receptor-dependent transcription. It may also function as a redox-sensitive chaperone, as a sensor for oxidative stress, and it apparently protects neurons against oxidative stress and cell death. Defects in this gene are the cause of autosomal recessive early-onset Parkinson disease 7. Two transcript variants encoding the same protein have been identified for this gene. [provided by RefSeq, Jul 2008]. |
Disorder MIM: | |
Disorder Html: | Parkinson disease 7, autosomal recessive early-onset, 606324 (3) |