HRH3 cDNA ORF clone, Homo sapiens(Human)

Gene
Clones
gRNAs

Summary

Gene Symbol	HRH3
Entrez Gene ID	11255
Full Name	histamine receptor H3
Synonyms	GPCR97,HH3R
General protein information	Preferred Names histamine receptor H3 Names histamine H3 receptor G protein-coupled receptor 97 H3R
Gene Type	protein-coding
Organism	Homo sapiens(Human)
Genome	Chromosome: 20 Map Location: 20q13.33
Summary	Histamine is a ubiquitous messenger molecule released from mast cells, enterochromaffin-like cells, and neurons. Its various actions are mediated by histamine receptors H1, H2, H3 and H4. This gene encodes one of the histamine receptors (H3) which belongs to the family 1 of G protein-coupled receptors. It is an integral membrane protein and can regulate neurotransmitter release. This receptor can also increase voltage-dependent calcium current in smooth muscles and innervates the blood vessels and the heart in cardiovascular system. [provided by RefSeq, Jul 2008].
Disorder MIM:	604525

mRNA and Protein(s)

mRNA	Protein	Name
XM_017027623.1	XP_016883112.1	histamine H3 receptor isoform X2
NM_007232.2	NP_009163.2	histamine H3 receptor
NM_007232.3	NP_009163.2	histamine H3 receptor
XM_005260266.3	XP_005260323.1	histamine H3 receptor isoform X1
XM_005260266.2	XP_005260323.1	histamine H3 receptor isoform X1
XM_005260267.3	XP_005260324.1	histamine H3 receptor isoform X2

Pathways from BioSystems

Homologies

Homo sapiens (human)	HRH3	NP_009163.2
Canis lupus familiaris (dog)	HRH3	XP_005635315.1
Danio rerio (zebrafish)	LOC100334962	XP_003200969.1
Xenopus tropicalis (tropical clawed frog)	hrh3	XP_002939863.2
Mus musculus (house mouse)	Hrh3	NP_598610.1
Rattus norvegicus (Norway rat)	Hrh3	NP_445958.1
Gallus gallus (chicken)	HRH3	XP_004947140.1
	HRH3	NP_001028070.1
Bos taurus (cattle)	HRH3	XP_002692304.2
Danio rerio (zebrafish)	LOC100331077	XP_002667517.1

Gene Ontology
Bibliography

Related articles in PubMed

The naturally occurring mutation Y197C does not affect the expression or signaling of the human histamine H
Flores-Clemente C, Escamilla-S?nchez J, Arias JM, Arias-Monta?o JA
Neuroscience letters64177-80(2017 Feb)

Histamine Receptor 3 negatively regulates oligodendrocyte differentiation and remyelination.
Chen Y, Zhen W, Guo T, Zhao Y, Liu A, Rubio JP, Krull D, Richardson JC, Lu H, Wang R
PloS one12(12)e0189380(2017)

Associations of Polymorphisms in HRH2, HRH3, DAO, and HNMT Genes with Risk of Chronic Heart Failure.
He GH, Cai WK, Zhang JB, Ma CY, Yan F, Lu J, Xu GL
BioMed research international20161208476(2016)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

We detected high H3R expression in oligodendroglial cells from demyelination lesions in human samples of patients with MS, and validated a genetic association between an exonic single nucleotide polymorphism in HRH3 and susceptibility to multiple sclerosis.
Title: Histamine Receptor 3 negatively regulates oligodendrocyte differentiation and remyelination.

Decrease in histamine H3 receptor function was linked to epileptic activity in the hippocampus and temporal neocortex of patients with pharmacoresistant mesial temporal lobe epilepsy.
Title: Pharmacoresistant temporal lobe epilepsy modifies histamine turnover and H3 receptor function in the human hippocampus and temporal neocortex.

These findings for the first time screen out one SNP (rs3787429) of HRH3 gene that was significantly associated with CHF in Chinese Han population
Title: Associations of Polymorphisms in HRH2, HRH3, DAO, and HNMT Genes with Risk of Chronic Heart Failure.

Molecular modelling studies, including molecular dynamic simulations and calculation of Gibbs energy of solvation of hH3R and hH4R, were studied.
Title: Sodium binding to hH3R and hH 4R--a molecular modeling study.

The polymorphisms of HNMT and HRH3 were irrelevant with breast cancer in the present study.
Title: Associations of polymorphisms in histidine decarboxylase, histamine N-methyltransferase and histamine receptor H3 genes with breast cancer.

The following HRH3 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the HRH3 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu24367	NM_007232.3 Latest version!	Homo sapiens histamine receptor H3 (HRH3), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$159.50-$223.30 $319.00
OHu92899	XM_017027623.1 Latest version!	Homo sapiens histamine receptor H3 (HRH3), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$223.30 $319.00
OHu52880	XM_005260266.3 Latest version!	Homo sapiens histamine receptor H3 (HRH3), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$223.30 $319.00
OHu52882	XM_005260267.3 Latest version!	Homo sapiens histamine receptor H3 (HRH3), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$223.30 $319.00
View Old Accession Versions >>
OHu24367	NM_007232.2	Homo sapiens histamine receptor H3 (HRH3), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$159.50-$223.30 $319.00
OHu52880	XM_005260266.2	Homo sapiens histamine receptor H3 (HRH3), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$223.30 $319.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

HRH3 ( NM_007232.2 ) cDNA ORF clone, Homo sapiens(Human) -> NP_009163.2 Homo sapiens histamine receptor H3 (HRH3), mRNA.

Price & Availability↑

CloneID	OHu24367
Clone ID Related Accession (Same CDS sequence)	NM_007232.2 , NM_007232.3
Accession Version	NM_007232.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1338bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-12-26
Organism	Homo sapiens(human)
Product	histamine H3 receptor
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AL078633.32. On Jul 10, 2008 this sequence version replaced NM_007232.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AF140538.1, AF321910.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2144335, SAMEA2145743 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGAGCGCG CGCCGCCCGA CGGGCCGCTG AACGCTTCGG GGGCGCTGGC GGGCGAGGCG 
GCGGCGGCGG GCGGGGCGCG CGGCTTCTCG GCAGCCTGGA CCGCGGTGCT GGCCGCGCTC 
ATGGCGCTGC TCATCGTGGC CACGGTGCTG GGCAACGCGC TGGTCATGCT CGCCTTCGTG 
GCCGACTCGA GCCTCCGCAC CCAGAACAAC TTCTTCCTGC TCAACCTCGC CATCTCCGAC 
TTCCTCGTCG GCGCCTTCTG CATCCCACTG TATGTACCCT ACGTGCTGAC AGGCCGCTGG 
ACCTTCGGCC GGGGCCTCTG CAAGCTGTGG CTGGTAGTGG ACTACCTGCT GTGCACCTCC 
TCTGCCTTCA ACATCGTGCT CATCAGCTAC GACCGCTTCC TGTCGGTCAC CCGAGCGGTC 
TCATACCGGG CCCAGCAGGG TGACACGCGG CGGGCAGTGC GGAAGATGCT GCTGGTGTGG 
GTGCTGGCCT TCCTGCTGTA CGGACCAGCC ATCCTGAGCT GGGAGTACCT GTCCGGGGGC 
AGCTCCATCC CCGAGGGCCA CTGCTATGCC GAGTTCTTCT ACAACTGGTA CTTCCTCATC 
ACGGCTTCCA CCCTGGAGTT CTTTACGCCC TTCCTCAGCG TCACCTTCTT TAACCTCAGC 
ATCTACCTGA ACATCCAGAG GCGCACCCGC CTCCGGCTGG ATGGGGCTCG AGAGGCAGCC 
GGCCCCGAGC CCCCTCCCGA GGCCCAGCCC TCACCACCCC CACCGCCTGG CTGCTGGGGC 
TGCTGGCAGA AGGGGCACGG GGAGGCCATG CCGCTGCACA GGTATGGGGT GGGTGAGGCG 
GCCGTAGGCG CTGAGGCCGG GGAGGCGACC CTCGGGGGTG GCGGTGGGGG CGGCTCCGTG 
GCTTCACCCA CCTCCAGCTC CGGCAGCTCC TCGAGGGGCA CTGAGAGGCC GCGCTCACTC 
AAGAGGGGCT CCAAGCCGTC GGCGTCCTCG GCCTCGCTGG AGAAGCGCAT GAAGATGGTG 
TCCCAGAGCT TCACCCAGCG CTTTCGGCTG TCTCGGGACA GGAAAGTGGC CAAGTCGCTG 
GCCGTCATCG TGAGCATCTT TGGGCTCTGC TGGGCCCCAT ACACGCTGCT GATGATCATC 
CGGGCCGCCT GCCATGGCCA CTGCGTCCCT GACTACTGGT ACGAAACCTC CTTCTGGCTC 
CTGTGGGCCA ACTCGGCTGT CAACCCTGTC CTCTACCCTC TGTGCCACCA CAGCTTCCGC 
CGGGCCTTCA CCAAGCTGCT CTGCCCCCAG AAGCTCAAAA TCCAGCCCCA CAGCTCCCTG 
GAGCACTGCT GGAAGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_009163.2
CDS	298..1635
Translation	MERAPPDGPLNASGALAGEAAAAGGARGFSAAWTAVLAALMALLIVATVLGNALVMLAFVADSSLRTQNNFFLLNLAISDFLVGAFCIPLYVPYVLTGRWTFGRGLCKLWLVVDYLLCTSSAFNIVLISYDRFLSVTRAVSYRAQQGDTRRAVRKMLLVWVLAFLLYGPAILSWEYLSGGSSIPEGHCYAEFFYNWYFLITASTLEFFTPFLSVTFFNLSIYLNIQRRTRLRLDGAREAAGPEPPPEAQPSPPPPPGCWGCWQKGHGEAMPLHRYGVGEAAVGAEAGEATLGGGGGGGSVASPTSSSGSSSRGTERPRSLKRGSKPSASSASLEKRMKMVSQSFTQRFRLSRDRKVAKSLAVIVSIFGLCWAPYTLLMIIRAACHGHCVPDYWYETSFWLLWANSAVNPVLYPLCHHSFRRAFTKLLCPQKLKIQPHSSLEHCWK

Target ORF information:

RefSeq Version	NM_007232.2
Organism	Homo sapiens(human)
Definition	Homo sapiens histamine receptor H3 (HRH3), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_007232.2

ORF Insert Sequence:

ATGGAGCGCG CGCCGCCCGA CGGGCCGCTG AACGCTTCGG GGGCGCTGGC GGGCGAGGCG 
GCGGCGGCGG GCGGGGCGCG CGGCTTCTCG GCAGCCTGGA CCGCGGTGCT GGCCGCGCTC 
ATGGCGCTGC TCATCGTGGC CACGGTGCTG GGCAACGCGC TGGTCATGCT CGCCTTCGTG 
GCCGACTCGA GCCTCCGCAC CCAGAACAAC TTCTTCCTGC TCAACCTCGC CATCTCCGAC 
TTCCTCGTCG GCGCCTTCTG CATCCCACTG TATGTACCCT ACGTGCTGAC AGGCCGCTGG 
ACCTTCGGCC GGGGCCTCTG CAAGCTGTGG CTGGTAGTGG ACTACCTGCT GTGCACCTCC 
TCTGCCTTCA ACATCGTGCT CATCAGCTAC GACCGCTTCC TGTCGGTCAC CCGAGCGGTC 
TCATACCGGG CCCAGCAGGG TGACACGCGG CGGGCAGTGC GGAAGATGCT GCTGGTGTGG 
GTGCTGGCCT TCCTGCTGTA CGGACCAGCC ATCCTGAGCT GGGAGTACCT GTCCGGGGGC 
AGCTCCATCC CCGAGGGCCA CTGCTATGCC GAGTTCTTCT ACAACTGGTA CTTCCTCATC 
ACGGCTTCCA CCCTGGAGTT CTTTACGCCC TTCCTCAGCG TCACCTTCTT TAACCTCAGC 
ATCTACCTGA ACATCCAGAG GCGCACCCGC CTCCGGCTGG ATGGGGCTCG AGAGGCAGCC 
GGCCCCGAGC CCCCTCCCGA GGCCCAGCCC TCACCACCCC CACCGCCTGG CTGCTGGGGC 
TGCTGGCAGA AGGGGCACGG GGAGGCCATG CCGCTGCACA GGTATGGGGT GGGTGAGGCG 
GCCGTAGGCG CTGAGGCCGG GGAGGCGACC CTCGGGGGTG GCGGTGGGGG CGGCTCCGTG 
GCTTCACCCA CCTCCAGCTC CGGCAGCTCC TCGAGGGGCA CTGAGAGGCC GCGCTCACTC 
AAGAGGGGCT CCAAGCCGTC GGCGTCCTCG GCCTCGCTGG AGAAGCGCAT GAAGATGGTG 
TCCCAGAGCT TCACCCAGCG CTTTCGGCTG TCTCGGGACA GGAAAGTGGC CAAGTCGCTG 
GCCGTCATCG TGAGCATCTT TGGGCTCTGC TGGGCCCCAT ACACGCTGCT GATGATCATC 
CGGGCCGCCT GCCATGGCCA CTGCGTCCCT GACTACTGGT ACGAAACCTC CTTCTGGCTC 
CTGTGGGCCA ACTCGGCTGT CAACCCTGTC CTCTACCCTC TGTGCCACCA CAGCTTCCGC 
CGGGCCTTCA CCAAGCTGCT CTGCCCCCAG AAGCTCAAAA TCCAGCCCCA CAGCTCCCTG 
GAGCACTGCT GGAAGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

HRH3 ( NM_007232.3 ) cDNA ORF clone, Homo sapiens(Human) -> NP_009163.2 Homo sapiens histamine receptor H3 (HRH3), mRNA.

Price & Availability↑

CloneID	OHu24367
Clone ID Related Accession (Same CDS sequence)	NM_007232.2 , NM_007232.3
Accession Version	NM_007232.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1338bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-29
Organism	Homo sapiens(human)
Product	histamine H3 receptor
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AL078633.32. On Nov 23, 2018 this sequence version replaced NM_007232.2. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AF140538.1, SRR3476690.923662.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2144335, SAMEA2145743 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000340177.10/ ENSP00000342560.5 RefSeq Select criteria :: based on conservation, expression ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGGAGCGCG CGCCGCCCGA CGGGCCGCTG AACGCTTCGG GGGCGCTGGC GGGCGAGGCG 
GCGGCGGCGG GCGGGGCGCG CGGCTTCTCG GCAGCCTGGA CCGCGGTGCT GGCCGCGCTC 
ATGGCGCTGC TCATCGTGGC CACGGTGCTG GGCAACGCGC TGGTCATGCT CGCCTTCGTG 
GCCGACTCGA GCCTCCGCAC CCAGAACAAC TTCTTCCTGC TCAACCTCGC CATCTCCGAC 
TTCCTCGTCG GCGCCTTCTG CATCCCACTG TATGTACCCT ACGTGCTGAC AGGCCGCTGG 
ACCTTCGGCC GGGGCCTCTG CAAGCTGTGG CTGGTAGTGG ACTACCTGCT GTGCACCTCC 
TCTGCCTTCA ACATCGTGCT CATCAGCTAC GACCGCTTCC TGTCGGTCAC CCGAGCGGTC 
TCATACCGGG CCCAGCAGGG TGACACGCGG CGGGCAGTGC GGAAGATGCT GCTGGTGTGG 
GTGCTGGCCT TCCTGCTGTA CGGACCAGCC ATCCTGAGCT GGGAGTACCT GTCCGGGGGC 
AGCTCCATCC CCGAGGGCCA CTGCTATGCC GAGTTCTTCT ACAACTGGTA CTTCCTCATC 
ACGGCTTCCA CCCTGGAGTT CTTTACGCCC TTCCTCAGCG TCACCTTCTT TAACCTCAGC 
ATCTACCTGA ACATCCAGAG GCGCACCCGC CTCCGGCTGG ATGGGGCTCG AGAGGCAGCC 
GGCCCCGAGC CCCCTCCCGA GGCCCAGCCC TCACCACCCC CACCGCCTGG CTGCTGGGGC 
TGCTGGCAGA AGGGGCACGG GGAGGCCATG CCGCTGCACA GGTATGGGGT GGGTGAGGCG 
GCCGTAGGCG CTGAGGCCGG GGAGGCGACC CTCGGGGGTG GCGGTGGGGG CGGCTCCGTG 
GCTTCACCCA CCTCCAGCTC CGGCAGCTCC TCGAGGGGCA CTGAGAGGCC GCGCTCACTC 
AAGAGGGGCT CCAAGCCGTC GGCGTCCTCG GCCTCGCTGG AGAAGCGCAT GAAGATGGTG 
TCCCAGAGCT TCACCCAGCG CTTTCGGCTG TCTCGGGACA GGAAAGTGGC CAAGTCGCTG 
GCCGTCATCG TGAGCATCTT TGGGCTCTGC TGGGCCCCAT ACACGCTGCT GATGATCATC 
CGGGCCGCCT GCCATGGCCA CTGCGTCCCT GACTACTGGT ACGAAACCTC CTTCTGGCTC 
CTGTGGGCCA ACTCGGCTGT CAACCCTGTC CTCTACCCTC TGTGCCACCA CAGCTTCCGC 
CGGGCCTTCA CCAAGCTGCT CTGCCCCCAG AAGCTCAAAA TCCAGCCCCA CAGCTCCCTG 
GAGCACTGCT GGAAGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_009163.2
CDS	309..1646
Translation	MERAPPDGPLNASGALAGEAAAAGGARGFSAAWTAVLAALMALLIVATVLGNALVMLAFVADSSLRTQNNFFLLNLAISDFLVGAFCIPLYVPYVLTGRWTFGRGLCKLWLVVDYLLCTSSAFNIVLISYDRFLSVTRAVSYRAQQGDTRRAVRKMLLVWVLAFLLYGPAILSWEYLSGGSSIPEGHCYAEFFYNWYFLITASTLEFFTPFLSVTFFNLSIYLNIQRRTRLRLDGAREAAGPEPPPEAQPSPPPPPGCWGCWQKGHGEAMPLHRYGVGEAAVGAEAGEATLGGGGGGGSVASPTSSSGSSSRGTERPRSLKRGSKPSASSASLEKRMKMVSQSFTQRFRLSRDRKVAKSLAVIVSIFGLCWAPYTLLMIIRAACHGHCVPDYWYETSFWLLWANSAVNPVLYPLCHHSFRRAFTKLLCPQKLKIQPHSSLEHCWK

Target ORF information:

RefSeq Version	NM_007232.3
Organism	Homo sapiens(human)
Definition	Homo sapiens histamine receptor H3 (HRH3), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_007232.3

ORF Insert Sequence:

ATGGAGCGCG CGCCGCCCGA CGGGCCGCTG AACGCTTCGG GGGCGCTGGC GGGCGAGGCG 
GCGGCGGCGG GCGGGGCGCG CGGCTTCTCG GCAGCCTGGA CCGCGGTGCT GGCCGCGCTC 
ATGGCGCTGC TCATCGTGGC CACGGTGCTG GGCAACGCGC TGGTCATGCT CGCCTTCGTG 
GCCGACTCGA GCCTCCGCAC CCAGAACAAC TTCTTCCTGC TCAACCTCGC CATCTCCGAC 
TTCCTCGTCG GCGCCTTCTG CATCCCACTG TATGTACCCT ACGTGCTGAC AGGCCGCTGG 
ACCTTCGGCC GGGGCCTCTG CAAGCTGTGG CTGGTAGTGG ACTACCTGCT GTGCACCTCC 
TCTGCCTTCA ACATCGTGCT CATCAGCTAC GACCGCTTCC TGTCGGTCAC CCGAGCGGTC 
TCATACCGGG CCCAGCAGGG TGACACGCGG CGGGCAGTGC GGAAGATGCT GCTGGTGTGG 
GTGCTGGCCT TCCTGCTGTA CGGACCAGCC ATCCTGAGCT GGGAGTACCT GTCCGGGGGC 
AGCTCCATCC CCGAGGGCCA CTGCTATGCC GAGTTCTTCT ACAACTGGTA CTTCCTCATC 
ACGGCTTCCA CCCTGGAGTT CTTTACGCCC TTCCTCAGCG TCACCTTCTT TAACCTCAGC 
ATCTACCTGA ACATCCAGAG GCGCACCCGC CTCCGGCTGG ATGGGGCTCG AGAGGCAGCC 
GGCCCCGAGC CCCCTCCCGA GGCCCAGCCC TCACCACCCC CACCGCCTGG CTGCTGGGGC 
TGCTGGCAGA AGGGGCACGG GGAGGCCATG CCGCTGCACA GGTATGGGGT GGGTGAGGCG 
GCCGTAGGCG CTGAGGCCGG GGAGGCGACC CTCGGGGGTG GCGGTGGGGG CGGCTCCGTG 
GCTTCACCCA CCTCCAGCTC CGGCAGCTCC TCGAGGGGCA CTGAGAGGCC GCGCTCACTC 
AAGAGGGGCT CCAAGCCGTC GGCGTCCTCG GCCTCGCTGG AGAAGCGCAT GAAGATGGTG 
TCCCAGAGCT TCACCCAGCG CTTTCGGCTG TCTCGGGACA GGAAAGTGGC CAAGTCGCTG 
GCCGTCATCG TGAGCATCTT TGGGCTCTGC TGGGCCCCAT ACACGCTGCT GATGATCATC 
CGGGCCGCCT GCCATGGCCA CTGCGTCCCT GACTACTGGT ACGAAACCTC CTTCTGGCTC 
CTGTGGGCCA ACTCGGCTGT CAACCCTGTC CTCTACCCTC TGTGCCACCA CAGCTTCCGC 
CGGGCCTTCA CCAAGCTGCT CTGCCCCCAG AAGCTCAAAA TCCAGCCCCA CAGCTCCCTG 
GAGCACTGCT GGAAGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

HRH3 ( XM_017027623.1 ) cDNA ORF clone, Homo sapiens(Human) -> XP_016883112.1 Homo sapiens histamine receptor H3 (HRH3), transcript variant X2, mRNA.

Price & Availability↑

CloneID	OHu92899
Clone ID Related Accession (Same CDS sequence)	XM_017027623.1
Accession Version	XM_017027623.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1200bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	histamine H3 receptor isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000020.11) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGCGCTGC TCATCGTGGC CACGGTGCTG GGCAACGCGC TGGTCATGCT CGCCTTCGTG 
GCCGACTCGA GCCTCCGCAC CCAGAACAAC TTCTTCCTGC TCAACCTCGC CATCTCCGAC 
TTCCTCGTCG GCCGCTGGAC CTTCGGCCGG GGCCTCTGCA AGCTGTGGCT GGTAGTGGAC 
TACCTGCTGT GCACCTCCTC TGCCTTCAAC ATCGTGCTCA TCAGCTACGA CCGCTTCCTG 
TCGGTCACCC GAGCGGTCTC ATACCGGGCC CAGCAGGGTG ACACGCGGCG GGCAGTGCGG 
AAGATGCTGC TGGTGTGGGT GCTGGCCTTC CTGCTGTACG GACCAGCCAT CCTGAGCTGG 
GAGTACCTGT CCGGGGGCAG CTCCATCCCC GAGGGCCACT GCTATGCCGA GTTCTTCTAC 
AACTGGTACT TCCTCATCAC GGCTTCCACC CTGGAGTTCT TTACGCCCTT CCTCAGCGTC 
ACCTTCTTTA ACCTCAGCAT CTACCTGAAC ATCCAGAGGC GCACCCGCCT CCGGCTGGAT 
GGGGCTCGAG AGGCAGCCGG CCCCGAGCCC CCTCCCGAGG CCCAGCCCTC ACCACCCCCA 
CCGCCTGGCT GCTGGGGCTG CTGGCAGAAG GGGCACGGGG AGGCCATGCC GCTGCACAGG 
TATGGGGTGG GTGAGGCGGC CGTAGGCGCT GAGGCCGGGG AGGCGACCCT CGGGGGTGGC 
GGTGGGGGCG GCTCCGTGGC TTCACCCACC TCCAGCTCCG GCAGCTCCTC GAGGGGCACT 
GAGAGGCCGC GCTCACTCAA GAGGGGCTCC AAGCCGTCGG CGTCCTCGGC CTCGCTGGAG 
AAGCGCATGA AGATGGTGTC CCAGAGCTTC ACCCAGCGCT TTCGGCTGTC TCGGGACAGG 
AAAGTGGCCA AGTCGCTGGC CGTCATCGTG AGCATCTTTG GGCTCTGCTG GGCCCCATAC 
ACGCTGCTGA TGATCATCCG GGCCGCCTGC CATGGCCACT GCGTCCCTGA CTACTGGTAC 
GAAACCTCCT TCTGGCTCCT GTGGGCCAAC TCGGCTGTCA ACCCTGTCCT CTACCCTCTG 
TGCCACCACA GCTTCCGCCG GGCCTTCACC AAGCTGCTCT GCCCCCAGAA GCTCAAAATC 
CAGCCCCACA GCTCCCTGGA GCACTGCTGG AAAAAGATGA AGAAGAAAAC ATGTCTGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_016883112.1
CDS	39..1238
Translation	MALLIVATVLGNALVMLAFVADSSLRTQNNFFLLNLAISDFLVGRWTFGRGLCKLWLVVDYLLCTSSAFNIVLISYDRFLSVTRAVSYRAQQGDTRRAVRKMLLVWVLAFLLYGPAILSWEYLSGGSSIPEGHCYAEFFYNWYFLITASTLEFFTPFLSVTFFNLSIYLNIQRRTRLRLDGAREAAGPEPPPEAQPSPPPPPGCWGCWQKGHGEAMPLHRYGVGEAAVGAEAGEATLGGGGGGGSVASPTSSSGSSSRGTERPRSLKRGSKPSASSASLEKRMKMVSQSFTQRFRLSRDRKVAKSLAVIVSIFGLCWAPYTLLMIIRAACHGHCVPDYWYETSFWLLWANSAVNPVLYPLCHHSFRRAFTKLLCPQKLKIQPHSSLEHCWKKMKKKTCL

Target ORF information:

RefSeq Version	XM_017027623.1
Organism	Homo sapiens(human)
Definition	Homo sapiens histamine receptor H3 (HRH3), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017027623.1

ORF Insert Sequence:

ATGGCGCTGC TCATCGTGGC CACGGTGCTG GGCAACGCGC TGGTCATGCT CGCCTTCGTG 
GCCGACTCGA GCCTCCGCAC CCAGAACAAC TTCTTCCTGC TCAACCTCGC CATCTCCGAC 
TTCCTCGTCG GCCGCTGGAC CTTCGGCCGG GGCCTCTGCA AGCTGTGGCT GGTAGTGGAC 
TACCTGCTGT GCACCTCCTC TGCCTTCAAC ATCGTGCTCA TCAGCTACGA CCGCTTCCTG 
TCGGTCACCC GAGCGGTCTC ATACCGGGCC CAGCAGGGTG ACACGCGGCG GGCAGTGCGG 
AAGATGCTGC TGGTGTGGGT GCTGGCCTTC CTGCTGTACG GACCAGCCAT CCTGAGCTGG 
GAGTACCTGT CCGGGGGCAG CTCCATCCCC GAGGGCCACT GCTATGCCGA GTTCTTCTAC 
AACTGGTACT TCCTCATCAC GGCTTCCACC CTGGAGTTCT TTACGCCCTT CCTCAGCGTC 
ACCTTCTTTA ACCTCAGCAT CTACCTGAAC ATCCAGAGGC GCACCCGCCT CCGGCTGGAT 
GGGGCTCGAG AGGCAGCCGG CCCCGAGCCC CCTCCCGAGG CCCAGCCCTC ACCACCCCCA 
CCGCCTGGCT GCTGGGGCTG CTGGCAGAAG GGGCACGGGG AGGCCATGCC GCTGCACAGG 
TATGGGGTGG GTGAGGCGGC CGTAGGCGCT GAGGCCGGGG AGGCGACCCT CGGGGGTGGC 
GGTGGGGGCG GCTCCGTGGC TTCACCCACC TCCAGCTCCG GCAGCTCCTC GAGGGGCACT 
GAGAGGCCGC GCTCACTCAA GAGGGGCTCC AAGCCGTCGG CGTCCTCGGC CTCGCTGGAG 
AAGCGCATGA AGATGGTGTC CCAGAGCTTC ACCCAGCGCT TTCGGCTGTC TCGGGACAGG 
AAAGTGGCCA AGTCGCTGGC CGTCATCGTG AGCATCTTTG GGCTCTGCTG GGCCCCATAC 
ACGCTGCTGA TGATCATCCG GGCCGCCTGC CATGGCCACT GCGTCCCTGA CTACTGGTAC 
GAAACCTCCT TCTGGCTCCT GTGGGCCAAC TCGGCTGTCA ACCCTGTCCT CTACCCTCTG 
TGCCACCACA GCTTCCGCCG GGCCTTCACC AAGCTGCTCT GCCCCCAGAA GCTCAAAATC 
CAGCCCCACA GCTCCCTGGA GCACTGCTGG AAAAAGATGA AGAAGAAAAC ATGTCTGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

HRH3 ( XM_005260266.3 ) cDNA ORF clone, Homo sapiens(Human) -> XP_005260323.1 Homo sapiens histamine receptor H3 (HRH3), transcript variant X1, mRNA.

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CloneID	OHu52880
Clone ID Related Accession (Same CDS sequence)	XM_005260266.3 , XM_005260266.2
Accession Version	XM_005260266.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1362bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	histamine H3 receptor isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000020.11) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 6, 2016 this sequence version replaced XM_005260266.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGAGCGCG CGCCGCCCGA CGGGCCGCTG AACGCTTCGG GGGCGCTGGC GGGCGAGGCG 
GCGGCGGCGG GCGGGGCGCG CGGCTTCTCG GCAGCCTGGA CCGCGGTGCT GGCCGCGCTC 
ATGGCGCTGC TCATCGTGGC CACGGTGCTG GGCAACGCGC TGGTCATGCT CGCCTTCGTG 
GCCGACTCGA GCCTCCGCAC CCAGAACAAC TTCTTCCTGC TCAACCTCGC CATCTCCGAC 
TTCCTCGTCG GCGCCTTCTG CATCCCACTG TATGTACCCT ACGTGCTGAC AGGCCGCTGG 
ACCTTCGGCC GGGGCCTCTG CAAGCTGTGG CTGGTAGTGG ACTACCTGCT GTGCACCTCC 
TCTGCCTTCA ACATCGTGCT CATCAGCTAC GACCGCTTCC TGTCGGTCAC CCGAGCGGTC 
TCATACCGGG CCCAGCAGGG TGACACGCGG CGGGCAGTGC GGAAGATGCT GCTGGTGTGG 
GTGCTGGCCT TCCTGCTGTA CGGACCAGCC ATCCTGAGCT GGGAGTACCT GTCCGGGGGC 
AGCTCCATCC CCGAGGGCCA CTGCTATGCC GAGTTCTTCT ACAACTGGTA CTTCCTCATC 
ACGGCTTCCA CCCTGGAGTT CTTTACGCCC TTCCTCAGCG TCACCTTCTT TAACCTCAGC 
ATCTACCTGA ACATCCAGAG GCGCACCCGC CTCCGGCTGG ATGGGGCTCG AGAGGCAGCC 
GGCCCCGAGC CCCCTCCCGA GGCCCAGCCC TCACCACCCC CACCGCCTGG CTGCTGGGGC 
TGCTGGCAGA AGGGGCACGG GGAGGCCATG CCGCTGCACA GGTATGGGGT GGGTGAGGCG 
GCCGTAGGCG CTGAGGCCGG GGAGGCGACC CTCGGGGGTG GCGGTGGGGG CGGCTCCGTG 
GCTTCACCCA CCTCCAGCTC CGGCAGCTCC TCGAGGGGCA CTGAGAGGCC GCGCTCACTC 
AAGAGGGGCT CCAAGCCGTC GGCGTCCTCG GCCTCGCTGG AGAAGCGCAT GAAGATGGTG 
TCCCAGAGCT TCACCCAGCG CTTTCGGCTG TCTCGGGACA GGAAAGTGGC CAAGTCGCTG 
GCCGTCATCG TGAGCATCTT TGGGCTCTGC TGGGCCCCAT ACACGCTGCT GATGATCATC 
CGGGCCGCCT GCCATGGCCA CTGCGTCCCT GACTACTGGT ACGAAACCTC CTTCTGGCTC 
CTGTGGGCCA ACTCGGCTGT CAACCCTGTC CTCTACCCTC TGTGCCACCA CAGCTTCCGC 
CGGGCCTTCA CCAAGCTGCT CTGCCCCCAG AAGCTCAAAA TCCAGCCCCA CAGCTCCCTG 
GAGCACTGCT GGAAAAAGAT GAAGAAGAAA ACATGTCTGT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_005260323.1
CDS	1..1362
Translation	MERAPPDGPLNASGALAGEAAAAGGARGFSAAWTAVLAALMALLIVATVLGNALVMLAFVADSSLRTQNNFFLLNLAISDFLVGAFCIPLYVPYVLTGRWTFGRGLCKLWLVVDYLLCTSSAFNIVLISYDRFLSVTRAVSYRAQQGDTRRAVRKMLLVWVLAFLLYGPAILSWEYLSGGSSIPEGHCYAEFFYNWYFLITASTLEFFTPFLSVTFFNLSIYLNIQRRTRLRLDGAREAAGPEPPPEAQPSPPPPPGCWGCWQKGHGEAMPLHRYGVGEAAVGAEAGEATLGGGGGGGSVASPTSSSGSSSRGTERPRSLKRGSKPSASSASLEKRMKMVSQSFTQRFRLSRDRKVAKSLAVIVSIFGLCWAPYTLLMIIRAACHGHCVPDYWYETSFWLLWANSAVNPVLYPLCHHSFRRAFTKLLCPQKLKIQPHSSLEHCWKKMKKKTCL

Target ORF information:

RefSeq Version	XM_005260266.3
Organism	Homo sapiens(human)
Definition	Homo sapiens histamine receptor H3 (HRH3), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_005260266.3

ORF Insert Sequence:

ATGGAGCGCG CGCCGCCCGA CGGGCCGCTG AACGCTTCGG GGGCGCTGGC GGGCGAGGCG 
GCGGCGGCGG GCGGGGCGCG CGGCTTCTCG GCAGCCTGGA CCGCGGTGCT GGCCGCGCTC 
ATGGCGCTGC TCATCGTGGC CACGGTGCTG GGCAACGCGC TGGTCATGCT CGCCTTCGTG 
GCCGACTCGA GCCTCCGCAC CCAGAACAAC TTCTTCCTGC TCAACCTCGC CATCTCCGAC 
TTCCTCGTCG GCGCCTTCTG CATCCCACTG TATGTACCCT ACGTGCTGAC AGGCCGCTGG 
ACCTTCGGCC GGGGCCTCTG CAAGCTGTGG CTGGTAGTGG ACTACCTGCT GTGCACCTCC 
TCTGCCTTCA ACATCGTGCT CATCAGCTAC GACCGCTTCC TGTCGGTCAC CCGAGCGGTC 
TCATACCGGG CCCAGCAGGG TGACACGCGG CGGGCAGTGC GGAAGATGCT GCTGGTGTGG 
GTGCTGGCCT TCCTGCTGTA CGGACCAGCC ATCCTGAGCT GGGAGTACCT GTCCGGGGGC 
AGCTCCATCC CCGAGGGCCA CTGCTATGCC GAGTTCTTCT ACAACTGGTA CTTCCTCATC 
ACGGCTTCCA CCCTGGAGTT CTTTACGCCC TTCCTCAGCG TCACCTTCTT TAACCTCAGC 
ATCTACCTGA ACATCCAGAG GCGCACCCGC CTCCGGCTGG ATGGGGCTCG AGAGGCAGCC 
GGCCCCGAGC CCCCTCCCGA GGCCCAGCCC TCACCACCCC CACCGCCTGG CTGCTGGGGC 
TGCTGGCAGA AGGGGCACGG GGAGGCCATG CCGCTGCACA GGTATGGGGT GGGTGAGGCG 
GCCGTAGGCG CTGAGGCCGG GGAGGCGACC CTCGGGGGTG GCGGTGGGGG CGGCTCCGTG 
GCTTCACCCA CCTCCAGCTC CGGCAGCTCC TCGAGGGGCA CTGAGAGGCC GCGCTCACTC 
AAGAGGGGCT CCAAGCCGTC GGCGTCCTCG GCCTCGCTGG AGAAGCGCAT GAAGATGGTG 
TCCCAGAGCT TCACCCAGCG CTTTCGGCTG TCTCGGGACA GGAAAGTGGC CAAGTCGCTG 
GCCGTCATCG TGAGCATCTT TGGGCTCTGC TGGGCCCCAT ACACGCTGCT GATGATCATC 
CGGGCCGCCT GCCATGGCCA CTGCGTCCCT GACTACTGGT ACGAAACCTC CTTCTGGCTC 
CTGTGGGCCA ACTCGGCTGT CAACCCTGTC CTCTACCCTC TGTGCCACCA CAGCTTCCGC 
CGGGCCTTCA CCAAGCTGCT CTGCCCCCAG AAGCTCAAAA TCCAGCCCCA CAGCTCCCTG 
GAGCACTGCT GGAAAAAGAT GAAGAAGAAA ACATGTCTGT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

HRH3 ( XM_005260266.2 ) cDNA ORF clone, Homo sapiens(Human) -> XP_005260323.1 Homo sapiens histamine receptor H3 (HRH3), transcript variant X1, mRNA.

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CloneID	OHu52880
Clone ID Related Accession (Same CDS sequence)	XM_005260266.3 , XM_005260266.2
Accession Version	XM_005260266.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1362bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2015-03-11
Organism	Homo sapiens(Human)
Product	histamine H3 receptor isoform X1
Comment

ATGGAGCGCG CGCCGCCCGA CGGGCCGCTG AACGCTTCGG GGGCGCTGGC GGGCGAGGCG 
GCGGCGGCGG GCGGGGCGCG CGGCTTCTCG GCAGCCTGGA CCGCGGTGCT GGCCGCGCTC 
ATGGCGCTGC TCATCGTGGC CACGGTGCTG GGCAACGCGC TGGTCATGCT CGCCTTCGTG 
GCCGACTCGA GCCTCCGCAC CCAGAACAAC TTCTTCCTGC TCAACCTCGC CATCTCCGAC 
TTCCTCGTCG GCGCCTTCTG CATCCCACTG TATGTACCCT ACGTGCTGAC AGGCCGCTGG 
ACCTTCGGCC GGGGCCTCTG CAAGCTGTGG CTGGTAGTGG ACTACCTGCT GTGCACCTCC 
TCTGCCTTCA ACATCGTGCT CATCAGCTAC GACCGCTTCC TGTCGGTCAC CCGAGCGGTC 
TCATACCGGG CCCAGCAGGG TGACACGCGG CGGGCAGTGC GGAAGATGCT GCTGGTGTGG 
GTGCTGGCCT TCCTGCTGTA CGGACCAGCC ATCCTGAGCT GGGAGTACCT GTCCGGGGGC 
AGCTCCATCC CCGAGGGCCA CTGCTATGCC GAGTTCTTCT ACAACTGGTA CTTCCTCATC 
ACGGCTTCCA CCCTGGAGTT CTTTACGCCC TTCCTCAGCG TCACCTTCTT TAACCTCAGC 
ATCTACCTGA ACATCCAGAG GCGCACCCGC CTCCGGCTGG ATGGGGCTCG AGAGGCAGCC 
GGCCCCGAGC CCCCTCCCGA GGCCCAGCCC TCACCACCCC CACCGCCTGG CTGCTGGGGC 
TGCTGGCAGA AGGGGCACGG GGAGGCCATG CCGCTGCACA GGTATGGGGT GGGTGAGGCG 
GCCGTAGGCG CTGAGGCCGG GGAGGCGACC CTCGGGGGTG GCGGTGGGGG CGGCTCCGTG 
GCTTCACCCA CCTCCAGCTC CGGCAGCTCC TCGAGGGGCA CTGAGAGGCC GCGCTCACTC 
AAGAGGGGCT CCAAGCCGTC GGCGTCCTCG GCCTCGCTGG AGAAGCGCAT GAAGATGGTG 
TCCCAGAGCT TCACCCAGCG CTTTCGGCTG TCTCGGGACA GGAAAGTGGC CAAGTCGCTG 
GCCGTCATCG TGAGCATCTT TGGGCTCTGC TGGGCCCCAT ACACGCTGCT GATGATCATC 
CGGGCCGCCT GCCATGGCCA CTGCGTCCCT GACTACTGGT ACGAAACCTC CTTCTGGCTC 
CTGTGGGCCA ACTCGGCTGT CAACCCTGTC CTCTACCCTC TGTGCCACCA CAGCTTCCGC 
CGGGCCTTCA CCAAGCTGCT CTGCCCCCAG AAGCTCAAAA TCCAGCCCCA CAGCTCCCTG 
GAGCACTGCT GGAAAAAGAT GAAGAAGAAA ACATGTCTGT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq

XP_005260323.1

Translation

MERAPPDGPLNASGALAGEAAAAGGARGFSAAWTAVLAALMALLIVATVLGNALVMLAFVADSSLRTQNNFFLLNLAISDFLVGAFCIPLYVPYVLTGRWTFGRGLCKLWLVVDYLLCTSSAFNIVLISYDRFLSVTRAVSYRAQQGDTRRAVRKMLLVWVLAFLLYGPAILSWEYLSGGSSIPEGHCYAEFFYNWYFLITASTLEFFTPFLSVTFFNLSIYLNIQRRTRLRLDGAREAAGPEPPPEAQPSPPPPPGCWGCWQKGHGEAMPLHRYGVGEAAVGAEAGEATLGGGGGGGSVASPTSSSGSSSRGTERPRSLKRGSKPSASSASLEKRMKMVSQSFTQRFRLSRDRKVAKSLAVIVSIFGLCWAPYTLLMIIRAACHGHCVPDYWYETSFWLLWANSAVNPVLYPLCHHSFRRAFTKLLCPQKLKIQPHSSLEHCWKKMKKKTCL

Target ORF information:

RefSeq Version	XM_005260266.2
Organism	Homo sapiens(Human)
Definition	Homo sapiens histamine receptor H3 (HRH3), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_005260266.2

ORF Insert Sequence:

ATGGAGCGCG CGCCGCCCGA CGGGCCGCTG AACGCTTCGG GGGCGCTGGC GGGCGAGGCG 
GCGGCGGCGG GCGGGGCGCG CGGCTTCTCG GCAGCCTGGA CCGCGGTGCT GGCCGCGCTC 
ATGGCGCTGC TCATCGTGGC CACGGTGCTG GGCAACGCGC TGGTCATGCT CGCCTTCGTG 
GCCGACTCGA GCCTCCGCAC CCAGAACAAC TTCTTCCTGC TCAACCTCGC CATCTCCGAC 
TTCCTCGTCG GCGCCTTCTG CATCCCACTG TATGTACCCT ACGTGCTGAC AGGCCGCTGG 
ACCTTCGGCC GGGGCCTCTG CAAGCTGTGG CTGGTAGTGG ACTACCTGCT GTGCACCTCC 
TCTGCCTTCA ACATCGTGCT CATCAGCTAC GACCGCTTCC TGTCGGTCAC CCGAGCGGTC 
TCATACCGGG CCCAGCAGGG TGACACGCGG CGGGCAGTGC GGAAGATGCT GCTGGTGTGG 
GTGCTGGCCT TCCTGCTGTA CGGACCAGCC ATCCTGAGCT GGGAGTACCT GTCCGGGGGC 
AGCTCCATCC CCGAGGGCCA CTGCTATGCC GAGTTCTTCT ACAACTGGTA CTTCCTCATC 
ACGGCTTCCA CCCTGGAGTT CTTTACGCCC TTCCTCAGCG TCACCTTCTT TAACCTCAGC 
ATCTACCTGA ACATCCAGAG GCGCACCCGC CTCCGGCTGG ATGGGGCTCG AGAGGCAGCC 
GGCCCCGAGC CCCCTCCCGA GGCCCAGCCC TCACCACCCC CACCGCCTGG CTGCTGGGGC 
TGCTGGCAGA AGGGGCACGG GGAGGCCATG CCGCTGCACA GGTATGGGGT GGGTGAGGCG 
GCCGTAGGCG CTGAGGCCGG GGAGGCGACC CTCGGGGGTG GCGGTGGGGG CGGCTCCGTG 
GCTTCACCCA CCTCCAGCTC CGGCAGCTCC TCGAGGGGCA CTGAGAGGCC GCGCTCACTC 
AAGAGGGGCT CCAAGCCGTC GGCGTCCTCG GCCTCGCTGG AGAAGCGCAT GAAGATGGTG 
TCCCAGAGCT TCACCCAGCG CTTTCGGCTG TCTCGGGACA GGAAAGTGGC CAAGTCGCTG 
GCCGTCATCG TGAGCATCTT TGGGCTCTGC TGGGCCCCAT ACACGCTGCT GATGATCATC 
CGGGCCGCCT GCCATGGCCA CTGCGTCCCT GACTACTGGT ACGAAACCTC CTTCTGGCTC 
CTGTGGGCCA ACTCGGCTGT CAACCCTGTC CTCTACCCTC TGTGCCACCA CAGCTTCCGC 
CGGGCCTTCA CCAAGCTGCT CTGCCCCCAG AAGCTCAAAA TCCAGCCCCA CAGCTCCCTG 
GAGCACTGCT GGAAAAAGAT GAAGAAGAAA ACATGTCTGT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

HRH3 ( XM_005260267.3 ) cDNA ORF clone, Homo sapiens(Human) -> XP_005260324.1 Homo sapiens histamine receptor H3 (HRH3), transcript variant X2, mRNA.

Price & Availability↑

CloneID	OHu52882
Clone ID Related Accession (Same CDS sequence)	XM_005260267.3
Accession Version	XM_005260267.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1122bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2015-03-11
Organism	Homo sapiens(Human)
Product	histamine H3 receptor isoform X2
Comment

ATGGAGCGCG CGCCGCCCGA CGGGCCGCTG AACGCTTCGG GGGCGCTGGC GGGCGAGGCG 
GCGGCGGCGG GCGGGGCGCG CGGCTTCTCG GCAGCCTGGA CCGCGGTGCT GGCCGCGCTC 
ATGGCGCTGC TCATCGTGGC CACGGTGCTG GGCAACGCGC TGGTCATGCT CGCCTTCGTG 
GCCGACTCGA GCCTCCGCAC CCAGAACAAC TTCTTCCTGC TCAACCTCGC CATCTCCGAC 
TTCCTCGTCG GCGCCTTCTG CATCCCACTG TATGTACCCT ACGTGCTGAC AGGCCGCTGG 
ACCTTCGGCC GGGGCCTCTG CAAGCTGTGG CTGGTAGTGG ACTACCTGCT GTGCACCTCC 
TCTGCCTTCA ACATCGTGCT CATCAGCTAC GACCGCTTCC TGTCGGTCAC CCGAGCGGTC 
TCATACCGGG CCCAGCAGGG TGACACGCGG CGGGCAGTGC GGAAGATGCT GCTGGTGTGG 
GTGCTGGCCT TCCTGCTGTA CGGACCAGCC ATCCTGAGCT GGGAGTACCT GTCCGGGGGC 
AGCTCCATCC CCGAGGGCCA CTGCTATGCC GAGTTCTTCT ACAACTGGTA CTTCCTCATC 
ACGGCTTCCA CCCTGGAGTT CTTTACGCCC TTCCTCAGCG TCACCTTCTT TAACCTCAGC 
ATCTACCTGA ACATCCAGAG GCGCACCCGC CTCCGGCTGG ATGGGGCTCG AGAGGCAGCC 
GGCCCCGAGC CCCCTCCCGA GGCCCAGCCC TCACCACCCC CACCGCCTGG CTGCTGGGGC 
TGCTGGCAGA AGGGGCACGG GGAGGCCATG CCGCTGCACA GGAAAGTGGC CAAGTCGCTG 
GCCGTCATCG TGAGCATCTT TGGGCTCTGC TGGGCCCCAT ACACGCTGCT GATGATCATC 
CGGGCCGCCT GCCATGGCCA CTGCGTCCCT GACTACTGGT ACGAAACCTC CTTCTGGCTC 
CTGTGGGCCA ACTCGGCTGT CAACCCTGTC CTCTACCCTC TGTGCCACCA CAGCTTCCGC 
CGGGCCTTCA CCAAGCTGCT CTGCCCCCAG AAGCTCAAAA TCCAGCCCCA CAGCTCCCTG 
GAGCACTGCT GGAAAAAGAT GAAGAAGAAA ACATGTCTGT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_005260324.1
Translation	MERAPPDGPLNASGALAGEAAAAGGARGFSAAWTAVLAALMALLIVATVLGNALVMLAFVADSSLRTQNNFFLLNLAISDFLVGAFCIPLYVPYVLTGRWTFGRGLCKLWLVVDYLLCTSSAFNIVLISYDRFLSVTRAVSYRAQQGDTRRAVRKMLLVWVLAFLLYGPAILSWEYLSGGSSIPEGHCYAEFFYNWYFLITASTLEFFTPFLSVTFFNLSIYLNIQRRTRLRLDGAREAAGPEPPPEAQPSPPPPPGCWGCWQKGHGEAMPLHRKVAKSLAVIVSIFGLCWAPYTLLMIIRAACHGHCVPDYWYETSFWLLWANSAVNPVLYPLCHHSFRRAFTKLLCPQKLKIQPHSSLEHCWKKMKKKTCL

Target ORF information:

RefSeq Version	XM_005260267.3
Organism	Homo sapiens(Human)
Definition	Homo sapiens histamine receptor H3 (HRH3), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_005260267.3

ORF Insert Sequence:

ATGGAGCGCG CGCCGCCCGA CGGGCCGCTG AACGCTTCGG GGGCGCTGGC GGGCGAGGCG 
GCGGCGGCGG GCGGGGCGCG CGGCTTCTCG GCAGCCTGGA CCGCGGTGCT GGCCGCGCTC 
ATGGCGCTGC TCATCGTGGC CACGGTGCTG GGCAACGCGC TGGTCATGCT CGCCTTCGTG 
GCCGACTCGA GCCTCCGCAC CCAGAACAAC TTCTTCCTGC TCAACCTCGC CATCTCCGAC 
TTCCTCGTCG GCGCCTTCTG CATCCCACTG TATGTACCCT ACGTGCTGAC AGGCCGCTGG 
ACCTTCGGCC GGGGCCTCTG CAAGCTGTGG CTGGTAGTGG ACTACCTGCT GTGCACCTCC 
TCTGCCTTCA ACATCGTGCT CATCAGCTAC GACCGCTTCC TGTCGGTCAC CCGAGCGGTC 
TCATACCGGG CCCAGCAGGG TGACACGCGG CGGGCAGTGC GGAAGATGCT GCTGGTGTGG 
GTGCTGGCCT TCCTGCTGTA CGGACCAGCC ATCCTGAGCT GGGAGTACCT GTCCGGGGGC 
AGCTCCATCC CCGAGGGCCA CTGCTATGCC GAGTTCTTCT ACAACTGGTA CTTCCTCATC 
ACGGCTTCCA CCCTGGAGTT CTTTACGCCC TTCCTCAGCG TCACCTTCTT TAACCTCAGC 
ATCTACCTGA ACATCCAGAG GCGCACCCGC CTCCGGCTGG ATGGGGCTCG AGAGGCAGCC 
GGCCCCGAGC CCCCTCCCGA GGCCCAGCCC TCACCACCCC CACCGCCTGG CTGCTGGGGC 
TGCTGGCAGA AGGGGCACGG GGAGGCCATG CCGCTGCACA GGAAAGTGGC CAAGTCGCTG 
GCCGTCATCG TGAGCATCTT TGGGCTCTGC TGGGCCCCAT ACACGCTGCT GATGATCATC 
CGGGCCGCCT GCCATGGCCA CTGCGTCCCT GACTACTGGT ACGAAACCTC CTTCTGGCTC 
CTGTGGGCCA ACTCGGCTGT CAACCCTGTC CTCTACCCTC TGTGCCACCA CAGCTTCCGC 
CGGGCCTTCA CCAAGCTGCT CTGCCCCCAG AAGCTCAAAA TCCAGCCCCA CAGCTCCCTG 
GAGCACTGCT GGAAAAAGAT GAAGAAGAAA ACATGTCTGT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

The naturally occurring mutation Y197C does not affect the expression or signaling of the human histamine H
Neuroscience letters64177-80(2017 Feb)
Flores-Clemente C,Escamilla-S?nchez J,Arias JM,Arias-Monta?o JA

Histamine Receptor 3 negatively regulates oligodendrocyte differentiation and remyelination.
PloS one12(12)e0189380(2017)
Chen Y,Zhen W,Guo T,Zhao Y,Liu A,Rubio JP,Krull D,Richardson JC,Lu H,Wang R

Associations of Polymorphisms in HRH2, HRH3, DAO, and HNMT Genes with Risk of Chronic Heart Failure.
BioMed research international20161208476(2016)
He GH,Cai WK,Zhang JB,Ma CY,Yan F,Lu J,Xu GL

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HRH3 cDNA ORF clone, Homo sapiens(Human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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