Gene Symbol | PTGDR2 |
Entrez Gene ID | 11251 |
Full Name | prostaglandin D2 receptor 2 |
Synonyms | CD294,CRTH2,DL1R,DP2,GPR44 |
General protein information |
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Gene Type | protein-coding |
Organism | Homo sapiens(human) |
Genome | |
Summary | This gene encodes a G-protein-coupled receptor that is preferentially expressed in CD4+ effector T helper 2 (Th2) cells. This protein is a prostaglandin D2 receptor that mediates the pro-inflammatory chemotaxis of eosinophils, basophils, and Th2 lymphocytes generated during allergic inflammation. Single nucleotide polymorphisms in the 3' UTR of this gene have been associated with asthma susceptibility.[provided by RefSeq, Mar 2011]. |
Disorder MIM: |