ADAMTS8 cDNA ORF clone, Homo sapiens(Human)

Gene
Clones
gRNAs

Summary

Gene Symbol	ADAMTS8
Entrez Gene ID	11095
Full Name	ADAM metallopeptidase with thrombospondin type 1 motif 8
Synonyms	ADAM-TS8,METH2
General protein information	Preferred Names ADAM metallopeptidase with thrombospondin type 1 motif 8 Names A disintegrin and metalloproteinase with thrombospondin motifs 8 ADAMTS-8 METH-2 METH-8 a disintegrin-like and metalloprotease (reprolysin type) with thrombospondin type 1 motif, 8
Gene Type	protein-coding
Organism	Homo sapiens(Human)
Genome	Chromosome: 11 Map Location: 11q24.3
Summary	This gene encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) protein family. Members of the family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. The encoded preproprotein is proteolytically processed to generate the mature enzyme. This enzyme contains two C-terminal TS motifs, and disrupts angiogenesis in vivo. A number of disorders have been mapped in the vicinity of this gene, most notably lung neoplasms. Reduced expression of this gene has been observed in multiple human cancers and this gene has been proposed as a potential tumor suppressor. [provided by RefSeq, Feb 2016].
Disorder MIM:	605175

mRNA and Protein(s)

mRNA	Protein	Name
XM_017017145.1	XP_016872634.1	A disintegrin and metalloproteinase with thrombospondin motifs 8 isoform X1
NM_007037.5	NP_008968.4	A disintegrin and metalloproteinase with thrombospondin motifs 8 preproprotein
NM_007037.6	NP_008968.4	A disintegrin and metalloproteinase with thrombospondin motifs 8 preproprotein
NM_007037.4	NP_008968.4	A disintegrin and metalloproteinase with thrombospondin motifs 8 preproprotein

Pathways from BioSystems

Homologies

Canis lupus familiaris (dog)	ADAMTS8	XP_005620353.1
Danio rerio (zebrafish)	adamts8a	XP_698107.4
Xenopus tropicalis (tropical clawed frog)	adamts8	XP_002940685.2
Rattus norvegicus (Norway rat)	Adamts8	XP_003750503.1
Pan troglodytes (chimpanzee)	ADAMTS8	XP_522252.2
Bos taurus (cattle)	ADAMTS8	NP_001179254.1
Mus musculus (house mouse)	Adamts8	NP_038934.2
Gallus gallus (chicken)	ADAMTS8	XP_001232457.3
	ADAMTS8	XP_001112387.2
Danio rerio (zebrafish)	adamts15	XP_001341878.1
Homo sapiens (human)	ADAMTS8	NP_008968.4

Gene Ontology
Bibliography

Related articles in PubMed

Differentially regulated ADAMTS1, 8, and 18 in gastric adenocarcinoma.
Kilic MO, Aynekin B, Kara A, Icen D, Demircan K
Bratislavske lekarske listy118(2)71-76(2017)

Downregulation of ADAMTS8 by DNA Hypermethylation in Gastric Cancer and Its Clinical Significance.
Chen J, Zhang J, Li X, Zhang C, Zhang H, Jin J, Dai D
BioMed research international20165083841(2016)

Meta-analysis of genome-wide association studies identifies novel loci that influence cupping and the glaucomatous process.
Springelkamp H, H?hn R, Mishra A, Hysi PG, Khor CC, Loomis SJ, Bailey JN, Gibson J, Thorleifsson G, Janssen SF, Luo X, Ramdas WD, Vithana E, Nongpiur ME, Montgomery GW, Xu L, Mountain JE, Gharahkhani P, Lu Y, Amin N, Karssen LC, Sim KS, van Leeuwen EM, Iglesias AI, Verhoeven VJ, Hauser MA, Loon SC, Despriet DD, Nag A, Venturini C, Sanfilippo PG, Schillert A, Kang JH, Landers J, Jonasson F, Cree AJ, van Koolwijk LM, Rivadeneira F, Souzeau E, Jonsson V, Menon G, , Weinreb RN, de Jong PT, Oostra BA, Uitterlinden AG, Hofman A, Ennis S, Thorsteinsdottir U, Burdon KP, , , Spector TD, Mirshahi A, Saw SM, Vingerling JR, Teo YY, Haines JL, Wolfs RC, Lemij HG, Tai ES, Jansonius NM, Jonas JB, Cheng CY, Aung T, Viswanathan AC, Klaver CC, Craig JE, Macgregor S, Mackey DA, Lotery AJ, Stefansson K, Bergen AA, Young TL, Wiggs JL, Pfeiffer N, Wong TY, Pasquale LR, Hewitt AW, van Duijn CM, Hammond CJ
Nature communications54883(2014 Sep)

Genome-wide study reveals an important role of spontaneous autoimmunity, cardiomyocyte differentiation defect and anti-angiogenic activities in gender-specific gene expression in Keshan disease.
He S, Tan W, Wang S, Wu C, Wang P, Wang B, Su X, Zhao J, Guo X, Xiang Y
Chinese medical journal127(1)72-8(2014)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

This study showed that ADAMTS1, 8, and 18 are highly expressed in GC and its nodal metastases, suggesting important roles of these proteases in carcinogenesis and lymphatic metastasis. The findings from the present study indicate that these proteases may be promising candidates for novel and alternative treatments in GC (gastric cancer)
Title: Differentially regulated ADAMTS1, 8, and 18 in gastric adenocarcinoma.

ADAMTS8 hypermethylation is associated with decreased expression in gastric cancer.
Title: Downregulation of ADAMTS8 by DNA Hypermethylation in Gastric Cancer and Its Clinical Significance.

Study uncovers the tumor suppressive function of ADAMTS8 and its frequent methylation in certain tumors could be developed as a potential biomarker.
Title: The metalloprotease ADAMTS8 displays antitumor properties through antagonizing EGFR-MEK-ERK signaling and is silenced in carcinomas by CpG methylation.

ADAMTS 8, CCL23, and TNFSF15 are implicated in anti-angiogenic activities
Title: Genome-wide study reveals an important role of spontaneous autoimmunity, cardiomyocyte differentiation defect and anti-angiogenic activities in gender-specific gene expression in Keshan disease.

Observational study and genome-wide association study of gene-disease association. (HuGE Navigator)
Title: Human variation in alcohol response is influenced by variation in neuronal signaling genes.

The following ADAMTS8 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the ADAMTS8 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu05804	NM_007037.6 Latest version!	Homo sapiens ADAM metallopeptidase with thrombospondin type 1 motif 8 (ADAMTS8), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$449.50-$629.30 $899.00
OHu91914	XM_017017145.1 Latest version!	Homo sapiens ADAM metallopeptidase with thrombospondin type 1 motif 8 (ADAMTS8), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$475.30 $679.00
View Old Accession Versions >>
OHu05804	NM_007037.5	Homo sapiens ADAM metallopeptidase with thrombospondin type 1 motif 8 (ADAMTS8), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$449.50-$629.30 $899.00
OHu05804	NM_007037.4	Homo sapiens ADAM metallopeptidase with thrombospondin type 1 motif, 8 (ADAMTS8), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$449.50-$629.30 $899.00
Hide Old Accession Versions >>

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***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

ADAMTS8 ( NM_007037.5 ) cDNA ORF clone, Homo sapiens(Human) -> NP_008968.4 Homo sapiens ADAM metallopeptidase with thrombospondin type 1 motif 8 (ADAMTS8), mRNA.

Price & Availability↑

CloneID	OHu05804
Clone ID Related Accession (Same CDS sequence)	NM_007037.5 , NM_007037.6 , NM_007037.4
Accession Version	NM_007037.5	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2670bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-12-10
Organism	Homo sapiens(human)
Product	A disintegrin and metalloproteinase with thrombospondin motifs 8 preproprotein
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AF060153.1, AP002986.2, BX424609.2 and BC089435.1. This sequence is a reference standard in the RefSeqGene project. On Feb 27, 2016 this sequence version replaced NM_007037.4. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AF060153.1, SRR1660803.232015.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGCTCCCCG CCCCCGCCGC CCCCCGGTGG CCTCCGCTCC TGCTGCTGCT GCTGCTGCTG 
CTGCCGCTGG CCCGCGGCGC CCCGGCCCGG CCCGCAGCCG GGGGGCAGGC CTCGGAGCTG 
GTGGTGCCCA CGCGGTTGCC CGGCAGCGCG GGCGAGCTCG CGCTCCACCT GTCCGCCTTC 
GGCAAGGGCT TCGTGCTGCG CCTGGCGCCC GACGACAGCT TCCTAGCGCC CGAGTTCAAG 
ATCGAGCGCC TCGGGGGCTC CGGCCGGGCG ACCGGGGGCG AGCGGGGGCT GCGCGGCTGC 
TTCTTCTCCG GCACCGTGAA TGGGGAGCCC GAGTCGCTGG CGGCGGTCAG CCTGTGCCGC 
GGGCTGAGCG GCTCCTTCCT GCTGGACGGC GAGGAGTTCA CCATCCAGCC GCAGGGCGCG 
GGGGGCTCCC TGGCTCAGCC GCACCGCCTG CAGCGCTGGG GTCCCGCCGG AGCCCGCCCC 
CTCCCGCGAG GACCCGAGTG GGAGGTGGAG ACGGGAGAGG GTCAGAGGCA GGAGAGAGGA 
GACCACCAGG AGGACAGCGA GGAGGAGAGC CAAGAAGAGG AGGCAGAAGG CGCTAGCGAG 
CCGCCACCGC CCCTGGGGGC CACGAGTAGG ACCAAGCGGT TTGTGTCTGA GGCGCGCTTC 
GTGGAGACGC TGCTGGTGGC CGATGCGTCC ATGGCTGCCT TCTACGGGGC CGACCTGCAG 
AACCACATCC TGACGTTAAT GTCTGTGGCA GCCCGAATCT ACAAGCACCC CAGCATCAAG 
AATTCCATCA ACCTGATGGT GGTAAAAGTG CTGATCGTAG AAGATGAAAA ATGGGGCCCA 
GAGGTGTCCG ACAATGGGGG GCTTACACTG CGTAACTTCT GCAACTGGCA GCGGCGTTTC 
AACCAGCCCA GCGACCGCCA CCCAGAGCAC TACGACACGG CCATCCTGCT CACCAGACAG 
AACTTCTGTG GGCAGGAGGG GCTGTGTGAC ACCCTGGGTG TGGCAGACAT CGGGACCATT 
TGTGACCCCA ACAAAAGCTG CTCCGTGATC GAGGATGAGG GGCTCCAGGC GGCCCACACC 
CTGGCCCATG AACTAGGGCA CGTCCTCAGC ATGCCCCACG ACGACTCCAA GCCCTGCACA 
CGGCTCTTCG GGCCCATGGG CAAGCACCAC GTGATGGCAC CGCTGTTCGT CCACCTGAAC 
CAGACGCTGC CCTGGTCCCC CTGCAGCGCC ATGTATCTCA CAGAGCTTCT GGACGGCGGG 
CACGGAGACT GTCTCCTGGA TGCCCCTGCT GCGGCCCTGC CCCTCCCCAC AGGCCTCCCG 
GGCCGCATGG CCCTGTACCA GCTGGACCAG CAGTGCAGGC AGATCTTTGG GCCGGATTTC 
CGCCACTGCC CCAACACCTC TGCTCAGGAC GTCTGCGCCC AGCTTTGGTG CCACACTGAT 
GGGGCTGAGC CCCTGTGCCA CACGAAGAAT GGCAGCCTGC CCTGGGCTGA CGGCACGCCG 
TGCGGGCCTG GGCACCTCTG CTCAGAAGGC AGCTGTCTAC CTGAGGAGGA AGTGGAGAGG 
CCCAAGCCCG TGGCAGATGG AGGCTGGGCA CCGTGGGGAC CCTGGGGAGA ATGTTCTCGG 
ACCTGTGGAG GAGGAGTACA GTTTTCACAC CGTGAGTGCA AGGACCCCGA GCCTCAGAAT 
GGAGGAAGAT ACTGCCTGGG TCGGAGAGCC AAGTACCAGT CATGCCACAC GGAGGAATGC 
CCCCCTGACG GGAAAAGCTT CAGGGAGCAG CAGTGTGAGA AGTATAATGC CTACAATTAC 
ACTGACATGG ACGGGAATCT CCTGCAGTGG GTCCCCAAGT ATGCTGGGGT GTCCCCCCGG 
GACCGCTGCA AGTTGTTCTG CCGAGCCCGG GGGAGGAGCG AGTTCAAAGT GTTCGAGGCC 
AAGGTGATTG ATGGCACCCT GTGTGGGCCA GAAACACTGG CCATCTGTGT CCGTGGCCAG 
TGTGTCAAGG CCGGCTGTGA CCATGTGGTG GACTCGCCTC GGAAGCTGGA CAAATGCGGG 
GTGTGTGGGG GCAAAGGCAA CTCCTGCAGG AAGGTCTCCG GGTCCCTCAC CCCCACCAAT 
TATGGCTACA ATGACATTGT CACCATCCCA GCTGGTGCCA CTAATATTGA CGTGAAGCAG 
CGGAGCCACC CGGGTGTGCA GAACGATGGG AACTACCTGG CGCTGAAGAC GGCTGATGGG 
CAGTACCTGC TCAACGGCAA CCTGGCCATC TCTGCCATAG AGCAGGACAT CTTGGTGAAG 
GGGACCATCC TGAAGTACAG CGGCTCCATC GCCACCCTGG AGCGCCTGCA GAGCTTCCGG 
CCCTTGCCAG AGCCTCTGAC AGTGCAGCTC CTGACAGTCC CTGGCGAGGT CTTCCCCCCA 
AAAGTCAAAT ACACCTTCTT TGTTCCTAAT GACGTGGACT TTAGCATGCA GAGCAGCAAA 
GAGAGAGCAA CCACCAACAT CATCCAGCCG CTGCTCCACG CACAGTGGGT GCTGGGGGAC 
TGGTCTGAGT GCTCTAGCAC CTGCGGGGCC GGCTGGCAGA GGCGAACTGT AGAGTGCAGG 
GACCCCTCCG GCCAGGCCTC TGCCACCTGC AACAAGGCTC TGAAACCCGA GGATGCCAAG 
CCCTGCGAAA GCCAGCTGTG CCCCCTGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_008968.4
CDS	708..3377
Translation	MLPAPAAPRWPPLLLLLLLLLPLARGAPARPAAGGQASELVVPTRLPGSAGELALHLSAFGKGFVLRLAPDDSFLAPEFKIERLGGSGRATGGERGLRGCFFSGTVNGEPESLAAVSLCRGLSGSFLLDGEEFTIQPQGAGGSLAQPHRLQRWGPAGARPLPRGPEWEVETGEGQRQERGDHQEDSEEESQEEEAEGASEPPPPLGATSRTKRFVSEARFVETLLVADASMAAFYGADLQNHILTLMSVAARIYKHPSIKNSINLMVVKVLIVEDEKWGPEVSDNGGLTLRNFCNWQRRFNQPSDRHPEHYDTAILLTRQNFCGQEGLCDTLGVADIGTICDPNKSCSVIEDEGLQAAHTLAHELGHVLSMPHDDSKPCTRLFGPMGKHHVMAPLFVHLNQTLPWSPCSAMYLTELLDGGHGDCLLDAPAAALPLPTGLPGRMALYQLDQQCRQIFGPDFRHCPNTSAQDVCAQLWCHTDGAEPLCHTKNGSLPWADGTPCGPGHLCSEGSCLPEEEVERPKPVADGGWAPWGPWGECSRTCGGGVQFSHRECKDPEPQNGGRYCLGRRAKYQSCHTEECPPDGKSFREQQCEKYNAYNYTDMDGNLLQWVPKYAGVSPRDRCKLFCRARGRSEFKVFEAKVIDGTLCGPETLAICVRGQCVKAGCDHVVDSPRKLDKCGVCGGKGNSCRKVSGSLTPTNYGYNDIVTIPAGATNIDVKQRSHPGVQNDGNYLALKTADGQYLLNGNLAISAIEQDILVKGTILKYSGSIATLERLQSFRPLPEPLTVQLLTVPGEVFPPKVKYTFFVPNDVDFSMQSSKERATTNIIQPLLHAQWVLGDWSECSSTCGAGWQRRTVECRDPSGQASATCNKALKPEDAKPCESQLCPL

Target ORF information:

RefSeq Version	NM_007037.5
Organism	Homo sapiens(human)
Definition	Homo sapiens ADAM metallopeptidase with thrombospondin type 1 motif 8 (ADAMTS8), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_007037.5

ORF Insert Sequence:

ATGCTCCCCG CCCCCGCCGC CCCCCGGTGG CCTCCGCTCC TGCTGCTGCT GCTGCTGCTG 
CTGCCGCTGG CCCGCGGCGC CCCGGCCCGG CCCGCAGCCG GGGGGCAGGC CTCGGAGCTG 
GTGGTGCCCA CGCGGTTGCC CGGCAGCGCG GGCGAGCTCG CGCTCCACCT GTCCGCCTTC 
GGCAAGGGCT TCGTGCTGCG CCTGGCGCCC GACGACAGCT TCCTAGCGCC CGAGTTCAAG 
ATCGAGCGCC TCGGGGGCTC CGGCCGGGCG ACCGGGGGCG AGCGGGGGCT GCGCGGCTGC 
TTCTTCTCCG GCACCGTGAA TGGGGAGCCC GAGTCGCTGG CGGCGGTCAG CCTGTGCCGC 
GGGCTGAGCG GCTCCTTCCT GCTGGACGGC GAGGAGTTCA CCATCCAGCC GCAGGGCGCG 
GGGGGCTCCC TGGCTCAGCC GCACCGCCTG CAGCGCTGGG GTCCCGCCGG AGCCCGCCCC 
CTCCCGCGAG GACCCGAGTG GGAGGTGGAG ACGGGAGAGG GTCAGAGGCA GGAGAGAGGA 
GACCACCAGG AGGACAGCGA GGAGGAGAGC CAAGAAGAGG AGGCAGAAGG CGCTAGCGAG 
CCGCCACCGC CCCTGGGGGC CACGAGTAGG ACCAAGCGGT TTGTGTCTGA GGCGCGCTTC 
GTGGAGACGC TGCTGGTGGC CGATGCGTCC ATGGCTGCCT TCTACGGGGC CGACCTGCAG 
AACCACATCC TGACGTTAAT GTCTGTGGCA GCCCGAATCT ACAAGCACCC CAGCATCAAG 
AATTCCATCA ACCTGATGGT GGTAAAAGTG CTGATCGTAG AAGATGAAAA ATGGGGCCCA 
GAGGTGTCCG ACAATGGGGG GCTTACACTG CGTAACTTCT GCAACTGGCA GCGGCGTTTC 
AACCAGCCCA GCGACCGCCA CCCAGAGCAC TACGACACGG CCATCCTGCT CACCAGACAG 
AACTTCTGTG GGCAGGAGGG GCTGTGTGAC ACCCTGGGTG TGGCAGACAT CGGGACCATT 
TGTGACCCCA ACAAAAGCTG CTCCGTGATC GAGGATGAGG GGCTCCAGGC GGCCCACACC 
CTGGCCCATG AACTAGGGCA CGTCCTCAGC ATGCCCCACG ACGACTCCAA GCCCTGCACA 
CGGCTCTTCG GGCCCATGGG CAAGCACCAC GTGATGGCAC CGCTGTTCGT CCACCTGAAC 
CAGACGCTGC CCTGGTCCCC CTGCAGCGCC ATGTATCTCA CAGAGCTTCT GGACGGCGGG 
CACGGAGACT GTCTCCTGGA TGCCCCTGCT GCGGCCCTGC CCCTCCCCAC AGGCCTCCCG 
GGCCGCATGG CCCTGTACCA GCTGGACCAG CAGTGCAGGC AGATCTTTGG GCCGGATTTC 
CGCCACTGCC CCAACACCTC TGCTCAGGAC GTCTGCGCCC AGCTTTGGTG CCACACTGAT 
GGGGCTGAGC CCCTGTGCCA CACGAAGAAT GGCAGCCTGC CCTGGGCTGA CGGCACGCCG 
TGCGGGCCTG GGCACCTCTG CTCAGAAGGC AGCTGTCTAC CTGAGGAGGA AGTGGAGAGG 
CCCAAGCCCG TGGCAGATGG AGGCTGGGCA CCGTGGGGAC CCTGGGGAGA ATGTTCTCGG 
ACCTGTGGAG GAGGAGTACA GTTTTCACAC CGTGAGTGCA AGGACCCCGA GCCTCAGAAT 
GGAGGAAGAT ACTGCCTGGG TCGGAGAGCC AAGTACCAGT CATGCCACAC GGAGGAATGC 
CCCCCTGACG GGAAAAGCTT CAGGGAGCAG CAGTGTGAGA AGTATAATGC CTACAATTAC 
ACTGACATGG ACGGGAATCT CCTGCAGTGG GTCCCCAAGT ATGCTGGGGT GTCCCCCCGG 
GACCGCTGCA AGTTGTTCTG CCGAGCCCGG GGGAGGAGCG AGTTCAAAGT GTTCGAGGCC 
AAGGTGATTG ATGGCACCCT GTGTGGGCCA GAAACACTGG CCATCTGTGT CCGTGGCCAG 
TGTGTCAAGG CCGGCTGTGA CCATGTGGTG GACTCGCCTC GGAAGCTGGA CAAATGCGGG 
GTGTGTGGGG GCAAAGGCAA CTCCTGCAGG AAGGTCTCCG GGTCCCTCAC CCCCACCAAT 
TATGGCTACA ATGACATTGT CACCATCCCA GCTGGTGCCA CTAATATTGA CGTGAAGCAG 
CGGAGCCACC CGGGTGTGCA GAACGATGGG AACTACCTGG CGCTGAAGAC GGCTGATGGG 
CAGTACCTGC TCAACGGCAA CCTGGCCATC TCTGCCATAG AGCAGGACAT CTTGGTGAAG 
GGGACCATCC TGAAGTACAG CGGCTCCATC GCCACCCTGG AGCGCCTGCA GAGCTTCCGG 
CCCTTGCCAG AGCCTCTGAC AGTGCAGCTC CTGACAGTCC CTGGCGAGGT CTTCCCCCCA 
AAAGTCAAAT ACACCTTCTT TGTTCCTAAT GACGTGGACT TTAGCATGCA GAGCAGCAAA 
GAGAGAGCAA CCACCAACAT CATCCAGCCG CTGCTCCACG CACAGTGGGT GCTGGGGGAC 
TGGTCTGAGT GCTCTAGCAC CTGCGGGGCC GGCTGGCAGA GGCGAACTGT AGAGTGCAGG 
GACCCCTCCG GCCAGGCCTC TGCCACCTGC AACAAGGCTC TGAAACCCGA GGATGCCAAG 
CCCTGCGAAA GCCAGCTGTG CCCCCTGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

ADAMTS8 ( NM_007037.6 ) cDNA ORF clone, Homo sapiens(Human) -> NP_008968.4 Homo sapiens ADAM metallopeptidase with thrombospondin type 1 motif 8 (ADAMTS8), mRNA.

Price & Availability↑

CloneID	OHu05804
Clone ID Related Accession (Same CDS sequence)	NM_007037.5 , NM_007037.6 , NM_007037.4
Accession Version	NM_007037.6 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2670bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-08-21
Organism	Homo sapiens(human)
Product	A disintegrin and metalloproteinase with thrombospondin motifs 8 preproprotein
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AF060153.1, BX424609.2, AP002986.2 and BC089435.1. This sequence is a reference standard in the RefSeqGene project. On Nov 22, 2018 this sequence version replaced NM_007037.5. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AF060153.1, SRR1660803.232015.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000257359.7/ ENSP00000257359.6 RefSeq Select criteria :: based on conservation, expression, longest protein ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGCTCCCCG CCCCCGCCGC CCCCCGGTGG CCTCCGCTCC TGCTGCTGCT GCTGCTGCTG 
CTGCCGCTGG CCCGCGGCGC CCCGGCCCGG CCCGCAGCCG GGGGGCAGGC CTCGGAGCTG 
GTGGTGCCCA CGCGGTTGCC CGGCAGCGCG GGCGAGCTCG CGCTCCACCT GTCCGCCTTC 
GGCAAGGGCT TCGTGCTGCG CCTGGCGCCC GACGACAGCT TCCTAGCGCC CGAGTTCAAG 
ATCGAGCGCC TCGGGGGCTC CGGCCGGGCG ACCGGGGGCG AGCGGGGGCT GCGCGGCTGC 
TTCTTCTCCG GCACCGTGAA TGGGGAGCCC GAGTCGCTGG CGGCGGTCAG CCTGTGCCGC 
GGGCTGAGCG GCTCCTTCCT GCTGGACGGC GAGGAGTTCA CCATCCAGCC GCAGGGCGCG 
GGGGGCTCCC TGGCTCAGCC GCACCGCCTG CAGCGCTGGG GTCCCGCCGG AGCCCGCCCC 
CTCCCGCGAG GACCCGAGTG GGAGGTGGAG ACGGGAGAGG GTCAGAGGCA GGAGAGAGGA 
GACCACCAGG AGGACAGCGA GGAGGAGAGC CAAGAAGAGG AGGCAGAAGG CGCTAGCGAG 
CCGCCACCGC CCCTGGGGGC CACGAGTAGG ACCAAGCGGT TTGTGTCTGA GGCGCGCTTC 
GTGGAGACGC TGCTGGTGGC CGATGCGTCC ATGGCTGCCT TCTACGGGGC CGACCTGCAG 
AACCACATCC TGACGTTAAT GTCTGTGGCA GCCCGAATCT ACAAGCACCC CAGCATCAAG 
AATTCCATCA ACCTGATGGT GGTAAAAGTG CTGATCGTAG AAGATGAAAA ATGGGGCCCA 
GAGGTGTCCG ACAATGGGGG GCTTACACTG CGTAACTTCT GCAACTGGCA GCGGCGTTTC 
AACCAGCCCA GCGACCGCCA CCCAGAGCAC TACGACACGG CCATCCTGCT CACCAGACAG 
AACTTCTGTG GGCAGGAGGG GCTGTGTGAC ACCCTGGGTG TGGCAGACAT CGGGACCATT 
TGTGACCCCA ACAAAAGCTG CTCCGTGATC GAGGATGAGG GGCTCCAGGC GGCCCACACC 
CTGGCCCATG AACTAGGGCA CGTCCTCAGC ATGCCCCACG ACGACTCCAA GCCCTGCACA 
CGGCTCTTCG GGCCCATGGG CAAGCACCAC GTGATGGCAC CGCTGTTCGT CCACCTGAAC 
CAGACGCTGC CCTGGTCCCC CTGCAGCGCC ATGTATCTCA CAGAGCTTCT GGACGGCGGG 
CACGGAGACT GTCTCCTGGA TGCCCCTGCT GCGGCCCTGC CCCTCCCCAC AGGCCTCCCG 
GGCCGCATGG CCCTGTACCA GCTGGACCAG CAGTGCAGGC AGATCTTTGG GCCGGATTTC 
CGCCACTGCC CCAACACCTC TGCTCAGGAC GTCTGCGCCC AGCTTTGGTG CCACACTGAT 
GGGGCTGAGC CCCTGTGCCA CACGAAGAAT GGCAGCCTGC CCTGGGCTGA CGGCACGCCG 
TGCGGGCCTG GGCACCTCTG CTCAGAAGGC AGCTGTCTAC CTGAGGAGGA AGTGGAGAGG 
CCCAAGCCCG TGGCAGATGG AGGCTGGGCA CCGTGGGGAC CCTGGGGAGA ATGTTCTCGG 
ACCTGTGGAG GAGGAGTACA GTTTTCACAC CGTGAGTGCA AGGACCCCGA GCCTCAGAAT 
GGAGGAAGAT ACTGCCTGGG TCGGAGAGCC AAGTACCAGT CATGCCACAC GGAGGAATGC 
CCCCCTGACG GGAAAAGCTT CAGGGAGCAG CAGTGTGAGA AGTATAATGC CTACAATTAC 
ACTGACATGG ACGGGAATCT CCTGCAGTGG GTCCCCAAGT ATGCTGGGGT GTCCCCCCGG 
GACCGCTGCA AGTTGTTCTG CCGAGCCCGG GGGAGGAGCG AGTTCAAAGT GTTCGAGGCC 
AAGGTGATTG ATGGCACCCT GTGTGGGCCA GAAACACTGG CCATCTGTGT CCGTGGCCAG 
TGTGTCAAGG CCGGCTGTGA CCATGTGGTG GACTCGCCTC GGAAGCTGGA CAAATGCGGG 
GTGTGTGGGG GCAAAGGCAA CTCCTGCAGG AAGGTCTCCG GGTCCCTCAC CCCCACCAAT 
TATGGCTACA ATGACATTGT CACCATCCCA GCTGGTGCCA CTAATATTGA CGTGAAGCAG 
CGGAGCCACC CGGGTGTGCA GAACGATGGG AACTACCTGG CGCTGAAGAC GGCTGATGGG 
CAGTACCTGC TCAACGGCAA CCTGGCCATC TCTGCCATAG AGCAGGACAT CTTGGTGAAG 
GGGACCATCC TGAAGTACAG CGGCTCCATC GCCACCCTGG AGCGCCTGCA GAGCTTCCGG 
CCCTTGCCAG AGCCTCTGAC AGTGCAGCTC CTGACAGTCC CTGGCGAGGT CTTCCCCCCA 
AAAGTCAAAT ACACCTTCTT TGTTCCTAAT GACGTGGACT TTAGCATGCA GAGCAGCAAA 
GAGAGAGCAA CCACCAACAT CATCCAGCCG CTGCTCCACG CACAGTGGGT GCTGGGGGAC 
TGGTCTGAGT GCTCTAGCAC CTGCGGGGCC GGCTGGCAGA GGCGAACTGT AGAGTGCAGG 
GACCCCTCCG GCCAGGCCTC TGCCACCTGC AACAAGGCTC TGAAACCCGA GGATGCCAAG 
CCCTGCGAAA GCCAGCTGTG CCCCCTGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_008968.4
CDS	324..2993
Translation	MLPAPAAPRWPPLLLLLLLLLPLARGAPARPAAGGQASELVVPTRLPGSAGELALHLSAFGKGFVLRLAPDDSFLAPEFKIERLGGSGRATGGERGLRGCFFSGTVNGEPESLAAVSLCRGLSGSFLLDGEEFTIQPQGAGGSLAQPHRLQRWGPAGARPLPRGPEWEVETGEGQRQERGDHQEDSEEESQEEEAEGASEPPPPLGATSRTKRFVSEARFVETLLVADASMAAFYGADLQNHILTLMSVAARIYKHPSIKNSINLMVVKVLIVEDEKWGPEVSDNGGLTLRNFCNWQRRFNQPSDRHPEHYDTAILLTRQNFCGQEGLCDTLGVADIGTICDPNKSCSVIEDEGLQAAHTLAHELGHVLSMPHDDSKPCTRLFGPMGKHHVMAPLFVHLNQTLPWSPCSAMYLTELLDGGHGDCLLDAPAAALPLPTGLPGRMALYQLDQQCRQIFGPDFRHCPNTSAQDVCAQLWCHTDGAEPLCHTKNGSLPWADGTPCGPGHLCSEGSCLPEEEVERPKPVADGGWAPWGPWGECSRTCGGGVQFSHRECKDPEPQNGGRYCLGRRAKYQSCHTEECPPDGKSFREQQCEKYNAYNYTDMDGNLLQWVPKYAGVSPRDRCKLFCRARGRSEFKVFEAKVIDGTLCGPETLAICVRGQCVKAGCDHVVDSPRKLDKCGVCGGKGNSCRKVSGSLTPTNYGYNDIVTIPAGATNIDVKQRSHPGVQNDGNYLALKTADGQYLLNGNLAISAIEQDILVKGTILKYSGSIATLERLQSFRPLPEPLTVQLLTVPGEVFPPKVKYTFFVPNDVDFSMQSSKERATTNIIQPLLHAQWVLGDWSECSSTCGAGWQRRTVECRDPSGQASATCNKALKPEDAKPCESQLCPL

Target ORF information:

RefSeq Version	NM_007037.6
Organism	Homo sapiens(human)
Definition	Homo sapiens ADAM metallopeptidase with thrombospondin type 1 motif 8 (ADAMTS8), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_007037.6

ORF Insert Sequence:

ATGCTCCCCG CCCCCGCCGC CCCCCGGTGG CCTCCGCTCC TGCTGCTGCT GCTGCTGCTG 
CTGCCGCTGG CCCGCGGCGC CCCGGCCCGG CCCGCAGCCG GGGGGCAGGC CTCGGAGCTG 
GTGGTGCCCA CGCGGTTGCC CGGCAGCGCG GGCGAGCTCG CGCTCCACCT GTCCGCCTTC 
GGCAAGGGCT TCGTGCTGCG CCTGGCGCCC GACGACAGCT TCCTAGCGCC CGAGTTCAAG 
ATCGAGCGCC TCGGGGGCTC CGGCCGGGCG ACCGGGGGCG AGCGGGGGCT GCGCGGCTGC 
TTCTTCTCCG GCACCGTGAA TGGGGAGCCC GAGTCGCTGG CGGCGGTCAG CCTGTGCCGC 
GGGCTGAGCG GCTCCTTCCT GCTGGACGGC GAGGAGTTCA CCATCCAGCC GCAGGGCGCG 
GGGGGCTCCC TGGCTCAGCC GCACCGCCTG CAGCGCTGGG GTCCCGCCGG AGCCCGCCCC 
CTCCCGCGAG GACCCGAGTG GGAGGTGGAG ACGGGAGAGG GTCAGAGGCA GGAGAGAGGA 
GACCACCAGG AGGACAGCGA GGAGGAGAGC CAAGAAGAGG AGGCAGAAGG CGCTAGCGAG 
CCGCCACCGC CCCTGGGGGC CACGAGTAGG ACCAAGCGGT TTGTGTCTGA GGCGCGCTTC 
GTGGAGACGC TGCTGGTGGC CGATGCGTCC ATGGCTGCCT TCTACGGGGC CGACCTGCAG 
AACCACATCC TGACGTTAAT GTCTGTGGCA GCCCGAATCT ACAAGCACCC CAGCATCAAG 
AATTCCATCA ACCTGATGGT GGTAAAAGTG CTGATCGTAG AAGATGAAAA ATGGGGCCCA 
GAGGTGTCCG ACAATGGGGG GCTTACACTG CGTAACTTCT GCAACTGGCA GCGGCGTTTC 
AACCAGCCCA GCGACCGCCA CCCAGAGCAC TACGACACGG CCATCCTGCT CACCAGACAG 
AACTTCTGTG GGCAGGAGGG GCTGTGTGAC ACCCTGGGTG TGGCAGACAT CGGGACCATT 
TGTGACCCCA ACAAAAGCTG CTCCGTGATC GAGGATGAGG GGCTCCAGGC GGCCCACACC 
CTGGCCCATG AACTAGGGCA CGTCCTCAGC ATGCCCCACG ACGACTCCAA GCCCTGCACA 
CGGCTCTTCG GGCCCATGGG CAAGCACCAC GTGATGGCAC CGCTGTTCGT CCACCTGAAC 
CAGACGCTGC CCTGGTCCCC CTGCAGCGCC ATGTATCTCA CAGAGCTTCT GGACGGCGGG 
CACGGAGACT GTCTCCTGGA TGCCCCTGCT GCGGCCCTGC CCCTCCCCAC AGGCCTCCCG 
GGCCGCATGG CCCTGTACCA GCTGGACCAG CAGTGCAGGC AGATCTTTGG GCCGGATTTC 
CGCCACTGCC CCAACACCTC TGCTCAGGAC GTCTGCGCCC AGCTTTGGTG CCACACTGAT 
GGGGCTGAGC CCCTGTGCCA CACGAAGAAT GGCAGCCTGC CCTGGGCTGA CGGCACGCCG 
TGCGGGCCTG GGCACCTCTG CTCAGAAGGC AGCTGTCTAC CTGAGGAGGA AGTGGAGAGG 
CCCAAGCCCG TGGCAGATGG AGGCTGGGCA CCGTGGGGAC CCTGGGGAGA ATGTTCTCGG 
ACCTGTGGAG GAGGAGTACA GTTTTCACAC CGTGAGTGCA AGGACCCCGA GCCTCAGAAT 
GGAGGAAGAT ACTGCCTGGG TCGGAGAGCC AAGTACCAGT CATGCCACAC GGAGGAATGC 
CCCCCTGACG GGAAAAGCTT CAGGGAGCAG CAGTGTGAGA AGTATAATGC CTACAATTAC 
ACTGACATGG ACGGGAATCT CCTGCAGTGG GTCCCCAAGT ATGCTGGGGT GTCCCCCCGG 
GACCGCTGCA AGTTGTTCTG CCGAGCCCGG GGGAGGAGCG AGTTCAAAGT GTTCGAGGCC 
AAGGTGATTG ATGGCACCCT GTGTGGGCCA GAAACACTGG CCATCTGTGT CCGTGGCCAG 
TGTGTCAAGG CCGGCTGTGA CCATGTGGTG GACTCGCCTC GGAAGCTGGA CAAATGCGGG 
GTGTGTGGGG GCAAAGGCAA CTCCTGCAGG AAGGTCTCCG GGTCCCTCAC CCCCACCAAT 
TATGGCTACA ATGACATTGT CACCATCCCA GCTGGTGCCA CTAATATTGA CGTGAAGCAG 
CGGAGCCACC CGGGTGTGCA GAACGATGGG AACTACCTGG CGCTGAAGAC GGCTGATGGG 
CAGTACCTGC TCAACGGCAA CCTGGCCATC TCTGCCATAG AGCAGGACAT CTTGGTGAAG 
GGGACCATCC TGAAGTACAG CGGCTCCATC GCCACCCTGG AGCGCCTGCA GAGCTTCCGG 
CCCTTGCCAG AGCCTCTGAC AGTGCAGCTC CTGACAGTCC CTGGCGAGGT CTTCCCCCCA 
AAAGTCAAAT ACACCTTCTT TGTTCCTAAT GACGTGGACT TTAGCATGCA GAGCAGCAAA 
GAGAGAGCAA CCACCAACAT CATCCAGCCG CTGCTCCACG CACAGTGGGT GCTGGGGGAC 
TGGTCTGAGT GCTCTAGCAC CTGCGGGGCC GGCTGGCAGA GGCGAACTGT AGAGTGCAGG 
GACCCCTCCG GCCAGGCCTC TGCCACCTGC AACAAGGCTC TGAAACCCGA GGATGCCAAG 
CCCTGCGAAA GCCAGCTGTG CCCCCTGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

ADAMTS8 ( NM_007037.4 ) cDNA ORF clone, Homo sapiens(Human) -> NP_008968.4 Homo sapiens ADAM metallopeptidase with thrombospondin type 1 motif, 8 (ADAMTS8), mRNA.

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CloneID	OHu05804
Clone ID Related Accession (Same CDS sequence)	NM_007037.5 , NM_007037.6 , NM_007037.4
Accession Version	NM_007037.4	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2670bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2015-03-14
Organism	Homo sapiens(Human)
Product	A disintegrin and metalloproteinase with thrombospondin motifs 8 preproprotein
Comment

ATGCTCCCCG CCCCCGCCGC CCCCCGGTGG CCTCCGCTCC TGCTGCTGCT GCTGCTGCTG 
CTGCCGCTGG CCCGCGGCGC CCCGGCCCGG CCCGCAGCCG GGGGGCAGGC CTCGGAGCTG 
GTGGTGCCCA CGCGGTTGCC CGGCAGCGCG GGCGAGCTCG CGCTCCACCT GTCCGCCTTC 
GGCAAGGGCT TCGTGCTGCG CCTGGCGCCC GACGACAGCT TCCTAGCGCC CGAGTTCAAG 
ATCGAGCGCC TCGGGGGCTC CGGCCGGGCG ACCGGGGGCG AGCGGGGGCT GCGCGGCTGC 
TTCTTCTCCG GCACCGTGAA TGGGGAGCCC GAGTCGCTGG CGGCGGTCAG CCTGTGCCGC 
GGGCTGAGCG GCTCCTTCCT GCTGGACGGC GAGGAGTTCA CCATCCAGCC GCAGGGCGCG 
GGGGGCTCCC TGGCTCAGCC GCACCGCCTG CAGCGCTGGG GTCCCGCCGG AGCCCGCCCC 
CTCCCGCGAG GACCCGAGTG GGAGGTGGAG ACGGGAGAGG GTCAGAGGCA GGAGAGAGGA 
GACCACCAGG AGGACAGCGA GGAGGAGAGC CAAGAAGAGG AGGCAGAAGG CGCTAGCGAG 
CCGCCACCGC CCCTGGGGGC CACGAGTAGG ACCAAGCGGT TTGTGTCTGA GGCGCGCTTC 
GTGGAGACGC TGCTGGTGGC CGATGCGTCC ATGGCTGCCT TCTACGGGGC CGACCTGCAG 
AACCACATCC TGACGTTAAT GTCTGTGGCA GCCCGAATCT ACAAGCACCC CAGCATCAAG 
AATTCCATCA ACCTGATGGT GGTAAAAGTG CTGATCGTAG AAGATGAAAA ATGGGGCCCA 
GAGGTGTCCG ACAATGGGGG GCTTACACTG CGTAACTTCT GCAACTGGCA GCGGCGTTTC 
AACCAGCCCA GCGACCGCCA CCCAGAGCAC TACGACACGG CCATCCTGCT CACCAGACAG 
AACTTCTGTG GGCAGGAGGG GCTGTGTGAC ACCCTGGGTG TGGCAGACAT CGGGACCATT 
TGTGACCCCA ACAAAAGCTG CTCCGTGATC GAGGATGAGG GGCTCCAGGC GGCCCACACC 
CTGGCCCATG AACTAGGGCA CGTCCTCAGC ATGCCCCACG ACGACTCCAA GCCCTGCACA 
CGGCTCTTCG GGCCCATGGG CAAGCACCAC GTGATGGCAC CGCTGTTCGT CCACCTGAAC 
CAGACGCTGC CCTGGTCCCC CTGCAGCGCC ATGTATCTCA CAGAGCTTCT GGACGGCGGG 
CACGGAGACT GTCTCCTGGA TGCCCCTGCT GCGGCCCTGC CCCTCCCCAC AGGCCTCCCG 
GGCCGCATGG CCCTGTACCA GCTGGACCAG CAGTGCAGGC AGATCTTTGG GCCGGATTTC 
CGCCACTGCC CCAACACCTC TGCTCAGGAC GTCTGCGCCC AGCTTTGGTG CCACACTGAT 
GGGGCTGAGC CCCTGTGCCA CACGAAGAAT GGCAGCCTGC CCTGGGCTGA CGGCACGCCG 
TGCGGGCCTG GGCACCTCTG CTCAGAAGGC AGCTGTCTAC CTGAGGAGGA AGTGGAGAGG 
CCCAAGCCCG TGGCAGATGG AGGCTGGGCA CCGTGGGGAC CCTGGGGAGA ATGTTCTCGG 
ACCTGTGGAG GAGGAGTACA GTTTTCACAC CGTGAGTGCA AGGACCCCGA GCCTCAGAAT 
GGAGGAAGAT ACTGCCTGGG TCGGAGAGCC AAGTACCAGT CATGCCACAC GGAGGAATGC 
CCCCCTGACG GGAAAAGCTT CAGGGAGCAG CAGTGTGAGA AGTATAATGC CTACAATTAC 
ACTGACATGG ACGGGAATCT CCTGCAGTGG GTCCCCAAGT ATGCTGGGGT GTCCCCCCGG 
GACCGCTGCA AGTTGTTCTG CCGAGCCCGG GGGAGGAGCG AGTTCAAAGT GTTCGAGGCC 
AAGGTGATTG ATGGCACCCT GTGTGGGCCA GAAACACTGG CCATCTGTGT CCGTGGCCAG 
TGTGTCAAGG CCGGCTGTGA CCATGTGGTG GACTCGCCTC GGAAGCTGGA CAAATGCGGG 
GTGTGTGGGG GCAAAGGCAA CTCCTGCAGG AAGGTCTCCG GGTCCCTCAC CCCCACCAAT 
TATGGCTACA ATGACATTGT CACCATCCCA GCTGGTGCCA CTAATATTGA CGTGAAGCAG 
CGGAGCCACC CGGGTGTGCA GAACGATGGG AACTACCTGG CGCTGAAGAC GGCTGATGGG 
CAGTACCTGC TCAACGGCAA CCTGGCCATC TCTGCCATAG AGCAGGACAT CTTGGTGAAG 
GGGACCATCC TGAAGTACAG CGGCTCCATC GCCACCCTGG AGCGCCTGCA GAGCTTCCGG 
CCCTTGCCAG AGCCTCTGAC AGTGCAGCTC CTGACAGTCC CTGGCGAGGT CTTCCCCCCA 
AAAGTCAAAT ACACCTTCTT TGTTCCTAAT GACGTGGACT TTAGCATGCA GAGCAGCAAA 
GAGAGAGCAA CCACCAACAT CATCCAGCCG CTGCTCCACG CACAGTGGGT GCTGGGGGAC 
TGGTCTGAGT GCTCTAGCAC CTGCGGGGCC GGCTGGCAGA GGCGAACTGT AGAGTGCAGG 
GACCCCTCCG GCCAGGCCTC TGCCACCTGC AACAAGGCTC TGAAACCCGA GGATGCCAAG 
CCCTGCGAAA GCCAGCTGTG CCCCCTGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq

NP_008968.4

Translation

MLPAPAAPRWPPLLLLLLLLLPLARGAPARPAAGGQASELVVPTRLPGSAGELALHLSAFGKGFVLRLAPDDSFLAPEFKIERLGGSGRATGGERGLRGCFFSGTVNGEPESLAAVSLCRGLSGSFLLDGEEFTIQPQGAGGSLAQPHRLQRWGPAGARPLPRGPEWEVETGEGQRQERGDHQEDSEEESQEEEAEGASEPPPPLGATSRTKRFVSEARFVETLLVADASMAAFYGADLQNHILTLMSVAARIYKHPSIKNSINLMVVKVLIVEDEKWGPEVSDNGGLTLRNFCNWQRRFNQPSDRHPEHYDTAILLTRQNFCGQEGLCDTLGVADIGTICDPNKSCSVIEDEGLQAAHTLAHELGHVLSMPHDDSKPCTRLFGPMGKHHVMAPLFVHLNQTLPWSPCSAMYLTELLDGGHGDCLLDAPAAALPLPTGLPGRMALYQLDQQCRQIFGPDFRHCPNTSAQDVCAQLWCHTDGAEPLCHTKNGSLPWADGTPCGPGHLCSEGSCLPEEEVERPKPVADGGWAPWGPWGECSRTCGGGVQFSHRECKDPEPQNGGRYCLGRRAKYQSCHTEECPPDGKSFREQQCEKYNAYNYTDMDGNLLQWVPKYAGVSPRDRCKLFCRARGRSEFKVFEAKVIDGTLCGPETLAICVRGQCVKAGCDHVVDSPRKLDKCGVCGGKGNSCRKVSGSLTPTNYGYNDIVTIPAGATNIDVKQRSHPGVQNDGNYLALKTADGQYLLNGNLAISAIEQDILVKGTILKYSGSIATLERLQSFRPLPEPLTVQLLTVPGEVFPPKVKYTFFVPNDVDFSMQSSKERATTNIIQPLLHAQWVLGDWSECSSTCGAGWQRRTVECRDPSGQASATCNKALKPEDAKPCESQLCPL

Target ORF information:

RefSeq Version	NM_007037.4
Organism	Homo sapiens(Human)
Definition	Homo sapiens ADAM metallopeptidase with thrombospondin type 1 motif, 8 (ADAMTS8), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_007037.4

ORF Insert Sequence:

ATGCTCCCCG CCCCCGCCGC CCCCCGGTGG CCTCCGCTCC TGCTGCTGCT GCTGCTGCTG 
CTGCCGCTGG CCCGCGGCGC CCCGGCCCGG CCCGCAGCCG GGGGGCAGGC CTCGGAGCTG 
GTGGTGCCCA CGCGGTTGCC CGGCAGCGCG GGCGAGCTCG CGCTCCACCT GTCCGCCTTC 
GGCAAGGGCT TCGTGCTGCG CCTGGCGCCC GACGACAGCT TCCTAGCGCC CGAGTTCAAG 
ATCGAGCGCC TCGGGGGCTC CGGCCGGGCG ACCGGGGGCG AGCGGGGGCT GCGCGGCTGC 
TTCTTCTCCG GCACCGTGAA TGGGGAGCCC GAGTCGCTGG CGGCGGTCAG CCTGTGCCGC 
GGGCTGAGCG GCTCCTTCCT GCTGGACGGC GAGGAGTTCA CCATCCAGCC GCAGGGCGCG 
GGGGGCTCCC TGGCTCAGCC GCACCGCCTG CAGCGCTGGG GTCCCGCCGG AGCCCGCCCC 
CTCCCGCGAG GACCCGAGTG GGAGGTGGAG ACGGGAGAGG GTCAGAGGCA GGAGAGAGGA 
GACCACCAGG AGGACAGCGA GGAGGAGAGC CAAGAAGAGG AGGCAGAAGG CGCTAGCGAG 
CCGCCACCGC CCCTGGGGGC CACGAGTAGG ACCAAGCGGT TTGTGTCTGA GGCGCGCTTC 
GTGGAGACGC TGCTGGTGGC CGATGCGTCC ATGGCTGCCT TCTACGGGGC CGACCTGCAG 
AACCACATCC TGACGTTAAT GTCTGTGGCA GCCCGAATCT ACAAGCACCC CAGCATCAAG 
AATTCCATCA ACCTGATGGT GGTAAAAGTG CTGATCGTAG AAGATGAAAA ATGGGGCCCA 
GAGGTGTCCG ACAATGGGGG GCTTACACTG CGTAACTTCT GCAACTGGCA GCGGCGTTTC 
AACCAGCCCA GCGACCGCCA CCCAGAGCAC TACGACACGG CCATCCTGCT CACCAGACAG 
AACTTCTGTG GGCAGGAGGG GCTGTGTGAC ACCCTGGGTG TGGCAGACAT CGGGACCATT 
TGTGACCCCA ACAAAAGCTG CTCCGTGATC GAGGATGAGG GGCTCCAGGC GGCCCACACC 
CTGGCCCATG AACTAGGGCA CGTCCTCAGC ATGCCCCACG ACGACTCCAA GCCCTGCACA 
CGGCTCTTCG GGCCCATGGG CAAGCACCAC GTGATGGCAC CGCTGTTCGT CCACCTGAAC 
CAGACGCTGC CCTGGTCCCC CTGCAGCGCC ATGTATCTCA CAGAGCTTCT GGACGGCGGG 
CACGGAGACT GTCTCCTGGA TGCCCCTGCT GCGGCCCTGC CCCTCCCCAC AGGCCTCCCG 
GGCCGCATGG CCCTGTACCA GCTGGACCAG CAGTGCAGGC AGATCTTTGG GCCGGATTTC 
CGCCACTGCC CCAACACCTC TGCTCAGGAC GTCTGCGCCC AGCTTTGGTG CCACACTGAT 
GGGGCTGAGC CCCTGTGCCA CACGAAGAAT GGCAGCCTGC CCTGGGCTGA CGGCACGCCG 
TGCGGGCCTG GGCACCTCTG CTCAGAAGGC AGCTGTCTAC CTGAGGAGGA AGTGGAGAGG 
CCCAAGCCCG TGGCAGATGG AGGCTGGGCA CCGTGGGGAC CCTGGGGAGA ATGTTCTCGG 
ACCTGTGGAG GAGGAGTACA GTTTTCACAC CGTGAGTGCA AGGACCCCGA GCCTCAGAAT 
GGAGGAAGAT ACTGCCTGGG TCGGAGAGCC AAGTACCAGT CATGCCACAC GGAGGAATGC 
CCCCCTGACG GGAAAAGCTT CAGGGAGCAG CAGTGTGAGA AGTATAATGC CTACAATTAC 
ACTGACATGG ACGGGAATCT CCTGCAGTGG GTCCCCAAGT ATGCTGGGGT GTCCCCCCGG 
GACCGCTGCA AGTTGTTCTG CCGAGCCCGG GGGAGGAGCG AGTTCAAAGT GTTCGAGGCC 
AAGGTGATTG ATGGCACCCT GTGTGGGCCA GAAACACTGG CCATCTGTGT CCGTGGCCAG 
TGTGTCAAGG CCGGCTGTGA CCATGTGGTG GACTCGCCTC GGAAGCTGGA CAAATGCGGG 
GTGTGTGGGG GCAAAGGCAA CTCCTGCAGG AAGGTCTCCG GGTCCCTCAC CCCCACCAAT 
TATGGCTACA ATGACATTGT CACCATCCCA GCTGGTGCCA CTAATATTGA CGTGAAGCAG 
CGGAGCCACC CGGGTGTGCA GAACGATGGG AACTACCTGG CGCTGAAGAC GGCTGATGGG 
CAGTACCTGC TCAACGGCAA CCTGGCCATC TCTGCCATAG AGCAGGACAT CTTGGTGAAG 
GGGACCATCC TGAAGTACAG CGGCTCCATC GCCACCCTGG AGCGCCTGCA GAGCTTCCGG 
CCCTTGCCAG AGCCTCTGAC AGTGCAGCTC CTGACAGTCC CTGGCGAGGT CTTCCCCCCA 
AAAGTCAAAT ACACCTTCTT TGTTCCTAAT GACGTGGACT TTAGCATGCA GAGCAGCAAA 
GAGAGAGCAA CCACCAACAT CATCCAGCCG CTGCTCCACG CACAGTGGGT GCTGGGGGAC 
TGGTCTGAGT GCTCTAGCAC CTGCGGGGCC GGCTGGCAGA GGCGAACTGT AGAGTGCAGG 
GACCCCTCCG GCCAGGCCTC TGCCACCTGC AACAAGGCTC TGAAACCCGA GGATGCCAAG 
CCCTGCGAAA GCCAGCTGTG CCCCCTGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

ADAMTS8 ( XM_017017145.1 ) cDNA ORF clone, Homo sapiens(Human) -> XP_016872634.1 Homo sapiens ADAM metallopeptidase with thrombospondin type 1 motif 8 (ADAMTS8), transcript variant X1, mRNA.

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CloneID	OHu91914
Clone ID Related Accession (Same CDS sequence)	XM_017017145.1
Accession Version	XM_017017145.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2622bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	A disintegrin and metalloproteinase with thrombospondin motifs 8 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000011.10) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGCTCCCCG CCCCCGCCGC CCCCCGGTGG CCTCCGCTCC TGCTGCTGCT GCTGCTGCTG 
CTGCCGCTGG CCCGCGGCGC CCCGGCCCGG CCCGCAGCCG GGGGGCAGGC CTCGGAGCTG 
GTGGTGCCCA CGCGGTTGCC CGGCAGCGCG GGCGAGCTCG CGCTCCACCT GTCCGCCTTC 
GGCAAGGGCT TCGTGCTGCG CCTGGCGCCC GACGACAGCT TCCTAGCGCC CGAGTTCAAG 
ATCGAGCGCC TCGGGGGCTC CGGCCGGGCG ACCGGGGGCG AGCGGGGGCT GCGCGGCTGC 
TTCTTCTCCG GCACCGTGAA TGGGGAGCCC GAGTCGCTGG CGGCGGTCAG CCTGTGCCGC 
GGGCTGAGCG GCTCCTTCCT GCTGGACGGC GAGGAGTTCA CCATCCAGCC GCAGGGCGCG 
GGGGGCTCCC TGGCTCAGCC GCACCGCCTG CAGCGCTGGG GTCCCGCCGG AGCCCGCCCC 
CTCCCGCGAG GACCCGAGTG GGAGGTGGAG ACGGGAGAGG GTCAGAGGCA GGAGAGAGGA 
GACCACCAGG AGGACAGCGA GGAGGAGAGC CAAGAAGAGG AGGCAGAAGG CGCTAGCGAG 
CCGCCACCGC CCCTGGGGGC CACGAGTAGG ACCAAGCGGT TTGTGTCTGA GGCGCGCTTC 
GTGGAGACGC TGCTGGTGGC CGATGCGTCC ATGGCTGCCT TCTACGGGGC CGACCTGCAG 
AACCACATCC TGACGTTAAT GTCTGTGGCA GCCCGAATCT ACAAGCACCC CAGCATCAAG 
AATTCCATCA ACCTGATGGT GGTAAAAGTG CTGATCGTAG AAGATGAAAA ATGGGGCCCA 
GAGGTGTCCG ACAATGGGGG GCTTACACTG CGTAACTTCT GCAACTGGCA GCGGCGTTTC 
AACCAGCCCA GCGACCGCCA CCCAGAGCAC TACGACACGG CCATCCTGCT CACCAGACAG 
AACTTCTGTG GGCAGGAGGG GCTGTGTGAC ACCCTGGGTG TGGCAGACAT CGGGACCATT 
TGTGACCCCA ACAAAAGCTG CTCCGTGATC GAGGATGAGG GGCTCCAGGC GGCCCACACC 
CTGGCCCATG AACTAGGGCA CGTCCTCAGC ATGCCCCACG ACGACTCCAA GCCCTGCACA 
CGGCTCTTCG GGCCCATGGG CAAGCACCAC GTGATGGCAC CGCTGTTCGT CCACCTGAAC 
CAGACGCTGC CCTGGTCCCC CTGCAGCGCC ATGTATCTCA CAGAGCTTCT GGACGGCGGG 
CACGGCCTCC CGGGCCGCAT GGCCCTGTAC CAGCTGGACC AGCAGTGCAG GCAGATCTTT 
GGGCCGGATT TCCGCCACTG CCCCAACACC TCTGCTCAGG ACGTCTGCGC CCAGCTTTGG 
TGCCACACTG ATGGGGCTGA GCCCCTGTGC CACACGAAGA ATGGCAGCCT GCCCTGGGCT 
GACGGCACGC CGTGCGGGCC TGGGCACCTC TGCTCAGAAG GCAGCTGTCT ACCTGAGGAG 
GAAGTGGAGA GGCCCAAGCC CGTGGCAGAT GGAGGCTGGG CACCGTGGGG ACCCTGGGGA 
GAATGTTCTC GGACCTGTGG AGGAGGAGTA CAGTTTTCAC ACCGTGAGTG CAAGGACCCC 
GAGCCTCAGA ATGGAGGAAG ATACTGCCTG GGTCGGAGAG CCAAGTACCA GTCATGCCAC 
ACGGAGGAAT GCCCCCCTGA CGGGAAAAGC TTCAGGGAGC AGCAGTGTGA GAAGTATAAT 
GCCTACAATT ACACTGACAT GGACGGGAAT CTCCTGCAGT GGGTCCCCAA GTATGCTGGG 
GTGTCCCCCC GGGACCGCTG CAAGTTGTTC TGCCGAGCCC GGGGGAGGAG CGAGTTCAAA 
GTGTTCGAGG CCAAGGTGAT TGATGGCACC CTGTGTGGGC CAGAAACACT GGCCATCTGT 
GTCCGTGGCC AGTGTGTCAA GGCCGGCTGT GACCATGTGG TGGACTCGCC TCGGAAGCTG 
GACAAATGCG GGGTGTGTGG GGGCAAAGGC AACTCCTGCA GGAAGGTCTC CGGGTCCCTC 
ACCCCCACCA ATTATGGCTA CAATGACATT GTCACCATCC CAGCTGGTGC CACTAATATT 
GACGTGAAGC AGCGGAGCCA CCCGGGTGTG CAGAACGATG GGAACTACCT GGCGCTGAAG 
ACGGCTGATG GGCAGTACCT GCTCAACGGC AACCTGGCCA TCTCTGCCAT AGAGCAGGAC 
ATCTTGGTGA AGGGGACCAT CCTGAAGTAC AGCGGCTCCA TCGCCACCCT GGAGCGCCTG 
CAGAGCTTCC GGCCCTTGCC AGAGCCTCTG ACAGTGCAGC TCCTGACAGT CCCTGGCGAG 
GTCTTCCCCC CAAAAGTCAA ATACACCTTC TTTGTTCCTA ATGACGTGGA CTTTAGCATG 
CAGAGCAGCA AAGAGAGAGC AACCACCAAC ATCATCCAGC CGCTGCTCCA CGCACAGTGG 
GTGCTGGGGG ACTGGTCTGA GTGCTCTAGC ACCTGCGGGG CCGGCTGGCA GAGGCGAACT 
GTAGAGTGCA GGGACCCCTC CGGCCAGGCC TCTGCCACCT GCAACAAGGC TCTGAAACCC 
GAGGATGCCA AGCCCTGCGA AAGCCAGCTG TGCCCCCTGT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_016872634.1
CDS	228..2849
Translation	MLPAPAAPRWPPLLLLLLLLLPLARGAPARPAAGGQASELVVPTRLPGSAGELALHLSAFGKGFVLRLAPDDSFLAPEFKIERLGGSGRATGGERGLRGCFFSGTVNGEPESLAAVSLCRGLSGSFLLDGEEFTIQPQGAGGSLAQPHRLQRWGPAGARPLPRGPEWEVETGEGQRQERGDHQEDSEEESQEEEAEGASEPPPPLGATSRTKRFVSEARFVETLLVADASMAAFYGADLQNHILTLMSVAARIYKHPSIKNSINLMVVKVLIVEDEKWGPEVSDNGGLTLRNFCNWQRRFNQPSDRHPEHYDTAILLTRQNFCGQEGLCDTLGVADIGTICDPNKSCSVIEDEGLQAAHTLAHELGHVLSMPHDDSKPCTRLFGPMGKHHVMAPLFVHLNQTLPWSPCSAMYLTELLDGGHGLPGRMALYQLDQQCRQIFGPDFRHCPNTSAQDVCAQLWCHTDGAEPLCHTKNGSLPWADGTPCGPGHLCSEGSCLPEEEVERPKPVADGGWAPWGPWGECSRTCGGGVQFSHRECKDPEPQNGGRYCLGRRAKYQSCHTEECPPDGKSFREQQCEKYNAYNYTDMDGNLLQWVPKYAGVSPRDRCKLFCRARGRSEFKVFEAKVIDGTLCGPETLAICVRGQCVKAGCDHVVDSPRKLDKCGVCGGKGNSCRKVSGSLTPTNYGYNDIVTIPAGATNIDVKQRSHPGVQNDGNYLALKTADGQYLLNGNLAISAIEQDILVKGTILKYSGSIATLERLQSFRPLPEPLTVQLLTVPGEVFPPKVKYTFFVPNDVDFSMQSSKERATTNIIQPLLHAQWVLGDWSECSSTCGAGWQRRTVECRDPSGQASATCNKALKPEDAKPCESQLCPL

Target ORF information:

RefSeq Version	XM_017017145.1
Organism	Homo sapiens(human)
Definition	Homo sapiens ADAM metallopeptidase with thrombospondin type 1 motif 8 (ADAMTS8), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017017145.1

ORF Insert Sequence:

ATGCTCCCCG CCCCCGCCGC CCCCCGGTGG CCTCCGCTCC TGCTGCTGCT GCTGCTGCTG 
CTGCCGCTGG CCCGCGGCGC CCCGGCCCGG CCCGCAGCCG GGGGGCAGGC CTCGGAGCTG 
GTGGTGCCCA CGCGGTTGCC CGGCAGCGCG GGCGAGCTCG CGCTCCACCT GTCCGCCTTC 
GGCAAGGGCT TCGTGCTGCG CCTGGCGCCC GACGACAGCT TCCTAGCGCC CGAGTTCAAG 
ATCGAGCGCC TCGGGGGCTC CGGCCGGGCG ACCGGGGGCG AGCGGGGGCT GCGCGGCTGC 
TTCTTCTCCG GCACCGTGAA TGGGGAGCCC GAGTCGCTGG CGGCGGTCAG CCTGTGCCGC 
GGGCTGAGCG GCTCCTTCCT GCTGGACGGC GAGGAGTTCA CCATCCAGCC GCAGGGCGCG 
GGGGGCTCCC TGGCTCAGCC GCACCGCCTG CAGCGCTGGG GTCCCGCCGG AGCCCGCCCC 
CTCCCGCGAG GACCCGAGTG GGAGGTGGAG ACGGGAGAGG GTCAGAGGCA GGAGAGAGGA 
GACCACCAGG AGGACAGCGA GGAGGAGAGC CAAGAAGAGG AGGCAGAAGG CGCTAGCGAG 
CCGCCACCGC CCCTGGGGGC CACGAGTAGG ACCAAGCGGT TTGTGTCTGA GGCGCGCTTC 
GTGGAGACGC TGCTGGTGGC CGATGCGTCC ATGGCTGCCT TCTACGGGGC CGACCTGCAG 
AACCACATCC TGACGTTAAT GTCTGTGGCA GCCCGAATCT ACAAGCACCC CAGCATCAAG 
AATTCCATCA ACCTGATGGT GGTAAAAGTG CTGATCGTAG AAGATGAAAA ATGGGGCCCA 
GAGGTGTCCG ACAATGGGGG GCTTACACTG CGTAACTTCT GCAACTGGCA GCGGCGTTTC 
AACCAGCCCA GCGACCGCCA CCCAGAGCAC TACGACACGG CCATCCTGCT CACCAGACAG 
AACTTCTGTG GGCAGGAGGG GCTGTGTGAC ACCCTGGGTG TGGCAGACAT CGGGACCATT 
TGTGACCCCA ACAAAAGCTG CTCCGTGATC GAGGATGAGG GGCTCCAGGC GGCCCACACC 
CTGGCCCATG AACTAGGGCA CGTCCTCAGC ATGCCCCACG ACGACTCCAA GCCCTGCACA 
CGGCTCTTCG GGCCCATGGG CAAGCACCAC GTGATGGCAC CGCTGTTCGT CCACCTGAAC 
CAGACGCTGC CCTGGTCCCC CTGCAGCGCC ATGTATCTCA CAGAGCTTCT GGACGGCGGG 
CACGGCCTCC CGGGCCGCAT GGCCCTGTAC CAGCTGGACC AGCAGTGCAG GCAGATCTTT 
GGGCCGGATT TCCGCCACTG CCCCAACACC TCTGCTCAGG ACGTCTGCGC CCAGCTTTGG 
TGCCACACTG ATGGGGCTGA GCCCCTGTGC CACACGAAGA ATGGCAGCCT GCCCTGGGCT 
GACGGCACGC CGTGCGGGCC TGGGCACCTC TGCTCAGAAG GCAGCTGTCT ACCTGAGGAG 
GAAGTGGAGA GGCCCAAGCC CGTGGCAGAT GGAGGCTGGG CACCGTGGGG ACCCTGGGGA 
GAATGTTCTC GGACCTGTGG AGGAGGAGTA CAGTTTTCAC ACCGTGAGTG CAAGGACCCC 
GAGCCTCAGA ATGGAGGAAG ATACTGCCTG GGTCGGAGAG CCAAGTACCA GTCATGCCAC 
ACGGAGGAAT GCCCCCCTGA CGGGAAAAGC TTCAGGGAGC AGCAGTGTGA GAAGTATAAT 
GCCTACAATT ACACTGACAT GGACGGGAAT CTCCTGCAGT GGGTCCCCAA GTATGCTGGG 
GTGTCCCCCC GGGACCGCTG CAAGTTGTTC TGCCGAGCCC GGGGGAGGAG CGAGTTCAAA 
GTGTTCGAGG CCAAGGTGAT TGATGGCACC CTGTGTGGGC CAGAAACACT GGCCATCTGT 
GTCCGTGGCC AGTGTGTCAA GGCCGGCTGT GACCATGTGG TGGACTCGCC TCGGAAGCTG 
GACAAATGCG GGGTGTGTGG GGGCAAAGGC AACTCCTGCA GGAAGGTCTC CGGGTCCCTC 
ACCCCCACCA ATTATGGCTA CAATGACATT GTCACCATCC CAGCTGGTGC CACTAATATT 
GACGTGAAGC AGCGGAGCCA CCCGGGTGTG CAGAACGATG GGAACTACCT GGCGCTGAAG 
ACGGCTGATG GGCAGTACCT GCTCAACGGC AACCTGGCCA TCTCTGCCAT AGAGCAGGAC 
ATCTTGGTGA AGGGGACCAT CCTGAAGTAC AGCGGCTCCA TCGCCACCCT GGAGCGCCTG 
CAGAGCTTCC GGCCCTTGCC AGAGCCTCTG ACAGTGCAGC TCCTGACAGT CCCTGGCGAG 
GTCTTCCCCC CAAAAGTCAA ATACACCTTC TTTGTTCCTA ATGACGTGGA CTTTAGCATG 
CAGAGCAGCA AAGAGAGAGC AACCACCAAC ATCATCCAGC CGCTGCTCCA CGCACAGTGG 
GTGCTGGGGG ACTGGTCTGA GTGCTCTAGC ACCTGCGGGG CCGGCTGGCA GAGGCGAACT 
GTAGAGTGCA GGGACCCCTC CGGCCAGGCC TCTGCCACCT GCAACAAGGC TCTGAAACCC 
GAGGATGCCA AGCCCTGCGA AAGCCAGCTG TGCCCCCTGT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Differentially regulated ADAMTS1, 8, and 18 in gastric adenocarcinoma.
Bratislavske lekarske listy118(2)71-76(2017)
Kilic MO,Aynekin B,Kara A,Icen D,Demircan K

Downregulation of ADAMTS8 by DNA Hypermethylation in Gastric Cancer and Its Clinical Significance.
BioMed research international20165083841(2016)
Chen J,Zhang J,Li X,Zhang C,Zhang H,Jin J,Dai D

Meta-analysis of genome-wide association studies identifies novel loci that influence cupping and the glaucomatous process.
Nature communications54883(2014 Sep)
Springelkamp H,H?hn R,Mishra A,Hysi PG,Khor CC,Loomis SJ,Bailey JN,Gibson J,Thorleifsson G,Janssen SF,Luo X,Ramdas WD,Vithana E,Nongpiur ME,Montgomery GW,Xu L,Mountain JE,Gharahkhani P,Lu Y,Amin N,Karssen LC,Sim KS,van Leeuwen EM,Iglesias AI,Verhoeven VJ,Hauser MA,Loon SC,Despriet DD,Nag A,Venturini C,Sanfilippo PG,Schillert A,Kang JH,Landers J,Jonasson F,Cree AJ,van Koolwijk LM,Rivadeneira F,Souzeau E,Jonsson V,Menon G,,Weinreb RN,de Jong PT,Oostra BA,Uitterlinden AG,Hofman A,Ennis S,Thorsteinsdottir U,Burdon KP,,,Spector TD,Mirshahi A,Saw SM,Vingerling JR,Teo YY,Haines JL,Wolfs RC,Lemij HG,Tai ES,Jansonius NM,Jonas JB,Cheng CY,Aung T,Viswanathan AC,Klaver CC,Craig JE,Macgregor S,Mackey DA,Lotery AJ,Stefansson K,Bergen AA,Young TL,Wiggs JL,Pfeiffer N,Wong TY,Pasquale LR,Hewitt AW,van Duijn CM,Hammond CJ

Genome-wide study reveals an important role of spontaneous autoimmunity, cardiomyocyte differentiation defect and anti-angiogenic activities in gender-specific gene expression in Keshan disease.
Chinese medical journal127(1)72-8(2014)
He S,Tan W,Wang S,Wu C,Wang P,Wang B,Su X,Zhao J,Guo X,Xiang Y

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ADAMTS8 cDNA ORF clone, Homo sapiens(Human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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