CNMD cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	CNMD
Entrez Gene ID	11061
Full Name	chondromodulin
Synonyms	BRICD3,CHM-I,CHM1,LECT1,MYETS1
General protein information	Preferred Names chondromodulin Names leukocyte cell-derived chemotaxin 1 BRICHOS domain containing 3 chondromodulin-1 chondromodulin-I leukocyte cell derived chemotaxin 1 multiple myeloma tumor suppressor 1
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 13 Map Location: 13q14.3
Summary	This gene encodes a glycosylated transmembrane protein that is cleaved to form a mature, secreted protein. The N-terminus of the precursor protein shares characteristics with other surfactant proteins and is sometimes called chondrosurfactant protein although no biological activity has yet been defined for it. The C-terminus of the precursor protein contains a 25 kDa mature protein called leukocyte cell-derived chemotaxin-1 or chondromodulin-1. The mature protein promotes chondrocyte growth and inhibits angiogenesis. This gene is expressed in the avascular zone of prehypertrophic cartilage and its expression decreases during chondrocyte hypertrophy and vascular invasion. The mature protein likely plays a role in endochondral bone development by permitting cartilaginous anlagen to be vascularized and replaced by bone. It may be involved also in the broad control of tissue vascularization during development. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008].
Disorder MIM:	605147

mRNA and Protein(s)

mRNA	Protein	Name
XM_011534898.2	XP_011533200.1	leukocyte cell-derived chemotaxin 1 isoform X2
NM_001011705.2	NP_001011705.1	leukocyte cell-derived chemotaxin 1 isoform 2 precursor
NM_001011705.1	NP_001011705.1	leukocyte cell-derived chemotaxin 1 isoform 2 precursor
XM_011534899.2	XP_011533201.1	leukocyte cell-derived chemotaxin 1 isoform X3
XM_011534900.2	XP_011533202.1	leukocyte cell-derived chemotaxin 1 isoform X4
NM_007015.2	NP_008946.1	leukocyte cell-derived chemotaxin 1 isoform 1 precursor
NM_007015.3	NP_008946.1	leukocyte cell-derived chemotaxin 1 isoform 1 precursor
XM_011534897.2	XP_011533199.1	leukocyte cell-derived chemotaxin 1 isoform X1

Pathways from BioSystems

Homologies

Xenopus tropicalis (tropical clawed frog)	lect1	NP_001090798.1
Pan troglodytes (chimpanzee)	LECT1	XP_001136784.2
	LECT1	XP_001084639.2
Bos taurus (cattle)	LECT1	NP_776694.1
Gallus gallus (chicken)	LECT1	NP_990141.1
Canis lupus familiaris (dog)	LECT1	XP_851994.1
Mus musculus (house mouse)	Lect1	NP_034831.2
Rattus norvegicus (Norway rat)	Lect1	NP_110481.1
Homo sapiens (human)	LECT1	NP_008946.1
Danio rerio (zebrafish)	lect1	NP_001119920.1

Gene Ontology
Bibliography

Related articles in PubMed

Chondromodulin?I suppresses tumorigenesis of human osteosarcoma cells.
Lin X, Wang L, Wang F
Molecular medicine reports16(6)8542-8548(2017 Dec)

The endochondral bone protein CHM1 sustains an undifferentiated, invasive phenotype, promoting lung metastasis in Ewing sarcoma.
von Heyking K, Calzada-Wack J, G?llner S, Neff F, Schmidt O, Hensel T, Schirmer D, Fasan A, Esposito I, M?ller-Tidow C, Sorensen PH, Burdach S, Richter GHS
Molecular oncology11(9)1288-1301(2017 Sep)

Transfection of chondromodulin I into human breast cancer cells and its effect on the inhibition of cancer cell growth.
Shao J, Gan L, Wang J
Molecular medicine reports13(5)4303-8(2016 May)

Chondromodulin-1 functions as a tumor suppressor in gastric adenocarcinoma.
Zhang P, Wang Y, Xu P, Song S, Zhu X, Shi Z, Gao S, Feng X
International journal of oncology47(3)941-50(2015 Sep)

The N-terminal cleavage of chondromodulin-I in growth-plate cartilage at the hypertrophic and calcified zones during bone development.
Miura S, Kondo J, Takimoto A, Sano-Takai H, Guo L, Shukunami C, Tanaka H, Hiraki Y
PloS one9(4)e94239(2014)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The results of the present study indicated that ChMI was able to inhibit the growth of breast cancer cells; thus suggesting that ChM-I may have potential clinical applications in the treatment of breast cancer.
Title: Transfection of chondromodulin I into human breast cancer cells and its effect on the inhibition of cancer cell growth.

Data suggest ChM1 as potential tumor suppressor in gastric cancer and useful biomarker for the treatment and prognosis. Its expression was downregulated in cancer tissue, and correlated with advanced stages, lymph node metastasis, and poorer prognosis.
Title: Chondromodulin-1 functions as a tumor suppressor in gastric adenocarcinoma.

intact 20-25 kDa ChM-I is stored as a component of extracellular matrix in the avascular cartilage zones, but it is inactivated by a single N-terminal proteolytic cleavage in the hypertrophic zone of growth-plate cartilage
Title: The N-terminal cleavage of chondromodulin-I in growth-plate cartilage at the hypertrophic and calcified zones during bone development.

the inner meniscus contained larger amounts of ChM-I, and that the inner meniscus-derived ChM-I inhibited endothelial cell proliferation.
Title: Chondromodulin-I derived from the inner meniscus prevents endothelial cell proliferation.

Degenerative intervertebral disc cells express ChM-I. Administration of bFGF down-regulates the expression of ChM-I. Expression is correlated with the degree of degeneration.
Title: [Expression of chondromodulin-1 in the adult degenerative intervertebral disc].

The following CNMD gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the CNMD cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu13160	NM_007015.3 Latest version!	Homo sapiens chondromodulin (CNMD), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$223.30 $319.00
OHu13220	NM_001011705.2 Latest version!	Homo sapiens chondromodulin (CNMD), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$265.30 $379.00
OHu64665	XM_011534897.2 Latest version!	Homo sapiens chondromodulin (CNMD), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$223.30 $319.00
OHu64666	XM_011534898.2 Latest version!	Homo sapiens chondromodulin (CNMD), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$223.30 $319.00
OHu64667	XM_011534899.2 Latest version!	Homo sapiens chondromodulin (CNMD), transcript variant X3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$139.30 $199.00
OHu64668	XM_011534900.2 Latest version!	Homo sapiens chondromodulin (CNMD), transcript variant X4, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$139.30 $199.00
View Old Accession Versions >>
OHu13220	NM_001011705.1	Homo sapiens chondromodulin (CNMD), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$265.30 $379.00
OHu13160	NM_007015.2	Homo sapiens chondromodulin (CNMD), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$223.30 $319.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

CNMD ( NM_007015.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_008946.1 Homo sapiens chondromodulin (CNMD), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu13160
Clone ID Related Accession (Same CDS sequence)	NM_007015.2 , NM_007015.3
Accession Version	NM_007015.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1005bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-09-30
Organism	Homo sapiens(human)
Product	leukocyte cell-derived chemotaxin 1 isoform 1 precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BC025659.1 and CR541910.1. On Feb 15, 2005 this sequence version replaced NM_007015.1. Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AB006000.1, CR541910.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968832, SAMEA1968968 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## CDS uses downstream in-frame AUG :: lack of evidence for use of upstream AUG ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGACAGAGA ACTCCGACAA AGTTCCCATT GCCCTGGTGG GACCTGATGA CGTGGAATTC 
TGCAGCCCCC CGGCGTACGC TACGCTGACG GTGAAGCCCT CCAGCCCCGC GCGGCTGCTC 
AAGGTGGGAG CCGTGGTCCT CATTTCGGGA GCTGTGCTGC TGCTCTTTGG GGCCATCGGG 
GCCTTCTACT TCTGGAAGGG GAGCGACAGT CACATTTACA ATGTCCATTA CACCATGAGT 
ATCAATGGGA AATTACAAGA TGGGTCAATG GAAATAGACG CTGGGAACAA CTTGGAGACC 
TTTAAAATGG GAAGTGGAGC TGAAGAAGCA ATTGCAGTTA ATGATTTCCA GAATGGCATC 
ACAGGAATTC GTTTTGCTGG AGGAGAGAAG TGCTACATTA AAGCGCAAGT GAAGGCTCGT 
ATTCCTGAGG TGGGCGCCGT GACCAAACAG AGCATCTCCT CCAAACTGGA AGGCAAGATC 
ATGCCAGTCA AATATGAAGA AAATTCTCTT ATCTGGGTGG CTGTAGATCA GCCTGTGAAG 
GACAACAGCT TCTTGAGTTC TAAGGTGTTA GAACTCTGCG GTGACCTTCC TATTTTCTGG 
CTTAAACCAA CCTATCCAAA AGAAATCCAG AGGGAAAGAA GAGAAGTGGT AAGAAAAATT 
GTTCCAACTA CCACAAAAAG ACCACACAGT GGACCACGGA GCAACCCAGG CGCTGGAAGA 
CTGAATAATG AAACCAGACC CAGTGTTCAA GAGGACTCAC AAGCCTTCAA TCCTGATAAT 
CCTTATCATC AGCAGGAAGG GGAAAGCATG ACATTCGACC CTAGACTGGA TCACGAAGGA 
ATCTGTTGTA TAGAATGTAG GCGGAGCTAC ACCCACTGCC AGAAGATCTG TGAACCCCTG 
GGGGGCTATT ACCCATGGCC TTATAATTAT CAAGGCTGCC GTTCGGCCTG CAGAGTCATC 
ATGCCATGTA GCTGGTGGGT GGCCCGTATC TTGGGCATGG TGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_008946.1
CDS	112..1116
Translation	MTENSDKVPIALVGPDDVEFCSPPAYATLTVKPSSPARLLKVGAVVLISGAVLLLFGAIGAFYFWKGSDSHIYNVHYTMSINGKLQDGSMEIDAGNNLETFKMGSGAEEAIAVNDFQNGITGIRFAGGEKCYIKAQVKARIPEVGAVTKQSISSKLEGKIMPVKYEENSLIWVAVDQPVKDNSFLSSKVLELCGDLPIFWLKPTYPKEIQRERREVVRKIVPTTTKRPHSGPRSNPGAGRLNNETRPSVQEDSQAFNPDNPYHQQEGESMTFDPRLDHEGICCIECRRSYTHCQKICEPLGGYYPWPYNYQGCRSACRVIMPCSWWVARILGMV

Target ORF information:

RefSeq Version	NM_007015.2
Organism	Homo sapiens(human)
Definition	Homo sapiens chondromodulin (CNMD), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_007015.2

ORF Insert Sequence:

ATGACAGAGA ACTCCGACAA AGTTCCCATT GCCCTGGTGG GACCTGATGA CGTGGAATTC 
TGCAGCCCCC CGGCGTACGC TACGCTGACG GTGAAGCCCT CCAGCCCCGC GCGGCTGCTC 
AAGGTGGGAG CCGTGGTCCT CATTTCGGGA GCTGTGCTGC TGCTCTTTGG GGCCATCGGG 
GCCTTCTACT TCTGGAAGGG GAGCGACAGT CACATTTACA ATGTCCATTA CACCATGAGT 
ATCAATGGGA AATTACAAGA TGGGTCAATG GAAATAGACG CTGGGAACAA CTTGGAGACC 
TTTAAAATGG GAAGTGGAGC TGAAGAAGCA ATTGCAGTTA ATGATTTCCA GAATGGCATC 
ACAGGAATTC GTTTTGCTGG AGGAGAGAAG TGCTACATTA AAGCGCAAGT GAAGGCTCGT 
ATTCCTGAGG TGGGCGCCGT GACCAAACAG AGCATCTCCT CCAAACTGGA AGGCAAGATC 
ATGCCAGTCA AATATGAAGA AAATTCTCTT ATCTGGGTGG CTGTAGATCA GCCTGTGAAG 
GACAACAGCT TCTTGAGTTC TAAGGTGTTA GAACTCTGCG GTGACCTTCC TATTTTCTGG 
CTTAAACCAA CCTATCCAAA AGAAATCCAG AGGGAAAGAA GAGAAGTGGT AAGAAAAATT 
GTTCCAACTA CCACAAAAAG ACCACACAGT GGACCACGGA GCAACCCAGG CGCTGGAAGA 
CTGAATAATG AAACCAGACC CAGTGTTCAA GAGGACTCAC AAGCCTTCAA TCCTGATAAT 
CCTTATCATC AGCAGGAAGG GGAAAGCATG ACATTCGACC CTAGACTGGA TCACGAAGGA 
ATCTGTTGTA TAGAATGTAG GCGGAGCTAC ACCCACTGCC AGAAGATCTG TGAACCCCTG 
GGGGGCTATT ACCCATGGCC TTATAATTAT CAAGGCTGCC GTTCGGCCTG CAGAGTCATC 
ATGCCATGTA GCTGGTGGGT GGCCCGTATC TTGGGCATGG TGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

CNMD ( NM_007015.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_008946.1 Homo sapiens chondromodulin (CNMD), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu13160
Clone ID Related Accession (Same CDS sequence)	NM_007015.2 , NM_007015.3
Accession Version	NM_007015.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1005bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-09-26
Organism	Homo sapiens(human)
Product	leukocyte cell-derived chemotaxin 1 isoform 1 precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AL139085.13 and AL139089.13. On Nov 23, 2018 this sequence version replaced NM_007015.2. Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR3476690.542565.1, AB006000.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968832, SAMEA1968968 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## CDS uses downstream in-frame AUG :: lack of evidence for use of upstream AUG MANE Ensembl match :: ENST00000377962.8/ ENSP00000367198.3 RefSeq Select criteria :: based on conservation, expression ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGACAGAGA ACTCCGACAA AGTTCCCATT GCCCTGGTGG GACCTGATGA CGTGGAATTC 
TGCAGCCCCC CGGCGTACGC TACGCTGACG GTGAAGCCCT CCAGCCCCGC GCGGCTGCTC 
AAGGTGGGAG CCGTGGTCCT CATTTCGGGA GCTGTGCTGC TGCTCTTTGG GGCCATCGGG 
GCCTTCTACT TCTGGAAGGG GAGCGACAGT CACATTTACA ATGTCCATTA CACCATGAGT 
ATCAATGGGA AATTACAAGA TGGGTCAATG GAAATAGACG CTGGGAACAA CTTGGAGACC 
TTTAAAATGG GAAGTGGAGC TGAAGAAGCA ATTGCAGTTA ATGATTTCCA GAATGGCATC 
ACAGGAATTC GTTTTGCTGG AGGAGAGAAG TGCTACATTA AAGCGCAAGT GAAGGCTCGT 
ATTCCTGAGG TGGGCGCCGT GACCAAACAG AGCATCTCCT CCAAACTGGA AGGCAAGATC 
ATGCCAGTCA AATATGAAGA AAATTCTCTT ATCTGGGTGG CTGTAGATCA GCCTGTGAAG 
GACAACAGCT TCTTGAGTTC TAAGGTGTTA GAACTCTGCG GTGACCTTCC TATTTTCTGG 
CTTAAACCAA CCTATCCAAA AGAAATCCAG AGGGAAAGAA GAGAAGTGGT AAGAAAAATT 
GTTCCAACTA CCACAAAAAG ACCACACAGT GGACCACGGA GCAACCCAGG CGCTGGAAGA 
CTGAATAATG AAACCAGACC CAGTGTTCAA GAGGACTCAC AAGCCTTCAA TCCTGATAAT 
CCTTATCATC AGCAGGAAGG GGAAAGCATG ACATTCGACC CTAGACTGGA TCACGAAGGA 
ATCTGTTGTA TAGAATGTAG GCGGAGCTAC ACCCACTGCC AGAAGATCTG TGAACCCCTG 
GGGGGCTATT ACCCATGGCC TTATAATTAT CAAGGCTGCC GTTCGGCCTG CAGAGTCATC 
ATGCCATGTA GCTGGTGGGT GGCCCGTATC TTGGGCATGG TGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_008946.1
CDS	120..1124
Translation	MTENSDKVPIALVGPDDVEFCSPPAYATLTVKPSSPARLLKVGAVVLISGAVLLLFGAIGAFYFWKGSDSHIYNVHYTMSINGKLQDGSMEIDAGNNLETFKMGSGAEEAIAVNDFQNGITGIRFAGGEKCYIKAQVKARIPEVGAVTKQSISSKLEGKIMPVKYEENSLIWVAVDQPVKDNSFLSSKVLELCGDLPIFWLKPTYPKEIQRERREVVRKIVPTTTKRPHSGPRSNPGAGRLNNETRPSVQEDSQAFNPDNPYHQQEGESMTFDPRLDHEGICCIECRRSYTHCQKICEPLGGYYPWPYNYQGCRSACRVIMPCSWWVARILGMV

Target ORF information:

RefSeq Version	NM_007015.3
Organism	Homo sapiens(human)
Definition	Homo sapiens chondromodulin (CNMD), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_007015.3

ORF Insert Sequence:

ATGACAGAGA ACTCCGACAA AGTTCCCATT GCCCTGGTGG GACCTGATGA CGTGGAATTC 
TGCAGCCCCC CGGCGTACGC TACGCTGACG GTGAAGCCCT CCAGCCCCGC GCGGCTGCTC 
AAGGTGGGAG CCGTGGTCCT CATTTCGGGA GCTGTGCTGC TGCTCTTTGG GGCCATCGGG 
GCCTTCTACT TCTGGAAGGG GAGCGACAGT CACATTTACA ATGTCCATTA CACCATGAGT 
ATCAATGGGA AATTACAAGA TGGGTCAATG GAAATAGACG CTGGGAACAA CTTGGAGACC 
TTTAAAATGG GAAGTGGAGC TGAAGAAGCA ATTGCAGTTA ATGATTTCCA GAATGGCATC 
ACAGGAATTC GTTTTGCTGG AGGAGAGAAG TGCTACATTA AAGCGCAAGT GAAGGCTCGT 
ATTCCTGAGG TGGGCGCCGT GACCAAACAG AGCATCTCCT CCAAACTGGA AGGCAAGATC 
ATGCCAGTCA AATATGAAGA AAATTCTCTT ATCTGGGTGG CTGTAGATCA GCCTGTGAAG 
GACAACAGCT TCTTGAGTTC TAAGGTGTTA GAACTCTGCG GTGACCTTCC TATTTTCTGG 
CTTAAACCAA CCTATCCAAA AGAAATCCAG AGGGAAAGAA GAGAAGTGGT AAGAAAAATT 
GTTCCAACTA CCACAAAAAG ACCACACAGT GGACCACGGA GCAACCCAGG CGCTGGAAGA 
CTGAATAATG AAACCAGACC CAGTGTTCAA GAGGACTCAC AAGCCTTCAA TCCTGATAAT 
CCTTATCATC AGCAGGAAGG GGAAAGCATG ACATTCGACC CTAGACTGGA TCACGAAGGA 
ATCTGTTGTA TAGAATGTAG GCGGAGCTAC ACCCACTGCC AGAAGATCTG TGAACCCCTG 
GGGGGCTATT ACCCATGGCC TTATAATTAT CAAGGCTGCC GTTCGGCCTG CAGAGTCATC 
ATGCCATGTA GCTGGTGGGT GGCCCGTATC TTGGGCATGG TGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

CNMD ( NM_001011705.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_001011705.1 Homo sapiens chondromodulin (CNMD), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu13220
Clone ID Related Accession (Same CDS sequence)	NM_001011705.2 , NM_001011705.1
Accession Version	NM_001011705.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1002bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-09-27
Organism	Homo sapiens(human)
Product	leukocyte cell-derived chemotaxin 1 isoform 2 precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AL139085.13 and AL139089.13. On May 31, 2019 this sequence version replaced NM_001011705.1. Transcript Variant: This variant (2) uses an alternate in-frame splice site in the 3' coding region, compared to variant 1, resulting in a shorter protein (isoform 2). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC025659.1, DN601642.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968968, SAMEA2144120 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## CDS uses downstream in-frame AUG :: lack of evidence for use of upstream AUG ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGACAGAGA ACTCCGACAA AGTTCCCATT GCCCTGGTGG GACCTGATGA CGTGGAATTC 
TGCAGCCCCC CGGCGTACGC TACGCTGACG GTGAAGCCCT CCAGCCCCGC GCGGCTGCTC 
AAGGTGGGAG CCGTGGTCCT CATTTCGGGA GCTGTGCTGC TGCTCTTTGG GGCCATCGGG 
GCCTTCTACT TCTGGAAGGG GAGCGACAGT CACATTTACA ATGTCCATTA CACCATGAGT 
ATCAATGGGA AATTACAAGA TGGGTCAATG GAAATAGACG CTGGGAACAA CTTGGAGACC 
TTTAAAATGG GAAGTGGAGC TGAAGAAGCA ATTGCAGTTA ATGATTTCCA GAATGGCATC 
ACAGGAATTC GTTTTGCTGG AGGAGAGAAG TGCTACATTA AAGCGCAAGT GAAGGCTCGT 
ATTCCTGAGG TGGGCGCCGT GACCAAACAG AGCATCTCCT CCAAACTGGA AGGCAAGATC 
ATGCCAGTCA AATATGAAGA AAATTCTCTT ATCTGGGTGG CTGTAGATCA GCCTGTGAAG 
GACAACAGCT TCTTGAGTTC TAAGGTGTTA GAACTCTGCG GTGACCTTCC TATTTTCTGG 
CTTAAACCAA CCTATCCAAA AGAAATCCAG AGGGAAAGAA GAGAAGTGGT AAGAAAAATT 
GTTCCAACTA CCACAAAAAG ACCACACAGT GGACCACGGA GCAACCCAGG CGCTGGAAGA 
CTGAATAATG AAACCAGACC CAGTGTTCAA GAGGACTCAC AAGCCTTCAA TCCTGATAAT 
CCTTATCATC AGGAAGGGGA AAGCATGACA TTCGACCCTA GACTGGATCA CGAAGGAATC 
TGTTGTATAG AATGTAGGCG GAGCTACACC CACTGCCAGA AGATCTGTGA ACCCCTGGGG 
GGCTATTACC CATGGCCTTA TAATTATCAA GGCTGCCGTT CGGCCTGCAG AGTCATCATG 
CCATGTAGCT GGTGGGTGGC CCGTATCTTG GGCATGGTGT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001011705.1
CDS	120..1121
Translation	MTENSDKVPIALVGPDDVEFCSPPAYATLTVKPSSPARLLKVGAVVLISGAVLLLFGAIGAFYFWKGSDSHIYNVHYTMSINGKLQDGSMEIDAGNNLETFKMGSGAEEAIAVNDFQNGITGIRFAGGEKCYIKAQVKARIPEVGAVTKQSISSKLEGKIMPVKYEENSLIWVAVDQPVKDNSFLSSKVLELCGDLPIFWLKPTYPKEIQRERREVVRKIVPTTTKRPHSGPRSNPGAGRLNNETRPSVQEDSQAFNPDNPYHQEGESMTFDPRLDHEGICCIECRRSYTHCQKICEPLGGYYPWPYNYQGCRSACRVIMPCSWWVARILGMV

Target ORF information:

RefSeq Version	NM_001011705.2
Organism	Homo sapiens(human)
Definition	Homo sapiens chondromodulin (CNMD), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001011705.2

ORF Insert Sequence:

ATGACAGAGA ACTCCGACAA AGTTCCCATT GCCCTGGTGG GACCTGATGA CGTGGAATTC 
TGCAGCCCCC CGGCGTACGC TACGCTGACG GTGAAGCCCT CCAGCCCCGC GCGGCTGCTC 
AAGGTGGGAG CCGTGGTCCT CATTTCGGGA GCTGTGCTGC TGCTCTTTGG GGCCATCGGG 
GCCTTCTACT TCTGGAAGGG GAGCGACAGT CACATTTACA ATGTCCATTA CACCATGAGT 
ATCAATGGGA AATTACAAGA TGGGTCAATG GAAATAGACG CTGGGAACAA CTTGGAGACC 
TTTAAAATGG GAAGTGGAGC TGAAGAAGCA ATTGCAGTTA ATGATTTCCA GAATGGCATC 
ACAGGAATTC GTTTTGCTGG AGGAGAGAAG TGCTACATTA AAGCGCAAGT GAAGGCTCGT 
ATTCCTGAGG TGGGCGCCGT GACCAAACAG AGCATCTCCT CCAAACTGGA AGGCAAGATC 
ATGCCAGTCA AATATGAAGA AAATTCTCTT ATCTGGGTGG CTGTAGATCA GCCTGTGAAG 
GACAACAGCT TCTTGAGTTC TAAGGTGTTA GAACTCTGCG GTGACCTTCC TATTTTCTGG 
CTTAAACCAA CCTATCCAAA AGAAATCCAG AGGGAAAGAA GAGAAGTGGT AAGAAAAATT 
GTTCCAACTA CCACAAAAAG ACCACACAGT GGACCACGGA GCAACCCAGG CGCTGGAAGA 
CTGAATAATG AAACCAGACC CAGTGTTCAA GAGGACTCAC AAGCCTTCAA TCCTGATAAT 
CCTTATCATC AGGAAGGGGA AAGCATGACA TTCGACCCTA GACTGGATCA CGAAGGAATC 
TGTTGTATAG AATGTAGGCG GAGCTACACC CACTGCCAGA AGATCTGTGA ACCCCTGGGG 
GGCTATTACC CATGGCCTTA TAATTATCAA GGCTGCCGTT CGGCCTGCAG AGTCATCATG 
CCATGTAGCT GGTGGGTGGC CCGTATCTTG GGCATGGTGT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

CNMD ( NM_001011705.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001011705.1 Homo sapiens chondromodulin (CNMD), transcript variant 2, mRNA.

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CloneID	OHu13220
Clone ID Related Accession (Same CDS sequence)	NM_001011705.2 , NM_001011705.1
Accession Version	NM_001011705.1	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1002bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-02-16
Organism	Homo sapiens(human)
Product	leukocyte cell-derived chemotaxin 1 isoform 2 precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BC025659.1. Transcript Variant: This variant (2) uses an alternate in-frame splice site in the 3' coding region, compared to variant 1, resulting in a shorter protein (isoform 2). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC025659.1, DN601642.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968968, SAMEA2144120 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## CDS uses downstream in-frame AUG :: lack of evidence for use of upstream AUG ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGACAGAGA ACTCCGACAA AGTTCCCATT GCCCTGGTGG GACCTGATGA CGTGGAATTC 
TGCAGCCCCC CGGCGTACGC TACGCTGACG GTGAAGCCCT CCAGCCCCGC GCGGCTGCTC 
AAGGTGGGAG CCGTGGTCCT CATTTCGGGA GCTGTGCTGC TGCTCTTTGG GGCCATCGGG 
GCCTTCTACT TCTGGAAGGG GAGCGACAGT CACATTTACA ATGTCCATTA CACCATGAGT 
ATCAATGGGA AATTACAAGA TGGGTCAATG GAAATAGACG CTGGGAACAA CTTGGAGACC 
TTTAAAATGG GAAGTGGAGC TGAAGAAGCA ATTGCAGTTA ATGATTTCCA GAATGGCATC 
ACAGGAATTC GTTTTGCTGG AGGAGAGAAG TGCTACATTA AAGCGCAAGT GAAGGCTCGT 
ATTCCTGAGG TGGGCGCCGT GACCAAACAG AGCATCTCCT CCAAACTGGA AGGCAAGATC 
ATGCCAGTCA AATATGAAGA AAATTCTCTT ATCTGGGTGG CTGTAGATCA GCCTGTGAAG 
GACAACAGCT TCTTGAGTTC TAAGGTGTTA GAACTCTGCG GTGACCTTCC TATTTTCTGG 
CTTAAACCAA CCTATCCAAA AGAAATCCAG AGGGAAAGAA GAGAAGTGGT AAGAAAAATT 
GTTCCAACTA CCACAAAAAG ACCACACAGT GGACCACGGA GCAACCCAGG CGCTGGAAGA 
CTGAATAATG AAACCAGACC CAGTGTTCAA GAGGACTCAC AAGCCTTCAA TCCTGATAAT 
CCTTATCATC AGGAAGGGGA AAGCATGACA TTCGACCCTA GACTGGATCA CGAAGGAATC 
TGTTGTATAG AATGTAGGCG GAGCTACACC CACTGCCAGA AGATCTGTGA ACCCCTGGGG 
GGCTATTACC CATGGCCTTA TAATTATCAA GGCTGCCGTT CGGCCTGCAG AGTCATCATG 
CCATGTAGCT GGTGGGTGGC CCGTATCTTG GGCATGGTGT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001011705.1
CDS	112..1113
Translation	MTENSDKVPIALVGPDDVEFCSPPAYATLTVKPSSPARLLKVGAVVLISGAVLLLFGAIGAFYFWKGSDSHIYNVHYTMSINGKLQDGSMEIDAGNNLETFKMGSGAEEAIAVNDFQNGITGIRFAGGEKCYIKAQVKARIPEVGAVTKQSISSKLEGKIMPVKYEENSLIWVAVDQPVKDNSFLSSKVLELCGDLPIFWLKPTYPKEIQRERREVVRKIVPTTTKRPHSGPRSNPGAGRLNNETRPSVQEDSQAFNPDNPYHQEGESMTFDPRLDHEGICCIECRRSYTHCQKICEPLGGYYPWPYNYQGCRSACRVIMPCSWWVARILGMV

Target ORF information:

RefSeq Version	NM_001011705.1
Organism	Homo sapiens(human)
Definition	Homo sapiens chondromodulin (CNMD), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001011705.1

ORF Insert Sequence:

ATGACAGAGA ACTCCGACAA AGTTCCCATT GCCCTGGTGG GACCTGATGA CGTGGAATTC 
TGCAGCCCCC CGGCGTACGC TACGCTGACG GTGAAGCCCT CCAGCCCCGC GCGGCTGCTC 
AAGGTGGGAG CCGTGGTCCT CATTTCGGGA GCTGTGCTGC TGCTCTTTGG GGCCATCGGG 
GCCTTCTACT TCTGGAAGGG GAGCGACAGT CACATTTACA ATGTCCATTA CACCATGAGT 
ATCAATGGGA AATTACAAGA TGGGTCAATG GAAATAGACG CTGGGAACAA CTTGGAGACC 
TTTAAAATGG GAAGTGGAGC TGAAGAAGCA ATTGCAGTTA ATGATTTCCA GAATGGCATC 
ACAGGAATTC GTTTTGCTGG AGGAGAGAAG TGCTACATTA AAGCGCAAGT GAAGGCTCGT 
ATTCCTGAGG TGGGCGCCGT GACCAAACAG AGCATCTCCT CCAAACTGGA AGGCAAGATC 
ATGCCAGTCA AATATGAAGA AAATTCTCTT ATCTGGGTGG CTGTAGATCA GCCTGTGAAG 
GACAACAGCT TCTTGAGTTC TAAGGTGTTA GAACTCTGCG GTGACCTTCC TATTTTCTGG 
CTTAAACCAA CCTATCCAAA AGAAATCCAG AGGGAAAGAA GAGAAGTGGT AAGAAAAATT 
GTTCCAACTA CCACAAAAAG ACCACACAGT GGACCACGGA GCAACCCAGG CGCTGGAAGA 
CTGAATAATG AAACCAGACC CAGTGTTCAA GAGGACTCAC AAGCCTTCAA TCCTGATAAT 
CCTTATCATC AGGAAGGGGA AAGCATGACA TTCGACCCTA GACTGGATCA CGAAGGAATC 
TGTTGTATAG AATGTAGGCG GAGCTACACC CACTGCCAGA AGATCTGTGA ACCCCTGGGG 
GGCTATTACC CATGGCCTTA TAATTATCAA GGCTGCCGTT CGGCCTGCAG AGTCATCATG 
CCATGTAGCT GGTGGGTGGC CCGTATCTTG GGCATGGTGT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

CNMD ( XM_011534897.2 ) cDNA ORF clone, Homo sapiens(human) -> XP_011533199.1 Homo sapiens chondromodulin (CNMD), transcript variant X1, mRNA.

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CloneID	OHu64665
Clone ID Related Accession (Same CDS sequence)	XM_011534897.2
Accession Version	XM_011534897.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1098bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	leukocyte cell-derived chemotaxin 1 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000013.11) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 6, 2016 this sequence version replaced XM_011534897.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGCCCTGCA CGTCGGGGCA GCGGGACAGA TCCCAGGGTG CCCAGGGAGT CTCCAAGTGC 
CTCACTCCTC CCGCCGCAAA CATGACAGAG AACTCCGACA AAGTTCCCAT TGCCCTGGTG 
GGACCTGATG ACGTGGAATT CTGCAGCCCC CCGGCGTACG CTACGCTGAC GGTGAAGCCC 
TCCAGCCCCG CGCGGCTGCT CAAGGTGGGA GCCGTGGTCC TCATTTCGGG AGCTGTGCTG 
CTGCTCTTTG GGGCCATCGG GGCCTTCTAC TTCTGGAAGG GGAGCGACAG TCACATTTAC 
AATGTCCATT ACACCATGAG TATCAATGGG AAATTACAAG ATGGGTCAAT GGAAATAGAC 
GCTGGGAACA ACTTGGAGAC CTTTAAAATG GGAAGTGGAG CTGAAGAAGC AATTGCAGTT 
AATGATTTCC AGAATGGCAT CACAGGAATT CGTTTTGCTG GAGGAGAGAA GTGCTACATT 
AAAGCGCAAG TGAAGGCTCG TATTCCTGAG GTGGGCGCCG TGACCAAACA GAGCATCTCC 
TCCAAACTGG AAGGCAAGAT CATGCCAGTC AAATATGAAG AAAATTCTCT TATCTGGGTG 
GCTGTAGATC AGCCTGTGAA GGACAACAGC TTCTTGAGTT CTAAGGTGTT AGAACTCTGC 
GGTGACCTTC CTATTTTCTG GCTTAAACCA ACCTATCCAA AAGAAATTTT TGCAGAAATC 
CAGAGGGAAA GAAGAGAAGT GGTAAGAAAA ATTGTTCCAA CTACCACAAA AAGACCACAC 
AGTGGACCAC GGAGCAACCC AGGCGCTGGA AGACTGAATA ATGAAACCAG ACCCAGTGTT 
CAAGAGGACT CACAAGCCTT CAATCCTGAT AATCCTTATC ATCAGCAGGA AGGGGAAAGC 
ATGACATTCG ACCCTAGACT GGATCACGAA GGAATCTGTT GTATAGAATG TAGGCGGAGC 
TACACCCACT GCCAGAAGAT CTGTGAACCC CTGGGGGGCT ATTACCCATG GCCTTATAAT 
TATCAAGGCT GCCGTTCGGC CTGCAGAGTC ATCATGCCAT GTAGCTGGTG GGTGGCCCGT 
ATCTTGGGCA TGGTGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_011533199.1
CDS	29..1126
Translation	MPCTSGQRDRSQGAQGVSKCLTPPAANMTENSDKVPIALVGPDDVEFCSPPAYATLTVKPSSPARLLKVGAVVLISGAVLLLFGAIGAFYFWKGSDSHIYNVHYTMSINGKLQDGSMEIDAGNNLETFKMGSGAEEAIAVNDFQNGITGIRFAGGEKCYIKAQVKARIPEVGAVTKQSISSKLEGKIMPVKYEENSLIWVAVDQPVKDNSFLSSKVLELCGDLPIFWLKPTYPKEIFAEIQRERREVVRKIVPTTTKRPHSGPRSNPGAGRLNNETRPSVQEDSQAFNPDNPYHQQEGESMTFDPRLDHEGICCIECRRSYTHCQKICEPLGGYYPWPYNYQGCRSACRVIMPCSWWVARILGMV

Target ORF information:

RefSeq Version	XM_011534897.2
Organism	Homo sapiens(human)
Definition	Homo sapiens chondromodulin (CNMD), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011534897.2

ORF Insert Sequence:

ATGCCCTGCA CGTCGGGGCA GCGGGACAGA TCCCAGGGTG CCCAGGGAGT CTCCAAGTGC 
CTCACTCCTC CCGCCGCAAA CATGACAGAG AACTCCGACA AAGTTCCCAT TGCCCTGGTG 
GGACCTGATG ACGTGGAATT CTGCAGCCCC CCGGCGTACG CTACGCTGAC GGTGAAGCCC 
TCCAGCCCCG CGCGGCTGCT CAAGGTGGGA GCCGTGGTCC TCATTTCGGG AGCTGTGCTG 
CTGCTCTTTG GGGCCATCGG GGCCTTCTAC TTCTGGAAGG GGAGCGACAG TCACATTTAC 
AATGTCCATT ACACCATGAG TATCAATGGG AAATTACAAG ATGGGTCAAT GGAAATAGAC 
GCTGGGAACA ACTTGGAGAC CTTTAAAATG GGAAGTGGAG CTGAAGAAGC AATTGCAGTT 
AATGATTTCC AGAATGGCAT CACAGGAATT CGTTTTGCTG GAGGAGAGAA GTGCTACATT 
AAAGCGCAAG TGAAGGCTCG TATTCCTGAG GTGGGCGCCG TGACCAAACA GAGCATCTCC 
TCCAAACTGG AAGGCAAGAT CATGCCAGTC AAATATGAAG AAAATTCTCT TATCTGGGTG 
GCTGTAGATC AGCCTGTGAA GGACAACAGC TTCTTGAGTT CTAAGGTGTT AGAACTCTGC 
GGTGACCTTC CTATTTTCTG GCTTAAACCA ACCTATCCAA AAGAAATTTT TGCAGAAATC 
CAGAGGGAAA GAAGAGAAGT GGTAAGAAAA ATTGTTCCAA CTACCACAAA AAGACCACAC 
AGTGGACCAC GGAGCAACCC AGGCGCTGGA AGACTGAATA ATGAAACCAG ACCCAGTGTT 
CAAGAGGACT CACAAGCCTT CAATCCTGAT AATCCTTATC ATCAGCAGGA AGGGGAAAGC 
ATGACATTCG ACCCTAGACT GGATCACGAA GGAATCTGTT GTATAGAATG TAGGCGGAGC 
TACACCCACT GCCAGAAGAT CTGTGAACCC CTGGGGGGCT ATTACCCATG GCCTTATAAT 
TATCAAGGCT GCCGTTCGGC CTGCAGAGTC ATCATGCCAT GTAGCTGGTG GGTGGCCCGT 
ATCTTGGGCA TGGTGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

CNMD ( XM_011534898.2 ) cDNA ORF clone, Homo sapiens(human) -> XP_011533200.1 Homo sapiens chondromodulin (CNMD), transcript variant X2, mRNA.

Price & Availability↑

CloneID	OHu64666
Clone ID Related Accession (Same CDS sequence)	XM_011534898.2
Accession Version	XM_011534898.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1095bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	leukocyte cell-derived chemotaxin 1 isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000013.11) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 6, 2016 this sequence version replaced XM_011534898.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGCCCTGCA CGTCGGGGCA GCGGGACAGA TCCCAGGGTG CCCAGGGAGT CTCCAAGTGC 
CTCACTCCTC CCGCCGCAAA CATGACAGAG AACTCCGACA AAGTTCCCAT TGCCCTGGTG 
GGACCTGATG ACGTGGAATT CTGCAGCCCC CCGGCGTACG CTACGCTGAC GGTGAAGCCC 
TCCAGCCCCG CGCGGCTGCT CAAGGTGGGA GCCGTGGTCC TCATTTCGGG AGCTGTGCTG 
CTGCTCTTTG GGGCCATCGG GGCCTTCTAC TTCTGGAAGG GGAGCGACAG TCACATTTAC 
AATGTCCATT ACACCATGAG TATCAATGGG AAATTACAAG ATGGGTCAAT GGAAATAGAC 
GCTGGGAACA ACTTGGAGAC CTTTAAAATG GGAAGTGGAG CTGAAGAAGC AATTGCAGTT 
AATGATTTCC AGAATGGCAT CACAGGAATT CGTTTTGCTG GAGGAGAGAA GTGCTACATT 
AAAGCGCAAG TGAAGGCTCG TATTCCTGAG GTGGGCGCCG TGACCAAACA GAGCATCTCC 
TCCAAACTGG AAGGCAAGAT CATGCCAGTC AAATATGAAG AAAATTCTCT TATCTGGGTG 
GCTGTAGATC AGCCTGTGAA GGACAACAGC TTCTTGAGTT CTAAGGTGTT AGAACTCTGC 
GGTGACCTTC CTATTTTCTG GCTTAAACCA ACCTATCCAA AAGAAATTTT TGCAGAAATC 
CAGAGGGAAA GAAGAGAAGT GGTAAGAAAA ATTGTTCCAA CTACCACAAA AAGACCACAC 
AGTGGACCAC GGAGCAACCC AGGCGCTGGA AGACTGAATA ATGAAACCAG ACCCAGTGTT 
CAAGAGGACT CACAAGCCTT CAATCCTGAT AATCCTTATC ATCAGGAAGG GGAAAGCATG 
ACATTCGACC CTAGACTGGA TCACGAAGGA ATCTGTTGTA TAGAATGTAG GCGGAGCTAC 
ACCCACTGCC AGAAGATCTG TGAACCCCTG GGGGGCTATT ACCCATGGCC TTATAATTAT 
CAAGGCTGCC GTTCGGCCTG CAGAGTCATC ATGCCATGTA GCTGGTGGGT GGCCCGTATC 
TTGGGCATGG TGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_011533200.1
CDS	30..1124
Translation	MPCTSGQRDRSQGAQGVSKCLTPPAANMTENSDKVPIALVGPDDVEFCSPPAYATLTVKPSSPARLLKVGAVVLISGAVLLLFGAIGAFYFWKGSDSHIYNVHYTMSINGKLQDGSMEIDAGNNLETFKMGSGAEEAIAVNDFQNGITGIRFAGGEKCYIKAQVKARIPEVGAVTKQSISSKLEGKIMPVKYEENSLIWVAVDQPVKDNSFLSSKVLELCGDLPIFWLKPTYPKEIFAEIQRERREVVRKIVPTTTKRPHSGPRSNPGAGRLNNETRPSVQEDSQAFNPDNPYHQEGESMTFDPRLDHEGICCIECRRSYTHCQKICEPLGGYYPWPYNYQGCRSACRVIMPCSWWVARILGMV

Target ORF information:

RefSeq Version	XM_011534898.2
Organism	Homo sapiens(human)
Definition	Homo sapiens chondromodulin (CNMD), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011534898.2

ORF Insert Sequence:

ATGCCCTGCA CGTCGGGGCA GCGGGACAGA TCCCAGGGTG CCCAGGGAGT CTCCAAGTGC 
CTCACTCCTC CCGCCGCAAA CATGACAGAG AACTCCGACA AAGTTCCCAT TGCCCTGGTG 
GGACCTGATG ACGTGGAATT CTGCAGCCCC CCGGCGTACG CTACGCTGAC GGTGAAGCCC 
TCCAGCCCCG CGCGGCTGCT CAAGGTGGGA GCCGTGGTCC TCATTTCGGG AGCTGTGCTG 
CTGCTCTTTG GGGCCATCGG GGCCTTCTAC TTCTGGAAGG GGAGCGACAG TCACATTTAC 
AATGTCCATT ACACCATGAG TATCAATGGG AAATTACAAG ATGGGTCAAT GGAAATAGAC 
GCTGGGAACA ACTTGGAGAC CTTTAAAATG GGAAGTGGAG CTGAAGAAGC AATTGCAGTT 
AATGATTTCC AGAATGGCAT CACAGGAATT CGTTTTGCTG GAGGAGAGAA GTGCTACATT 
AAAGCGCAAG TGAAGGCTCG TATTCCTGAG GTGGGCGCCG TGACCAAACA GAGCATCTCC 
TCCAAACTGG AAGGCAAGAT CATGCCAGTC AAATATGAAG AAAATTCTCT TATCTGGGTG 
GCTGTAGATC AGCCTGTGAA GGACAACAGC TTCTTGAGTT CTAAGGTGTT AGAACTCTGC 
GGTGACCTTC CTATTTTCTG GCTTAAACCA ACCTATCCAA AAGAAATTTT TGCAGAAATC 
CAGAGGGAAA GAAGAGAAGT GGTAAGAAAA ATTGTTCCAA CTACCACAAA AAGACCACAC 
AGTGGACCAC GGAGCAACCC AGGCGCTGGA AGACTGAATA ATGAAACCAG ACCCAGTGTT 
CAAGAGGACT CACAAGCCTT CAATCCTGAT AATCCTTATC ATCAGGAAGG GGAAAGCATG 
ACATTCGACC CTAGACTGGA TCACGAAGGA ATCTGTTGTA TAGAATGTAG GCGGAGCTAC 
ACCCACTGCC AGAAGATCTG TGAACCCCTG GGGGGCTATT ACCCATGGCC TTATAATTAT 
CAAGGCTGCC GTTCGGCCTG CAGAGTCATC ATGCCATGTA GCTGGTGGGT GGCCCGTATC 
TTGGGCATGG TGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

CNMD ( XM_011534899.2 ) cDNA ORF clone, Homo sapiens(human) -> XP_011533201.1 Homo sapiens chondromodulin (CNMD), transcript variant X3, mRNA.

Price & Availability↑

CloneID	OHu64667
Clone ID Related Accession (Same CDS sequence)	XM_011534899.2
Accession Version	XM_011534899.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 984bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	leukocyte cell-derived chemotaxin 1 isoform X3
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000013.11) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 6, 2016 this sequence version replaced XM_011534899.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGCCCTGCA CGTCGGGGCA GCGGGACAGA TCCCAGGGTG CCCAGGGAGT CTCCAAGTGC 
CTCACTCCTC CCGCCGCAAA CATGACAGAG AACTCCGACA AAGTTCCCAT TGCCCTGGTG 
GGACCTGATG ACGTGGAATT CTGCAGCCCC CCGGCGTACG CTACGCTGAC GGTGAAGCCC 
TCCAGCCCCG CGCGGCTGCT CAAGGTGGGA GCCGTGGTCC TCATTTCGGG AGCTGTGCTG 
CTGCTCTTTG GGGCCATCGG GGCCTTCTAC TTCTGGAAGG GGAGCGACAG TCACATTTAC 
AATGTCCATT ACACCATGAG TATCAATGGG AAATTACAAG ATGGGTCAAT GGAAATAGAC 
GCTGGGAACA ACTTGGAGAC CTTTAAAATG GGAAGTGGAG CTGAAGAAGC AATTGCAGTT 
AATGATTTCC AGAATGAAGG CAAGATCATG CCAGTCAAAT ATGAAGAAAA TTCTCTTATC 
TGGGTGGCTG TAGATCAGCC TGTGAAGGAC AACAGCTTCT TGAGTTCTAA GGTGTTAGAA 
CTCTGCGGTG ACCTTCCTAT TTTCTGGCTT AAACCAACCT ATCCAAAAGA AATTTTTGCA 
GAAATCCAGA GGGAAAGAAG AGAAGTGGTA AGAAAAATTG TTCCAACTAC CACAAAAAGA 
CCACACAGTG GACCACGGAG CAACCCAGGC GCTGGAAGAC TGAATAATGA AACCAGACCC 
AGTGTTCAAG AGGACTCACA AGCCTTCAAT CCTGATAATC CTTATCATCA GCAGGAAGGG 
GAAAGCATGA CATTCGACCC TAGACTGGAT CACGAAGGAA TCTGTTGTAT AGAATGTAGG 
CGGAGCTACA CCCACTGCCA GAAGATCTGT GAACCCCTGG GGGGCTATTA CCCATGGCCT 
TATAATTATC AAGGCTGCCG TTCGGCCTGC AGAGTCATCA TGCCATGTAG CTGGTGGGTG 
GCCCGTATCT TGGGCATGGT GTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_011533201.1
CDS	31..1014
Translation	MPCTSGQRDRSQGAQGVSKCLTPPAANMTENSDKVPIALVGPDDVEFCSPPAYATLTVKPSSPARLLKVGAVVLISGAVLLLFGAIGAFYFWKGSDSHIYNVHYTMSINGKLQDGSMEIDAGNNLETFKMGSGAEEAIAVNDFQNEGKIMPVKYEENSLIWVAVDQPVKDNSFLSSKVLELCGDLPIFWLKPTYPKEIFAEIQRERREVVRKIVPTTTKRPHSGPRSNPGAGRLNNETRPSVQEDSQAFNPDNPYHQQEGESMTFDPRLDHEGICCIECRRSYTHCQKICEPLGGYYPWPYNYQGCRSACRVIMPCSWWVARILGMV

Target ORF information:

RefSeq Version	XM_011534899.2
Organism	Homo sapiens(human)
Definition	Homo sapiens chondromodulin (CNMD), transcript variant X3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011534899.2

ORF Insert Sequence:

ATGCCCTGCA CGTCGGGGCA GCGGGACAGA TCCCAGGGTG CCCAGGGAGT CTCCAAGTGC 
CTCACTCCTC CCGCCGCAAA CATGACAGAG AACTCCGACA AAGTTCCCAT TGCCCTGGTG 
GGACCTGATG ACGTGGAATT CTGCAGCCCC CCGGCGTACG CTACGCTGAC GGTGAAGCCC 
TCCAGCCCCG CGCGGCTGCT CAAGGTGGGA GCCGTGGTCC TCATTTCGGG AGCTGTGCTG 
CTGCTCTTTG GGGCCATCGG GGCCTTCTAC TTCTGGAAGG GGAGCGACAG TCACATTTAC 
AATGTCCATT ACACCATGAG TATCAATGGG AAATTACAAG ATGGGTCAAT GGAAATAGAC 
GCTGGGAACA ACTTGGAGAC CTTTAAAATG GGAAGTGGAG CTGAAGAAGC AATTGCAGTT 
AATGATTTCC AGAATGAAGG CAAGATCATG CCAGTCAAAT ATGAAGAAAA TTCTCTTATC 
TGGGTGGCTG TAGATCAGCC TGTGAAGGAC AACAGCTTCT TGAGTTCTAA GGTGTTAGAA 
CTCTGCGGTG ACCTTCCTAT TTTCTGGCTT AAACCAACCT ATCCAAAAGA AATTTTTGCA 
GAAATCCAGA GGGAAAGAAG AGAAGTGGTA AGAAAAATTG TTCCAACTAC CACAAAAAGA 
CCACACAGTG GACCACGGAG CAACCCAGGC GCTGGAAGAC TGAATAATGA AACCAGACCC 
AGTGTTCAAG AGGACTCACA AGCCTTCAAT CCTGATAATC CTTATCATCA GCAGGAAGGG 
GAAAGCATGA CATTCGACCC TAGACTGGAT CACGAAGGAA TCTGTTGTAT AGAATGTAGG 
CGGAGCTACA CCCACTGCCA GAAGATCTGT GAACCCCTGG GGGGCTATTA CCCATGGCCT 
TATAATTATC AAGGCTGCCG TTCGGCCTGC AGAGTCATCA TGCCATGTAG CTGGTGGGTG 
GCCCGTATCT TGGGCATGGT GTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

CNMD ( XM_011534900.2 ) cDNA ORF clone, Homo sapiens(human) -> XP_011533202.1 Homo sapiens chondromodulin (CNMD), transcript variant X4, mRNA.

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CloneID	OHu64668
Clone ID Related Accession (Same CDS sequence)	XM_011534900.2
Accession Version	XM_011534900.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 972bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	leukocyte cell-derived chemotaxin 1 isoform X4
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000013.11) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 6, 2016 this sequence version replaced XM_011534900.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGCCCTGCA CGTCGGGGCA GCGGGACAGA TCCCAGGGTG CCCAGGGAGT CTCCAAGTGC 
CTCACTCCTC CCGCCGCAAA CATGACAGAG AACTCCGACA AAGTTCCCAT TGCCCTGGTG 
GGACCTGATG ACGTGGAATT CTGCAGCCCC CCGGCGTACG CTACGCTGAC GGTGAAGCCC 
TCCAGCCCCG CGCGGCTGCT CAAGGTGGGA GCCGTGGTCC TCATTTCGGG AGCTGTGCTG 
CTGCTCTTTG GGGCCATCGG GGCCTTCTAC TTCTGGAAGG GGAGCGACAG TCACATTTAC 
AATGTCCATT ACACCATGAG TATCAATGGG AAATTACAAG ATGGGTCAAT GGAAATAGAC 
GCTGGGAACA ACTTGGAGAC CTTTAAAATG GGAAGTGGAG CTGAAGAAGC AATTGCAGTT 
AATGATTTCC AGAATGAAGG CAAGATCATG CCAGTCAAAT ATGAAGAAAA TTCTCTTATC 
TGGGTGGCTG TAGATCAGCC TGTGAAGGAC AACAGCTTCT TGAGTTCTAA GGTGTTAGAA 
CTCTGCGGTG ACCTTCCTAT TTTCTGGCTT AAACCAACCT ATCCAAAAGA AATCCAGAGG 
GAAAGAAGAG AAGTGGTAAG AAAAATTGTT CCAACTACCA CAAAAAGACC ACACAGTGGA 
CCACGGAGCA ACCCAGGCGC TGGAAGACTG AATAATGAAA CCAGACCCAG TGTTCAAGAG 
GACTCACAAG CCTTCAATCC TGATAATCCT TATCATCAGC AGGAAGGGGA AAGCATGACA 
TTCGACCCTA GACTGGATCA CGAAGGAATC TGTTGTATAG AATGTAGGCG GAGCTACACC 
CACTGCCAGA AGATCTGTGA ACCCCTGGGG GGCTATTACC CATGGCCTTA TAATTATCAA 
GGCTGCCGTT CGGCCTGCAG AGTCATCATG CCATGTAGCT GGTGGGTGGC CCGTATCTTG 
GGCATGGTGT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_011533202.1
CDS	29..1000
Translation	MPCTSGQRDRSQGAQGVSKCLTPPAANMTENSDKVPIALVGPDDVEFCSPPAYATLTVKPSSPARLLKVGAVVLISGAVLLLFGAIGAFYFWKGSDSHIYNVHYTMSINGKLQDGSMEIDAGNNLETFKMGSGAEEAIAVNDFQNEGKIMPVKYEENSLIWVAVDQPVKDNSFLSSKVLELCGDLPIFWLKPTYPKEIQRERREVVRKIVPTTTKRPHSGPRSNPGAGRLNNETRPSVQEDSQAFNPDNPYHQQEGESMTFDPRLDHEGICCIECRRSYTHCQKICEPLGGYYPWPYNYQGCRSACRVIMPCSWWVARILGMV

Target ORF information:

RefSeq Version	XM_011534900.2
Organism	Homo sapiens(human)
Definition	Homo sapiens chondromodulin (CNMD), transcript variant X4, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011534900.2

ORF Insert Sequence:

ATGCCCTGCA CGTCGGGGCA GCGGGACAGA TCCCAGGGTG CCCAGGGAGT CTCCAAGTGC 
CTCACTCCTC CCGCCGCAAA CATGACAGAG AACTCCGACA AAGTTCCCAT TGCCCTGGTG 
GGACCTGATG ACGTGGAATT CTGCAGCCCC CCGGCGTACG CTACGCTGAC GGTGAAGCCC 
TCCAGCCCCG CGCGGCTGCT CAAGGTGGGA GCCGTGGTCC TCATTTCGGG AGCTGTGCTG 
CTGCTCTTTG GGGCCATCGG GGCCTTCTAC TTCTGGAAGG GGAGCGACAG TCACATTTAC 
AATGTCCATT ACACCATGAG TATCAATGGG AAATTACAAG ATGGGTCAAT GGAAATAGAC 
GCTGGGAACA ACTTGGAGAC CTTTAAAATG GGAAGTGGAG CTGAAGAAGC AATTGCAGTT 
AATGATTTCC AGAATGAAGG CAAGATCATG CCAGTCAAAT ATGAAGAAAA TTCTCTTATC 
TGGGTGGCTG TAGATCAGCC TGTGAAGGAC AACAGCTTCT TGAGTTCTAA GGTGTTAGAA 
CTCTGCGGTG ACCTTCCTAT TTTCTGGCTT AAACCAACCT ATCCAAAAGA AATCCAGAGG 
GAAAGAAGAG AAGTGGTAAG AAAAATTGTT CCAACTACCA CAAAAAGACC ACACAGTGGA 
CCACGGAGCA ACCCAGGCGC TGGAAGACTG AATAATGAAA CCAGACCCAG TGTTCAAGAG 
GACTCACAAG CCTTCAATCC TGATAATCCT TATCATCAGC AGGAAGGGGA AAGCATGACA 
TTCGACCCTA GACTGGATCA CGAAGGAATC TGTTGTATAG AATGTAGGCG GAGCTACACC 
CACTGCCAGA AGATCTGTGA ACCCCTGGGG GGCTATTACC CATGGCCTTA TAATTATCAA 
GGCTGCCGTT CGGCCTGCAG AGTCATCATG CCATGTAGCT GGTGGGTGGC CCGTATCTTG 
GGCATGGTGT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Chondromodulin?I suppresses tumorigenesis of human osteosarcoma cells.
Molecular medicine reports16(6)8542-8548(2017 Dec)
Lin X,Wang L,Wang F

The endochondral bone protein CHM1 sustains an undifferentiated, invasive phenotype, promoting lung metastasis in Ewing sarcoma.
Molecular oncology11(9)1288-1301(2017 Sep)
von Heyking K,Calzada-Wack J,G?llner S,Neff F,Schmidt O,Hensel T,Schirmer D,Fasan A,Esposito I,M?ller-Tidow C,Sorensen PH,Burdach S,Richter GHS

Transfection of chondromodulin I into human breast cancer cells and its effect on the inhibition of cancer cell growth.
Molecular medicine reports13(5)4303-8(2016 May)
Shao J,Gan L,Wang J

Chondromodulin-1 functions as a tumor suppressor in gastric adenocarcinoma.
International journal of oncology47(3)941-50(2015 Sep)
Zhang P,Wang Y,Xu P,Song S,Zhu X,Shi Z,Gao S,Feng X

The N-terminal cleavage of chondromodulin-I in growth-plate cartilage at the hypertrophic and calcified zones during bone development.
PloS one9(4)e94239(2014)
Miura S,Kondo J,Takimoto A,Sano-Takai H,Guo L,Shukunami C,Tanaka H,Hiraki Y

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CNMD cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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