OGFR cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	OGFR
Entrez Gene ID	11054
Full Name	opioid growth factor receptor
General protein information	Preferred Names opioid growth factor receptor Names opioid growth factor receptor protein 7-60 zeta-type opioid receptor
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 20 Map Location: 20q13.33
Summary	The protein encoded by this gene is a receptor for opioid growth factor (OGF), also known as [Met(5)]-enkephalin. OGF is a negative regulator of cell proliferation and tissue organization in a variety of processes. The encoded unbound receptor for OGF has been localized to the outer nuclear envelope, where it binds OGF and is translocated into the nucleus. The coding sequence of this gene contains a polymorphic region of 60 nt tandem imperfect repeat units. Several transcripts containing between zero and eight repeat units have been reported. [provided by RefSeq, Jul 2008].
Disorder MIM:	606459

mRNA and Protein(s)

mRNA	Protein	Name
NM_007346.3	NP_031372.2	opioid growth factor receptor
NM_007346.4	NP_031372.2	opioid growth factor receptor

Pathways from BioSystems

Homologies

Pan troglodytes (chimpanzee)	OGFR	XP_001146234.2
Mus musculus (house mouse)	Ogfr	NP_113550.3
Rattus norvegicus (Norway rat)	Ogfr	NP_445792.2
	OGFR	XP_001087181.1
Canis lupus familiaris (dog)	OGFR	XP_005635325.1
Homo sapiens (human)	OGFR	NP_031372.2
Bos taurus (cattle)	OGFR	NP_001070487.1
Gallus gallus (chicken)	OGFR	XP_425708.3

Gene Ontology
Bibliography

Related articles in PubMed

Morphine Suppresses Lung Cancer Cell Proliferation Through the Interaction with Opioid Growth Factor Receptor: An In Vitro and Human Lung Tissue Study.
Kim JY, Ahn HJ, Kim JK, Kim J, Lee SH, Chae HB
Anesthesia and analgesia123(6)1429-1436(2016 12)

Antagonism of the Met5-enkephalin-opioid growth factor receptor-signaling axis promotes MSC to differentiate into osteoblasts.
Thakur NA, DeBoyace SD, Margulies BS
Journal of orthopaedic research : official publication of the Orthopaedic Research Society34(7)1195-205(2016 07)

Peripheral opioid antagonist enhances the effect of anti-tumor drug by blocking a cell growth-suppressive pathway in vivo.
Suzuki M, Chiwaki F, Sawada Y, Ashikawa M, Aoyagi K, Fujita T, Yanagihara K, Komatsu M, Narita M, Suzuki T, Nagase H, Kushima R, Sakamoto H, Fukagawa T, Katai H, Nakagama H, Yoshida T, Uezono Y, Sasaki H
PloS one10(4)e0123407(2015)

Targeting the opioid growth factor: opioid growth factor receptor axis for treatment of human ovarian cancer.
Zagon IS, Donahue R, McLaughlin PJ
Experimental biology and medicine (Maywood, N.J.)238(5)579-87(2013 May)

Under-expression of the opioid growth factor receptor promotes progression of human ovarian cancer.
Donahue RN, McLaughlin PJ, Zagon IS
Experimental biology and medicine (Maywood, N.J.)237(2)167-77(2012 Feb)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Morphine interacts with OGFR and may suppress lung cancer proliferation and progression.
Title: Morphine Suppresses Lung Cancer Cell Proliferation Through the Interaction with Opioid Growth Factor Receptor: An In Vitro and Human Lung Tissue Study.

The blockade of OGF signaling by MNTX releases cells from their arrest and boosts the effect of Doc
Title: Peripheral opioid antagonist enhances the effect of anti-tumor drug by blocking a cell growth-suppressive pathway in vivo.

The OGF-OGFr axis may be a feasible target for treatment of cancer of the ovary (i) in a prophylactic fashion, (ii) following cytoreduction or (iii) in conjunction with standard chemotherapy for additive effectiveness
Title: Targeting the opioid growth factor: opioid growth factor receptor axis for treatment of human ovarian cancer.

OGF-OGFr axis is a determinant of the progression of human ovarian cancer
Title: Under-expression of the opioid growth factor receptor promotes progression of human ovarian cancer.

These data are the first to report that theOGFr system is a native biological regulator of cell proliferation in Hepatocellular carcinoma
Title: The opioid growth factor-opioid growth factor receptor axis regulates cell proliferation of human hepatocellular cancer.

The following OGFR gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the OGFR cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu18929	NM_007346.4 Latest version!	Homo sapiens opioid growth factor receptor (OGFR), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$279.50-$391.30 $559.00
View Old Accession Versions >>
OHu18929	NM_007346.3	Homo sapiens opioid growth factor receptor (OGFR), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$391.30 $559.00
Hide Old Accession Versions >>

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***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

OGFR ( NM_007346.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_031372.2 Homo sapiens opioid growth factor receptor (OGFR), mRNA.

Price & Availability↑

CloneID	OHu18929
Clone ID Related Accession (Same CDS sequence)	NM_007346.3 , NM_007346.4
Accession Version	NM_007346.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2034bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-29
Organism	Homo sapiens(human)
Product	opioid growth factor receptor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AL035669.43 and AF172453.2. This sequence is a reference standard in the RefSeqGene project. On Nov 22, 2018 this sequence version replaced NM_007346.3. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK022234.1, AF172451.2 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000290291.10/ ENSP00000290291.6 RefSeq Select criteria :: based on single protein-coding transcript ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGGACGACC CCGACTGCGA CTCCACCTGG GAGGAGGACG AGGAGGATGC GGAGGACGCG 
GAGGACGAGG ACTGCGAGGA CGGCGAGGCC GCCGGCGCGA GGGACGCGGA CGCAGGGGAC 
GAGGACGAGG AGTCGGAGGA GCCGCGGGCG GCGCGGCCCA GCTCGTTCCA GTCCAGAATG 
ACAGGGTCCA GAAACTGGCG AGCCACGAGG GACATGTGTA GGTATCGGCA CAACTATCCG 
GATCTGGTGG AACGAGACTG CAATGGGGAC ACGCCAAACC TGAGTTTCTA CAGAAATGAG 
ATCCGCTTCC TGCCCAACGG CTGTTTCATT GAGGACATTC TTCAGAACTG GACGGACAAC 
TATGACCTCC TTGAGGACAA TCACTCCTAC ATCCAGTGGC TGTTTCCTCT GCGAGAACCA 
GGAGTGAACT GGCATGCCAA GCCCCTCACG CTCAGGGAGG TCGAGGTGTT TAAAAGCTCC 
CAGGAGATCC AGGAGCGGCT TGTCCGGGCC TACGAGCTCA TGCTGGGCTT CTACGGGATC 
CGGCTGGAGG ACCGAGGCAC GGGCACGGTG GGCCGAGCAC AGAACTACCA GAAGCGCTTC 
CAGAACCTGA ACTGGCGCAG CCACAACAAC CTCCGCATCA CACGCATCCT CAAGTCGCTG 
GGTGAGCTGG GCCTCGAGCA CTTCCAGGCG CCGCTGGTCC GCTTCTTCCT GGAGGAGACG 
CTGGTGCGGC GGGAGCTGCC GGGGGTGCGG CAGAGTGCCC TGGACTACTT CATGTTCGCC 
GTGCGCTGCC GACACCAGCG CCGCCAGCTG GTGCACTTCG CCTGGGAGCA CTTCCGGCCC 
CGCTGCAAGT TCGTCTGGGG GCCCCAAGAC AAGCTGCGGA GGTTCAAGCC CAGCTCTCTG 
CCCCATCCGC TCGAGGGCTC CAGGAAGGTG GAGGAGGAAG GAAGCCCCGG GGACCCCGAC 
CACGAGGCCA GCACCCAGGG TCGGACCTGT GGGCCAGAGC ATAGCAAGGG TGGGGGCAGG 
GTGGACGAGG GGCCCCAGCC ACGGAGCGTG GAGCCCCAGG ATGCGGGACC CCTGGAGAGG 
AGCCAGGGGG ATGAGGCAGG GGGCCACGGG GAAGATAGGC CGGAGCCCTT AAGCCCCAAA 
GAGAGCAAGA AGAGGAAGCT GGAGCTGAGC CGGCGGGAGC AGCCGCCCAC AGAGCCAGGC 
CCTCAGAGTG CCTCAGAGGT GGAGAAGATC GCTCTGAATT TGGAGGGGTG TGCCCTCAGC 
CAGGGCAGCC TCAGGACGGG GACCCAGGAA GTGGGCGGTC AGGACCCTGG GGAGGCAGTG 
CAGCCCTGCC GCCAACCCCT GGGAGCCAGG GTGGCCGACA AGGTGAGGAA GCGGAGGAAG 
GTGGATGAGG GTGCTGGGGA CAGTGCTGCG GTGGCCAGTG GTGGTGCCCA GACCTTGGCC 
CTTGCCGGGT CCCCTGCCCC ATCGGGGCAC CCCAAGGCTG GACACAGTGA GAACGGGGTT 
GAGGAGGACA CAGAAGGTCG AACGGGGCCC AAAGAAGGTA CCCCTGGGAG CCCATCGGAG 
ACCCCAGGCC CCAGCCCAGC AGGACCTGCA GGGGACGAGC CAGCCGAGAG CCCATCGGAG 
ACCCCAGGCC CCCGCCCAGC AGGACCTGCA GGGGACGAGC CAGCCGAGAG CCCATCGGAG 
ACCCCAGGCC CCCGCCCGGC AGGACCTGCA GGGGACGAGC CAGCCGAGAG CCCATCGGAG 
ACCCCAGGCC CCAGCCCGGC AGGACCTACA AGGGATGAGC CAGCCGAGAG CCCATCGGAG 
ACCCCAGGCC CCCGCCCGGC AGGACCTGCA GGGGACGAGC CAGCCGAGAG CCCATCGGAG 
ACCCCAGGCC CCCGCCCGGC AGGACCTGCA GGGGACGAGC CAGCCGAGAG CCCATCGGAG 
ACCCCAGGCC CCAGCCCGGC AGGACCTACA AGGGATGAGC CAGCCAAGGC GGGGGAGGCA 
GCAGAGTTGC AGGACGCAGA GGTGGAGTCT TCTGCCAAGT CTGGGAAGCC TTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_031372.2
CDS	26..2059
Translation	MDDPDCDSTWEEDEEDAEDAEDEDCEDGEAAGARDADAGDEDEESEEPRAARPSSFQSRMTGSRNWRATRDMCRYRHNYPDLVERDCNGDTPNLSFYRNEIRFLPNGCFIEDILQNWTDNYDLLEDNHSYIQWLFPLREPGVNWHAKPLTLREVEVFKSSQEIQERLVRAYELMLGFYGIRLEDRGTGTVGRAQNYQKRFQNLNWRSHNNLRITRILKSLGELGLEHFQAPLVRFFLEETLVRRELPGVRQSALDYFMFAVRCRHQRRQLVHFAWEHFRPRCKFVWGPQDKLRRFKPSSLPHPLEGSRKVEEEGSPGDPDHEASTQGRTCGPEHSKGGGRVDEGPQPRSVEPQDAGPLERSQGDEAGGHGEDRPEPLSPKESKKRKLELSRREQPPTEPGPQSASEVEKIALNLEGCALSQGSLRTGTQEVGGQDPGEAVQPCRQPLGARVADKVRKRRKVDEGAGDSAAVASGGAQTLALAGSPAPSGHPKAGHSENGVEEDTEGRTGPKEGTPGSPSETPGPSPAGPAGDEPAESPSETPGPRPAGPAGDEPAESPSETPGPRPAGPAGDEPAESPSETPGPSPAGPTRDEPAESPSETPGPRPAGPAGDEPAESPSETPGPRPAGPAGDEPAESPSETPGPSPAGPTRDEPAKAGEAAELQDAEVESSAKSGKP

Target ORF information:

RefSeq Version	NM_007346.4
Organism	Homo sapiens(human)
Definition	Homo sapiens opioid growth factor receptor (OGFR), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_007346.4

ORF Insert Sequence:

ATGGACGACC CCGACTGCGA CTCCACCTGG GAGGAGGACG AGGAGGATGC GGAGGACGCG 
GAGGACGAGG ACTGCGAGGA CGGCGAGGCC GCCGGCGCGA GGGACGCGGA CGCAGGGGAC 
GAGGACGAGG AGTCGGAGGA GCCGCGGGCG GCGCGGCCCA GCTCGTTCCA GTCCAGAATG 
ACAGGGTCCA GAAACTGGCG AGCCACGAGG GACATGTGTA GGTATCGGCA CAACTATCCG 
GATCTGGTGG AACGAGACTG CAATGGGGAC ACGCCAAACC TGAGTTTCTA CAGAAATGAG 
ATCCGCTTCC TGCCCAACGG CTGTTTCATT GAGGACATTC TTCAGAACTG GACGGACAAC 
TATGACCTCC TTGAGGACAA TCACTCCTAC ATCCAGTGGC TGTTTCCTCT GCGAGAACCA 
GGAGTGAACT GGCATGCCAA GCCCCTCACG CTCAGGGAGG TCGAGGTGTT TAAAAGCTCC 
CAGGAGATCC AGGAGCGGCT TGTCCGGGCC TACGAGCTCA TGCTGGGCTT CTACGGGATC 
CGGCTGGAGG ACCGAGGCAC GGGCACGGTG GGCCGAGCAC AGAACTACCA GAAGCGCTTC 
CAGAACCTGA ACTGGCGCAG CCACAACAAC CTCCGCATCA CACGCATCCT CAAGTCGCTG 
GGTGAGCTGG GCCTCGAGCA CTTCCAGGCG CCGCTGGTCC GCTTCTTCCT GGAGGAGACG 
CTGGTGCGGC GGGAGCTGCC GGGGGTGCGG CAGAGTGCCC TGGACTACTT CATGTTCGCC 
GTGCGCTGCC GACACCAGCG CCGCCAGCTG GTGCACTTCG CCTGGGAGCA CTTCCGGCCC 
CGCTGCAAGT TCGTCTGGGG GCCCCAAGAC AAGCTGCGGA GGTTCAAGCC CAGCTCTCTG 
CCCCATCCGC TCGAGGGCTC CAGGAAGGTG GAGGAGGAAG GAAGCCCCGG GGACCCCGAC 
CACGAGGCCA GCACCCAGGG TCGGACCTGT GGGCCAGAGC ATAGCAAGGG TGGGGGCAGG 
GTGGACGAGG GGCCCCAGCC ACGGAGCGTG GAGCCCCAGG ATGCGGGACC CCTGGAGAGG 
AGCCAGGGGG ATGAGGCAGG GGGCCACGGG GAAGATAGGC CGGAGCCCTT AAGCCCCAAA 
GAGAGCAAGA AGAGGAAGCT GGAGCTGAGC CGGCGGGAGC AGCCGCCCAC AGAGCCAGGC 
CCTCAGAGTG CCTCAGAGGT GGAGAAGATC GCTCTGAATT TGGAGGGGTG TGCCCTCAGC 
CAGGGCAGCC TCAGGACGGG GACCCAGGAA GTGGGCGGTC AGGACCCTGG GGAGGCAGTG 
CAGCCCTGCC GCCAACCCCT GGGAGCCAGG GTGGCCGACA AGGTGAGGAA GCGGAGGAAG 
GTGGATGAGG GTGCTGGGGA CAGTGCTGCG GTGGCCAGTG GTGGTGCCCA GACCTTGGCC 
CTTGCCGGGT CCCCTGCCCC ATCGGGGCAC CCCAAGGCTG GACACAGTGA GAACGGGGTT 
GAGGAGGACA CAGAAGGTCG AACGGGGCCC AAAGAAGGTA CCCCTGGGAG CCCATCGGAG 
ACCCCAGGCC CCAGCCCAGC AGGACCTGCA GGGGACGAGC CAGCCGAGAG CCCATCGGAG 
ACCCCAGGCC CCCGCCCAGC AGGACCTGCA GGGGACGAGC CAGCCGAGAG CCCATCGGAG 
ACCCCAGGCC CCCGCCCGGC AGGACCTGCA GGGGACGAGC CAGCCGAGAG CCCATCGGAG 
ACCCCAGGCC CCAGCCCGGC AGGACCTACA AGGGATGAGC CAGCCGAGAG CCCATCGGAG 
ACCCCAGGCC CCCGCCCGGC AGGACCTGCA GGGGACGAGC CAGCCGAGAG CCCATCGGAG 
ACCCCAGGCC CCCGCCCGGC AGGACCTGCA GGGGACGAGC CAGCCGAGAG CCCATCGGAG 
ACCCCAGGCC CCAGCCCGGC AGGACCTACA AGGGATGAGC CAGCCAAGGC GGGGGAGGCA 
GCAGAGTTGC AGGACGCAGA GGTGGAGTCT TCTGCCAAGT CTGGGAAGCC TTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

OGFR ( NM_007346.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_031372.2 Homo sapiens opioid growth factor receptor (OGFR), mRNA.

Price & Availability↑

CloneID	OHu18929
Clone ID Related Accession (Same CDS sequence)	NM_007346.3 , NM_007346.4
Accession Version	NM_007346.3	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2034bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-10-02
Organism	Homo sapiens(human)
Product	opioid growth factor receptor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AL035669.43 and AF172453.2. This sequence is a reference standard in the RefSeqGene project. On Nov 30, 2016 this sequence version replaced NM_007346.2. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1163658.203153.1, AK022234.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGACGACC CCGACTGCGA CTCCACCTGG GAGGAGGACG AGGAGGATGC GGAGGACGCG 
GAGGACGAGG ACTGCGAGGA CGGCGAGGCC GCCGGCGCGA GGGACGCGGA CGCAGGGGAC 
GAGGACGAGG AGTCGGAGGA GCCGCGGGCG GCGCGGCCCA GCTCGTTCCA GTCCAGAATG 
ACAGGGTCCA GAAACTGGCG AGCCACGAGG GACATGTGTA GGTATCGGCA CAACTATCCG 
GATCTGGTGG AACGAGACTG CAATGGGGAC ACGCCAAACC TGAGTTTCTA CAGAAATGAG 
ATCCGCTTCC TGCCCAACGG CTGTTTCATT GAGGACATTC TTCAGAACTG GACGGACAAC 
TATGACCTCC TTGAGGACAA TCACTCCTAC ATCCAGTGGC TGTTTCCTCT GCGAGAACCA 
GGAGTGAACT GGCATGCCAA GCCCCTCACG CTCAGGGAGG TCGAGGTGTT TAAAAGCTCC 
CAGGAGATCC AGGAGCGGCT TGTCCGGGCC TACGAGCTCA TGCTGGGCTT CTACGGGATC 
CGGCTGGAGG ACCGAGGCAC GGGCACGGTG GGCCGAGCAC AGAACTACCA GAAGCGCTTC 
CAGAACCTGA ACTGGCGCAG CCACAACAAC CTCCGCATCA CACGCATCCT CAAGTCGCTG 
GGTGAGCTGG GCCTCGAGCA CTTCCAGGCG CCGCTGGTCC GCTTCTTCCT GGAGGAGACG 
CTGGTGCGGC GGGAGCTGCC GGGGGTGCGG CAGAGTGCCC TGGACTACTT CATGTTCGCC 
GTGCGCTGCC GACACCAGCG CCGCCAGCTG GTGCACTTCG CCTGGGAGCA CTTCCGGCCC 
CGCTGCAAGT TCGTCTGGGG GCCCCAAGAC AAGCTGCGGA GGTTCAAGCC CAGCTCTCTG 
CCCCATCCGC TCGAGGGCTC CAGGAAGGTG GAGGAGGAAG GAAGCCCCGG GGACCCCGAC 
CACGAGGCCA GCACCCAGGG TCGGACCTGT GGGCCAGAGC ATAGCAAGGG TGGGGGCAGG 
GTGGACGAGG GGCCCCAGCC ACGGAGCGTG GAGCCCCAGG ATGCGGGACC CCTGGAGAGG 
AGCCAGGGGG ATGAGGCAGG GGGCCACGGG GAAGATAGGC CGGAGCCCTT AAGCCCCAAA 
GAGAGCAAGA AGAGGAAGCT GGAGCTGAGC CGGCGGGAGC AGCCGCCCAC AGAGCCAGGC 
CCTCAGAGTG CCTCAGAGGT GGAGAAGATC GCTCTGAATT TGGAGGGGTG TGCCCTCAGC 
CAGGGCAGCC TCAGGACGGG GACCCAGGAA GTGGGCGGTC AGGACCCTGG GGAGGCAGTG 
CAGCCCTGCC GCCAACCCCT GGGAGCCAGG GTGGCCGACA AGGTGAGGAA GCGGAGGAAG 
GTGGATGAGG GTGCTGGGGA CAGTGCTGCG GTGGCCAGTG GTGGTGCCCA GACCTTGGCC 
CTTGCCGGGT CCCCTGCCCC ATCGGGGCAC CCCAAGGCTG GACACAGTGA GAACGGGGTT 
GAGGAGGACA CAGAAGGTCG AACGGGGCCC AAAGAAGGTA CCCCTGGGAG CCCATCGGAG 
ACCCCAGGCC CCAGCCCAGC AGGACCTGCA GGGGACGAGC CAGCCGAGAG CCCATCGGAG 
ACCCCAGGCC CCCGCCCAGC AGGACCTGCA GGGGACGAGC CAGCCGAGAG CCCATCGGAG 
ACCCCAGGCC CCCGCCCGGC AGGACCTGCA GGGGACGAGC CAGCCGAGAG CCCATCGGAG 
ACCCCAGGCC CCAGCCCGGC AGGACCTACA AGGGATGAGC CAGCCGAGAG CCCATCGGAG 
ACCCCAGGCC CCCGCCCGGC AGGACCTGCA GGGGACGAGC CAGCCGAGAG CCCATCGGAG 
ACCCCAGGCC CCCGCCCGGC AGGACCTGCA GGGGACGAGC CAGCCGAGAG CCCATCGGAG 
ACCCCAGGCC CCAGCCCGGC AGGACCTACA AGGGATGAGC CAGCCAAGGC GGGGGAGGCA 
GCAGAGTTGC AGGACGCAGA GGTGGAGTCT TCTGCCAAGT CTGGGAAGCC TTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_031372.2
CDS	61..2094
Translation	MDDPDCDSTWEEDEEDAEDAEDEDCEDGEAAGARDADAGDEDEESEEPRAARPSSFQSRMTGSRNWRATRDMCRYRHNYPDLVERDCNGDTPNLSFYRNEIRFLPNGCFIEDILQNWTDNYDLLEDNHSYIQWLFPLREPGVNWHAKPLTLREVEVFKSSQEIQERLVRAYELMLGFYGIRLEDRGTGTVGRAQNYQKRFQNLNWRSHNNLRITRILKSLGELGLEHFQAPLVRFFLEETLVRRELPGVRQSALDYFMFAVRCRHQRRQLVHFAWEHFRPRCKFVWGPQDKLRRFKPSSLPHPLEGSRKVEEEGSPGDPDHEASTQGRTCGPEHSKGGGRVDEGPQPRSVEPQDAGPLERSQGDEAGGHGEDRPEPLSPKESKKRKLELSRREQPPTEPGPQSASEVEKIALNLEGCALSQGSLRTGTQEVGGQDPGEAVQPCRQPLGARVADKVRKRRKVDEGAGDSAAVASGGAQTLALAGSPAPSGHPKAGHSENGVEEDTEGRTGPKEGTPGSPSETPGPSPAGPAGDEPAESPSETPGPRPAGPAGDEPAESPSETPGPRPAGPAGDEPAESPSETPGPSPAGPTRDEPAESPSETPGPRPAGPAGDEPAESPSETPGPRPAGPAGDEPAESPSETPGPSPAGPTRDEPAKAGEAAELQDAEVESSAKSGKP

Target ORF information:

RefSeq Version	NM_007346.3
Organism	Homo sapiens(human)
Definition	Homo sapiens opioid growth factor receptor (OGFR), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_007346.3

ORF Insert Sequence:

ATGGACGACC CCGACTGCGA CTCCACCTGG GAGGAGGACG AGGAGGATGC GGAGGACGCG 
GAGGACGAGG ACTGCGAGGA CGGCGAGGCC GCCGGCGCGA GGGACGCGGA CGCAGGGGAC 
GAGGACGAGG AGTCGGAGGA GCCGCGGGCG GCGCGGCCCA GCTCGTTCCA GTCCAGAATG 
ACAGGGTCCA GAAACTGGCG AGCCACGAGG GACATGTGTA GGTATCGGCA CAACTATCCG 
GATCTGGTGG AACGAGACTG CAATGGGGAC ACGCCAAACC TGAGTTTCTA CAGAAATGAG 
ATCCGCTTCC TGCCCAACGG CTGTTTCATT GAGGACATTC TTCAGAACTG GACGGACAAC 
TATGACCTCC TTGAGGACAA TCACTCCTAC ATCCAGTGGC TGTTTCCTCT GCGAGAACCA 
GGAGTGAACT GGCATGCCAA GCCCCTCACG CTCAGGGAGG TCGAGGTGTT TAAAAGCTCC 
CAGGAGATCC AGGAGCGGCT TGTCCGGGCC TACGAGCTCA TGCTGGGCTT CTACGGGATC 
CGGCTGGAGG ACCGAGGCAC GGGCACGGTG GGCCGAGCAC AGAACTACCA GAAGCGCTTC 
CAGAACCTGA ACTGGCGCAG CCACAACAAC CTCCGCATCA CACGCATCCT CAAGTCGCTG 
GGTGAGCTGG GCCTCGAGCA CTTCCAGGCG CCGCTGGTCC GCTTCTTCCT GGAGGAGACG 
CTGGTGCGGC GGGAGCTGCC GGGGGTGCGG CAGAGTGCCC TGGACTACTT CATGTTCGCC 
GTGCGCTGCC GACACCAGCG CCGCCAGCTG GTGCACTTCG CCTGGGAGCA CTTCCGGCCC 
CGCTGCAAGT TCGTCTGGGG GCCCCAAGAC AAGCTGCGGA GGTTCAAGCC CAGCTCTCTG 
CCCCATCCGC TCGAGGGCTC CAGGAAGGTG GAGGAGGAAG GAAGCCCCGG GGACCCCGAC 
CACGAGGCCA GCACCCAGGG TCGGACCTGT GGGCCAGAGC ATAGCAAGGG TGGGGGCAGG 
GTGGACGAGG GGCCCCAGCC ACGGAGCGTG GAGCCCCAGG ATGCGGGACC CCTGGAGAGG 
AGCCAGGGGG ATGAGGCAGG GGGCCACGGG GAAGATAGGC CGGAGCCCTT AAGCCCCAAA 
GAGAGCAAGA AGAGGAAGCT GGAGCTGAGC CGGCGGGAGC AGCCGCCCAC AGAGCCAGGC 
CCTCAGAGTG CCTCAGAGGT GGAGAAGATC GCTCTGAATT TGGAGGGGTG TGCCCTCAGC 
CAGGGCAGCC TCAGGACGGG GACCCAGGAA GTGGGCGGTC AGGACCCTGG GGAGGCAGTG 
CAGCCCTGCC GCCAACCCCT GGGAGCCAGG GTGGCCGACA AGGTGAGGAA GCGGAGGAAG 
GTGGATGAGG GTGCTGGGGA CAGTGCTGCG GTGGCCAGTG GTGGTGCCCA GACCTTGGCC 
CTTGCCGGGT CCCCTGCCCC ATCGGGGCAC CCCAAGGCTG GACACAGTGA GAACGGGGTT 
GAGGAGGACA CAGAAGGTCG AACGGGGCCC AAAGAAGGTA CCCCTGGGAG CCCATCGGAG 
ACCCCAGGCC CCAGCCCAGC AGGACCTGCA GGGGACGAGC CAGCCGAGAG CCCATCGGAG 
ACCCCAGGCC CCCGCCCAGC AGGACCTGCA GGGGACGAGC CAGCCGAGAG CCCATCGGAG 
ACCCCAGGCC CCCGCCCGGC AGGACCTGCA GGGGACGAGC CAGCCGAGAG CCCATCGGAG 
ACCCCAGGCC CCAGCCCGGC AGGACCTACA AGGGATGAGC CAGCCGAGAG CCCATCGGAG 
ACCCCAGGCC CCCGCCCGGC AGGACCTGCA GGGGACGAGC CAGCCGAGAG CCCATCGGAG 
ACCCCAGGCC CCCGCCCGGC AGGACCTGCA GGGGACGAGC CAGCCGAGAG CCCATCGGAG 
ACCCCAGGCC CCAGCCCGGC AGGACCTACA AGGGATGAGC CAGCCAAGGC GGGGGAGGCA 
GCAGAGTTGC AGGACGCAGA GGTGGAGTCT TCTGCCAAGT CTGGGAAGCC TTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Morphine Suppresses Lung Cancer Cell Proliferation Through the Interaction with Opioid Growth Factor Receptor: An In Vitro and Human Lung Tissue Study.
Anesthesia and analgesia123(6)1429-1436(2016 12)
Kim JY,Ahn HJ,Kim JK,Kim J,Lee SH,Chae HB

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OGFR cDNA ORF clone, Homo sapiens(human)

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