ADAP1 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	ADAP1
Entrez Gene ID	11033
Full Name	ArfGAP with dual PH domains 1
Synonyms	CENTA1,GCS1L,p42IP4
General protein information	Preferred Names ArfGAP with dual PH domains 1 Names arf-GAP with dual PH domain-containing protein 1 centaurin-alpha centaurin-alpha-1 cnt-a1 putative MAPK-activating protein PM25
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 7 Map Location: 7p22.3
Disorder MIM:	608114

mRNA and Protein(s)

mRNA	Protein	Name
NM_001284309.1	NP_001271238.1	arf-GAP with dual PH domain-containing protein 1 isoform 3
NM_001284310.1	NP_001271239.1	arf-GAP with dual PH domain-containing protein 1 isoform 3
NM_006869.3	NP_006860.1	arf-GAP with dual PH domain-containing protein 1 isoform 1
NM_006869.4	NP_006860.2	arf-GAP with dual PH domain-containing protein 1 isoform 1
NM_001284311.1	NP_001271240.1	arf-GAP with dual PH domain-containing protein 1 isoform 4
NM_001284308.1	NP_001271237.1	arf-GAP with dual PH domain-containing protein 1 isoform 2

Pathways from BioSystems

Homologies

Mus musculus (house mouse)	Adap1	NP_766311.2
Gallus gallus (chicken)	ADAP1	XP_414759.2
Xenopus tropicalis (tropical clawed frog)	LOC100037843	NP_001090758.1
Homo sapiens (human)	ADAP1	NP_006860.1
	ADAP1	XP_001084174.1
Canis lupus familiaris (dog)	ADAP1	XP_848516.1
Danio rerio (zebrafish)	zgc:92360	NP_001002715.1
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP007379	XP_308452.4
Pan troglodytes (chimpanzee)	ADAP1	XP_001175350.2
Rattus norvegicus (Norway rat)	Adap1	NP_598251.1
Bos taurus (cattle)	ADAP1	NP_776938.1

Gene Ontology
Bibliography

Related articles in PubMed

Functions of the neuron-specific protein ADAP1 (centaurin-?1) in neuronal differentiation and neurodegenerative diseases, with an overview of structural and biochemical properties of ADAP1.
Stricker R, Reiser G
Biological chemistry395(11)1321-40(2014 Nov)

Retinoic acid-induced upregulation of the metalloendopeptidase nardilysin is accelerated by co-expression of the brain-specific protein p42(IP4) (centaurin ? 1; ADAP1) in neuroblastoma cells.
Borrmann C, Stricker R, Reiser G
Neurochemistry international59(6)936-44(2011 Nov)

Tubulin potentiates the interaction of the metalloendopeptidase nardilysin with the neuronal scaffold protein p42IP4/centaurin-?1 (ADAP1).
Borrmann C, Stricker R, Reiser G
Cell and tissue research346(1)89-98(2011 Oct)

Phosphorylation-independent dual-site binding of the FHA domain of KIF13 mediates phosphoinositide transport via centaurin alpha1.
Tong Y, Tempel W, Wang H, Yamada K, Shen L, Senisterra GA, MacKenzie F, Chishti AH, Park HW
Proceedings of the National Academy of Sciences of the United States of America107(47)20346-51(2010 Nov)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

This review highlights the functions of the neuron-specific protein ADAP1 in neuronal differentiation and neurodegenerative diseases, with an overview of structural and biochemical properties of ADAP1. [review]
Title: Functions of the neuron-specific protein ADAP1 (centaurin-?1) in neuronal differentiation and neurodegenerative diseases, with an overview of structural and biochemical properties of ADAP1.

SH-SY5Y cells, stably transfected with GFP-tagged-p42(IP4), show an enhanced NRD protein expression already at an earlier time point after retinoic acid stimulation.
Title: Retinoic acid-induced upregulation of the metalloendopeptidase nardilysin is accelerated by co-expression of the brain-specific protein p42(IP4) (centaurin ? 1; ADAP1) in neuroblastoma cells.

Tubulin potentiates the interaction of the metalloendopeptidase nardilysin with the neuronal scaffold protein p42IP4/centaurin-alpha1 (ADAP1).
Title: Tubulin potentiates the interaction of the metalloendopeptidase nardilysin with the neuronal scaffold protein p42IP4/centaurin-?1 (ADAP1).

Full-length KIF13B and CENTA1 form heterotetramers that can bind four phosphoinositide molecules in the vesicle and transport it along the microtubule.
Title: Phosphorylation-independent dual-site binding of the FHA domain of KIF13 mediates phosphoinositide transport via centaurin alpha1.

Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator)
Title: Polymorphisms in innate immunity genes and risk of childhood leukemia.

The following ADAP1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the ADAP1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu05326	NM_001284309.1 Latest version!	Homo sapiens ArfGAP with dual PH domains 1 (ADAP1), transcript variant 3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$99.50-$139.30 $199.00
OHu05326	NM_001284310.1 Latest version!	Homo sapiens ArfGAP with dual PH domains 1 (ADAP1), transcript variant 4, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$99.50-$139.30 $199.00
OHu05725	NM_006869.3 Latest version!	Homo sapiens ArfGAP with dual PH domains 1 (ADAP1), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
OHu05325	NM_001284308.1 Latest version!	Homo sapiens ArfGAP with dual PH domains 1 (ADAP1), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$223.30 $319.00
OHu05328	NM_001284311.1 Latest version!	Homo sapiens ArfGAP with dual PH domains 1 (ADAP1), transcript variant 5, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$139.30 $199.00
OHu107197	NM_006869.4 Latest version!	Homo sapiens ArfGAP with dual PH domains 1 (ADAP1), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$223.30 $319.00

ORF Online Only Promotion

Next-day Shipping ORF Clones ( in default vector with tag)
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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

ADAP1 ( NM_001284309.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001271238.1 Homo sapiens ArfGAP with dual PH domains 1 (ADAP1), transcript variant 3, mRNA.

Price & Availability↑

CloneID	OHu05326
Clone ID Related Accession (Same CDS sequence)	NM_001284309.1 , NM_001284310.1
Accession Version	NM_001284309.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 909bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-24
Organism	Homo sapiens(human)
Product	arf-GAP with dual PH domain-containing protein 1 isoform 3
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from DA872042.1, BC033747.1 and AI910700.1. On Sep 27, 2013 this sequence version replaced XM_005249588.1. Transcript Variant: This variant (3) contains an alternate 5' terminal exon and initiates translation from an in-frame downstream start codon compared to variant 1. The resulting isoform (3) has a shorter N-terminus compared to isoform 1. Variants 3 and 4 encode the same isoform. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## CDS exon combination :: SRR3476690.163816.1, SRR3476690.976394.1 [ECO:0000331] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGCCTCCC ACGGGAACGA CGCCGCGAGA GCCAGGTTTG AGTCCAAAGT ACCCTCCTTC 
TACTACCGGC CCACGCCCTC CGACTGCCAG CTCCTTCGAG AGCAGTGGAT CCGGGCCAAG 
TACGAGCGAC AGGAGTTCAT CTACCCGGAG AAGCAGGAGC CCTACTCGGC AGGGTACCGT 
GAGGGTTTTC TCTGGAAGCG TGGCCGGGAC AACGGGCAGT TTTTGAGCCG GAAGTTTGTG 
CTGACAGAAC GAGAGGGTGC TCTGAAGTAT TTCAACAGAA ATGATGCCAA GGAGCCCAAG 
GCCGTGATGA AGATCGAGCA CCTGAACGCC ACCTTCCAGC CGGCCAAGAT CGGCCACCCC 
CACGGCCTGC AGGTCACCTA CCTGAAGGAC AACAGCACCC GTAACATCTT CATCTACCAT 
GAGGACGGGA AGGAGATTGT GGACTGGTTC AATGCACTCC GAGCTGCTCG CTTCCACTAC 
CTGCAGGTGG CATTCCCAGG GGCCAGCGAC GCAGATCTGG TGCCAAAGCT CTCCAGGAAC 
TACCTGAAGG AAGGCTACAT GGAGAAGACG GGGCCCAAGC AAACGGAAGG CTTCCGGAAG 
CGCTGGTTCA CCATGGATGA CCGCAGGCTC ATGTACTTCA AAGACCCCCT GGACGCCTTC 
GCCCGAGGGG AAGTCTTCAT TGGCAGCAAG GAGAGTGGCT ACACGGTGCT GCATGGGTTC 
CCGCCGTCCA CCCAGGGCCA CCACTGGCCA CATGGCATCA CCATCGTCAC GCCCGACCGC 
AAGTTTCTGT TTGCCTGCGA GACGGAGTCC GACCAGAGGG AGTGGGTGGC GGCCTTCCAG 
AAGGCGGTGG ACAGGCCCAT GCTGCCCCAG GAGTACGCAG TGGAGGCGCA CTTCAAGCAT 
AAACCTTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001271238.1
CDS	190..1098
Translation	MASHGNDAARARFESKVPSFYYRPTPSDCQLLREQWIRAKYERQEFIYPEKQEPYSAGYREGFLWKRGRDNGQFLSRKFVLTEREGALKYFNRNDAKEPKAVMKIEHLNATFQPAKIGHPHGLQVTYLKDNSTRNIFIYHEDGKEIVDWFNALRAARFHYLQVAFPGASDADLVPKLSRNYLKEGYMEKTGPKQTEGFRKRWFTMDDRRLMYFKDPLDAFARGEVFIGSKESGYTVLHGFPPSTQGHHWPHGITIVTPDRKFLFACETESDQREWVAAFQKAVDRPMLPQEYAVEAHFKHKP

Target ORF information:

RefSeq Version	NM_001284309.1
Organism	Homo sapiens(human)
Definition	Homo sapiens ArfGAP with dual PH domains 1 (ADAP1), transcript variant 3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001284309.1

ORF Insert Sequence:

ATGGCCTCCC ACGGGAACGA CGCCGCGAGA GCCAGGTTTG AGTCCAAAGT ACCCTCCTTC 
TACTACCGGC CCACGCCCTC CGACTGCCAG CTCCTTCGAG AGCAGTGGAT CCGGGCCAAG 
TACGAGCGAC AGGAGTTCAT CTACCCGGAG AAGCAGGAGC CCTACTCGGC AGGGTACCGT 
GAGGGTTTTC TCTGGAAGCG TGGCCGGGAC AACGGGCAGT TTTTGAGCCG GAAGTTTGTG 
CTGACAGAAC GAGAGGGTGC TCTGAAGTAT TTCAACAGAA ATGATGCCAA GGAGCCCAAG 
GCCGTGATGA AGATCGAGCA CCTGAACGCC ACCTTCCAGC CGGCCAAGAT CGGCCACCCC 
CACGGCCTGC AGGTCACCTA CCTGAAGGAC AACAGCACCC GTAACATCTT CATCTACCAT 
GAGGACGGGA AGGAGATTGT GGACTGGTTC AATGCACTCC GAGCTGCTCG CTTCCACTAC 
CTGCAGGTGG CATTCCCAGG GGCCAGCGAC GCAGATCTGG TGCCAAAGCT CTCCAGGAAC 
TACCTGAAGG AAGGCTACAT GGAGAAGACG GGGCCCAAGC AAACGGAAGG CTTCCGGAAG 
CGCTGGTTCA CCATGGATGA CCGCAGGCTC ATGTACTTCA AAGACCCCCT GGACGCCTTC 
GCCCGAGGGG AAGTCTTCAT TGGCAGCAAG GAGAGTGGCT ACACGGTGCT GCATGGGTTC 
CCGCCGTCCA CCCAGGGCCA CCACTGGCCA CATGGCATCA CCATCGTCAC GCCCGACCGC 
AAGTTTCTGT TTGCCTGCGA GACGGAGTCC GACCAGAGGG AGTGGGTGGC GGCCTTCCAG 
AAGGCGGTGG ACAGGCCCAT GCTGCCCCAG GAGTACGCAG TGGAGGCGCA CTTCAAGCAT 
AAACCTTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

ADAP1 ( NM_001284310.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001271239.1 Homo sapiens ArfGAP with dual PH domains 1 (ADAP1), transcript variant 4, mRNA.

Price & Availability↑

CloneID	OHu05326
Clone ID Related Accession (Same CDS sequence)	NM_001284309.1 , NM_001284310.1
Accession Version	NM_001284310.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 909bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-24
Organism	Homo sapiens(human)
Product	arf-GAP with dual PH domain-containing protein 1 isoform 3
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AK092471.1, BC033747.1 and AI910700.1. On Sep 27, 2013 this sequence version replaced XM_005249589.1. Transcript Variant: This variant (4) lacks an exon at the 5' end and contains an alternate 5' terminal exon, which results in translation initiation from an in-frame downstream start codon compared to variant 1. The resulting isoform (3) has a shorter N-terminus compared to isoform 1. Variants 3 and 4 encode the same isoform. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK092471.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGCCTCCC ACGGGAACGA CGCCGCGAGA GCCAGGTTTG AGTCCAAAGT ACCCTCCTTC 
TACTACCGGC CCACGCCCTC CGACTGCCAG CTCCTTCGAG AGCAGTGGAT CCGGGCCAAG 
TACGAGCGAC AGGAGTTCAT CTACCCGGAG AAGCAGGAGC CCTACTCGGC AGGGTACCGT 
GAGGGTTTTC TCTGGAAGCG TGGCCGGGAC AACGGGCAGT TTTTGAGCCG GAAGTTTGTG 
CTGACAGAAC GAGAGGGTGC TCTGAAGTAT TTCAACAGAA ATGATGCCAA GGAGCCCAAG 
GCCGTGATGA AGATCGAGCA CCTGAACGCC ACCTTCCAGC CGGCCAAGAT CGGCCACCCC 
CACGGCCTGC AGGTCACCTA CCTGAAGGAC AACAGCACCC GTAACATCTT CATCTACCAT 
GAGGACGGGA AGGAGATTGT GGACTGGTTC AATGCACTCC GAGCTGCTCG CTTCCACTAC 
CTGCAGGTGG CATTCCCAGG GGCCAGCGAC GCAGATCTGG TGCCAAAGCT CTCCAGGAAC 
TACCTGAAGG AAGGCTACAT GGAGAAGACG GGGCCCAAGC AAACGGAAGG CTTCCGGAAG 
CGCTGGTTCA CCATGGATGA CCGCAGGCTC ATGTACTTCA AAGACCCCCT GGACGCCTTC 
GCCCGAGGGG AAGTCTTCAT TGGCAGCAAG GAGAGTGGCT ACACGGTGCT GCATGGGTTC 
CCGCCGTCCA CCCAGGGCCA CCACTGGCCA CATGGCATCA CCATCGTCAC GCCCGACCGC 
AAGTTTCTGT TTGCCTGCGA GACGGAGTCC GACCAGAGGG AGTGGGTGGC GGCCTTCCAG 
AAGGCGGTGG ACAGGCCCAT GCTGCCCCAG GAGTACGCAG TGGAGGCGCA CTTCAAGCAT 
AAACCTTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001271239.1
CDS	165..1073
Translation	MASHGNDAARARFESKVPSFYYRPTPSDCQLLREQWIRAKYERQEFIYPEKQEPYSAGYREGFLWKRGRDNGQFLSRKFVLTEREGALKYFNRNDAKEPKAVMKIEHLNATFQPAKIGHPHGLQVTYLKDNSTRNIFIYHEDGKEIVDWFNALRAARFHYLQVAFPGASDADLVPKLSRNYLKEGYMEKTGPKQTEGFRKRWFTMDDRRLMYFKDPLDAFARGEVFIGSKESGYTVLHGFPPSTQGHHWPHGITIVTPDRKFLFACETESDQREWVAAFQKAVDRPMLPQEYAVEAHFKHKP

Target ORF information:

RefSeq Version	NM_001284310.1
Organism	Homo sapiens(human)
Definition	Homo sapiens ArfGAP with dual PH domains 1 (ADAP1), transcript variant 4, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001284310.1

ORF Insert Sequence:

ATGGCCTCCC ACGGGAACGA CGCCGCGAGA GCCAGGTTTG AGTCCAAAGT ACCCTCCTTC 
TACTACCGGC CCACGCCCTC CGACTGCCAG CTCCTTCGAG AGCAGTGGAT CCGGGCCAAG 
TACGAGCGAC AGGAGTTCAT CTACCCGGAG AAGCAGGAGC CCTACTCGGC AGGGTACCGT 
GAGGGTTTTC TCTGGAAGCG TGGCCGGGAC AACGGGCAGT TTTTGAGCCG GAAGTTTGTG 
CTGACAGAAC GAGAGGGTGC TCTGAAGTAT TTCAACAGAA ATGATGCCAA GGAGCCCAAG 
GCCGTGATGA AGATCGAGCA CCTGAACGCC ACCTTCCAGC CGGCCAAGAT CGGCCACCCC 
CACGGCCTGC AGGTCACCTA CCTGAAGGAC AACAGCACCC GTAACATCTT CATCTACCAT 
GAGGACGGGA AGGAGATTGT GGACTGGTTC AATGCACTCC GAGCTGCTCG CTTCCACTAC 
CTGCAGGTGG CATTCCCAGG GGCCAGCGAC GCAGATCTGG TGCCAAAGCT CTCCAGGAAC 
TACCTGAAGG AAGGCTACAT GGAGAAGACG GGGCCCAAGC AAACGGAAGG CTTCCGGAAG 
CGCTGGTTCA CCATGGATGA CCGCAGGCTC ATGTACTTCA AAGACCCCCT GGACGCCTTC 
GCCCGAGGGG AAGTCTTCAT TGGCAGCAAG GAGAGTGGCT ACACGGTGCT GCATGGGTTC 
CCGCCGTCCA CCCAGGGCCA CCACTGGCCA CATGGCATCA CCATCGTCAC GCCCGACCGC 
AAGTTTCTGT TTGCCTGCGA GACGGAGTCC GACCAGAGGG AGTGGGTGGC GGCCTTCCAG 
AAGGCGGTGG ACAGGCCCAT GCTGCCCCAG GAGTACGCAG TGGAGGCGCA CTTCAAGCAT 
AAACCTTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

ADAP1 ( NM_006869.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_006860.1 Homo sapiens ArfGAP with dual PH domains 1 (ADAP1), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu05725
Clone ID Related Accession (Same CDS sequence)	NM_006869.3
Accession Version	NM_006869.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1125bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-10-02
Organism	Homo sapiens(human)
Product	arf-GAP with dual PH domain-containing protein 1 isoform 1
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BG716328.1, CR975507.1, BC033747.1 and AI910700.1. On Sep 27, 2013 this sequence version replaced NM_006869.2. Transcript Variant: This variant (1) represents the predominant transcript and encodes isoform 1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1163655.31505.1, AB097049.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGCCAAGG AGCGGCGCAG GGCGGTCCTG GAGCTGCTGC AGCGGCCGGG GAACGCGCGC 
TGCGCGGACT GCGGCGCCCC GGATCCCGAC TGGGCCTCCT ACACTCTGGG CGTCTTCATC 
TGCCTGAGCT GCTCGGGAAT CCACCGGAAT ATCCCCCAGG TCAGCAAGGT GAAGTCCGTC 
CGCCTGGACG CCTGGGAGGA GGCCCAAGTG GAGTTCATGG CCTCCCACGG GAACGACGCC 
GCGAGAGCCA GGTTTGAGTC CAAAGTACCC TCCTTCTACT ACCGGCCCAC GCCCTCCGAC 
TGCCAGCTCC TTCGAGAGCA GTGGATCCGG GCCAAGTACG AGCGACAGGA GTTCATCTAC 
CCGGAGAAGC AGGAGCCCTA CTCGGCAGGG TACCGTGAGG GTTTTCTCTG GAAGCGTGGC 
CGGGACAACG GGCAGTTTTT GAGCCGGAAG TTTGTGCTGA CAGAACGAGA GGGTGCTCTG 
AAGTATTTCA ACAGAAATGA TGCCAAGGAG CCCAAGGCCG TGATGAAGAT CGAGCACCTG 
AACGCCACCT TCCAGCCGGC CAAGATCGGC CACCCCCACG GCCTGCAGGT CACCTACCTG 
AAGGACAACA GCACCCGTAA CATCTTCATC TACCATGAGG ACGGGAAGGA GATTGTGGAC 
TGGTTCAATG CACTCCGAGC TGCTCGCTTC CACTACCTGC AGGTGGCATT CCCAGGGGCC 
AGCGACGCAG ATCTGGTGCC AAAGCTCTCC AGGAACTACC TGAAGGAAGG CTACATGGAG 
AAGACGGGGC CCAAGCAAAC GGAAGGCTTC CGGAAGCGCT GGTTCACCAT GGATGACCGC 
AGGCTCATGT ACTTCAAAGA CCCCCTGGAC GCCTTCGCCC GAGGGGAAGT CTTCATTGGC 
AGCAAGGAGA GTGGCTACAC GGTGCTGCAT GGGTTCCCGC CGTCCACCCA GGGCCACCAC 
TGGCCACATG GCATCACCAT CGTCACGCCC GACCGCAAGT TTCTGTTTGC CTGCGAGACG 
GAGTCCGACC AGAGGGAGTG GGTGGCGGCC TTCCAGAAGG CGGTGGACAG GCCCATGCTG 
CCCCAGGAGT ACGCAGTGGA GGCGCACTTC AAGCATAAAC CTTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_006860.1
CDS	207..1331
Translation	MAKERRRAVLELLQRPGNARCADCGAPDPDWASYTLGVFICLSCSGIHRNIPQVSKVKSVRLDAWEEAQVEFMASHGNDAARARFESKVPSFYYRPTPSDCQLLREQWIRAKYERQEFIYPEKQEPYSAGYREGFLWKRGRDNGQFLSRKFVLTEREGALKYFNRNDAKEPKAVMKIEHLNATFQPAKIGHPHGLQVTYLKDNSTRNIFIYHEDGKEIVDWFNALRAARFHYLQVAFPGASDADLVPKLSRNYLKEGYMEKTGPKQTEGFRKRWFTMDDRRLMYFKDPLDAFARGEVFIGSKESGYTVLHGFPPSTQGHHWPHGITIVTPDRKFLFACETESDQREWVAAFQKAVDRPMLPQEYAVEAHFKHKP

Target ORF information:

RefSeq Version	NM_006869.3
Organism	Homo sapiens(human)
Definition	Homo sapiens ArfGAP with dual PH domains 1 (ADAP1), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_006869.3

ORF Insert Sequence:

ATGGCCAAGG AGCGGCGCAG GGCGGTCCTG GAGCTGCTGC AGCGGCCGGG GAACGCGCGC 
TGCGCGGACT GCGGCGCCCC GGATCCCGAC TGGGCCTCCT ACACTCTGGG CGTCTTCATC 
TGCCTGAGCT GCTCGGGAAT CCACCGGAAT ATCCCCCAGG TCAGCAAGGT GAAGTCCGTC 
CGCCTGGACG CCTGGGAGGA GGCCCAAGTG GAGTTCATGG CCTCCCACGG GAACGACGCC 
GCGAGAGCCA GGTTTGAGTC CAAAGTACCC TCCTTCTACT ACCGGCCCAC GCCCTCCGAC 
TGCCAGCTCC TTCGAGAGCA GTGGATCCGG GCCAAGTACG AGCGACAGGA GTTCATCTAC 
CCGGAGAAGC AGGAGCCCTA CTCGGCAGGG TACCGTGAGG GTTTTCTCTG GAAGCGTGGC 
CGGGACAACG GGCAGTTTTT GAGCCGGAAG TTTGTGCTGA CAGAACGAGA GGGTGCTCTG 
AAGTATTTCA ACAGAAATGA TGCCAAGGAG CCCAAGGCCG TGATGAAGAT CGAGCACCTG 
AACGCCACCT TCCAGCCGGC CAAGATCGGC CACCCCCACG GCCTGCAGGT CACCTACCTG 
AAGGACAACA GCACCCGTAA CATCTTCATC TACCATGAGG ACGGGAAGGA GATTGTGGAC 
TGGTTCAATG CACTCCGAGC TGCTCGCTTC CACTACCTGC AGGTGGCATT CCCAGGGGCC 
AGCGACGCAG ATCTGGTGCC AAAGCTCTCC AGGAACTACC TGAAGGAAGG CTACATGGAG 
AAGACGGGGC CCAAGCAAAC GGAAGGCTTC CGGAAGCGCT GGTTCACCAT GGATGACCGC 
AGGCTCATGT ACTTCAAAGA CCCCCTGGAC GCCTTCGCCC GAGGGGAAGT CTTCATTGGC 
AGCAAGGAGA GTGGCTACAC GGTGCTGCAT GGGTTCCCGC CGTCCACCCA GGGCCACCAC 
TGGCCACATG GCATCACCAT CGTCACGCCC GACCGCAAGT TTCTGTTTGC CTGCGAGACG 
GAGTCCGACC AGAGGGAGTG GGTGGCGGCC TTCCAGAAGG CGGTGGACAG GCCCATGCTG 
CCCCAGGAGT ACGCAGTGGA GGCGCACTTC AAGCATAAAC CTTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

ADAP1 ( NM_001284308.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001271237.1 Homo sapiens ArfGAP with dual PH domains 1 (ADAP1), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu05325
Clone ID Related Accession (Same CDS sequence)	NM_001284308.1
Accession Version	NM_001284308.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1158bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-24
Organism	Homo sapiens(human)
Product	arf-GAP with dual PH domain-containing protein 1 isoform 2
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AK300999.1, BC033747.1 and AI910700.1. On Sep 27, 2013 this sequence version replaced XM_005249586.1. Transcript Variant: This variant (2) contains an alternate 5' terminal exon and initiates translation from an alternate upstream start codon compared to variant 1. The resulting longer isoform (2) has a distinct N-terminus compared to isoform 1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK300999.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGTTCCAGT TTGTTTTCAG CCGGGTGTAC TGCATTAACC CTGCAAGAAG AAAATGGAAA 
GAATTTGAAA AGATGCTGGG GTGTGCAGAG GAAGGGCACG CGAGTCTGGG AAGAGATCCC 
GACTGGGCCT CCTACACTCT GGGCGTCTTC ATCTGCCTGA GCTGCTCGGG AATCCACCGG 
AATATCCCCC AGGTCAGCAA GGTGAAGTCC GTCCGCCTGG ACGCCTGGGA GGAGGCCCAA 
GTGGAGTTCA TGGCCTCCCA CGGGAACGAC GCCGCGAGAG CCAGGTTTGA GTCCAAAGTA 
CCCTCCTTCT ACTACCGGCC CACGCCCTCC GACTGCCAGC TCCTTCGAGA GCAGTGGATC 
CGGGCCAAGT ACGAGCGACA GGAGTTCATC TACCCGGAGA AGCAGGAGCC CTACTCGGCA 
GGGTACCGTG AGGGTTTTCT CTGGAAGCGT GGCCGGGACA ACGGGCAGTT TTTGAGCCGG 
AAGTTTGTGC TGACAGAACG AGAGGGTGCT CTGAAGTATT TCAACAGAAA TGATGCCAAG 
GAGCCCAAGG CCGTGATGAA GATCGAGCAC CTGAACGCCA CCTTCCAGCC GGCCAAGATC 
GGCCACCCCC ACGGCCTGCA GGTCACCTAC CTGAAGGACA ACAGCACCCG TAACATCTTC 
ATCTACCATG AGGACGGGAA GGAGATTGTG GACTGGTTCA ATGCACTCCG AGCTGCTCGC 
TTCCACTACC TGCAGGTGGC ATTCCCAGGG GCCAGCGACG CAGATCTGGT GCCAAAGCTC 
TCCAGGAACT ACCTGAAGGA AGGCTACATG GAGAAGACGG GGCCCAAGCA AACGGAAGGC 
TTCCGGAAGC GCTGGTTCAC CATGGATGAC CGCAGGCTCA TGTACTTCAA AGACCCCCTG 
GACGCCTTCG CCCGAGGGGA AGTCTTCATT GGCAGCAAGG AGAGTGGCTA CACGGTGCTG 
CATGGGTTCC CGCCGTCCAC CCAGGGCCAC CACTGGCCAC ATGGCATCAC CATCGTCACG 
CCCGACCGCA AGTTTCTGTT TGCCTGCGAG ACGGAGTCCG ACCAGAGGGA GTGGGTGGCG 
GCCTTCCAGA AGGCGGTGGA CAGGCCCATG CTGCCCCAGG AGTACGCAGT GGAGGCGCAC 
TTCAAGCATA AACCTTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001271237.1
CDS	1..1158
Translation	MFQFVFSRVYCINPARRKWKEFEKMLGCAEEGHASLGRDPDWASYTLGVFICLSCSGIHRNIPQVSKVKSVRLDAWEEAQVEFMASHGNDAARARFESKVPSFYYRPTPSDCQLLREQWIRAKYERQEFIYPEKQEPYSAGYREGFLWKRGRDNGQFLSRKFVLTEREGALKYFNRNDAKEPKAVMKIEHLNATFQPAKIGHPHGLQVTYLKDNSTRNIFIYHEDGKEIVDWFNALRAARFHYLQVAFPGASDADLVPKLSRNYLKEGYMEKTGPKQTEGFRKRWFTMDDRRLMYFKDPLDAFARGEVFIGSKESGYTVLHGFPPSTQGHHWPHGITIVTPDRKFLFACETESDQREWVAAFQKAVDRPMLPQEYAVEAHFKHKP

Target ORF information:

RefSeq Version	NM_001284308.1
Organism	Homo sapiens(human)
Definition	Homo sapiens ArfGAP with dual PH domains 1 (ADAP1), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001284308.1

ORF Insert Sequence:

ATGTTCCAGT TTGTTTTCAG CCGGGTGTAC TGCATTAACC CTGCAAGAAG AAAATGGAAA 
GAATTTGAAA AGATGCTGGG GTGTGCAGAG GAAGGGCACG CGAGTCTGGG AAGAGATCCC 
GACTGGGCCT CCTACACTCT GGGCGTCTTC ATCTGCCTGA GCTGCTCGGG AATCCACCGG 
AATATCCCCC AGGTCAGCAA GGTGAAGTCC GTCCGCCTGG ACGCCTGGGA GGAGGCCCAA 
GTGGAGTTCA TGGCCTCCCA CGGGAACGAC GCCGCGAGAG CCAGGTTTGA GTCCAAAGTA 
CCCTCCTTCT ACTACCGGCC CACGCCCTCC GACTGCCAGC TCCTTCGAGA GCAGTGGATC 
CGGGCCAAGT ACGAGCGACA GGAGTTCATC TACCCGGAGA AGCAGGAGCC CTACTCGGCA 
GGGTACCGTG AGGGTTTTCT CTGGAAGCGT GGCCGGGACA ACGGGCAGTT TTTGAGCCGG 
AAGTTTGTGC TGACAGAACG AGAGGGTGCT CTGAAGTATT TCAACAGAAA TGATGCCAAG 
GAGCCCAAGG CCGTGATGAA GATCGAGCAC CTGAACGCCA CCTTCCAGCC GGCCAAGATC 
GGCCACCCCC ACGGCCTGCA GGTCACCTAC CTGAAGGACA ACAGCACCCG TAACATCTTC 
ATCTACCATG AGGACGGGAA GGAGATTGTG GACTGGTTCA ATGCACTCCG AGCTGCTCGC 
TTCCACTACC TGCAGGTGGC ATTCCCAGGG GCCAGCGACG CAGATCTGGT GCCAAAGCTC 
TCCAGGAACT ACCTGAAGGA AGGCTACATG GAGAAGACGG GGCCCAAGCA AACGGAAGGC 
TTCCGGAAGC GCTGGTTCAC CATGGATGAC CGCAGGCTCA TGTACTTCAA AGACCCCCTG 
GACGCCTTCG CCCGAGGGGA AGTCTTCATT GGCAGCAAGG AGAGTGGCTA CACGGTGCTG 
CATGGGTTCC CGCCGTCCAC CCAGGGCCAC CACTGGCCAC ATGGCATCAC CATCGTCACG 
CCCGACCGCA AGTTTCTGTT TGCCTGCGAG ACGGAGTCCG ACCAGAGGGA GTGGGTGGCG 
GCCTTCCAGA AGGCGGTGGA CAGGCCCATG CTGCCCCAGG AGTACGCAGT GGAGGCGCAC 
TTCAAGCATA AACCTTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

ADAP1 ( NM_001284311.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001271240.1 Homo sapiens ArfGAP with dual PH domains 1 (ADAP1), transcript variant 5, mRNA.

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CloneID	OHu05328
Clone ID Related Accession (Same CDS sequence)	NM_001284311.1
Accession Version	NM_001284311.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 840bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-22
Organism	Homo sapiens(human)
Product	arf-GAP with dual PH domain-containing protein 1 isoform 4
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BM837987.1, AK300859.1, BC033747.1 and AI910700.1. On Sep 27, 2013 this sequence version replaced XM_005249590.1. Transcript Variant: This variant (5) lacks 2 exons at the 5' end and contains an alternate 5' terminal exon, which results in translation initiation from an alternate start codon compared to variant 1. The resulting shorter isoform (4) has a distinct N-terminus compared to isoform 1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK300859.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGTATTGG CTTCACTCGA GCTCCTTCGA GAGCAGTGGA TCCGGGCCAA GTACGAGCGA 
CAGGAGTTCA TCTACCCGGA GAAGCAGGAG CCCTACTCGG CAGGGTACCG TGAGGGTTTT 
CTCTGGAAGC GTGGCCGGGA CAACGGGCAG TTTTTGAGCC GGAAGTTTGT GCTGACAGAA 
CGAGAGGGTG CTCTGAAGTA TTTCAACAGA AATGATGCCA AGGAGCCCAA GGCCGTGATG 
AAGATCGAGC ACCTGAACGC CACCTTCCAG CCGGCCAAGA TCGGCCACCC CCACGGCCTG 
CAGGTCACCT ACCTGAAGGA CAACAGCACC CGTAACATCT TCATCTACCA TGAGGACGGG 
AAGGAGATTG TGGACTGGTT CAATGCACTC CGAGCTGCTC GCTTCCACTA CCTGCAGGTG 
GCATTCCCAG GGGCCAGCGA CGCAGATCTG GTGCCAAAGC TCTCCAGGAA CTACCTGAAG 
GAAGGCTACA TGGAGAAGAC GGGGCCCAAG CAAACGGAAG GCTTCCGGAA GCGCTGGTTC 
ACCATGGATG ACCGCAGGCT CATGTACTTC AAAGACCCCC TGGACGCCTT CGCCCGAGGG 
GAAGTCTTCA TTGGCAGCAA GGAGAGTGGC TACACGGTGC TGCATGGGTT CCCGCCGTCC 
ACCCAGGGCC ACCACTGGCC ACATGGCATC ACCATCGTCA CGCCCGACCG CAAGTTTCTG 
TTTGCCTGCG AGACGGAGTC CGACCAGAGG GAGTGGGTGG CGGCCTTCCA GAAGGCGGTG 
GACAGGCCCA TGCTGCCCCA GGAGTACGCA GTGGAGGCGC ACTTCAAGCA TAAACCTTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001271240.1
CDS	87..926
Translation	MVLASLELLREQWIRAKYERQEFIYPEKQEPYSAGYREGFLWKRGRDNGQFLSRKFVLTEREGALKYFNRNDAKEPKAVMKIEHLNATFQPAKIGHPHGLQVTYLKDNSTRNIFIYHEDGKEIVDWFNALRAARFHYLQVAFPGASDADLVPKLSRNYLKEGYMEKTGPKQTEGFRKRWFTMDDRRLMYFKDPLDAFARGEVFIGSKESGYTVLHGFPPSTQGHHWPHGITIVTPDRKFLFACETESDQREWVAAFQKAVDRPMLPQEYAVEAHFKHKP

Target ORF information:

RefSeq Version	NM_001284311.1
Organism	Homo sapiens(human)
Definition	Homo sapiens ArfGAP with dual PH domains 1 (ADAP1), transcript variant 5, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001284311.1

ORF Insert Sequence:

ATGGTATTGG CTTCACTCGA GCTCCTTCGA GAGCAGTGGA TCCGGGCCAA GTACGAGCGA 
CAGGAGTTCA TCTACCCGGA GAAGCAGGAG CCCTACTCGG CAGGGTACCG TGAGGGTTTT 
CTCTGGAAGC GTGGCCGGGA CAACGGGCAG TTTTTGAGCC GGAAGTTTGT GCTGACAGAA 
CGAGAGGGTG CTCTGAAGTA TTTCAACAGA AATGATGCCA AGGAGCCCAA GGCCGTGATG 
AAGATCGAGC ACCTGAACGC CACCTTCCAG CCGGCCAAGA TCGGCCACCC CCACGGCCTG 
CAGGTCACCT ACCTGAAGGA CAACAGCACC CGTAACATCT TCATCTACCA TGAGGACGGG 
AAGGAGATTG TGGACTGGTT CAATGCACTC CGAGCTGCTC GCTTCCACTA CCTGCAGGTG 
GCATTCCCAG GGGCCAGCGA CGCAGATCTG GTGCCAAAGC TCTCCAGGAA CTACCTGAAG 
GAAGGCTACA TGGAGAAGAC GGGGCCCAAG CAAACGGAAG GCTTCCGGAA GCGCTGGTTC 
ACCATGGATG ACCGCAGGCT CATGTACTTC AAAGACCCCC TGGACGCCTT CGCCCGAGGG 
GAAGTCTTCA TTGGCAGCAA GGAGAGTGGC TACACGGTGC TGCATGGGTT CCCGCCGTCC 
ACCCAGGGCC ACCACTGGCC ACATGGCATC ACCATCGTCA CGCCCGACCG CAAGTTTCTG 
TTTGCCTGCG AGACGGAGTC CGACCAGAGG GAGTGGGTGG CGGCCTTCCA GAAGGCGGTG 
GACAGGCCCA TGCTGCCCCA GGAGTACGCA GTGGAGGCGC ACTTCAAGCA TAAACCTTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

ADAP1 ( NM_006869.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_006860.2 Homo sapiens ArfGAP with dual PH domains 1 (ADAP1), transcript variant 1, mRNA.

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CloneID	OHu107197
Clone ID Related Accession (Same CDS sequence)	NM_006869.4
Accession Version	NM_006869.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1125bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2020-01-01
Organism	Homo sapiens(human)
Product	arf-GAP with dual PH domain-containing protein 1 isoform 1
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC073957.7. On Nov 23, 2018 this sequence version replaced NM_006869.3. Transcript Variant: This variant (1) represents the predominant transcript and encodes isoform 1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1163655.31505.1, AB097049.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000265846.10/ ENSP00000265846.5 RefSeq Select criteria :: based on conservation, expression ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGGCCAAGG AGCGGCGCAG GGCGGTCCTG GAGCTGCTGC AGCGGCCGGG GAACGCGCGC 
TGCGCGGACT GCGGCGCCCC GGATCCCGAC TGGGCCTCCT ACACTCTGGG CGTCTTCATC 
TGCCTGAGCT GCTCGGGAAT CCACCGGAAT ATCCCCCAGG TCAGCAAGGT GAAGTCCGTC 
CGCCTGGACG CCTGGGAGGA GGCCCAAGTG GAGTTCATGG CCTCCCACGG GAACGACGCC 
GCGAGAGCCA GGTTTGAGTC CAAAGTACCC TCCTTCTACT ACCGGCCCAC GCCCTCCGAC 
TGCCAGCTCC TTCGAGAGCA GTGGATCCGG GCCAAGTACG AGCGACAGGA GTTCATCTAC 
CCGGAGAAGC AGGAGCCCTA CTCGGCAGGG TACCGTGAGG GTTTTCTCTG GAAGCGTGGC 
CGGGACAACG GGCAGTTTTT GAGCCGGAAG TTTGTGCTGA CAGAACGAGA GGGTGCTCTG 
AAGTATTTCA ACAGAAATGA TGCCAAGGAG CCCAAGGCCG TGATGAAGAT CGAGCACCTG 
AACGCCACCT TCCAGCCGGC CAAGATCGGC CACCCCCACG GCCTGCAGGT CACCTACCTG 
AAGGACAACA GCACCCGTAA CATCTTCATC TACCATGAGG ACGGGAAGGA GATTGTGGAC 
TGGTTCAATG CACTCCGAGC TGCTCGCTTC CACTACCTGC AGGTGGCATT CCCAGGGGCC 
GGCGACGCAG ATCTGGTGCC AAAGCTCTCC AGGAACTACC TGAAGGAAGG CTACATGGAG 
AAGACGGGGC CCAAGCAAAC GGAAGGCTTC CGGAAGCGCT GGTTCACCAT GGATGACCGC 
AGGCTCATGT ACTTCAAAGA CCCCCTGGAC GCCTTCGCCC GAGGGGAAGT CTTCATTGGC 
AGCAAGGAGA GTGGCTACAC GGTGCTGCAT GGGTTCCCGC CGTCCACCCA GGGCCACCAC 
TGGCCACATG GCATCACCAT CGTCACGCCC GACCGCAAGT TTCTGTTTGC CTGCGAGACG 
GAGTCCGACC AGAGGGAGTG GGTGGCGGCC TTCCAGAAGG CGGTGGACAG GCCCATGCTG 
CCCCAGGAGT ACGCAGTGGA GGCGCACTTC AAGCATAAAC CTTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_006860.2
CDS	204..1328
Translation	MAKERRRAVLELLQRPGNARCADCGAPDPDWASYTLGVFICLSCSGIHRNIPQVSKVKSVRLDAWEEAQVEFMASHGNDAARARFESKVPSFYYRPTPSDCQLLREQWIRAKYERQEFIYPEKQEPYSAGYREGFLWKRGRDNGQFLSRKFVLTEREGALKYFNRNDAKEPKAVMKIEHLNATFQPAKIGHPHGLQVTYLKDNSTRNIFIYHEDGKEIVDWFNALRAARFHYLQVAFPGAGDADLVPKLSRNYLKEGYMEKTGPKQTEGFRKRWFTMDDRRLMYFKDPLDAFARGEVFIGSKESGYTVLHGFPPSTQGHHWPHGITIVTPDRKFLFACETESDQREWVAAFQKAVDRPMLPQEYAVEAHFKHKP

Target ORF information:

RefSeq Version	NM_006869.4
Organism	Homo sapiens(human)
Definition	Homo sapiens ArfGAP with dual PH domains 1 (ADAP1), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_006869.4

ORF Insert Sequence:

ATGGCCAAGG AGCGGCGCAG GGCGGTCCTG GAGCTGCTGC AGCGGCCGGG GAACGCGCGC 
TGCGCGGACT GCGGCGCCCC GGATCCCGAC TGGGCCTCCT ACACTCTGGG CGTCTTCATC 
TGCCTGAGCT GCTCGGGAAT CCACCGGAAT ATCCCCCAGG TCAGCAAGGT GAAGTCCGTC 
CGCCTGGACG CCTGGGAGGA GGCCCAAGTG GAGTTCATGG CCTCCCACGG GAACGACGCC 
GCGAGAGCCA GGTTTGAGTC CAAAGTACCC TCCTTCTACT ACCGGCCCAC GCCCTCCGAC 
TGCCAGCTCC TTCGAGAGCA GTGGATCCGG GCCAAGTACG AGCGACAGGA GTTCATCTAC 
CCGGAGAAGC AGGAGCCCTA CTCGGCAGGG TACCGTGAGG GTTTTCTCTG GAAGCGTGGC 
CGGGACAACG GGCAGTTTTT GAGCCGGAAG TTTGTGCTGA CAGAACGAGA GGGTGCTCTG 
AAGTATTTCA ACAGAAATGA TGCCAAGGAG CCCAAGGCCG TGATGAAGAT CGAGCACCTG 
AACGCCACCT TCCAGCCGGC CAAGATCGGC CACCCCCACG GCCTGCAGGT CACCTACCTG 
AAGGACAACA GCACCCGTAA CATCTTCATC TACCATGAGG ACGGGAAGGA GATTGTGGAC 
TGGTTCAATG CACTCCGAGC TGCTCGCTTC CACTACCTGC AGGTGGCATT CCCAGGGGCC 
GGCGACGCAG ATCTGGTGCC AAAGCTCTCC AGGAACTACC TGAAGGAAGG CTACATGGAG 
AAGACGGGGC CCAAGCAAAC GGAAGGCTTC CGGAAGCGCT GGTTCACCAT GGATGACCGC 
AGGCTCATGT ACTTCAAAGA CCCCCTGGAC GCCTTCGCCC GAGGGGAAGT CTTCATTGGC 
AGCAAGGAGA GTGGCTACAC GGTGCTGCAT GGGTTCCCGC CGTCCACCCA GGGCCACCAC 
TGGCCACATG GCATCACCAT CGTCACGCCC GACCGCAAGT TTCTGTTTGC CTGCGAGACG 
GAGTCCGACC AGAGGGAGTG GGTGGCGGCC TTCCAGAAGG CGGTGGACAG GCCCATGCTG 
CCCCAGGAGT ACGCAGTGGA GGCGCACTTC AAGCATAAAC CTTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Functions of the neuron-specific protein ADAP1 (centaurin-?1) in neuronal differentiation and neurodegenerative diseases, with an overview of structural and biochemical properties of ADAP1.
Biological chemistry395(11)1321-40(2014 Nov)
Stricker R,Reiser G

Retinoic acid-induced upregulation of the metalloendopeptidase nardilysin is accelerated by co-expression of the brain-specific protein p42(IP4) (centaurin ? 1; ADAP1) in neuroblastoma cells.
Neurochemistry international59(6)936-44(2011 Nov)
Borrmann C,Stricker R,Reiser G

Tubulin potentiates the interaction of the metalloendopeptidase nardilysin with the neuronal scaffold protein p42IP4/centaurin-?1 (ADAP1).
Cell and tissue research346(1)89-98(2011 Oct)
Borrmann C,Stricker R,Reiser G

Phosphorylation-independent dual-site binding of the FHA domain of KIF13 mediates phosphoinositide transport via centaurin alpha1.
Proceedings of the National Academy of Sciences of the United States of America107(47)20346-51(2010 Nov)
Tong Y,Tempel W,Wang H,Yamada K,Shen L,Senisterra GA,MacKenzie F,Chishti AH,Park HW

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ADAP1 cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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