MAPRE2 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	MAPRE2
Entrez Gene ID	10982
Full Name	microtubule associated protein RP/EB family member 2
Synonyms	CSCSC2,EB1,EB2,RP1
General protein information	Preferred Names microtubule associated protein RP/EB family member 2 Names microtubule-associated protein RP/EB family member 2 APC-binding protein EB1 APC-binding protein EB2 T-cell activation protein, EB1 family end-binding protein 2
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 18 Map Location: 18q12.1-q12.2
Summary	The protein encoded by this gene shares significant homology to the adenomatous polyposis coli (APC) protein-binding EB1 gene family. This protein is a microtubule-associated protein that is necessary for spindle symmetry during mitosis. It is thought to play a role in the tumorigenesis of colorectal cancers and the proliferative control of normal cells. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Jan 2012].
Disorder MIM:	605789
Disorder Html:	Symmetric circumferential skin creases, congenital, 2, 616734 (3)

mRNA and Protein(s)

mRNA	Protein	Name
NM_001256420.2	NP_001243349.1	microtubule-associated protein RP/EB family member 2 isoform 4
NM_001143827.3	NP_001137299.1	microtubule-associated protein RP/EB family member 2 isoform 3
NM_014268.3	NP_055083.1	microtubule-associated protein RP/EB family member 2 isoform 1
NM_001143827.2	NP_001137299.1	microtubule-associated protein RP/EB family member 2 isoform 3
NM_001256420.1	NP_001243349.1	microtubule-associated protein RP/EB family member 2 isoform 4
NM_001143826.2	NP_001137298.1	microtubule-associated protein RP/EB family member 2 isoform 2
NM_014268.4	NP_055083.1	microtubule-associated protein RP/EB family member 2 isoform 1

Pathways from BioSystems

Homologies

Homo sapiens (human)	MAPRE2	NP_055083.1
Gallus gallus (chicken)	MAPRE2	NP_001026188.1
	MAPRE2	XP_001103596.1
Pan troglodytes (chimpanzee)	MAPRE2	XP_003315904.1
Canis lupus familiaris (dog)	MAPRE2	XP_005622940.1

Gene Ontology
Bibliography

Related articles in PubMed

Architecture of the human interactome defines protein communities and disease networks.
Huttlin EL, Bruckner RJ, Paulo JA, Cannon JR, Ting L, Baltier K, Colby G, Gebreab F, Gygi MP, Parzen H, Szpyt J, Tam S, Zarraga G, Pontano-Vaites L, Swarup S, White AE, Schweppe DK, Rad R, Erickson BK, Obar RA, Guruharsha KG, Li K, Artavanis-Tsakonas S, Gygi SP, Harper JW
Nature545(7655)505-509(2017 05)

An organelle-specific protein landscape identifies novel diseases and molecular mechanisms.
Boldt K, van Reeuwijk J, Lu Q, Koutroumpas K, Nguyen TM, Texier Y, van Beersum SE, Horn N, Willer JR, Mans DA, Dougherty G, Lamers IJ, Coene KL, Arts HH, Betts MJ, Beyer T, Bolat E, Gloeckner CJ, Haidari K, Hetterschijt L, Iaconis D, Jenkins D, Klose F, Knapp B, Latour B, Letteboer SJ, Marcelis CL, Mitic D, Morleo M, Oud MM, Riemersma M, Rix S, Terhal PA, Toedt G, van Dam TJ, de Vrieze E, Wissinger Y, Wu KM, Apic G, Beales PL, Blacque OE, Gibson TJ, Huynen MA, Katsanis N, Kremer H, Omran H, van Wijk E, Wolfrum U, Kepes F, Davis EE, Franco B, Giles RH, Ueffing M, Russell RB, Roepman R,
Nature communications711491(2016 May)

Pooled-matrix protein interaction screens using Barcode Fusion Genetics.
Yachie N, Petsalaki E, Mellor JC, Weile J, Jacob Y, Verby M, Ozturk SB, Li S, Cote AG, Mosca R, Knapp JJ, Ko M, Yu A, Gebbia M, Sahni N, Yi S, Tyagi T, Sheykhkarimli D, Roth JF, Wong C, Musa L, Snider J, Liu YC, Yu H, Braun P, Stagljar I, Hao T, Calderwood MA, Pelletier L, Aloy P, Hill DE, Vidal M, Roth FP
Molecular systems biology12(4)863(2016 Apr)

Phosphorylation of EB2 by Aurora B and CDK1 ensures mitotic progression and genome stability.
Iimori M, Watanabe S, Kiyonari S, Matsuoka K, Sakasai R, Saeki H, Oki E, Kitao H, Maehara Y
Nature communications711117(2016 Mar)

Mutations in Either TUBB or MAPRE2 Cause Circumferential Skin Creases Kunze Type.
Isrie M, Breuss M, Tian G, Hansen AH, Cristofoli F, Morandell J, Kupchinsky ZA, Sifrim A, Rodriguez-Rodriguez CM, Dapena EP, Doonanco K, Leonard N, Tinsa F, Moortgat S, Ulucan H, Koparir E, Karaca E, Katsanis N, Marton V, Vermeesch JR, Davis EE, Cowan NJ, Keays DA, Van Esch H
American journal of human genetics97(6)790-800(2015 Dec)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Aurora B and CDK1 temporally regulate the binding affinity of EB2 for microtubules, thereby ensuring kinetochore microtubule dynamics, proper mitotic progression and genome stability.
Title: Phosphorylation of EB2 by Aurora B and CDK1 ensures mitotic progression and genome stability.

Mutations in either TUBB or MAPRE2 cause circumferential skin creases Kunze type.
Title: Mutations in Either TUBB or MAPRE2 Cause Circumferential Skin Creases Kunze Type.

EB2 is evidently important for initial microtubule reorganisation during epithelial polarisation, whereas its downregulation facilitates EB1 and ACF7 microtubule lattice association, microtubule-actin filament co-alignment and bundle formation.
Title: The microtubule end-binding protein EB2 is a central regulator of microtubule reorganisation in apico-basal epithelial differentiation.

results suggest that EB1 and ClipCG12 act cooperatively to regulate microtubule dynamics (EB1)
Title: Cooperative stabilization of microtubule dynamics by EB1 and CLIP-170 involves displacement of stably bound P(i) at microtubule ends.

Clinical trial of gene-disease association and gene-environment interaction. (HuGE Navigator)
Title: Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.

The following MAPRE2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the MAPRE2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu21066	NM_014268.4 Latest version!	Homo sapiens microtubule associated protein RP/EB family member 2 (MAPRE2), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$99.50-$139.30 $199.00
OHu20780	NM_001143826.2 Latest version!	Homo sapiens microtubule associated protein RP/EB family member 2 (MAPRE2), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$139.30 $199.00
OHu21207	NM_001256420.2 Latest version!	Homo sapiens microtubule associated protein RP/EB family member 2 (MAPRE2), transcript variant 4, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$139.30 $199.00
OHu21755	NM_001143827.3 Latest version!	Homo sapiens microtubule associated protein RP/EB family member 2 (MAPRE2), transcript variant 3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$139.30 $199.00
View Old Accession Versions >>
OHu21755	NM_001143827.2	Homo sapiens microtubule associated protein RP/EB family member 2 (MAPRE2), transcript variant 3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$139.30 $199.00
OHu21207	NM_001256420.1	Homo sapiens microtubule associated protein RP/EB family member 2 (MAPRE2), transcript variant 4, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$139.30 $199.00
OHu21066	NM_014268.3	Homo sapiens microtubule associated protein RP/EB family member 2 (MAPRE2), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$69.30 $99.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

MAPRE2 ( NM_014268.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_055083.1 Homo sapiens microtubule associated protein RP/EB family member 2 (MAPRE2), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu21066
Clone ID Related Accession (Same CDS sequence)	NM_014268.3 , NM_014268.4
Accession Version	NM_014268.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 984bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-10-10
Organism	Homo sapiens(human)
Product	microtubule-associated protein RP/EB family member 2 isoform 1
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DC354326.1, BC007318.2, AC015967.8 and BM673789.1. On May 17, 2019 this sequence version replaced NM_014268.3. Transcript Variant: This variant (1) encodes the longest isoform (1). Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1803617.123849.1, SRR1803611.245781.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000300249.10/ ENSP00000300249.4 RefSeq Select criteria :: based on conservation, expression, longest protein ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGCCTGGGC CGACCCAAAC CCTGTCCCCA AATGGCGAGA ACAACAACGA CATCATCCAG 
GATAATAACG GGACCATCAT TCCTTTCCGG AAGCACACAG TGCGCGGGGA GCGTTCCTAC 
AGTTGGGGAA TGGCGGTCAA TGTGTATTCT ACCTCGATAA CCCAAGAGAC TATGAGCAGA 
CATGACATCA TTGCATGGGT TAATGACATA GTATCTTTAA ACTACACAAA AGTGGAACAG 
CTTTGTTCAG GAGCGGCCTA TTGCCAATTC ATGGACATGC TCTTCCCTGG CTGCATTAGT 
TTGAAGAAAG TAAAATTTCA AGCAAAGCTG GAACATGAAT ATATTCACAA TTTTAAACTT 
CTGCAAGCAT CATTTAAGCG AATGAACGTT GATAAGGTAA TTCCAGTGGA GAAGCTAGTG 
AAAGGACGTT TCCAGGACAA CCTGGATTTT ATTCAATGGT TTAAGAAATT CTATGATGCT 
AACTACGATG GGAAGGAGTA TGATCCTGTA GAGGCACGAC AAGGGCAAGA TGCAATTCCT 
CCTCCTGACC CTGGTGAACA GATCTTCAAC CTGCCAAAAA AGTCTCACCA TGCAAACTCC 
CCCACAGCAG GTGCAGCTAA ATCAAGTCCA GCAGCTAAAC CAGGATCCAC ACCTTCTCGA 
CCCTCATCAG CCAAAAGGGC TTCTTCCAGT GGCTCAGCAT CCAAATCCGA TAAAGATTTA 
GAAACGCAGG TCATACAGCT TAATGAACAG GTACATTCAT TAAAACTTGC CCTTGAAGGC 
GTGGAAAAGG AAAGGGATTT CTACTTTGGG AAGTTGAGAG AGATCGAGCT ACTCTGCCAA 
GAACACGGGC AGGAAAATGA TGACCTCGTG CAGAGACTAA TGGACATCCT GTATGCTTCA 
GAAGAACACG AGGGCCACAC AGAAGAGCCG GAAGCAGAGG AGCAAGCCCA CGAACAGCAG 
CCCCCGCAGC AGGAAGAGTA CTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_055083.1
CDS	128..1111
Translation	MPGPTQTLSPNGENNNDIIQDNNGTIIPFRKHTVRGERSYSWGMAVNVYSTSITQETMSRHDIIAWVNDIVSLNYTKVEQLCSGAAYCQFMDMLFPGCISLKKVKFQAKLEHEYIHNFKLLQASFKRMNVDKVIPVEKLVKGRFQDNLDFIQWFKKFYDANYDGKEYDPVEARQGQDAIPPPDPGEQIFNLPKKSHHANSPTAGAAKSSPAAKPGSTPSRPSSAKRASSSGSASKSDKDLETQVIQLNEQVHSLKLALEGVEKERDFYFGKLREIELLCQEHGQENDDLVQRLMDILYASEEHEGHTEEPEAEEQAHEQQPPQQEEY

Target ORF information:

RefSeq Version	NM_014268.4
Organism	Homo sapiens(human)
Definition	Homo sapiens microtubule associated protein RP/EB family member 2 (MAPRE2), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_014268.4

ORF Insert Sequence:

ATGCCTGGGC CGACCCAAAC CCTGTCCCCA AATGGCGAGA ACAACAACGA CATCATCCAG 
GATAATAACG GGACCATCAT TCCTTTCCGG AAGCACACAG TGCGCGGGGA GCGTTCCTAC 
AGTTGGGGAA TGGCGGTCAA TGTGTATTCT ACCTCGATAA CCCAAGAGAC TATGAGCAGA 
CATGACATCA TTGCATGGGT TAATGACATA GTATCTTTAA ACTACACAAA AGTGGAACAG 
CTTTGTTCAG GAGCGGCCTA TTGCCAATTC ATGGACATGC TCTTCCCTGG CTGCATTAGT 
TTGAAGAAAG TAAAATTTCA AGCAAAGCTG GAACATGAAT ATATTCACAA TTTTAAACTT 
CTGCAAGCAT CATTTAAGCG AATGAACGTT GATAAGGTAA TTCCAGTGGA GAAGCTAGTG 
AAAGGACGTT TCCAGGACAA CCTGGATTTT ATTCAATGGT TTAAGAAATT CTATGATGCT 
AACTACGATG GGAAGGAGTA TGATCCTGTA GAGGCACGAC AAGGGCAAGA TGCAATTCCT 
CCTCCTGACC CTGGTGAACA GATCTTCAAC CTGCCAAAAA AGTCTCACCA TGCAAACTCC 
CCCACAGCAG GTGCAGCTAA ATCAAGTCCA GCAGCTAAAC CAGGATCCAC ACCTTCTCGA 
CCCTCATCAG CCAAAAGGGC TTCTTCCAGT GGCTCAGCAT CCAAATCCGA TAAAGATTTA 
GAAACGCAGG TCATACAGCT TAATGAACAG GTACATTCAT TAAAACTTGC CCTTGAAGGC 
GTGGAAAAGG AAAGGGATTT CTACTTTGGG AAGTTGAGAG AGATCGAGCT ACTCTGCCAA 
GAACACGGGC AGGAAAATGA TGACCTCGTG CAGAGACTAA TGGACATCCT GTATGCTTCA 
GAAGAACACG AGGGCCACAC AGAAGAGCCG GAAGCAGAGG AGCAAGCCCA CGAACAGCAG 
CCCCCGCAGC AGGAAGAGTA CTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

MAPRE2 ( NM_001143826.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_001137298.1 Homo sapiens microtubule associated protein RP/EB family member 2 (MAPRE2), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu20780
Clone ID Related Accession (Same CDS sequence)	NM_001143826.2
Accession Version	NM_001143826.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 855bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-10-10
Organism	Homo sapiens(human)
Product	microtubule-associated protein RP/EB family member 2 isoform 2
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DC341673.1, AC009277.4, BC007318.2, AC015967.8 and BM673789.1. This sequence is a reference standard in the RefSeqGene project. On Jan 25, 2012 this sequence version replaced NM_001143826.1. Transcript Variant: This variant (2) differs in the 5' UTR, lacks a portion of the 5' coding region, and uses a downstream in-frame start codon, compared to variant 1. The encoded isoform (2) is shorter at the N-terminus, compared to isoform 1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1660805.124079.1, SRR1660803.24670.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1968540 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGCGGTCA ATGTGTATTC TACCTCGATA ACCCAAGAGA CTATGAGCAG ACATGACATC 
ATTGCATGGG TTAATGACAT AGTATCTTTA AACTACACAA AAGTGGAACA GCTTTGTTCA 
GGAGCGGCCT ATTGCCAATT CATGGACATG CTCTTCCCTG GCTGCATTAG TTTGAAGAAA 
GTAAAATTTC AAGCAAAGCT GGAACATGAA TATATTCACA ATTTTAAACT TCTGCAAGCA 
TCATTTAAGC GAATGAACGT TGATAAGGTA ATTCCAGTGG AGAAGCTAGT GAAAGGACGT 
TTCCAGGACA ACCTGGATTT TATTCAATGG TTTAAGAAAT TCTATGATGC TAACTACGAT 
GGGAAGGAGT ATGATCCTGT AGAGGCACGA CAAGGGCAAG ATGCAATTCC TCCTCCTGAC 
CCTGGTGAAC AGATCTTCAA CCTGCCAAAA AAGTCTCACC ATGCAAACTC CCCCACAGCA 
GGTGCAGCTA AATCAAGTCC AGCAGCTAAA CCAGGATCCA CACCTTCTCG ACCCTCATCA 
GCCAAAAGGG CTTCTTCCAG TGGCTCAGCA TCCAAATCCG ATAAAGATTT AGAAACGCAG 
GTCATACAGC TTAATGAACA GGTACATTCA TTAAAACTTG CCCTTGAAGG CGTGGAAAAG 
GAAAGGGATT TCTACTTTGG GAAGTTGAGA GAGATCGAGC TACTCTGCCA AGAACACGGG 
CAGGAAAATG ATGACCTCGT GCAGAGACTA ATGGACATCC TGTATGCTTC AGAAGAACAC 
GAGGGCCACA CAGAAGAGCC GGAAGCAGAG GAGCAAGCCC ACGAACAGCA GCCCCCGCAG 
CAGGAAGAGT ACTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001137298.1
CDS	222..1076
Translation	MAVNVYSTSITQETMSRHDIIAWVNDIVSLNYTKVEQLCSGAAYCQFMDMLFPGCISLKKVKFQAKLEHEYIHNFKLLQASFKRMNVDKVIPVEKLVKGRFQDNLDFIQWFKKFYDANYDGKEYDPVEARQGQDAIPPPDPGEQIFNLPKKSHHANSPTAGAAKSSPAAKPGSTPSRPSSAKRASSSGSASKSDKDLETQVIQLNEQVHSLKLALEGVEKERDFYFGKLREIELLCQEHGQENDDLVQRLMDILYASEEHEGHTEEPEAEEQAHEQQPPQQEEY

Target ORF information:

RefSeq Version	NM_001143826.2
Organism	Homo sapiens(human)
Definition	Homo sapiens microtubule associated protein RP/EB family member 2 (MAPRE2), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001143826.2

ORF Insert Sequence:

ATGGCGGTCA ATGTGTATTC TACCTCGATA ACCCAAGAGA CTATGAGCAG ACATGACATC 
ATTGCATGGG TTAATGACAT AGTATCTTTA AACTACACAA AAGTGGAACA GCTTTGTTCA 
GGAGCGGCCT ATTGCCAATT CATGGACATG CTCTTCCCTG GCTGCATTAG TTTGAAGAAA 
GTAAAATTTC AAGCAAAGCT GGAACATGAA TATATTCACA ATTTTAAACT TCTGCAAGCA 
TCATTTAAGC GAATGAACGT TGATAAGGTA ATTCCAGTGG AGAAGCTAGT GAAAGGACGT 
TTCCAGGACA ACCTGGATTT TATTCAATGG TTTAAGAAAT TCTATGATGC TAACTACGAT 
GGGAAGGAGT ATGATCCTGT AGAGGCACGA CAAGGGCAAG ATGCAATTCC TCCTCCTGAC 
CCTGGTGAAC AGATCTTCAA CCTGCCAAAA AAGTCTCACC ATGCAAACTC CCCCACAGCA 
GGTGCAGCTA AATCAAGTCC AGCAGCTAAA CCAGGATCCA CACCTTCTCG ACCCTCATCA 
GCCAAAAGGG CTTCTTCCAG TGGCTCAGCA TCCAAATCCG ATAAAGATTT AGAAACGCAG 
GTCATACAGC TTAATGAACA GGTACATTCA TTAAAACTTG CCCTTGAAGG CGTGGAAAAG 
GAAAGGGATT TCTACTTTGG GAAGTTGAGA GAGATCGAGC TACTCTGCCA AGAACACGGG 
CAGGAAAATG ATGACCTCGT GCAGAGACTA ATGGACATCC TGTATGCTTC AGAAGAACAC 
GAGGGCCACA CAGAAGAGCC GGAAGCAGAG GAGCAAGCCC ACGAACAGCA GCCCCCGCAG 
CAGGAAGAGT ACTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

MAPRE2 ( NM_014268.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_055083.1 Homo sapiens microtubule associated protein RP/EB family member 2 (MAPRE2), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu21066
Clone ID Related Accession (Same CDS sequence)	NM_014268.3 , NM_014268.4
Accession Version	NM_014268.3	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 984bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-02-22
Organism	Homo sapiens(human)
Product	microtubule-associated protein RP/EB family member 2 isoform 1
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DC354326.1, BC007318.2, AC015967.8 and BM673789.1. On Jan 25, 2012 this sequence version replaced NM_014268.2. Transcript Variant: This variant (1) encodes the longest isoform (1). Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1803612.19326.1, SRR1803615.79712.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGCCTGGGC CGACCCAAAC CCTGTCCCCA AATGGCGAGA ACAACAACGA CATCATCCAG 
GATAATAACG GGACCATCAT TCCTTTCCGG AAGCACACAG TGCGCGGGGA GCGTTCCTAC 
AGTTGGGGAA TGGCGGTCAA TGTGTATTCT ACCTCGATAA CCCAAGAGAC TATGAGCAGA 
CATGACATCA TTGCATGGGT TAATGACATA GTATCTTTAA ACTACACAAA AGTGGAACAG 
CTTTGTTCAG GAGCGGCCTA TTGCCAATTC ATGGACATGC TCTTCCCTGG CTGCATTAGT 
TTGAAGAAAG TAAAATTTCA AGCAAAGCTG GAACATGAAT ATATTCACAA TTTTAAACTT 
CTGCAAGCAT CATTTAAGCG AATGAACGTT GATAAGGTAA TTCCAGTGGA GAAGCTAGTG 
AAAGGACGTT TCCAGGACAA CCTGGATTTT ATTCAATGGT TTAAGAAATT CTATGATGCT 
AACTACGATG GGAAGGAGTA TGATCCTGTA GAGGCACGAC AAGGGCAAGA TGCAATTCCT 
CCTCCTGACC CTGGTGAACA GATCTTCAAC CTGCCAAAAA AGTCTCACCA TGCAAACTCC 
CCCACAGCAG GTGCAGCTAA ATCAAGTCCA GCAGCTAAAC CAGGATCCAC ACCTTCTCGA 
CCCTCATCAG CCAAAAGGGC TTCTTCCAGT GGCTCAGCAT CCAAATCCGA TAAAGATTTA 
GAAACGCAGG TCATACAGCT TAATGAACAG GTACATTCAT TAAAACTTGC CCTTGAAGGC 
GTGGAAAAGG AAAGGGATTT CTACTTTGGG AAGTTGAGAG AGATCGAGCT ACTCTGCCAA 
GAACACGGGC AGGAAAATGA TGACCTCGTG CAGAGACTAA TGGACATCCT GTATGCTTCA 
GAAGAACACG AGGGCCACAC AGAAGAGCCG GAAGCAGAGG AGCAAGCCCA CGAACAGCAG 
CCCCCGCAGC AGGAAGAGTA CTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_055083.1
CDS	181..1164
Translation	MPGPTQTLSPNGENNNDIIQDNNGTIIPFRKHTVRGERSYSWGMAVNVYSTSITQETMSRHDIIAWVNDIVSLNYTKVEQLCSGAAYCQFMDMLFPGCISLKKVKFQAKLEHEYIHNFKLLQASFKRMNVDKVIPVEKLVKGRFQDNLDFIQWFKKFYDANYDGKEYDPVEARQGQDAIPPPDPGEQIFNLPKKSHHANSPTAGAAKSSPAAKPGSTPSRPSSAKRASSSGSASKSDKDLETQVIQLNEQVHSLKLALEGVEKERDFYFGKLREIELLCQEHGQENDDLVQRLMDILYASEEHEGHTEEPEAEEQAHEQQPPQQEEY

Target ORF information:

RefSeq Version	NM_014268.3
Organism	Homo sapiens(human)
Definition	Homo sapiens microtubule associated protein RP/EB family member 2 (MAPRE2), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_014268.3

ORF Insert Sequence:

ATGCCTGGGC CGACCCAAAC CCTGTCCCCA AATGGCGAGA ACAACAACGA CATCATCCAG 
GATAATAACG GGACCATCAT TCCTTTCCGG AAGCACACAG TGCGCGGGGA GCGTTCCTAC 
AGTTGGGGAA TGGCGGTCAA TGTGTATTCT ACCTCGATAA CCCAAGAGAC TATGAGCAGA 
CATGACATCA TTGCATGGGT TAATGACATA GTATCTTTAA ACTACACAAA AGTGGAACAG 
CTTTGTTCAG GAGCGGCCTA TTGCCAATTC ATGGACATGC TCTTCCCTGG CTGCATTAGT 
TTGAAGAAAG TAAAATTTCA AGCAAAGCTG GAACATGAAT ATATTCACAA TTTTAAACTT 
CTGCAAGCAT CATTTAAGCG AATGAACGTT GATAAGGTAA TTCCAGTGGA GAAGCTAGTG 
AAAGGACGTT TCCAGGACAA CCTGGATTTT ATTCAATGGT TTAAGAAATT CTATGATGCT 
AACTACGATG GGAAGGAGTA TGATCCTGTA GAGGCACGAC AAGGGCAAGA TGCAATTCCT 
CCTCCTGACC CTGGTGAACA GATCTTCAAC CTGCCAAAAA AGTCTCACCA TGCAAACTCC 
CCCACAGCAG GTGCAGCTAA ATCAAGTCCA GCAGCTAAAC CAGGATCCAC ACCTTCTCGA 
CCCTCATCAG CCAAAAGGGC TTCTTCCAGT GGCTCAGCAT CCAAATCCGA TAAAGATTTA 
GAAACGCAGG TCATACAGCT TAATGAACAG GTACATTCAT TAAAACTTGC CCTTGAAGGC 
GTGGAAAAGG AAAGGGATTT CTACTTTGGG AAGTTGAGAG AGATCGAGCT ACTCTGCCAA 
GAACACGGGC AGGAAAATGA TGACCTCGTG CAGAGACTAA TGGACATCCT GTATGCTTCA 
GAAGAACACG AGGGCCACAC AGAAGAGCCG GAAGCAGAGG AGCAAGCCCA CGAACAGCAG 
CCCCCGCAGC AGGAAGAGTA CTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

MAPRE2 ( NM_001256420.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_001243349.1 Homo sapiens microtubule associated protein RP/EB family member 2 (MAPRE2), transcript variant 4, mRNA.

Price & Availability↑

CloneID	OHu21207
Clone ID Related Accession (Same CDS sequence)	NM_001256420.2 , NM_001256420.1
Accession Version	NM_001256420.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 825bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-10-10
Organism	Homo sapiens(human)
Product	microtubule-associated protein RP/EB family member 2 isoform 4
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AK090945.1, AC015967.8 and BM673789.1. On Jun 1, 2019 this sequence version replaced NM_001256420.1. Transcript Variant: This variant (4) lacks an alternate exon in the 5' coding region and uses an alternate start codon, compared to variant 1. The encoded isoform (4) has a distinct N-terminus and is shorter than isoform 1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1803612.34496.1, SRR1660803.90288.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968540, SAMEA2145743 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGCGAGAA CAACAACGAC ATCATCCAGG ATAATAACGG GACCATCATT CCTTTCCGGA 
AGCACACAGT GCGCGGGGAG CGTTCCTACA GGAGCGGCCT ATTGCCAATT CATGGACATG 
CTCTTCCCTG GCTGCATTAG TTTGAAGAAA GTAAAATTTC AAGCAAAGCT GGAACATGAA 
TATATTCACA ATTTTAAACT TCTGCAAGCA TCATTTAAGC GAATGAACGT TGATAAGGTA 
ATTCCAGTGG AGAAGCTAGT GAAAGGACGT TTCCAGGACA ACCTGGATTT TATTCAATGG 
TTTAAGAAAT TCTATGATGC TAACTACGAT GGGAAGGAGT ATGATCCTGT AGAGGCACGA 
CAAGGGCAAG ATGCAATTCC TCCTCCTGAC CCTGGTGAAC AGATCTTCAA CCTGCCAAAA 
AAGTCTCACC ATGCAAACTC CCCCACAGCA GGTGCAGCTA AATCAAGTCC AGCAGCTAAA 
CCAGGATCCA CACCTTCTCG ACCCTCATCA GCCAAAAGGG CTTCTTCCAG TGGCTCAGCA 
TCCAAATCCG ATAAAGATTT AGAAACGCAG GTCATACAGC TTAATGAACA GGTACATTCA 
TTAAAACTTG CCCTTGAAGG CGTGGAAAAG GAAAGGGATT TCTACTTTGG GAAGTTGAGA 
GAGATCGAGC TACTCTGCCA AGAACACGGG CAGGAAAATG ATGACCTCGT GCAGAGACTA 
ATGGACATCC TGTATGCTTC AGAAGAACAC GAGGGCCACA CAGAAGAGCC GGAAGCAGAG 
GAGCAAGCCC ACGAACAGCA GCCCCCGCAG CAGGAAGAGT ACTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001243349.1
CDS	159..983
Translation	MARTTTTSSRIITGPSFLSGSTQCAGSVPTGAAYCQFMDMLFPGCISLKKVKFQAKLEHEYIHNFKLLQASFKRMNVDKVIPVEKLVKGRFQDNLDFIQWFKKFYDANYDGKEYDPVEARQGQDAIPPPDPGEQIFNLPKKSHHANSPTAGAAKSSPAAKPGSTPSRPSSAKRASSSGSASKSDKDLETQVIQLNEQVHSLKLALEGVEKERDFYFGKLREIELLCQEHGQENDDLVQRLMDILYASEEHEGHTEEPEAEEQAHEQQPPQQEEY

Target ORF information:

RefSeq Version	NM_001256420.2
Organism	Homo sapiens(human)
Definition	Homo sapiens microtubule associated protein RP/EB family member 2 (MAPRE2), transcript variant 4, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001256420.2

ORF Insert Sequence:

ATGGCGAGAA CAACAACGAC ATCATCCAGG ATAATAACGG GACCATCATT CCTTTCCGGA 
AGCACACAGT GCGCGGGGAG CGTTCCTACA GGAGCGGCCT ATTGCCAATT CATGGACATG 
CTCTTCCCTG GCTGCATTAG TTTGAAGAAA GTAAAATTTC AAGCAAAGCT GGAACATGAA 
TATATTCACA ATTTTAAACT TCTGCAAGCA TCATTTAAGC GAATGAACGT TGATAAGGTA 
ATTCCAGTGG AGAAGCTAGT GAAAGGACGT TTCCAGGACA ACCTGGATTT TATTCAATGG 
TTTAAGAAAT TCTATGATGC TAACTACGAT GGGAAGGAGT ATGATCCTGT AGAGGCACGA 
CAAGGGCAAG ATGCAATTCC TCCTCCTGAC CCTGGTGAAC AGATCTTCAA CCTGCCAAAA 
AAGTCTCACC ATGCAAACTC CCCCACAGCA GGTGCAGCTA AATCAAGTCC AGCAGCTAAA 
CCAGGATCCA CACCTTCTCG ACCCTCATCA GCCAAAAGGG CTTCTTCCAG TGGCTCAGCA 
TCCAAATCCG ATAAAGATTT AGAAACGCAG GTCATACAGC TTAATGAACA GGTACATTCA 
TTAAAACTTG CCCTTGAAGG CGTGGAAAAG GAAAGGGATT TCTACTTTGG GAAGTTGAGA 
GAGATCGAGC TACTCTGCCA AGAACACGGG CAGGAAAATG ATGACCTCGT GCAGAGACTA 
ATGGACATCC TGTATGCTTC AGAAGAACAC GAGGGCCACA CAGAAGAGCC GGAAGCAGAG 
GAGCAAGCCC ACGAACAGCA GCCCCCGCAG CAGGAAGAGT ACTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

MAPRE2 ( NM_001256420.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001243349.1 Homo sapiens microtubule associated protein RP/EB family member 2 (MAPRE2), transcript variant 4, mRNA.

Price & Availability↑

CloneID	OHu21207
Clone ID Related Accession (Same CDS sequence)	NM_001256420.2 , NM_001256420.1
Accession Version	NM_001256420.1	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 825bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2018-12-14
Organism	Homo sapiens(human)
Product	microtubule-associated protein RP/EB family member 2 isoform 4
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DC354326.1, AK090945.1, AC015967.8 and BM673789.1. On Jan 26, 2012 this sequence version replaced NR_026570.1. Transcript Variant: This variant (4) lacks an alternate exon in the 5' coding region and uses an alternate start codon, compared to variant 1. The encoded isoform (4) has a distinct N-terminus and is shorter than isoform 1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1803612.34496.1, SRR1803611.84452.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968540, SAMEA2145743 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGCGAGAA CAACAACGAC ATCATCCAGG ATAATAACGG GACCATCATT CCTTTCCGGA 
AGCACACAGT GCGCGGGGAG CGTTCCTACA GGAGCGGCCT ATTGCCAATT CATGGACATG 
CTCTTCCCTG GCTGCATTAG TTTGAAGAAA GTAAAATTTC AAGCAAAGCT GGAACATGAA 
TATATTCACA ATTTTAAACT TCTGCAAGCA TCATTTAAGC GAATGAACGT TGATAAGGTA 
ATTCCAGTGG AGAAGCTAGT GAAAGGACGT TTCCAGGACA ACCTGGATTT TATTCAATGG 
TTTAAGAAAT TCTATGATGC TAACTACGAT GGGAAGGAGT ATGATCCTGT AGAGGCACGA 
CAAGGGCAAG ATGCAATTCC TCCTCCTGAC CCTGGTGAAC AGATCTTCAA CCTGCCAAAA 
AAGTCTCACC ATGCAAACTC CCCCACAGCA GGTGCAGCTA AATCAAGTCC AGCAGCTAAA 
CCAGGATCCA CACCTTCTCG ACCCTCATCA GCCAAAAGGG CTTCTTCCAG TGGCTCAGCA 
TCCAAATCCG ATAAAGATTT AGAAACGCAG GTCATACAGC TTAATGAACA GGTACATTCA 
TTAAAACTTG CCCTTGAAGG CGTGGAAAAG GAAAGGGATT TCTACTTTGG GAAGTTGAGA 
GAGATCGAGC TACTCTGCCA AGAACACGGG CAGGAAAATG ATGACCTCGT GCAGAGACTA 
ATGGACATCC TGTATGCTTC AGAAGAACAC GAGGGCCACA CAGAAGAGCC GGAAGCAGAG 
GAGCAAGCCC ACGAACAGCA GCCCCCGCAG CAGGAAGAGT ACTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001243349.1
CDS	212..1036
Translation	MARTTTTSSRIITGPSFLSGSTQCAGSVPTGAAYCQFMDMLFPGCISLKKVKFQAKLEHEYIHNFKLLQASFKRMNVDKVIPVEKLVKGRFQDNLDFIQWFKKFYDANYDGKEYDPVEARQGQDAIPPPDPGEQIFNLPKKSHHANSPTAGAAKSSPAAKPGSTPSRPSSAKRASSSGSASKSDKDLETQVIQLNEQVHSLKLALEGVEKERDFYFGKLREIELLCQEHGQENDDLVQRLMDILYASEEHEGHTEEPEAEEQAHEQQPPQQEEY

Target ORF information:

RefSeq Version	NM_001256420.1
Organism	Homo sapiens(human)
Definition	Homo sapiens microtubule associated protein RP/EB family member 2 (MAPRE2), transcript variant 4, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001256420.1

ORF Insert Sequence:

ATGGCGAGAA CAACAACGAC ATCATCCAGG ATAATAACGG GACCATCATT CCTTTCCGGA 
AGCACACAGT GCGCGGGGAG CGTTCCTACA GGAGCGGCCT ATTGCCAATT CATGGACATG 
CTCTTCCCTG GCTGCATTAG TTTGAAGAAA GTAAAATTTC AAGCAAAGCT GGAACATGAA 
TATATTCACA ATTTTAAACT TCTGCAAGCA TCATTTAAGC GAATGAACGT TGATAAGGTA 
ATTCCAGTGG AGAAGCTAGT GAAAGGACGT TTCCAGGACA ACCTGGATTT TATTCAATGG 
TTTAAGAAAT TCTATGATGC TAACTACGAT GGGAAGGAGT ATGATCCTGT AGAGGCACGA 
CAAGGGCAAG ATGCAATTCC TCCTCCTGAC CCTGGTGAAC AGATCTTCAA CCTGCCAAAA 
AAGTCTCACC ATGCAAACTC CCCCACAGCA GGTGCAGCTA AATCAAGTCC AGCAGCTAAA 
CCAGGATCCA CACCTTCTCG ACCCTCATCA GCCAAAAGGG CTTCTTCCAG TGGCTCAGCA 
TCCAAATCCG ATAAAGATTT AGAAACGCAG GTCATACAGC TTAATGAACA GGTACATTCA 
TTAAAACTTG CCCTTGAAGG CGTGGAAAAG GAAAGGGATT TCTACTTTGG GAAGTTGAGA 
GAGATCGAGC TACTCTGCCA AGAACACGGG CAGGAAAATG ATGACCTCGT GCAGAGACTA 
ATGGACATCC TGTATGCTTC AGAAGAACAC GAGGGCCACA CAGAAGAGCC GGAAGCAGAG 
GAGCAAGCCC ACGAACAGCA GCCCCCGCAG CAGGAAGAGT ACTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

MAPRE2 ( NM_001143827.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_001137299.1 Homo sapiens microtubule associated protein RP/EB family member 2 (MAPRE2), transcript variant 3, mRNA.

Price & Availability↑

CloneID	OHu21755
Clone ID Related Accession (Same CDS sequence)	NM_001143827.3 , NM_001143827.2
Accession Version	NM_001143827.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 948bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-10-10
Organism	Homo sapiens(human)
Product	microtubule-associated protein RP/EB family member 2 isoform 3
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AK294833.1, AC015967.8 and BM673789.1. On May 31, 2019 this sequence version replaced NM_001143827.2. Transcript Variant: This variant (3) has alternate 5' exon structure and it thus differs in the 5' UTR and 5' coding region, compared to variant 1. The encoded isoform (3) has a distinct N-terminus and is shorter than isoform 1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1803617.21045.1, SRR1803612.142565.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968540, SAMEA2142586 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGAAACAGA ACAGAGATCA AAAGTGTCCT GTTTCCCAGA GGAACAGTTC ATTTCAACAG 
CCAGGGAGAA AGCCTGGATG CTCAAGTTGG GGAATGGCGG TCAATGTGTA TTCTACCTCG 
ATAACCCAAG AGACTATGAG CAGACATGAC ATCATTGCAT GGGTTAATGA CATAGTATCT 
TTAAACTACA CAAAAGTGGA ACAGCTTTGT TCAGGAGCGG CCTATTGCCA ATTCATGGAC 
ATGCTCTTCC CTGGCTGCAT TAGTTTGAAG AAAGTAAAAT TTCAAGCAAA GCTGGAACAT 
GAATATATTC ACAATTTTAA ACTTCTGCAA GCATCATTTA AGCGAATGAA CGTTGATAAG 
GTAATTCCAG TGGAGAAGCT AGTGAAAGGA CGTTTCCAGG ACAACCTGGA TTTTATTCAA 
TGGTTTAAGA AATTCTATGA TGCTAACTAC GATGGGAAGG AGTATGATCC TGTAGAGGCA 
CGACAAGGGC AAGATGCAAT TCCTCCTCCT GACCCTGGTG AACAGATCTT CAACCTGCCA 
AAAAAGTCTC ACCATGCAAA CTCCCCCACA GCAGGTGCAG CTAAATCAAG TCCAGCAGCT 
AAACCAGGAT CCACACCTTC TCGACCCTCA TCAGCCAAAA GGGCTTCTTC CAGTGGCTCA 
GCATCCAAAT CCGATAAAGA TTTAGAAACG CAGGTCATAC AGCTTAATGA ACAGGTACAT 
TCATTAAAAC TTGCCCTTGA AGGCGTGGAA AAGGAAAGGG ATTTCTACTT TGGGAAGTTG 
AGAGAGATCG AGCTACTCTG CCAAGAACAC GGGCAGGAAA ATGATGACCT CGTGCAGAGA 
CTAATGGACA TCCTGTATGC TTCAGAAGAA CACGAGGGCC ACACAGAAGA GCCGGAAGCA 
GAGGAGCAAG CCCACGAACA GCAGCCCCCG CAGCAGGAAG AGTACTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001137299.1
CDS	151..1098
Translation	MKQNRDQKCPVSQRNSSFQQPGRKPGCSSWGMAVNVYSTSITQETMSRHDIIAWVNDIVSLNYTKVEQLCSGAAYCQFMDMLFPGCISLKKVKFQAKLEHEYIHNFKLLQASFKRMNVDKVIPVEKLVKGRFQDNLDFIQWFKKFYDANYDGKEYDPVEARQGQDAIPPPDPGEQIFNLPKKSHHANSPTAGAAKSSPAAKPGSTPSRPSSAKRASSSGSASKSDKDLETQVIQLNEQVHSLKLALEGVEKERDFYFGKLREIELLCQEHGQENDDLVQRLMDILYASEEHEGHTEEPEAEEQAHEQQPPQQEEY

Target ORF information:

RefSeq Version	NM_001143827.3
Organism	Homo sapiens(human)
Definition	Homo sapiens microtubule associated protein RP/EB family member 2 (MAPRE2), transcript variant 3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001143827.3

ORF Insert Sequence:

ATGAAACAGA ACAGAGATCA AAAGTGTCCT GTTTCCCAGA GGAACAGTTC ATTTCAACAG 
CCAGGGAGAA AGCCTGGATG CTCAAGTTGG GGAATGGCGG TCAATGTGTA TTCTACCTCG 
ATAACCCAAG AGACTATGAG CAGACATGAC ATCATTGCAT GGGTTAATGA CATAGTATCT 
TTAAACTACA CAAAAGTGGA ACAGCTTTGT TCAGGAGCGG CCTATTGCCA ATTCATGGAC 
ATGCTCTTCC CTGGCTGCAT TAGTTTGAAG AAAGTAAAAT TTCAAGCAAA GCTGGAACAT 
GAATATATTC ACAATTTTAA ACTTCTGCAA GCATCATTTA AGCGAATGAA CGTTGATAAG 
GTAATTCCAG TGGAGAAGCT AGTGAAAGGA CGTTTCCAGG ACAACCTGGA TTTTATTCAA 
TGGTTTAAGA AATTCTATGA TGCTAACTAC GATGGGAAGG AGTATGATCC TGTAGAGGCA 
CGACAAGGGC AAGATGCAAT TCCTCCTCCT GACCCTGGTG AACAGATCTT CAACCTGCCA 
AAAAAGTCTC ACCATGCAAA CTCCCCCACA GCAGGTGCAG CTAAATCAAG TCCAGCAGCT 
AAACCAGGAT CCACACCTTC TCGACCCTCA TCAGCCAAAA GGGCTTCTTC CAGTGGCTCA 
GCATCCAAAT CCGATAAAGA TTTAGAAACG CAGGTCATAC AGCTTAATGA ACAGGTACAT 
TCATTAAAAC TTGCCCTTGA AGGCGTGGAA AAGGAAAGGG ATTTCTACTT TGGGAAGTTG 
AGAGAGATCG AGCTACTCTG CCAAGAACAC GGGCAGGAAA ATGATGACCT CGTGCAGAGA 
CTAATGGACA TCCTGTATGC TTCAGAAGAA CACGAGGGCC ACACAGAAGA GCCGGAAGCA 
GAGGAGCAAG CCCACGAACA GCAGCCCCCG CAGCAGGAAG AGTACTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

MAPRE2 ( NM_001143827.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_001137299.1 Homo sapiens microtubule associated protein RP/EB family member 2 (MAPRE2), transcript variant 3, mRNA.

Price & Availability↑

CloneID	OHu21755
Clone ID Related Accession (Same CDS sequence)	NM_001143827.3 , NM_001143827.2
Accession Version	NM_001143827.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 948bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2018-12-14
Organism	Homo sapiens(human)
Product	microtubule-associated protein RP/EB family member 2 isoform 3
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DC335558.1, AK294833.1, AC015967.8 and BM673789.1. On Jan 26, 2012 this sequence version replaced NM_001143827.1. Transcript Variant: This variant (3) has alternate 5' exon structure and it thus differs in the 5' UTR and 5' coding region, compared to variant 1. The encoded isoform (3) has a distinct N-terminus and is shorter than isoform 1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1803617.21045.1, SRR1803612.142565.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968540, SAMEA2142586 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGAAACAGA ACAGAGATCA AAAGTGTCCT GTTTCCCAGA GGAACAGTTC ATTTCAACAG 
CCAGGGAGAA AGCCTGGATG CTCAAGTTGG GGAATGGCGG TCAATGTGTA TTCTACCTCG 
ATAACCCAAG AGACTATGAG CAGACATGAC ATCATTGCAT GGGTTAATGA CATAGTATCT 
TTAAACTACA CAAAAGTGGA ACAGCTTTGT TCAGGAGCGG CCTATTGCCA ATTCATGGAC 
ATGCTCTTCC CTGGCTGCAT TAGTTTGAAG AAAGTAAAAT TTCAAGCAAA GCTGGAACAT 
GAATATATTC ACAATTTTAA ACTTCTGCAA GCATCATTTA AGCGAATGAA CGTTGATAAG 
GTAATTCCAG TGGAGAAGCT AGTGAAAGGA CGTTTCCAGG ACAACCTGGA TTTTATTCAA 
TGGTTTAAGA AATTCTATGA TGCTAACTAC GATGGGAAGG AGTATGATCC TGTAGAGGCA 
CGACAAGGGC AAGATGCAAT TCCTCCTCCT GACCCTGGTG AACAGATCTT CAACCTGCCA 
AAAAAGTCTC ACCATGCAAA CTCCCCCACA GCAGGTGCAG CTAAATCAAG TCCAGCAGCT 
AAACCAGGAT CCACACCTTC TCGACCCTCA TCAGCCAAAA GGGCTTCTTC CAGTGGCTCA 
GCATCCAAAT CCGATAAAGA TTTAGAAACG CAGGTCATAC AGCTTAATGA ACAGGTACAT 
TCATTAAAAC TTGCCCTTGA AGGCGTGGAA AAGGAAAGGG ATTTCTACTT TGGGAAGTTG 
AGAGAGATCG AGCTACTCTG CCAAGAACAC GGGCAGGAAA ATGATGACCT CGTGCAGAGA 
CTAATGGACA TCCTGTATGC TTCAGAAGAA CACGAGGGCC ACACAGAAGA GCCGGAAGCA 
GAGGAGCAAG CCCACGAACA GCAGCCCCCG CAGCAGGAAG AGTACTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001137299.1
CDS	275..1222
Translation	MKQNRDQKCPVSQRNSSFQQPGRKPGCSSWGMAVNVYSTSITQETMSRHDIIAWVNDIVSLNYTKVEQLCSGAAYCQFMDMLFPGCISLKKVKFQAKLEHEYIHNFKLLQASFKRMNVDKVIPVEKLVKGRFQDNLDFIQWFKKFYDANYDGKEYDPVEARQGQDAIPPPDPGEQIFNLPKKSHHANSPTAGAAKSSPAAKPGSTPSRPSSAKRASSSGSASKSDKDLETQVIQLNEQVHSLKLALEGVEKERDFYFGKLREIELLCQEHGQENDDLVQRLMDILYASEEHEGHTEEPEAEEQAHEQQPPQQEEY

Target ORF information:

RefSeq Version	NM_001143827.2
Organism	Homo sapiens(human)
Definition	Homo sapiens microtubule associated protein RP/EB family member 2 (MAPRE2), transcript variant 3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001143827.2

ORF Insert Sequence:

ATGAAACAGA ACAGAGATCA AAAGTGTCCT GTTTCCCAGA GGAACAGTTC ATTTCAACAG 
CCAGGGAGAA AGCCTGGATG CTCAAGTTGG GGAATGGCGG TCAATGTGTA TTCTACCTCG 
ATAACCCAAG AGACTATGAG CAGACATGAC ATCATTGCAT GGGTTAATGA CATAGTATCT 
TTAAACTACA CAAAAGTGGA ACAGCTTTGT TCAGGAGCGG CCTATTGCCA ATTCATGGAC 
ATGCTCTTCC CTGGCTGCAT TAGTTTGAAG AAAGTAAAAT TTCAAGCAAA GCTGGAACAT 
GAATATATTC ACAATTTTAA ACTTCTGCAA GCATCATTTA AGCGAATGAA CGTTGATAAG 
GTAATTCCAG TGGAGAAGCT AGTGAAAGGA CGTTTCCAGG ACAACCTGGA TTTTATTCAA 
TGGTTTAAGA AATTCTATGA TGCTAACTAC GATGGGAAGG AGTATGATCC TGTAGAGGCA 
CGACAAGGGC AAGATGCAAT TCCTCCTCCT GACCCTGGTG AACAGATCTT CAACCTGCCA 
AAAAAGTCTC ACCATGCAAA CTCCCCCACA GCAGGTGCAG CTAAATCAAG TCCAGCAGCT 
AAACCAGGAT CCACACCTTC TCGACCCTCA TCAGCCAAAA GGGCTTCTTC CAGTGGCTCA 
GCATCCAAAT CCGATAAAGA TTTAGAAACG CAGGTCATAC AGCTTAATGA ACAGGTACAT 
TCATTAAAAC TTGCCCTTGA AGGCGTGGAA AAGGAAAGGG ATTTCTACTT TGGGAAGTTG 
AGAGAGATCG AGCTACTCTG CCAAGAACAC GGGCAGGAAA ATGATGACCT CGTGCAGAGA 
CTAATGGACA TCCTGTATGC TTCAGAAGAA CACGAGGGCC ACACAGAAGA GCCGGAAGCA 
GAGGAGCAAG CCCACGAACA GCAGCCCCCG CAGCAGGAAG AGTACTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Architecture of the human interactome defines protein communities and disease networks.
Nature545(7655)505-509(2017 05)
Huttlin EL,Bruckner RJ,Paulo JA,Cannon JR,Ting L,Baltier K,Colby G,Gebreab F,Gygi MP,Parzen H,Szpyt J,Tam S,Zarraga G,Pontano-Vaites L,Swarup S,White AE,Schweppe DK,Rad R,Erickson BK,Obar RA,Guruharsha KG,Li K,Artavanis-Tsakonas S,Gygi SP,Harper JW

An organelle-specific protein landscape identifies novel diseases and molecular mechanisms.
Nature communications711491(2016 May)
Boldt K,van Reeuwijk J,Lu Q,Koutroumpas K,Nguyen TM,Texier Y,van Beersum SE,Horn N,Willer JR,Mans DA,Dougherty G,Lamers IJ,Coene KL,Arts HH,Betts MJ,Beyer T,Bolat E,Gloeckner CJ,Haidari K,Hetterschijt L,Iaconis D,Jenkins D,Klose F,Knapp B,Latour B,Letteboer SJ,Marcelis CL,Mitic D,Morleo M,Oud MM,Riemersma M,Rix S,Terhal PA,Toedt G,van Dam TJ,de Vrieze E,Wissinger Y,Wu KM,Apic G,Beales PL,Blacque OE,Gibson TJ,Huynen MA,Katsanis N,Kremer H,Omran H,van Wijk E,Wolfrum U,Kepes F,Davis EE,Franco B,Giles RH,Ueffing M,Russell RB,Roepman R,

Pooled-matrix protein interaction screens using Barcode Fusion Genetics.
Molecular systems biology12(4)863(2016 Apr)
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Phosphorylation of EB2 by Aurora B and CDK1 ensures mitotic progression and genome stability.
Nature communications711117(2016 Mar)
Iimori M,Watanabe S,Kiyonari S,Matsuoka K,Sakasai R,Saeki H,Oki E,Kitao H,Maehara Y

Mutations in Either TUBB or MAPRE2 Cause Circumferential Skin Creases Kunze Type.
American journal of human genetics97(6)790-800(2015 Dec)
Isrie M,Breuss M,Tian G,Hansen AH,Cristofoli F,Morandell J,Kupchinsky ZA,Sifrim A,Rodriguez-Rodriguez CM,Dapena EP,Doonanco K,Leonard N,Tinsa F,Moortgat S,Ulucan H,Koparir E,Karaca E,Katsanis N,Marton V,Vermeesch JR,Davis EE,Cowan NJ,Keays DA,Van Esch H

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MAPRE2 cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

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Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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