SUB1 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	SUB1
Entrez Gene ID	10923
Full Name	SUB1 homolog, transcriptional regulator
Synonyms	P15,PC4,p14
General protein information	Preferred Names SUB1 homolog, transcriptional regulator Names activated RNA polymerase II transcriptional coactivator p15 activated RNA polymerase II transcription cofactor 4 positive cofactor 4
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 5 Map Location: 5p13.3
Disorder MIM:	600503

mRNA and Protein(s)

mRNA	Protein	Name
NM_006713.3	NP_006704.3	activated RNA polymerase II transcriptional coactivator p15
XM_011513944.2	XP_011512246.1	activated RNA polymerase II transcriptional coactivator p15 isoform X1
XM_017008987.1	XP_016864476.1	activated RNA polymerase II transcriptional coactivator p15 isoform X1
XM_011513944.1	XP_011512246.1	activated RNA polymerase II transcriptional coactivator p15 isoform X1
XM_011513943.1	XP_011512245.1	activated RNA polymerase II transcriptional coactivator p15 isoform X1
XM_017008986.1	XP_016864475.1	activated RNA polymerase II transcriptional coactivator p15 isoform X1
XM_011513944.3	XP_011512246.1	activated RNA polymerase II transcriptional coactivator p15 isoform X1
NM_006713.4	NP_006704.3	activated RNA polymerase II transcriptional coactivator p15

Pathways from BioSystems

Homologies

Pan troglodytes (chimpanzee)	SUB1	XP_001154622.1
	SUB1	XP_002804378.1
Danio rerio (zebrafish)	sub1b	NP_001002505.1
Gallus gallus (chicken)	LOC777191	XP_001236661.2
Xenopus tropicalis (tropical clawed frog)	sub1	NP_001004871.1
Homo sapiens (human)	SUB1	NP_006704.3
Canis lupus familiaris (dog)	SUB1	XP_536425.3
Gallus gallus (chicken)	SUB1	NP_001008479.1
Danio rerio (zebrafish)	sub1a	NP_001018376.1
Mus musculus (house mouse)	Sub1	NP_035424.1
Bos taurus (cattle)	SUB1	NP_001098877.1
Rattus norvegicus (Norway rat)	Sub1	NP_001009618.1

Gene Ontology
Bibliography

Related articles in PubMed

Sub1 and RNAPII, until termination does them part.
Calvo O
Transcription9(1)52-60(2018)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Yeast Sub1 and human PC4 are G-quadruplex binding proteins that suppress genome instability at co-transcriptionally formed G4 DNA.
Title: Yeast Sub1 and human PC4 are G-quadruplex binding proteins that suppress genome instability at co-transcriptionally formed G4 DNA.

these data provide a novel mode of PC4 binding to a DNA secondary structure that remains within the framework of the model for binding to ssDNA. Additionally, consideration of the PC4-G4DNA interaction could provide insight into the biological functions of PC4, which remain incompletely understood.
Title: A biochemical and biophysical model of G-quadruplex DNA recognition by positive coactivator of transcription 4.

Results show elevated expression of SUB1 in aggressive prostate cancer. Knockdown of SUB1 in prostate cancer cells resulted in reduced cell proliferation, invasion and migration.
Title: MicroRNA-101 regulated transcriptional modulator SUB1 plays a role in prostate cancer.

PC4 associates with Aurora A and Aurora B and undergoes phosphorylation, following which PC4 activates both Aurora A and B to sustain optimal kinase activity to maintain the phosphorylation gradient for the proper functioning of the mitotic machinery.
Title: Multifunctional human transcriptional coactivator protein PC4 is a substrate of Aurora kinases and activates the Aurora enzymes.

SMYD3 interacts with the human positive coactivator 4 (PC4) and that such interaction potentiates a group of genes whose expression is linked to cell proliferation and invasion.
Title: Cooperation between SMYD3 and PC4 drives a distinct transcriptional program in cancer cells.

The following SUB1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the SUB1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu11241	NM_006713.4 Latest version!	Homo sapiens SUB1 regulator of transcription (SUB1), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
OHu11241	XM_017008987.1 Latest version!	Homo sapiens SUB1 regulator of transcription (SUB1), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
OHu11241	XM_017008986.1 Latest version!	Homo sapiens SUB1 regulator of transcription (SUB1), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
OHu11241	XM_011513943.1 Latest version!	Homo sapiens SUB1 homolog (S. cerevisiae) (SUB1), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
OHu11241	XM_011513944.3 Latest version!	Homo sapiens SUB1 regulator of transcription (SUB1), transcript variant X3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
View Old Accession Versions >>
OHu11241	XM_011513944.1	Homo sapiens SUB1 homolog (S. cerevisiae) (SUB1), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
OHu11241	XM_011513944.2	Homo sapiens SUB1 homolog, transcriptional regulator (SUB1), transcript variant X3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
OHu11241	NM_006713.3	Homo sapiens SUB1 homolog, transcriptional regulator (SUB1), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
Hide Old Accession Versions >>

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

SUB1 ( NM_006713.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_006704.3 Homo sapiens SUB1 homolog, transcriptional regulator (SUB1), mRNA.

Price & Availability↑

CloneID	OHu11241
Clone ID Related Accession (Same CDS sequence)	NM_006713.3 , XM_011513944.2 , XM_017008987.1 , XM_011513944.1 , XM_011513943.1 , XM_017008986.1 , XM_011513944.3 , NM_006713.4
Accession Version	NM_006713.3	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 384bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-09-24
Organism	Homo sapiens(human)
Product	activated RNA polymerase II transcriptional coactivator p15
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BX472106.1, BC010537.1, BC071655.1 and AC074134.3. On Dec 12, 2008 this sequence version replaced NM_006713.2. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC071655.1, SRR1660809.35730.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGCCTAAAT CAAAGGAACT TGTTTCTTCA AGCTCTTCTG GCAGTGATTC TGACAGTGAG 
GTTGACAAAA AGTTAAAGAG GAAAAAGCAA GTTGCTCCAG AAAAACCTGT AAAGAAACAA 
AAGACAGGTG AGACTTCGAG AGCCCTGTCA TCTTCTAAAC AGAGCAGCAG CAGCAGAGAT 
GATAACATGT TTCAGATTGG GAAAATGAGG TACGTTAGTG TTCGCGATTT TAAAGGCAAA 
GTGCTAATTG ATATTAGAGA ATATTGGATG GATCCTGAAG GTGAAATGAA ACCAGGAAGA 
AAAGGTATTT CTTTAAATCC AGAACAATGG AGCCAGCTGA AGGAACAGAT TTCTGACATT 
GATGATGCAG TAAGAAAACT GTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_006704.3
CDS	129..512
Translation	MPKSKELVSSSSSGSDSDSEVDKKLKRKKQVAPEKPVKKQKTGETSRALSSSKQSSSSRDDNMFQIGKMRYVSVRDFKGKVLIDIREYWMDPEGEMKPGRKGISLNPEQWSQLKEQISDIDDAVRKL

Target ORF information:

RefSeq Version	NM_006713.3
Organism	Homo sapiens(human)
Definition	Homo sapiens SUB1 homolog, transcriptional regulator (SUB1), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_006713.3

ORF Insert Sequence:

ATGCCTAAAT CAAAGGAACT TGTTTCTTCA AGCTCTTCTG GCAGTGATTC TGACAGTGAG 
GTTGACAAAA AGTTAAAGAG GAAAAAGCAA GTTGCTCCAG AAAAACCTGT AAAGAAACAA 
AAGACAGGTG AGACTTCGAG AGCCCTGTCA TCTTCTAAAC AGAGCAGCAG CAGCAGAGAT 
GATAACATGT TTCAGATTGG GAAAATGAGG TACGTTAGTG TTCGCGATTT TAAAGGCAAA 
GTGCTAATTG ATATTAGAGA ATATTGGATG GATCCTGAAG GTGAAATGAA ACCAGGAAGA 
AAAGGTATTT CTTTAAATCC AGAACAATGG AGCCAGCTGA AGGAACAGAT TTCTGACATT 
GATGATGCAG TAAGAAAACT GTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

SUB1 ( NM_006713.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_006704.3 Homo sapiens SUB1 regulator of transcription (SUB1), mRNA.

Price & Availability↑

CloneID	OHu11241
Clone ID Related Accession (Same CDS sequence)	NM_006713.3 , XM_011513944.2 , XM_017008987.1 , XM_011513944.1 , XM_011513943.1 , XM_017008986.1 , XM_011513944.3 , NM_006713.4
Accession Version	NM_006713.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 384bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-03
Organism	Homo sapiens(human)
Product	activated RNA polymerase II transcriptional coactivator p15
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BX472106.1, BC010537.1, BC071655.1 and AC074134.3. On Nov 22, 2018 this sequence version replaced NM_006713.3. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC071655.1, SRR1660807.205718.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000265073.9/ ENSP00000265073.4 RefSeq Select criteria :: based on conservation, expression, longest protein ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGCCTAAAT CAAAGGAACT TGTTTCTTCA AGCTCTTCTG GCAGTGATTC TGACAGTGAG 
GTTGACAAAA AGTTAAAGAG GAAAAAGCAA GTTGCTCCAG AAAAACCTGT AAAGAAACAA 
AAGACAGGTG AGACTTCGAG AGCCCTGTCA TCTTCTAAAC AGAGCAGCAG CAGCAGAGAT 
GATAACATGT TTCAGATTGG GAAAATGAGG TACGTTAGTG TTCGCGATTT TAAAGGCAAA 
GTGCTAATTG ATATTAGAGA ATATTGGATG GATCCTGAAG GTGAAATGAA ACCAGGAAGA 
AAAGGTATTT CTTTAAATCC AGAACAATGG AGCCAGCTGA AGGAACAGAT TTCTGACATT 
GATGATGCAG TAAGAAAACT GTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_006704.3
CDS	71..454
Translation	MPKSKELVSSSSSGSDSDSEVDKKLKRKKQVAPEKPVKKQKTGETSRALSSSKQSSSSRDDNMFQIGKMRYVSVRDFKGKVLIDIREYWMDPEGEMKPGRKGISLNPEQWSQLKEQISDIDDAVRKL

Target ORF information:

RefSeq Version	NM_006713.4
Organism	Homo sapiens(human)
Definition	Homo sapiens SUB1 regulator of transcription (SUB1), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_006713.4

ORF Insert Sequence:

ATGCCTAAAT CAAAGGAACT TGTTTCTTCA AGCTCTTCTG GCAGTGATTC TGACAGTGAG 
GTTGACAAAA AGTTAAAGAG GAAAAAGCAA GTTGCTCCAG AAAAACCTGT AAAGAAACAA 
AAGACAGGTG AGACTTCGAG AGCCCTGTCA TCTTCTAAAC AGAGCAGCAG CAGCAGAGAT 
GATAACATGT TTCAGATTGG GAAAATGAGG TACGTTAGTG TTCGCGATTT TAAAGGCAAA 
GTGCTAATTG ATATTAGAGA ATATTGGATG GATCCTGAAG GTGAAATGAA ACCAGGAAGA 
AAAGGTATTT CTTTAAATCC AGAACAATGG AGCCAGCTGA AGGAACAGAT TTCTGACATT 
GATGATGCAG TAAGAAAACT GTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

SUB1 ( XM_011513944.2 ) cDNA ORF clone, Homo sapiens(human) -> XP_011512246.1 Homo sapiens SUB1 homolog, transcriptional regulator (SUB1), transcript variant X3, mRNA.

Price & Availability↑

CloneID	OHu11241
Clone ID Related Accession (Same CDS sequence)	NM_006713.3 , XM_011513944.2 , XM_017008987.1 , XM_011513944.1 , XM_011513943.1 , XM_017008986.1 , XM_011513944.3 , NM_006713.4
Accession Version	XM_011513944.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 384bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-06-05
Organism	Homo sapiens(human)
Product	activated RNA polymerase II transcriptional coactivator p15 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000005.10) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 6, 2016 this sequence version replaced XM_011513944.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGCCTAAAT CAAAGGAACT TGTTTCTTCA AGCTCTTCTG GCAGTGATTC TGACAGTGAG 
GTTGACAAAA AGTTAAAGAG GAAAAAGCAA GTTGCTCCAG AAAAACCTGT AAAGAAACAA 
AAGACAGGTG AGACTTCGAG AGCCCTGTCA TCTTCTAAAC AGAGCAGCAG CAGCAGAGAT 
GATAACATGT TTCAGATTGG GAAAATGAGG TACGTTAGTG TTCGCGATTT TAAAGGCAAA 
GTGCTAATTG ATATTAGAGA ATATTGGATG GATCCTGAAG GTGAAATGAA ACCAGGAAGA 
AAAGGTATTT CTTTAAATCC AGAACAATGG AGCCAGCTGA AGGAACAGAT TTCTGACATT 
GATGATGCAG TAAGAAAACT GTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_011512246.1
CDS	382..765
Translation	MPKSKELVSSSSSGSDSDSEVDKKLKRKKQVAPEKPVKKQKTGETSRALSSSKQSSSSRDDNMFQIGKMRYVSVRDFKGKVLIDIREYWMDPEGEMKPGRKGISLNPEQWSQLKEQISDIDDAVRKL

Target ORF information:

RefSeq Version	XM_011513944.2
Organism	Homo sapiens(human)
Definition	Homo sapiens SUB1 homolog, transcriptional regulator (SUB1), transcript variant X3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011513944.2

ORF Insert Sequence:

ATGCCTAAAT CAAAGGAACT TGTTTCTTCA AGCTCTTCTG GCAGTGATTC TGACAGTGAG 
GTTGACAAAA AGTTAAAGAG GAAAAAGCAA GTTGCTCCAG AAAAACCTGT AAAGAAACAA 
AAGACAGGTG AGACTTCGAG AGCCCTGTCA TCTTCTAAAC AGAGCAGCAG CAGCAGAGAT 
GATAACATGT TTCAGATTGG GAAAATGAGG TACGTTAGTG TTCGCGATTT TAAAGGCAAA 
GTGCTAATTG ATATTAGAGA ATATTGGATG GATCCTGAAG GTGAAATGAA ACCAGGAAGA 
AAAGGTATTT CTTTAAATCC AGAACAATGG AGCCAGCTGA AGGAACAGAT TTCTGACATT 
GATGATGCAG TAAGAAAACT GTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

SUB1 ( XM_017008987.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_016864476.1 Homo sapiens SUB1 regulator of transcription (SUB1), transcript variant X2, mRNA.

Price & Availability↑

CloneID	OHu11241
Clone ID Related Accession (Same CDS sequence)	NM_006713.3 , XM_011513944.2 , XM_017008987.1 , XM_011513944.1 , XM_011513943.1 , XM_017008986.1 , XM_011513944.3 , NM_006713.4
Accession Version	XM_017008987.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 384bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	activated RNA polymerase II transcriptional coactivator p15 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000005.10) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGCCTAAAT CAAAGGAACT TGTTTCTTCA AGCTCTTCTG GCAGTGATTC TGACAGTGAG 
GTTGACAAAA AGTTAAAGAG GAAAAAGCAA GTTGCTCCAG AAAAACCTGT AAAGAAACAA 
AAGACAGGTG AGACTTCGAG AGCCCTGTCA TCTTCTAAAC AGAGCAGCAG CAGCAGAGAT 
GATAACATGT TTCAGATTGG GAAAATGAGG TACGTTAGTG TTCGCGATTT TAAAGGCAAA 
GTGCTAATTG ATATTAGAGA ATATTGGATG GATCCTGAAG GTGAAATGAA ACCAGGAAGA 
AAAGGTATTT CTTTAAATCC AGAACAATGG AGCCAGCTGA AGGAACAGAT TTCTGACATT 
GATGATGCAG TAAGAAAACT GTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_016864476.1
CDS	102..485
Translation	MPKSKELVSSSSSGSDSDSEVDKKLKRKKQVAPEKPVKKQKTGETSRALSSSKQSSSSRDDNMFQIGKMRYVSVRDFKGKVLIDIREYWMDPEGEMKPGRKGISLNPEQWSQLKEQISDIDDAVRKL

Target ORF information:

RefSeq Version	XM_017008987.1
Organism	Homo sapiens(human)
Definition	Homo sapiens SUB1 regulator of transcription (SUB1), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017008987.1

ORF Insert Sequence:

ATGCCTAAAT CAAAGGAACT TGTTTCTTCA AGCTCTTCTG GCAGTGATTC TGACAGTGAG 
GTTGACAAAA AGTTAAAGAG GAAAAAGCAA GTTGCTCCAG AAAAACCTGT AAAGAAACAA 
AAGACAGGTG AGACTTCGAG AGCCCTGTCA TCTTCTAAAC AGAGCAGCAG CAGCAGAGAT 
GATAACATGT TTCAGATTGG GAAAATGAGG TACGTTAGTG TTCGCGATTT TAAAGGCAAA 
GTGCTAATTG ATATTAGAGA ATATTGGATG GATCCTGAAG GTGAAATGAA ACCAGGAAGA 
AAAGGTATTT CTTTAAATCC AGAACAATGG AGCCAGCTGA AGGAACAGAT TTCTGACATT 
GATGATGCAG TAAGAAAACT GTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

SUB1 ( XM_011513944.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_011512246.1 Homo sapiens SUB1 homolog (S. cerevisiae) (SUB1), transcript variant X2, mRNA.

Price & Availability↑

CloneID	OHu11241
Clone ID Related Accession (Same CDS sequence)	NM_006713.3 , XM_011513944.2 , XM_017008987.1 , XM_011513944.1 , XM_011513943.1 , XM_017008986.1 , XM_011513944.3 , NM_006713.4
Accession Version	XM_011513944.1	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 384bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2015-03-11
Organism	Homo sapiens(Human)
Product	activated RNA polymerase II transcriptional coactivator p15 isoform X1
Comment

ATGCCTAAAT CAAAGGAACT TGTTTCTTCA AGCTCTTCTG GCAGTGATTC TGACAGTGAG 
GTTGACAAAA AGTTAAAGAG GAAAAAGCAA GTTGCTCCAG AAAAACCTGT AAAGAAACAA 
AAGACAGGTG AGACTTCGAG AGCCCTGTCA TCTTCTAAAC AGAGCAGCAG CAGCAGAGAT 
GATAACATGT TTCAGATTGG GAAAATGAGG TACGTTAGTG TTCGCGATTT TAAAGGCAAA 
GTGCTAATTG ATATTAGAGA ATATTGGATG GATCCTGAAG GTGAAATGAA ACCAGGAAGA 
AAAGGTATTT CTTTAAATCC AGAACAATGG AGCCAGCTGA AGGAACAGAT TTCTGACATT 
GATGATGCAG TAAGAAAACT GTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_011512246.1
Translation	MPKSKELVSSSSSGSDSDSEVDKKLKRKKQVAPEKPVKKQKTGETSRALSSSKQSSSSRDDNMFQIGKMRYVSVRDFKGKVLIDIREYWMDPEGEMKPGRKGISLNPEQWSQLKEQISDIDDAVRKL

Target ORF information:

RefSeq Version	XM_011513944.1
Organism	Homo sapiens(Human)
Definition	Homo sapiens SUB1 homolog (S. cerevisiae) (SUB1), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011513944.1

ORF Insert Sequence:

ATGCCTAAAT CAAAGGAACT TGTTTCTTCA AGCTCTTCTG GCAGTGATTC TGACAGTGAG 
GTTGACAAAA AGTTAAAGAG GAAAAAGCAA GTTGCTCCAG AAAAACCTGT AAAGAAACAA 
AAGACAGGTG AGACTTCGAG AGCCCTGTCA TCTTCTAAAC AGAGCAGCAG CAGCAGAGAT 
GATAACATGT TTCAGATTGG GAAAATGAGG TACGTTAGTG TTCGCGATTT TAAAGGCAAA 
GTGCTAATTG ATATTAGAGA ATATTGGATG GATCCTGAAG GTGAAATGAA ACCAGGAAGA 
AAAGGTATTT CTTTAAATCC AGAACAATGG AGCCAGCTGA AGGAACAGAT TTCTGACATT 
GATGATGCAG TAAGAAAACT GTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

SUB1 ( XM_011513943.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_011512245.1 Homo sapiens SUB1 homolog (S. cerevisiae) (SUB1), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OHu11241
Clone ID Related Accession (Same CDS sequence)	NM_006713.3 , XM_011513944.2 , XM_017008987.1 , XM_011513944.1 , XM_011513943.1 , XM_017008986.1 , XM_011513944.3 , NM_006713.4
Accession Version	XM_011513943.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 384bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2015-03-11
Organism	Homo sapiens(Human)
Product	activated RNA polymerase II transcriptional coactivator p15 isoform X1
Comment

ATGCCTAAAT CAAAGGAACT TGTTTCTTCA AGCTCTTCTG GCAGTGATTC TGACAGTGAG 
GTTGACAAAA AGTTAAAGAG GAAAAAGCAA GTTGCTCCAG AAAAACCTGT AAAGAAACAA 
AAGACAGGTG AGACTTCGAG AGCCCTGTCA TCTTCTAAAC AGAGCAGCAG CAGCAGAGAT 
GATAACATGT TTCAGATTGG GAAAATGAGG TACGTTAGTG TTCGCGATTT TAAAGGCAAA 
GTGCTAATTG ATATTAGAGA ATATTGGATG GATCCTGAAG GTGAAATGAA ACCAGGAAGA 
AAAGGTATTT CTTTAAATCC AGAACAATGG AGCCAGCTGA AGGAACAGAT TTCTGACATT 
GATGATGCAG TAAGAAAACT GTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_011512245.1
Translation	MPKSKELVSSSSSGSDSDSEVDKKLKRKKQVAPEKPVKKQKTGETSRALSSSKQSSSSRDDNMFQIGKMRYVSVRDFKGKVLIDIREYWMDPEGEMKPGRKGISLNPEQWSQLKEQISDIDDAVRKL

Target ORF information:

RefSeq Version	XM_011513943.1
Organism	Homo sapiens(Human)
Definition	Homo sapiens SUB1 homolog (S. cerevisiae) (SUB1), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011513943.1

ORF Insert Sequence:

ATGCCTAAAT CAAAGGAACT TGTTTCTTCA AGCTCTTCTG GCAGTGATTC TGACAGTGAG 
GTTGACAAAA AGTTAAAGAG GAAAAAGCAA GTTGCTCCAG AAAAACCTGT AAAGAAACAA 
AAGACAGGTG AGACTTCGAG AGCCCTGTCA TCTTCTAAAC AGAGCAGCAG CAGCAGAGAT 
GATAACATGT TTCAGATTGG GAAAATGAGG TACGTTAGTG TTCGCGATTT TAAAGGCAAA 
GTGCTAATTG ATATTAGAGA ATATTGGATG GATCCTGAAG GTGAAATGAA ACCAGGAAGA 
AAAGGTATTT CTTTAAATCC AGAACAATGG AGCCAGCTGA AGGAACAGAT TTCTGACATT 
GATGATGCAG TAAGAAAACT GTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

SUB1 ( XM_017008986.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_016864475.1 Homo sapiens SUB1 regulator of transcription (SUB1), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OHu11241
Clone ID Related Accession (Same CDS sequence)	NM_006713.3 , XM_011513944.2 , XM_017008987.1 , XM_011513944.1 , XM_011513943.1 , XM_017008986.1 , XM_011513944.3 , NM_006713.4
Accession Version	XM_017008986.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 384bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	activated RNA polymerase II transcriptional coactivator p15 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000005.10) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGCCTAAAT CAAAGGAACT TGTTTCTTCA AGCTCTTCTG GCAGTGATTC TGACAGTGAG 
GTTGACAAAA AGTTAAAGAG GAAAAAGCAA GTTGCTCCAG AAAAACCTGT AAAGAAACAA 
AAGACAGGTG AGACTTCGAG AGCCCTGTCA TCTTCTAAAC AGAGCAGCAG CAGCAGAGAT 
GATAACATGT TTCAGATTGG GAAAATGAGG TACGTTAGTG TTCGCGATTT TAAAGGCAAA 
GTGCTAATTG ATATTAGAGA ATATTGGATG GATCCTGAAG GTGAAATGAA ACCAGGAAGA 
AAAGGTATTT CTTTAAATCC AGAACAATGG AGCCAGCTGA AGGAACAGAT TTCTGACATT 
GATGATGCAG TAAGAAAACT GTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_016864475.1
CDS	225..608
Translation	MPKSKELVSSSSSGSDSDSEVDKKLKRKKQVAPEKPVKKQKTGETSRALSSSKQSSSSRDDNMFQIGKMRYVSVRDFKGKVLIDIREYWMDPEGEMKPGRKGISLNPEQWSQLKEQISDIDDAVRKL

Target ORF information:

RefSeq Version	XM_017008986.1
Organism	Homo sapiens(human)
Definition	Homo sapiens SUB1 regulator of transcription (SUB1), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017008986.1

ORF Insert Sequence:

ATGCCTAAAT CAAAGGAACT TGTTTCTTCA AGCTCTTCTG GCAGTGATTC TGACAGTGAG 
GTTGACAAAA AGTTAAAGAG GAAAAAGCAA GTTGCTCCAG AAAAACCTGT AAAGAAACAA 
AAGACAGGTG AGACTTCGAG AGCCCTGTCA TCTTCTAAAC AGAGCAGCAG CAGCAGAGAT 
GATAACATGT TTCAGATTGG GAAAATGAGG TACGTTAGTG TTCGCGATTT TAAAGGCAAA 
GTGCTAATTG ATATTAGAGA ATATTGGATG GATCCTGAAG GTGAAATGAA ACCAGGAAGA 
AAAGGTATTT CTTTAAATCC AGAACAATGG AGCCAGCTGA AGGAACAGAT TTCTGACATT 
GATGATGCAG TAAGAAAACT GTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

SUB1 ( XM_011513944.3 ) cDNA ORF clone, Homo sapiens(human) -> XP_011512246.1 Homo sapiens SUB1 regulator of transcription (SUB1), transcript variant X3, mRNA.

Price & Availability↑

CloneID	OHu11241
Clone ID Related Accession (Same CDS sequence)	NM_006713.3 , XM_011513944.2 , XM_017008987.1 , XM_011513944.1 , XM_011513943.1 , XM_017008986.1 , XM_011513944.3 , NM_006713.4
Accession Version	XM_011513944.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 384bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	activated RNA polymerase II transcriptional coactivator p15 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000005.10) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Mar 26, 2018 this sequence version replaced XM_011513944.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGCCTAAAT CAAAGGAACT TGTTTCTTCA AGCTCTTCTG GCAGTGATTC TGACAGTGAG 
GTTGACAAAA AGTTAAAGAG GAAAAAGCAA GTTGCTCCAG AAAAACCTGT AAAGAAACAA 
AAGACAGGTG AGACTTCGAG AGCCCTGTCA TCTTCTAAAC AGAGCAGCAG CAGCAGAGAT 
GATAACATGT TTCAGATTGG GAAAATGAGG TACGTTAGTG TTCGCGATTT TAAAGGCAAA 
GTGCTAATTG ATATTAGAGA ATATTGGATG GATCCTGAAG GTGAAATGAA ACCAGGAAGA 
AAAGGTATTT CTTTAAATCC AGAACAATGG AGCCAGCTGA AGGAACAGAT TTCTGACATT 
GATGATGCAG TAAGAAAACT GTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_011512246.1
CDS	379..762
Translation	MPKSKELVSSSSSGSDSDSEVDKKLKRKKQVAPEKPVKKQKTGETSRALSSSKQSSSSRDDNMFQIGKMRYVSVRDFKGKVLIDIREYWMDPEGEMKPGRKGISLNPEQWSQLKEQISDIDDAVRKL

Target ORF information:

RefSeq Version	XM_011513944.3
Organism	Homo sapiens(human)
Definition	Homo sapiens SUB1 regulator of transcription (SUB1), transcript variant X3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011513944.3

ORF Insert Sequence:

ATGCCTAAAT CAAAGGAACT TGTTTCTTCA AGCTCTTCTG GCAGTGATTC TGACAGTGAG 
GTTGACAAAA AGTTAAAGAG GAAAAAGCAA GTTGCTCCAG AAAAACCTGT AAAGAAACAA 
AAGACAGGTG AGACTTCGAG AGCCCTGTCA TCTTCTAAAC AGAGCAGCAG CAGCAGAGAT 
GATAACATGT TTCAGATTGG GAAAATGAGG TACGTTAGTG TTCGCGATTT TAAAGGCAAA 
GTGCTAATTG ATATTAGAGA ATATTGGATG GATCCTGAAG GTGAAATGAA ACCAGGAAGA 
AAAGGTATTT CTTTAAATCC AGAACAATGG AGCCAGCTGA AGGAACAGAT TTCTGACATT 
GATGATGCAG TAAGAAAACT GTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Sub1 and RNAPII, until termination does them part.
Transcription9(1)52-60(2018)
Calvo O

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SUB1 cDNA ORF clone, Homo sapiens(human)

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ORF Insert Sequence:

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Target ORF information:

ORF Insert Sequence:

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