EDAR cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	EDAR
Entrez Gene ID	10913
Full Name	ectodysplasin A receptor
Synonyms	DL,ECTD10A,ECTD10B,ED1R,ED3,ED5,EDA-A1R,EDA1R,EDA3,HRM1
General protein information	Preferred Names ectodysplasin A receptor Names tumor necrosis factor receptor superfamily member EDAR EDA-A1 receptor anhidrotic ectodysplasin receptor 1 downless homolog downless, mouse, homolog of ectodermal dysplasia receptor ectodysplasin 1, anhidrotic receptor
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 2 Map Location: 2q13
Summary	This gene encodes a member of the tumor necrosis factor receptor family. The encoded transmembrane protein is a receptor for the soluble ligand ectodysplasin A, and can activate the nuclear factor-kappaB, JNK, and caspase-independent cell death pathways. It is required for the development of hair, teeth, and other ectodermal derivatives. Mutations in this gene result in autosomal dominant and recessive forms of hypohidrotic ectodermal dysplasia. [provided by RefSeq, Jul 2008].
Disorder MIM:	604095
Disorder Html:	Ectodermal dysplasia 10A, hypohidrotic/hair/nail type, autosomal dominant, 129490 (3); Ectodermal dysplasia 10B, hypohidrotic/hair/tooth type, autosomal recessive, 224900 (3); [Hair morphology 1, hair thickness], 612630 (3)

mRNA and Protein(s)

mRNA	Protein	Name
XM_011510503.2	XP_011508805.2	tumor necrosis factor receptor superfamily member EDAR isoform X2
NM_022336.4	NP_071731.1	tumor necrosis factor receptor superfamily member EDAR precursor
XM_011510502.2	XP_011508804.2	tumor necrosis factor receptor superfamily member EDAR isoform X1
NM_022336.3	NP_071731.1	tumor necrosis factor receptor superfamily member EDAR precursor
XM_006712204.1	XP_006712267.1	tumor necrosis factor receptor superfamily member EDAR isoform X3

Pathways from BioSystems

Homologies

Bos taurus (cattle)	EDAR	XP_005212787.1
Pan troglodytes (chimpanzee)	EDAR	XP_001139583.1
Mus musculus (house mouse)	Edar	NP_034230.1
Gallus gallus (chicken)	EDAR	NP_001012629.1
Canis lupus familiaris (dog)	EDAR	XP_005626028.1
Danio rerio (zebrafish)	edar	NP_001108536.1
Xenopus tropicalis (tropical clawed frog)	edar	NP_001006820.1
Homo sapiens (human)	EDAR	NP_071731.1
Rattus norvegicus (Norway rat)	Edar	NP_001178828.1
	EDAR	XP_002799415.1

Gene Ontology
Bibliography

Related articles in PubMed

Evolutionary significance of selected EDAR variants in Tibetan high-altitude adaptations.
Shao J, Raza MS, Zhuoma B, Zeng C
Science China. Life sciences(2017 Aug)

Mutational spectrum of EDA and EDAR genes in a cohort of Mexican mestizo patients with hypohidrotic ectodermal dysplasia.
Monroy-Jaramillo N, Abad-Flores JD, Garc?a-Delgado C, Villase?or-Dom?nguez A, Mena-Cedillos C, Toledo-Bahena ME, Valencia-Herrera AM, S?nchez-Boiso A, Akaki-Carre?o YI, Del R?o Navarro B, Aguirre-Hern?ndez J, L?pez-L?pez M, Cervantes A, Cerb?n M, Mor?n-Barroso VF
Journal of the European Academy of Dermatology and Venereology : JEADV31(7)e321-e324(2017 Jul)

Association between EDAR Polymorphisms and Non-Syndromic Tooth Agenesis in the Chinese Han Population.
Chen YT, Liu HC, Han D, Liu Y, Feng HL
The Chinese journal of dental research : the official journal of the Scientific Section of the Chinese Stomatological Association (CSA)20(3)153-159(2017)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Results suggested that SNPs in EDAR could be a pathogenic factor for non-syndromic tooth agenesis. Furthermore, EDAR can be regarded as a marker gene for the risk of tooth agenesis.
Title: Association between EDAR Polymorphisms and Non-Syndromic Tooth Agenesis in the Chinese Han Population.

To evaluate the relative contribution of these variants, we performed a second genome-wide scan in 709 samples from the Uyghur, an admixed population with both eastern and western Eurasian ancestries. In Uyghurs, both EDAR (rs3827760: P = 1.92 x 10(-12)) and TCHH (rs11803731: P = 1.46 x 10(-3)) are associated with hair straightness, but EDAR (OR 0.415) has a greater effect than TCHH (OR 0.575).
Title: Genome-wide scans reveal variants at EDAR predominantly affecting hair straightness in Han Chinese and Uyghur populations.

Partial least square path model confirms EDARV370A systematically affect these weakly related ectodermal-derived characteristics, suggesting the pleiotropic effect of EDARV370A mainly plays roles in early embryo development
Title: EDARV370A associated facial characteristics in Uyghur population revealing further pleiotropic effects.

Individuals with a c.1072C > T mutation in the EDAR-gene displayed more hair shaft deformations confirming the role of EDAR for human hair follicle development and postnatal hair follicle cycling.
Title: Hair shaft structures in EDAR induced ectodermal dysplasia.

Four traits of ear pinna anatomic variation are associated with a functional variant in the EDAR gene, a key regulator of embryonic skin appendage development.
Title: A genome-wide association study identifies multiple loci for variation in human ear morphology.

The following EDAR gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the EDAR cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu18767	NM_022336.4 Latest version!	Homo sapiens ectodysplasin A receptor (EDAR), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$265.30 $379.00
OHu35774	XM_006712204.1 Latest version!	Homo sapiens ectodysplasin A receptor (EDAR), transcript variant X3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$223.30 $319.00
OHu88943	XM_011510503.2 Latest version!	Homo sapiens ectodysplasin A receptor (EDAR), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$223.30 $319.00
OHu88942	XM_011510502.2 Latest version!	Homo sapiens ectodysplasin A receptor (EDAR), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	14-16	$307.30 $439.00
View Old Accession Versions >>
OHu18767	NM_022336.3	Homo sapiens ectodysplasin A receptor (EDAR), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$265.30 $379.00
Hide Old Accession Versions >>

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***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

EDAR ( NM_022336.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_071731.1 Homo sapiens ectodysplasin A receptor (EDAR), mRNA.

Price & Availability↑

CloneID	OHu18767
Clone ID Related Accession (Same CDS sequence)	NM_022336.4 , NM_022336.3
Accession Version	NM_022336.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1347bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-11-04
Organism	Homo sapiens(human)
Product	tumor necrosis factor receptor superfamily member EDAR precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AC092160.5, AF130988.1, AC133784.2, AC073415.6 and AI017384.1. This sequence is a reference standard in the RefSeqGene project. On Nov 23, 2018 this sequence version replaced NM_022336.3. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AF130988.1, AK313781.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000258443.7/ ENSP00000258443.2 RefSeq Select criteria :: based on conservation, expression ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGGCCCATG TGGGGGACTG CACGCAGACG CCCTGGCTCC CCGTCCTGGT GGTGTCTCTG 
ATGTGCTCAG CCCGAGCGGA ATACTCAAAC TGCGGTGAGA ACGAGTACTA CAACCAGACT 
ACGGGGCTGT GCCAGGAGTG CCCCCCGTGT GGGCCGGGAG AGGAGCCCTA CCTGTCCTGT 
GGCTACGGCA CCAAAGACGA GGACTACGGC TGCGTCCCCT GCCCGGCGGA GAAGTTTTCC 
AAAGGAGGCT ACCAGATATG CAGGCGTCAC AAAGACTGTG AGGGCTTCTT CCGGGCCACC 
GTGCTGACAC CAGGGGACAT GGAGAATGAC GCTGAGTGTG GCCCTTGCCT CCCTGGCTAC 
TACATGCTGG AGAACAGACC GAGGAACATC TATGGCATGG TCTGCTACTC CTGCCTCCTG 
GCACCCCCCA ACACCAAGGA ATGTGTGGGA GCCACTTCAG GAGCTTCTGC CAACTTCCCT 
GGCACCTCGG GCAGCAGCAC CCTGTCTCCC TTCCAGCACG CCCACAAAGA ACTCTCAGGC 
CAAGGACACC TGGCCACTGC CCTGATCATT GCAATGTCCA CCATCTTCAT CATGGCCATC 
GCCATCGTCC TCATCATCAT GTTCTACATC CTGAAGACAA AGCCCTCTGC CCCAGCCTGT 
TGCACCAGCC ACCCGGGGAA GAGCGTGGAG GCCCAAGTGA GCAAGGACGA GGAGAAGAAA 
GAGGCCCCAG ACAACGTGGT GATGTTCTCC GAGAAGGATG AATTTGAGAA GCTGACAGCA 
ACTCCAGCAA AGCCCACCAA GAGCGAGAAC GATGCCTCAT CCGAGAATGA GCAGCTGCTG 
AGCCGGAGCG TCGACAGTGA TGAGGAGCCC GCCCCTGACA AGCAGGGCTC CCCGGAGCTG 
TGCCTGCTGT CGCTGGTTCA CCTGGCCAGG GAGAAGTCTG CCACCAGCAA CAAGTCAGCC 
GGGATTCAAA GCCGGAGGAA AAAGATCCTC GATGTGTATG CCAACGTGTG TGGAGTCGTG 
GAAGGTCTTA GCCCCACGGA GCTGCCATTT GATTGCCTCG AGAAGACTAG CCGAATGCTC 
AGCTCCACGT ACAACTCTGA GAAGGCTGTT GTGAAAACGT GGCGCCACCT CGCCGAGAGC 
TTCGGCCTGA AGAGGGATGA GATTGGGGGC ATGACAGACG GCATGCAACT CTTTGACCGC 
ATCAGCACGG CAGGCTACAG CATCCCTGAG CTACTCACAA AACTGGTGCA GATTGAGCGG 
CTGGATGCTG TGGAGTCCTT GTGTGCAGAC ATACTGGAGT GGGCGGGGGT TGTGCCACCT 
GCCTCCCAGC CACATGCTGC ATCCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_071731.1
CDS	280..1626
Translation	MAHVGDCTQTPWLPVLVVSLMCSARAEYSNCGENEYYNQTTGLCQECPPCGPGEEPYLSCGYGTKDEDYGCVPCPAEKFSKGGYQICRRHKDCEGFFRATVLTPGDMENDAECGPCLPGYYMLENRPRNIYGMVCYSCLLAPPNTKECVGATSGASANFPGTSGSSTLSPFQHAHKELSGQGHLATALIIAMSTIFIMAIAIVLIIMFYILKTKPSAPACCTSHPGKSVEAQVSKDEEKKEAPDNVVMFSEKDEFEKLTATPAKPTKSENDASSENEQLLSRSVDSDEEPAPDKQGSPELCLLSLVHLAREKSATSNKSAGIQSRRKKILDVYANVCGVVEGLSPTELPFDCLEKTSRMLSSTYNSEKAVVKTWRHLAESFGLKRDEIGGMTDGMQLFDRISTAGYSIPELLTKLVQIERLDAVESLCADILEWAGVVPPASQPHAAS

Target ORF information:

RefSeq Version	NM_022336.4
Organism	Homo sapiens(human)
Definition	Homo sapiens ectodysplasin A receptor (EDAR), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_022336.4

ORF Insert Sequence:

ATGGCCCATG TGGGGGACTG CACGCAGACG CCCTGGCTCC CCGTCCTGGT GGTGTCTCTG 
ATGTGCTCAG CCCGAGCGGA ATACTCAAAC TGCGGTGAGA ACGAGTACTA CAACCAGACT 
ACGGGGCTGT GCCAGGAGTG CCCCCCGTGT GGGCCGGGAG AGGAGCCCTA CCTGTCCTGT 
GGCTACGGCA CCAAAGACGA GGACTACGGC TGCGTCCCCT GCCCGGCGGA GAAGTTTTCC 
AAAGGAGGCT ACCAGATATG CAGGCGTCAC AAAGACTGTG AGGGCTTCTT CCGGGCCACC 
GTGCTGACAC CAGGGGACAT GGAGAATGAC GCTGAGTGTG GCCCTTGCCT CCCTGGCTAC 
TACATGCTGG AGAACAGACC GAGGAACATC TATGGCATGG TCTGCTACTC CTGCCTCCTG 
GCACCCCCCA ACACCAAGGA ATGTGTGGGA GCCACTTCAG GAGCTTCTGC CAACTTCCCT 
GGCACCTCGG GCAGCAGCAC CCTGTCTCCC TTCCAGCACG CCCACAAAGA ACTCTCAGGC 
CAAGGACACC TGGCCACTGC CCTGATCATT GCAATGTCCA CCATCTTCAT CATGGCCATC 
GCCATCGTCC TCATCATCAT GTTCTACATC CTGAAGACAA AGCCCTCTGC CCCAGCCTGT 
TGCACCAGCC ACCCGGGGAA GAGCGTGGAG GCCCAAGTGA GCAAGGACGA GGAGAAGAAA 
GAGGCCCCAG ACAACGTGGT GATGTTCTCC GAGAAGGATG AATTTGAGAA GCTGACAGCA 
ACTCCAGCAA AGCCCACCAA GAGCGAGAAC GATGCCTCAT CCGAGAATGA GCAGCTGCTG 
AGCCGGAGCG TCGACAGTGA TGAGGAGCCC GCCCCTGACA AGCAGGGCTC CCCGGAGCTG 
TGCCTGCTGT CGCTGGTTCA CCTGGCCAGG GAGAAGTCTG CCACCAGCAA CAAGTCAGCC 
GGGATTCAAA GCCGGAGGAA AAAGATCCTC GATGTGTATG CCAACGTGTG TGGAGTCGTG 
GAAGGTCTTA GCCCCACGGA GCTGCCATTT GATTGCCTCG AGAAGACTAG CCGAATGCTC 
AGCTCCACGT ACAACTCTGA GAAGGCTGTT GTGAAAACGT GGCGCCACCT CGCCGAGAGC 
TTCGGCCTGA AGAGGGATGA GATTGGGGGC ATGACAGACG GCATGCAACT CTTTGACCGC 
ATCAGCACGG CAGGCTACAG CATCCCTGAG CTACTCACAA AACTGGTGCA GATTGAGCGG 
CTGGATGCTG TGGAGTCCTT GTGTGCAGAC ATACTGGAGT GGGCGGGGGT TGTGCCACCT 
GCCTCCCAGC CACATGCTGC ATCCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

EDAR ( NM_022336.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_071731.1 Homo sapiens ectodysplasin A receptor (EDAR), mRNA.

Price & Availability↑

CloneID	OHu18767
Clone ID Related Accession (Same CDS sequence)	NM_022336.4 , NM_022336.3
Accession Version	NM_022336.3	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1347bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-12-17
Organism	Homo sapiens(human)
Product	tumor necrosis factor receptor superfamily member EDAR precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AF130988.1, AC092160.5, AC133784.2, AC073415.6 and AI017384.1. This sequence is a reference standard in the RefSeqGene project. On May 15, 2008 this sequence version replaced NM_022336.2. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AF130988.1, AK313781.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGCCCATG TGGGGGACTG CACGCAGACG CCCTGGCTCC CCGTCCTGGT GGTGTCTCTG 
ATGTGCTCAG CCCGAGCGGA ATACTCAAAC TGCGGTGAGA ACGAGTACTA CAACCAGACT 
ACGGGGCTGT GCCAGGAGTG CCCCCCGTGT GGGCCGGGAG AGGAGCCCTA CCTGTCCTGT 
GGCTACGGCA CCAAAGACGA GGACTACGGC TGCGTCCCCT GCCCGGCGGA GAAGTTTTCC 
AAAGGAGGCT ACCAGATATG CAGGCGTCAC AAAGACTGTG AGGGCTTCTT CCGGGCCACC 
GTGCTGACAC CAGGGGACAT GGAGAATGAC GCTGAGTGTG GCCCTTGCCT CCCTGGCTAC 
TACATGCTGG AGAACAGACC GAGGAACATC TATGGCATGG TCTGCTACTC CTGCCTCCTG 
GCACCCCCCA ACACCAAGGA ATGTGTGGGA GCCACTTCAG GAGCTTCTGC CAACTTCCCT 
GGCACCTCGG GCAGCAGCAC CCTGTCTCCC TTCCAGCACG CCCACAAAGA ACTCTCAGGC 
CAAGGACACC TGGCCACTGC CCTGATCATT GCAATGTCCA CCATCTTCAT CATGGCCATC 
GCCATCGTCC TCATCATCAT GTTCTACATC CTGAAGACAA AGCCCTCTGC CCCAGCCTGT 
TGCACCAGCC ACCCGGGGAA GAGCGTGGAG GCCCAAGTGA GCAAGGACGA GGAGAAGAAA 
GAGGCCCCAG ACAACGTGGT GATGTTCTCC GAGAAGGATG AATTTGAGAA GCTGACAGCA 
ACTCCAGCAA AGCCCACCAA GAGCGAGAAC GATGCCTCAT CCGAGAATGA GCAGCTGCTG 
AGCCGGAGCG TCGACAGTGA TGAGGAGCCC GCCCCTGACA AGCAGGGCTC CCCGGAGCTG 
TGCCTGCTGT CGCTGGTTCA CCTGGCCAGG GAGAAGTCTG CCACCAGCAA CAAGTCAGCC 
GGGATTCAAA GCCGGAGGAA AAAGATCCTC GATGTGTATG CCAACGTGTG TGGAGTCGTG 
GAAGGTCTTA GCCCCACGGA GCTGCCATTT GATTGCCTCG AGAAGACTAG CCGAATGCTC 
AGCTCCACGT ACAACTCTGA GAAGGCTGTT GTGAAAACGT GGCGCCACCT CGCCGAGAGC 
TTCGGCCTGA AGAGGGATGA GATTGGGGGC ATGACAGACG GCATGCAACT CTTTGACCGC 
ATCAGCACGG CAGGCTACAG CATCCCTGAG CTACTCACAA AACTGGTGCA GATTGAGCGG 
CTGGATGCTG TGGAGTCCTT GTGTGCAGAC ATACTGGAGT GGGCGGGGGT TGTGCCACCT 
GCCTCCCAGC CACATGCTGC ATCCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_071731.1
CDS	432..1778
Translation	MAHVGDCTQTPWLPVLVVSLMCSARAEYSNCGENEYYNQTTGLCQECPPCGPGEEPYLSCGYGTKDEDYGCVPCPAEKFSKGGYQICRRHKDCEGFFRATVLTPGDMENDAECGPCLPGYYMLENRPRNIYGMVCYSCLLAPPNTKECVGATSGASANFPGTSGSSTLSPFQHAHKELSGQGHLATALIIAMSTIFIMAIAIVLIIMFYILKTKPSAPACCTSHPGKSVEAQVSKDEEKKEAPDNVVMFSEKDEFEKLTATPAKPTKSENDASSENEQLLSRSVDSDEEPAPDKQGSPELCLLSLVHLAREKSATSNKSAGIQSRRKKILDVYANVCGVVEGLSPTELPFDCLEKTSRMLSSTYNSEKAVVKTWRHLAESFGLKRDEIGGMTDGMQLFDRISTAGYSIPELLTKLVQIERLDAVESLCADILEWAGVVPPASQPHAAS

Target ORF information:

RefSeq Version	NM_022336.3
Organism	Homo sapiens(human)
Definition	Homo sapiens ectodysplasin A receptor (EDAR), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_022336.3

ORF Insert Sequence:

ATGGCCCATG TGGGGGACTG CACGCAGACG CCCTGGCTCC CCGTCCTGGT GGTGTCTCTG 
ATGTGCTCAG CCCGAGCGGA ATACTCAAAC TGCGGTGAGA ACGAGTACTA CAACCAGACT 
ACGGGGCTGT GCCAGGAGTG CCCCCCGTGT GGGCCGGGAG AGGAGCCCTA CCTGTCCTGT 
GGCTACGGCA CCAAAGACGA GGACTACGGC TGCGTCCCCT GCCCGGCGGA GAAGTTTTCC 
AAAGGAGGCT ACCAGATATG CAGGCGTCAC AAAGACTGTG AGGGCTTCTT CCGGGCCACC 
GTGCTGACAC CAGGGGACAT GGAGAATGAC GCTGAGTGTG GCCCTTGCCT CCCTGGCTAC 
TACATGCTGG AGAACAGACC GAGGAACATC TATGGCATGG TCTGCTACTC CTGCCTCCTG 
GCACCCCCCA ACACCAAGGA ATGTGTGGGA GCCACTTCAG GAGCTTCTGC CAACTTCCCT 
GGCACCTCGG GCAGCAGCAC CCTGTCTCCC TTCCAGCACG CCCACAAAGA ACTCTCAGGC 
CAAGGACACC TGGCCACTGC CCTGATCATT GCAATGTCCA CCATCTTCAT CATGGCCATC 
GCCATCGTCC TCATCATCAT GTTCTACATC CTGAAGACAA AGCCCTCTGC CCCAGCCTGT 
TGCACCAGCC ACCCGGGGAA GAGCGTGGAG GCCCAAGTGA GCAAGGACGA GGAGAAGAAA 
GAGGCCCCAG ACAACGTGGT GATGTTCTCC GAGAAGGATG AATTTGAGAA GCTGACAGCA 
ACTCCAGCAA AGCCCACCAA GAGCGAGAAC GATGCCTCAT CCGAGAATGA GCAGCTGCTG 
AGCCGGAGCG TCGACAGTGA TGAGGAGCCC GCCCCTGACA AGCAGGGCTC CCCGGAGCTG 
TGCCTGCTGT CGCTGGTTCA CCTGGCCAGG GAGAAGTCTG CCACCAGCAA CAAGTCAGCC 
GGGATTCAAA GCCGGAGGAA AAAGATCCTC GATGTGTATG CCAACGTGTG TGGAGTCGTG 
GAAGGTCTTA GCCCCACGGA GCTGCCATTT GATTGCCTCG AGAAGACTAG CCGAATGCTC 
AGCTCCACGT ACAACTCTGA GAAGGCTGTT GTGAAAACGT GGCGCCACCT CGCCGAGAGC 
TTCGGCCTGA AGAGGGATGA GATTGGGGGC ATGACAGACG GCATGCAACT CTTTGACCGC 
ATCAGCACGG CAGGCTACAG CATCCCTGAG CTACTCACAA AACTGGTGCA GATTGAGCGG 
CTGGATGCTG TGGAGTCCTT GTGTGCAGAC ATACTGGAGT GGGCGGGGGT TGTGCCACCT 
GCCTCCCAGC CACATGCTGC ATCCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

EDAR ( XM_006712204.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_006712267.1 Homo sapiens ectodysplasin A receptor (EDAR), transcript variant X3, mRNA.

Price & Availability↑

CloneID	OHu35774
Clone ID Related Accession (Same CDS sequence)	XM_006712204.1
Accession Version	XM_006712204.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1443bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	tumor necrosis factor receptor superfamily member EDAR isoform X3
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000002.12) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGCCCATG TGGGGGACTG CACGCAGACG CCCTGGCTCC CCGTCCTGGT GGTGTCTCTG 
ATGTGCTCAG CCCGAGCGGA ATACTCAAAC TGCGGTGAGA ACGAGTACTA CAACCAGACT 
ACGGGGCTGT GCCAGGAGTG CCCCCCGTGT GGGCCGGGAG AGGAGCCCTA CCTGTCCTGT 
GGCTACGGCA CCAAAGACGA GGACTACGGC TGCGTCCCCT GCCCGGCGGA GAAGTTTTCC 
AAAGGAGGCT ACCAGATATG CAGGCGTCAC AAAGACTGTG AGGGCTTCTT CCGGGCCACC 
GTGCTGACAC CAGGGGACAT GGAGAATGAC GCTGAGTGTG GCCCTTGCCT CCCTGGCTAC 
TACATGCTGG AGAACAGACC GAGGAACATC TATGGCATGG TCTGCTACTC CTGCCTCCTG 
GCACCCCCCA ACACCAAGGA ATGTGTGGGA GCCACTTCAG GAGCTTCTGC CAACTTCCCT 
GGCACCTCGG GCAGCAGCAC CCTGTCTCCC TTCCAGCACG CCCACAAAGA ACTCTCAGGC 
CAAGGACACC TGGCCACTGC CCTGATCATT GCAATGTCCA CCATCTTCAT CATGGCCATC 
GCCATCGTCC TCATCATCAT GTTCTACATC CTGAAGACAA AGCCCTCTGC CCCAGGTGAC 
GGCCCCCATG CGCCGGTGCC CTGCTTCCTG GACTCTCCGT CAACTCCCCC TGTCGGAGAG 
CCTGGCTGCT CACTCCCTCC TCTCTCCCCA GCCTGTTGCA CCAGCCACCC GGGGAAGAGC 
GTGGAGGCCC AAGTGAGCAA GGACGAGGAG AAGAAAGAGG CCCCAGACAA CGTGGTGATG 
TTCTCCGAGA AGGATGAATT TGAGAAGCTG ACAGCAACTC CAGCAAAGCC CACCAAGAGC 
GAGAACGATG CCTCATCCGA GAATGAGCAG CTGCTGAGCC GGAGCGTCGA CAGTGATGAG 
GAGCCCGCCC CTGACAAGCA GGGCTCCCCG GAGCTGTGCC TGCTGTCGCT GGTTCACCTG 
GCCAGGGAGA AGTCTGCCAC CAGCAACAAG TCAGCCGGGA TTCAAAGCCG GAGGAAAAAG 
ATCCTCGATG TGTATGCCAA CGTGTGTGGA GTCGTGGAAG GTCTTAGCCC CACGGAGCTG 
CCATTTGATT GCCTCGAGAA GACTAGCCGA ATGCTCAGCT CCACGTACAA CTCTGAGAAG 
GCTGTTGTGA AAACGTGGCG CCACCTCGCC GAGAGCTTCG GCCTGAAGAG GGATGAGATT 
GGGGGCATGA CAGACGGCAT GCAACTCTTT GACCGCATCA GCACGGCAGG CTACAGCATC 
CCTGAGCTAC TCACAAAACT GGTGCAGATT GAGCGGCTGG ATGCTGTGGA GTCCTTGTGT 
GCAGACATAC TGGAGTGGGC GGGGGTTGTG CCACCTGCCT CCCAGCCACA TGCTGCATCC 
TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006712267.1
CDS	316..1758
Translation	MAHVGDCTQTPWLPVLVVSLMCSARAEYSNCGENEYYNQTTGLCQECPPCGPGEEPYLSCGYGTKDEDYGCVPCPAEKFSKGGYQICRRHKDCEGFFRATVLTPGDMENDAECGPCLPGYYMLENRPRNIYGMVCYSCLLAPPNTKECVGATSGASANFPGTSGSSTLSPFQHAHKELSGQGHLATALIIAMSTIFIMAIAIVLIIMFYILKTKPSAPGDGPHAPVPCFLDSPSTPPVGEPGCSLPPLSPACCTSHPGKSVEAQVSKDEEKKEAPDNVVMFSEKDEFEKLTATPAKPTKSENDASSENEQLLSRSVDSDEEPAPDKQGSPELCLLSLVHLAREKSATSNKSAGIQSRRKKILDVYANVCGVVEGLSPTELPFDCLEKTSRMLSSTYNSEKAVVKTWRHLAESFGLKRDEIGGMTDGMQLFDRISTAGYSIPELLTKLVQIERLDAVESLCADILEWAGVVPPASQPHAAS

Target ORF information:

RefSeq Version	XM_006712204.1
Organism	Homo sapiens(human)
Definition	Homo sapiens ectodysplasin A receptor (EDAR), transcript variant X3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006712204.1

ORF Insert Sequence:

ATGGCCCATG TGGGGGACTG CACGCAGACG CCCTGGCTCC CCGTCCTGGT GGTGTCTCTG 
ATGTGCTCAG CCCGAGCGGA ATACTCAAAC TGCGGTGAGA ACGAGTACTA CAACCAGACT 
ACGGGGCTGT GCCAGGAGTG CCCCCCGTGT GGGCCGGGAG AGGAGCCCTA CCTGTCCTGT 
GGCTACGGCA CCAAAGACGA GGACTACGGC TGCGTCCCCT GCCCGGCGGA GAAGTTTTCC 
AAAGGAGGCT ACCAGATATG CAGGCGTCAC AAAGACTGTG AGGGCTTCTT CCGGGCCACC 
GTGCTGACAC CAGGGGACAT GGAGAATGAC GCTGAGTGTG GCCCTTGCCT CCCTGGCTAC 
TACATGCTGG AGAACAGACC GAGGAACATC TATGGCATGG TCTGCTACTC CTGCCTCCTG 
GCACCCCCCA ACACCAAGGA ATGTGTGGGA GCCACTTCAG GAGCTTCTGC CAACTTCCCT 
GGCACCTCGG GCAGCAGCAC CCTGTCTCCC TTCCAGCACG CCCACAAAGA ACTCTCAGGC 
CAAGGACACC TGGCCACTGC CCTGATCATT GCAATGTCCA CCATCTTCAT CATGGCCATC 
GCCATCGTCC TCATCATCAT GTTCTACATC CTGAAGACAA AGCCCTCTGC CCCAGGTGAC 
GGCCCCCATG CGCCGGTGCC CTGCTTCCTG GACTCTCCGT CAACTCCCCC TGTCGGAGAG 
CCTGGCTGCT CACTCCCTCC TCTCTCCCCA GCCTGTTGCA CCAGCCACCC GGGGAAGAGC 
GTGGAGGCCC AAGTGAGCAA GGACGAGGAG AAGAAAGAGG CCCCAGACAA CGTGGTGATG 
TTCTCCGAGA AGGATGAATT TGAGAAGCTG ACAGCAACTC CAGCAAAGCC CACCAAGAGC 
GAGAACGATG CCTCATCCGA GAATGAGCAG CTGCTGAGCC GGAGCGTCGA CAGTGATGAG 
GAGCCCGCCC CTGACAAGCA GGGCTCCCCG GAGCTGTGCC TGCTGTCGCT GGTTCACCTG 
GCCAGGGAGA AGTCTGCCAC CAGCAACAAG TCAGCCGGGA TTCAAAGCCG GAGGAAAAAG 
ATCCTCGATG TGTATGCCAA CGTGTGTGGA GTCGTGGAAG GTCTTAGCCC CACGGAGCTG 
CCATTTGATT GCCTCGAGAA GACTAGCCGA ATGCTCAGCT CCACGTACAA CTCTGAGAAG 
GCTGTTGTGA AAACGTGGCG CCACCTCGCC GAGAGCTTCG GCCTGAAGAG GGATGAGATT 
GGGGGCATGA CAGACGGCAT GCAACTCTTT GACCGCATCA GCACGGCAGG CTACAGCATC 
CCTGAGCTAC TCACAAAACT GGTGCAGATT GAGCGGCTGG ATGCTGTGGA GTCCTTGTGT 
GCAGACATAC TGGAGTGGGC GGGGGTTGTG CCACCTGCCT CCCAGCCACA TGCTGCATCC 
TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

EDAR ( XM_011510503.2 ) cDNA ORF clone, Homo sapiens(human) -> XP_011508805.2 Homo sapiens ectodysplasin A receptor (EDAR), transcript variant X2, mRNA.

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CloneID	OHu88943
Clone ID Related Accession (Same CDS sequence)	XM_011510503.2
Accession Version	XM_011510503.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1491bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	tumor necrosis factor receptor superfamily member EDAR isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000002.12) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 6, 2016 this sequence version replaced XM_011510503.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGCACAGAG CAGTCACACC TCTCCTACAT CAAACCCCAA TTACTACACA CCCAGGGAAG 
GTGCCCAGCT CTCCCACTGC AGCAGTCACC CAAATGAGAA GGAAGGAGGC ATACAGACAC 
CCAAAGGTGA GCCCTTGGGA GAGGATGGCC CATGTGGGGG ACTGCACGCA GACGCCCTGG 
CTCCCCGTCC TGGTGGTGTC TCTGATGTGC TCAGCCCGAG CGGAATACTC AAACTGCGGT 
GAGAACGAGT ACTACAACCA GACTACGGGG CTGTGCCAGG AGTGCCCCCC GTGTGGGCCG 
GGAGAGGAGC CCTACCTGTC CTGTGGCTAC GGCACCAAAG ACGAGGACTA CGGCTGCGTC 
CCCTGCCCGG CGGAGAAGTT TTCCAAAGGA GGCTACCAGA TATGCAGGCG TCACAAAGAC 
TGTGAGGGCT TCTTCCGGGC CACCGTGCTG ACACCAGGGG ACATGGAGAA TGACGCTGAG 
TGTGGCCCTT GCCTCCCTGG CTACTACATG CTGGAGAACA GACCGAGGAA CATCTATGGC 
ATGGTCTGCT ACTCCTGCCT CCTGGCACCC CCCAACACCA AGGAATGTGT GGGAGCCACT 
TCAGGAGCTT CTGCCAACTT CCCTGGCACC TCGGGCAGCA GCACCCTGTC TCCCTTCCAG 
CACGCCCACA AAGAACTCTC AGGCCAAGGA CACCTGGCCA CTGCCCTGAT CATTGCAATG 
TCCACCATCT TCATCATGGC CATCGCCATC GTCCTCATCA TCATGTTCTA CATCCTGAAG 
ACAAAGCCCT CTGCCCCAGC CTGTTGCACC AGCCACCCGG GGAAGAGCGT GGAGGCCCAA 
GTGAGCAAGG ACGAGGAGAA GAAAGAGGCC CCAGACAACG TGGTGATGTT CTCCGAGAAG 
GATGAATTTG AGAAGCTGAC AGCAACTCCA GCAAAGCCCA CCAAGAGCGA GAACGATGCC 
TCATCCGAGA ATGAGCAGCT GCTGAGCCGG AGCGTCGACA GTGATGAGGA GCCCGCCCCT 
GACAAGCAGG GCTCCCCGGA GCTGTGCCTG CTGTCGCTGG TTCACCTGGC CAGGGAGAAG 
TCTGCCACCA GCAACAAGTC AGCCGGGATT CAAAGCCGGA GGAAAAAGAT CCTCGATGTG 
TATGCCAACG TGTGTGGAGT CGTGGAAGGT CTTAGCCCCA CGGAGCTGCC ATTTGATTGC 
CTCGAGAAGA CTAGCCGAAT GCTCAGCTCC ACGTACAACT CTGAGAAGGC TGTTGTGAAA 
ACGTGGCGCC ACCTCGCCGA GAGCTTCGGC CTGAAGAGGG ATGAGATTGG GGGCATGACA 
GACGGCATGC AACTCTTTGA CCGCATCAGC ACGGCAGGCT ACAGCATCCC TGAGCTACTC 
ACAAAACTGG TGCAGATTGA GCGGCTGGAT GCTGTGGAGT CCTTGTGTGC AGACATACTG 
GAGTGGGCGG GGGTTGTGCC ACCTGCCTCC CAGCCACATG CTGCATCCTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_011508805.2
CDS	44..1534
Translation	MHRAVTPLLHQTPITTHPGKVPSSPTAAVTQMRRKEAYRHPKVSPWERMAHVGDCTQTPWLPVLVVSLMCSARAEYSNCGENEYYNQTTGLCQECPPCGPGEEPYLSCGYGTKDEDYGCVPCPAEKFSKGGYQICRRHKDCEGFFRATVLTPGDMENDAECGPCLPGYYMLENRPRNIYGMVCYSCLLAPPNTKECVGATSGASANFPGTSGSSTLSPFQHAHKELSGQGHLATALIIAMSTIFIMAIAIVLIIMFYILKTKPSAPACCTSHPGKSVEAQVSKDEEKKEAPDNVVMFSEKDEFEKLTATPAKPTKSENDASSENEQLLSRSVDSDEEPAPDKQGSPELCLLSLVHLAREKSATSNKSAGIQSRRKKILDVYANVCGVVEGLSPTELPFDCLEKTSRMLSSTYNSEKAVVKTWRHLAESFGLKRDEIGGMTDGMQLFDRISTAGYSIPELLTKLVQIERLDAVESLCADILEWAGVVPPASQPHAAS

Target ORF information:

RefSeq Version	XM_011510503.2
Organism	Homo sapiens(human)
Definition	Homo sapiens ectodysplasin A receptor (EDAR), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011510503.2

ORF Insert Sequence:

ATGCACAGAG CAGTCACACC TCTCCTACAT CAAACCCCAA TTACTACACA CCCAGGGAAG 
GTGCCCAGCT CTCCCACTGC AGCAGTCACC CAAATGAGAA GGAAGGAGGC ATACAGACAC 
CCAAAGGTGA GCCCTTGGGA GAGGATGGCC CATGTGGGGG ACTGCACGCA GACGCCCTGG 
CTCCCCGTCC TGGTGGTGTC TCTGATGTGC TCAGCCCGAG CGGAATACTC AAACTGCGGT 
GAGAACGAGT ACTACAACCA GACTACGGGG CTGTGCCAGG AGTGCCCCCC GTGTGGGCCG 
GGAGAGGAGC CCTACCTGTC CTGTGGCTAC GGCACCAAAG ACGAGGACTA CGGCTGCGTC 
CCCTGCCCGG CGGAGAAGTT TTCCAAAGGA GGCTACCAGA TATGCAGGCG TCACAAAGAC 
TGTGAGGGCT TCTTCCGGGC CACCGTGCTG ACACCAGGGG ACATGGAGAA TGACGCTGAG 
TGTGGCCCTT GCCTCCCTGG CTACTACATG CTGGAGAACA GACCGAGGAA CATCTATGGC 
ATGGTCTGCT ACTCCTGCCT CCTGGCACCC CCCAACACCA AGGAATGTGT GGGAGCCACT 
TCAGGAGCTT CTGCCAACTT CCCTGGCACC TCGGGCAGCA GCACCCTGTC TCCCTTCCAG 
CACGCCCACA AAGAACTCTC AGGCCAAGGA CACCTGGCCA CTGCCCTGAT CATTGCAATG 
TCCACCATCT TCATCATGGC CATCGCCATC GTCCTCATCA TCATGTTCTA CATCCTGAAG 
ACAAAGCCCT CTGCCCCAGC CTGTTGCACC AGCCACCCGG GGAAGAGCGT GGAGGCCCAA 
GTGAGCAAGG ACGAGGAGAA GAAAGAGGCC CCAGACAACG TGGTGATGTT CTCCGAGAAG 
GATGAATTTG AGAAGCTGAC AGCAACTCCA GCAAAGCCCA CCAAGAGCGA GAACGATGCC 
TCATCCGAGA ATGAGCAGCT GCTGAGCCGG AGCGTCGACA GTGATGAGGA GCCCGCCCCT 
GACAAGCAGG GCTCCCCGGA GCTGTGCCTG CTGTCGCTGG TTCACCTGGC CAGGGAGAAG 
TCTGCCACCA GCAACAAGTC AGCCGGGATT CAAAGCCGGA GGAAAAAGAT CCTCGATGTG 
TATGCCAACG TGTGTGGAGT CGTGGAAGGT CTTAGCCCCA CGGAGCTGCC ATTTGATTGC 
CTCGAGAAGA CTAGCCGAAT GCTCAGCTCC ACGTACAACT CTGAGAAGGC TGTTGTGAAA 
ACGTGGCGCC ACCTCGCCGA GAGCTTCGGC CTGAAGAGGG ATGAGATTGG GGGCATGACA 
GACGGCATGC AACTCTTTGA CCGCATCAGC ACGGCAGGCT ACAGCATCCC TGAGCTACTC 
ACAAAACTGG TGCAGATTGA GCGGCTGGAT GCTGTGGAGT CCTTGTGTGC AGACATACTG 
GAGTGGGCGG GGGTTGTGCC ACCTGCCTCC CAGCCACATG CTGCATCCTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

EDAR ( XM_011510502.2 ) cDNA ORF clone, Homo sapiens(human) -> XP_011508804.2 Homo sapiens ectodysplasin A receptor (EDAR), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OHu88942
Clone ID Related Accession (Same CDS sequence)	XM_011510502.2
Accession Version	XM_011510502.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1587bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	tumor necrosis factor receptor superfamily member EDAR isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000002.12) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 6, 2016 this sequence version replaced XM_011510502.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGCACAGAG CAGTCACACC TCTCCTACAT CAAACCCCAA TTACTACACA CCCAGGGAAG 
GTGCCCAGCT CTCCCACTGC AGCAGTCACC CAAATGAGAA GGAAGGAGGC ATACAGACAC 
CCAAAGGTGA GCCCTTGGGA GAGGATGGCC CATGTGGGGG ACTGCACGCA GACGCCCTGG 
CTCCCCGTCC TGGTGGTGTC TCTGATGTGC TCAGCCCGAG CGGAATACTC AAACTGCGGT 
GAGAACGAGT ACTACAACCA GACTACGGGG CTGTGCCAGG AGTGCCCCCC GTGTGGGCCG 
GGAGAGGAGC CCTACCTGTC CTGTGGCTAC GGCACCAAAG ACGAGGACTA CGGCTGCGTC 
CCCTGCCCGG CGGAGAAGTT TTCCAAAGGA GGCTACCAGA TATGCAGGCG TCACAAAGAC 
TGTGAGGGCT TCTTCCGGGC CACCGTGCTG ACACCAGGGG ACATGGAGAA TGACGCTGAG 
TGTGGCCCTT GCCTCCCTGG CTACTACATG CTGGAGAACA GACCGAGGAA CATCTATGGC 
ATGGTCTGCT ACTCCTGCCT CCTGGCACCC CCCAACACCA AGGAATGTGT GGGAGCCACT 
TCAGGAGCTT CTGCCAACTT CCCTGGCACC TCGGGCAGCA GCACCCTGTC TCCCTTCCAG 
CACGCCCACA AAGAACTCTC AGGCCAAGGA CACCTGGCCA CTGCCCTGAT CATTGCAATG 
TCCACCATCT TCATCATGGC CATCGCCATC GTCCTCATCA TCATGTTCTA CATCCTGAAG 
ACAAAGCCCT CTGCCCCAGG TGACGGCCCC CATGCGCCGG TGCCCTGCTT CCTGGACTCT 
CCGTCAACTC CCCCTGTCGG AGAGCCTGGC TGCTCACTCC CTCCTCTCTC CCCAGCCTGT 
TGCACCAGCC ACCCGGGGAA GAGCGTGGAG GCCCAAGTGA GCAAGGACGA GGAGAAGAAA 
GAGGCCCCAG ACAACGTGGT GATGTTCTCC GAGAAGGATG AATTTGAGAA GCTGACAGCA 
ACTCCAGCAA AGCCCACCAA GAGCGAGAAC GATGCCTCAT CCGAGAATGA GCAGCTGCTG 
AGCCGGAGCG TCGACAGTGA TGAGGAGCCC GCCCCTGACA AGCAGGGCTC CCCGGAGCTG 
TGCCTGCTGT CGCTGGTTCA CCTGGCCAGG GAGAAGTCTG CCACCAGCAA CAAGTCAGCC 
GGGATTCAAA GCCGGAGGAA AAAGATCCTC GATGTGTATG CCAACGTGTG TGGAGTCGTG 
GAAGGTCTTA GCCCCACGGA GCTGCCATTT GATTGCCTCG AGAAGACTAG CCGAATGCTC 
AGCTCCACGT ACAACTCTGA GAAGGCTGTT GTGAAAACGT GGCGCCACCT CGCCGAGAGC 
TTCGGCCTGA AGAGGGATGA GATTGGGGGC ATGACAGACG GCATGCAACT CTTTGACCGC 
ATCAGCACGG CAGGCTACAG CATCCCTGAG CTACTCACAA AACTGGTGCA GATTGAGCGG 
CTGGATGCTG TGGAGTCCTT GTGTGCAGAC ATACTGGAGT GGGCGGGGGT TGTGCCACCT 
GCCTCCCAGC CACATGCTGC ATCCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_011508804.2
CDS	51..1637
Translation	MHRAVTPLLHQTPITTHPGKVPSSPTAAVTQMRRKEAYRHPKVSPWERMAHVGDCTQTPWLPVLVVSLMCSARAEYSNCGENEYYNQTTGLCQECPPCGPGEEPYLSCGYGTKDEDYGCVPCPAEKFSKGGYQICRRHKDCEGFFRATVLTPGDMENDAECGPCLPGYYMLENRPRNIYGMVCYSCLLAPPNTKECVGATSGASANFPGTSGSSTLSPFQHAHKELSGQGHLATALIIAMSTIFIMAIAIVLIIMFYILKTKPSAPGDGPHAPVPCFLDSPSTPPVGEPGCSLPPLSPACCTSHPGKSVEAQVSKDEEKKEAPDNVVMFSEKDEFEKLTATPAKPTKSENDASSENEQLLSRSVDSDEEPAPDKQGSPELCLLSLVHLAREKSATSNKSAGIQSRRKKILDVYANVCGVVEGLSPTELPFDCLEKTSRMLSSTYNSEKAVVKTWRHLAESFGLKRDEIGGMTDGMQLFDRISTAGYSIPELLTKLVQIERLDAVESLCADILEWAGVVPPASQPHAAS

Target ORF information:

RefSeq Version	XM_011510502.2
Organism	Homo sapiens(human)
Definition	Homo sapiens ectodysplasin A receptor (EDAR), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011510502.2

ORF Insert Sequence:

ATGCACAGAG CAGTCACACC TCTCCTACAT CAAACCCCAA TTACTACACA CCCAGGGAAG 
GTGCCCAGCT CTCCCACTGC AGCAGTCACC CAAATGAGAA GGAAGGAGGC ATACAGACAC 
CCAAAGGTGA GCCCTTGGGA GAGGATGGCC CATGTGGGGG ACTGCACGCA GACGCCCTGG 
CTCCCCGTCC TGGTGGTGTC TCTGATGTGC TCAGCCCGAG CGGAATACTC AAACTGCGGT 
GAGAACGAGT ACTACAACCA GACTACGGGG CTGTGCCAGG AGTGCCCCCC GTGTGGGCCG 
GGAGAGGAGC CCTACCTGTC CTGTGGCTAC GGCACCAAAG ACGAGGACTA CGGCTGCGTC 
CCCTGCCCGG CGGAGAAGTT TTCCAAAGGA GGCTACCAGA TATGCAGGCG TCACAAAGAC 
TGTGAGGGCT TCTTCCGGGC CACCGTGCTG ACACCAGGGG ACATGGAGAA TGACGCTGAG 
TGTGGCCCTT GCCTCCCTGG CTACTACATG CTGGAGAACA GACCGAGGAA CATCTATGGC 
ATGGTCTGCT ACTCCTGCCT CCTGGCACCC CCCAACACCA AGGAATGTGT GGGAGCCACT 
TCAGGAGCTT CTGCCAACTT CCCTGGCACC TCGGGCAGCA GCACCCTGTC TCCCTTCCAG 
CACGCCCACA AAGAACTCTC AGGCCAAGGA CACCTGGCCA CTGCCCTGAT CATTGCAATG 
TCCACCATCT TCATCATGGC CATCGCCATC GTCCTCATCA TCATGTTCTA CATCCTGAAG 
ACAAAGCCCT CTGCCCCAGG TGACGGCCCC CATGCGCCGG TGCCCTGCTT CCTGGACTCT 
CCGTCAACTC CCCCTGTCGG AGAGCCTGGC TGCTCACTCC CTCCTCTCTC CCCAGCCTGT 
TGCACCAGCC ACCCGGGGAA GAGCGTGGAG GCCCAAGTGA GCAAGGACGA GGAGAAGAAA 
GAGGCCCCAG ACAACGTGGT GATGTTCTCC GAGAAGGATG AATTTGAGAA GCTGACAGCA 
ACTCCAGCAA AGCCCACCAA GAGCGAGAAC GATGCCTCAT CCGAGAATGA GCAGCTGCTG 
AGCCGGAGCG TCGACAGTGA TGAGGAGCCC GCCCCTGACA AGCAGGGCTC CCCGGAGCTG 
TGCCTGCTGT CGCTGGTTCA CCTGGCCAGG GAGAAGTCTG CCACCAGCAA CAAGTCAGCC 
GGGATTCAAA GCCGGAGGAA AAAGATCCTC GATGTGTATG CCAACGTGTG TGGAGTCGTG 
GAAGGTCTTA GCCCCACGGA GCTGCCATTT GATTGCCTCG AGAAGACTAG CCGAATGCTC 
AGCTCCACGT ACAACTCTGA GAAGGCTGTT GTGAAAACGT GGCGCCACCT CGCCGAGAGC 
TTCGGCCTGA AGAGGGATGA GATTGGGGGC ATGACAGACG GCATGCAACT CTTTGACCGC 
ATCAGCACGG CAGGCTACAG CATCCCTGAG CTACTCACAA AACTGGTGCA GATTGAGCGG 
CTGGATGCTG TGGAGTCCTT GTGTGCAGAC ATACTGGAGT GGGCGGGGGT TGTGCCACCT 
GCCTCCCAGC CACATGCTGC ATCCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Evolutionary significance of selected EDAR variants in Tibetan high-altitude adaptations.
Science China. Life sciences(2017 Aug)
Shao J,Raza MS,Zhuoma B,Zeng C

Mutational spectrum of EDA and EDAR genes in a cohort of Mexican mestizo patients with hypohidrotic ectodermal dysplasia.
Journal of the European Academy of Dermatology and Venereology : JEADV31(7)e321-e324(2017 Jul)
Monroy-Jaramillo N,Abad-Flores JD,Garc?a-Delgado C,Villase?or-Dom?nguez A,Mena-Cedillos C,Toledo-Bahena ME,Valencia-Herrera AM,S?nchez-Boiso A,Akaki-Carre?o YI,Del R?o Navarro B,Aguirre-Hern?ndez J,L?pez-L?pez M,Cervantes A,Cerb?n M,Mor?n-Barroso VF

Association between EDAR Polymorphisms and Non-Syndromic Tooth Agenesis in the Chinese Han Population.
The Chinese journal of dental research : the official journal of the Scientific Section of the Chinese Stomatological Association (CSA)20(3)153-159(2017)
Chen YT,Liu HC,Han D,Liu Y,Feng HL

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EDAR cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

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Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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