MASP2 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	MASP2
Entrez Gene ID	10747
Full Name	mannan binding lectin serine peptidase 2
Synonyms	MAP19,MASP-2,MASP1P1,sMAP
General protein information	Preferred Names mannan binding lectin serine peptidase 2 Names mannan-binding lectin serine protease 2 MBL-associated plasma protein of 19 kD MBL-associated serine protease 2 mannan-binding lectin serine peptidase 1 pseudogene 1 mannan-binding lectin serine protease 1 pseudogene 1 mannose-binding protein-associated serine protease 2 small MBL-associated protein
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 1 Map Location: 1p36.22
Summary	This gene encodes a member of the peptidase S1 family of serine proteases. The encoded preproprotein is proteolytically processed to generate A and B chains that heterodimerize to form the mature protease. This protease cleaves complement components C2 and C4 in order to generate C3 convertase in the lectin pathway of the complement system. The encoded protease also plays a role in the coagulation cascade through cleavage of prothrombin to form thrombin. Myocardial infarction and acute stroke patients exhibit reduced serum concentrations of the encoded protein. Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed. [provided by RefSeq, Feb 2016].
Disorder MIM:	605102
Disorder Html:	MASP2 deficiency, 613791 (3)

mRNA and Protein(s)

mRNA	Protein	Name
NM_006610.3	NP_006601.2	mannan-binding lectin serine protease 2 isoform 1 preproprotein
NM_006610.4	NP_006601.2	mannan-binding lectin serine protease 2 isoform 1 preproprotein
NM_139208.2	NP_631947.1	mannan-binding lectin serine protease 2 isoform 2 precursor
XM_017000097.1	XP_016855586.1	mannan-binding lectin serine protease 2 isoform X1
NM_139208.3	NP_631947.1	mannan-binding lectin serine protease 2 isoform 2 precursor

Pathways from BioSystems

Homologies

Canis lupus familiaris (dog)	MASP2	XP_544572.4
Bos taurus (cattle)	MASP2	NP_001179001.1
Xenopus tropicalis (tropical clawed frog)	masp2	NP_001011037.1
Mus musculus (house mouse)	Masp2	NP_001003893.1
Rattus norvegicus (Norway rat)	Masp2	NP_742040.1
Homo sapiens (human)	MASP2	NP_006601.2
Pan troglodytes (chimpanzee)	MASP2	XP_001135757.2
Gallus gallus (chicken)	MASP2	NP_998752.1
Danio rerio (zebrafish)	masp2	NP_001116330.1

Gene Ontology
Bibliography

Related articles in PubMed

Serine proteases of the complement lectin pathway and their genetic variations in ischaemic stroke.
Tsakanova G, Stepanyan A, Nahapetyan K, Sim RB, Arakelyan A, Boyajyan A
Journal of clinical pathology71(2)141-147(2018 Feb)

Incident microalbuminuria and complement factor mannan-binding lectin-associated protein 19 in people with newly diagnosed type 1 diabetes.
?stergaard JA, Thiel S, Hoffmann-Petersen IT, Hovind P, Parving HH, Tarnow L, Rossing P, Hansen TK
Diabetes/metabolism research and reviews33(5)(2017 Jul)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The results of this study show that MASP-2 contributes to severity and outcome in pneumococcal meningitis. In patients with pneumococcal meningitis, MASP-2 concentration was elevated in the CSF and high levels were associated with poor functional outcome.
Title: Mannose-binding lectin-associated serine protease 2 (MASP-2) contributes to poor disease outcome in humans and mice with pneumococcal meningitis.

This is the first comprehensive meta-analysis indicates that the MASP-2 functional gene (rs72550870) polymorphism is not associated with the infection diseases, and the key functional gene polymorphism of rs72550870 did not increase susceptibility to the infection diseases.
Title: Association between MASP-2 gene polymorphism and risk of infection diseases: A meta-analysis.

This study suggests that hMASP-2 can induce a protective efficacy in BCG-infected rabbit skin models, which affects both the progress of lesions and the survival of the mycobacteria within them.
Title: Effects of MBL-associated serine protease-2 (MASP-2) on liquefaction and ulceration in rabbit skin model of tuberculosis.

Genetically determined MASP-2 levels seem to have a two-edge effect in HIV and probably HCV/HBV coinfection, whereas low levels increase the susceptibility to infection, but on the other side protects against AIDS.
Title: A dual role for Mannan-binding lectin-associated serine protease 2 (MASP-2) in HIV infection.

The ficolin-3/MASP-2 complex was significantly lower in the cardiac syndrome X patients compared to controls.
Title: Association of Low Ficolin-Lectin Pathway Parameters with Cardiac Syndrome X.

The following MASP2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the MASP2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu17812	NM_006610.4 Latest version!	Homo sapiens mannan binding lectin serine peptidase 2 (MASP2), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$344.50-$482.30 $689.00
OHu14847	NM_139208.3 Latest version!	Homo sapiens mannan binding lectin serine peptidase 2 (MASP2), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$69.30 $99.00
OHu83031	XM_017000097.1 Latest version!	Homo sapiens mannan binding lectin serine peptidase 2 (MASP2), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$139.30 $199.00
View Old Accession Versions >>
OHu17812	NM_006610.3	Homo sapiens mannan binding lectin serine peptidase 2 (MASP2), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$344.50-$482.30 $689.00
OHu14847	NM_139208.2	Homo sapiens mannan binding lectin serine peptidase 2 (MASP2), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$69.30 $99.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

MASP2 ( NM_006610.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_006601.2 Homo sapiens mannan binding lectin serine peptidase 2 (MASP2), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu17812
Clone ID Related Accession (Same CDS sequence)	NM_006610.3 , NM_006610.4
Accession Version	NM_006610.3	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2061bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-02-22
Organism	Homo sapiens(human)
Product	mannan-binding lectin serine protease 2 isoform 1 preproprotein
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AK290823.1 and Y09926.1. This sequence is a reference standard in the RefSeqGene project. On Feb 26, 2011 this sequence version replaced NM_006610.2. Transcript Variant: This variant (1) is the longer transcript and encodes isoform 1 which activates complement component 4. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: Y09926.1, X98400.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA2142680, SAMEA2145122 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGAGGCTGC TGACCCTCCT GGGCCTTCTG TGTGGCTCGG TGGCCACCCC CTTGGGCCCG 
AAGTGGCCTG AACCTGTGTT CGGGCGCCTG GCATCCCCCG GCTTTCCAGG GGAGTATGCC 
AATGACCAGG AGCGGCGCTG GACCCTGACT GCACCCCCCG GCTACCGCCT GCGCCTCTAC 
TTCACCCACT TCGACCTGGA GCTCTCCCAC CTCTGCGAGT ACGACTTCGT CAAGCTGAGC 
TCGGGGGCCA AGGTGCTGGC CACGCTGTGC GGGCAGGAGA GCACAGACAC GGAGCGGGCC 
CCTGGCAAGG ACACTTTCTA CTCGCTGGGC TCCAGCCTGG ACATTACCTT CCGCTCCGAC 
TACTCCAACG AGAAGCCGTT CACGGGGTTC GAGGCCTTCT ATGCAGCCGA GGACATTGAC 
GAGTGCCAGG TGGCCCCGGG AGAGGCGCCC ACCTGCGACC ACCACTGCCA CAACCACCTG 
GGCGGTTTCT ACTGCTCCTG CCGCGCAGGC TACGTCCTGC ACCGTAACAA GCGCACCTGC 
TCAGCCCTGT GCTCCGGCCA GGTCTTCACC CAGAGGTCTG GGGAGCTCAG CAGCCCTGAA 
TACCCACGGC CGTATCCCAA ACTCTCCAGT TGCACTTACA GCATCAGCCT GGAGGAGGGG 
TTCAGTGTCA TTCTGGACTT TGTGGAGTCC TTCGATGTGG AGACACACCC TGAAACCCTG 
TGTCCCTACG ACTTTCTCAA GATTCAAACA GACAGAGAAG AACATGGCCC ATTCTGTGGG 
AAGACATTGC CCCACAGGAT TGAAACAAAA AGCAACACGG TGACCATCAC CTTTGTCACA 
GATGAATCAG GAGACCACAC AGGCTGGAAG ATCCACTACA CGAGCACAGC GCAGCCTTGC 
CCTTATCCGA TGGCGCCACC TAATGGCCAC GTTTCACCTG TGCAAGCCAA ATACATCCTG 
AAAGACAGCT TCTCCATCTT TTGCGAGACT GGCTATGAGC TTCTGCAAGG TCACTTGCCC 
CTGAAATCCT TTACTGCAGT TTGTCAGAAA GATGGATCTT GGGACCGGCC AATGCCCGCG 
TGCAGCATTG TTGACTGTGG CCCTCCTGAT GATCTACCCA GTGGCCGAGT GGAGTACATC 
ACAGGTCCTG GAGTGACCAC CTACAAAGCT GTGATTCAGT ACAGCTGTGA AGAGACCTTC 
TACACAATGA AAGTGAATGA TGGTAAATAT GTGTGTGAGG CTGATGGATT CTGGACGAGC 
TCCAAAGGAG AAAAATCACT CCCAGTCTGT GAGCCTGTTT GTGGACTATC AGCCCGCACA 
ACAGGAGGGC GTATATATGG AGGGCAAAAG GCAAAACCTG GTGATTTTCC TTGGCAAGTC 
CTGATATTAG GTGGAACCAC AGCAGCAGGT GCACTTTTAT ATGACAACTG GGTCCTAACA 
GCTGCTCATG CCGTCTATGA GCAAAAACAT GATGCATCCG CCCTGGACAT TCGAATGGGC 
ACCCTGAAAA GACTATCACC TCATTATACA CAAGCCTGGT CTGAAGCTGT TTTTATACAT 
GAAGGTTATA CTCATGATGC TGGCTTTGAC AATGACATAG CACTGATTAA ATTGAATAAC 
AAAGTTGTAA TCAATAGCAA CATCACGCCT ATTTGTCTGC CAAGAAAAGA AGCTGAATCC 
TTTATGAGGA CAGATGACAT TGGAACTGCA TCTGGATGGG GATTAACCCA AAGGGGTTTT 
CTTGCTAGAA ATCTAATGTA TGTCGACATA CCGATTGTTG ACCATCAAAA ATGTACTGCT 
GCATATGAAA AGCCACCCTA TCCAAGGGGA AGTGTAACTG CTAACATGCT TTGTGCTGGC 
TTAGAAAGTG GGGGCAAGGA CAGCTGCAGA GGTGACAGCG GAGGGGCACT GGTGTTTCTA 
GATAGTGAAA CAGAGAGGTG GTTTGTGGGA GGAATAGTGT CCTGGGGTTC CATGAATTGT 
GGGGAAGCAG GTCAGTATGG AGTCTACACA AAAGTTATTA ACTATATTCC CTGGATCGAG 
AACATAATTA GTGATTTTTA A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_006601.2
CDS	33..2093
Translation	MRLLTLLGLLCGSVATPLGPKWPEPVFGRLASPGFPGEYANDQERRWTLTAPPGYRLRLYFTHFDLELSHLCEYDFVKLSSGAKVLATLCGQESTDTERAPGKDTFYSLGSSLDITFRSDYSNEKPFTGFEAFYAAEDIDECQVAPGEAPTCDHHCHNHLGGFYCSCRAGYVLHRNKRTCSALCSGQVFTQRSGELSSPEYPRPYPKLSSCTYSISLEEGFSVILDFVESFDVETHPETLCPYDFLKIQTDREEHGPFCGKTLPHRIETKSNTVTITFVTDESGDHTGWKIHYTSTAQPCPYPMAPPNGHVSPVQAKYILKDSFSIFCETGYELLQGHLPLKSFTAVCQKDGSWDRPMPACSIVDCGPPDDLPSGRVEYITGPGVTTYKAVIQYSCEETFYTMKVNDGKYVCEADGFWTSSKGEKSLPVCEPVCGLSARTTGGRIYGGQKAKPGDFPWQVLILGGTTAAGALLYDNWVLTAAHAVYEQKHDASALDIRMGTLKRLSPHYTQAWSEAVFIHEGYTHDAGFDNDIALIKLNNKVVINSNITPICLPRKEAESFMRTDDIGTASGWGLTQRGFLARNLMYVDIPIVDHQKCTAAYEKPPYPRGSVTANMLCAGLESGGKDSCRGDSGGALVFLDSETERWFVGGIVSWGSMNCGEAGQYGVYTKVINYIPWIENIISDF

Target ORF information:

RefSeq Version	NM_006610.3
Organism	Homo sapiens(human)
Definition	Homo sapiens mannan binding lectin serine peptidase 2 (MASP2), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_006610.3

ORF Insert Sequence:

ATGAGGCTGC TGACCCTCCT GGGCCTTCTG TGTGGCTCGG TGGCCACCCC CTTGGGCCCG 
AAGTGGCCTG AACCTGTGTT CGGGCGCCTG GCATCCCCCG GCTTTCCAGG GGAGTATGCC 
AATGACCAGG AGCGGCGCTG GACCCTGACT GCACCCCCCG GCTACCGCCT GCGCCTCTAC 
TTCACCCACT TCGACCTGGA GCTCTCCCAC CTCTGCGAGT ACGACTTCGT CAAGCTGAGC 
TCGGGGGCCA AGGTGCTGGC CACGCTGTGC GGGCAGGAGA GCACAGACAC GGAGCGGGCC 
CCTGGCAAGG ACACTTTCTA CTCGCTGGGC TCCAGCCTGG ACATTACCTT CCGCTCCGAC 
TACTCCAACG AGAAGCCGTT CACGGGGTTC GAGGCCTTCT ATGCAGCCGA GGACATTGAC 
GAGTGCCAGG TGGCCCCGGG AGAGGCGCCC ACCTGCGACC ACCACTGCCA CAACCACCTG 
GGCGGTTTCT ACTGCTCCTG CCGCGCAGGC TACGTCCTGC ACCGTAACAA GCGCACCTGC 
TCAGCCCTGT GCTCCGGCCA GGTCTTCACC CAGAGGTCTG GGGAGCTCAG CAGCCCTGAA 
TACCCACGGC CGTATCCCAA ACTCTCCAGT TGCACTTACA GCATCAGCCT GGAGGAGGGG 
TTCAGTGTCA TTCTGGACTT TGTGGAGTCC TTCGATGTGG AGACACACCC TGAAACCCTG 
TGTCCCTACG ACTTTCTCAA GATTCAAACA GACAGAGAAG AACATGGCCC ATTCTGTGGG 
AAGACATTGC CCCACAGGAT TGAAACAAAA AGCAACACGG TGACCATCAC CTTTGTCACA 
GATGAATCAG GAGACCACAC AGGCTGGAAG ATCCACTACA CGAGCACAGC GCAGCCTTGC 
CCTTATCCGA TGGCGCCACC TAATGGCCAC GTTTCACCTG TGCAAGCCAA ATACATCCTG 
AAAGACAGCT TCTCCATCTT TTGCGAGACT GGCTATGAGC TTCTGCAAGG TCACTTGCCC 
CTGAAATCCT TTACTGCAGT TTGTCAGAAA GATGGATCTT GGGACCGGCC AATGCCCGCG 
TGCAGCATTG TTGACTGTGG CCCTCCTGAT GATCTACCCA GTGGCCGAGT GGAGTACATC 
ACAGGTCCTG GAGTGACCAC CTACAAAGCT GTGATTCAGT ACAGCTGTGA AGAGACCTTC 
TACACAATGA AAGTGAATGA TGGTAAATAT GTGTGTGAGG CTGATGGATT CTGGACGAGC 
TCCAAAGGAG AAAAATCACT CCCAGTCTGT GAGCCTGTTT GTGGACTATC AGCCCGCACA 
ACAGGAGGGC GTATATATGG AGGGCAAAAG GCAAAACCTG GTGATTTTCC TTGGCAAGTC 
CTGATATTAG GTGGAACCAC AGCAGCAGGT GCACTTTTAT ATGACAACTG GGTCCTAACA 
GCTGCTCATG CCGTCTATGA GCAAAAACAT GATGCATCCG CCCTGGACAT TCGAATGGGC 
ACCCTGAAAA GACTATCACC TCATTATACA CAAGCCTGGT CTGAAGCTGT TTTTATACAT 
GAAGGTTATA CTCATGATGC TGGCTTTGAC AATGACATAG CACTGATTAA ATTGAATAAC 
AAAGTTGTAA TCAATAGCAA CATCACGCCT ATTTGTCTGC CAAGAAAAGA AGCTGAATCC 
TTTATGAGGA CAGATGACAT TGGAACTGCA TCTGGATGGG GATTAACCCA AAGGGGTTTT 
CTTGCTAGAA ATCTAATGTA TGTCGACATA CCGATTGTTG ACCATCAAAA ATGTACTGCT 
GCATATGAAA AGCCACCCTA TCCAAGGGGA AGTGTAACTG CTAACATGCT TTGTGCTGGC 
TTAGAAAGTG GGGGCAAGGA CAGCTGCAGA GGTGACAGCG GAGGGGCACT GGTGTTTCTA 
GATAGTGAAA CAGAGAGGTG GTTTGTGGGA GGAATAGTGT CCTGGGGTTC CATGAATTGT 
GGGGAAGCAG GTCAGTATGG AGTCTACACA AAAGTTATTA ACTATATTCC CTGGATCGAG 
AACATAATTA GTGATTTTTA A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

MASP2 ( NM_006610.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_006601.2 Homo sapiens mannan binding lectin serine peptidase 2 (MASP2), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu17812
Clone ID Related Accession (Same CDS sequence)	NM_006610.3 , NM_006610.4
Accession Version	NM_006610.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2061bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2020-01-01
Organism	Homo sapiens(human)
Product	mannan-binding lectin serine protease 2 isoform 1 preproprotein
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AK290823.1 and Y09926.1. This sequence is a reference standard in the RefSeqGene project. On May 17, 2019 this sequence version replaced NM_006610.3. Transcript Variant: This variant (1) is the longer transcript and encodes isoform 1 which activates complement component 4. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: Y09926.1, AK290823.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA2142680, SAMEA2145122 [ECO:0000350] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000400897.8/ ENSP00000383690.3 RefSeq Select criteria :: based on conservation, expression, longest protein ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGAGGCTGC TGACCCTCCT GGGCCTTCTG TGTGGCTCGG TGGCCACCCC CTTGGGCCCG 
AAGTGGCCTG AACCTGTGTT CGGGCGCCTG GCATCCCCCG GCTTTCCAGG GGAGTATGCC 
AATGACCAGG AGCGGCGCTG GACCCTGACT GCACCCCCCG GCTACCGCCT GCGCCTCTAC 
TTCACCCACT TCGACCTGGA GCTCTCCCAC CTCTGCGAGT ACGACTTCGT CAAGCTGAGC 
TCGGGGGCCA AGGTGCTGGC CACGCTGTGC GGGCAGGAGA GCACAGACAC GGAGCGGGCC 
CCTGGCAAGG ACACTTTCTA CTCGCTGGGC TCCAGCCTGG ACATTACCTT CCGCTCCGAC 
TACTCCAACG AGAAGCCGTT CACGGGGTTC GAGGCCTTCT ATGCAGCCGA GGACATTGAC 
GAGTGCCAGG TGGCCCCGGG AGAGGCGCCC ACCTGCGACC ACCACTGCCA CAACCACCTG 
GGCGGTTTCT ACTGCTCCTG CCGCGCAGGC TACGTCCTGC ACCGTAACAA GCGCACCTGC 
TCAGCCCTGT GCTCCGGCCA GGTCTTCACC CAGAGGTCTG GGGAGCTCAG CAGCCCTGAA 
TACCCACGGC CGTATCCCAA ACTCTCCAGT TGCACTTACA GCATCAGCCT GGAGGAGGGG 
TTCAGTGTCA TTCTGGACTT TGTGGAGTCC TTCGATGTGG AGACACACCC TGAAACCCTG 
TGTCCCTACG ACTTTCTCAA GATTCAAACA GACAGAGAAG AACATGGCCC ATTCTGTGGG 
AAGACATTGC CCCACAGGAT TGAAACAAAA AGCAACACGG TGACCATCAC CTTTGTCACA 
GATGAATCAG GAGACCACAC AGGCTGGAAG ATCCACTACA CGAGCACAGC GCAGCCTTGC 
CCTTATCCGA TGGCGCCACC TAATGGCCAC GTTTCACCTG TGCAAGCCAA ATACATCCTG 
AAAGACAGCT TCTCCATCTT TTGCGAGACT GGCTATGAGC TTCTGCAAGG TCACTTGCCC 
CTGAAATCCT TTACTGCAGT TTGTCAGAAA GATGGATCTT GGGACCGGCC AATGCCCGCG 
TGCAGCATTG TTGACTGTGG CCCTCCTGAT GATCTACCCA GTGGCCGAGT GGAGTACATC 
ACAGGTCCTG GAGTGACCAC CTACAAAGCT GTGATTCAGT ACAGCTGTGA AGAGACCTTC 
TACACAATGA AAGTGAATGA TGGTAAATAT GTGTGTGAGG CTGATGGATT CTGGACGAGC 
TCCAAAGGAG AAAAATCACT CCCAGTCTGT GAGCCTGTTT GTGGACTATC AGCCCGCACA 
ACAGGAGGGC GTATATATGG AGGGCAAAAG GCAAAACCTG GTGATTTTCC TTGGCAAGTC 
CTGATATTAG GTGGAACCAC AGCAGCAGGT GCACTTTTAT ATGACAACTG GGTCCTAACA 
GCTGCTCATG CCGTCTATGA GCAAAAACAT GATGCATCCG CCCTGGACAT TCGAATGGGC 
ACCCTGAAAA GACTATCACC TCATTATACA CAAGCCTGGT CTGAAGCTGT TTTTATACAT 
GAAGGTTATA CTCATGATGC TGGCTTTGAC AATGACATAG CACTGATTAA ATTGAATAAC 
AAAGTTGTAA TCAATAGCAA CATCACGCCT ATTTGTCTGC CAAGAAAAGA AGCTGAATCC 
TTTATGAGGA CAGATGACAT TGGAACTGCA TCTGGATGGG GATTAACCCA AAGGGGTTTT 
CTTGCTAGAA ATCTAATGTA TGTCGACATA CCGATTGTTG ACCATCAAAA ATGTACTGCT 
GCATATGAAA AGCCACCCTA TCCAAGGGGA AGTGTAACTG CTAACATGCT TTGTGCTGGC 
TTAGAAAGTG GGGGCAAGGA CAGCTGCAGA GGTGACAGCG GAGGGGCACT GGTGTTTCTA 
GATAGTGAAA CAGAGAGGTG GTTTGTGGGA GGAATAGTGT CCTGGGGTTC CATGAATTGT 
GGGGAAGCAG GTCAGTATGG AGTCTACACA AAAGTTATTA ACTATATTCC CTGGATCGAG 
AACATAATTA GTGATTTTTA A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_006601.2
CDS	33..2093
Translation	MRLLTLLGLLCGSVATPLGPKWPEPVFGRLASPGFPGEYANDQERRWTLTAPPGYRLRLYFTHFDLELSHLCEYDFVKLSSGAKVLATLCGQESTDTERAPGKDTFYSLGSSLDITFRSDYSNEKPFTGFEAFYAAEDIDECQVAPGEAPTCDHHCHNHLGGFYCSCRAGYVLHRNKRTCSALCSGQVFTQRSGELSSPEYPRPYPKLSSCTYSISLEEGFSVILDFVESFDVETHPETLCPYDFLKIQTDREEHGPFCGKTLPHRIETKSNTVTITFVTDESGDHTGWKIHYTSTAQPCPYPMAPPNGHVSPVQAKYILKDSFSIFCETGYELLQGHLPLKSFTAVCQKDGSWDRPMPACSIVDCGPPDDLPSGRVEYITGPGVTTYKAVIQYSCEETFYTMKVNDGKYVCEADGFWTSSKGEKSLPVCEPVCGLSARTTGGRIYGGQKAKPGDFPWQVLILGGTTAAGALLYDNWVLTAAHAVYEQKHDASALDIRMGTLKRLSPHYTQAWSEAVFIHEGYTHDAGFDNDIALIKLNNKVVINSNITPICLPRKEAESFMRTDDIGTASGWGLTQRGFLARNLMYVDIPIVDHQKCTAAYEKPPYPRGSVTANMLCAGLESGGKDSCRGDSGGALVFLDSETERWFVGGIVSWGSMNCGEAGQYGVYTKVINYIPWIENIISDF

Target ORF information:

RefSeq Version	NM_006610.4
Organism	Homo sapiens(human)
Definition	Homo sapiens mannan binding lectin serine peptidase 2 (MASP2), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_006610.4

ORF Insert Sequence:

ATGAGGCTGC TGACCCTCCT GGGCCTTCTG TGTGGCTCGG TGGCCACCCC CTTGGGCCCG 
AAGTGGCCTG AACCTGTGTT CGGGCGCCTG GCATCCCCCG GCTTTCCAGG GGAGTATGCC 
AATGACCAGG AGCGGCGCTG GACCCTGACT GCACCCCCCG GCTACCGCCT GCGCCTCTAC 
TTCACCCACT TCGACCTGGA GCTCTCCCAC CTCTGCGAGT ACGACTTCGT CAAGCTGAGC 
TCGGGGGCCA AGGTGCTGGC CACGCTGTGC GGGCAGGAGA GCACAGACAC GGAGCGGGCC 
CCTGGCAAGG ACACTTTCTA CTCGCTGGGC TCCAGCCTGG ACATTACCTT CCGCTCCGAC 
TACTCCAACG AGAAGCCGTT CACGGGGTTC GAGGCCTTCT ATGCAGCCGA GGACATTGAC 
GAGTGCCAGG TGGCCCCGGG AGAGGCGCCC ACCTGCGACC ACCACTGCCA CAACCACCTG 
GGCGGTTTCT ACTGCTCCTG CCGCGCAGGC TACGTCCTGC ACCGTAACAA GCGCACCTGC 
TCAGCCCTGT GCTCCGGCCA GGTCTTCACC CAGAGGTCTG GGGAGCTCAG CAGCCCTGAA 
TACCCACGGC CGTATCCCAA ACTCTCCAGT TGCACTTACA GCATCAGCCT GGAGGAGGGG 
TTCAGTGTCA TTCTGGACTT TGTGGAGTCC TTCGATGTGG AGACACACCC TGAAACCCTG 
TGTCCCTACG ACTTTCTCAA GATTCAAACA GACAGAGAAG AACATGGCCC ATTCTGTGGG 
AAGACATTGC CCCACAGGAT TGAAACAAAA AGCAACACGG TGACCATCAC CTTTGTCACA 
GATGAATCAG GAGACCACAC AGGCTGGAAG ATCCACTACA CGAGCACAGC GCAGCCTTGC 
CCTTATCCGA TGGCGCCACC TAATGGCCAC GTTTCACCTG TGCAAGCCAA ATACATCCTG 
AAAGACAGCT TCTCCATCTT TTGCGAGACT GGCTATGAGC TTCTGCAAGG TCACTTGCCC 
CTGAAATCCT TTACTGCAGT TTGTCAGAAA GATGGATCTT GGGACCGGCC AATGCCCGCG 
TGCAGCATTG TTGACTGTGG CCCTCCTGAT GATCTACCCA GTGGCCGAGT GGAGTACATC 
ACAGGTCCTG GAGTGACCAC CTACAAAGCT GTGATTCAGT ACAGCTGTGA AGAGACCTTC 
TACACAATGA AAGTGAATGA TGGTAAATAT GTGTGTGAGG CTGATGGATT CTGGACGAGC 
TCCAAAGGAG AAAAATCACT CCCAGTCTGT GAGCCTGTTT GTGGACTATC AGCCCGCACA 
ACAGGAGGGC GTATATATGG AGGGCAAAAG GCAAAACCTG GTGATTTTCC TTGGCAAGTC 
CTGATATTAG GTGGAACCAC AGCAGCAGGT GCACTTTTAT ATGACAACTG GGTCCTAACA 
GCTGCTCATG CCGTCTATGA GCAAAAACAT GATGCATCCG CCCTGGACAT TCGAATGGGC 
ACCCTGAAAA GACTATCACC TCATTATACA CAAGCCTGGT CTGAAGCTGT TTTTATACAT 
GAAGGTTATA CTCATGATGC TGGCTTTGAC AATGACATAG CACTGATTAA ATTGAATAAC 
AAAGTTGTAA TCAATAGCAA CATCACGCCT ATTTGTCTGC CAAGAAAAGA AGCTGAATCC 
TTTATGAGGA CAGATGACAT TGGAACTGCA TCTGGATGGG GATTAACCCA AAGGGGTTTT 
CTTGCTAGAA ATCTAATGTA TGTCGACATA CCGATTGTTG ACCATCAAAA ATGTACTGCT 
GCATATGAAA AGCCACCCTA TCCAAGGGGA AGTGTAACTG CTAACATGCT TTGTGCTGGC 
TTAGAAAGTG GGGGCAAGGA CAGCTGCAGA GGTGACAGCG GAGGGGCACT GGTGTTTCTA 
GATAGTGAAA CAGAGAGGTG GTTTGTGGGA GGAATAGTGT CCTGGGGTTC CATGAATTGT 
GGGGAAGCAG GTCAGTATGG AGTCTACACA AAAGTTATTA ACTATATTCC CTGGATCGAG 
AACATAATTA GTGATTTTTA A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

MASP2 ( NM_139208.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_631947.1 Homo sapiens mannan binding lectin serine peptidase 2 (MASP2), transcript variant 2, mRNA.

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CloneID	OHu14847
Clone ID Related Accession (Same CDS sequence)	NM_139208.2 , NM_139208.3
Accession Version	NM_139208.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 558bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-02-22
Organism	Homo sapiens(human)
Product	mannan-binding lectin serine protease 2 isoform 2 precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DA638135.1, AB008047.1 and Y18281.1. This sequence is a reference standard in the RefSeqGene project. On Feb 26, 2011 this sequence version replaced NM_139208.1. Transcript Variant: This variant (2), also called MAp19, differs in the 3' UTR and 3' coding region compared to variant 1, resulting in a frameshift and upstream stop codon. Isoform 2 has a unique C-terminus and lacks the serine protease catalytic domain, compared to isoform 1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: Y18281.1, AB008047.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA2142680, SAMEA2145122 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGAGGCTGC TGACCCTCCT GGGCCTTCTG TGTGGCTCGG TGGCCACCCC CTTGGGCCCG 
AAGTGGCCTG AACCTGTGTT CGGGCGCCTG GCATCCCCCG GCTTTCCAGG GGAGTATGCC 
AATGACCAGG AGCGGCGCTG GACCCTGACT GCACCCCCCG GCTACCGCCT GCGCCTCTAC 
TTCACCCACT TCGACCTGGA GCTCTCCCAC CTCTGCGAGT ACGACTTCGT CAAGCTGAGC 
TCGGGGGCCA AGGTGCTGGC CACGCTGTGC GGGCAGGAGA GCACAGACAC GGAGCGGGCC 
CCTGGCAAGG ACACTTTCTA CTCGCTGGGC TCCAGCCTGG ACATTACCTT CCGCTCCGAC 
TACTCCAACG AGAAGCCGTT CACGGGGTTC GAGGCCTTCT ATGCAGCCGA GGACATTGAC 
GAGTGCCAGG TGGCCCCGGG AGAGGCGCCC ACCTGCGACC ACCACTGCCA CAACCACCTG 
GGCGGTTTCT ACTGCTCCTG CCGCGCAGGC TACGTCCTGC ACCGTAACAA GCGCACCTGC 
TCAGAGCAGA GCCTCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_631947.1
CDS	33..590
Translation	MRLLTLLGLLCGSVATPLGPKWPEPVFGRLASPGFPGEYANDQERRWTLTAPPGYRLRLYFTHFDLELSHLCEYDFVKLSSGAKVLATLCGQESTDTERAPGKDTFYSLGSSLDITFRSDYSNEKPFTGFEAFYAAEDIDECQVAPGEAPTCDHHCHNHLGGFYCSCRAGYVLHRNKRTCSEQSL

Target ORF information:

RefSeq Version	NM_139208.2
Organism	Homo sapiens(human)
Definition	Homo sapiens mannan binding lectin serine peptidase 2 (MASP2), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_139208.2

ORF Insert Sequence:

ATGAGGCTGC TGACCCTCCT GGGCCTTCTG TGTGGCTCGG TGGCCACCCC CTTGGGCCCG 
AAGTGGCCTG AACCTGTGTT CGGGCGCCTG GCATCCCCCG GCTTTCCAGG GGAGTATGCC 
AATGACCAGG AGCGGCGCTG GACCCTGACT GCACCCCCCG GCTACCGCCT GCGCCTCTAC 
TTCACCCACT TCGACCTGGA GCTCTCCCAC CTCTGCGAGT ACGACTTCGT CAAGCTGAGC 
TCGGGGGCCA AGGTGCTGGC CACGCTGTGC GGGCAGGAGA GCACAGACAC GGAGCGGGCC 
CCTGGCAAGG ACACTTTCTA CTCGCTGGGC TCCAGCCTGG ACATTACCTT CCGCTCCGAC 
TACTCCAACG AGAAGCCGTT CACGGGGTTC GAGGCCTTCT ATGCAGCCGA GGACATTGAC 
GAGTGCCAGG TGGCCCCGGG AGAGGCGCCC ACCTGCGACC ACCACTGCCA CAACCACCTG 
GGCGGTTTCT ACTGCTCCTG CCGCGCAGGC TACGTCCTGC ACCGTAACAA GCGCACCTGC 
TCAGAGCAGA GCCTCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

MASP2 ( NM_139208.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_631947.1 Homo sapiens mannan binding lectin serine peptidase 2 (MASP2), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu14847
Clone ID Related Accession (Same CDS sequence)	NM_139208.2 , NM_139208.3
Accession Version	NM_139208.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 558bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2020-01-01
Organism	Homo sapiens(human)
Product	mannan-binding lectin serine protease 2 isoform 2 precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DA638135.1, AB008047.1 and Y18281.1. This sequence is a reference standard in the RefSeqGene project. On May 31, 2019 this sequence version replaced NM_139208.2. Transcript Variant: This variant (2), also called MAp19, differs in the 3' UTR and 3' coding region compared to variant 1, resulting in a frameshift and upstream stop codon. Isoform 2 has a unique C-terminus and lacks the serine protease catalytic domain, compared to isoform 1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: Y18283.1, Y18281.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA2142680, SAMEA2145122 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGAGGCTGC TGACCCTCCT GGGCCTTCTG TGTGGCTCGG TGGCCACCCC CTTGGGCCCG 
AAGTGGCCTG AACCTGTGTT CGGGCGCCTG GCATCCCCCG GCTTTCCAGG GGAGTATGCC 
AATGACCAGG AGCGGCGCTG GACCCTGACT GCACCCCCCG GCTACCGCCT GCGCCTCTAC 
TTCACCCACT TCGACCTGGA GCTCTCCCAC CTCTGCGAGT ACGACTTCGT CAAGCTGAGC 
TCGGGGGCCA AGGTGCTGGC CACGCTGTGC GGGCAGGAGA GCACAGACAC GGAGCGGGCC 
CCTGGCAAGG ACACTTTCTA CTCGCTGGGC TCCAGCCTGG ACATTACCTT CCGCTCCGAC 
TACTCCAACG AGAAGCCGTT CACGGGGTTC GAGGCCTTCT ATGCAGCCGA GGACATTGAC 
GAGTGCCAGG TGGCCCCGGG AGAGGCGCCC ACCTGCGACC ACCACTGCCA CAACCACCTG 
GGCGGTTTCT ACTGCTCCTG CCGCGCAGGC TACGTCCTGC ACCGTAACAA GCGCACCTGC 
TCAGAGCAGA GCCTCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_631947.1
CDS	33..590
Translation	MRLLTLLGLLCGSVATPLGPKWPEPVFGRLASPGFPGEYANDQERRWTLTAPPGYRLRLYFTHFDLELSHLCEYDFVKLSSGAKVLATLCGQESTDTERAPGKDTFYSLGSSLDITFRSDYSNEKPFTGFEAFYAAEDIDECQVAPGEAPTCDHHCHNHLGGFYCSCRAGYVLHRNKRTCSEQSL

Target ORF information:

RefSeq Version	NM_139208.3
Organism	Homo sapiens(human)
Definition	Homo sapiens mannan binding lectin serine peptidase 2 (MASP2), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_139208.3

ORF Insert Sequence:

ATGAGGCTGC TGACCCTCCT GGGCCTTCTG TGTGGCTCGG TGGCCACCCC CTTGGGCCCG 
AAGTGGCCTG AACCTGTGTT CGGGCGCCTG GCATCCCCCG GCTTTCCAGG GGAGTATGCC 
AATGACCAGG AGCGGCGCTG GACCCTGACT GCACCCCCCG GCTACCGCCT GCGCCTCTAC 
TTCACCCACT TCGACCTGGA GCTCTCCCAC CTCTGCGAGT ACGACTTCGT CAAGCTGAGC 
TCGGGGGCCA AGGTGCTGGC CACGCTGTGC GGGCAGGAGA GCACAGACAC GGAGCGGGCC 
CCTGGCAAGG ACACTTTCTA CTCGCTGGGC TCCAGCCTGG ACATTACCTT CCGCTCCGAC 
TACTCCAACG AGAAGCCGTT CACGGGGTTC GAGGCCTTCT ATGCAGCCGA GGACATTGAC 
GAGTGCCAGG TGGCCCCGGG AGAGGCGCCC ACCTGCGACC ACCACTGCCA CAACCACCTG 
GGCGGTTTCT ACTGCTCCTG CCGCGCAGGC TACGTCCTGC ACCGTAACAA GCGCACCTGC 
TCAGAGCAGA GCCTCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

MASP2 ( XM_017000097.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_016855586.1 Homo sapiens mannan binding lectin serine peptidase 2 (MASP2), transcript variant X2, mRNA.

Price & Availability↑

CloneID	OHu83031
Clone ID Related Accession (Same CDS sequence)	XM_017000097.1
Accession Version	XM_017000097.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 999bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	mannan-binding lectin serine protease 2 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000001.11) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGAGGCTGC TGACCCTCCT GGGCCTTCTG TGTGGCTCGG TGGCCACCCC CTTGGGCCCG 
AAGTGGCCTG AACCTGTGTT CGGGCGCCTG GCATCCCCCG GCTTTCCAGG GGAGTATGCC 
AATGACCAGG AGCGGCGCTG GACCCTGACT GCACCCCCCG GCTACCGCCT GCGCCTCTAC 
TTCACCCACT TCGACCTGGA GCTCTCCCAC CTCTGCGAGT ACGACTTCGT CAAGCTGAGC 
TCGGGGGCCA AGGTGCTGGC CACGCTGTGC GGGCAGGAGA GCACAGACAC GGAGCGGGCC 
CCTGGCAAGG ACACTTTCTA CTCGCTGGGC TCCAGCCTGG ACATTACCTT CCGCTCCGAC 
TACTCCAACG AGAAGCCGTT CACGGGGTTC GAGGCCTTCT ATGCAGCCGA GGACATTGAC 
GAGTGCCAGG TGGCCCCGGG AGAGGCGCCC ACCTGCGACC ACCACTGCCA CAACCACCTG 
GGCGGTTTCT ACTGCTCCTG CCGCGCAGGC TACGTCCTGC ACCGTAACAA GCGCACCTGC 
TCAGCCCTGT GCTCCGGCCA GGTCTTCACC CAGAGGTCTG GGGAGCTCAG CAGCCCTGAA 
TACCCACGGC CGTATCCCAA ACTCTCCAGT TGCACTTACA GCATCAGCCT GGAGGAGGGG 
TTCAGTGTCA TTCTGGACTT TGTGGAGTCC TTCGATGTGG AGACACACCC TGAAACCCTG 
TGTCCCTACG ACTTTCTCAA GATTCAAACA GACAGAGAAG AACATGGCCC ATTCTGTGGG 
AAGACATTGC CCCACAGGAT TGAAACAAAA AGCAACACGG TGACCATCAC CTTTGTCACA 
GATGAATCAG GAGACCACAC AGGCTGGAAG ATCCACTACA CGAGCACAGA ACTTCAGATG 
GCTCGATTCA GTCTTGGCTG CTGTAGACCA CATGAAAACC AACAAGCCTG GTTTCCTCTG 
CGCAGCGCAG CCTTGCCCTT ATCCGATGGC GCCACCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_016855586.1
CDS	33..1031
Translation	MRLLTLLGLLCGSVATPLGPKWPEPVFGRLASPGFPGEYANDQERRWTLTAPPGYRLRLYFTHFDLELSHLCEYDFVKLSSGAKVLATLCGQESTDTERAPGKDTFYSLGSSLDITFRSDYSNEKPFTGFEAFYAAEDIDECQVAPGEAPTCDHHCHNHLGGFYCSCRAGYVLHRNKRTCSALCSGQVFTQRSGELSSPEYPRPYPKLSSCTYSISLEEGFSVILDFVESFDVETHPETLCPYDFLKIQTDREEHGPFCGKTLPHRIETKSNTVTITFVTDESGDHTGWKIHYTSTELQMARFSLGCCRPHENQQAWFPLRSAALPLSDGAT

Target ORF information:

RefSeq Version	XM_017000097.1
Organism	Homo sapiens(human)
Definition	Homo sapiens mannan binding lectin serine peptidase 2 (MASP2), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017000097.1

ORF Insert Sequence:

ATGAGGCTGC TGACCCTCCT GGGCCTTCTG TGTGGCTCGG TGGCCACCCC CTTGGGCCCG 
AAGTGGCCTG AACCTGTGTT CGGGCGCCTG GCATCCCCCG GCTTTCCAGG GGAGTATGCC 
AATGACCAGG AGCGGCGCTG GACCCTGACT GCACCCCCCG GCTACCGCCT GCGCCTCTAC 
TTCACCCACT TCGACCTGGA GCTCTCCCAC CTCTGCGAGT ACGACTTCGT CAAGCTGAGC 
TCGGGGGCCA AGGTGCTGGC CACGCTGTGC GGGCAGGAGA GCACAGACAC GGAGCGGGCC 
CCTGGCAAGG ACACTTTCTA CTCGCTGGGC TCCAGCCTGG ACATTACCTT CCGCTCCGAC 
TACTCCAACG AGAAGCCGTT CACGGGGTTC GAGGCCTTCT ATGCAGCCGA GGACATTGAC 
GAGTGCCAGG TGGCCCCGGG AGAGGCGCCC ACCTGCGACC ACCACTGCCA CAACCACCTG 
GGCGGTTTCT ACTGCTCCTG CCGCGCAGGC TACGTCCTGC ACCGTAACAA GCGCACCTGC 
TCAGCCCTGT GCTCCGGCCA GGTCTTCACC CAGAGGTCTG GGGAGCTCAG CAGCCCTGAA 
TACCCACGGC CGTATCCCAA ACTCTCCAGT TGCACTTACA GCATCAGCCT GGAGGAGGGG 
TTCAGTGTCA TTCTGGACTT TGTGGAGTCC TTCGATGTGG AGACACACCC TGAAACCCTG 
TGTCCCTACG ACTTTCTCAA GATTCAAACA GACAGAGAAG AACATGGCCC ATTCTGTGGG 
AAGACATTGC CCCACAGGAT TGAAACAAAA AGCAACACGG TGACCATCAC CTTTGTCACA 
GATGAATCAG GAGACCACAC AGGCTGGAAG ATCCACTACA CGAGCACAGA ACTTCAGATG 
GCTCGATTCA GTCTTGGCTG CTGTAGACCA CATGAAAACC AACAAGCCTG GTTTCCTCTG 
CGCAGCGCAG CCTTGCCCTT ATCCGATGGC GCCACCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Serine proteases of the complement lectin pathway and their genetic variations in ischaemic stroke.
Journal of clinical pathology71(2)141-147(2018 Feb)
Tsakanova G,Stepanyan A,Nahapetyan K,Sim RB,Arakelyan A,Boyajyan A

Incident microalbuminuria and complement factor mannan-binding lectin-associated protein 19 in people with newly diagnosed type 1 diabetes.
Diabetes/metabolism research and reviews33(5)(2017 Jul)
?stergaard JA,Thiel S,Hoffmann-Petersen IT,Hovind P,Parving HH,Tarnow L,Rossing P,Hansen TK

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MASP2 cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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